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Dissertations / Theses on the topic 'Plant autophagy'

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1

Ballhaus, Florentine. "Investigating plant autophagy with new chemical modulators." Thesis, Uppsala universitet, Institutionen för biologisk grundutbildning, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-428075.

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Autophagy is a major catabolic pathway in which cell components get sequestered in a double membrane vesicle, transported to the vacuole, degraded by vacuolar hydrolases and recycled.  Through this process, cells ensure cell homeostasis and remobilise nutrients. The autophagic flux can be enhanced as an adaptive stress response, improving plants resistance against stress, reducing aging and ultimately increasing yield. However, autophagy regulation in plants remains poorly understood.  Novel plant-specific modulators can be used in a chemical genetic approach for identification of proteins inv
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Testi, Serena. "L’effecteur Avh195 de Phytophthora parasitica : antagoniste de l’autophagie chez l’hôte et promoteur du processus infectieux." Electronic Thesis or Diss., Université Côte d'Azur (ComUE), 2018. http://theses.univ-cotedazur.fr/2018AZUR4087.

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L’agent pathogène Phytophthora parasitica est un oomycète qui a des effets dévastateurs sur l’agriculture et les écosystèmes naturels. En tant qu'organisme hémi-biotrophe, il infecte les racines des plantes en établissant d'abord un contact intime avec les cellules hôtes (biotrophie) avant de les tuer (nécrotrophie) et de terminer son cycle d'infection. Pour contrôler ces processus, les oomycètes sécrètent des protéines effectrices, qui sont internalisées dans les cellules végétales par un motif de translocation (appelé RxLR-EER) pour manipuler la physiologie et les réponses immunitaires de l'
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3

Gomez, Rodrigo Enrique. "Unravelling the contribution of lipids in plant autophagy : Identification and functional characterization of lipids implicated in the autophagic process in Arabidopsis." Thesis, Bordeaux, 2021. http://www.theses.fr/2021BORD0103.

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Les plantes, étant des organismes sessiles, sont fréquemment confrontées à une grande variété de stress environnementaux. Ces conditions peuvent conduire à l'accumulation d'agrégats de protéines ou au disfonctionnement de multiples organites intracellulaires. Pour faire face à ces conditions, les plantes ont mis au point des mécanismes d'adaptation sophistiqués qui permettent le recyclage des composants intracellulaires. Ces mécanismes sont essentiels pour les remodelages métaboliques nécessaires à un recyclage efficace des nutriments ainsi qu'à l'élimination des composants nocifs pour la cell
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4

Testi, Serena. "L’effecteur Avh195 de Phytophthora parasitica : antagoniste de l’autophagie chez l’hôte et promoteur du processus infectieux." Thesis, Université Côte d'Azur (ComUE), 2018. http://www.theses.fr/2018AZUR4087/document.

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L’agent pathogène Phytophthora parasitica est un oomycète qui a des effets dévastateurs sur l’agriculture et les écosystèmes naturels. En tant qu'organisme hémi-biotrophe, il infecte les racines des plantes en établissant d'abord un contact intime avec les cellules hôtes (biotrophie) avant de les tuer (nécrotrophie) et de terminer son cycle d'infection. Pour contrôler ces processus, les oomycètes sécrètent des protéines effectrices, qui sont internalisées dans les cellules végétales par un motif de translocation (appelé RxLR-EER) pour manipuler la physiologie et les réponses immunitaires de l'
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5

Fancy, Nurun Nahar. "Role of S-nitrosylation in plant salt stress." Thesis, University of Edinburgh, 2017. http://hdl.handle.net/1842/29509.

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Salinity stress is one of the main challenges for crop growth and production. The estimated loss of crop yield due to salinity stress is up to 20% worldwide each year. Plants have evolved an array of mechanisms to defend themselves against salinity stress. A key aspect of plant responses to salinity stress is the engagement of a nitrosative burst that results in nitric oxide (NO) accumulation. A major mechanism for the transfer of NO bioactivity is S-nitrosylation which is a modification of the reactive thiol group of a rare but highly active cysteine residue within a protein through the addit
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6

Sumita, Takuya. "Studies on intracellular protein degradation pathways in plant fungal pathogens." Kyoto University, 2019. http://hdl.handle.net/2433/242706.

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Kyoto University (京都大学)<br>0048<br>新制・課程博士<br>博士(農学)<br>甲第21829号<br>農博第2342号<br>新制||農||1068(附属図書館)<br>学位論文||H31||N5201(農学部図書室)<br>京都大学大学院農学研究科地域環境科学専攻<br>(主査)教授 田中 千尋, 教授 本田 与一, 准教授 刑部 正博<br>学位規則第4条第1項該当
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7

Puleston, Daniel. "The role of autophagy in CD8plus T cell immunity." Thesis, University of Oxford, 2015. http://ora.ox.ac.uk/objects/uuid:6cc5b853-4899-4de2-8924-71f7ee0659a1.

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8

Okemo, Pauline Asami. "Regulation of plant programmed cell death by energy metabolism in the Australian resurrection grass Tripogon loliiformis." Thesis, Queensland University of Technology, 2020. https://eprints.qut.edu.au/205617/1/Pauline_Okemo_Thesis.pdf.

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Recent studies have shown that T.loliiformis, a resurrection grass, may use the tight regulation of PCD pathways like autophagy to facilitate desiccation tolerance. The aim of this project was to further investigate the mechanisms that T.loliiformis use to suppress PCD and survive prolonged periods of water deficit. This study provides additional insight on how T.loliiformis attains desiccation tolerance that significantly contributes to our knowledge on the pathways and mechanisms used by resurrection plants. The findings from this study will hopefully be employed to harness drought tolerant
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9

Zhang, Zhu. "Exploration of the anticancer mechanisms of novel chemotherapeutic adjuvants involving autophagy and immune system reprogramming in the treatment of pancreatic cancer." HKBU Institutional Repository, 2020. https://repository.hkbu.edu.hk/etd_oa/755.

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Pancreatic cancer is known to be one of the most life-threatening cancers characterized by aggressive local invasion and distant metastasis. The high basal level of autophagy in pancreatic cancer may be responsible for the low chemotherapeutic drug response rate and poor disease prognosis. However, the clinical application of autophagy inhibitors was unsatisfactory due to their toxicity and minimal single-agent anticancer efficacy. Hence, oncologists begin to consider the tumor microenvironment when exploring new drug targets. In the present study, the anti-tumorigenic mechanisms of two major
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10

Milani, Manuela. "Cell stress response and hypoxia in breast cancer." Thesis, University of Oxford, 2011. http://ora.ox.ac.uk/objects/uuid:74d3bf91-9888-4e9e-b5e1-7d5d2d476174.

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During severe hypoxia (<0.01% oxygen) the protein folding machinery becomes dysfunctional, resulting in the accumulation of unfolded proteins with consequent endoplasmic reticulum (ER) stress and activation of the unfolded protein response (UPR) and autophagy, a process involved in the physiological turnover of cytoplasmic components. The link between the UPR and autophagy is not clearly defined. The aim of this thesis is to investigate the role of the induction of UPR under severe hypoxia in tumour survival and resistance to therapy. The results of this research suggest that the activating tr
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11

Njaci, Isaac. "The role of MicroRNAs in stress response in the resurrection plant Tripogon loliiformis." Thesis, Queensland University of Technology, 2016. https://eprints.qut.edu.au/93740/1/Isaac_Njaci_Thesis.pdf.

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Research in this thesis focussed on the improvement of agricultural crops in increasing water use efficiency that impacts global crop productivity. The study identified key genetic regulatory mechanisms that the resurrection plant Tripogon loliiformis utilises to tolerate desiccation. Due to the conserved nature of the pathways involved, this information can be transferred for the enhancement of drought tolerance and water use efficiency in agricultural crops. Specifically this study used high throughput sequencing, microscopy and plant transformation to further the understanding of post-tr
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12

La, Spina Martina. "Pharmacology, biochemistry and biomedical applications of plant stilbenes." Doctoral thesis, Università degli studi di Padova, 2017. http://hdl.handle.net/11577/3423240.

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This thesis reports the research I conducted on aspects of the pharmacology and biological activities of two natural stilbenes, Resveratrol (Rv) and Pterostilbene (Pt), major polyphenolic components of grapevines and blueberries respectively. Over the years, these two molecules have drawn attention from the scientific community thanks to their beneficial bioactivities, relevant for many areas of health care. Numerous papers describe their protective roles against the metabolic syndrome, cancer development and neurodegeneration. These striking effects nowadays are not exclusively attribu
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13

Escamez, Sacha. "Xylem cells cooperate in the control of lignification and cell death during plant vascular development." Doctoral thesis, Umeå universitet, Institutionen för fysiologisk botanik, 2016. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-115787.

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The evolutionary success of land plants was fostered by the acquisition of the xylem vascular tissue which conducts water and minerals upwards from the roots. The xylem tissue of flowering plants is composed of three main types of cells: the sap-conducting tracheary elements (TE), the fibres which provide mechanical support and the parenchyma cells which provide metabolic support to the tissue. Both the TEs and the fibres deposit thick polysaccharidic secondary cell walls (SCWs), reinforced by a rigid phenolic polymer called lignin. The cell walls of TEs form efficient water conducting hollow
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14

Karbaschi, Mohammad Reza. "Structural, physiological and molecular characterisation of the Australian native resurrection grass Tripogon loliiformis (F.Meull) C.E.Hubb during dehydration and rehydration." Thesis, Queensland University of Technology, 2015. https://eprints.qut.edu.au/90050/1/Mohammad%20Reza_Karbaschi_Thesis.pdf.

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There is an urgent need to develop crops that can withstand future climates. Results from this thesis demonstrated that a native Australian resurrection grass exhibits structural, physiological and metabolic strategies to tolerate drying. These strategies may be utilized for the generation of stress tolerant crops.
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15

Zayer, Adam. "Cellular models for characterisation of MINA53, a 2-oxoglutarate-dependent dioxygenase." Thesis, University of Oxford, 2012. http://ora.ox.ac.uk/objects/uuid:ebd1dfcd-0c8e-4c87-9644-8ddfd9208456.

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2-0xoglutarate/Fe(II)-dependent dioxygenases (ZOG Oxygenases) are a relatively poorly characterised enzyme family that hydroxylate biological macromolecules to regulate a variety of essential cellular processes in mammals, including; chromatin remodeling, extra-cellular matrix formation and oxygen sensing. The work in this th esis focuses on a ZOG Oxygenase termed Myc-Induced Nuclear Antigen (MINAS3). This enzyme has been implicated in ribosome biogenesis and cell proliferation, and observed overexpressed in several tumour types, yet the identity afits substrate(s) and their role in cancer is
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16

Broderick, Shaun Robert. "Pollination-Induced Gene Changes That Lead to Senescence in Petunia × hybrida." The Ohio State University, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=osu1408958432.

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17

Chen, Qinwu. "Role of autophagy in nitrogen remobilization and adaptation to environment in plants." Thesis, Université Paris-Saclay (ComUE), 2019. http://www.theses.fr/2019SACLS230.

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L'autophagie est importante pour le recyclage et la mobilisation des éléments nutritifs dans les plantes. Plusieurs lignées sur-exprimant les gènes AtATG8a-i d’Arabidopsis ont été sélectionnées afin de déterminer l'effet de l'augmentation de l'activité autophagique sur l'efficacité de la remobilisation de l'azote. Les lignées sur-expresseur ont présenté une meilleure remobilisation de l'azote des feuilles de la rosette jusqu'aux graines qque le contrôle, mais uniquement dans des conditions de culture en nitrate pléthorique. Les lignées sur-exprimant ATG8a et ATG8g ont été les plus performantes
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18

Chen, Leilei. "The molecular mechanism of Chinese medicine Uncaria Rhynchophylla (gouteng) for inducing autophagy and protecting neurons in Parkinson's disease." HKBU Institutional Repository, 2015. https://repository.hkbu.edu.hk/etd_oa/204.

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Parkinson’s disease (PD) is the second most common neurodegenerative disorder characterized by the accumulation of protein aggregates (namely Lewy bodies) in dopaminergic neurons in the substantia nigra region of the brain. Alpha-synuclein (α- syn) is the major component of Lewy bodies (LBs) in PD, and impairment of the autophagy-lysosomal pathway has been linked to its accumulation. In our previous study, we identified corynoxine B (Cory B), an oxindole alkaloid isolated from Uncaria rhynchophylla (Miq.) Jacks (Gouteng in Chinese), as a Beclin-1-dependent autophagy enhancer. In this work, we
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19

Krupař, Pavel. "Úloha lipidů a enzymů metabolizujících lipidy v procesu autofagie u rostlin." Master's thesis, 2021. http://www.nusl.cz/ntk/nusl-446015.

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Plant autophagy is a crucial evolutionary conserved process for recycling cytoplasmic material under stress conditions or during development. The autophagic pathway is negatively regulated by TOR kinase, a versatile molecule modulating a wide range of cellular processes. In mammals, TOR kinase may be activated by phosphatidic acid, a vital signalling lipid. This thesis aims to prove the possible involvement of phospholipids in plant autophagy. I analysed the rate of primary root inhibition in knock-out mutants coding phospholipases in A. thaliana with induced autophagy, measured activity of li
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20

VASARRI, MARZIA. "Biochemical investigation on the bioactive properties of the Posidonia oceanica (L.) Delile marine plant." Doctoral thesis, 2021. http://hdl.handle.net/2158/1235961.

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Posidonia oceanica (L.) Delile is an endemic marine plant of the Mediterranean Sea of great ecological importance. Although the literature tells of a millennial relationship between P. oceanica and humans and despite the tradition has handed down the use of this seagrass as a natural herbal remedy, the potential benefits of P. oceanica for human health are poorly documented. The research group of Prof. Degl'Innocenti of the Department of Biomedical, Experimental and Clinical Sciences "Mario Serio" (University of Florence) was among the first to explore the bioactivities of a hydroalcoholic ex
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21

Nadal, Marina. "Exploring the role of autophagy and cell wall degrading enzymes in the life cycle and pathogenic development of the basidiomycete fungal plant pathogen Ustilago maydis." 2009. http://purl.galileo.usg.edu/uga%5Fetd/nadal%5Fmarina%5F200912%5Fphd.

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22

Chang, Chia-Ting, and 張嘉婷. "Study on the Death Mechanism of Natural Plants on Gastric Cancer and Breast CancerPart IExploration of Mechanism on Flavokawain B-induced Autophagyin Human Gastric Adenocarcinoma;Part IIExploration of Mechanisms on Antrodia salmonea-inducedAutophagy and Apoptosis in Human Triple-negative Breast Cancer(MDA-MB-231) Cells." Thesis, 2017. http://ndltd.ncl.edu.tw/handle/m3526v.

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