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Journal articles on the topic 'Phae display'

Author: Grafiati

Published: 4 June 2021

Last updated: 2 February 2022

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1

Wilson, Dan R., and B. Brett Finlay. "Phage display: applications, innovations, and issues in phage and host biology." Canadian Journal of Microbiology 44, no. 4 (April 1, 1998): 313–29. http://dx.doi.org/10.1139/w98-015.

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In the 7 years since the first publications describing phage-displayed peptide libraries, phage display has been successfully employed in a variety of research. Innovations in vector design and methods to identify target clones account for much of this success. At the same time, not all ventures have been entirely successful and it appears that phage and host biology play important roles in this. A key issue concerns the role played by a displayed peptide or protein in its successful expression and incorporation into virions. While few studies have examined these issues specifically in context

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Popovych, O. M., I. M. Budzulyak, V. O. Kotsyubynsky, O. V. Popovych, B. I. Rachiy, R. V. Ilnytskyi, and L. S. Yablon. "Methods of obtaining nickel molybdates and composites of molybdate/carbon material for electrodes of hybrid supercapacitors (Review)." Physics and Chemistry of Solid State 21, no. 4 (December 30, 2020): 650–59. http://dx.doi.org/10.15330/pcss.21.4.650-659.

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Nickel molybdate due to its electronic configuration, stable crystalline framework, oxidation-reduction behavior displays perfect physical and chemical properties and rather high electrical conductivity that altogether lets the material display high total capacity. The research work classified modern methods of obtaining nickel molybdates and composites with carbon material on their basis. We have analyzed the fundamental stages of hydrothermal, microwave synthesis, ultrasonic dispersion, mechano-chemical, sol-gel method, and chemical precipitation method. The influence of different synthesis

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3

Cress, Jeffrey D., Lawrence J. Hettinger, James A. Cunningham, Gary E. Riccio, Grant R. McMillan, and Michael W. Haas. "An Initial Evaluation of a Direct Vestibular Display in a Virtual Environment." Proceedings of the Human Factors and Ergonomics Society Annual Meeting 40, no. 22 (October 1996): 1131–35. http://dx.doi.org/10.1177/154193129604002205.

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The US Air Force Armstrong Laboratory's Human Interface Technology Branch is currently investigating the development and potential application of direct vestibular displays. The Electrical Vestibular Stimulus (EVS) technology described in this paper uses electrodes located behind the ears to deliver a low-level electrical current in the area of the eighth cranial nerve of the central nervous system to produce a compelling sensation of roll motion about the body's fore-aft axis. In this study, subjects experienced the EVS display while simultaneously observing a large field-of-view visual roll

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P. W. M. Tsang, P. W. M. Tsang, Y. T. Chow Y.-T. Chow, T. C. Poon T.-C. Poon, and and J. P. Liu and J.-P. Liu. "Generation and optical display of a binary-sampled phase-only hologram." Chinese Optics Letters 14, no. 1 (2016): 010004–10007. http://dx.doi.org/10.3788/col201614.010004.

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Chikaev, A. N., A. P. Rudometov, Yu A. Merkulyeva, and L. I. Karpenko. "Phage display as a tool for identifying HIV-1 broadly neutralizing antibodies." Vavilov Journal of Genetics and Breeding 25, no. 5 (September 10, 2021): 562–72. http://dx.doi.org/10.18699/vj21.063.

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Combinatorial biology methods offer a good solution for targeting interactions of specific molecules by a high-throughput screening and are widely used for drug development, diagnostics, identification of novel monoclonal antibodies, search for linear peptide mimetics of discontinuous epitopes for the development of immunogens or vaccine components. Among all currently available techniques, phage display remains one of the most popular approaches. Despite being a fairly old method, phage display is still widely used for studying protein-protein, peptide-protein and DNA-protein interactions due

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6

Smith, George P., and Valery A. Petrenko. "Phage Display." Chemical Reviews 97, no. 2 (April 1997): 391–410. http://dx.doi.org/10.1021/cr960065d.

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7

Burton, Dennis R. "Phage display." Immunotechnology 1, no. 2 (August 1995): 87–94. http://dx.doi.org/10.1016/1380-2933(95)00013-5.

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8

Brichta, J., M. Hnilova, and T. Viskovic. "generation of hapten-specific recombinant antibodies: antibody phage display technology: a review." Veterinární Medicína 50, No. 6 (March 28, 2012): 231–52. http://dx.doi.org/10.17221/5620-vetmed.

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Production of antibodies has been revolutionized by the development of modern molecular biology methods for the expression of recombinant DNA. Phage display technology represents one of the most powerful tools for production and selection of recombinant antibodies and has been recognized as a valuable alternative way for the preparation of antibodies of a desired specificity. In comparison to poly- and monoclonal antibodies, recombinant antibodies using the phage display technology can be prepared faster, in more automatic process and with reduced consumption of laboratory animals. This review

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Feng Zhou, Feng Zhou, Qionghua Wang Qionghua Wang, Di Wu Di Wu, and Jianpeng Cui Jianpeng Cui. "Polymer-stabilized blue phase liquid crystal display with slanted wall-shaped electrodes." Chinese Optics Letters 10, no. 2 (2012): 022301–22303. http://dx.doi.org/10.3788/col201210.022301.

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Sui, Xiaomeng, Zehao He, Hao Zhang, Liangcai Cao, Daping Chu, and Guofan Jin. "Spatiotemporal double-phase hologram for complex-amplitude holographic displays." Chinese Optics Letters 18, no. 10 (2020): 100901. http://dx.doi.org/10.3788/col202018.100901.

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11

Siripanthong, Sitthinon, Anchalee Techasen, Chanin Nantasenamat, Aijaz Ahmad Malik, Paiboon Sithithaworn, Chanvit Leelayuwat, and Amonrat Jumnainsong. "Production and characterization of antibody against Opisthorchis viverrini via phage display and molecular simulation." PLOS ONE 16, no. 3 (March 23, 2021): e0248887. http://dx.doi.org/10.1371/journal.pone.0248887.

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In this study, a key issue to be addressed is the safe disposal of hybridoma instability. Hybridoma technology was used to produce anti–O. viverrini monoclonal antibody. Previous studies have shown that antibody production via antibody phage display can sustain the hybridoma technique. This paper presents the utility of antibody phage display technology for producing the phage displayed KKU505 Fab fragment and using experiments in concomitant with molecular simulation for characterization. The phage displayed KKU505 Fab fragment and characterization were successfully carried out. The KKU505 hy

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Gillespie, James W., Liping Yang, Laura Maria De Plano, Murray A. Stackhouse, and Valery A. Petrenko. "Evolution of a Landscape Phage Library in a Mouse Xenograft Model of Human Breast Cancer." Viruses 11, no. 11 (October 26, 2019): 988. http://dx.doi.org/10.3390/v11110988.

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Peptide-displayed phage libraries are billion-clone collections of diverse chimeric bacteriophage particles, decorated by genetically fused peptides built from a random combination of natural amino acids. Studying the molecular evolution of peptide-displayed libraries in mammalian model systems, using in vivo phage display techniques, can provide invaluable knowledge about the underlying physiology of the vasculature system, allow recognition of organ- and tissue-specific networks of protein–protein interactions, and provide ligands for targeted diagnostics and therapeutics. Recently, we disco

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13

Park, Min. "Surface Display Technology for Biosensor Applications: A Review." Sensors 20, no. 10 (May 13, 2020): 2775. http://dx.doi.org/10.3390/s20102775.

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Surface display is a recombinant technology that expresses target proteins on cell membranes and can be applied to almost all types of biological entities from viruses to mammalian cells. This technique has been used for various biotechnical and biomedical applications such as drug screening, biocatalysts, library screening, quantitative assays, and biosensors. In this review, the use of surface display technology in biosensor applications is discussed. In detail, phage display, bacterial surface display of Gram-negative and Gram-positive bacteria, and eukaryotic yeast cell surface display sys

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14

Wittrup, K. Dane. "Phage on display." Trends in Biotechnology 17, no. 11 (November 1999): 423–24. http://dx.doi.org/10.1016/s0167-7799(99)01349-9.

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15

Ward, Robyn. "ANTIBODY PHAGE DISPLAY." Immunology & Cell Biology 80, no. 3 (June 2002): 316–17. http://dx.doi.org/10.1046/j.1440-1711.2002.01091.x.

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16

Huang, Jian, Ratmir Derda, and Yanxin Huang. "Phage Display Informatics." Computational and Mathematical Methods in Medicine 2013 (2013): 1–2. http://dx.doi.org/10.1155/2013/698395.

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17

Barbas, S. M., and C. F. Barbas. "Filamentous phage display." Fibrinolysis 8 (January 1994): 245–52. http://dx.doi.org/10.1016/0268-9499(94)90722-6.

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Nchinda, Godwin W., Nadia Al-Atoom, Mamie T. Coats, Jacqueline M. Cameron та Alain B. Waffo. "Uniqueness of RNA Coliphage Qβ Display System in Directed Evolutionary Biotechnology". Viruses 13, № 4 (27 березня 2021): 568. http://dx.doi.org/10.3390/v13040568.

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Phage display technology involves the surface genetic engineering of phages to expose desirable proteins or peptides whose gene sequences are packaged within phage genomes, thereby rendering direct linkage between genotype with phenotype feasible. This has resulted in phage display systems becoming invaluable components of directed evolutionary biotechnology. The M13 is a DNA phage display system which dominates this technology and usually involves selected proteins or peptides being displayed through surface engineering of its minor coat proteins. The displayed protein or peptide’s functional

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Одиноков, С. Б., М. В. Шишова, А. Ю. Жердев, Д. С. Лушников та В. В. Маркин. "Исследование механизма записи мультиплексных брэгговских дифракционных решеток с планарным вводом-выводом оптического излучения в стеклянных световодах". Оптика и спектроскопия 129, № 4 (2021): 427. http://dx.doi.org/10.21883/os.2021.04.50770.297-20.

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The article describes the recording of multiplex Bragg diffraction gratings for optical lightguide displays using an optical replication method with a phase mask. The lightguides in the experiment were made of photo-thermo-refractive glass. A photoresist relief-phase diffraction grating was used as a phase mask. Based on angle multiplexing, a compact augmented reality display was implemented.

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Otowski, W., and G. Lewińska. "Dielectric properties and molecular motions of liquid crystal molecules in 4-(2-methylbytyl)phenyl 4-(4-octylphenyl)benzoate liquid crystal having blue phase (CE8)." Materials Science-Poland 33, no. 2 (June 1, 2015): 418–29. http://dx.doi.org/10.1515/msp-2015-0044.

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AbstractBlue phase liquid crystals exhibit unique properties which are used in the new type of display. A blue-phase liquid crystal display was first presented commercially by Samsung in 2007. The blue-phase-three-color pixel display eliminates the need for color filters. This type of display uses blue-phase multi-component liquid crystal. Considering the one-component systems, it turns out that they are stable only in a very narrow range of temperatures between the isotropic and the chiral nematic phase (about 1 K). In 2005, a wide temperature range BP multi-component system was reported by r

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Qi, Huan, Mingliang Ma, Danyun Lai, and Sheng-ce Tao. "Phage display: an ideal platform for coupling protein to nucleic acid." Acta Biochimica et Biophysica Sinica 53, no. 4 (February 4, 2021): 389–99. http://dx.doi.org/10.1093/abbs/gmab006.

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Abstract Display technology, especially phage display technology, has been widely applied in many fields. The theoretical core of display technology is the physical linkage between the protein/peptide on the surface of a phage and the coding DNA sequence inside the same phage. Starting from phage-displayed peptide/protein/antibody libraries and taking advantage of the ever-growing power of next-generation sequencing (NGS) for DNA sequencing/decoding, rich protein-related information can easily be obtained in a high-throughput way. Based on this information, many scientific and clinical questio

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22

Dröge, Melloney J., Ykelien L. Boersma, Peter G. Braun, Robbert Jan Buining, Mattijs K. Julsing, Karin G. A. Selles, Jan Maarten van Dijl, and Wim J. Quax. "Phage Display of an Intracellular Carboxylesterase of Bacillus subtilis: Comparison of Sec and Tat Pathway Export Capabilities." Applied and Environmental Microbiology 72, no. 7 (July 2006): 4589–95. http://dx.doi.org/10.1128/aem.02750-05.

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ABSTRACT Using the phage display technology, a protein can be displayed at the surface of bacteriophages as a fusion to one of the phage coat proteins. Here we describe development of this method for fusion of an intracellular carboxylesterase of Bacillus subtilis to the phage minor coat protein g3p. The carboxylesterase gene was cloned in the g3p-based phagemid pCANTAB 5E upstream of the sequence encoding phage g3p and downstream of a signal peptide-encoding sequence. The phage-bound carboxylesterase was correctly folded and fully enzymatically active, as determined from hydrolysis of the nap

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23

Wen, Jianxin, and Kunpeng Yuan. "Phage Display Technology, Phage Display System, Antibody Library, Prospects and Challenges." Advances in Microbiology 11, no. 03 (2021): 181–89. http://dx.doi.org/10.4236/aim.2021.113013.

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24

Arza, Begoña, and Jordi Félez. "The Emerging Impact of Phage Display Technology in Thrombosis and Haemostasis." Thrombosis and Haemostasis 80, no. 09 (1998): 354–62. http://dx.doi.org/10.1055/s-0037-1615211.

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IntroducationThe phage display technology represents a powerful tool for protein and drug design because vast numbers of amino acid sequences can be rapidly explored. This review describes the origins of phage libraries, their evolution and more recent advances, including examples in the area of thrombosis and haemostasis, where the phage display approach has just begun to be used with great success.Phage display uses filamentous phages (E. coli specific phages with a filamentous shape that contain a single stranded closed circular molecule of DNA), such as M13 or fd, as vehicles for displayin

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Partha, Cok Gede Indra. "Design and Balancing Load Current in 3-Phase System Using Microcontroller ATMEGA 2560." International Journal of Engineering and Emerging Technology 2, no. 1 (September 23, 2017): 76. http://dx.doi.org/10.24843/ijeet.2017.v02.i01.p16.

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The design of balancing the load current on three-phase systems using a microcontroller ATMega 2560 is a tool that serves to reduce the power loss. Power loss due to the load current unbalance the current flows in the neutral phase on three-phase systems. Current flows in the neutral phase distribution transformer into a detriment to PT. PLN (Persero) for the power lost to the earth and can not be used by consumers. So that it will balanced the load current to reduce the value of neutral current. The tool is also equipped with a monitoring system that displays current magnitude of each phase i

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VÃ¯Â¿Â½lchez, Susana, Juliette Jacoby та David J. Ellar. "Display of Biologically Functional Insecticidal Toxin on the Surface of λ Phage". Applied and Environmental Microbiology 70, № 11 (листопад 2004): 6587–94. http://dx.doi.org/10.1128/aem.70.11.6587-6594.2004.

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ABSTRACT The successful use of Bacillus thuringiensis insecticidal toxins to control agricultural pests could be undermined by the evolution of insect resistance. Under selection pressure in the laboratory, a number of insects have gained resistance to the toxins, and several cases of resistance in the diamondback moth have been reported from the field. The use of protein engineering to develop novel toxins active against resistant insects could offer a solution to this problem. The display of proteins on the surface of phages has been shown to be a powerful technology to search for proteins w

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Dmitrieva, Maria D., Anna A. Voitova, Maya A. Dymova, Vladimir A. Richter, and Elena V. Kuligina. "Tumor-Targeting Peptides Search Strategy for the Delivery of Therapeutic and Diagnostic Molecules to Tumor Cells." International Journal of Molecular Sciences 22, no. 1 (December 30, 2020): 314. http://dx.doi.org/10.3390/ijms22010314.

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Background: The combination of the unique properties of cancer cells makes it possible to find specific ligands that interact directly with the tumor, and to conduct targeted tumor therapy. Phage display is one of the most common methods for searching for specific ligands. Bacteriophages display peptides, and the peptides themselves can be used as targeting molecules for the delivery of diagnostic and therapeutic agents. Phage display can be performed both in vitro and in vivo. Moreover, it is possible to carry out the phage display on cells pre-enriched for a certain tumor marker, for example

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Moreno, Ignacio, Claudio Iemmi, Andrés Márquez, Juan Campos, and María J. Yzuel. "Modulation light efficiency of diffractive lenses displayed in a restricted phase-mostly modulation display." Applied Optics 43, no. 34 (December 1, 2004): 6278. http://dx.doi.org/10.1364/ao.43.006278.

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Rao, Kakuturu V. N., Yi-Xun He, and Ramaswamy Kalyanasundaram. "Expression of a 28-Kilodalton Glutathione S-Transferase Antigen of Schistosoma mansoni on the Surface of Filamentous Phages and Evaluation of Its Vaccine Potential." Clinical Diagnostic Laboratory Immunology 10, no. 4 (July 2003): 536–41. http://dx.doi.org/10.1128/cdli.10.4.536-541.2003.

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ABSTRACT A cloning and expression system that allows display of proteins on the surface of filamentous phages was exploited to display a 28-kDa glutathione S-transferase (Sm28GST) antigen of the human parasite Schistosoma mansoni. The phage-displayed Sm28GST (pdGST) was immunoreactive and was recognized by immune sera, suggesting that the Sm28GST protein displayed on the surface of phages potentially maintains native conformation. Subsequent immunization studies showed that mice can develop high titers of antibodies against pdGST and do not require any additional adjuvant for immunization. Iso

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30

Kościelska, K., L. Kiczak, M. Kasztura, O. Wesołowska, and J. Otlewski. "Phage display of proteins." Acta Biochimica Polonica 45, no. 3 (September 30, 1998): 705–20. http://dx.doi.org/10.18388/abp.1998_4210.

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In recent years the phage display approach has become an increasingly popular method in protein research. This method enables the presentation of large peptide and protein libraries on the surface of phage particles from which molecules of desired functional property(ies) can be rapidly selected. The great advantage of this method is a direct linkage between an observed phenotype and encapsulated genotype, which allows fast determination of selected sequences. The phage display approach is a powerful tool in generating highly potent biomolecules, including: search for specific antibodies, dete

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31

Nybo, Kristie. "Phage display: Binding confirmation." BioTechniques 49, no. 5 (November 2010): 789–91. http://dx.doi.org/10.2144/000113537.

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32

Jacobsson, Karin, and Lars Frykberg. "Shotgun Phage Display Cloning." Combinatorial Chemistry & High Throughput Screening 4, no. 2 (April 10, 2012): 135–43. http://dx.doi.org/10.2174/1386207013331255.

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33

Kretzschmar, Titus, and Thomas von Rüden. "Antibody discovery: phage display." Current Opinion in Biotechnology 13, no. 6 (December 2002): 598–602. http://dx.doi.org/10.1016/s0958-1669(02)00380-4.

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Dunn, Ian S. "Phase display of proteins." Current Opinion in Biotechnology 7, no. 5 (October 1996): 547–53. http://dx.doi.org/10.1016/s0958-1669(96)80060-7.

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35

SMITH, G. P., and V. A. PETRENKO. "ChemInform Abstract: Phage Display." ChemInform 28, no. 27 (August 3, 2010): no. http://dx.doi.org/10.1002/chin.199727302.

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36

Ladner, Robert Charles. "Phage display and pharmacogenomics." Pharmacogenomics 1, no. 2 (May 2000): 199–202. http://dx.doi.org/10.1517/14622416.1.2.199.

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37

Sandman, Karen E., Jack S. Benner, and Christopher J. Noren. "Phage Display of Selenopeptides." Journal of the American Chemical Society 122, no. 5 (February 2000): 960–61. http://dx.doi.org/10.1021/ja992462m.

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38

Zhou, Yi Hua, Hong Lin He, Jun Qian, Qian Luo, and Tao Lin Ma. "Study on the Spectral Distribution Property of PDLC Films Color Display." Advanced Materials Research 881-883 (January 2014): 1105–8. http://dx.doi.org/10.4028/www.scientific.net/amr.881-883.1105.

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PDLC films are very useful materials and can apply in flexible displays, intelligent switchable windows, information storage and adaptive optical devices. In this paper we focus on its color display characteristic in reflective display and firstly we fabricated PDLC films by polymerization induced phase separation method and measured its transmissivity and spectral reflection curves of the printing ink layer and PDLC covered color by X-Rite DTP41 Spectrophotometer. From the result, it demonstrates that PDLC films show different optical transmission properties in long and short wavelength.

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Neubrech, Frank, Xiaoyang Duan, and Na Liu. "Dynamic plasmonic color generation enabled by functional materials." Science Advances 6, no. 36 (September 2020): eabc2709. http://dx.doi.org/10.1126/sciadv.abc2709.

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Displays are an indispensable medium to visually convey information in our daily life. Although conventional dye-based color displays have been rigorously advanced by world leading companies, critical issues still remain. For instance, color fading and wavelength-limited resolution restrict further developments. Plasmonic colors emerging from resonant interactions between light and metallic nanostructures can overcome these restrictions. With dynamic characteristics enabled by functional materials, dynamic plasmonic coloration may find a variety of applications in display technologies. In this

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Notoya, S., H. Takahashi, T. Okumura, and C. H. Nielsen. "Newly Automated EPMA with Phase Identification System." Microscopy and Microanalysis 7, S2 (August 2001): 980–81. http://dx.doi.org/10.1017/s143192760003097x.

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We have developed a new Electron Probe Microanalyzer (EPMA), JXA-8100/8200, with improved basic capabilities such as X-ray intensities of wavelength dispersive spectrometers (WDS), imaging functions, automated functions and analysis software. Fig. 1 shows the appearance of JXA-8200, WD/ED combined microanalyzer. in this session, we report mainly on the improved imaging functions, automated functions and analysis software.The JXA-8100/8200 is the first EPMA in the world to feature 1280 x 1024 pixels high resolution live scanning image display. Regarding scanning image, two or four different sig

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Chasteen, L., J. Ayriss, P. Pavlik, and A. R. M. Bradbury. "Eliminating helper phage from phage display." Nucleic Acids Research 34, no. 21 (November 6, 2006): e145-e145. http://dx.doi.org/10.1093/nar/gkl772.

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VERHAERT, Raymond M. D., Jan VAN DUIN, and Wim J. QUAX. "Processing and functional display of the 86 kDa heterodimeric penicillin G acylase on the surface of phage fd." Biochemical Journal 342, no. 2 (August 24, 1999): 415–22. http://dx.doi.org/10.1042/bj3420415.

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The large heterodimeric penicillin G acylase from Alcaligenes faecalis was displayed on the surface of phage fd. We fused the coding sequence (α subunit-internal peptide-β subunit) to the gene of a phage coat protein. A modified g3p signal sequence was used to direct the polypeptide to the periplasm. Here we show that a heterodimeric enzyme can be expressed as a fusion protein that matures to an active biocatalyst connected to the coat protein of phage fd, resulting in a phage to which the β-subunit is covalently linked and the α-subunit is non-covalently attached. The enzyme can be displayed

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Lobel, Leslie I., John P. Morseman, Xiangfei Zeng, Joyce W. Lustbader, Hao Chen, and F. C. Thomas Allnutt. "Development of a Fluorescence Based High Throughput Assay for Antagonists of the Human Chorionic Gonadotropin Receptor Extracellular Domain: Analysis of Peptide Inhibitors." Journal of Biomolecular Screening 6, no. 3 (June 2001): 151–58. http://dx.doi.org/10.1177/108705710100600305.

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A simple method for prompt fluorescent detection of inhibitors of human chorionic gonadotropin (hCG) binding to the extracellular domain of the human luteinizing hormone/chorionic gonadotropin (hLHICG) receptor was developed for high throughput screening (HTS). Construction and analysis of a recombinant phage that displays the extracellular binding domain of the hLH/CG receptor on its surface and specifically binds hCG was previously described. To facilitate the identification of molecules that disrupt the interaction of hCG with its receptor, a method for prompt fluorescent detection of these

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Ferreiro, Marcela, Azadé D. Petrosky, and Ariel L. Escobar. "Intracellular Ca2+ release underlies the development of phase 2 in mouse ventricular action potentials." American Journal of Physiology-Heart and Circulatory Physiology 302, no. 5 (March 1, 2012): H1160—H1172. http://dx.doi.org/10.1152/ajpheart.00524.2011.

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The ventricular action potential (AP) is characterized by a fast depolarizing phase followed by a repolarization that displays a second upstroke known as phase 2. This phase is generally not present in mouse ventricular myocytes. Thus we performed colocalized electrophysiological and optical recordings of APs in Langendorff-perfused mouse hearts founding a noticeable phase 2. Ryanodine as well as nifedipine reduced phase 2. Our hypothesis is that a depolarizing current activated by Ca2+ released from the sarcoplasmic reticulum (SR) rather than the “electrogenicity” of the L-type Ca2+ current i

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Arab, Atefeh, Rezvan Yazdian Robati, Jessica Nicastro, Roderick Slavcev, and Javad Behravan. "Phage-based Nanomedicines as New Immune Therapeutic Agents for Breast Cancer." Current Pharmaceutical Design 24, no. 11 (June 27, 2018): 1195–203. http://dx.doi.org/10.2174/1381612824666180327152117.

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Despite years of investigation, breast cancer remains a major cause of death worldwide. Phage display is a powerful molecular method in which peptide and protein libraries can be displayed via genetic fusions on the surface of phages. This approach has tremendous potential for biomedical applications and has already facilitated the discovery of specific antibodies, specific antigens, and peptides with potential roles in the diagnosis and treatment of malignancies including breast cancer. In this review, we discuss the new and the latest advancements in the applications of the phage display tec

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Woo, Kevin. "Signal Competition in Dynamic Visual Environments: Relative Conspicuousness of Social Displays in the Jacky Dragon (Amphibolurus muricatus)." Animal Behavior and Cognition 8, no. 3 (August 3, 2021): 415–45. http://dx.doi.org/10.26451/abc.08.03.07.2021.

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Selection for conspicuousness has been an important force on visual signal design. Although signal efficacy has been extensively studied in acoustic systems, few studies have examined this attribute in dynamic visual signals. Here, I simulated signal competition between Jacky lizards (Amphibolurus muricatus) by presenting the motor patterns (tail-flick, push-up body rock, and slow arm wave) in isolation that are typically used in social communication. Phase 1 used four digital video playback systems to present simultaneous animated display combinations on opposing monitors to a subject that wa

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Wang, Yicun, Shuohui Gao, Jiayin Lv, Yang Lin, Li Zhou, and Liying Han. "Phage Display Technology and its Applications in Cancer Immunotherapy." Anti-Cancer Agents in Medicinal Chemistry 19, no. 2 (May 31, 2019): 229–35. http://dx.doi.org/10.2174/1871520618666181029140814.

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Background:Phage display is an effective technology for generation and selection targeting protein for a variety of purpose, which is based on a direct linkage between the displayed protein and the DNA sequence encoding it and utilized in selecting peptides, improving peptides affinity and indicating protein-protein interactions. Phage particles displaying peptide have the potential to apply in the identification of cell-specific targeting molecules, identification of cancer cell surface biomarkers, identification anti-cancer peptide, and the design of peptide-based anticancer therapy.Method/R

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Fidopiastis, Cali, Christopher Fuhrman, Catherine Meyer, and Jannick Rolland. "Methodology for the Iterative Evaluation of Prototype Head-Mounted Displays in Virtual Environments: Visual Acuity Metrics." Presence: Teleoperators and Virtual Environments 14, no. 5 (October 2005): 550–62. http://dx.doi.org/10.1162/105474605774918697.

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Head-mounted display design is an iterative process. As such, a standardized user-centered assessment protocol of head-mounted performance during each phase of prototype development should be employed. In this paper, we first describe a methodology for assessing prototype head-mounted displays and virtual environments using visual performance metrics. We then present an application of the methodology using a prototype of a projection head-mounted display and the first module of our assessment: resolution visual acuity as a function of contrast. To evaluate the total system, we also used three

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Betza, Scott M., Katherina A. Jurewicz, David M. Neyens, Sara L. Riggs, James H. Abernathy, and Scott T. Reeves. "Anesthesia Maintenance and Vigilance." Proceedings of the Human Factors and Ergonomics Society Annual Meeting 60, no. 1 (September 2016): 608–12. http://dx.doi.org/10.1177/1541931213601139.

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Limited research has focused on vigilance during the maintenance phase of anesthesia work. The goal of this study was to identify anesthesia maintenance tasks and to identify the transitions between these tasks within the perspective of the vigilance paradigm. In this study, three bariatric surgeries were recorded and analyzed using a task categorization structure. Across the surgeries the primary anesthesia provider spent 71% of their time doing patient or display monitoring tasks. Task frequency and transition visualizations were generated to identify trends in the task switching. Transition

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Doeringer, Joseph A., and Neville Hogan. "Intermittency in Preplanned Elbow Movements Persists in the Absence of Visual Feedback." Journal of Neurophysiology 80, no. 4 (October 1, 1998): 1787–99. http://dx.doi.org/10.1152/jn.1998.80.4.1787.

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Doeringer, Joseph A. and Neville Hogan. Intermittency in preplanned elbow movements persists in the absence of visual feedback. J. Neurophysiol. 80: 1787–1799, 1998. It has been observed for nearly 100 years that visually guided human movements appear to be composed of submovements, intermittently executed overlapping segments. This paper presents experiments to investigate the pervasiveness of movement intermittency and, in particular, whether it is exclusively due to visual feedback. With and without visual feedback, human subjects were asked to 1) move with constant velocity and 2) draw ell

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