Academic literature on the topic 'Physical functioning /SF-36'
Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles
Consult the lists of relevant articles, books, theses, conference reports, and other scholarly sources on the topic 'Physical functioning /SF-36.'
Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.
You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.
Journal articles on the topic "Physical functioning /SF-36"
1
van den Hoek, Joëlle, Leo D. Roorda, Hendriek C. Boshuizen, Gerard J. Tijhuis, Geertrudis A. van den Bos, and Joost Dekker. "Physical and Mental Functioning in Patients with Established Rheumatoid Arthritis over an 11-year Followup Period: The Role of Specific Comorbidities." Journal of Rheumatology 43, no. 2 (January 15, 2016): 307–14. http://dx.doi.org/10.3899/jrheum.150536.
Full textAbstract:
Objective.To investigate the longterm association of a wide range of comorbidities with physical and mental functioning in patients with rheumatoid arthritis (RA).Methods.Longitudinal data over a period of 11 years were collected from 882 patients with RA. Somatic comorbidity and comorbid depression were measured at baseline, with a questionnaire including 20 chronic diseases and with the Center for Epidemiologic Depression Scale, respectively. Physical functioning was measured at 5 timepoints with a disease-specific measure [Health Assessment Questionnaire (HAQ)] and a generic measure [physical scales of the Medical Outcomes Study Short Form-36 (SF-36)]. Mental functioning was measured with the mental scales of the SF-36. To determine the association of baseline-specific comorbidities with functioning over time, we performed longitudinal analyses.Results.At baseline, 72% percent of the patients were women, mean age ± SD was 59.3 ± 14.8 years, median RA disease duration was 5.0 years, and 68% had ≥ 1 comorbid condition. The effect of comorbid conditions was more apparent when physical functioning was measured with SF-36, a disease-generic measure, compared with the HAQ, a disease-specific measure. Circulatory conditions and depression were associated (p < 0.05) with worse physical functioning according to the HAQ. Respiratory conditions, musculoskeletal conditions, cancer, and depression were associated (p < 0.05) with worse physical functioning according to the SF-36. Respiratory conditions and depression were associated with worse mental functioning.Conclusion.Patients with specific comorbid conditions have an increased risk of low functioning in the long term. Targeted attention for these specific comorbid conditions by clinicians is recommended.
2
Saverino, Alessia, Eva Zsirai, Raphael Sonabend, Lorenza Gaggero, Isabella Cevasco, Caterina Pistarini, and Paolo Cremonesi. "Health related quality of life in COVID-19 survivors discharged from acute hospitals: results of a short-form 36-item survey." F1000Research 10 (April 12, 2021): 282. http://dx.doi.org/10.12688/f1000research.50781.1.
Full textAbstract:
Background: Health-related quality of life (HRQL) is important for evaluating the impact of a disease in the longer term across the physical and psychological domains of human functioning. The aim of this study is to evaluate HRQL in COVID-19 survivors in Italy using the short form 36-items questionnaire (SF-36). Methods: This is an observational study involving adults discharged home following a coronavirus disease 2019 (COVID-19)-related hospital admission. Baseline demographic and clinical data including the Cumulative Illness Rating Scale (CIRS) and the Hospital Anxiety and Depression Scale (HADS) were collected. The validated Italian version of SF-36 was administered cross-sectionally. The SF-36 contains eight scales measuring limitations in physical and social functioning, the impact on roles and activities, fatigue, emotional well-being, pain and general health perception. Results: A total of 35 patients, with a mean age of 60 years, completed the SF-36. The results showed difficulties across the physical and psychological domains, particularly affecting the return to previous roles and activities. A higher burden of co-morbidities as well as a more severe muscle weakness was associated to a lower physical functioning. Younger age, rather than older, correlated to a perceived greater limitation in physical functioning and vitality. Conclusions: COVID-19 survivors particularly the ones of working age may need support for resuming their premorbid level of functioning and returning to work.
3
Marn-Vukadinovic, Dusa, and Helena Jamnik. "Validation of the Short Form-36 Health Survey Supported With Isokinetic Strength Testing After Sport Knee Injury." Journal of Sport Rehabilitation 20, no. 3 (August 2011): 261–76. http://dx.doi.org/10.1123/jsr.20.3.261.
Full textAbstract:
Context:Valid patient-based outcome instruments are necessary for comprehensive patient care that focuses on all aspects of health, from impairments to participation restrictions.Objective:To validate the Slovenian translation of Medical Outcome Survey (MOS) Short Form Health Survey (SF-36) and to assess relations among various knee measurements, activity tested with Oxford Knee Score (OKS) and health-related quality of life as estimated with SF-36 domains.Design:Descriptive validation study.Setting:Isokinetic laboratory in outpatient rehabilitation unit.Participants:101 subjects after unilateral sport knee injury.Interventions:All subjects completed the SF-36 and OKS, and isokinetic knee-muscle strength output at 60°/s was determined in 78 participants. Within a 3-d period, 43 subjects completed the SF-36 and OKS questionnaires again.Main Outcome Measures:Reliability testing included internal consistency and test–retest reliability. Correlations between SF-36 subscales and OKS were calculated to assess construct validity, and correlation between SF-36 subscales and muscle strength was calculated to assess concurrent validity.Results:Chronbach α was above .78 for all SF-36 subscales. ICCs ranged from .80 to .93. The correlation between OKS and the physical-functioning subscale, showing convergent construct validity, was higher (r = .83, P < .01) than between OKS and mental health (r = .50, P < .01), showing divergent construct validity. Knee-extensor weakness negatively correlated with physical-functioning (r = −.59, P < .01) and social-functioning (r = −.43, P < .01) subscales.Conclusions:The Slovenian translation of the SF-36 is a reliable and valuable tool. The relationships between knee-muscle strength and activity and between knee-muscle strength and SF-36 subscales in patients after sport knee injury were established.
4
Taylor-Gjevre, Regina M., Anthony Wassef, Bindu Nair, John A. Gjevre, and Thomas Wilson. "A questionnaire assessment of physical function in hyperlipidemic patients." Clinical & Investigative Medicine 33, no. 4 (August 1, 2010): 261. http://dx.doi.org/10.25011/cim.v33i4.14229.
Full textAbstract:
Background: A spectrum of myopathic manifestations has been recognized as associated with lipid lowering drug therapy (LLT), but their effect on quality of life and physical functioning is uncertain. We conducted a prospective cohort study in which physical functioning was the dependent variable, in patients with and without exposure to LLT. Methods: Consecutive patients attending a risk reduction clinic were invited to participate in a questionnaire study which included demographic data, muscular symptoms, the SF-36 Physical Function Score (PF), and the modified Health Assessment Questionnaire (mHAQ). Laboratory and co-morbidity data was recorded. Results: Of 117 consecutive patients invited to participate, 112 consented. Of these, 81 were receiving statins and/or fibrates as LLT and 31 were participating in a non-pharmacologic therapeutic program (NPT) of diet and exercise therapy. The mean age for the total population was 56.7 years (20-78): the LLT group 58.6 and NPT group 51.9 years. Women comprised 53% of the LLT group and 58% of the NPT. No significant differences in baseline lipid profiles, CK level, BMI, waist measurement, gender, cigarette smoking, alcohol consumption, non-steroidal anti-inflammatory drugs or acetaminophen use, frequency of myalgias, SF-36 PF or mHAQ scores were observed between groups. On comparison of gender groups, we observed that men receiving LLT had significantly better SF- 36 PF (p = 0.037) than men on NPT. There were no differences in SF-36 PF or mHAQ scores between groups for females. Conclusion: We found no adverse effects of LLT on physical functioning or quality of life. Indeed, men treated with LLT had significantly better SF-36 PF scores than men treated non-pharmacologically.
5
Davidson, Megan, Jennifer L. Keating, and Sophie Eyres. "A Low Back-Specific Version of the SF-36 Physical Functioning Scale." Spine 29, no. 5 (March 2004): 586–94. http://dx.doi.org/10.1097/01.brs.0000103346.38557.73.
Full text
6
Grande, Gunn E., Morag C. Farquhar, Stephen I. G. Barclay, and Christopher J. Todd. "Quality of life measures (EORTC QLQ-C30 and SF-36) as predictors of survival in palliative colorectal and lung cancer patients." Palliative and Supportive Care 7, no. 3 (September 2009): 289–97. http://dx.doi.org/10.1017/s1478951509990216.
Full textAbstract:
AbstractObjective:Self-reported health-related quality of life (HRQoL) is an important predictor of survival alongside clinical variables and physicians' prediction. This study assessed whether better prediction is achieved using generic (SF-36) HRQoL measures or cancer-specific (EORTC QLQ-C30) measures that include symptoms.Method:Fifty-four lung and 46 colorectal patients comprised the sample. Ninety-four died before study conclusion. EORTC QLQ-C30 and SF-36 scores and demographic and clinical information were collected at baseline. Follow-up was 5 years. Deaths were flagged by the Office of National Statistics. Cox regression survival analyses were conducted. Surviving cases were censored in the analysis.Results:Univariate analyses showed that survival was significantly associated with better EORTC QLQ-C30 physical functioning, role functioning, and global health and less dyspnea and appetite loss. For the SF-36, survival was significantly associated with better emotional role functioning, general health, energy/vitality, and social functioning. The SF-36 summary score for mental health was significantly related to better survival, whereas the SF-36 summary score for physical health was not. In the multivariate analysis, only the SF-36 mental health summary score remained an independent, significant predictor, mainly due to considerable intercorrelations between HRQoL scales. However, models combining the SF-36 mental health summary score with diagnosis explained a similar amount of variance (12%–13%) as models combining diagnosis with single scale SF-36 Energy/Vitality or EORTC QLQ-C30 Appetite Loss.Significance of results:HRQoL contributes significantly to prediction of survival. Generic measures are at least as useful as disease-specific measures including symptoms. Intercorrelations between HRQoL variables and between HRQoL and clinical variables makes it difficult to identify prime predictors. We need to identify variables that are as independent of each other as possible to maximize predictive power and produce more consistent results.
7
Kitajima, Izuru, Kazureru Doi, Yasunori Hattori, Semih Takka, and Emmanuel Estrella. "EVALUATION OF QUALITY OF LIFE IN BRACHIAL PLEXUS INJURY PATIENTS AFTER RECONSTRUCTIVE SURGERY." Hand Surgery 11, no. 03 (January 2006): 103–7. http://dx.doi.org/10.1142/s0218810406003279.
Full textAbstract:
To evaluate the subjective satisfaction of brachial plexus injury (BPI) patients after surgery based on the medical outcomes study 36-item short form health survey (SF-36) and to correlate their SF-36 scores with upper extremity functions. Four items were assessed statistically for 30 patients: SF-36 scores after BPI surgery were compared with Japanese standard scores; the correlation between SF-36 scores and objective joint functions; difference in SF-36 scores between each type of BPI; and influence of each joint function on the SF-36 scores. The SF-36 subscale: PF — physical functioning, RP — role-physical, BP — bodily pain, and the summary score PCS — physical component summary, were significantly inferior to the Japanese standard scores. SF-36 is more sensitive to shoulder joint function than to elbow and finger joint functions. Little correlation was found between SF-36 scores and objective evaluations of joint functions. Greater effort is needed to improve the quality of life (QOL) of BPI patients. This study showed that SF-36 is not sensitive enough to evaluate regional conditions. A region- or site-specific questionnaire is required to evaluate upper extremity surgery.
8
Kuan, Edward, Frederick Yoo, Jennifer Chyu, Angela Oh, Marvin Bergsneider, and Marilene Wang. "Quality of Life before and after Endoscopic Pituitary Surgery as Measured by the Short-Form-36." Journal of Neurological Surgery Part B: Skull Base 79, no. 03 (November 7, 2017): 314–18. http://dx.doi.org/10.1055/s-0037-1608648.
Full textAbstract:
Objectives/Hypotheses To assess quality of life (QOL) after transnasal, endoscopic pituitary surgery using the 36-item short form (SF-36) instrument. Design Retrospective review was used for this study. Setting The study was conducted in a tertiary academic medical center. Participants Patients who underwent endoscopic, transnasal, transsphenoidal surgery for pituitary adenomas between January 1, 2007 and July 1, 2016 and completed preoperative and postoperative SF-36 surveys. Main Outcome Measures SF-36 survey data as measured by its eight domains (physical functioning, physical role functioning, emotional role functioning, energy/fatigue, emotional well-being, social functioning, pain, and general health). Results There were 18 preoperative, 13 short-term (2 weeks or less after surgery) postoperative, and 14 longer term (>2 weeks after surgery) postoperative surveys. There was no significant difference between preoperative and long-term postoperative SF-36 scores across domains (p > 0.05). In comparing short-term postoperative and preoperative scores, tumor size was positively associated with emotional well-being (p = 0.049) and general health scores (p = 0.031), while visual changes preoperatively were positively associated with general health scores (p = 0.046). Compared with standard U.S. general population summary data, these patients scored lower preoperatively in all domains except for emotional role functioning and pain (p < 0.05). Postoperatively, patients improved to baseline general population data scores with the exception of the physical role functioning domain (p < 0.0001). Conclusion Patients undergoing endoscopic, transnasal, transsphenoidal surgery for pituitary adenomas had lower QOL in six of eight domains preoperatively, but improved to baseline values on the long run after surgery in seven of eight domains. This suggests that minimally invasive pituitary surgery has a restorative role in general QOL as measured by the SF-36.
9
Strohonova, Tatyana, Maria Bondar, and Suren Varzhapetian. "Discriminant analysis for defining quality of life patients with comorbid pathology of osteoarthrosis." Proceedings of the International Conference on Applied Statistics 1, no. 1 (October 1, 2019): 458–62. http://dx.doi.org/10.2478/icas-2019-0039.
Full textAbstract:
Abstract There has been a shift in medicine from relying on clinical biomarkers to including patient-reported outcome measures. From a healthcare perspective, health-related quality of life (HRQOL) measures can be used to enhance patient care and reducing treatment cost for patients. Given the possible importance of Medical Outcome Study in medicine, and the conflicting reports in literature about its use in healthcare, it is important to identify its utility within the medical community. In this study 150 people were recruited prospectively from patients at the Hospital and the emergency сenter №1 in Zaporizhzhya, Ukraine. Four groups were formed. The inclusion criteria to group were different comorbid pathology of osteoarthrosis. We assessed patients HRQOL SF-36 SF-36 changes before and after pharmacotherapy (over 1 year), than it were compared with the control group. The validity of the construct has been analyzed by discriminant analysis. To assess SF-36 ability identifying discriminating functions were developed, determine its prediction value, define which scales of SF-36 are the best predictors for every groups. In addition, canonical analysis demonstrates SF-36 ability to estimate effect of pharmacotherapy. Statistical analysis show that all indices quality of life through SF – 36 scales except of third (physical role functioning, physical functioning, emotional role functioning) have prognostic value (p>0.05) and validity of SF-39 scales for examination of the patients with coexisting disease is statistically significant(p<0.05).
10
Janssens, A. CJW, P. A. van Doorn, J. B. de Boer, N. F. Kalkers, F. GA van der Meché, J. Passchier, and R. Q. Hintzen. "A nxiety and depression influence the relation between disability status and quality of life in multiple sclerosis." Multiple Sclerosis Journal 9, no. 4 (August 2003): 397–403. http://dx.doi.org/10.1191/1352458503ms930oa.
Full textAbstract:
Disability status, depression and anxiety are important determinants of quality of life (Q oL) in patients with multiple sclerosis (MS). We investigated whether anxiety and depression influence the relation between disability status and Q oL in our cohort of recently diagnosed patients. Disability status [Expanded Disability Status Scale (EDSS)], anxiety and depression [Hospital A nxiety and Depression Scale (HADS)], and Q oL (SF-36) were prospectively obtained in 101 MS patients. The relation between EDSS and SF-36 scales was examined using regression analyses, without and with adjustment for anxiety and depression. Interaction effects were investigated by comparing the relation between EDSS and Q oL in patients with high and low anxiety and depression. In the unadjusted analyses, EDSS was significantly related to all SF-36 physical and mental health scales. A fter adjustment for anxiety and depression, EDSS was significantly related only to the SF-36 physical functioning, role-physical functioning and bodily pain scales. The relation between EDSS and these SF-36 scales was consistently higher in patients with more symptoms of anxiety or depression, suggesting that anxiety and depression strengthened the association of EDSS in these SF-36 physical health scales. A fter adjustment for anxiety and depression, EDSS was not significantly related to the SF-36 mental health scales and the general health scale. This finding is compatible with the hypothesis that anxiety and depression are intermediate factors in the association of EDSS with these SF-36 scales. Screening for symptoms of anxiety and depression is recommended in studies that use Q oL as an outcome measure of treatment or intervention efficacy.
Dissertations / Theses on the topic "Physical functioning /SF-36"
1
Alizadeh, khoei Mahtab. "Assessing factors in utilisation of health services and community aged care services by the Iranian elderly living in the Sydney metropolitan area." Thesis, The University of Sydney, 2008. http://hdl.handle.net/2123/3986.
Full textAbstract:
Abstract As one of the most culturally diverse countries in the world, Australia has a high proportion of minority communities. However, its ageing population, particularly within these ethnic minorities, faces a range of barriers or difficulties in gaining access to and using health and aged care services. This study aims to identify the acculturation factors that affect the health status of Iranian-born elderly immigrants to Australia and their utilisation of health and community aged care services. The results of this study will be of value to Iranian elders, their families, and Australian aged health care service providers. The findings could also contribute towards enriched multicultural policy and improved social fairness, access to services, and equity for the aged from different ethnic backgrounds. 302 Iranian migrants aged 65 years who had lived in the Sydney Metropolitan area for at least six months were surveyed via a written questionnaire, face-to-face interviews, and telephone interviews. The results were analysed using SPSS and then compared to the findings from a 1999 survey of NSW elderly. The results indicate that Iranian migrants suffer higher levels of psychological distress and are more limited in their physical functioning than the general population of older Australians. They are in greater need of assistance with activities of daily living, have a lower sense of wellbeing, and are far less likely to utilise aged care services. Iranian migrant who do not speak English at home experience these disadvantages to an even greater extent English language proficiency was the only acculturation factor found to affect whether Iranian elderly utilised health and community aged care services, while ability to engage in activities of daily living (ADL) was the only health variable associated with their utilisation of community supportive aged care services. This variable did not predict the use of community aged care services in the broader sample of NSW respondents. Since limited proficiency in English placed elderly Iranian migrants at greater health risk and impeded their access to necessary assistance, the findings suggest that they would clearly benefit from English classes and from access to health and community care services and information regarding these services in the Farsi language.
2
Alizadeh, khoei Mahtab. "Assessing factors in utilisation of health services and community aged care services by the Iranian elderly living in the Sydney metropolitan area." University of Sydney, 2008. http://hdl.handle.net/2123/3986.
Full textAbstract:
Doctor of philosophy (PhD)Abstract As one of the most culturally diverse countries in the world, Australia has a high proportion of minority communities. However, its ageing population, particularly within these ethnic minorities, faces a range of barriers or difficulties in gaining access to and using health and aged care services. This study aims to identify the acculturation factors that affect the health status of Iranian-born elderly immigrants to Australia and their utilisation of health and community aged care services. The results of this study will be of value to Iranian elders, their families, and Australian aged health care service providers. The findings could also contribute towards enriched multicultural policy and improved social fairness, access to services, and equity for the aged from different ethnic backgrounds. 302 Iranian migrants aged 65 years who had lived in the Sydney Metropolitan area for at least six months were surveyed via a written questionnaire, face-to-face interviews, and telephone interviews. The results were analysed using SPSS and then compared to the findings from a 1999 survey of NSW elderly. The results indicate that Iranian migrants suffer higher levels of psychological distress and are more limited in their physical functioning than the general population of older Australians. They are in greater need of assistance with activities of daily living, have a lower sense of wellbeing, and are far less likely to utilise aged care services. Iranian migrant who do not speak English at home experience these disadvantages to an even greater extent English language proficiency was the only acculturation factor found to affect whether Iranian elderly utilised health and community aged care services, while ability to engage in activities of daily living (ADL) was the only health variable associated with their utilisation of community supportive aged care services. This variable did not predict the use of community aged care services in the broader sample of NSW respondents. Since limited proficiency in English placed elderly Iranian migrants at greater health risk and impeded their access to necessary assistance, the findings suggest that they would clearly benefit from English classes and from access to health and community care services and information regarding these services in the Farsi language.
Book chapters on the topic "Physical functioning /SF-36"
1
Regassa Feyisa, Bikila. "Predictors of Health-Related Quality of Life among Patients with Diabetes Mellitus." In Quality of Life Modifiers Due to Biological, Psychological, and Societal Factors [Working Title]. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.99179.
Full textAbstract:
The health of general population cannot be well characterized from the analyses of mortality and morbidity statistics alone, particularly for patients of chronic diseases including diabetes mellitus. It is equally important to contemplate health in terms of people’s assessment of their sense of well-being and ability to perform social roles. A number of reasons are there to measure the health-related quality of life among patients with diabetes mellitus. For one thing, diabetes patients are highly interested in functional capacity and well-being. On the other hand, patients in the same clinical manifestations might have different responses. Either general or specific instruments could be utilized to measure the health-related quality of life of diabetes patients. Choice of the instrument depends on time of the measurement, validity of the instrument and the interpretability. In Ethiopia, short form 36 (SF-36) instruments were utilized and the highest (63.2 ± 34.4) and the lowest (30.2 ± 22.9) mean score scored in physical functioning and general health domain respectively. The study indicated that age, sex, marital status, educational status, feeling of stigmatized, co-morbidity status, chronic complication and body mass index are some of the predictors of health-related quality of life for patients living with diabetes mellitus.
Conference papers on the topic "Physical functioning /SF-36"
1
Faisal, Eman, Mohammed Al- Hashem, Theodoros Papasavvas, and Karam Turk-Adawi. "Is there an association between Attending Cardiac Rehabilitation Program and Healthrelated Quality of Life among Patients in Qatar?" In Qatar University Annual Research Forum & Exhibition. Qatar University Press, 2020. http://dx.doi.org/10.29117/quarfe.2020.0157.
Full textAbstract:
Introduction: Cardiovascular disease (CVD) is the primary cause of death worldwide. More patients with CVD are living than before due to medical advancements. Therefore, there is an urgent need for secondary prevention strategies. Cardiac rehabilitation (CR) is a secondary prevention model of care for the management of CVD. Aim: This is the first study to explore the association between attending at least the median number of CR sessions and change in HRQOL among patients in Qatar. Methods: This retrospective cohort study included all patients who were enrolled in the CR program in Qatar. Secondary data were extracted from patients’ records before the CR program (pre-CR) and at patient discharge (post-CR). The SF-36 instrument was used to assess HRQOL among patients. Results: The study involved 396 (91.4%) males; the mean age was 52.7±9.8 (SD) years. There was a statistically significant association between attending at least the median number of CR sessions and change in physical functioning scores (95% CI=8.85-29.11/ p-value=0.002), change in social functioning scores (95% CI=0.04-19.38/ p-value=0.04), change in emotional well-being scores (95% CI= 1.92-22.13/ p-value=0.02), and change in general health scores (95% CI=0.38-16.42/ p-value= 0.03), as compared to attending less than the median number of sessions. The models adjusted for age, gender, comorbidities, risk level, depression, and baseline HRQOL scores. Conclusion: CR program improved HRQOL. Therefore, there is a need to promote CR utilization and to implement strategies to keep patients in programs. These findings could motivate policymakers to expand CR program capacity, as the sole program in Qatar.
2
Iakovleva, Maria, Olga Shchelkova, and Ekaterina Usmanova. "QUALITY OF LIFE OF PATIENTS UNDERGOING SURGICAL TREATMENT OF LOWER LIMB CANCER." In International Psychological Applications Conference and Trends. inScience Press, 2021. http://dx.doi.org/10.36315/2021inpact021.
Full textAbstract:
"Patients suffering from oncological diseases are the focus of attention of both physicians and psychologists. Although tumor lesions of bones and soft tissues are a relatively rare condition, its effect on the person’ mind and lifestyle are significant, and its treatment is a challenge, also in terms of patient’s adaptation to the disease and therapy. There are various strategies for treating this pathology; all of them are associated with high-tech medicine focused on maintaining or improving patients’ quality of life (QoL). The aim of the present research is to study the psychological characteristics and QoL of patients undergoing surgical treatment of tumor lesions of bones and soft tissues of lower limbs. Material and methods. 36 patients were examined (mean age 58,22; 19 – men). The SF-36 questionnaire, Ways of Coping Questionnaire (WCQ), and Big Five Personality Test (BFI) were used. Treatment by means of the isolated limb perfusion technique was prescribed to 15 patients (group 1); 21 patients were subjected to lower limb amputation due to their disease (group 2). Results. It was found that patients who underwent amputation are characterized by lower rates on the coping scale ‘accepting responsibility’ than patients from the perfusion group (p < 0.05); at the same time, patients from the second group had higher values on the ‘openness’ scale of the BFI compared to the first group (p < 0.1). The study of the relationship between patients’ QoL parameters, personality and coping showed that in the first group the values on the coping scale ‘seeking social support’ negatively correlate with ‘bodily pain’ (p < 0.01), and ‘escape–avoidance’ negatively correlates with ‘social functioning’ (p < 0.01). In the second group, the following significant correlations between personality traits and QoL were revealed: ‘extraversion’ is positively associated with ‘physical functioning’, ‘role-emotional’ and ‘mental health’ (p < 0.01), ‘agreeableness’ has a negative correlation with ‘bodily pain’ and ‘general health’ (p < 0.01), ‘neuroticism’ is negatively related with ‘bodily pain’ and ‘general health’ (p < 0.01), ‘openness’ is positively associated with ‘bodily pain’ and ‘general health’ (p < 0.01). Conclusion. The data obtained emphasizes the importance of taking into account personality characteristics in the management of patients with cancer, including tumor lesions of the bones and soft tissues, as well as the dynamic nature of QoL and its close interconnection with the stage and strategy of treatment and patients’ personality. Psychological support for patients is required for their successful adaptation to the illness and therapy. Acknowledgement. This research was supported by the Russian Foundation for Basic Research (RFBR) (Grant No 20-013-00573)."