Journal articles on the topic 'PFGLMS'
To see the other types of publications on this topic, follow the link: PFGLMS.
Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles
Consult the top 50 journal articles for your research on the topic 'PFGLMS.'
Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.
You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.
Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.
1
Hoang, Nguyen Huy, Nguyen Thi Bao Tran, Nguyen Van Thuan, and Bui Hong Thuy. "ID: 1063 Isolation and characterization of female germline stem cell derived from porcine ovary." Biomedical Research and Therapy 4, S (September 5, 2017): 145. http://dx.doi.org/10.15419/bmrat.v4is.337.
Full textAbstract:
One of the most significant finding in stem cell area in the early 21st century is the founding of female germline stem cells (FGSCs). Establishment of FGSCs allowed new possibilities for the use of them in biotechnology and medicine. Hence, the purpose of this study was to establish, characterize the porcine female germline stem cells (pFGSCs) from porcine ovary. The result revealed the success in establishing pFGSCs from ovarian tissue. Most of the pFGSCs were round shape after in vitro culture, forming groups of cells that cluster around the ovarian cells colonies. Immunofluorescent analysis of pFGSCs showed that these cells expressed germ cell and stem cell markers such as: Vasa, Stella, c-kit and Oct4. After several weeks in in vitro culture, pFGSCs increased in number without the loss of proliferative potential. Our results suggested that pFGSCs isolated from adult mammalian ovary, under appropriate conditions, could undergo proliferation.
2
Lim, Junghwa, D. Channe Gowda, Gowdahalli Krishnegowda, and Shirley Luckhart. "Induction of Nitric Oxide Synthase in Anopheles stephensi by Plasmodium falciparum: Mechanism of Signaling and the Role of Parasite Glycosylphosphatidylinositols." Infection and Immunity 73, no. 5 (May 2005): 2778–89. http://dx.doi.org/10.1128/iai.73.5.2778-2789.2005.
Full textAbstract:
ABSTRACT Malaria parasite (Plasmodium spp.) infection in the mosquito Anopheles stephensi induces significant expression of A. stephensi nitric oxide synthase (AsNOS) in the midgut epithelium as early as 6 h postinfection and intermittently thereafter. This induction results in the synthesis of inflammatory levels of nitric oxide (NO) in the blood-filled midgut that adversely impact parasite development. In mammals, P. falciparum glycosylphosphatidylinositols (PfGPIs) can induce NOS expression in immune and endothelial cells and are sufficient to reproduce the major effects of parasite infection. These effects are mediated in part by mimicry of insulin signaling by PfGPIs. In this study, we demonstrate that PfGPIs can induce AsNOS expression in A. stephensi cells in vitro and in the midgut epithelium in vivo. Signaling by P. falciparum merozoites and PfGPIs is mediated through A. stephensi Akt/protein kinase B and a pathway involving DSOR1, a mitogen-activated protein kinase kinase, and an extracellular signal-regulated kinase. However, despite the involvement of kinases that are also associated with insulin signaling in A. stephensi cells, signaling by P. falciparum and by PfGPIs is distinctively different from signaling by insulin. Therefore, although mimicry of insulin by PfGPIs appears to be restricted to mammalian hosts of P. falciparum, the conservation of PfGPIs as a prominent parasite-derived signal of innate immunity can now be extended to include Anopheles mosquitoes, indicating that parasite signaling of innate immunity is conserved in mosquito and mammalian cells.
3
Akman-Anderson, Leyla, Martin Olivier, and Shirley Luckhart. "Induction of Nitric Oxide Synthase and Activation of Signaling Proteins in Anopheles Mosquitoes by the Malaria Pigment, Hemozoin." Infection and Immunity 75, no. 8 (May 25, 2007): 4012–19. http://dx.doi.org/10.1128/iai.00645-07.
Full textAbstract:
ABSTRACT Anopheles stephensi, a major vector for malaria parasite transmission, responds to Plasmodium infection by synthesis of inflammatory levels of nitric oxide (NO), which can limit parasite development in the midgut. We have previously shown that Plasmodium falciparum glycosylphosphatidylinositols (PfGPIs) can induce A. stephensi NO synthase (AsNOS) expression in the midgut epithelium in vivo in a manner similar to the manner in which cytokines and NO are induced by PfGPIs in mammalian cells. In mosquito cells, signaling by PfGPIs and P. falciparum merozoites is mediated through Akt/protein kinase B (Akt/PKB), the mitogen-activated protein kinase kinase DSOR1, and extracellular signal-regulated kinase (ERK). In mammalian cells, a second parasite factor, malaria pigment or hemozoin (Hz), signals NOS induction through ERK- and nuclear factor kappa B-dependent pathways and has been demonstrated to be a novel proinflammatory ligand for Toll-like receptor 9. In this study, we demonstrate that Hz can also induce AsNOS gene expression in immortalized A. stephensi and Anopheles gambiae cell lines in vitro and in A. stephensi midgut tissue in vivo. In mosquito cells, Hz signaling is mediated through transforming growth factor β-associated kinase 1, Akt/PKB, ERK, and atypical protein kinase C zeta/lambda. Our results show that Hz is a prominent parasite-derived signal for Anopheles and that signaling pathways activated by PfGPIs and Hz have both unique and shared components. Together with our previous findings, our data indicate that parasite signaling of innate immunity is conserved in mosquito and mammalian cells.
4
Bhat, Javaid Yousuf, Brahmanaspati Ganapathi Shastri, and Hemalatha Balaram. "Kinetic and biochemical characterization of Plasmodium falciparum GMP synthetase." Biochemical Journal 409, no. 1 (December 11, 2007): 263–73. http://dx.doi.org/10.1042/bj20070996.
Full textAbstract:
Plasmodium falciparum, the causative agent of the fatal form of malaria, synthesizes GMP primarily from IMP and, hence, needs active GMPS (GMP synthetase) for its survival. GMPS, a G-type amidotransferase, catalyses the amination of XMP to GMP with the reaction occurring in two domains, the GAT (glutamine amidotransferase) and ATPPase (ATP pyrophosphatase). The GAT domain hydrolyses glutamine to glutamate and ammonia, while the ATPPase domain catalyses the formation of the intermediate AMP-XMP from ATP and XMP. Co-ordination of activity across the two domains, achieved through channelling of ammonia from GAT to the effector domain, is the hallmark of amidotransferases. Our studies aimed at understanding the kinetic mechanism of PfGMPS (Plasmodium falciparum GMPS) indicated steady-state ordered binding of ATP followed by XMP to the ATPPase domain with glutamine binding in a random manner to the GAT domain. We attribute the irreversible, Ping Pong step seen in initial velocity kinetics to the release of glutamate before the attack of the adenyl-XMP intermediate by ammonia. Specific aspects of the overall kinetic mechanism of PfGMPS are different from that reported for the human and Escherichia coli enzymes. Unlike human GMPS, absence of tight co-ordination of activity across the two domains was evident in the parasite enzyme. Variations seen in the inhibition by nucleosides and nucleotide analogues between human GMPS and PfGMPS highlighted differences in ligand specificity that could serve as a basis for the design of specific inhibitors. The present study represents the first report on recombinant His-tagged GMPS from parasitic protozoa.
5
Steffanoni, Sara, Alberto Agazzi, Daniele Laszlo, Sarah Jane Liptrott, Mara Negri, Fedro Alessandro Peccatori, and Giovanni Martinelli. "Primary Female Genital Lymphoma: Prognostic and Therapeutic Considerations." Blood 112, no. 11 (November 16, 2008): 4941. http://dx.doi.org/10.1182/blood.v112.11.4941.4941.
Full textAbstract:
Abstract Primary Female Genital Lymphoma (PFGL) is very rare, representing 1.5% of all Non-Hodgkin’s Lymphomas (NHLs) and 0.5% of female genital malignant tumours; uterus is the main commonly genital site involved by NHL. Most PFGLs are B-cell lymphomas; usually they occur in 5th decade of life. Because of PFGL rarity, a standard treatment has not been identified yet. This is a retrospective study on 20 women with PFGL, treated at European Institute of Oncology. The median age was 52 yrs (range 30–79 yrs); at diagnosis 6 pts were asymptomatic, 11 reported pelvic symptoms and 3 B symptoms. According to the International Prognostic Index, 7 pts had low, 6 intermediate, 6 high risk and one pt not known. Eleven pts had uterine involvement, with a concomitant extension to vagina in 5 of them, ovary NHL was recognised in 4 pts, vaginal NHL in 4 pts and vulvar NHL in one pt. Diffuse large B-cell NHL (DLBCL) was diagnosed in 14 pts, marginal extranodal NHL in 3 pts and follicular in 3 pts. According to Ann Arbor staging system: 8 pts were in early stage (IE–IIE) and 12 pts in stage IVE; considering FIGO system: 11 pts were in early stage (I–II), 6 pts in stage III for regional lymph node involvement and 3 in stage IV for concomitant non-genital extranodal localization; 12 pts presented with bulky disease. At diagnosis no pts had bone marrow involvement. The diagnostic biopsy was performed by endoscopy in 13 pts and by ultrasound-guided in 2 pts, whereas 5 pts underwent laparotomy. One pt with vulva-limited marginal NHL did not receive any treatment until disease progression (PD) and transformation to DLBCL. Five pts underwent laparotomy and adjuvant chemotherapy (CT) alone (n=4) or in combination with radiotherapy (RT) (n=1); 14 pts received CT alone (n=8) or in combination with RT (n=6) as first line therapy. Anthracycline-containing CT was delivered to all pts with DLBCL (n=14) and to one pt with high grade follicular NHL, 12 of them received concurrent immunotherapy anti-CD20 (Rituximab). Central nervous system (CNS) chemo-prophylaxis with i.v. high dose methotrexate was delivered to 3 pts because of advanced or bulky disease. Two pts with follicular and 2 with marginal subtype received alkylating-containing CT alone (n=2) or with Rituximab (n=2). The Overall Response Rate (ORR) to first line therapy was 80%; the response did not improve by the addition of local treatment to CT. Three pts did not response to first line therapy: one with marginal NHL in stable disease did not receive any additional treatment because of asymptomatic disease; two with DLBCL in PD underwent salvage treatment with high dose CT and died in PD, concurrent intrathecal therapy was mandatory in one pt because of CNS relapse. Three pts with follicular NHL, in response to first line therapy, relapsed: one went on to receive maintenance Rituximab, one resulted refractory to different rescue CT regimens and died in PD, one underwent autologous bone marrow transplantation obtaining CR. After a median follow up of 51 months (range 11–164 months), 17 pts are still alive: 10 in CR and 7 in PR, 3 pts died in PD. The Overall Survival (OS) at 3 and 14 yrs was 84.8% and 42.4% respectively. According to the literature the most common histological subtype of PFGL occurred in our population was DLBCL and the most frequent genital site involved was uterus (55% of cases) [Lagoo et al. 2006]. An additional local treatment did not seem to give an advantage in terms of ORR, PFS and OS in comparison with systemic therapy alone, as stated by the literature [Signorelli et al. 2006]. Concerning the pts treated with anthracycline-containing CT with or without Rituximab (n=15), 8 pts (53%) and 5 pts (33%) achieved CR and PR respectively, 2 pts (13%) had a PD during treatment, only one pt in CR relapsed after 65 months from the first line therapy. After a median follow up of 27 months 12 pts (80%) are alive, 3 (20%) died in PD. The Response Rate and OS in the subgroup of pts that received anthracycline-containing CT resulted similar to those reported in the literature [Coiffier 2002]; therefore female genital involvement by NHL doesn’t seem to represent a negative prognostic factor.
6
Ishiyama, Aki, Masato Iwatsuki, Tsuyoshi Yamamoto, Hiromi Miura, Satoshi Ōmura, and Kazuhiko Otoguro. "Antimalarial tropones and their Plasmodium falciparum glyoxalase I (pfGLOI) inhibitory activity." Journal of Antibiotics 67, no. 7 (April 9, 2014): 545–47. http://dx.doi.org/10.1038/ja.2014.28.
Full text
7
Li, Jun-Fei, Xiao-Rong Zheng, Hong-Yan Zhang, Chang-Ming Shen, Guo-xin Shen, and Jian-Wei Jiang. "Effects of Sensitized Sorafenib with a Paeoniflorin and Geniposide Mixture on Liver Cancer via the NF-κB-HIF-2α-SerpinB3 Pathway." Evidence-Based Complementary and Alternative Medicine 2022 (October 15, 2022): 1–11. http://dx.doi.org/10.1155/2022/1911311.
Full textAbstract:
Purpose. This study focused on determining the anticancer effect of paeoniflorin and geniposide mixture (PFGS) combined with sorafenib (Sor) in hepatocellular carcinoma (HCC) and, in particular, whether PFGS increases the antitumor effect of Sor by modulating the NF-κB/HIF-2α/SerpinB3 pathway. Methods. The H22 hepatoma tumor-bearing mouse model was treated with PFGS, Sor, and a combination of the two drugs for 12 days. The effects of PFGS combined with Sor on tumor growth and apoptosis and the expression of NF-κB, HIF-2α, and SerpinB3 in tumor tissue were assessed. In addition, Sor-resistant hepatoma cells were treated with PFGS, Sor, and the combination of the two drugs in vitro. The effects of PFGS combined with Sor on cell proliferation and invasion and the protein expression of NF-κB p65, HIF-2α, and SerpinB3 were investigated. Results. PFGS combined with Sor treatment synergistically inhibited tumor growth in HCC tumor-bearing mice. Immunostaining showed that PFGS combined with Sor treatment significantly decreased the expression of Ki-67 and obviously induced apoptosis in the tumor compared with a single treatment. Similarly, PFGS combined with Sor treatment significantly downregulated the expression of NF-κB, HIF-2α, and SerpinB3 in the tumor compared with a single treatment. Additionally, PFGS combined with Sor markedly inhibited cell proliferation and invasion and activation of the NF-κB/HIF-2α/SerpinB3 pathway in Sor-resistant hepatoma cells compared with a single treatment. Conclusion. Our study demonstrated that PFGS synergistically increased the antiliver cancer effects of Sor by lowering activation of the NF-κB/HIF-2α/SerpinB3 pathway. These findings provided a scientific foundation for clinical studies using PFGS and Sor to treat liver cancer.
8
K. Singal, Sandhya, and Yagna Shukla. "Effect of Different Positions of Body in Measuring Grip Strength in Tennis Elbow." International Journal of Health Sciences and Research 12, no. 6 (June 20, 2022): 154–57. http://dx.doi.org/10.52403/ijhsr.20220620.
Full textAbstract:
Grip strength is taken as an important measure to find effect as well as affection in tennis elbow. Measuring pain free grip strength is (PFGS) an important outcome measure for Tennis Elbow (TE). The different positions of elbow give change in the value of PFGS. This study aims to examine effects of two different position of body on PFGS in tennis elbow patients. Aims: To find out better position for measuring PFGS in tennis elbow. Methods and Material: A cross sectional study done in the Physiotherapy department. Unilateral chronic tennis elbow patients were included in the study according to inclusion and exclusion criterias after getting written informed consent. Jammer hand held dynamometer was used to measure the PFGS. PFGS was measured in sitting position with elbow flexion 90° and supine lying position with elbow extension. Average of three trials was taken with rest of 1 minute in between. Results: On comparing both positions there is significant difference (p<0.05) found in PFGS measurements in male and female at 95% confidence limit. There is significant increased PFGS noted in sitting position with elbow flexion 90° than with supine lying position with elbow extension. Conclusions: There is higher comparable PFGS (6.6%) noted in sitting with elbow flexion 90° position than with supine lying with elbow extension position. So it is better to measure PFGS in sitting with elbow 90° flexion position. Key words: Pain free grip strength, supine lying, chair sitting, grip strength measurement, dynamometer.
9
Kosik, Pavol, Matus Durdik, Milan Skorvaga, Daniela Klimova, Dominika Kochanova, Zlatica Cerna, Miroslav Kubes, Marek Holop, and Igor Belyaev. "Induction of AML Preleukemic Fusion Genes in HSPCs and DNA Damage Response in Preleukemic Fusion Gene Positive Samples." Antioxidants 10, no. 3 (March 18, 2021): 481. http://dx.doi.org/10.3390/antiox10030481.
Full textAbstract:
Preleukemic fusion genes (PFGs) occurring after DNA damage in hematopoietic stem progenitor cells (HSPCs) in utero often represent the initial event in the development of childhood leukemia. While the incidence of PFGs characteristic for acute lymphoblastic leukemia (ALL) was relatively well examined by several research groups and estimated to be 1–5% in umbilical cord blood (UCB) of healthy newborns, PFGs that are relevant to acute myeloid leukemia (AML) were poorly investigated. Therefore, this study is focused on the estimation of the incidence of the most frequent AML PFGs in newborns. For the first time, this study considered the inducibility of AML PFGs in different subsets of UCB HSPCs by low-dose γ-rays and also compared endogenous DNA damage, apoptosis, and reactive oxygen species (ROS) level between UCB samples containing or lacking AML PFGs. We found that: (i) the incidence of AML PFGs in UCB was 3.19% for RUNX1-RUNX1T1, 3.19% for PML-RARα, and 1.17% for KMT2A-MLLT3, (ii) 50 cGy of γ-rays did not induce RUNX1-RUNX1T1, PML-RARα, or KMT2A-MLLT3 PFGs in different subsets of sorted and expanded HSPCs, and (iii) the AML PFG+ samples accumulated the same level of endogenous DNA damage, as measured by the γH2AX/53BP1 focus formation, and also the same ROS level, and apoptosis as compared to PFG− controls. Our study provides critical insights into the prevalence of AML PFGs in UCB of newborns, without the evidence of a specific HSPC population more susceptible for PFG formation after irradiation to low-dose γ-rays or increased amount of ROS, apoptosis and DNA damage.
10
Sivanerupan, S., J. L. Wilson, E. F. Gad, and N. T. K. Lam. "Drift Performance of Point Fixed Glass Façade Systems." Advances in Structural Engineering 17, no. 10 (November 2014): 1481–95. http://dx.doi.org/10.1260/1369-4332.17.10.1481.
Full textAbstract:
Glass façade systems in buildings are subject to racking actions caused by inter storey drifts from earthquakes and wind action. The performance of façade systems is dependent on the amount of imposed drift and the interaction of the glass panels with the façade structural support frames. There are two major concerns related to the glass façade system performance during and immediately after a seismic event; hazards to people from falling glass and the cost associated with building down time and repair. It was observed that earthquake damage to glass façade systems resulting from in-plane racking actions is increasingly common and yet there has been limited research published in this field. The research completed to date has mainly focused on traditional framed glass façade systems; however, the racking performance of point fixed glass façade system (PFGFS) is likely to be quite different. Therefore, the aim of the research presented in this paper is to assess the in-plane racking performance of PFGFS which is a façade system gaining popularity worldwide. Two unique full scale in-plane racking laboratory tests on typical PFGFS with different types of connections were conducted and specific racking mechanisms were identified. Sophisticated non-linear finite element models (FE models) were developed and benchmarked against experimental results with excellent correlation. Further detailed FE analyses were conducted to evaluate the individual drift contributions of each racking mechanism such as rigid body translation of the glass panels at the oversize holes for construction tolerance, spider arm rotation and spider arm deformation. It was found that most of the drift capacity is attributed to the rigid body translation at the oversize holes. In this paper, the laboratory test setup and the experimental results are discussed together with the confirmatory FE analysis results to assess the in-plane racking performance of the PFGFS.
11
Rosyida, Isnaini, and Suryono Suryono. "Coloring picture fuzzy graphs through their cuts and its computation." International Journal of Advances in Intelligent Informatics 7, no. 1 (March 31, 2021): 63. http://dx.doi.org/10.26555/ijain.v7i1.612.
Full textAbstract:
In a fuzzy set (FS), there is a concept of alpha-cuts of the FS for alpha in [0,1]. Further, this concept was extended into (alpha,delta)-cuts in an intuitionistic fuzzy set (IFS) for delta in [0,1]. One of the expansions of FS and IFS is the picture fuzzy set (PFS). Hence, the concept of (alpha,delta)-cuts was developed into (alpha,delta,beta)-cuts in a PFS where beta is an element of [0,1]. Since a picture fuzzy graph (PFG) consists of picture fuzzy vertex or edge sets or both of them, we have an idea to construct the notion of the (alpha,delta,beta)-cuts in a PFG. The steps used in this paper are developing theories and algorithms. The objectives in this research are to construct the concept of (alpha,delta,beta)-cuts in picture fuzzy graphs (PFGs), to construct the (alpha,delta,beta)-cuts coloring of PFGs, and to design an algorithm for finding the cut chromatic numbers of PFGs. The first result is a definition of the (alpha,delta,beta)-cut in picture fuzzy graphs (PFGs) where (alpha,delta,beta) are elements of a level set of the PFGs. Further, some properties of the cuts are proved. The second result is a concept of PFG coloring and the chromatic number of PFG based on the cuts. The third result is an algorithm to find the cuts and the chromatic numbers of PFGs. Finally, an evaluation of the algorithm is done through Matlab programming. This research could be used to solve some problems related to theories and applications of PFGs.
12
Liu, Tao, Chaodong Li, Chao Wang, Joel Weijia Lai, and Kang Hao Cheong. "A Simple-FSDT-Based Isogeometric Method for Piezoelectric Functionally Graded Plates." Mathematics 8, no. 12 (December 6, 2020): 2177. http://dx.doi.org/10.3390/math8122177.
Full textAbstract:
An efficient isogeometric analysis method (IGA) based on a simple first-order shear deformation theory is presented to study free vibration, static bending response, dynamic response, and active control of functionally graded plates (FGPs) integrated with piezoelectric layers. Based on the neutral surface, isogeometric finite element motion equations of piezoelectric functionally graded plates (PFGPs) are derived using the linear piezoelectric constitutive equation and Hamilton’s principle. The convergence and accuracy of the method for PFGPs with various mechanical and electrical boundary conditions have been investigated via free vibration analysis. In the dynamic analysis, both time-varying mechanical and electrical loads are involved. A closed-loop control method, including displacement feedback control and velocity feedback control, is applied to the static bending control and the dynamic vibration control analysis. The numerical results obtained are accurate and reliable through comparisons with various numerical and analytical examples.
13
Li, Zijing, Maowei Liang, Zhiyong Li, Pierre Mariotte, Xuze Tong, Jinghui Zhang, Lei Dong, et al. "Plant functional groups mediate effects of climate and soil factors on species richness and community biomass in grasslands of Mongolian Plateau." Journal of Plant Ecology 14, no. 4 (March 9, 2021): 679–91. http://dx.doi.org/10.1093/jpe/rtab021.
Full textAbstract:
Abstract Aims Functional group composition of a plant community is mainly driven by environmental factors and is one of the main determinants of grassland biodiversity and productivity. Therefore, it is important to understand the role of plant functional groups (PFGs) in mediating the impact of environmental conditions on ecosystem functions and biodiversity. Methods We measured plant biomass and species richness (SR) of grasslands in 65 sites on the Mongolian Plateau and classified 157 perennial herbaceous plants into two main PFGs (namely grasses and forbs). Using the random forest model and ordinary least squares regression, we identified that environmental factors (i.e. aridity index, soil total nitrogen [STN] and pH) were significantly related to the SR and aboveground biomass (AGB) of PFGs. We then used structural equation modeling to explore the relationship between the identified environmental factors and community SR and biomass, and the role of PFGs in driving this relationship. Important Findings We found that aridity index had unimodal relationships with both AGB and SR of the PFGs and the whole community. All SR and biomass metrics were significantly related to STN and pH. The relationship between aridity index and community biomass was mediated by an increase in the AGB of grasses. The influence of STN and pH on community SR was mainly due to their regulation in the SR of forbs. Our results indicate that community composition and the identity of the PFGs play a key role in linking environmental factors to ecosystem functioning.
14
Gjestvang, D., S. Siem, F. Zeiser, J. Randrup, R. Vogt, F. Bello-Garrote, L. A. Bernstein, et al. "The study of prompt fission γ rays at the Oslo Cyclotron Laboratory." EPJ Web of Conferences 256 (2021): 00005. http://dx.doi.org/10.1051/epjconf/202125600005.
Full textAbstract:
The study of prompt fission γ rays (PFGs) is crucial for understanding the energy and angular momentum distribution in fission, and over the last decade there has been an revived interest in this aspect of fission. We present the new experimental setup at the Oslo Cyclotron Laboratory for detecting PFGs resulting from charged particle-induced fission. Additionally, PFGs from the reaction 240Pu(d,pf) were measured in April 2018, and the fission gated proton-γ coincidence spectrum is shown. In order to explore the dependence of the PFG emission on the excitation energy and angular momentum of the compound nucleus, we plan several experiments where charged particle reactions are used to induce fission in various plutonium isotopes. The final results will be compared to predictions made by the Fission Reaction Event Yield Algorithm (FREYA) in an upcoming publication, to benchmark the current modelling of both the PFGs and the fission process.
15
Morgan, Mark, Terence Cosgrove, and Robert Richardson. "The diffusion of benzene in high silica zeolite ZSM5 studied by PFGNMR and QUENS." Colloids and Surfaces 36, no. 2 (January 1989): 209–19. http://dx.doi.org/10.1016/0166-6622(89)80239-2.
Full text
16
YU, GONG-XIN. "RULEMINER: A KNOWLEDGE SYSTEM FOR SUPPORTING HIGH-THROUGHPUT PROTEIN FUNCTION ANNOTATIONS." Journal of Bioinformatics and Computational Biology 02, no. 04 (December 2004): 595–617. http://dx.doi.org/10.1142/s0219720004000752.
Full textAbstract:
In this paper, we present RuleMiner, a knowledge system to facilitate a seamless integration of multi-sequence analysis tools and define profile-based rules for supporting high-throughput protein function annotations. This system consists of three essential components, Protein Function Groups (PFGs), PFG profiles and rules. The PFGs, established from an integrated analysis of current knowledge of protein functions from Swiss-Prot database and protein family-based sequence classifications, cover all possible cellular functions available in the database. The PFG profiles illustrate detailed protein features in the PFGs as in sequence conservations, the occurrences of sequence-based motifs, domains and species distributions. The rules, extracted from the PFG profiles, describe the clear relationships between these PFGs and all possible features. As a result, the RuleMiner is able to provide an enhanced capability for protein function analysis, such as results from the integrated sequence analysis tools for given proteins can be comparatively analyzed due to the clear feature-PFG relationships. Also, much needed guidance is readily available for such analysis. If the rules describe one-to-one (unique) relationships between the protein features and the PFGs, then these features can be utilized as unique functional identifiers and cellular functions of unknown proteins can be reliably determined. Otherwise, additional information has to be provided.
17
Ballut, Lionel, Sébastien Violot, Frédéric Galisson, Isabelle R. Gonçalves, Juliette Martin, Santosh Shivakumaraswamy, Loïc Carrique, Hemalatha Balaram, and Nushin Aghajari. "Tertiary and Quaternary Structure Organization in GMP Synthetases: Implications for Catalysis." Biomolecules 12, no. 7 (June 23, 2022): 871. http://dx.doi.org/10.3390/biom12070871.
Full textAbstract:
Glutamine amidotransferases, enzymes that transfer nitrogen from Gln to various cellular metabolites, are modular, with the amidotransferase (GATase) domain hydrolyzing Gln, generating ammonia and the acceptor domain catalyzing the addition of nitrogen onto its cognate substrate. GMP synthetase (GMPS), an enzyme in the de novo purine nucleotide biosynthetic pathway, is a glutamine amidotransferase that catalyzes the synthesis of GMP from XMP. The reaction involves activation of XMP though adenylation by ATP in the ATP pyrophosphatase (ATPPase) active site, followed by channeling and attack of NH3 generated in the GATase pocket. This complex chemistry entails co-ordination of activity across the active sites, allosteric activation of the GATase domain to modulate Gln hydrolysis and channeling of ammonia from the GATase to the acceptor active site. Functional GMPS dimers associate through the dimerization domain. The crystal structure of the Gln-bound complex of Plasmodium falciparum GMPS (PfGMPS) for the first time revealed large-scale domain rotation to be associated with catalysis and leading to the juxtaposition of two otherwise spatially distal cysteinyl (C113/C337) residues. In this manuscript, we report on an unusual structural variation in the crystal structure of the C89A/C113A PfGMPS double mutant, wherein a larger degree of domain rotation has led to the dissociation of the dimeric structure. Furthermore, we report a hitherto overlooked signature motif tightly related to catalysis.
18
Zhu, Liying, Yuanyuan Chen, Yawei Wang, Chunrong Wang, and Yuansong Wei. "Ecological assessment of water quality in an urban river replenished with reclaimed water: the phytoplankton functional groups approach." Environmental Research Communications 3, no. 11 (November 1, 2021): 115006. http://dx.doi.org/10.1088/2515-7620/ac3777.
Full textAbstract:
Abstract Comprehensive water quality assessment plays a vital role in decision making for the sustainable management of urban rivers, and thus the exploration of integrated ecological assessment methods for water quality has become a major requirement. This study assessed the water quality of the North Canal River on the basis of its ecological status using the phytoplankton functional groups (PFGs) approach. The river runs through the megacities of the Beijing-Tianjin-Hebei region in China, and is mainly replenished with reclaimed water. The results showed that the PFGs approach is much better for evaluating the water quality of urban rivers than the conventional physicochemical index method and phytoplankton diversity metrics, because the PFGs approach is more sensitive to the spatiotemporal variations in the water quality of urban rivers. The average Q r index, for ecological status estimation in rivers, based on the PFGs of the North Canal River was 3.30, indicating ‘good’ water quality. In the dry season, the dominant PFG upstream was group D (Cyclotella spp.), whereas the major downstream PFGs had changed to group Y (Glenodinium spp., Cryptomonas ovata, and Cryptomonas erosa) and W1 (Euglena spp. and Gonium pectoral). While the dominant PFG throughout the river changed to TB: Melosira spp. in the wet season. The Q r at each site was one to two grades lower during the wet season than the dry season, indicating that water quality was worse in the wet than the dry season.
19
Dinh Duc, Nguyen, and Pham Hong Cong. "Nonlinear thermo-mechanical dynamic analysis and vibration of higher order shear deformable piezoelectric functionally graded material sandwich plates resting on elastic foundations." Journal of Sandwich Structures & Materials 20, no. 2 (May 26, 2016): 191–218. http://dx.doi.org/10.1177/1099636216648488.
Full textAbstract:
Used the Reddy's higher-order shear deformation plate theory, the nonlinear dynamic analysis and vibration of imperfect functionally graded sandwich plates in thermal environment with piezoelectric actuators (PFGM) on elastic foundations subjected to a combination of electrical, damping loadings and temperature are investigated in this article. One of the salient features of this work is the consideration of temperature on the piezoelectric layer, and the material properties of the PFGM sandwich plates are assumed to be temperature-dependent. The governing equations are established based on the stress function, the Galerkin method, and the Runge–Kutta method. In the numerical results, the effects of geometrical parameters; material properties; imperfections; elastic foundations; electrical, thermal, and damping loads on the vibration and nonlinear dynamic response of the PFGM sandwich plates are discussed. The obtained natural frequencies are verified with the known results in the literature.
20
Kennedy, Anthony, Carla J. Long, Peter J. Hmel, Rickey Hicks, and Thomas J. Reid. "The association of dimethylsulfoxide and model membranes studied by pulse-field gradient NMR." Spectroscopy 18, no. 2 (2004): 265–69. http://dx.doi.org/10.1155/2004/814213.
Full textAbstract:
The use of dimethylsulfoxide (DMSO) as a cryoprotectant to reduce cellular injury during freezing is well known, however the intermolecular interactions between this amphiphilic molecule and biological membranes that form the basis of this protection are unknown. DMSO–dipalmitoylphosphatidylcholine (DPPC) vesicle interactions were investigated in pulsed-field gradient NMR (PFGNMR) experiments and spectra analysis allowed for the determination of self-diffusion coefficients for each species present. The mole fraction of DMSO associated with the DPPC vesicles was then calculated from the diffusion coefficients: the mole fraction increased from 14% to 42% as the membrane was heated from below to above the main phase transition temperature.
21
Qi, L., J. N. Wilson, M. Lebois, A. Al-Adili, A. Chatillon, D. Choudhury, A. Gatera, et al. "Prompt fission gamma-ray emission spectral data for 239Pu(n,f) using fast directional neutrons from the LICORNE neutron source." EPJ Web of Conferences 169 (2018): 00018. http://dx.doi.org/10.1051/epjconf/201816900018.
Full textAbstract:
Prompt fission gamma-ray spectra (PFGS) have been measured for the 239Pu(n,f) reaction using fast neutrons at Ēn=1.81 MeV produced by the LICORNE directional neutron source. The setup makes use of LaBr3 scintillation detectors and PARIS phoswich detectors to measure the emitted prompt fission gamma rays (PFG). The mean multiplicity, average total energy release per fission and average energy of photons are extracted from the unfolded PFGS. These new measurements provide complementary information to other recent work on thermal neutron induced fission of 239Pu and spontaneous fission of 252Cf.
22
Kärger, Jörg, and Hervé Jobic. "Comment on “The diffusion of benzene in high silica zeolite ZSM-5 studied by PFGNMR and QUENS”." Colloids and Surfaces 58, no. 1-2 (September 1991): 203–5. http://dx.doi.org/10.1016/0166-6622(91)80208-6.
Full text
23
Akram, Muhammad, and Sumera Naz. "Energy of Pythagorean Fuzzy Graphs with Applications." Mathematics 6, no. 8 (August 10, 2018): 136. http://dx.doi.org/10.3390/math6080136.
Full textAbstract:
Pythagorean fuzzy sets (PFSs), an extension of intuitionistic fuzzy sets (IFSs), inherit the duality property of IFSs and have a more powerful ability than IFSs to model the obscurity in practical decision-making problems. In this research study, we compute the energy and Laplacian energy of Pythagorean fuzzy graphs (PFGs) and Pythagorean fuzzy digraphs (PFDGs). Moreover, we derive the lower and upper bounds for the energy and Laplacian energy of PFGs. Finally, we present numerical examples, including the design of a satellite communication system and the evaluation of the schemes of reservoir operation to illustrate the applications of our proposed concepts in decision making.
24
Beshah, Kebede, Aslin Izmitli, Antony K. Van Dyk, John J. Rabasco, James Bohling, and Susan J. Fitzwater. "Diffusion-Weighted PFGNMR Study of Molecular Level Interactions of Loops and Direct Bridges of HEURs on Latex Particles." Macromolecules 46, no. 6 (March 12, 2013): 2216–27. http://dx.doi.org/10.1021/ma400114v.
Full text
25
Pham, Thanh Luu, Thi Hoang Yen Tran, and Thanh Thai Tran. "Factors affecting the seasonal succession of phytoplankton functional groups in a tropical floodplain reservoir in Vietnam." Journal of Water Supply: Research and Technology-Aqua 71, no. 3 (March 1, 2022): 401–14. http://dx.doi.org/10.2166/aqua.2022.110.
Full textAbstract:
Abstract Phytoplankton communities can be classified into different groups based on physiological, morphological, and ecological functions. In this study, the responses of phytoplankton functional groups (PFGs) to physicochemical variables and hydraulic regimes were investigated and used as ecological indicators in the Tri An Reservoir (TAR), a eutrophic tropical floodplain reservoir located in southern Vietnam. Altogether, 148 phytoplankton taxa were identified and assigned to 16 PFGs; the four predominant PFG groups were M (Microcystis spp.), MP (filamentous cyanobacteria: Oscillatoria spp., and some other diatoms: Gomphonema angustatum, Navicula sp.), J (green algae: Coelastrum spp., Cosmarium spp., Pediastrum spp., Scenedesmus spp., Staurastrum spp., Tetradesmus spp., Tetraëdron spp., and Xanthidium spp.), and P (Closterium spp., Aulacoseira granulata, Fragilaria spp., Pinnularia spp., and Desmidium baileyi). The average PFG biovolume ranged from 79.6 ± 20.2 to 230.1 ± 69.1 mg/L with M being the dominant group. The trophic state index (TSI) indicated that the water condition was light-eutrophic to hyper-eutrophic. It was found that the large water level fluctuation resulted in seasonal nutrient dynamics, with higher nutrient concentrations and higher turbidity during the low water level period and vice versa. The redundancy analysis (RDA) indicated that the nutrient concentrations, water level fluctuation, and mixing regimes were critical factors in the PFG selection in the TAR. Therefore, we assumed that water level fluctuation management coupled with biological competition have the potential to control toxic cyanobacteria in the TAR. In conclusion, the PFGs are suitable for examining the effects of environmental conditions on phytoplankton dynamics in tropical floodplain reservoirs, but their sensitivity to long-term changes in water quality and eutrophication requires further investigation.
26
Bashir, Shahida, Sundas Shahzadi, Ahmad N. Al-Kenani, and Muhammad Shabir. "Regular and Intra-Regular Semigroups in Terms of m-Polar Fuzzy Environment." Mathematics 9, no. 17 (August 24, 2021): 2031. http://dx.doi.org/10.3390/math9172031.
Full textAbstract:
The central objective of the proposed work in this research is to introduce the innovative concept of an m-polar fuzzy set (m-PFS) in semigroups, that is, the expansion of bipolar fuzzy set (BFS). Our main focus in this study is the generalization of some important results of BFSs to the results of m-PFSs. This paper provides some important results related to m-polar fuzzy subsemigroups (m-PFSSs), m-polar fuzzy ideals (m-PFIs), m-polar fuzzy generalized bi-ideals (m-PFGBIs), m-polar fuzzy bi-ideals (m-PFBIs), m-polar fuzzy quasi-ideals (m-PFQIs) and m-polar fuzzy interior ideals (m-PFIIs) in semigroups. This research paper shows that every m-PFBI of semigroups is the m-PFGBI of semigroups, but the converse may not be true. Furthermore this paper deals with several important properties of m-PFIs and characterizes regular and intra-regular semigroups by the properties of m-PFIs and m-PFBIs.
27
Lee, Chang-Shin, Chia-Hao Lin, Wan-Lun Hsieh, and Szu-Min Chiao. "Dependence of Peptide Self-Association on Intermolecular Interaction by PFGNMR in TFE Aqueous Solution: C-terminal Analogues of NPY as Model Peptides." Protein & Peptide Letters 18, no. 10 (October 1, 2011): 1065–71. http://dx.doi.org/10.2174/092986611796378710.
Full text
28
Di Giorgio, Lucas E., and Marcelo T. Piovan. "Dynamic reduced model and stochastic aspects for PFGM curved beams with variable curvature." Mechanics Research Communications 111 (January 2021): 103662. http://dx.doi.org/10.1016/j.mechrescom.2021.103662.
Full text
29
Njim, E. K. "Analytical and numerical flexural properties of polymeric porous functionally graded (PFGM) sandwich beams." Journal of Achievements in Materials and Manufacturing Engineering 110, no. 1 (January 1, 2022): 5–10. http://dx.doi.org/10.5604/01.3001.0015.7026.
Full text
30
Liu, Yan-Song, Marcus Gadau, Guo-Xue Zhang, Hao Liu, Fu-Chun Wang, Christopher Zaslawski, Tie Li, et al. "Acupuncture Treatment of Lateral Elbow Pain: A Nonrandomized Pilot Study." Evidence-Based Complementary and Alternative Medicine 2016 (2016): 1–8. http://dx.doi.org/10.1155/2016/8182071.
Full textAbstract:
In planning for a large-scale multicenter trial to evaluate the effect of acupuncture for the treatment of lateral elbow pain, a pilot study was conducted. This was a prospective, investigator- and patient-blinded, nonrandomized, placebo controlled trial. Subjects were evaluated at baseline, before fourth, seventh, and ninth treatment, and at a two-week posttreatment follow-up. The treatment group received unilateral acupuncture at LI 10 and LI 11 at the affected side with manual needle manipulation; the control group received sham-laser acupuncture at the same acupoints. Measures included (i) disabilities of the arm, shoulder, and hand (DASH) questionnaire, (ii) pain-free grip strength (PFGS), and (iii) a visual analogue scale (VAS) for pain. Significant differences in DASH score, PFGS, and VAS between treatment and control group were found at the ninth treatment (n=20for each group,P<0.05). Only DASH showed significant differences compared to the control for all the measurement time points after treatment commenced and appears to be a sensitive and appropriate primary outcome measure for the future multisite trial. Results from this pilot study provided relevant information about treatment efficacy, credibility of control treatment, and sensitivity of different outcome measures for the planning of the future trial.
31
Aldajah, S. H., O. O. Ajayi, G. R. Fenske, and Z. Xu. "Effect of Laser Surface Modifications Tribological Performance of 1080 Carbon Steel." Journal of Tribology 127, no. 3 (January 18, 2005): 596–604. http://dx.doi.org/10.1115/1.1924461.
Full textAbstract:
High-power laser surface treatments in the form of glazing, shock peening, cladding, and alloying can significantly affect material surface properties. In this paper, effects of laser glazing, laser shock peening, and their combination on the tribological behavior of 1080 carbon steel were investigated. Laser glazing is a process in which a high-power laser beam melts the top layer of the surface, followed by rapid cooling and resolidification. This results in a new surface layer microstructure and properties. Laser shock peening, on the other hand, is a mechanical process in which a laser generates pressure pulses on the surface of the metal, similar to shot peening. Five conditions were evaluated: untreated (baseline), laser shock peened only (PO), laser glazed only, laser glazed then shock peened last, and laser shock peened then glazed last (PFGL). In pin-on-disc testing, all laser-treated surfaces reduced dry friction when sliding against alumina, with the PFGL surface having maximum friction reduction of 43%, especially in the early stage of testing. Under lubricated conditions, all laser-treated surfaces except the PO sample lowered friction against alumina. Similarly, all glazed samples showed reduced wear by a factor of 2–3, whereas the peening alone did not change wear significantly. These tribological results are associated with changes in the near-surface microstructure and properties.
32
Cosgrove, T., M. Morgan, and R. M. Richardson. "Reply to comment by J. Kärger and H. Jobic on “The diffusion of benzene in high silica zeolite ZSM-5 studied by PFGNMR and QUENS”." Colloids and Surfaces 58, no. 1-2 (September 1991): 207–9. http://dx.doi.org/10.1016/0166-6622(91)80209-7.
Full text
33
Gutiérrez Mendoza, Iraima Sofía, Yamirle Mercedes Pérez Girón, and Antonio José Gutiérrez Mendoza. "Turismo Agroecológico: La integración entre lo presencialidad y la virtualidad." Revista Scientific 6, no. 19 (February 5, 2021): 349–65. http://dx.doi.org/10.29394/scientific.issn.2542-2987.2021.6.19.18.349-365.
Full textAbstract:
En un siglo XXI donde la educación universitaria atraviesa turbulencias, la Universidad Nacional Experimental de los Llanos Occidentales Ezequiel Zamora (UNELLEZ), Barinas, Venezuela, no queda excluida de los desafíos presentes. La actualidad tiene como arista la tecnología, modificando las formas de aprendizajes en los estudiantes siendo más visuales e interactivos. Es ahí, donde la revolución cognoscitiva por medio de la creación e innovación de formas llamativas entra en el terreno universitario para llamar la atención de los jóvenes hacia los contenidos de aprendizajes. La germinación de carreras nuevas hacia la virtualidad se hace necesaria, la presencia de un docente facilitador, el cual, mediante la interacción, transforme los conocimientos en preguntas para despertar el razonamiento en los estudiantes y ayudarlos a encontrar las respuestas a sus inquietudes. El objetivo del ensayo propone en ofrecer una reflexión sobre cambio significativo en los procesos enseñanza-aprendizaje virtual en el Programa de Formación de Grado Licenciatura en Turismo Agroecológico (PFGLTA), donde se aprende haciendo conllevando a un aprender aprendiendo, análisis, reflexión mediante las experiencias y las vivencias logrando familiarizarse con la adquisición de nociones virtuales mediante las herramientas digitales para palpar las realidades sensibles del entorno del Turismo Agroecológico, conquistar el interés en el campo turístico.
34
Fan, Fan, Saeid Sahmani, and Babak Safaei. "Isogeometric nonlinear oscillations of nonlocal strain gradient PFGM micro/nano-plates via NURBS-based formulation." Composite Structures 255 (January 2021): 112969. http://dx.doi.org/10.1016/j.compstruct.2020.112969.
Full text
35
Akram, Muhammad, Amna Habib, Farwa Ilyas, and Jawaria Dar. "Specific Types of Pythagorean Fuzzy Graphs and Application to Decision-Making." Mathematical and Computational Applications 23, no. 3 (August 23, 2018): 42. http://dx.doi.org/10.3390/mca23030042.
Full textAbstract:
The purpose of this research study is to present some new operations, including rejection, symmetric difference, residue product, and maximal product of Pythagorean fuzzy graphs (PFGs), and to explore some of their properties. This research article introduces certain notions, including intuitionistic fuzzy graphs of 3-type (IFGs3T), intuitionistic fuzzy graphs of 4-type (IFGs4T), and intuitionistic fuzzy graphs of n-type (IFGsnT), and proves that every IFG(n−1)T is an IFGnT (for n ≥ 2). Moreover, this study discusses the application of Pythagorean fuzzy graphs in decision making.
36
Lin, L., Y. K. Li, X. L. Xu, F. W. Zhang, Y. G. Du, S. L. Liu, X. W. Guo, and G. M. Cao. "Predicting parameters of degradation succession processes of Tibetan <i>Kobresia</i> grasslands." Solid Earth Discussions 7, no. 3 (August 6, 2015): 2185–211. http://dx.doi.org/10.5194/sed-7-2185-2015.
Full textAbstract:
Abstract. In the past two decades, increasing human activity (i.e., overgrazing) in the Tibetan Plateau has strongly influenced plant succession processes, resulting in the degradation of alpine grasslands. Therefore, it is necessary to diagnose the degree of degradation to enable implementation of appropriate management for sustainable exploitation and protection of alpine grasslands. Here, we investigated environmental factors and plant functional group quantity factors (PFGs) during the alpine grassland succession processes. Principal component analysis (PCA) was used to identify the parameters indicative of degradation. We divided the entire degradation process into six stages. PFG types shifted from rhizome bunch grasses to rhizome plexus and dense plexus grasses during the degradation process. Leguminosae and Gramineae plants were replaced by Sedges during the advanced stages of degradation. The PFGs were classified into two reaction groups: the grazing-sensitive group, containing Kobresia humilis Mey, and Gramineae and Leguminosae plants, and the grazing-insensitive group, containing Kobresia pygmaea Clarke. The first group was correlated with live root biomass in the surface soil (0–10 cm), whereas the second group was strongly correlated with mattic epipedon thickness and K. pygmaea characteristics. The degree of degradation of alpine meadows may be delineated by development of mattic epipedon and PFG composition. Thus, meadows could be easily graded and their use adjusted based on our scaling system, which would help prevent irreversible degradation of important grasslands. Because relatively few environmental factors are investigated, this approach can save time and labor to formulate a conservation management plan for degraded alpine meadows.
37
Gatera, Angélique, Alf Göök, Franz-Josef Hambsch, André Moens, Andreas Oberstedt, Stephan Oberstedt, Goedele Sibbens, David Vanleeuw, and Marzio Vidali. "Prompt fissionγ-ray characteristics from neutron-induced fission on 239Pu and the time-dependence of prompt-γray emission." EPJ Web of Conferences 169 (2018): 00003. http://dx.doi.org/10.1051/epjconf/201816900003.
Full textAbstract:
Recent years have seen an increased interest in prompt fission γ-ray (PFG) measurements motivated by a high priority request of the OECD/NEA for high precision data, mainly for the nuclear fuel isotopes 235U and 239Pu. Our group has conducted a PFG measurement campaign using state-of-the-art lanthanum halide detectors for all the main actinides to a precision better than 3%. The experiments were performed in a coincidence setup between a fission trigger and γ-ray detectors. The time-of-flight technique was used to discriminate photons, traveling at the speed of light, and prompt fission neutrons. For a full rejection of all neutrons below 20 MeV, the PFG time window should not be wider than a few nanoseconds. This window includes most PFG, provided that no isomeric states were populated during the de-excitation process. When isomeric states are populated, PFGs can still be emitted up to 1 yus after the instant of fission or later. To study these γ-rays, the detector response to neutrons had to be determined and a correction had to be applied to the γ-ray spectra. The latest results for PFG characteristics from the reaction 239Pu(nth,f) will be presented, together with an analysis of PFGs emitted up to 200 ns after fission in the spontaneous fission of 252Cf as well as for thermal-neutron induced fission on 235U and 239Pu. The results are compared with calculations in the framework of the Hauser-Feshbach Monte Carlo code CGMF and FIFRELIN.
38
Liu, Tao, Yafen Jiang, Shujun Li, Qingyun Liu, and Chao Wang. "Isogeometric Analysis for Active Control of Piezoelectric Functionally Graded Plates in Thermal Environment." Shock and Vibration 2021 (May 15, 2021): 1–18. http://dx.doi.org/10.1155/2021/5514476.
Full textAbstract:
An isogeometric analysis (IGA) method is proposed for investigating the active shape and vibration control of functionally graded plates (FGPs) with surface-bonded piezoelectric materials in a thermal environment. A simple first-order shear deformation theory (S-FSDT) with four variables is used to describe the displacement field of the plates. To ensure the investigation of smart piezoelectric structure in the thermal environment closer to the actual situation, a modified piezoelectric constitutive equation with consideration of the temperature effect of dielectric and piezoelectric strain coefficients is implemented to replace the traditional linear piezoelectric constitutive equation. Meanwhile, the neutral surface is adopted to avoid the stretching-bending coupling. The accuracy and effectiveness of the proposed S-FSDT-based IGA method are verified by comparing with several existing numerical examples. Then, the static bending and open-loop control of the plates under mechanical and thermal loads are further studied. Finally, the active control including static bending control and vibration control of piezoelectric functionally graded plates (PFGPs) is also investigated by using a displacement-velocity feedback control law.
39
Olbricht, C., O. T. Stein, J. Janicka, J. A. van Oijen, S. Wysocki, and A. M. Kempf. "LES of lifted flames in a gas turbine model combustor using top-hat filtered PFGM chemistry." Fuel 96 (June 2012): 100–107. http://dx.doi.org/10.1016/j.fuel.2012.01.018.
Full text
40
König, Gabriele M., and Anthony D. Wright. "Pulsed field gradient spectroscopy (PFGS): application to the structure elucidation of (+)-(10S)-10-bromo-β-chamigrene." Phytochemical Analysis 8, no. 4 (July 1997): 167–72. http://dx.doi.org/10.1002/(sici)1099-1565(199707)8:4<167::aid-pca349>3.0.co;2-w.
Full text
41
Rittler, Andreas, Fabian Proch, and Andreas M. Kempf. "LES of the Sydney piloted spray flame series with the PFGM/ATF approach and different sub-filter models." Combustion and Flame 162, no. 4 (April 2015): 1575–98. http://dx.doi.org/10.1016/j.combustflame.2014.11.025.
Full text
42
Wei, Yi-Gang. "Petrocodon ferrugineus (Gesneriaceae), a New Species from Guangxi, China." Novon: A Journal for Botanical Nomenclature 17, no. 1 (March 2007): 135–37. http://dx.doi.org/10.3417/1055-3177(2007)17[135:pfgans]2.0.co;2.
Full text
43
Rodin, Victor V., Stephan J. Ginthör, Matthias Bechmann, Hervé Desvaux, and Norbert Müller. "Spin noise gradient echoes." Magnetic Resonance 2, no. 2 (November 19, 2021): 827–34. http://dx.doi.org/10.5194/mr-2-827-2021.
Full textAbstract:
Abstract. Nuclear spin noise spectroscopy in the absence of radio frequency pulses was studied under the influence of pulsed field gradients (PFGs) on pure and mixed liquids. Under conditions where the radiation-damping-induced line broadening is smaller than the gradient-dependent inhomogeneous broadening, echo responses can be observed in difference spectra between experiments employing pulsed field gradient pairs of the same and opposite signs. These observed spin noise gradient echoes (SNGEs) were analyzed through a simple model to describe the effects of transient phenomena. Experiments performed on high-resolution nuclear magnetic resonance (NMR) probes demonstrate how refocused spin noise behaves and how it can be exploited to determine sample properties. In bulk liquids and their mixtures, transverse relaxation times and translational diffusion constants can be determined from SNGE spectra recorded following tailored sequences of magnetic field gradient pulses.
44
Ermenova, Batilya O., Tursunai G. Ibragimova, Dulat Sovetkhanuly, Bolatbek A. Duketayev, and Damir A. Bekbossynov. "A Health-improving and educational effect of gamified physical activities (Efecto educativo y de mejora de la salud de la actividad física del juego)." Retos, no. 39 (October 1, 2020): 737–42. http://dx.doi.org/10.47197/retos.v0i39.82548.
Full textAbstract:
Abstract. One of the main reasons for the decline in the level of the nation's health is the low manifestation of physical activity in school-age children. The study is relevant because it explores one of the effective ways to solve this issue – the introduction of physical folk games (PFG) in the educational system of the Republic of Kazakhstan. This will affect the physical development of schoolchildren and increase their involvement during physical education lessons. The purpose of this study was to investigate the effectiveness of physical activities in traditional Kazakh physical games. For this, the types of Kazakh PFGs were studied, their classification was developed, a survey was conducted among schoolchildren to find out their interest in folk games. After that, an educational experiment was set up, during which the positive influence of PFG on the development of the physical skills of children at physical education lessons became evident. It was discovered that the indicators of physical mobility of schoolchildren significantly improved: the number of students with a low level of physical mobility (PM) decreased from 50% to 13%, and the average level of PM in schoolchildren increased from 31% to 62%. Due to the developments of this study, it is possible to continue work on the implementation of PFGs in the educational process, since this process is accessible. Physical folk games do not require complex equipment, expensive buildings, and special conditions. It is also important to study the impact of Kazakh PFGs not only on children with normal development but also on children with special educational needs.
Resumen. Una de las principales razones del deterioro del nivel de salud de la nación es la baja manifestación de actividad física por parte de los niños en edad escolar. El artículo es relevante porque explora una de las formas efectivas de resolver este problema - la introducción de juegos folclóricos al aire libre en el sistema educativo de la República de Kazajstán. Esto afectará el desarrollo físico de los escolares y aumentará su participación durante las lecciones de educación física. El propósito de este estudio fue estudiar la efectividad de los juegos tradicionales kazajos al aire libre. Para esto se estudiaron los tipos de juegos populares kazajos al aire libre, se desarrolló su clasificación, se realizó una encuesta entre escolares para conocer su interés en los juegos folclóricos. Después de eso, se organizó un experimento pedagógico, durante el cual se hizo evidente la influencia positiva de juegos folclóricos al aire libre en el desarrollo de las habilidades físicas de los niños durante las lecciones de educación física. Se reveló que los indicadores de movilidad física de los escolares mejoraron significativamente: el número de estudiantes con un bajo nivel de movilidad física (MF) disminuyó del 50% al 13%, y el nivel promedio de MF de los escolares aumentó del 31% al 62%. Gracias al desarrollo de este estudio, es posible continuar trabajando en la implementación de juegos folclóricos al aire libre en el proceso educativo, ya que este proceso es accesible: los juegos folclóricos al aire libre no requieren equipos complejos, edificios costosos y condiciones especiales. También es importante estudiar la influencia de juegos folclóricos kazajas al aire libre no solo en los niños con normas de desarrollo, sino también en los niños con necesidades educativas especiales.
45
Das, Sankar, Ganesh Ghorai, and Qin Xin. "Picture Fuzzy Threshold Graphs with Application in Medicine Replenishment." Entropy 24, no. 5 (May 7, 2022): 658. http://dx.doi.org/10.3390/e24050658.
Full textAbstract:
In this study, a novel concept of picture fuzzy threshold graph (PFTG) is introduced. It has been shown that PFTGs are free from alternating 4-cycle and it can be constructed by repeatedly adding a dominating or an isolated node. Several properties about PFTGs are discussed and obtained the results that every picture fuzzy graph (PFG) is equivalent to a PFTG under certain conditions. Also, the underlying crisp graph (UCG) of PFTG is a split graph (SG), and conversely, a given SG can be applied to constitute a PFTG. A PFTG can be decomposed in a unique way and it generates three distinct fuzzy threshold graphs (FTGs). Furthermore, two important parameters i.e., picture fuzzy (PF) threshold dimension (TD) and PF partition number (PN) of PFGs are defined. Several properties on TD and PN have also been discussed. Lastly, an application of these developed results are presented in controlling medicine resources.
46
Shoaib, Muhammad, Waqas Mahmood, Qin Xin, and Fairouz Tchier. "Certain Operations on Picture Fuzzy Graph with Application." Symmetry 13, no. 12 (December 12, 2021): 2400. http://dx.doi.org/10.3390/sym13122400.
Full textAbstract:
Fuzzy graphs (FGs) can play a useful role in natural and human-made structures, including process dynamics in physical, biological, and social systems. Since issues in everyday life are often uncertain due to inconsistent and ambiguous information, it is extremely difficult for an expert to model those difficulties using an FG. Indeterminate and inconsistent information related to real-valued problems can be studied through a picture of the fuzzy graph (PFG), while the FG does not provide mathematically acceptable information. In this regard, we are interested in reducing the limitations of FGs by introducing some new definitions and results for the PFG. This paper aims to describe and explore a few properties of PFGs, including the maximal product (MP), symmetric difference (SD), rejection (RJ), and residue product (RP). Furthermore, we also discuss the degree and total degree of nodes in a PFG. This study also demonstrates the application of a PFG in digital marketing and social networking.
47
Ancy, Alex, and U. Parvathy. "Thermal Buckling Behaviour of Functionally Graded Plates." Applied Mechanics and Materials 857 (November 2016): 279–84. http://dx.doi.org/10.4028/www.scientific.net/amm.857.279.
Full textAbstract:
Functionally Graded Materials (FGM) are those materials which have continuous variation of material properties from metal phase to ceramic phase. Due to the continuous change in material properties of FGMs, the stress singularity at the interface between the two different materials is eliminated and thus the bonding strength is enhanced. They are widely used in high temperature environment such as nuclear reactors and rocket heat shields. The material property of FGM plate varies along the thickness direction and the variation is idealised by different mathematical idealisation techniques. This paper deals with the buckling behaviour of clamped PFGM plate under uniform temperature field. Thermal buckling behaviour of FGM plate has been obtained numerically through ANSYS software. The convergence study of the results is optimized by changing the mesh size. The critical buckling temperature rise obtained for functionally graded plates using ANSYS software are compared with the available literature. The effect of different parameters such as power-law index, thickness ratio, and aspect ratio on critical buckling temperature rise for temperature independent and dependent material properties of each constituent is also discussed. It is found that the critical buckling temperature rise decreases with the increase in power-law indices and thickness ratio and increases with increase in aspect ratio.
48
Griffen, Ti'ara L., Fieke W. Hoff, Yihua Qiu, James W. Lillard, Alessandra Ferrajoli, Philip A. Thompson, Endurance Toro, et al. "Proteomic Profiling Based Classification of CLL Provides Prognostication for Modern Therapy and Identifies Novel Therapeutic Targets." Blood 138, Supplement 1 (November 5, 2021): 1538. http://dx.doi.org/10.1182/blood-2021-151513.
Full textAbstract:
Abstract The availability of targeted therapy and improved molecular characterization of Chronic Lymphocytic Leukemia (CLL) require a re-evaluation of treatment paradigms. As CLL heterogeneity is dependent on molecular and environmental factors, there is a need to create a new classification based on the integration of several factors. Here, we accomplish this goal by identifying CLL signatures using Reverse Phase Protein Array. Protein expression for 384 total and post translationally modified proteins was assessed in 871 CLL and Mature Small B Cell Leukemia (MSBL: HCL, HCLV, LGL-T, MCL, MZL, PLL, Richter's, T-Cell PLL) patients and was integrated with clinical data to identify strategies for improving diagnostics and therapy, making this the largest CLL proteomics study to date. Proteins were categorized into 40 protein functional groups (PFGs) based on literature and intra-dataset protein correlations and patients clustered based on PFG expression patterns into 6 recurrent protein expression signatures (PES) (Figure 1A). Individual protein expression (58/384 proteins), PFG expression (32/40) and overall PES were all highly prognostic of survival (OS) and time to first or second treatment (TTFT, TTST) (Figures 1B-C). The adhesion, apoptosis-occurring, apoptosis-regulating, heat shock, histone1 (marks), histone 2 (modifiers) and the STP-regulation PFGs were prognostic for all 3 outcome measures. Notably SG-A contained most of the MSBL and 15/16 cases of hairy cell leukemia, but the CLL cases within this SG fared very poorly. For OS, groups A and C had markedly inferior survival (P<0.0001) (10.3 and 20.3 median years) relative to the other 4 groups, which were statistically similar to each other. First treatment occurred sooner for Groups A and C (5.8 and 5.23 median years). Additionally, the TTST was also inferior for Group A (median 3.5 years). There were significant differences in age, hemoglobin, platelets, % BM and PB lymphocytes and β2M between the SG, but not for race (p = 0.84) or gender (p = 0.72). , Historically adverse cytogenetic aberrations del 11q and del17p events (23% overall) were less common in SG A, B, D and E (15, 14, 16, 17%) and overrepresented in SG C (32%), while historically favorable 13q changes were seen across all groups as was Trisomy 12 (14% overall), although SGs A and E were enriched (25%, 22%) while SG-F was low (5%) for Trisomy 12. SG membership superseded other traditional prognostic factors (Rai Staging, IGHV Status) and were prognostic for modern (BTK inhibition) and older CLL therapies. SGs A and C responded poorly to chemotherapy regimens compared to the other groups, whereas all groups responded well to BTK inhibitors except for SG-A. SGs and PFGs membership provided novel drug targets (see our other abstracts on TP53BP1 and ASNS) and defined optimal candidates for Watch and Wait (WaW) vs. early intervention. A model based on the accumulation of irregularities in ANXA1, TFRC, and SMAD2.p245 expression, optimally predicted TTFT overall and in early stage CLL patients. Patients with < 1 negative level of either of the 3 proteins, have a median TTFT of 14.59 years, whereas patients having 2-3 have a median of 5-6.27 years (P<0.0001). CHEK1.pS345, GAB2, IGFBP2, S100A4, WEE1.pS642, and ZAP70 were universally overexpressed by all SGs, suggesting them as ideal targets for inhibition. Collectively proteomics demonstrates promise for improving classification, therapy strategy determination, and identifying novel therapeutic targets. Figure 1 Figure 1. Disclosures Ferrajoli: Janssen: Other: Advisory Board ; AstraZeneca: Other: Advisory Board, Research Funding; BeiGene: Other: Advisory Board, Research Funding. Thompson: Genentech: Other: Institution: Advisory/Consultancy, Honoraria, Research Grant/Funding; Amgen: Other: Institution: Honoraria, Research Grant/Funding; Adaptive Biotechnologies: Other: Institution: Advisory/Consultancy, Honoraria, Research Grant/Funding, Expert Testimony; Pharmacyclics: Other: Institution: Advisory/Consultancy, Honoraria, Research Grant/Funding; Janssen: Consultancy, Honoraria; Gilead: Other: Institution: Advisory/Consultancy, Honoraria; AbbVie: Other: Institution: Advisory/Consultancy, Honoraria, Research Grant/Funding. Burger: Pharmacyclics LLC: Consultancy, Other: Travel/Accommodations/Expenses, Research Funding, Speakers Bureau; Beigene: Research Funding, Speakers Bureau; TG Therapeutics: Other: Travel/Accommodations/Expenses, Research Funding, Speakers Bureau; Gilead: Consultancy, Other: Travel/Accommodations/Expenses, Research Funding, Speakers Bureau; Novartis: Other: Travel/Accommodations/Expenses, Speakers Bureau; AstraZeneca: Consultancy; Janssen: Consultancy, Other: Travel/Accommodations/Expenses, Speakers Bureau. Wierda: Xencor: Research Funding; Karyopharm: Research Funding; Gilead Sciences: Research Funding; Acerta Pharma Inc.: Research Funding; Pharmacyclics LLC, an AbbVie Company: Research Funding; AstraZeneca: Research Funding; Juno Therapeutics: Research Funding; KITE Pharma: Research Funding; Sunesis: Research Funding; Miragen: Research Funding; Oncternal Therapeutics, Inc.: Research Funding; Cyclacel: Research Funding; Loxo Oncology, Inc.: Research Funding; Janssen: Research Funding; Genentech: Research Funding; GSK/Novartis: Research Funding; Genzyme Corporation: Consultancy; AbbVie: Research Funding.
49
Zhang, Xiaolin, Muqier Hasi, Ang Li, Yulian Tan, Stefani Daryanto, Lixin Wang, Xueyao Zhang, Shiping Chen, and Jianhui Huang. "Nitrogen addition amplified water effects on species composition shift and productivity increase." Journal of Plant Ecology 14, no. 5 (March 31, 2021): 816–28. http://dx.doi.org/10.1093/jpe/rtab034.
Full textAbstract:
Abstract Aims Water and nitrogen (N) are two key resources in dryland ecosystems, but they may have complex interactive effects on the community structure and ecosystem functions. How future precipitation (rainfall vs snowfall) change will impact aboveground net primary production (ANPP) is far from clear, especially when combined with increasing N availability. Methods In this study, we investigated changes in community productivity, abundance and aboveground biomass of two dominant plant functional groups (PFGs), i.e. perennial rhizome grasses (PR) and perennial bunchgrasses (PB) under the impacts of increased precipitation (rainfall vs snowfall) combined with N addition in a semiarid temperate steppe. Important Findings Summer rainfall augmentation marginally increased community ANPP, whereas it significantly increased the abundance and aboveground biomass of PR, but not those of PB. Summer rainfall addition increased the fraction of PR biomass (fPR) while decreased that of PB (fPB). Spring snow addition had no effect on aboveground biomass of either compositional PFG although it marginally increased community ANPP. Nitrogen addition significantly increased community ANPP with greater increase in PR under summer rainfall addition, indicating strong interactive effects on community ANPP largely by enhancing PR biomass. We also found a nonlinear increase in the positive effect of nitrogen addition on productivity with the increased precipitation amount. These findings indicate an amplified impact of precipitation increase on grassland productivity under the accelerated atmospheric N deposition in the future.
50
Mancini, Silvia, Luigi Langellotto, Paolo Emilio Di Nunzio, Chiara Zitelli, and Andrea Di Schino. "Defect Reduction and Quality Optimization by Modeling Plastic Deformation and Metallurgical Evolution in Ferritic Stainless Steels." Metals 10, no. 2 (January 27, 2020): 186. http://dx.doi.org/10.3390/met10020186.
Full textAbstract:
Manufacturing of ferritic stainless steels flat bars is an important industrial topic and the steel 1.4512 is one of the most commonly used grades for producing this component. In this paper, the origin of some edge defects occurring during hot rolling of flat bars of this grade is analyzed and thermomechanical and microstructural calculations have been carried out to enhance the quality of the finished products by reducing the jagged borders defect on hot rolled bars. An accurate investigation has been carried out by analyzing the defects on the final product from both the macroscopic and microstructural point of view through the implementation of thermomechanical and metallurgical models in a finite element (FE) MSC Marc commercial code. Coupled metallurgical and damage models have been implemented to investigate the microstructural evolution of ferritic grain size and material damaging. Three levels of prior ferritic grain size (PFGS) and three furnace discharge temperatures have been considered in the thermo-mechanical simulations of the roughing passes. Rheological laws for modeling the evolution of ferritic grain have been modified to describe the specific cases simulated. Results have shown that the defect is caused by processing conditions that trigger an anomalous heating which, in turn, induces an uncontrolled grain growth on the edges. The work-hardened and elongated grains do not recrystallize during hot deformation. Consequently, they tend to squeeze out the surrounding softer and recrystallized matrix towards the edges of the bar where the fractures that characterizes the surface defect occur.