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1

1946-, Barnes Peter J., Page C. P, and Henson P. M. 1940-, eds. Platelet activating factor and human disease. Oxford: Blackwell Scientific, 1989.

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2

M, Winslow C., and Lee M. L, eds. New horizons in platelet activating factor research. Chichester: Wiley, 1987.

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3

M, Winslow C., and Lee M. L, eds. New horizons in platelet activating factor research. Chichester [West Sussex]: Wiley, 1987.

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4

P, Braquet, ed. CRC handbook of PAF and PAF antagonists. Boca Raton, Fla: CRC Press, 1991.

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5

Snyder, Fred, ed. Platelet-Activating Factor and Related Lipid Mediators. Boston, MA: Springer US, 1987. http://dx.doi.org/10.1007/978-1-4684-5284-6.

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6

Fred, Snyder, ed. Platelet-activating factor and related lipid mediators. New York: Plenum Press, 1987.

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7

K, Nigam S., Kunkel Gert, Prescott Stephen M, and International Congress on Platelet-Activating Factor and Related Lipid Mediators (1995 : Berlin, Germany), eds. Platelet-activating factor and related lipid mediators 2: Roles in health and disease. New York: Plenum Press, 1996.

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8

Nigam, Santosh, Gert Kunkel, and Stephen M. Prescott, eds. Platelet-Activating Factor and Related Lipid Mediators 2. Boston, MA: Springer US, 1996. http://dx.doi.org/10.1007/978-1-4899-0179-8.

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9

A, Handley Dean, ed. Platelet-activating factor in endotoxin and immune diseases. New York: Dekker, 1990.

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10

Pharmacy), Symposium on Problems on PAF (11th 1987 Tohoku College of. Trends in pharmacological research on platelet activating factor (PAF) in Japan: Proceedings of the Symposium on Problems on PAF held at the Tohoku College of Pharmacy, Sendai, Japan, September 19th, 1987. Tokyo: Ishiyaku EuroAmerica, 1988.

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11

Kucey, Daryl Stanton. Modulation of macrophage procoagulant activity by platelet activating factor. Ottawa: National Library of Canada = Bibliothèque nationale du Canada, 1992.

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12

S, Authi Kalwant, Bruchhausen F. von 1929-, and Walter U. 1949-, eds. Platelets and their factors. Berlin: Springer, 1997.

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13

George, Holme, and Morley J, eds. PAF in asthma: Proceedings of a symposium held in Canada in June 1986. London: Academic Press, 1989.

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14

Fondation IPSEN pour la recherche thérapeutique. Meeting. The role of platelet-activating factor in immune disorders: Proceedings of the Meeting of the "Fondation IPSEN pour la recherche thérapeutique", Paris, June 25-26, 1987 (part II). Edited by Braquet P. Basel: Karger, 1988.

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15

Siegel, Andre Clifford. Biosynthetic pathways of platelet-activating factor in the nongolian gerbil model of cerebral ischemia. Ottawa: National Library of Canada, 1996.

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16

C, Murphy Robert, and Fitzpatrick Frank A, eds. Arachidonate related lipid mediators. San Diego: Academic Press, 1990.

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17

1952-, Schmitz-Schumann M., Menz G, and Page C. P, eds. PAF, platelets, and asthma. Basel: Birkhäuser, 1987.

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18

International Washington Spring Symposium (11th 1991 George Washington University). Prostaglandins, leukotrienes, lipoxins, and PAF. New York: Plenum, 1991.

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19

International Washington Spring Symposium (11th 1991 George Washington University). Prostaglandins, leukotrienes, lipoxins, and PAF: Mechanism of action, molecular biology, and clinical applications. New York: Plenum Press, 1991.

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20

1946-, Stute W., and Seminar on Empirical Processes (1985 : Düsseldorf, Germany), eds. Seminar on Empirical Processes. Basel: Birkhäuser Verlag, 1987.

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21

A, Dennis Edward, Hunter Tony 1943-, Berridge Michael J, and University of California, Los Angeles., eds. Cell activation and signal initiation: Receptor and phospholipase control of inositol phosphate, PAF, and eicosanoid production : proceedings of a UCLA symposium held in Keystone, Colorado, April 17-23, 1988. New York: A.R. Liss, 1989.

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22

M, Cunningham Fiona, ed. Lipid mediators. London: Academic Press, 1994.

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23

Schäufele, Andreas. Beeinflussung des Schwellensynergismus menschlicher Thrombozyten auf Platelet Activating Factor (PAF) und Collagen im plättchenreichen Plasma nach inhalativer Provokation mit Lysin-Acetyl-Salicyl-Säure. [s.l.]: [s.n.], 1988.

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24

Braquet. Platelet-activating Factor Cell Immuno. Karger, 1988.

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25

Platelet-Activating Factor Acetylhydrolases (PAF-AH). Elsevier, 2015. http://dx.doi.org/10.1016/s1874-6047(15)x0003-5.

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26

Tamanoi, Fuyuhiko, Diana Stafforini, and Keizo Inoue. Platelet-Activating Factor Acetylhydrolases (PAF-AH). Elsevier Science & Technology Books, 2015.

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27

Snyder, F. Platelet-Activating Factor and Related Lipid Mediators. Springer, 2012.

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28

Snyder, F. Platelet-Activating Factor and Related Lipid Mediators. Springer London, Limited, 2013.

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29

(Editor), C. P. Page, P. Barnes (Editor), and P. Henson (Editor), eds. Platelet Activating Factor & Human Disease, Frontiers in Pharmacology & Therapeutics. Blackwell Science, 1989.

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30

Platelet activating factor receptor: Signal mechanisms and molecular biology. Boca Raton, Fla: CRC Press, 1993.

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31

Braquet, Pierre. Handbook of PAF and PAF Antagonist. CRC-Press, 1991.

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32

1946-, Barnes P. J., Page Clive P, and Henson P. M. 1940-, eds. Plateletactivating factor and human disease. Blackwell Scientific, 1989.

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33

Baumann, Wolfgang J. Platelet-Activating Factor and Structurally Related Alkyl Ether Lipids. Amer Oil Chemists Society, 1991.

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34

Wolfgang/Bauman. Platelet-Activating Factor and Structurally Related Alkyl Ehter Lipids. Other, 1992.

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35

O'Flaherty, Joseph T., and Peter W. Ramwell. Paf Antagonists: New Developments for Clinical Application (Advances in Applied Biotechnology Series, Vol 9). Portfolio Pub Co, 1991.

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36

G, Holme, and Morley J. 1938-, eds. PAF in asthma. Academic Press, 1989.

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37

Ogura, Yasumi. Trends in Pharmacological Research on Platelet Activating Factor (Paf in Japan). Medico Dental Media International, 1988.

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38

Multiple organ dysfunction syndrome: Examining the role of eicosanoids and procoagulants. New York: Chapman & Hall, 1996.

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39

Platelet-Activating Factor and Cell Immunology (New Trends in Lipid Mediators Research). S. Karger AG (Switzerland), 1988.

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40

Nigam, Santosh, Stephen M. Prescott, and Gert Kunkel. Platelet-Activating Factor and Related Lipid Mediators 2: Roles in Health and Disease. Springer, 2013.

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41

Nigam, Santosh, Stephen M. Prescott, and Gert Kunkel. Platelet-Activating Factor and Related Lipid Mediators 2: Roles in Health and Disease. Springer London, Limited, 2013.

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42

Shukla, Shivendra D. Platelet Activating Factor Receptor: Signal Mechanisms and Molecular Biology (Handbooks in Pharmacology and Toxicology). CRC, 1992.

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43

Multiple Organ Dysfunction Syndrome: Examining the Role of Eicosanoids and Procoagulants (Medical Intelligence Unit). Landes Bioscience, 1996.

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44

Williams, J. G. Multiple Organ Dysfunction Syndrome: Examining the Role of Eicosanoids and Procoagulants (Medical Intelligence Unit). Springer, 1996.

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45

Arachidonate Related Lipid Mediators, Volume 187: Volume 187: Arachidonate Related Lipid Mediators (Methods in Enzymology). Academic Press, 1990.

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46

Abelson, John N., Robert C. Murphy, Melvin I. Simon, and Frank A. Fitzpatrick. Arachidonate Related Lipid Mediators. Elsevier Science & Technology Books, 1990.

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47

Raschke, Petra. Zu den kardiovaskulären Wirkungen von Platelet-Activating Factor (PAF) beimMeerschweinchen: Antagonisierung von PAF durch ein Triazolodiazepin (WEB 2086). 1988.

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48

(Editor), Santosh Nigam, Gert Kunkel (Editor), and Stephen M. Prescott (Editor), eds. Platelet-Activating Factor and Related Lipid Mediators 2: Roles in Health and Disease (Advances in Experimental Medicine and Biology). Springer, 1997.

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49

Cunningham, Fiona M. Lipid Mediators (The Handbook of Immunopharmacology). Academic Pr, 1993.

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50

Curry, Nicola, and Raza Alikhan. Normal platelet function. Edited by Patrick Davey and David Sprigings. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199568741.003.0281.

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Abstract:
The platelet is a small (2–4 µm in diameter), discoid, anucleate cell that circulates in the blood. In health, it plays a vital role in haemostasis, and in disease it contributes to disorders of bleeding and thrombosis. Platelets are produced from the surface of megakaryocytes in the bone marrow, under tight homeostatic control regulated by the cytokine thrombopoietin. Platelets have a lifespan of approximately 7–10 days, and usually circulate in the blood stream in a quiescent state. Intact, undamaged vessel walls help to maintain platelets in this inactive state by releasing nitric oxide, which acts both to dilate the vessel wall and to inhibit platelet adhesion, activation, and aggregation. After trauma to the blood vessel wall, platelets are activated and, acting in concert with the endothelium and coagulation factors, form a stable clot. This chapter addresses platelet structure and function, and the response of platelets to vessel injury.
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