Academic literature on the topic 'Plasma membrane signaling'
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Journal articles on the topic "Plasma membrane signaling"
Wang, Nan, Marijke De Bock, Elke Decrock, Mélissa Bol, Ashish Gadicherla, Mathieu Vinken, Vera Rogiers, Feliksas F. Bukauskas, Geert Bultynck, and Luc Leybaert. "Paracrine signaling through plasma membrane hemichannels." Biochimica et Biophysica Acta (BBA) - Biomembranes 1828, no. 1 (January 2013): 35–50. http://dx.doi.org/10.1016/j.bbamem.2012.07.002.
Full textChavan, Tanmay Sanjeev, Serena Muratcioglu, Richard Marszalek, Hyunbum Jang, Ozlem Keskin, Attila Gursoy, Ruth Nussinov, and Vadim Gaponenko. "Plasma membrane regulates Ras signaling networks." Cellular Logistics 5, no. 4 (October 2, 2015): e1136374. http://dx.doi.org/10.1080/21592799.2015.1136374.
Full textGrecco, Hernán E., Malte Schmick, and Philippe I. H. Bastiaens. "Signaling from the Living Plasma Membrane." Cell 144, no. 6 (March 2011): 897–909. http://dx.doi.org/10.1016/j.cell.2011.01.029.
Full textFröhlich, Florian, Karen Moreira, Pablo S. Aguilar, Nina C. Hubner, Matthias Mann, Peter Walter, and Tobias C. Walther. "A genome-wide screen for genes affecting eisosomes reveals Nce102 function in sphingolipid signaling." Journal of Cell Biology 185, no. 7 (June 29, 2009): 1227–42. http://dx.doi.org/10.1083/jcb.200811081.
Full textFoley, John F. "Revealing the plasma membrane in GPCR signaling." Science Signaling 13, no. 636 (June 16, 2020): eabd3019. http://dx.doi.org/10.1126/scisignal.abd3019.
Full textCorre, Isabelle, Colin Niaudet, and Francois Paris. "Plasma membrane signaling induced by ionizing radiation." Mutation Research/Reviews in Mutation Research 704, no. 1-3 (April 2010): 61–67. http://dx.doi.org/10.1016/j.mrrev.2010.01.014.
Full textBaird, Barbara. "Plasma Membrane Heterogeneity and Receptor Mediated Signaling." Biophysical Journal 98, no. 3 (January 2010): 2a. http://dx.doi.org/10.1016/j.bpj.2009.12.007.
Full textAbbas, Wasim, and Georges Herbein. "Plasma membrane signaling in HIV-1 infection." Biochimica et Biophysica Acta (BBA) - Biomembranes 1838, no. 4 (April 2014): 1132–42. http://dx.doi.org/10.1016/j.bbamem.2013.06.020.
Full textWills, Rachel C., and Gerald R. V. Hammond. "PI(4,5)P2: signaling the plasma membrane." Biochemical Journal 479, no. 21 (November 11, 2022): 2311–25. http://dx.doi.org/10.1042/bcj20220445.
Full textAnde, Sudharsana Rao, and Suresh Mishra. "Palmitoylation of prohibitin at cysteine 69 facilitates its membrane translocation and interaction with Eps 15 homology domain protein 2 (EHD2)." Biochemistry and Cell Biology 88, no. 3 (June 2010): 553–58. http://dx.doi.org/10.1139/o09-177.
Full textDissertations / Theses on the topic "Plasma membrane signaling"
Alenkvist, Ida. "Epac2 signaling at the β-cell plasma membrane." Doctoral thesis, Uppsala universitet, Institutionen för medicinsk cellbiologi, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-284638.
Full textMahammad, Saleemulla. "Cholesterol in T cells homeostasis, plasma membrane organization and signaling /." Doctoral thesis, Stockholm : The Wenner-Gren Institute, Stockholm University, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-38357.
Full textAt the time of the doctoral defense, the following paper was unpublished and had a status as follows: Paper 2: Manuscript. Paper 3: In press.
Takahashi, Satoe. "Plasma Membrane Localization of Signaling Proteins in Yeast: a Dissertation." eScholarship@UMMS, 2008. https://escholarship.umassmed.edu/gsbs_diss/364.
Full textMichael, James. "Regulation of Ras signaling and oncogenesis by plasma membrane microdomains." Diss., Temple University Libraries, 2016. http://cdm16002.contentdm.oclc.org/cdm/ref/collection/p245801coll10/id/377230.
Full textPh.D.
In this study, we assessed the contributions of plasma membrane (PM) microdomain targeting to the functions of H-Ras and R-Ras. These paralogues have identical effector-binding regions, but variant C-terminal targeting domains (tDs) which are responsible for lateral microdomain distribution: activated H-Ras targets to lipid ordered/disordered (Lo/Ld) domain borders, and R-Ras to Lo domains (rafts). We hypothesized that PM distribution regulates Ras effector interactions and downstream signaling. We used tD swap mutants, and assessed effects on signal transduction, cell proliferation, transformation, and tumorigenesis. R-Ras harboring the H-Ras tD (R-Ras-tH) interacted with Raf, and induced Raf and ERK phosphorylation similar to H-Ras. R-Ras-tH stimulated proliferation and transformation in vitro, and these effects were blocked by both MEK and PI3K inhibition. Conversely, the R-Ras tD suppressed H-Ras-mediated Raf activation and ERK phosphorylation, proliferation, and transformation. Thus, Ras access to Raf at the PM is sufficient for MAPK activation and is a principal component of Ras mitogenesis and transformation. Fusion of the R-Ras extended N-terminal domain to H-Ras had no effect on proliferation, but inhibited transformation and tumor progression, indicating that the R-Ras N-terminus also contributes negative regulation to these Ras functions. PI3K activation was tD-independent; however, H-Ras was a stronger activator of PI3K than R-Ras, with either tD. PI3K inhibition nearly ablated transformation by R-Ras-tH, H-Ras, and H-Ras-tR, whereas MEK inhibition had a modest effect on Ras-tH-driven transformation but no effect on H-Ras-tR transformation. R-Ras-tH supported tumor initiation, but not tumor progression. Whereas H-Ras-tR-induced transformation was reduced relative to H-Ras, tumor progression was robust and similar to H-Ras. H-Ras tumor growth was moderately suppressed by MEK inhibition, which had no effect on H-Ras-tR tumor growth. In contrast, PI3K inhibition markedly suppressed tumor growth by H-Ras and H-Ras-tR, indicating that sustained PI3K signaling is a critical pathway for H-Ras-driven tumor progression, independent of microdomains. In the second phase of the study, we investigated the combinatorial use of two drugs currently either in active use as anti-cancer agents (Rapamycin) or in clinical trials (OTX008), as a novel strategy to inhibit H-Ras-driven tumor progression. H-Ras anchored to the plasma membrane shuttles from the lipid ordered (Lo) domain to the lipid ordered/lipid disordered border upon activation, and retention of H-Ras at these sites requires Galectin-1 (Gal-1). We have previously found that genetically-mediated Lo sequestration of H-Ras inhibited MAPK signaling but not PI3K activation. Here we show that inhibition of Gal-1 with OTX008 sequestered H-Ras in the Lo domain, blocked H-Ras-mediated MAPK signaling, and attenuated H-Ras-driven tumor progression in mice. H-Ras-driven tumor growth was also attenuated by treatment with mTOR inhibitor Rapamycin, and this effect was further enhanced in tumors driven by Lo-sequestered H-Ras. These drugs also revealed bidirectional cross-talk in H-Ras pathways. Moreover, dual pathway inhibition with OTX008 and Rapamycin resulted in nearly complete ablation of H-Ras-driven tumor growth. These findings indicate that membrane microdomain sequestration of H-Ras with OTX008, coupled with mTOR inhibition, may support a novel therapeutic approach to treat H-Ras mutant cancers.
Temple University--Theses
Fröhlich, Florian. "Analysis of sphingolipid-signaling at the plasma membrane of Saccharomyces cerevisiae." Diss., lmu, 2010. http://nbn-resolving.de/urn:nbn:de:bvb:19-120516.
Full textWang, Xing. "The locations and signaling of H-Ras on endosomes and plasma membrane." [Ames, Iowa : Iowa State University], 2008.
Find full textDinic, Jelena. "Plasma membrane order; the role of cholesterol and links to actin filaments." Doctoral thesis, Stockholms universitet, Wenner-Grens institut, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-62279.
Full textAt the time of the doctoral defense, the following papers were unpublished and had a status as follows: Paper 2: Submitted. Paper 4: Manuscript.
Lam, Jonathan Lam. "Identification of mammalian cell signaling in response to plasma membrane perforation: Endocytosis of Listeria monocytogenes and The Repair Machinery." The Ohio State University, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=osu1543497502225763.
Full textGouguet, Paul. "Deciphering the proteic partners of REMORIN, a membrane-raft phosphoprotein implicated in plant cell-to-cell communication." Thesis, Bordeaux, 2018. http://www.theses.fr/2018BORD0418.
Full textGroup 1 REMORINs are plant-specific proteins located at the plasma membrane. We have shown that StREM1.3 (REM) is a marker of lipid rafts, plasma membrane domains enriched in sterols and sphingolipids. In addition, REM is enriched in plasmodesmata channels (PD) which are anchored within the cell wall and enable intercellular communication between virtually all plant cells. We have demonstrated for the first time the physiological role of REM in plants, this protein is able to reduce the viral cell-to-cell movement of Potato Virus X (PVX) and other viruses. Moreover, the antiviral activity of REM is regulated by phosphorylation and leads to a modification of the pore size of PD via the accumulation of callose, a sugar polymer, around the neck regions of PD. In order to understand how REM is able to induce the accumulation of callose in these specific regions, a large set of proteins have been selected and the deciphering of their functions have been initiated in planta by transgenic approaches, in transient expression and on transgenic plants, which will be subjected to viral infections to study the spread of viruses. Protein interaction, biochemistry and imaging approaches were also used to study this question. This thesis aims at understanding the mechanisms of the REM interaction with its membrane partners during viral infection, focusing on the protein-protein interactions during the response to PVX. We will focus more particularly on PD proteins and membrane rafts that are most likely targeted during this interaction with viruses
LUNGHI, GIULIA. "GM1 OLIGOSACCHARIDE MODULATION OF CALCIUM SIGNALLING IN NEURONAL FUNCTIONS." Doctoral thesis, Università degli Studi di Milano, 2020. http://hdl.handle.net/2434/792078.
Full textBooks on the topic "Plasma membrane signaling"
Ozhan, Gunes, Erdinc Sezgin, and Anming Meng. Wnt Signaling at the Plasma Membrane: Activation, Regulation and Disease Connection. Frontier Media SA, 2021. http://dx.doi.org/10.3389/978-2-88971-880-1.
Full textPlant signalling, plasma membrane, and change of state. [Geneva]: Laboratory of Plant Physiology, University of Geneva, 1991.
Find full textBook chapters on the topic "Plasma membrane signaling"
Donato, Dominique M., Steven K. Hanks, Kenneth A. Jacobson, M. P. Suresh Jayasekara, Zhan-Guo Gao, Francesca Deflorian, John Papaconstantinou, et al. "Plasma Membrane Ca2+ ATPase." In Encyclopedia of Signaling Molecules, 1439. New York, NY: Springer New York, 2012. http://dx.doi.org/10.1007/978-1-4419-0461-4_101059.
Full textDonato, Dominique M., Steven K. Hanks, Kenneth A. Jacobson, M. P. Suresh Jayasekara, Zhan-Guo Gao, Francesca Deflorian, John Papaconstantinou, et al. "Plasma Membrane Ca2+ Pump." In Encyclopedia of Signaling Molecules, 1439. New York, NY: Springer New York, 2012. http://dx.doi.org/10.1007/978-1-4419-0461-4_101060.
Full textLee, Jung-Youn, Sung Ki Cho, and Ross Sager. "Plasmodesmata and Noncell Autonomous Signaling in Plants." In The Plant Plasma Membrane, 87–107. Berlin, Heidelberg: Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-642-13431-9_4.
Full textStrehler, Emanuel E. "Plasma Membrane Calcium-Transporting ATPase." In Encyclopedia of Signaling Molecules, 4047–54. Cham: Springer International Publishing, 2018. http://dx.doi.org/10.1007/978-3-319-67199-4_133.
Full textStrehler, Emanuel E. "Plasma Membrane Calcium-Transporting ATPase." In Encyclopedia of Signaling Molecules, 1–8. New York, NY: Springer New York, 2016. http://dx.doi.org/10.1007/978-1-4614-6438-9_133-1.
Full textDonato, Dominique M., Steven K. Hanks, Kenneth A. Jacobson, M. P. Suresh Jayasekara, Zhan-Guo Gao, Francesca Deflorian, John Papaconstantinou, et al. "Plasma Membrane Calcium-Transporting ATPase." In Encyclopedia of Signaling Molecules, 1440–46. New York, NY: Springer New York, 2012. http://dx.doi.org/10.1007/978-1-4419-0461-4_133.
Full textIm, Yang Ju, Ingo Heilmann, and Imara Y. Perera. "The Hull of Fame: Lipid Signaling in the Plasma Membrane." In The Plant Plasma Membrane, 437–55. Berlin, Heidelberg: Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-642-13431-9_20.
Full textZamir, Eli, Nachiket Vartak, and Philippe I. H. Bastiaens. "Oncogenic Signaling from the Plasma Membrane." In Vesicle Trafficking in Cancer, 57–74. New York, NY: Springer New York, 2013. http://dx.doi.org/10.1007/978-1-4614-6528-7_3.
Full textDyachok, Oleg, Yunjian Xu, Olof Idevall-Hagren, and Anders Tengholm. "Fluorescent Translocation Reporters for Sub–plasma Membrane cAMP Imaging." In cAMP Signaling, 319–38. New York, NY: Springer US, 2022. http://dx.doi.org/10.1007/978-1-0716-2245-2_20.
Full textTengholm, Anders, and Olof Idevall-Hagren. "Imaging Sub-plasma Membrane cAMP Dynamics with Fluorescent Translocation Reporters." In cAMP Signaling, 85–101. New York, NY: Springer New York, 2015. http://dx.doi.org/10.1007/978-1-4939-2537-7_7.
Full textConference papers on the topic "Plasma membrane signaling"
Lee, Donghee, Jeonghoon Lee, Choonho Park, and Jung Kyung Kim. "Simultaneous Measurements of Diffusion Coefficient on Cell Membrane by Fluorescence Photobleaching and Single Quantum Dot Tracking Techniques." In ASME 2010 First Global Congress on NanoEngineering for Medicine and Biology. ASMEDC, 2010. http://dx.doi.org/10.1115/nemb2010-13027.
Full textBaird, Barbara A., Nirmalya Bag, and David A. Holowka. "Dynamically heterogeneous plasma membrane is poised for initiation of receptor-mediated mast cell signaling." In Multiphoton Microscopy in the Biomedical Sciences XXII, edited by Ammasi Periasamy, Peter T. So, and Karsten König. SPIE, 2022. http://dx.doi.org/10.1117/12.2613064.
Full textBarbee, Kenneth A., Gulyeter Serbest, and Joel Horwitz. "Membrane Integrity as a Therapeutic Target in Neural Cell Injury." In ASME 2004 International Mechanical Engineering Congress and Exposition. ASMEDC, 2004. http://dx.doi.org/10.1115/imece2004-61566.
Full textHelfield, Brandon, Xucai Chen, Simon Watkins, and Flordeliza Villanueva. "Notice of Removal: Insight into the plasma membrane resealing and calcium signaling dynamics of sonoporation." In 2017 IEEE International Ultrasonics Symposium (IUS). IEEE, 2017. http://dx.doi.org/10.1109/ultsym.2017.8092598.
Full textNganga, Rose. "Abstract 4298: FTY720 induces necroptosis in lung cancer by modulating ceramide signaling at the plasma membrane." In Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.am2017-4298.
Full textAbraham, Adam C., Megan L. Killian, Roger C. Haut, and Tammy L. Haut Donahue. "Long Term Effect of P188 on Meniscus Preservation Following Blunt Trauma." In ASME 2012 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2012. http://dx.doi.org/10.1115/sbc2012-80775.
Full textMichael, James, Jeremy G. T. Wurtzel, and Lawrence E. Goldfinger. "Abstract 4036: Palmitoylated Ras-driven MAPK signaling, transformation and tumorigenesis, but not tumor progression, are spatially regulated by plasma membrane microdomains." In Proceedings: AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA. American Association for Cancer Research, 2015. http://dx.doi.org/10.1158/1538-7445.am2015-4036.
Full textQian, David, Jinyoung Byun, Xiangjun Xiao, Stephanie Her, Arief Suriawinata, Christopher Amos, and Richard Barth. "Abstract 2233: PI3K/Akt/mTOR signaling and plasma membrane proteins are implicated in responsiveness to adjuvant dendritic cell vaccination for metastatic colorectal cancer." In Proceedings: AACR 107th Annual Meeting 2016; April 16-20, 2016; New Orleans, LA. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/1538-7445.am2016-2233.
Full textMoran, Emma C., Pedro M. Baptista, Kenichiro Nishii, David Wasnick, Shay Soker, and Jessica L. Sparks. "Expression of Primary Cilia on Liver Stem and Progenitor Cells: Potential Role for Mechanosensing in Liver Development." In ASME 2013 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/sbc2013-14122.
Full textFrancke, Eric, Michelle K. Elfervig, Ajay Sood, Thomas D. Brown, Donald K. Bynum, and Albert J. Banes. "Fluid-Induced Shear Stress Stimulates Ca2+ Signaling in Human Tendon Epitenon Cells." In ASME 1999 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 1999. http://dx.doi.org/10.1115/imece1999-0401.
Full textReports on the topic "Plasma membrane signaling"
Yalovsky, Shaul, and Julian Schroeder. The function of protein farnesylation in early events of ABA signal transduction in stomatal guard cells of Arabidopsis. United States Department of Agriculture, January 2002. http://dx.doi.org/10.32747/2002.7695873.bard.
Full textPhilosoph-Hadas, Sonia, Peter B. Kaufman, Shimon Meir, and Abraham H. Halevy. Inhibition of the Gravitropic Shoot Bending in Stored Cut Flowers Through Control of Their Graviperception: Involvement of the Cytoskeleton and Cytosolic Calcium. United States Department of Agriculture, December 2005. http://dx.doi.org/10.32747/2005.7586533.bard.
Full textDelmer, Deborah P., Douglas Johnson, and Alex Levine. The Role of Small Signal Transducing Gtpases in the Regulation of Cell Wall Deposition Patterns in Plants. United States Department of Agriculture, August 1995. http://dx.doi.org/10.32747/1995.7570571.bard.
Full textAvni, Adi, and Gitta L. Coaker. Proteomic investigation of a tomato receptor like protein recognizing fungal pathogens. United States Department of Agriculture, January 2015. http://dx.doi.org/10.32747/2015.7600030.bard.
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