Relevant bibliographies by topics / Physicochemical and biological properties

Academic literature on the topic 'Physicochemical and biological properties'

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Published: 30 May 2022
Last updated: 31 May 2022

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Journal articles on the topic "Physicochemical and biological properties"

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Rachkovskaya, L. N., T. V. Popova, A. Yu Letyagin, T. G. Tolstikova, M. A. Korolyov, N. Bogdanchikova, A. N. Pestryakov, A. A. Kotlyarova, V. Burmistrov, and V. I. Konenkov. "Silver containing sorbents: Physicochemical and biological properties." Resource-Efficient Technologies 2, no. 2 (June 2016): 43–49. http://dx.doi.org/10.1016/j.reffit.2016.06.001.

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Parkhomenko, N. I., L. A. Maksymenko, and L. F. Didenko. "Biological and physicochemical properties of cymbidium mosaic virus." Reports of the National Academy of Sciences of Ukraine, no. 10 (October 2020): 71–76. http://dx.doi.org/10.15407/dopovidi2020.10.071.

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The isolated cymbidium mosaic virus (CMV) is one of the most wide-spread and dangerous pathogens that infects promising varieties of orchids. It causes characteristic symptoms on orchid plants, which are manifested in the form of a mosaic. Over time, these areas are necrotized, leading to the stop of flowering the plants and reducing their decorative value. The CyMV is not spread by insects-carriers, but is transmitted by the mechanical inoculation with juice. Electron microscopy revealed flexible filamentous viral particles with a length of about 500 nm. The purified viral preparation is sedimented with a single peak with a sedimentation coefficient of 142S. The floating density of the virus in the preformed CsCl gradient corresponded to 1.3 g/cm3. The electrophoretic analysis of proteins in polyacrylamide gel under denatured conditions showed the presence of two polypeptides with molecular weights of 27 and 31 kDa. RNA CyMV has a molecular weight of 2 · 106 Da. In the translation system of rabbit reticulocytes in vitro, a protein with a molecular weight of about 27 kDa is synthesized. The obtained data allow us to refer CyMV to the group of potexviruses.
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Yoo, Sang-Ho, Kyung Hee Lee, Ji-Soo Lee, Jaeho Cha, Cheon Seok Park, and Hyeon Gyu Lee. "Physicochemical Properties and Biological Activities of DEAE-DerivatizedSphingomonasGellan." Journal of Agricultural and Food Chemistry 53, no. 16 (August 2005): 6235–39. http://dx.doi.org/10.1021/jf050018z.

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Iwahara, Junji, Alexandre Esadze, and Levani Zandarashvili. "Physicochemical Properties of Ion Pairs of Biological Macromolecules." Biomolecules 5, no. 4 (September 30, 2015): 2435–63. http://dx.doi.org/10.3390/biom5042435.

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Imbach, Jean-Louis, Bernard Rayner, and François Morvan. "Sugar-Modified Oligonucleotides: Synthesis, Physicochemical and Biological Properties." Nucleosides, Nucleotides and Nucleic Acids 8, no. 5 (1989): 627–48. http://dx.doi.org/10.1080/07328318908054204.

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Rahmati, Maryam, Eduardo A. Silva, Janne E. Reseland, Catherine A. Heyward, and Håvard J. Haugen. "Biological responses to physicochemical properties of biomaterial surface." Chemical Society Reviews 49, no. 15 (2020): 5178–224. http://dx.doi.org/10.1039/d0cs00103a.

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Oyesomi, Opeyemi O., Ayobami O. Oyedele, Idris A. Oyemitan, Oluwole I. Adeyem, and Anthony A. Elujoba. "Aloe schweinfurthii gel: composition physicochemical and biological properties." International Journal of Complementary & Alternative Medicine 14, no. 1 (February 16, 2021): 26–33. http://dx.doi.org/10.15406/ijcam.2021.14.00529.

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Koloskova, Olesya O., Uliana A. Budanova, Inga C. Shchelik, Igor P. Shilovskii, Musa R. Khaitov, and Yurii L. Sebyakin. "Examination the Properties of Lipopeptide Liposomes Modified by Glycoconjugates." Nano Hybrids and Composites 13 (January 2017): 82–88. http://dx.doi.org/10.4028/www.scientific.net/nhc.13.82.

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Development of transport systems possessing definite physicochemical and biological properties aimed at the targeted delivery of biologically active compounds remains nowadays among urgent problems of the medicine. In this work we made physical chemical and biological tests liposomal drug delivery systems modified with glycolipids for target properties.
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Aguirre-Ramírez, M., H. Silva-Jiménez, I. M. Banat, and M. A. Díaz De Rienzo. "Surfactants: physicochemical interactions with biological macromolecules." Biotechnology Letters 43, no. 3 (February 3, 2021): 523–35. http://dx.doi.org/10.1007/s10529-020-03054-1.

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AbstractMacromolecules are essential cellular components in biological systems responsible for performing a large number of functions that are necessary for growth and perseverance of living organisms. Proteins, lipids and carbohydrates are three major classes of biological macromolecules. To predict the structure, function, and behaviour of any cluster of macromolecules, it is necessary to understand the interaction between them and other components through basic principles of chemistry and physics. An important number of macromolecules are present in mixtures with surfactants, where a combination of hydrophobic and electrostatic interactions is responsible for the specific properties of any solution. It has been demonstrated that surfactants can help the formation of helices in some proteins thereby promoting protein structure formation. On the other hand, there is extensive research towards the use of surfactants to solubilize drugs and pharmaceuticals; therefore, it is evident that the interaction between surfactants with macromolecules is important for many applications which includes environmental processes and the pharmaceutical industry. In this review, we describe the properties of different types of surfactants that are relevant for their physicochemical interactions with biological macromolecules, from macromolecules–surfactant complexes to hydrophobic and electrostatic interactions.
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Gooden, David, Harinath Chakrapani, and Eric Toone. "C-Nitroso Compounds: Synthesis, Physicochemical Properties and Biological Activities." Current Topics in Medicinal Chemistry 5, no. 7 (July 1, 2005): 687–705. http://dx.doi.org/10.2174/1568026054679353.

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Dissertations / Theses on the topic "Physicochemical and biological properties"

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Knaggs, Roger D. "Physicochemical properties of opiates : analytical and biological relevance." Thesis, University of Nottingham, 1997. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.363687.

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Ochoa, Rodríguez Victor Manuel. "Physicochemical and biological properties of Biodentine associated with radiopacifiers /." Araraquara, 2018. http://hdl.handle.net/11449/153853.

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Orientador: Gisele Faria
Resumo: BiodentineTM (BD) apresenta bioatividade, biocompatibilidade e propriedades físico-químicas adequadas; no entanto, não possui radiopacidade adequada. Os objetivos foram avaliar (1) a radiopacidade de BD e BD associado com 15% de tungstato de cálcio (BDCaWO4) ou óxido de zircônio (BDZrO2), empregando sistemas de radiografia convencional e digital; e (2) as propriedades físico-químicas de tempo de presa, pH e solubilidade, e as propriedades biológicas de citocompatibilidade e potencial para induzir mineralização desses cimentos. Para a avaliação da radiopacidade, cada corpo de prova foi radiografado ao lado de uma escada de alumínio usando filme oclusal, placa de fósforo ou sensores digitais. As radiografias convencionais foram digitalizadas por câmera fotográfica ou scanner. Os valores médios de cinza dos materiais foram expressos em milímetros de alumínio (mm Al). A solubilidade foi avaliada após 7 dias de imersão dos espécimes em água destilada e expressa em percentagem de perda de massa. O tempo de presa foi avaliado empregando a agulha de Gillmore (105 ± 0,5 g) e o pH foi mensurado com um medidor de pH. A citocompatibilidade e a bioatividade celular foram avaliadas em células de linhagem osteoblástica (Saos-2) utilizando os ensaios de metiltetrazólio (MTT), vermelho neutro (NR), atividade de fosfatase alcalina (ALP) e coloração de vermelho de alizarina. Os dados foram avaliados utilizando ANOVA de um fator e pós-teste Tukey ou ANOVA de dois fatores e pós-teste de Bonferron... (Resumo completo, clicar acesso eletrônico abaixo)
Abstract: BiodentineTM (BD) presents bioactivity, biocompatibility and suitable physicochemical properties; however, it does not have adequate radiopacity. The objectives were to evaluate (1) the radiopacity of BD and BD associated with 15% calcium tungstate (BDCaWO4) or zirconium oxide (BDZrO2), employing conventional and digital radiography systems; and (2) the physicochemical properties of setting time, pH and solubility, and biological properties of cytocompatibility and potential to induce mineralization of these cements. For radiopacity evaluation, each cement specimen was radiographed alongside an aluminum step-wedge using occlusal film, photostimulable phosphor plates or digital sensors. The conventional radiographies were digitized by digital photographic camera or scanner. Mean grey values of materials were expressed in millimeters of aluminum (mm Al). Solubility was evaluated after 7 days of specimens’ immersion in distilled water and expressed as percentage of mass loss. Setting time was evaluated employing a Gillmore needle (105 ± 0.5 g) and pH was evaluated with pH meter. The cytocompatibility and cell bioactivity were evaluated in osteoblasts-like cells (Saos-2) using methyl-thiazol-tetrazolium (MTT), neutral red (NR), alkaline phosphatase (ALP) activity and alizarin red staining assays. The data were evaluated using one-way ANOVA and Tukey post-test or two-way ANOVA and Bonferroni post-test (α=0.05). BD radiopacity was below 3 mm Al and BDZrO2 and BDCaWO4 was above 3 mm... (Complete abstract click electronic access below)
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Kavatzikidou, Paraskevi. "Ceramics and metals processed by selective laser melting (SLM) : biological and physicochemical properties." Thesis, University of Liverpool, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.479033.

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Queiroz, Marcela Borsatto. "Physicochemical and biological properties of tricalcium silicate-based reparative materials with alternative radiopacifiers and Biosilicate /." Araraquara, 2018. http://hdl.handle.net/11449/153908.

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Orientador: Mário Tanomaru Filho
Abstract: Tricalcium silicate cements associated with radiopacifiers are used as repair materials. Publication 1: Evaluation of tricalcium silicate-based cements (TCS) associated with zirconium oxide (ZrO2), calcium tungstate (CaWO4) or niobium oxide (Nb2O5) radiopacifiers compared to MTA Repair HP (MTA HP). Publication 2: Evaluation of tricalcium silicate-based cements (TCS) associated with zirconium oxide (ZrO2) radiopacifier with 10% or 20% of Biosilicate (TCS ZrO2 + 10% Biosilicate and TCS ZrO2 + 20% Biosilicate) compared to Biodentine. Setting Time (ST) and radiopacity were evaluated based on ISO 6876/2002 standard. Solubility was evaluated according to the method proposed by Carvalho-Júnior et al. (2007) modified. pH was measured at 3, 12 and 24 hours and 7, 14 and 21 days after immersion in distilled water. Cellular cytotoxicity and bioactivity were evaluated by methyltetrazolium (MTT), neutral red (NR), alkaline phosphatase (ALP), alizarin red (ARS) and real time PCR (qPCR) (Publication 1) assays in different periods of contact with eluates of the materials in Saos-2 cells. Antibacterial activity was evaluated by direct contact on Enterococcus faecalis in the planktonic form. For the physico-chemical and ARS tests, the data were submitted to ANOVA and Tukey tests; for MTT, NR and ALP tests the data were analyzed by the Two-Way ANOVA and Bonferroni tests; the antibacterial activity, were submitted to Kruskall-Wallis and Dunn tests (α = 0.05). Publication 1: TCS + CaWO4 presented... (Complete abstract click electronic access below)
Resumo: Cimentos de silicato tricálcico com radiopacificadores são utilizados como materiais reparadores. Publicação 1: Avaliação de cimento à base de silicato tricálcico (STC) associado aos radiopacificadores óxido de zircônio (ZrO2), tungstato de cálcio (CaWO4) ou óxido de nióbio (Nb2O5) em comparação ao MTA Repair HP (MTA HP). Publicação 2: Avaliação de material à base de silicato tricálcico (STC) e radiopacificador óxido de zircônio (ZrO2) e 10% ou 20% de Biosilicato (STC ZrO2 + 10% de Biosilicato e STC ZrO2 + 20% de Biosilicato) em comparação ao Biodentine. Tempo de presa e a radiopacidade foram avaliados seguindo ISO 6876/2002. A solubilidade foi avaliada de acordo com o método proposto por Carvalho-Júnior et al. (2007) modificado. pH foi avaliado 3, 12 e 24 horas, 7, 14 e 21 dias após imersão em água destilada. A citotoxidade e bioatividade celular foram avaliadas pelos testes metiltetrazólio (MTT), vermelho neutro (VN), atividade de fosfatase alcalina (ALP), ensaio de vermelho de alizarina (ARS) e PCR em tempo real (qPCR) (Publicação1), em diferentes períodos de contato com eluídos dos materiais em células Saos-2. Atividade antimicrobiana dos materiais foi avaliada por meio do teste de contato direto com Enterococcus faecalis na forma planctônica. Para os testes físicoquímicos e ARS, os dados foram submetidos aos testes ANOVA e Tukey; para os ensaios do MTT, VN e ALP e qPCR os dados foram analisados aos testes Two Way ANOVA e Bonferroni; os dados da atividade antimicrobiana f... (Resumo completo, clicar acesso eletrônico abaixo)
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Wilds, Christopher James. "Synthesis, physicochemical and biological properties of oligonucleotides containing 2-fluoro-2-deoxy-℗-D-arabinose." Thesis, McGill University, 1999. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=36730.

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Oligonucleotides containing the modification 2-fluoro-2-deoxy-beta-D-arabinose (2'F-ANA) were synthesized via solid phase synthesis in order to investigate their ability to bind to nucleic acids (DNA and RNA). The ability of this modification to serve as a suitable antisense oligonucleotide construct was also evaluated.
All four nucleobase monomers (thymine, cytosine, adenine and guanine) were prepared for solid phase oligonucleotide synthesis, from which homopolymeric and heteropolymeric base sequences were assembled. These molecules bound with very good affinities to both DNA and RNA targets. Structural studies via NMR experiments demonstrated that in a 2'F-ANA/RNA duplex the 2'F-ANA residues adopt an O4' -endo conformation, similar to what has been proposed for the structure of DNA in a DNA/RNA hybrid.
A 2'F-ANA oligopyrimidylate formed a triple-helical complex with duplex DNA and hybrid DNA(Pu):RNA(Py) with an affinity higher than that of a corresponding DNA strand. Also, a cytosine-rich 2' F-ANA strand was found to form a complex at acidic pH which has properties similar to that of i-motif DNA.
Finally, 2'F-ANA strands when hybridized to RNA were found to activate RNase H, an enzyme that is involved in the mechanism of action of antisense drugs. 2'F-ANA is the first example of an antisense analogue that demonstrates improved binding to RNA relative to DNA and still retains the ability to elicit RNase H activity.
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Hellmuth, Isabell [Verfasser]. "Functionally modified (Deoxy)Ribonucleotides : synthesis and study of physicochemical and biological properties / Isabell Hellmuth." Mainz : Universitätsbibliothek Mainz, 2017. http://d-nb.info/1132364590/34.

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Pinzon-Arango, Paola A. "Investigation of the Biological and Physicochemical Properties of Bacillus anthracis Spores during Germination, Virulence, and Killing." Digital WPI, 2012. https://digitalcommons.wpi.edu/etd-dissertations/21.

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Bacillus anthracis has been classified as one of the most dangerous bioterrorism agents causing high mortality rates in short periods of time. Anthrax spores are extremely resistant to chemical and environmental factors, and have the ability to return into a vegetative (virulent) state during the process of germination. Previous research has suggested that spores can be eradicated with common disinfectants after germination and release of spore coats. During germination, the spore coat is degraded, making the spore susceptible to penetration of chemicals into the spore core. While previous research has focused on a qualitative understanding of germination of spores by obtaining high-resolutions images of spore coats to understand how protein coat layers change during germination, very few studies have evaluated changes in mechanical properties of spores during germination, and how germination affects virulence of macrophages. In this study, we performed a series of in vitro experiments to do an in-depth analysis of germination and virulence of B. anthracis. Atomic force microscopy (AFM) was used to investigate changes in spore surface properties during germination including morphology, roughness, elasticity, and spring constant. AFM results suggested that germination mechanisms depend on germinants used to trigger germination and roughness of Bacillus species increase during germination. In addition, the elasticity and spring cell constant of B. anthracis spores are affected during germination since the elastic moduli and cell spring constant values decreased with time as the spore was germinating, making the cells more susceptible. Spore killing was also tested both in sporulated and vegetative B. anthracis using the antimicrobial peptide chrysophsin-3 and the surfactant dodecylamine (DDA). Both killing agents were capable of eradicating B. anthracis spores, but more killing was observed for spores that were germinating or had become vegetative. The presence of germinant receptors from the Ger operon and its role on germination kinetics of B. anthracis was also investigated. The germination of mutant spores that carried one receptor or lacked all germinant receptors was compared to the germination kinetics of wild-type B. anthracis. Our results suggest that germination of spores is modified by the presence or absence of germinant receptors. Furthermore, the mutant B. anthracis strain lacking all receptors germinated suggesting that other receptor independent pathways may exist in B. anthracis. Finally the ability of B. anthracis to adhere, grow, and invade macrophages was investigated. Invasion of macrophages by B. anthracis was dependent on germinant receptors and the ability of spores to germinate and multiply. Our results suggest that macrophages were not capable of killing infecting spores, and on the contrary, germination of spores inside macrophages caused the lysis of macrophages. An uncontrolled release of cytokines by macrophages was elicited by spores and germinated B. anthracis. Our study helps understand the process of germination of B. anthracis spores at a nanomolecular level. Our investigation may be a valuable tool in the design and development of antisporal compounds.
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Ruiz, Hernando María. "Effect of ultrasound, low-temperature thermal and alkali treatments on physicochemical and biological properties of waste activated sludge." Doctoral thesis, Universitat de Barcelona, 2015. http://hdl.handle.net/10803/301434.

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The development of treatment processes to reduce or reuse sewage sludge is crucial for a proper environmental management. Segregating primary from secondary sludge allows for better reuse of secondary sludge, since digested secondary sludge is better suited for agricultural application, containing about double concentration in nutrients but significantly less contaminants. However, secondary sludge (also called waste activated sludge (WAS)) is difficult to dewater compared with primary sludge due to the existence of colloidal materials and extracellular polymeric substances (EPSs), which strongly retain water. WAS is also more difficult to digest under anaerobic conditions due to the presence of glycan strands in microbial cell walls. The low dewaterability and digestibility of WAS can be improved by applying treatments, which can partially disintegrate the WAS by disrupting flocs and cells and solubilising the EPSs. The treatments studied in this thesis were ultrasound, low-temperature thermal and alkali with NaOH. Specifically, it has been analysed the effect of the aforementioned treatment on WAS rheology, dewatering, hygienisation and anaerobic digestion. Rheology is the study of stress-strain relationships of viscoelastic materials. All the sludges analysed (untreated and treated) behaved as non-Newtonian pseudoplastic fluids, which indicates that the viscosity decreases with the applied shear rate. The sludges were also thixotropic (showing a hysteresis area in the plot of stress versus shear rate), which means that the viscosity is time dependent. The three aforementioned treatments resulted in the reduction of the steady state viscosity and the hysteresis area. Complementarily, a rheological structural model was proposed to examine the variations in the thixotropic behaviour of WAS after the application of the treatments. Sludge dewatering is essential to obtain a product dry enough to allow a reduction in storage volume. The three conditions of the thermal treatment (60, 80 and 90 ºC; 1 h, including the heating time to reach the temperature) and the higher intensities of ultrasound (27,000 kJ/kg TS) and alkali (157 g NaOH/kg TS) treatments improved sludge dewatering by centrifugation. To further evaluate the effect of treatments on the sludge dewatering, the EPSs contained in sludge were extracted and characterised. The EPSs were fractionated to generate two different EPS fractions: loosely bound EPSs (LB-EPSs) and tightly bound EPSs (TB-EPSs), where the latter is the innermost fraction and harder to release. An analysis of the untreated sludge revealed that the proteins, followed by the humic acids and polysaccharides, were the major constituents of the EPSs. Each of these components was primarily observed in the TB-EPS fraction. The treatments, particularly the alkali treatment, thoroughly solubilised the EPS, as indicated by the increase in the TOC, protein, humic acid and polysaccharide contents in the LB-EPS fraction. As a result, the dewaterability of WAS was improved. Hygienisation of the sludge is of uttermost importance if the sludge is intended for agriculture. The level of hygienisation was evaluated using three indicator organisms: Escherichia coli, somatic coliphages (SOMCPH) and spores of sulfite-reducing clostridia (SSRC). The thermal treatment at 80 ºC and the alkali treatment at 157 g NaOH kg TS allowed the hygienisation of the sludge, thus satisfying normal levels accepted by the EPA and the 3rd official draft from the EU. Conversely, the conditions tested for the ultrasound treatment barely reduced the levels of microbial indicators. Mesophilic anaerobic digestion is a widely used method to stabilise the sludge. The alkali pre-treatment (157 g NaOH/kg TS) exhibited the greatest methane production increase (34%) followed by the ultrasonication (27,000 kJ/kg TS; 13%), whereas the thermal pre-treatment (80 ºC, 15 min) presented a methane potential similar to the untreated sludge. However, the use of NaOH as a pre-treatment is rather limited because of the rising sodium concentration in the digester.
El desarrollo de procesos para la reducción o reutilización de los lodos resulta determinante para una apropiada gestión medioambiental. Tratando por separado el lodo activado del primario (y no la mezcla como suele hacerse) se favorece el uso del lodo activado en agricultura tras su digestión, ya que el lodo activado contiene el doble de nutrientes y menor carga contaminante que el primario. No obstante, el lodo activado (también denominado lodo secundario o biológico) es más difícil de deshidratar que el primario, ya que presenta una estructura interna organizada de flóculos unidos por las sustancias poliméricas extracelulares (EPSs, por sus siglas en inglés), las cuales atrapan el agua. En este contexto, la reología, que es la ciencia que estudia las relaciones entre la fuerza y la deformación de los materiales, es una herramienta muy útil para la caracterización de la viscosidad o estructura interna de los lodos. El lodo activado es también más difícil de digerir anaeróbicamente debido a las cadenas de glicanos presentes en las paredes celulares de las bacterias. En resumen, para poder deshidratar y digerir un lodo activado será necesario acondicionarlo previamente mediante tratamientos, con el fin de solubilizar las EPSs y aumentar su biodegradabilidad. Si además el lodo quiere destinarse a agricultura deberá estar higienizado. En esta tesis se ha estudiado el efecto de tres tratamientos (ultrasonido, térmico a baja temperatura y alcalino con NaOH) sobre la reología, deshidratación, higienización y digestión anaerobia de lodos activados. Los tres tratamientos redujeron considerablemente la viscosidad del lodo debido a la solubilización de la las EPSs. Así mismo, la solubilización de la EPSs facilitó la expulsión del agua confinada dentro de los flóculos del lodo, mejorando la deshidratación mediante centrifugación. El tratamiento alcalino con dosis de NaOH elevadas fue el que más EPSs solubilizó, de manera que fue el que permitió extraer más agua y el que más aumentó la producción de metano, además de higienizar el lodo. No obstante, este tratamiento tiene el inconveniente de incrementar la concentración de sodio en el digestor, lo cual podría llegar a inhibir el proceso de digestión. Los ultrasonidos redujeron notablemente la viscosidad, además de mejorar la deshidratación y la digestión del lodo. Sin embargo, este tratamiento no fue capaz de higienizar el lodo. El tratamiento térmico a baja temperatura aumentó muy ligeramente la producción de metano (posiblemente debido al corto tiempo de exposición) y permitió deshidratar e higienizar el lodo.
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ElGharib, Mustafa [Verfasser], and Wolfgang [Akademischer Betreuer] Parak. "Enhancing the Physicochemical and Biological Properties of Anisotropic Nanoparticles by Rational Surface Engineering / Mustafa ElGharib ; Betreuer: Wolfgang Parak." Hamburg : Staats- und Universitätsbibliothek Hamburg, 2020. http://d-nb.info/1216629463/34.

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Cable, Colin. "An examination of the effect of surface modifications on the physicochemical and biological properties of non-ionic surfactant vesicles." Thesis, University of Strathclyde, 1990. http://oleg.lib.strath.ac.uk:80/R/?func=dbin-jump-full&object_id=21216.

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The physicochemical properties of non-ionic surfactant vesicles (NSV's), formed from the non-ionic surfactants I. II and IV (monoalkyl and dialkyl polyglyceryl ethers), were examined. The effects of incorporating polyoxyethylene cholesteryl ethers and charged molecules into the vesicular bilayer on these properties were examined and their potential as drug delivery vehicles for doxorubicin (DOX) investigated. The size and aqueous entrapment volume of vesicles were related to the preparation method, although charged molecules or increasing the hydrophilicity did affect both parameters. The vesicular surface charge, due to adsorbed hydroxyl ions or incorporated charged molecules, was reduced as the polyoxyethylene chain length of incorporated cholesteryl ethers was increased. The vesicular charge of vesicles containing cholesteryl polyoxyethylene(24)ether (SOL24) was unaffected by the encapsulation of DOX but encapsulation of the drug in positively charged vesicles markedly affected the charge against pH profile. Increasing the vesicular cholesterol content reduced the enthalpy of the phase transition, ultimately abolishing the peak between 33-50mol% cholesterol, while the peak shape was altered by the addition of charged molecules. Vesicular aggregation was induced by NaCl, although incorporation of charged molecules or SOL24 to the vesicular bilayer prevented this flocculation. DOX release from drug loaded vesicles was markedly reduced by the inclusion of cholesterol or stearylamine (SA) in the bilayer, while the incorporation of SOL24 produced a slight reduction. Empty vesicles containing SOL24 and SA molecules interacted with DOX molecules; SOL24 produced an immediate and reversible interaction and SA produced a delayed but apparently irreversible interaction. Administration of DOX loaded, SOL24 containing vesicles to mice reduced the peak cardiac concentration and produced a higher terminal plasma concentration compared with free drug. The co-administration of free drug with empty vesicles increased drug concentrations in the heart and kidney. The intravenous injection of DOX loaded. SA containing vesicles into mice bearing a subcutaneously implanted ROS tumour gave inconclusive results due to analytical problems, although the injection of empty vesicles with free drug behaved similarly to free drug alone. Drug loaded vesicles were much less effective at retarding tumour growth than either of the free drug containing samples despite fluorescence photomicrographs showing the majority of the vesicles residing within the tumour vasculature.
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Books on the topic "Physicochemical and biological properties"

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Zhang, Suojiang. Ionic liquids: Physicochemical properties. Amsterdam, The Netherlands: Elsevier, 2009.

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Mills, K. C. Physicochemical properties of BOS slags. Luxembourg: Commission of the European Communities, 1986.

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Kinoshita, K. Carbon: Electrochemical and physicochemical properties. New York: Wiley, 1988.

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Zhang, Suojiang, Qing Zhou, Xingmei Lu, Yuting Song, and Xinxin Wang, eds. Physicochemical Properties of Ionic Liquid Mixtures. Dordrecht: Springer Netherlands, 2016. http://dx.doi.org/10.1007/978-94-017-7573-1.

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Pharmaceutical preformulation: The physicochemical properties of drug substances. Chichester: E. Horwood, 1988.

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Wells, James I. Pharmaceutical preformulation: The physicochemical properties of drug substances. New York: Ellis Horwood, 1988.

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Viswanath, Dabir S., Tushar K. Ghosh, and Veera M. Boddu. Emerging Energetic Materials: Synthesis, Physicochemical, and Detonation Properties. Dordrecht: Springer Netherlands, 2018. http://dx.doi.org/10.1007/978-94-024-1201-7.

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Axel, Drefahl, ed. Handbook for estimating physicochemical properties of organic compounds. New York: Wiley, 1999.

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Seidl, Peter H., and Karl H. Schleifer, eds. Biological Properties of Peptidoglycan. Berlin, Boston: De Gruyter, 1986. http://dx.doi.org/10.1515/9783110874297.

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Water-soluble poly-N-vinylamides: Synthesis and physicochemical properties. Chichester: Wiley, 1998.

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Book chapters on the topic "Physicochemical and biological properties"

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Chow, Laurence C., and Milenko Markovic. "Physicochemical Properties of Fluorapatite." In Calcium Phosphates in Biological and Industrial Systems, 67–83. Boston, MA: Springer US, 1998. http://dx.doi.org/10.1007/978-1-4615-5517-9_4.

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Leermakers, Frans A. M., and J. Mieke Kleijn. "Molecular Modelling of Biological Membranes: Structure and Permeation Properties." In Physicochemical Kinetics and Transport at Biointerfaces, 15–111. Chichester, UK: John Wiley & Sons, Ltd, 2004. http://dx.doi.org/10.1002/0470094044.ch2.

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Alekseeva, Olga V., Nadezhda A. Bagrovskaya, and Andrew V. Noskov. "Physicochemical Properties and Biological Activity of Polymethylmethacrylate/Fullerene Composites." In Advances in Nanostructured Composites, 128–39. Boca Raton, FL : CRC Press, Taylor & Francis Group, [2018] | Series: Advances in nanostructured composites ; volume 2 | “A science publishers book.»: CRC Press, 2019. http://dx.doi.org/10.1201/9780429021718-7.

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de Freitas, Caroline, Cárol Cabral Terrone, Carolina Froes Forsan, Adriane M. F. Milagres, and Michel Brienzo. "Oligosaccharides from Lignocellulosic Biomass and Their Biological and Physicochemical Properties." In Clean Energy Production Technologies, 275–309. Singapore: Springer Singapore, 2022. http://dx.doi.org/10.1007/978-981-16-3682-0_9.

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Quadros, Mural, Munira Momin, and Gunjan Verma. "Implications of Synthesis Methodology on Physicochemical and Biological Properties of Hydroxyapatite." In Handbook on Synthesis Strategies for Advanced Materials, 617–58. Singapore: Springer Singapore, 2022. http://dx.doi.org/10.1007/978-981-16-1803-1_15.

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El-Kirat-Chatel, Sofiane, and Audrey Beaussart. "Atomic Force Microscopy Tools to Characterize the Physicochemical and Mechanical Properties of Pathogens." In Nanotechnology to Aid Chemical and Biological Defense, 1–15. Dordrecht: Springer Netherlands, 2015. http://dx.doi.org/10.1007/978-94-017-7218-1_1.

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Langer, A. M., and R. P. Nolan. "Physicochemical Properties of Minerals Relevant to Biological Activities: State of the Art." In In Vitro Effects of Mineral Dusts, 9–24. Berlin, Heidelberg: Springer Berlin Heidelberg, 1985. http://dx.doi.org/10.1007/978-3-642-70630-1_2.

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Fong, Wye-Khay, Thomas L. Moore, Sandor Balog, Dimitri Vanhecke, Laura Rodriguez-Lorenzo, Barbara Rothen-Rutishauser, Marco Lattuada, and Alke Petri-Fink. "Nanoparticle Behaviour in Complex Media: Methods for Characterizing Physicochemical Properties, Evaluating Protein Corona Formation, and Implications for Biological Studies." In Biological Responses to Nanoscale Particles, 101–50. Cham: Springer International Publishing, 2019. http://dx.doi.org/10.1007/978-3-030-12461-8_5.

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Greipel, Joachim, Claus Urbanke, and Günter Maass. "The single-stranded DNA binding protein of Escherichia coli: physicochemical properties and biological functions." In Protein-Nucleic Acid Interaction, 61–86. London: Macmillan Education UK, 1989. http://dx.doi.org/10.1007/978-1-349-09871-2_4.

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Lindblom, Göran, and Leif Rilfors. "Structures Formed by Membrane Lipids — Physicochemical Properties and Possible Biological Relevance for Membrane Function." In Dynamics and Biogenesis of Membranes, 43–64. Berlin, Heidelberg: Springer Berlin Heidelberg, 1990. http://dx.doi.org/10.1007/978-3-642-74194-4_4.

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Conference papers on the topic "Physicochemical and biological properties"

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"Melanin from the lichen Lobaria pulmonaria: physicochemical properties and biological activity." In Plant Genetics, Genomics, Bioinformatics, and Biotechnology. Novosibirsk ICG SB RAS 2021, 2021. http://dx.doi.org/10.18699/plantgen2021-166.

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Lu, Yumeng, Yanlin Sun, and Qingrong Huang. "Effects of Intact Soil Bacterial Community on Plant Growth and Soil Physicochemical Properties." In BIBE2021: The Fifth International Conference on Biological Information and Biomedical Engineering. New York, NY, USA: ACM, 2021. http://dx.doi.org/10.1145/3469678.3469711.

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Carroll, Hyrum, Mark Clement, Quinn Snell, and David McClellan. "ChemAlign: Biologically Relevant Multiple Sequence Alignment Using Physicochemical Properties." In 2009 IEEE International Conference on Bioinformatics and Biomedicine (BIBM). IEEE, 2009. http://dx.doi.org/10.1109/bibm.2009.75.

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"Investigation of Physicochemical, Nutritional, Textural, and Sensory Properties of Iranian Yazdi Cupcake Enriched with Spirulina (Arthrospira platensis)." In International Conference on Latest Trends in Food, Biological & Ecological Sciences. International Academy of Arts, Science & Technology, 2015. http://dx.doi.org/10.17758/iaast.a1015033.

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Ranjous, Yasmin, Géza Regdon, and Tamás Sovány. "The prominence of titanate nanotubes’ functionalization on their physicochemical properties and biological applications as drug delivery system." In II. Symposium of Young Researchers on Pharmaceutical Technology,Biotechnology and Regulatory Science. Szeged: Institute of Pharmaceutical Technology and Regulatory Affairs, University of Szeged, Faculty of Pharmacy, 2020. http://dx.doi.org/10.14232/syrptbrs.2020.op18.

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Rasulev, Bakhtiyor. "APPLICATION OF COMBINED DATA-DRIVEN COMPUTATIONAL CHEMISTRY AND CHEMINFORMATICS APPROACHES TO PREDICT PROPERTIES OF MATERIALS." In 1st INTERNATIONAL Conference on Chemo and BioInformatics. Institute for Information Technologies, University of Kragujevac,, 2021. http://dx.doi.org/10.46793/iccbi21.002r.

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For the last two decades, breakthrough research has been going on in all aspects of materials science at accelerated pace. New materials of unprecedented functionality and performance are being developed and characterized. Moreover, the new materials with improved functionality are in high demand in the marketplace and this need increases in an exponential way for the new materials of desired functionality and performance. Here we show the application of combined computational and cheminformatics methods in various materials properties prediction, including organometallic materials, polymeric materials and nanomaterials. Since most of the materials are complex entities from a chemical point of view, the investigation of them requires an interdisciplinary approach, involving multiple aspects ranging from physics and chemistry to biology and informatics. In this report we show how the combination of computational chemistry, available experimental data, machine learning and cheminformatics approaches can help in materials research and properties assessment, such as physico-chemical properties, toxicity, and biological activity. We discuss here a few case studies where data-driven models developed to reveal the relationships between the physicochemical properties, biological activity and structural characteristics, by application quantum chemical, protein-ligand docking, cheminformatics approaches and developed nanodescriptors.
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Oliveira, Victor, Fernando Castro, Jose Carlos Teixeira, Jorge Araujo, Andre Ribeiro, Joana Carvalho, and Maria Cândida Vilarinho. "Physicochemical Characterization of the Rejected Waste From the Mechanical and Biological Treatment of Municipal Solid Waste." In ASME 2021 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2021. http://dx.doi.org/10.1115/imece2021-73595.

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Abstract Mechanical and Biological Treatment units (MBT), are a key element in the management of municipal solid waste as they are the preferred route for minimization of the amount of waste delivered to landfills. However, taking into account the waste received by the MBT’s, it is observed that a significant part is sent to controlled landfills without any kind of valorization. Within this framework, a characterization of the rejected waste produced in one of these facilities was carried out in order to assess their potential for energy recovery. The rejected waste is composed by different fractions, namely paper, textiles, plastic films, hard plastics, glass, metal, organic matter and undifferentiated waste. In the present work the rejected waste from a MTB unit is sorted into different classes and each one is fully characterized and assessed as an energy source. For the physicochemical characterization of different residues the following tests were performed: weight loss at 105 °C, elemental analysis, the determination of the heating value, thermogravimetric analysis and FTIR spectroscopy. Considering the potential for energetic recovery of the different fractions, only paper, textiles, hard plastics and plastic films were characterized because of the high moisture content of organic material. According to the results, there is a great variability of the physical-chemical properties within the various samples, both in composition and moisture. Most notably the polymer based residues (hard plastics and plastic films) show a heating value that compares favorably with both traditional biomasses and fossil fuels. Therefore, providing their acceptance in terms of toxicity, they can provide a valuable source of energy and contribute to the reduction of waste delivered to landfills.
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P’yanova, L. G., N. V. Kornienko, and A. V. Lavrenov. "Synthesis and study of the physicochemical properties of a carbon sorbent modified by biologically active substances." In INTERNATIONAL CONFERENCE ON PHYSICS AND CHEMISTRY OF COMBUSTION AND PROCESSES IN EXTREME ENVIRONMENTS (COMPHYSCHEM’20-21) and VI INTERNATIONAL SUMMER SCHOOL “MODERN QUANTUM CHEMISTRY METHODS IN APPLICATIONS”. AIP Publishing, 2020. http://dx.doi.org/10.1063/5.0033021.

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Aniket and Ahmed R. El-Ghannam. "Zeta Potential of Silica Calcium Phosphate Nanocomposite: Effect of Material Composition and Medium pH." In ASME 2008 Summer Bioengineering Conference. American Society of Mechanical Engineers, 2008. http://dx.doi.org/10.1115/sbc2008-192883.

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Biodegradable ceramics have lately found exciting applications in orthopedic and maxillofacial surgeries as agents for bone repair, drug delivery vehicles and filling materials. A novel bioactive resorbable ceramic that demonstrated a superior mechanical properties, bioactivity and resorbability compared to traditional calcium phosphate ceramics or bioactive glass is bioactive silica-calcium phosphate nanocomposite (SCPC) [1, 2]. Previous studies have demonstrated that the enhanced bioactivity of SCPC is attributed to its nano structure as well as other physicochemical properties of the material [2]. Surface charge is one of the most important factors that control tissue and cell response to the implant material. Additionally, surface charge enhances the adsorption of biological molecules onto the material surface. The objective of the present work is to investigate the effect of SCPC composition and medium pH on the zeta potential and conductance of the material.
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Timerbulatova, G. A. "METHODOLOGICAL FOUNDATIONS FOR SUBSTANTIATING SAFE LEVELS OF EXPOSURE TO ARTIFICIAL NANOMATERIALS (FOR EXAMPLE, CARBON NANOTUBES)." In The 16th «OCCUPATION and HEALTH» Russian National Congress with International Participation (OHRNC-2021). FSBSI “IRIOH”, 2021. http://dx.doi.org/10.31089/978-5-6042929-2-1-2021-1-506-509.

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Abstract: The unique physicochemical properties of carbon nanotubes allow them to be used in many fields. The global nanomaterials market is growing every year. An important step in introducing products to the domestic and world markets is to determine the safe exposure levels of CNTs. Establishing a corporate standard can serve as a preliminary stage before the approval of a state hygiene standard. Justification of the corporate standard is carried out in in vitro and in vivo experiments. The planning of experiments should be carried out taking into account the target organ under the influence of CNT - the respiratory system. The recommended dose / concentration range for experiments should include doses / concentrations derived from calculated and literature data. A necessary step is to obtain homogeneous dispersions in which CNTs become bioavailable for biological systems. During in vitro and in vivo experiments, the exposure level is determined at which no harmful effect is observed and / or the lowest level of exposure at which there is a harmful effect on the cell culture / respiratory tract of animals.
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Reports on the topic "Physicochemical and biological properties"

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Stoyanova, Daniela D., and Irina D. Stambolova. Effect of Mechanical Activation of CaTiO3 Powder on Some Physicochemical Properties. "Prof. Marin Drinov" Publishing House of Bulgarian Academy of Sciences, December 2018. http://dx.doi.org/10.7546/crabs.2018.12.05.

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Stricklett, K. L., and J. Baker-Jarvis. Electrical properties of biological materials:. Gaithersburg, MD: National Institute of Standards and Technology, 2000. http://dx.doi.org/10.6028/nist.ir.6564.

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Rosencrance, S. The Chemistry, Crystallization, Physicochemical Properties and Behavior of Sodium Aluminosilicate Solid Phases: Final Report. Office of Scientific and Technical Information (OSTI), March 2003. http://dx.doi.org/10.2172/808873.

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Min, Byungrok, Ki Chang Nam, Cheorun Jo, and Dong U. Ahn. Irradiation of Shell Egg on the Physicochemical and Functional Properties of Liquid Egg White. Ames (Iowa): Iowa State University, January 2014. http://dx.doi.org/10.31274/ans_air-180814-1184.

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Singhal, Pooja. Ultra Low Density Shape Memory Polymer Foams With Tunable Physicochemical Properties for Treatment of intracranial Aneurysms. Office of Scientific and Technical Information (OSTI), December 2013. http://dx.doi.org/10.2172/1248313.

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Feng, Xi, Joseph G. Sebranek, and Dong Uk U. Ahn. Addition of Red Wine on the Physicochemical Properties and Sensory Characteristics of Uncured Frankfurter-type Sausage. Ames (Iowa): Iowa State University, January 2018. http://dx.doi.org/10.31274/ans_air-180814-371.

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Haladjova, Emi, Rumena Stancheva, Stergios Pispas, and Stanislav Rangelov. Effect of Concentration on the Physicochemical Properties and Drug Release Profile of Cationic Block Copolymer Aggregates. "Prof. Marin Drinov" Publishing House of Bulgarian Academy of Sciences, December 2021. http://dx.doi.org/10.7546/crabs.2021.12.04.

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Quail, Peter H. Phytochrome from Green Plants: Properties and biological Function. Office of Scientific and Technical Information (OSTI), July 2014. http://dx.doi.org/10.2172/1145411.

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Schnider, Shirley. The biological properties of Pseudomonas aeruginosa bacteriophage 7V. Portland State University Library, January 2000. http://dx.doi.org/10.15760/etd.771.

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Perry, Scott S., and Nicholas Spencer. Fundamental Investigations of the Tribological Properties of Biological Interfaces. Fort Belvoir, VA: Defense Technical Information Center, October 2005. http://dx.doi.org/10.21236/ada438326.

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