Relevant bibliographies by topics / Platinum

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  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
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Academic literature on the topic 'Platinum'

Author: Grafiati
Published: 4 June 2021
Last updated: 11 January 2025

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Journal articles on the topic "Platinum"

1

Tokura, Yuki, Shino Toma, Daisuke Takimoto, and Wataru Sugimoto. "Oxygen Reduction Reaction Activity of Platinum Nanosheets Derived from Layered Platinic Acid." ECS Meeting Abstracts MA2023-02, no. 40 (December 22, 2023): 1951. http://dx.doi.org/10.1149/ma2023-02401951mtgabs.

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Platinum nanoparticles are mainly utilized as the cathode catalyst for polymer electrolyte fuel cells. However, the utilization of platinum for the oxygen reduction reaction (ORR) is insufficient and one must tackle the trade-off between high surface area and high stability. We have previously shown that metallic nanosheets such as ruthenium nanosheets exhibit high electrocatalytic activity and stability owing to the two-dimensional structure with an atomic scale thickness.1, 2 Platinum nanosheets, if available, should also have the potential to increase the utilization of the atoms and durability. While a few studies have reported the synthesis of platinum nanosheets,3 the thickness of the nanosheets is more than 1 nm, and the utilization of platinum has so far been lower than that of the Pt nanoparticles. In this study, we report double-layered platinum nanosheets derived from layered platinic acid.4 Layered platinic acid was synthesized through a solid-state-reaction and subsequent acid treatment. From the layered platinic acid, platinum oxide nanosheets were obtained as a colloid via chemical exfoliation. The thickness of the platinum oxide nanosheet was ~0.9 nm, consistent with the thickness of a single PtO6 octahedron. The platinum oxide nanosheets on silicon wafer were topotactically reduced to platinum nanosheets by mild thermal treatment in hydrogen. The thickness of the platinum nanosheet was ~0.5 nm, corresponding to a two atomic layer platinum nanosheet. Carbon supported platinum nanosheets were prepared by the reduction of platinum oxide nanosheets supported on carbon. The electrochemically active surface area (ECSA) of the carbon supported platinum nanosheets was 100 to 120 m2 (g-Pt)-1, which was considerably larger than that of 3 nm platinum nanoparticle (80 m2 (g-Pt)-1). In addition, the platinum nanosheet showed 1.7 times higher mass activity towards the oxygen reduction reaction compared to that of 3 nm platinum nanoparticles. Various methods for the topotactic reduction of platinum oxide nanosheets on carbon was studied. In addition to the mild thermal treatment in hydrogen gas, electrochemical reduction was also conducted. The ECSA of the platinum nanosheet prepared by electrochemical reduction at constant potential was 100 to 120 m2 (g-Pt)-1, which was almost same as the platinum nanosheet reduced by the mild thermal treatment in hydrogen. The specific activity was 1.2 to 1.3 times higher than that of the platinum nanosheet reduced by the mild thermal treatment in hydrogen. Therefore, the platinum nanosheet reduced by electrochemical reduction showed high mass activity for ORR. Acknowledgement This work was supported as part of the “Polymer Electrolyte Fuel Cell Program” and the FC-Platform projects from the New Energy and Industrial Technology Development Organization (NEDO) of Japan (20001201-0, 22101136-0). References [1] D. Takimoto, W. Sugimoto, Q. Yuan, N. Takao, T. Itoh, T. V. T. Duy, T. Ohwaki and H. Imai, ACS Appl. Nano Mater. 2, 5743 (2019). [2] W. Sugimoto and D. Takimoto, Chem. Lett. 50, 1304 (2021). [3] A. Funatsu, H. Tateishi, K. Hatakeyama, Y. Fukunaga, T. Taniguchi, M. Koinuma, H. Matsuura and Y. Matsumoto, Chem. Commun. 50, 8503 (2014). [4] D. Takimoto, S. Toma, Y. Suda, T. Shirokura, Y. Tokura, K. Fukuda, M. Matsumoto, H. Imai and W. Sugimoto, Nat. Commun. 14, 19 (2023).
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2

Wolford, Juliet Elizabeth, Jiaru Bai, Ramez Hassef Eskander, Robin Keller, Lindsey E. Minion, John K. Chan, Bradley J. Monk, and Krishnansu Sujata Tewari. "Evaluating the cost-effectiveness of current FDA-approved PARP inhibitors for the treatment of recurrent ovarian cancer." Journal of Clinical Oncology 35, no. 15_suppl (May 20, 2017): 5516. http://dx.doi.org/10.1200/jco.2017.35.15_suppl.5516.

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5516 Background: Unlike approved IV administered therapies, Medicare is under no obligation to cover prescription medicines. We sought to evaluate the cost-effectiveness of the two FDA-approved orally administered PARP inhibitors (PARPi), olaparib and rucaparib. Methods: A Markov model was created in TreeAge Pro 2015 with nodes in the chain allowing patients to transition through response, hematological complications, non-hematological complications, progression, and death. Separately, the PARP inhibitors were compared with IV administered drugs approved for recurrent ovarian cancers including platinum-based, non-platinum, and bevacizumab-based regimens. Toxicity and mean PFS rates for the different agents were obtained from registration trial data. Costs of IV chemotherapy, managing toxicities, infusions, and supportive care were estimated using 2015 Medicare data. Incremental cost-effectiveness ratios (ICER) were calculated and survival was reported in quality adjusted life months. Results: Platinum-based combinations were the most cost-effective at $1,672/PFS mo as compared to non-platinum agents ($6,688/mo), bevacizumab-containing regimens ($12,482/mo), olaparib ($13,3731/mo), and rucaparib ($14,034/mo). Considering a cost of $114,478 for olaparib and $137,068 for rucaparib prior to progression, costs associated with PARPi were 7.1 to 8.3X more than platinum combinations. To better compare the registration trial data to PARPi data, probability was adjusted to 2nd line for rucaparib, revealing it’s ICERs’ of per month of life added to be $26,997 for bevacizumab, $17,757 for non-platinum, and $79,585 for platinums. Using the adjusted-to-2nd-line probabilities for olaparib, exhibited ICERs were $16,549 for bevacizumab, $25,637 for non-platinums and $72,083 for platinums. Conclusions: The high costs of PARPi were not balanced by costs of infusion and managing toxicities of IV drugs typically associated with lower response rates and shorter PFS in the recurrent space. Balancing incremental clinical benefit with novel therapies remains problematic and could widen disparities among those with limited access to care.
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3

Tofan, Lavinia, Carmen Păduraru, Laura Bulgariu, and Rodica Wenkert. "Perspectives on Analytical Methodology of Platinum Metals." Advanced Materials Research 95 (January 2010): 9–16. http://dx.doi.org/10.4028/www.scientific.net/amr.95.9.

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In last years there is paid a special attention to the analytical chemistry of platinic metals (rhutenium, osmium, platinum, iridium, palladium, rhodium), due to increasing concerns on recovery and recirculation of these metals, especially platinum. In this context, recent data of specialty literature, regarding the approach of new methodological and chemical techniques in platinum metals determination from a variety of complex matrices and wide ranges of concentrations are systematized and briefly discussed.
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Shtemenko, A. V., and N. I. Shtemenko. "Rhenium–platinum antitumor systems." Ukrainian Biochemical Journal 89, no. 2 (April 24, 2017): 5–30. http://dx.doi.org/10.15407/ubj89.02.005.

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Bulgakov, Roman A., Nina A. Kuznetsova, Olga V. Dolotova, Ludmila I. Solovieva, John Mack, Wadzanai J. U. Chidawanyika, Oleg L. Kaliya, and Tebello Nyokong. "Synthesis and photophysical properties of covalent conjugates of aqua platinum(II) and octacarboxy-substituted zinc phthalocyanine." Journal of Porphyrins and Phthalocyanines 16, no. 11 (October 22, 2012): 1217–24. http://dx.doi.org/10.1142/s1088424612501209.

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New covalent conjugates of aqua platinum(II) and octacarboxy-substituted zinc phthalocyanine, bearing one, two, three and four aqua platinum moieties on the periphery of the Pc ligand have been synthesized and characterized. The effect of the stepwise introduction of the aqua platinums on the photophysical and photochemical properties of these compounds has been investigated in dimethylsulfoxide solution. It has been found that aqua platinum moieties have only a limited effect on the dynamics of the singlet and triplet excited states, on the ability to sensitize singlet oxygen formation and on the photostability. Each conjugate has a high singlet oxygen quantum yield (ΦΔ 0.51–0.62) and thus retains potential for use as a dual action anticancer drugs by acting as a sensitizer for PDT in addition to the likely chemotherapeutic effects of the Pt(II) complexes.
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Tokura, Yuki, Junke Zhang, Daisuke Takimoto, and Wataru Sugimoto. "Effect of Reduction Method for Carbon Supported Platinum Nanosheet with High Surface Area and Activity." ECS Meeting Abstracts MA2024-02, no. 41 (November 22, 2024): 2628. https://doi.org/10.1149/ma2024-02412628mtgabs.

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Carbon supported platinum nanoparticle is utilized as the cathode catalyst for polymer electrolyte fuel cells. However, the efficiency is about 40% (60% of platinum exist inside nanoparticle) for commercial 2-3 nm diameter platinum and thus there is still room for improvement. One of the approaches to enhance the platinum efficiency is the use of smaller sized nanoparticles. However, smaller nanoparticles generally have lower specific activity and durability. Therefore, one must overcome the trade-off between high surface area and high stability. We have succeeded in the exfoliation of layered platinic acid to platinum oxide nanosheets and subsequent reduction to platinum nanosheets with an average thickness of ~0.5 nm (2 atomic layers). The carbon supported platinum nanosheets showed higher electrochemically active surface area (ECSA) and ORR mass activity than conventional carbon supported 3 nm platinum nanoparticles. Moreover, the carbon supported platinum nanosheets exhibited higher load-cycle durability owing to the high coordination number of surface atoms of platinum nanosheets. However, the nanosheets were partially aggregated and transformed to nanoparticles, resulting in platinum efficiency of about 60% of theoretical surface area. In this study, we discuss the topotactic reduction of carbon supported platinum oxide nanosheets via mild treatment such as vapor phase reduction with hydrogen gas and/or carbon monoxide for further improvement of ECSA and ORR activity. The ECSA of the carbon supported platinum nanosheets reduced by the thermal treatment under hydrogen gas at 100 ℃ (Pt(ns)/C-H2) was 100 to 120 m2 (g-Pt)-1, which is higher than 3 nm platinum nanoparticles (80 m2 (g-Pt)-1). The ECSA of the carbon supported platinum nanosheets reduced by carbon monoxide gas at 25 ℃ (Pt(ns)/C-CO) was 133 m2 (g-Pt)-1. It is considered that carbon monoxide adsorbed on reduced platinum atoms, leading to suppression of aggregation and growth of platinum. The ORR specific activity of Pt(ns)/C-H2 was 300-350 μA cm-2, while that of Pt(ns)/C-CO was 150 μA cm-2 which is half of Pt(ns)/C-H2. From cyclic voltammograms (Figure 1), the peak potential for the reduction of platinum oxide of Pt(ns)/C-CO showed lower potential than that of Pt(ns)/C-H2. This suggests that Pt(ns)/C-CO has a more unstable surface than Pt(ns)/C-H2, and Pt−OHad and/or Pt−Oad formed more on platinum surface, lowering the ORR. As a result of the high ECSA, the ORR mass activity of Pt(ns)/C-H2 was 1.7 times higher compared to that of 3 nm platinum nanoparticles, while that of Pt(ns)/C-CO was almost same as 3 nm platinum nanoparticles despite the higher ECSA. This work was supported in part by the “Polymer Electrolyte Fuel Cell Program” and the FC-Platform projects from the New Energy and Industrial Technology Development Organization (NEDO) of Japan (20001201-0, 22101136-0). [1] D. Takimoto, S. Toma, Y. Suda, T. Shirokura, Y. Tokura, K. Fukuda, M. Matsumoto, H. Imai and W. Sugimoto, Nat. Commun. 14, 19 (2023). Figure 1
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Troche, Kyle, Jamin R. Pillars, and Fernando H. Garzon. "Analytical Electrochemistry of Nickel and Platinum Electrolytes." ECS Meeting Abstracts MA2024-02, no. 22 (November 22, 2024): 1850. https://doi.org/10.1149/ma2024-02221850mtgabs.

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Pt-Ni alloys possess unique catalytic and magnetic properties, and it is highly desirable to synthesize conformal thin films of these materials for integration into magnetic devices and energy conversion systems. Electrodeposition provides large scale and complex form plating without the need for additional equipment such as a vacuum system or furnace used in traditional Pt-Ni synthesis. While nickel and platinum electrodepositions can individually plate effectively, co-deposition provides its own challenges. Large differences in deposition potentials between the two metals and platinum’s reduced overpotential for undesirable hydrogen evolution are necessary challenges that need to be addressed. Investigation into various nickel and platinum bath chemistries over a range of pH’s will help develop a Pt-Ni co-deposition bath that will produce a uniform deposition with desired morphologies. A rotating disk electrode experiment was conducted on each electrodeposition bath along with a Koutecky-Levich analysis to determine the baths diffusion coefficient and rate constant. Nickel baths include boric acid, acetic acid, citric acid, hydrochloric acid, and phosphoric acid. Platinum baths include hydrochloric acid and acetic acid. Hydrogen suppression techniques were also studied for both nickel and platinum baths to determine the effect on hydrogen generation and metal deposition. Successful suppression of the hydrogen generation reaction would result in greater control of nickel deposition onto platinum as well as thicker platinum films.
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Wu, Baoyuan, and Ge Liu. "Platinum: Platinum-Rhodium Thermocouple Wire." Platinum Metals Review 41, no. 2 (April 1, 1997): 81–85. http://dx.doi.org/10.1595/003214097x4128185.

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A new type of platinum:platinum-rhodium thermocouple wire which incorporates traces of yttrium in the platinum limb has been developed and tested in some typical working environments. This thermocouple possesses good thermal stability and mechanical strength at high temperatures, and a long service life, compared with conventional platinum:platinum-rhodium thermocouples. The thermocouple meets the output requirements of the Type S standard for thermocouples — those made of Pt:Pt-10%Rh — whose manufacturing tolerances are prescribed by the International Electrotechnical Commission (I.E.C.)(l). The life of thermocouples made from this wire is increased by around 1.5 to 2 times and they display a greater resistance to contamination.
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Connors, Jeremy, Linda Zhang, Hidetaka Uryu, Koji Sasaki, Jennifer Padilla, Zongrui Li, Ken Furudate, et al. "Distinct Impact of Platinum Chemotherapies on the Fitness and Genome of Hematopoietic Stem Cells and the Risk of Therapy-Related Myeloid Neoplasms." Blood 144, Supplement 1 (November 5, 2024): 1816. https://doi.org/10.1182/blood-2024-212052.

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The widespread use of platinum-based chemotherapy has been associated with an increased incidence of therapy-related myeloid neoplasms (t-MNs). Among the three most commonly used platinum-cisplatin, carboplatin, and oxaliplatin-oxaliplatin presents a distinctive clinical usage and toxicity. This distinction is supported by a previous study, which postulated that oxaliplatin-induced cytotoxicity primarily results from ribosomal stress as opposed to a DNA-damage response. Additionally, anecdotal data suggest a lower incidence of t-MNs associated with oxaliplatin. To investigate the differential risk of t-MNs among the various platinum chemotherapies, we analyzed data from 52,179 patients with diverse cancer types who received one of the platinum chemotherapies at our hospital. Of these patients, 22,652 (44%) received carboplatin alone, 15,358 (30%) received cisplatin alone, 8,805 (17%) received oxaliplatin alone, and 5,364 (9%) received multiple combinations of platinums. A total of 171 patients developed t-MNs, with only 6% of these patients having been exposed to oxaliplatin. There was no significant difference in the prevalence of TP53 mutations among t-MNs associated with different platinum exposures (56%, 60%, and 60% for cisplatin, carboplatin, and oxaliplatin, respectively). The cumulative incidence risk of t-MNs, using the Fine and Gray model, was significantly lower for patients treated with oxaliplatin alone compared to those receiving cisplatin alone (HR 0.39 [95% CI: 0.2-0.75], P = 0.005) or carboplatin alone (HR 0.42 [95% CI: 0.22-0.78], P = 0.01). Multivariate Fine and Gray models adjusting for other chemotherapy exposures also indicated that oxaliplatin treatment was associated with a significantly lower risk of t-MNs (HR 0.49 [95% CI: 0.26-0.9], P = 0.02). To explore the mechanisms underlying the protective effect of oxaliplatin on t-MN risk, we hypothesized that oxaliplatin treatment does not confer a selective advantage to mutant hematopoietic stem cells (HSCs), given that the selective expansion of mutant HSCs (such as TP53 or PPM1D) under chemotherapy has been implicated in the development of t-MNs. To test this hypothesis, we generated a chimeric mouse transplant model with Trp53-/- or Ppm1d truncating mutant cells (Ppm1d Tr/+) transplanted with wild-type cells in a 1:9 ratio. Recipient mice were treated with either vehicle, cisplatin, or oxaliplatin. Contrary to our hypothesis, both Trp53-/- and Ppm1d Tr/+ cells showed significant clonal expansion after both cisplatin and oxaliplatin treatment compared to vehicle. Thus, the reduced risk of t-MNs with oxaliplatin treatment cannot be attributed to reduced selective pressure of oxaliplatin compared to other platinums. We then hypothesized that oxaliplatin exerts less genotoxic effect on HSCs compared to other platinums. To test this hypothesis, we generated single-cell-derived HSC colonies from the recipient mice described above and performed whole-genome sequencing of individual colonies to measure platinum-induced somatic mutations in HSCs. Oxaliplatin-treated HSCs exhibited significantly fewer total somatic mutations compared to cisplatin-treated HSCs (mean: 524 vs. 891 mutations, P < 0.0001) and were comparable to vehicle-treated HSCs (mean: 524 vs. 485 mutations, P = 0.49). Mutation signature analysis revealed that a median of 74% (range: 52-100) of somatic mutations were attributed to known platinum signatures (SBS31 and SBS35) in cisplatin-treated HSCs, whereas a median of 34% (range: 25-41) of mutations in oxaliplatin-treated HSCs were platinum-associated (P < 0.001). In summary, while oxaliplatin treatment imposed a similar degree of selective pressure and promoted the expansion of TP53 and PPM1D mutated HSCs compared to other platinums, it induced significantly fewer somatic mutations in HSCs. These data align with clinical findings that the risk of t-MNs is significantly lower for patients treated with oxaliplatin. Nevertheless, t-MNs that do develop after oxaliplatin treatment still exhibit a high prevalence of TP53 mutations, consistent with our findings that oxaliplatin confers a similar selective advantage to TP53-mutated HSCs. These insights enhance our understanding of t-MN pathogenesis and aid in the development of strategies to mitigate this risk.
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Muenchen, H. J., S. K. Aggarwal, H. K. Misra, and P. J. Andrulis. "Morphological and Histochemical Changes in Macrophage Activity After Novel Anti-Neoplastic Platinum Agents." Microscopy and Microanalysis 3, S2 (August 1997): 11–12. http://dx.doi.org/10.1017/s1431927600006942.

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Poly-[(trans-1,2-diaminocyclohexane) platinumj-carboxyamylose (“poly-plat”), 5-sulfosalicylato-trans -(1,2-diaminocyclohexane) platinum (SSP), and 4-hydroxy-∝-sulfonylphenylacetato (trans 1,2-diaminocyclohexane) platinum (II) (SAP) are second generation analogs of cisplatin (CDDP) with higher efficacy and potency than cisplatin. This is particularly true of “poly-plat” which contains 1/5 the platinum of CDDP. In order to understand the mechanism of action of these compounds, isolated murine peritoneal macrophages in culture medium were treated with “poly-plat”, SSP, or SAP (5 μg/ml) for 2 h. Drug containing medium was then replaced with fresh medium and the cells were allowed to incubate at 37° C (5% CO2) for 24 h. Supernatants were collected at 0.5, 1, 2, and 24 h post-treatment for immunocytochemical analysis. Confocal microscopy studies demonstrated an increase in the number of lysosomes in the treated macrophages, but only “poly-plat” and SSP treated macrophages were stimulated to form cytoplasmic extensions at 2 h and 24 h.
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Dissertations / Theses on the topic "Platinum"

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Soames, Mark. "Sol-gel routes to platinum, platinum-tin and platinum-potassium reforming catalysts." Thesis, Brunel University, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.311280.

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Müller, Lydia, Daniel Gerighausen, Mariam Farman, and Dirk Zeckzer. "Sierra platinum." Universitätsbibliothek Leipzig, 2016. http://nbn-resolving.de/urn:nbn:de:bsz:15-qucosa-216471.

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Background: Histone modifications play an important role in gene regulation. Their genomic locations are of great interest. Usually, the location is measured by ChIP-seq and analyzed with a peak-caller. Replicated ChIP-seq experiments become more and more available. However, their analysis is based on single-experiment peak-calling or on tools like PePr which allows peak-calling of replicates but whose underlying model might not be suitable for the conditions under which the experiments are performed. Results: We propose a new peak-caller called \"Sierra Platinum\" that allows peak-calling of replicated ChIP-seq experiments. Moreover, it provides a variety of quality measures together with integrated visualizations supporting the assessment of the replicates and the resulting peaks, as well as steering the peak-calling process. Conclusion: We show that Sierra Platinum outperforms currently available methods using a newly generated benchmark data set and using real data from the NIH Roadmap Epigenomics Project. It is robust against noisy replicates.
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Pugh, Dylan Vicente. "Nanoporous Platinum." Diss., Virginia Tech, 2003. http://hdl.handle.net/10919/27256.

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Dealloying is a corrosion process in which one or more elements are selectively removed from an alloy leading to a 3-dimensional porous structure of the more noble element(s). These porous structures have been known to cause stress corrosion cracking in noble metal alloy systems but more recent interest in using the corrosion process to produce porous metals has developed. Applications for these structures range from high surface area electrodes for biomedical sensors to use as skeletal structures for fundamental studies (e.g. low temperature heat exchangers or sensitivity of surface diffusivity to chemical environment). In this work we will review our current understanding of alloy corrosion including our most recent results demonstrating a more accurate method for calculating alloy critical potential based on potential hold experiments. The critical potentials calculated through the potential hold method were â 0.030VMSE, 0.110VMSE, and 0.175VMSE for Cu80Pt20, Cu75Pt25 Cu71Pt29 respectively. We will present the use of porous metals for making surface diffusivity measurements in the Pt systems as a function of chemical environment. A review of the use of small angle neutron scattering to make accurate measurements of pore size is presented and the sensitivity of pore size to electrolyte, electrolyte composition, applied potential and temperature will be explained. The production of porous Pt with pore sizes ranging from 2-200nm is demonstrated.
Ph. D.
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Dhavale, V. M. "Low-platinum and platinum-free electrocatalysts for energy applications." Thesis(Ph.D.), CSIR-National Chemical Laboratory, Pune, 2015. http://dspace.ncl.res.in:8080/xmlui/handle/20.500.12252/1994.

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Lee, Daniel E. "Development of Non-Traditional Platinum Anticancer Agents: trans-Platinum Planar Amine Compounds and Polynuclear Platinum Compounds." VCU Scholars Compass, 2015. http://scholarscompass.vcu.edu/etd/3809.

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Development of Non-Traditional Platinum Anticancer Agents: trans-Platinum Planar Amine Compounds and Polynuclear Platinum Compounds By Daniel E. Lee, Ph.D. A dissertation submitted in partial fulfillment of the requirements for the degree of Doctor of Philosophy at Virginia Commonwealth University. Virginia Commonwealth University, 2015 Major Director: Nicholas P Farrell, Ph.D., Professor, Department of Chemistry Platinum anticancer compounds with cis geometry, similar to cisplatin, have been explored to circumvent the cisplatin resistance; however, they were not considered broadly active in cisplatin cells due to exhibiting similar or same cell death mechanism as cisplatin. Platinum compounds with trans geometry were less studied due to transplatin being clinically inactive; but with few structural modifications, they resulted in unaffected cytotoxic activities in cisplatin resistant cells with structural modification by exhibiting different modes of DNA binding. This research focused on further exploring and establishing structure-activity relationship of two promising non-classical series of platinum compounds with trans-geometry: trans-platinum planar amine (TPA) compounds and noncovalently binding polynuclear platinum compounds (PPC-NC). During this research, further optimizations of the reactivity of TPA compounds were accomplished by modifying the leaving carboxylate groups. The effects of modified reactivity were probed by a systematic combination of chemical and biophysical assays, followed by evaluating their biological effects in cells. To establish the structural-activity relationship of PPC-NCs, Mono-, Di-, Tri-, and Tetraplatin NC with charge of 4+, 6+, 8+, and 10+ were synthesized and evaluated by utilizing biophysical and biological assays. Lastly, a new class of polynuclear platinum compounds, Hybrid-PPCs, were synthesized and evaluated to overcome the pharmacokinetic problems of BBR3464, phase II clinical trial anticancer drug developed previously in our laboratory.
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Aslam, Toseef. "Reforming of hydrocarbons on supported platinum and platinum-tin catalysts." Thesis, University of Reading, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.405472.

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Morimoto, Yu. "Electrochemical oxidation of methanol on platinum and platinum based electrodes." Case Western Reserve University School of Graduate Studies / OhioLINK, 1995. http://rave.ohiolink.edu/etdc/view?acc_num=case1058206604.

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Sun, Grace Siswanto. "Simulations of platinum growth on Pt(111) using density functional theory and kinetic monte carlo simulations /." Thesis, Connect to this title online; UW restricted, 2000. http://hdl.handle.net/1773/9672.

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Sivalingam, Juvarajan. "Hydrogenolysis and reforming properties of platinum and platinum-tin supported catalysts." Thesis, Brunel University, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.303969.

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Al, Onazi Fahad Nasser. "Platinum drugs given in combination with phytochemicals to enhance platinum action." Thesis, The University of Sydney, 2017. http://hdl.handle.net/2123/18971.

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This study focused on the sequenced combinations of platinum drugs cisplatin and oxaliplatin and four phytochemicals celastrol, guggulsterone, garcinol and ellagic acid administered to human ovarian lines A2780, A2780cisR and A2780ZD0473R. Among the phytochemicals, celastrol is most active having comparable activity against all the three ovarian tumour models. As applied to binary combinations of platinum drugs and the phytochemicals, it was found that generally synergism was greater at higher concentrations (ED75 and ED90) of drugs than at lower concentrations (ED50) in all three cell lines. Often 0/0 h and 0/4 h sequences of administration were found to be more synergistic, giving support to the idea that pre-treatment or concurrent with the phytochemicals have served to activate the cancer cells towards assault by the platinum drugs. The reduced accumulation of platinum in the cisplatin resistant cell line A2780cisR as compared to the cisplatin sensitive cell line A2780, gives support to the concept that the reduced platinum accumulation is the principal mechanism by which the cisplatin resistant cell line A2780cisR cell line resist the platinum drugs action. The absence of any visible DNA band after interaction of A2780 cells with ellagic acid indicates total DNA damage so that the phytochemical is most damaging to DNA in A2780 cells. The results of the present study showed the levels of reduced form of glutathione (GSH) in the resistant cell line A2780cisR were higher than the parent cell line A2780, irrespective of whether the cells were treated with a single agent (cisplatin, oxaliplatin, or ellagic acid) or in combination, giving support to the idea that the higher levels of glutathione serve to be one of the central mechanisms of cisplatin resistance in ovarian cancer cells.
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Books on the topic "Platinum"

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International Program on Chemical Safety, United Nations Environment Programme, and International Labour Organisation, eds. Platinum. Geneva: World Health Organization, 1991.

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Canada. Energy, Mines and Resources Canada., ed. Platinum. Canada: Energy, Mines and Resources Canada, 1989.

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International Program on Chemical Safety. Platinum. Geneva: World Health Organization, 1991.

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Canada. Dept. of Energy, Mines and Resources., ed. Platinum. [Ottawa]: Supply and Services Canada, 1989.

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King, Aliya S. Platinum. New York: Touchstone Books, 2010.

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Larkin, Jason. Platinum. Johannesburg: Fourthwall Books, 2015.

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Likhachev, A. P. Platino-medno-nikelevye i platinovye mestorozhdenii︠a︡ =: Platinum-nickel-copper and platinum deposits. Moskva: Ėslan, 2006.

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Recording Industry Association of America., ed. Gold, platinum, and multi-platinum certifications. Washington, D.C: Recording Industry Association of America, 1989.

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Bernfeld, G. J., A. J. Bird, R. I. Edwards, Hartmut Köpf, Petra Köpf-Maier, Christoph J. Raub, W. A. M. te Riele, Franz Simon, and Walter Westwood. Pt Platinum. Edited by Gary J. K. Acres and Kurt Swars. Berlin, Heidelberg: Springer Berlin Heidelberg, 1985. http://dx.doi.org/10.1007/978-3-662-10278-7.

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Belin, Esther, Yvette Cauchois, Christiane Sénémaud, Jean Blaise, Jean-François Wyart, Helmut Münzel, and Joachim Wagner. Pt Platinum. Edited by Dieter Koschel and Joachim Wagner. Berlin, Heidelberg: Springer Berlin Heidelberg, 1988. http://dx.doi.org/10.1007/978-3-662-09377-1.

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Book chapters on the topic "Platinum"

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Kurtz, Wolfgang, and Hans Vanecek. "Platinum." In W Tungsten, 312–20. Berlin, Heidelberg: Springer Berlin Heidelberg, 1987. http://dx.doi.org/10.1007/978-3-662-08690-2_34.

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Brenan, James M. "Platinum." In Encyclopedia of Earth Sciences Series, 1–3. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-39193-9_228-1.

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Brenan, James M. "Platinum." In Encyclopedia of Earth Sciences Series, 1233–35. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-39312-4_228.

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Lebeau, Alex. "Platinum." In Hamilton & Hardy's Industrial Toxicology, 193–98. Hoboken, New Jersey: John Wiley & Sons, Inc., 2015. http://dx.doi.org/10.1002/9781118834015.ch28.

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Turova, Nataliya. "Platinum." In Inorganic Chemistry in Tables, 110–11. Berlin, Heidelberg: Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-20487-6_43.

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Brookins, Douglas G. "Platinum." In Eh-pH Diagrams for Geochemistry, 88–89. Berlin, Heidelberg: Springer Berlin Heidelberg, 1988. http://dx.doi.org/10.1007/978-3-642-73093-1_34.

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Baker, Ian. "Platinum." In Fifty Materials That Make the World, 153–56. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-78766-4_29.

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Bessarabov, Dmitri. "Platinum." In Encyclopedia of Membranes, 1. Berlin, Heidelberg: Springer Berlin Heidelberg, 2015. http://dx.doi.org/10.1007/978-3-642-40872-4_1085-4.

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Levin, Vuma Ian. "Platinum." In Heavy Metal, 155–56. Cambridge, UK: Open Book Publishers, 2024. http://dx.doi.org/10.11647/obp.0373.19.

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Soled, S., A. Wold, and C. R. Symon. "Platinum Disulfide and Platinum Ditelluride." In Inorganic Syntheses, 49–51. Hoboken, NJ, USA: John Wiley & Sons, Inc., 2007. http://dx.doi.org/10.1002/9780470132500.ch9.

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Conference papers on the topic "Platinum"

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Schulz, Katharina, Daniel Ernst, Siegfried Menzel, Thomas Gemming, Juergen Eckert, and Klaus-Juergen Wolter. "Thermosonic platinum wire bonding on platinum." In 2014 37th ISSE International Spring Seminar in Electronics Technology (ISSE). IEEE, 2014. http://dx.doi.org/10.1109/isse.2014.6887576.

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"Platinum Sponsors." In 2008 IEEE 24th International Conference on Data Engineering. IEEE, 2008. http://dx.doi.org/10.1109/icde.2008.4497402.

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"Platinum sponsor." In 2015 International Conference on Biometrics (ICB). IEEE, 2015. http://dx.doi.org/10.1109/icb.2015.7139117.

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"Platinum sponsor." In 2012 IEEE Asia-Pacific Conference on Applied Electromagnetics (APACE). IEEE, 2012. http://dx.doi.org/10.1109/apace.2012.6457704.

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"Sponsors: Platinum." In 2014 IEEE Asia-Pacific Conference on Applied Electromagnetics (APACE). IEEE, 2014. http://dx.doi.org/10.1109/apace.2014.7043827.

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"Platinum Sponsors." In 2020 IEEE International Conference on Informatics, IoT, and Enabling Technologies (ICIoT). IEEE, 2020. http://dx.doi.org/10.1109/iciot48696.2020.9089627.

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"Platinum sponsorship." In 2010 9th IEEE/IAS International Conference on Industry Applications - INDUSCON 2010. IEEE, 2010. http://dx.doi.org/10.1109/induscon.2010.5739856.

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"Platinum sponsor." In Propagation Conference (LAPC). IEEE, 2011. http://dx.doi.org/10.1109/lapc.2011.6113994.

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"Platinum Sponsor." In 2022 IEEE MTT-S International Conference on Microwave Acoustics and Mechanics (IC-MAM). IEEE, 2022. http://dx.doi.org/10.1109/ic-mam55200.2022.9855358.

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"Platinum sponsor." In 2010 IEEE International Conference on Automation Science and Engineering (CASE 2010). IEEE, 2010. http://dx.doi.org/10.1109/coase.2010.5584340.

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Reports on the topic "Platinum"

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McLeod, C. R., and S. R. Morison. Placer gold, platinum. Natural Resources Canada/ESS/Scientific and Technical Publishing Services, 1995. http://dx.doi.org/10.4095/207950.

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Barrie, C. T. Magmatic platinum group elements. Natural Resources Canada/ESS/Scientific and Technical Publishing Services, 1995. http://dx.doi.org/10.4095/208044.

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Mangum, B. W. Platinum resistance thermometer calibrations. Gaithersburg, MD: National Bureau of Standards, 1987. http://dx.doi.org/10.6028/nbs.sp.250-22.

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Chiang, I., J. Geller, C.-I. Pai, C. Pearson, A. Pendzick, and E. Zitvogel. Water-cooled platinum C target. Office of Scientific and Technical Information (OSTI), March 1998. http://dx.doi.org/10.2172/1157477.

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Eckstrand, O. R. Magmatic nickel-copper-platinum group elements. Natural Resources Canada/ESS/Scientific and Technical Publishing Services, 1995. http://dx.doi.org/10.4095/208040.

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Garrity, K. M., D. C. Ripple, and W. L. Tew. SRM 1967a: High-Purity Platinum Thermoelement. National Institute of Standards and Technology, March 2016. http://dx.doi.org/10.6028/nist.sp.260-183.

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Hulbert, L. J., J. M. Duke, O. R. Eckstrand, J. W. Lydon, R F J. Scoates, L. J. Cabri, and T N Irvine. Geological Environments of the Platinum Group Elements. Natural Resources Canada/ESS/Scientific and Technical Publishing Services, 1988. http://dx.doi.org/10.4095/130338.

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Krebs, L. C., and Takanobu Ishida. Characterization of electrochemically modified polycrystalline platinum surfaces. Office of Scientific and Technical Information (OSTI), December 1991. http://dx.doi.org/10.2172/5974973.

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LaiHing, Kenneth. Third Order Susceptibility of Platinum Sulfide Sol. Fort Belvoir, VA: Defense Technical Information Center, December 1992. http://dx.doi.org/10.21236/ada337943.

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Krebs, Leonard C., and Takanobu Ishida. Characterization of electrochemically modified polycrystalline platinum surfaces. Office of Scientific and Technical Information (OSTI), December 1991. http://dx.doi.org/10.2172/10112590.

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