Relevant bibliographies by topics / Pharmaceutical chemistry

Contents

  1. Journal articles
  2. Dissertations / Theses
  3. Books
  4. Book chapters
  5. Conference papers
  6. Reports

Academic literature on the topic 'Pharmaceutical chemistry'

Author: Grafiati
Published: 4 June 2021
Last updated: 29 July 2024

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Journal articles on the topic "Pharmaceutical chemistry"

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Olivero, Roberto. "The pharmaceutical chemist Juan José Olivero, reference of uruguayan science and the pharmaceutical industry." Anales de la Real Academia Nacional de Farmacia 89, no. 89(03) (September 30, 2023): 387–94. http://dx.doi.org/10.53519/analesranf.2023.89.03.10.

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Pharmaceutical chemist (doctor) Juan José Olivero Muñoz (Buenos Aires, 1921-Montevideo, 1993) was one of the outstanding professionals in the uruguayan pharmaceutical teaching and industry. He worked as a technician in the laboratories Athena; EMAR (Eduardo Márques Castro S. A.) and Dispert. A specialist in antibiotics, he also developed different products. He studied chloromycetin, publishing in Annals of the Uruguayan Chemistry anf Pharmacy Association and Chemical Abstracts. He was author of papers on hydrotropization in pharmaceutical technology; chemical titration of diphenhydramine hydrochloride elixir and solvotropization of steroid hormones. He wrote several chapters of the encyclopedia Theoretical and practical Pharmacotechnics, a reference text. He was president of the Uruguayan Chemistry and Pharmacy Association and was a professor and advisor of the Faculty of Chemistry in several subjects, mainly Pharmacotechnics. From 1966 until his death, he was a member of the Royal National Academy of Pharmacy (Spain), an honor to which few chemists had access in our country. After his death, he was recognized as one of the leading figures of the profession in Uruguay.
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Lafont, Olivier. "Pharmaceutical Chemistry." European Journal of Medicinal Chemistry 37, no. 8 (August 2002): 707. http://dx.doi.org/10.1016/s0223-5234(02)01395-8.

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Tauro, Dr Savita J., and Jineetkumar B. Gawad. "Green Chemistry: A Boon to Pharmaceutical Synthesis." International Journal of Scientific Research 2, no. 7 (June 1, 2012): 67–69. http://dx.doi.org/10.15373/22778179/july2013/22.

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Gopiwad, Prachit. "Medicinal chemistry of catechol, a versatile pharmacophore." Current Trends in Pharmacy and Pharmaceutical Chemistry 6, no. 1 (February 15, 2024): 7–11. http://dx.doi.org/10.18231/j.ctppc.2024.003.

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Catechol being a versatile pharmacophore, used in medicine as a molecular group in adjunction with other moieties and functional groups. The versatile pharmacophore has rendered several useful pharmaceuticals so far. The major medicines or the pharmaceutical drugs containing catechol moiety include levodopa, carbidopa, and several others. The FDA approved pharmaceutical preparations have been highlighted and reviewed in this paper.
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Mondal, Dipayan, Pankaj Lal Kalar, Shivam Kori, Shovanlal Gayen, and Kalpataru Das. "Recent Developments on Synthesis of Indole Derivatives Through Green Approaches and Their Pharmaceutical Applications." Current Organic Chemistry 24, no. 22 (December 18, 2020): 2665–93. http://dx.doi.org/10.2174/1385272824999201111203812.

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Indole moiety is often found in different classes of pharmaceutically active molecules having various biological activities including anticancer, anti-viral, anti-psychotic, antihypertensive, anti-migraine, anti-arthritis and analgesic activities. Due to enormous applications of indole derivatives in pharmaceutical chemistry, a number of conventional synthetic methods as well as green methodology have been developed for their synthesis. Green methodology has many advantages including high yields, short reaction time, and inexpensive reagents, highly efficient and environmentally benign over conventional methods. Currently, the researchers in academia as well as in pharmaceutical industries have been developing various methods for the chemical synthesis of indole based compounds via green approaches to overcome the drawbacks of conventional methods. This review reflects the last ten years developments of the various greener methods for the synthesis of indole derivatives by using microwave, ionic liquids, water, ultrasound, nanocatalyst, green catalyst, multicomponent reaction and solvent-free reactions etc. (please see the scheme below). Furthermore, the applications of green chemistry towards developments of indole containing pharmaceuticals and their biological studies have been represented in this review.
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Vose, Colin W., Robin Whelpton, Alison E. Ashcroft, Jeremy R. Everett, J. K. Nicholson, I. D. Wilson, Andrew J. Hutt, E. David Morgan, Huiping Huang, and Ian D. Wilson. "Biomedical and pharmaceutical chemistry." Analytical Proceedings 28, no. 6 (1991): 177. http://dx.doi.org/10.1039/ap9912800177.

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Byrn, S. R., R. R. Pfeiffer, G. Stephenson, D. J. W. Grant, and W. B. Gleason. "Solid-State Pharmaceutical Chemistry." Chemistry of Materials 6, no. 8 (August 1994): 1148–58. http://dx.doi.org/10.1021/cm00044a013.

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Veronese, F. M., and M. Morpurgo. "Bioconjugation in pharmaceutical chemistry." Il Farmaco 54, no. 8 (August 1999): 497–516. http://dx.doi.org/10.1016/s0014-827x(99)00066-x.

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Ahsan, Haseeb, Salman Ul Islam, Muhammad Bilal Ahmed, Young Sup Lee, and Jong Kyung Sonn. "Significance of Green Synthetic Chemistry from a Pharmaceutical Perspective." Current Pharmaceutical Design 26, no. 45 (December 24, 2020): 5767–82. http://dx.doi.org/10.2174/1381612826666200928160851.

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Background: Conventional practices of synthesis, manufacturing, and processing have led to severe adverse consequences for living beings and the environment. Objectives: Although medications cannot be replaced, the methods of synthesizing, manufacturing, and processing them can be changed and/or replaced. This paper explains the significance of green chemistry practices in the pharmaceutical industry. It emphasizes that we must replace conventional drug synthesis, processing, and manufacturing techniques with greener ones that are cost-effective, sustainable, environment-friendly, and profitable. Discussion: This paper comprises five sections. Section 1 is an introduction to green chemistry and its correlation with the pharmaceutical industry. Section 2 discusses the metrics necessary to measure the greenness of a process. Section 3 is about solvents used in the pharmaceutical industry, hazards, safety status, and environmental effects, including the ozone depletion potential. Section 4 explains catalytic amidation reactions because amides are one of the most commonly occurring functional groups with pharmacological activity. Section 5 discusses successful cases of converting conventional synthesis of active pharmaceutical ingredients and/or their intermediates to greener, sustainable alternatives. Conclusion: A balance is necessary between profits, processes, consumers, and the environment to ensure the survival of all stakeholders and decrease the environmental burden of pharmaceuticals. Incentives such as green chemistry awards should be endorsed and encouraged, in addition to making green chemistry part of tertiary education. In addition, changes to rules and regulations for drug approval in the context of green chemistry principles are necessary in order to preserve our planet for future generations.
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Cheaburu-Yilmaz, Catalina Natalia, Sinem Yaprak Karavana, and Onur Yilmaz. "Functionalized Chitosan for Pharmaceutical Applications." Current Organic Synthesis 14, no. 6 (September 28, 2017): 785–97. http://dx.doi.org/10.2174/1570179414666161115150818.

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Background: Chitosan structure versatility toward a change in an external stimulus represents a “must have” for the pharmaceutical applications, especially for the pharmaceutical formulations. Chemical modification can open new ways to obtain materials with tailored properties. Despite the great interest for conventional graft modifications, controlled/living free radical polymerizations (i.e. RAFT, ATRP, etc.) and advanced chemistry techniques (i.e. click chemistry) seem more attractive nowadays and involve facile and fast procedure, high regioselectivity, quantitative yield, mild reaction conditions without generation of by-products. Objective: The present review provides a detailed state of art of the chemical modification of chitosan i.e. tailored side-chain functionalization using RAFT polymerization and click chemistry for specific applications within pharmaceutical formulations taking into account the applicative aspect regarding the need of pharmaceuticals. Conclusion: The review showed the routes of current approaches for side chain modification of chitosan including graft, block copolymers or other structural variations. The esterification of RAFT agents on chitosan by using carbonyl activating reagents enables producing chitosan graft and block copolymers with controlled architectures while the development of protection/ deprotection chemistry of chitosan made possible the regioselective modification of chitosan or other polysaccharides. Although these developments increased the potential of chitosan, still the chemical functionality and architectural diversity of the derivatives are limited. Application of modern techniques e.g. RAFT polymerization, “click” chemistry has opened new “doors” for the science of controlled and chemoselective synthesis of well- tailored derivatives with unique and superior properties.
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Dissertations / Theses on the topic "Pharmaceutical chemistry"

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Raynel, Guillaume. "Application of green chemistry principles to the pharmaceutical industry." Thesis, University of Leeds, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.553778.

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Vallin, Karl S. A. "Regioselective Heck Coupling Reactions : Focus on Green Chemistry." Doctoral thesis, Uppsala University, Department of Medicinal Chemistry, 2003. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-3380.

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Carbon-carbon bond formation reactions are among the most important processes in chemistry, as they represent key steps in the synthesis of more complex molecules from simple precursors. This thesis describes mainly the development of novel regioselective applications of the mild and versatile palladium-catalyzed carbon-carbon coupling method, commonly known as the Heck reaction. In addition, this thesis will focus on environmentally friendly developments of the Heck reaction.

Novel ligand-controlled internal Heck vinylations of vinyl ethers and enamides to form branched electron-rich dienes were performed with high regioselectivity. The vinylation of 2-hydroxyethyl vinyl ether permits a chemoselective transformation of a vinylic triflate or bromide into a blocked α,β-unsaturated methyl ketone. Furthermore, a simple separation of the palladium catalyst was achieved with new fluorous-tagged bidentate ligands in combination with fluorous solid phase extraction. The reaction times could be reduced up to 1000 times with controlled microwave heating in the palladium-catalyzed reactions with, in the majority of cases, retained, high selectivity.

The development of a “green” regioselective arylation and vinylation method relying on an aqueous DMF-potassium carbonate system and excluding the toxic thallium salt has been accomplished. Ionic liquids as the versatile and environmentally friendly class of solvents have been used in rapid phosphine-free terminal Heck arylations with controlled microwave heating. Recycling of the catalytic medium was achieved after a simple product purification.

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Brown, Stacy D., Andy Coop, Paul Trippier, and Eric Walters. "Contemporary Approaches For Teaching Medicinal Chemistry." Digital Commons @ East Tennessee State University, 2017. https://dc.etsu.edu/etsu-works/5251.

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As the profession of pharmacy has transitioned from a chemistry-centered profession to a patient-centered profession, the role of medicinal chemistry in the curriculum has evolved. There is decreased emphasis on memorization of chemical structures, and priority placed on relating these structures to ADME, physical properties, and pharmacodynamics. Simultaneously, the delivery of this content has shifted from traditional lecture format to other styles. Here we discuss some new approaches to teaching medicinal chemistry.
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O'Neill, Catherine A. "Formulation of pharmaceutical gels." Thesis, Queen's University Belfast, 1992. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.317524.

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Mukherjee, Sreya. "Crystal Engineering of Pharmaceutical Cocrystals." Scholar Commons, 2011. http://scholarcommons.usf.edu/etd/3258.

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Pharmaceutical cocrystals use principles of crystal engineering for the design of crystalline forms of drugs and can improve their solubility, bioavailability, stability and other important properties without changing the efficacy of the drug. Herein reported are pharmaceutical cocrystals of two API's, caffeine and Pentoxifylline. Research has indicated that caffeine has the ability to reverse AB; plaque deposition in the brain (believed to be the primary cause of Alzheimer's pathogenesis) and thus revert memory and improve cognitive impairment. But owing to the fast absorption rate and short half life, a controlled release formulation of caffeine would be clinically beneficial. Thus, novel cocrystals of caffeine are presented with varying solubilities with respect to caffeine. The pharmaceutical cocrystals of caffeine used herein include: caffeine.cyanuric acid monohydrate, caffeine.syringic acid tetrahydrate, caffeine.chlorogenic acid and caffeine.catechin hydrate. Three caffeine cocrystals were prepared in our lab previously which include caffeine.ferulic acid, caffeine.ethyl gallate dihydrate and caffeine.caffeic acid. In addition, six caffeine cocrystal forms were reproduced from the literature and included in the solubility study: caffeine.quercetin, caffeine.salicylic acid, caffeine.1-hydroxy-2-napthoic acid, caffeine.gallic acid hemihydrate, caffeine.ellagic acid monohydrate and caffeine.coumaric acid. Dissolution studies were performed in aqueous media at room temperature. All of the cocrystals decreased the solubility of caffeine with the highest being a 278 fold decrease in the solubility of caffeine. Analysis of melting point, crystal packing efficiency and solubility of cocrystal former with solubility was also done to determine if they influenced the solubility. Presented herein are the results of the analyses. It was seen that solubility of the cocrystal former had no effect on the decrease in cocrystal solubility. Moreover melting point and solubility of the cocrystal could not be correlated probably due to the variability in the cocrystal formers. Crystal packing efficiency though did not show a high correlation with solubility but it was seen that highest solubility achieved by pure caffeine achieved the lowest crystal packing efficiency and vice versa suggesting its role in cocrystal solubility. Pentoxifylline is contraindicated for its use in autism. But owing to high solubility of the drug, a less soluble form of the drug would help in decreasing the half life and thereby help in forming a sustained form of the drug by modifying the inherent solubility of the API. Here, novel cocrystals of Pentoxifylline are presented with varying solubilities with respect to the API. The pharmaceutical cocrystals used herein include: pentoxifylline.benzoic acid, pentoxifylline.1-hydroxy-2-napthoic acid, pentoxifylline.salicylic acid, pentoxifylline.gallic acid, pentoxifylline. salicylamide, pentoxifylline.coumaric acid, pentoxifylline.caffeic acid and pentoxifylline.catechin hydrate. Dissolution studies were also performed in aqueous media at room temperature. All of the cocrystals decreased the solubility of Pentoxifylline with the highest being a 99 fold decrease in the solubility with pentoxifylline.coumaric acid. On analyzing melting point, crystal packing efficiency and relation of solubility of cocrystal former with solubility of cocrystal, as was done in the case of caffeine, the parameters showed no effect on solubility of the cocrystal.
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Thakur, Shravan Singh. "Introduction to Pharmaceutical Thermal Analysis: A Teaching Tool." Cleveland State University / OhioLINK, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=csu1316880806.

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Ye, Zhu Yi Fan. "Deep learning for pharmaceutical formulation prediction." Thesis, University of Macau, 2018. http://umaclib3.umac.mo/record=b3952123.

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Sander, John Roy George. "Expansions of supramolecular chemistry: nanocrystals, pharmaceutical cocrystals, imaging, and decorated olefins." Diss., University of Iowa, 2012. https://ir.uiowa.edu/etd/3527.

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Crystal engineering has matured into a design-driven field based on the exploitation of reliable interactions between the functional groups of molecules so as to achieve desired properties. The utility of crystal engineering has been realized in a breadth of fields and, as a microcosm of crystal engineering, this thesis will explore the application of crystal engineering in the pharmaceutical sciences, nanotechnology, synthetic chemistry, materials science, and biomedical imaging. As the trend in drug development continues to skew towards molecules with poor aqueous solubility the ability improve the physicochemical properties of a pharmaceutical agent, especially via non-covalent means, has become crucial. One method to impart improved physiochemical properties to pharmaceutical agents is through cocrystallization. A portion of this thesis will focus on the design-driven development of pharmaceutical cocrystals so as to impart improved mechanical properties to acetaminophen. As part of our investigation, we observed unexpected intermolecular interactions between the constituents of our cocrystals, which will contribute to the continued development of crystal engineering. In addition, we are interested in developing a methodology for the reliable fabrication of organic nanocrystals based on multi-component solids. Whereas the field of inorganic nanocrystals has blossomed, organic nanocrystals have remained largely underdeveloped. To expand the field of organic nanocrystals we turned to the synthesis of pharmaceutical nano-cocrystals. Specifically, we determined a sonochemical approach combined with multiple solvents and a surfactant could effectively synthesize pharmaceutical nano-cocrystals. As part of our desire to synthesize complex, multi-component, organic nanocrystals we also investigated the ability of a sonochemical approach to synthesize host-guest nanocrystals. In particular, the results demonstrated that sonochemistry successfully fabricates nano- and micrometer sized crystals of a host-guest solid and affords rhombic-dodecahedral crystals of a hollow topology. This thesis will also examine [2+2] photodimerizations in the solid-state. Previous work has successfully established the application of a template-directed solid-state approach to the photodimerization of olefins in the solid-state. However, these studies have largely focused on the reactivity of symmetric bipyridines. Thus, we have expanded the functional group diversity associated with [2+2] photodimerizations to include the cyano moiety. We have shown the template approach successfully aligns our targeted cyano-substituted olefins to enable photodimerizations in the solid-state. In addition, we have investigated the ability to synthesize cocrystals based on iodinated contrast agents. We believe the cocrystal approach could afford contrast agents with tailored properties based on the selected cocrystal former. The results of our investigation include five cocrystals and five salts composed of iodinated contrast agents. The results help to establish a knowledge base to be exploited in the design of future contrast agent based cocrystals with tailored properties.
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Williams, Brett H. "Design and synthesis of 3-[N-(cyclopropylmethyl) amino]-7-(methoxy or hydroxy)-2, 2-dimethyl-1-tetralone analogs as potential opioid receptor antagonists." Scholarly Commons, 2004. https://scholarlycommons.pacific.edu/uop_etds/591.

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A series of 3-aminotetralins were synthesized as potential opioid antagonists. Each proposed target compound was based on a 3-(mono- or dialkylamino )-7 -(hydroxy or methoxy)-2, 2-dimethyl-1-tetralone parent structure. Three synthetic schemes were developed utilizing the common intermediate, ethyl3-benzylamino-2, 2-dimethyl-4-(4- methoxyphenyl)butyrate 3. In Scheme I, compound 3 was modified through a series of six steps to obtain 3-(N-methyl-N-cyclopropanecarboxamido )-7 -methoxy-2, 2-dimethyl- 1-hydroxy-1-phenyltetralin (9). To carry out further synthetic steps on the intermediate 9 required the reduction of the amide function, which proved to be problematic in terms of product isolation. Scheme II was a four-step procedure, which utilized the intermediate ethyl 3- amino-2, 2 dimethyl-4-(4-methoxyphenyl)butyrate (4), also utilized in Scheme I. Ester hydrolysis of the amino ester 4 produced the amino acid 12. Internal cyclization of 12 yielded the key intermediate, 3-amino-7 -methoxy-2, 2-dimethyl-1-tetralone (13). TheNalkylation step was carried out on 13 and this yielded the target compounds, 3-[N- ( cyclopropylmethyl)amino ]- and 3-[N, N-( dicyclopropylmethyl)amino ]-7 -methoxy-2, 2- dimethyl-1-tetralone (14, 15). Subsequently, compounds 14 and 15 were 0-demethylated to obtain the respective target compounds, 3-[N-(cyclopropylmethyl)amino]- and 3-[N, N-(dicyclopropylmethyl)amino ]-7-hydroxy-2, 2-dimethyl-1-tetralone (16, 17). Scheme III was an alternate synthetic route to obtain the target compounds 3-[Nmethyl- N-( cyclopropylmethyl)amino ]-2, 2-dimethyl-7-(hydroxy or methoxy)-1-hydroxy- 1-phenyltetralin (10, 11) without the amide reduction step required in Scheme I. The intermediate 3 was N-methylated to form the 3-N-methyl-N-benzylamino ester 18 by the Eschweiler-Clarke procedure. Compound 18 was converted through a series of four steps to obtain 3-[ N-methyl-N-( cyclopropylmethyl)amino ]-7 -methoxy-2, 2-dimethyl-1- tetralone (22), a target compound which was 0-demethylated to obtain compound 23, the 7-0H analog. The mono- and dialkylated 3-aminotetralins were synthesized and confirmed for purity and correct molecular formula by utilizing 1H NMR, 13C NMR, mass spectrometry, and elemental analysis. The target compounds 14, 15, 16, 17,22 and 23 were converted to their salts and are being analyzed for opioid-related activity in receptor binding assays.
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Sun, Hongzhe. "Biological chemistry of bismuth drugs." Thesis, Birkbeck (University of London), 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.244018.

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Books on the topic "Pharmaceutical chemistry"

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Roth, Hermann J. Pharmaceutical chemistry. Chichester: Ellis Horwood, 1988.

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Shioiri, Takayuki, Kunisuke Izawa, and Toshiro Konoike, eds. Pharmaceutical Process Chemistry. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA, 2010. http://dx.doi.org/10.1002/9783527633678.

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B, Stenlake J., ed. Practical pharmaceutical chemistry. 4th ed. London: Athlone Press, 1988.

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Shioiri, Takayuki, Kunisuke Izawa, and Toshiro Konoike. Pharmaceutical process chemistry. Weinheim, Germany: Wiley-VCH, 2011.

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1920-, Beckett A. H., and Stenlake J. B, eds. Practical pharmaceutical chemistry. 4th ed. London: Athlone, 1988.

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Cairns, Donald. Essentials of pharmaceutical chemistry. 3rd ed. London: Pharmaceutical Press, 2008.

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Discher, Clarence A. Modern inorganic pharmaceutical chemistry. 2nd ed. Prospect Heights, Ill: Waveland Press, 1985.

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Gareth, Thomas. Medicinal chemistry. 2nd ed. Chichester: John Wiley, 2007.

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Gareth, Thomas. Medicinal chemistry. 2nd ed. Chichester: John Wiley, 2007.

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Gareth, Thomas. Medicinal chemistry. 2nd ed. Chichester: John Wiley, 2007.

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Book chapters on the topic "Pharmaceutical chemistry"

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Radhika, Sankaran, Mohan Neetha, and Gopinathan Anilkumar. "Green in Pharmaceutical Chemistry." In Green Organic Reactions, 131–47. Singapore: Springer Singapore, 2021. http://dx.doi.org/10.1007/978-981-33-6897-2_8.

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Al-Worafi, Yaser Mohammed, Long Chiau Ming, Abdullah Ahmed Dhabali, and Abdulkareem Mohammed Al-Shami. "Simulation for Pharmaceutical Chemistry." In Comprehensive Healthcare Simulation: Pharmacy Education, Practice and Research, 75–80. Cham: Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-33761-1_11.

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Chenier, Philip J. "The Pharmaceutical Industry." In Survey of Industrial Chemistry, 417–59. Boston, MA: Springer US, 2002. http://dx.doi.org/10.1007/978-1-4615-0603-4_23.

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Karpf, Martin. "From Milligrams to Tons: The Importance of Synthesis and Process Research in the Development of New Drugs." In Pharmaceutical Process Chemistry, 1–37. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA, 2010. http://dx.doi.org/10.1002/9783527633678.ch1.

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Takahashi, Kazuhiko, and Mitsuharu Hanada. "Process Development of Amrubicin Hydrochloride, an Anthracycline Anticancer Drug." In Pharmaceutical Process Chemistry, 207–20. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA, 2010. http://dx.doi.org/10.1002/9783527633678.ch10.

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Konoike, Toshiro, and Sumio Shimizu. "Process Development of HIV Integrase Inhibitor S-1360." In Pharmaceutical Process Chemistry, 221–38. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA, 2010. http://dx.doi.org/10.1002/9783527633678.ch11.

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Inaba, Takashi. "An Efficient Synthesis of the Protein Kinase Cβ Inhibitor JTT-010." In Pharmaceutical Process Chemistry, 239–55. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA, 2010. http://dx.doi.org/10.1002/9783527633678.ch12.

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Abe, Takao, and Masataka Kitamura. "Process Development of Oral Carbapenem Tebipenem Pivoxil, TBPM-PI." In Pharmaceutical Process Chemistry, 257–72. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA, 2010. http://dx.doi.org/10.1002/9783527633678.ch13.

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Liu, Delong, and Wanbin Zhang. "Some Progress in Organic Synthesis of Pharmaceuticals in China." In Pharmaceutical Process Chemistry, 273–302. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA, 2010. http://dx.doi.org/10.1002/9783527633678.ch14.

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Wells, Andrew S. "The Use of Continuous Processing to Make AZD 4407 Intermediates." In Pharmaceutical Process Chemistry, 303–19. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co. KGaA, 2010. http://dx.doi.org/10.1002/9783527633678.ch15.

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Conference papers on the topic "Pharmaceutical chemistry"

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Van der Vorst, G., W. Aelterman, P. Van Broeck, S. Walraedt, K. Schaerlaekens, P. Stouthuyzen, H. Van Langenhove, and J. Dewulf. "Comparison of two pharmaceutical production processes using different eco-efficiency measuring methods." In SUSTAINABLE CHEMISTRY 2011. Southampton, UK: WIT Press, 2011. http://dx.doi.org/10.2495/chem110021.

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Fernandez-Suarez, Miryam, Eduardo Garcia-Egido, Mickael Montembault, Maria J. Chapela, and Stephanie Y. F. Wong-Hawkes. "The Development of Integrated Microfluidic Chemistry Platforms for Lead Optimisation in the Pharmaceutical Industry." In ASME 4th International Conference on Nanochannels, Microchannels, and Minichannels. ASMEDC, 2006. http://dx.doi.org/10.1115/icnmm2006-96058.

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During the last decade, GlaxoSmithKline Pharmaceuticals (GSK) has carried out much of the seminal work in the area of micro fluidics and micro flow assay for lead optimisation. It has pioneered and built an in-house micro fluidic system for drug discovery. The huge and diverse advantages of this approach come from its miniaturised nature and its scale, which makes it easily automatable. As a result of its miniaturised nature it allows for greater control over heat and mass transfer, along with lower consumption of reagents (both chemical and biological) and solvents, less waste generation and decreased exposure to potentially toxic materials. But for a pharmaceutical company, the main advantage of this technology is the capability of coupling a fast microfluidic chemistry generator with a modern compatible miniaturised screening technique to generate instant biological information (i.e. the assay results) in “real time” that can be used to refine the chemistry (closing the feedback loop) and therefore allowing for a much faster lead optimisation. We will review some of the efforts within GSK towards this pioneering work in the development of miniaturised chemistry platforms capable of performing multiple functions such as synthesis, separation, quantification and screening.
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Ibrahem, Luma Ismail, and Qabas Naji Rashid. "Spectrophotometric determination of nystatin in its pharmaceutical preparations." In International Conference of Chemistry and Petrochemical Techniques (ICCPT). AIP Publishing, 2022. http://dx.doi.org/10.1063/5.0094147.

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Pate, Brooks, Channing West, Reilly Sonstrom, Haley Scolati, Kevin Mayer, and Martin Holdren. "CHEMICAL ANALYSIS CHALLENGES IN PHARMACEUTICAL CHEMISTRY AND UNDERGRADUATE PHYSICAL CHEMISTRY LABORATORY PROJECTS USING ROTATIONAL SPECTROSCOPY." In 2020 International Symposium on Molecular Spectroscopy. Urbana, Illinois: University of Illinois at Urbana-Champaign, 2020. http://dx.doi.org/10.15278/isms.2020.tb06.

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Maher, Sarah Arkan, and Qabas Naji Rashid. "Determination of metronidazole in pure and pharmaceutical preparations forms." In International Conference of Chemistry and Petrochemical Techniques (ICCPT). AIP Publishing, 2022. http://dx.doi.org/10.1063/5.0094369.

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Torrens, Francisco, and Gloria Castellano. "Fractal Dimension of Mucoadhesive Polymer Hyaluronan for Pharmaceutical Formulations." In The 16th International Electronic Conference on Synthetic Organic Chemistry. Basel, Switzerland: MDPI, 2012. http://dx.doi.org/10.3390/ecsoc-16-01085.

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Ziyatdinova, Guzel, Liliya Gimadutdinova, and Tatyana Antonova. "Novel voltammetric approaches for lipoic acid quantification in pharmaceutical dosage forms." In 7th International Electronic Conference on Medicinal Chemistry. Basel, Switzerland: MDPI, 2021. http://dx.doi.org/10.3390/ecmc2021-11399.

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Ratnawati, Enjarlis, and Slamet. "Combination of ozonation and photocatalysis for pharmaceutical wastewater treatment." In PROCEEDINGS OF THE 3RD INTERNATIONAL SYMPOSIUM ON APPLIED CHEMISTRY 2017. Author(s), 2017. http://dx.doi.org/10.1063/1.5011876.

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Silva-Reis, Sara C., Ivo E. Sampaio-Dias, Xerardo García-Mera, and José E. Rodríguez-Borges. "Rescuing of neuroprotective peptides by chemical conjugation with lipophilic active pharmaceutical ingredients." In 6th International Electronic Conference on Medicinal Chemistry. Basel, Switzerland: MDPI, 2020. http://dx.doi.org/10.3390/ecmc2020-07484.

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Tulegenova, G. A., A. B. Sagynbazarova, and K. SH Urasgaliev. "A lecture together as an innovative method in teaching toxicological chemistry." In General question of world science. Наука России, 2021. http://dx.doi.org/10.18411/gq-31-03-2021-43.

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The article discusses the lecture method, together in the teaching of toxicological chemistry at the Department of Pharmaceutical Disciplines, which provides knowledge, the formation of skills and development of the students' value system, professional skills and competencies.
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Reports on the topic "Pharmaceutical chemistry"

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Kolodziejczyk, Bart. Emergence of Quantum Computing Technologies in Automotive Applications: Opportunities and Future Use Cases. 400 Commonwealth Drive, Warrendale, PA, United States: SAE International, April 2024. http://dx.doi.org/10.4271/epr2024008.

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<div class="section abstract"><div class="htmlview paragraph">Quantum computing and its applications are emerging rapidly, driving excitement and extensive interest across all industry sectors, from finance to pharmaceuticals. The automotive industry is no different. Quantum computing can bring significant advantages to the way we commute, whether through the development of new materials and catalysts using quantum chemistry or improved route optimization. Quantum computing may be as important as the invention of driverless vehicles.</div><div class="htmlview paragraph"><b>Emergence of Quantum Computing Technologies in Automotive Applications: Opportunities and Future Use Cases</b> attempts to explain quantum technology and its various advantages for the automotive industry. While many of the applications presented are still nascent, they may become mainstream in a decade or so.</div><div class="htmlview paragraph"><a href="https://www.sae.org/publications/edge-research-reports" target="_blank">Click here to access the full SAE EDGE</a><sup>TM</sup><a href="https://www.sae.org/publications/edge-research-reports" target="_blank"> Research Report portfolio.</a></div></div>
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