Academic literature on the topic 'PFAS toxicity'
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Journal articles on the topic "PFAS toxicity"
Seo, Sung-Hee. "Health risk of Human Exposure to Perfluorinated Compounds (PFASs) in Hyeongsan River, Pohang." Journal of Environmental Analysis, Health and Toxicology 25, no. 3 (September 30, 2022): 77–84. http://dx.doi.org/10.36278/jeaht.25.3.77.
Full textSeo, Sung-Hee. "Risk Assessment of Inhalation Exposure to Per-and Polyfluoroalkyl Substances (PFASs) in Industrial, Urban-residential and Rural Areas Near Hyeongsan River, Pohang." Journal of Environmental Analysis, Health and Toxicology 25, no. 2 (June 30, 2022): 51–57. http://dx.doi.org/10.36278/jeaht.25.2.51.
Full textRowan-Carroll, Andrea, Anthony Reardon, Karen Leingartner, Remi Gagné, Andrew Williams, Matthew J. Meier, Byron Kuo, et al. "High-Throughput Transcriptomic Analysis of Human Primary Hepatocyte Spheroids Exposed to Per- and Polyfluoroalkyl Substances as a Platform for Relative Potency Characterization." Toxicological Sciences 181, no. 2 (March 27, 2021): 199–214. http://dx.doi.org/10.1093/toxsci/kfab039.
Full textFey, Megan E., Philip E. Goodrum, N. Roxanna Razavi, Christopher M. Whipps, Sujan Fernando, and Janet K. Anderson. "Is Mixtures’ Additivity Supported by Empirical Data? A Case Study of Developmental Toxicity of PFOS and 6:2 FTS in Wildtype Zebrafish Embryos." Toxics 10, no. 8 (July 25, 2022): 418. http://dx.doi.org/10.3390/toxics10080418.
Full textMa, Tingting, Chaoran Ye, Tiantian Wang, Xiuhua Li, and Yongming Luo. "Toxicity of Per- and Polyfluoroalkyl Substances to Aquatic Invertebrates, Planktons, and Microorganisms." International Journal of Environmental Research and Public Health 19, no. 24 (December 13, 2022): 16729. http://dx.doi.org/10.3390/ijerph192416729.
Full textRenfrew, Daniel, and Thomas W. Pearson. "The Social Life of the “Forever Chemical”." Environment and Society 12, no. 1 (September 1, 2021): 146–63. http://dx.doi.org/10.3167/ares.2021.120109.
Full textGrandjean, P. "Epidemiological approaches to PFAS toxicity." Toxicology Letters 350 (September 2021): S53. http://dx.doi.org/10.1016/s0378-4274(21)00377-5.
Full textParolini, Marco, Beatrice De Felice, Marianna Rusconi, Michelangelo Morganti, Stefano Polesello, and Sara Valsecchi. "A review of the bioaccumulation and adverse effects of PFAS in free-living organisms from contaminated sites nearby fluorochemical production plants." Water Emerging Contaminants & Nanoplastics 1, no. 4 (2022): 18. http://dx.doi.org/10.20517/wecn.2022.15.
Full textUmar, Muhammad. "Reductive and Oxidative UV Degradation of PFAS—Status, Needs and Future Perspectives." Water 13, no. 22 (November 11, 2021): 3185. http://dx.doi.org/10.3390/w13223185.
Full textEmerce, Esra, and Özge Çetin. "Genotoxicity assessment of perfluoroalkyl substances on human sperm." Toxicology and Industrial Health 34, no. 12 (October 16, 2018): 884–90. http://dx.doi.org/10.1177/0748233718799191.
Full textDissertations / Theses on the topic "PFAS toxicity"
Shittu, Adenike Rofiyat. "Toxicity Studies Of Per- and Polyfluoroalkyl Substances (PFAS)." Bowling Green State University / OhioLINK, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=bgsu1625018658596765.
Full textO'Brien, Jason. "The Effects of Perfluoroalkyl Compounds on In Ovo Toxicity and Hepatic mRNA Expression in the Domestic Chicken (Gallus gallus domesticus)." Thèse, Université d'Ottawa / University of Ottawa, 2011. http://hdl.handle.net/10393/19924.
Full textJacquet, Nelly. "Étude "in vitro" du potentiel cancérogène d'organofluorés sur cellules embryonnaires de hamster Syrien (SHE)." Thesis, Université de Lorraine, 2012. http://www.theses.fr/2012LORR0394.
Full textPerfluorinated compounds (PFCs) is a collective name for fluorinated surfactants and polymers with the general structure CF3-(CF2)n-SO3- (sulfonates) or CF3-(CF2)n-1-CO2- .(acids). This group is characterized by a high persistence, bioaccumulation and long term toxicity which are rising environmental and public health concerns. In the present work, we analyzed the in vitro carcinogenic potential of the two major PFCs, perfluorooctane sulfonate (PFOS), and perfluorooctanoic acid (PFOA), and their substitute, perfluorobutane sulfonate (PFBS). Cell transformation assays were carried out on Syrian hamster embryo (SHE) cells in a 7 day-treatment using the standard and the initiation-promotion protocols. Genotoxicity was tested using the comet assay. PFOS was not genotoxic on SHE cells, but it induced cell transformation at non cytotoxic concentrations 0,37 and 3,7 µM (p<=0,01). These concentrations coincided with serum PFOS concentrations measured in occupationally exposed workers. An increased expression of PPARs was registered after 7 days. The ppar-beta/gamma mRNA appeared to increase rapidly (24 hours after PFOS treatment) at concentrations closely related to cell transformation (p<=0,05). PFOA was inactive alone, but induced cell transformation of SHE cells pre-initiated with benzo(a)pyrene (BaP). Therefore PFOA was shown to act as a tumor promoter and a non genotoxic carcinogen at a large range of concentrations (3,7 x 10-4 à 37 µM). This range of concentrations covered seric concentrations in non-occupationally exposed and occupationally exposed populations. PFBS was negative alone and on BaP-pretreated SHE cells. For this reason, its use as a substitute for PFOS appears to be justified. To conclude, the cell transforming potenty of PFOS and PFOA denotes in vitro carcinogenic potential. Consequently, the hypothesis of their implication in human cancer recorded in occupationally exposed populations cannot be ruled out
(10802253), Edgar Ramiro Perez. "AN ENVIRONMENTALLY RELEVANT BINARY MIXTURE OF PERFLUOROOCTANESULFONIC ACID AND PERFLUOROHEXANESULFONIC ACID RESULTS IN ANTAGONISM AND REDUCED BODY CONDITION IN NORTHERN LEOPARD FROGS." Thesis, 2021.
Find full textPerfluoroalkyl substances are synthetic organic chemicals of environmental concern because they have been associated with adverse effects in both human epidemiological studies and standard laboratory animals. In the environment, PFAS occur as mixtures, especially in areas with a history of PFAS application, such as aqueous film forming foam (AFFF) sites. Among the PFAS, perfluorooctanesulfonic acid (PFOS) and perfluorohexanesulfonic acid (PFHxS) are the most common, and occur at the highest concentrations. Thus, amphibian populations at or near AFFF sites are at risk of exposure to known bioaccumulative and persistent chemicals, likely compromising the physiology and body condition of the animals. Here, we exposed northern leopard frogs to environmentally relevant concentrations of 0.5 and 1 ppb PFOS and PFHxS, alone or as a mixture comprised of 0.5 ppb PFOS and 0.5 ppb PFHxS. Univariate analyses showed that in the larval stages, tadpoles exposed to PFAS had significantly reduced scaled mass indexes (SMI’s) relative to the control, and only the organisms exposed to PFHxS 0.5 ppb were significantly larger. Sex did not significantly influence toxicity in the later stages (GS 42 & 46), indicating no sex-related effects. Altered body condition (i.e., fat stores) in the larval stages indicate potential effects to energy balance. There is a need to assess fitness-related effects as amphibians’ transition into the terrestrial environment, and include endpoints such as: reproductive, developmental, immunological, mating, feeding, competition, and survival. Early developmental effects in the larval stages also suggests that earlier developmental endpoints may be of interest. Establishing ecological risk assessments for PFAS are necessary, as they are toxic, persistent, and bioaccumulative.
Book chapters on the topic "PFAS toxicity"
Morschhauser, Franck, and Pier Luigi Zinzani. "Indolent Lymphomas." In The EBMT/EHA CAR-T Cell Handbook, 83–86. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-94353-0_15.
Full textÖzmert, Elif N. "Erken Çocuklukta Gelişimsel Sorunlar ve Endokrin Bozucular." In Endokrin Bozucular ve Sağlık, 99–116. Türkiye Bilimler Akademisi Yayınları, 2022. http://dx.doi.org/10.53478/tuba.978-625-8352-04-7.ch06.
Full textKanellias, Nikolaos, Maria Gavriatopoulou, and Evangelos Terpos. "Antibody Therapies for Multiple Myeloma." In Multiple Myeloma [Working Title]. IntechOpen, 2021. http://dx.doi.org/10.5772/intechopen.98656.
Full textConference papers on the topic "PFAS toxicity"
Vatsa, Richa, Sunesh Kumar, and Lalit Kumar. "To assess the role of addition of bevacizumab therapy to carboplatin and paclitaxel as frontline treatment of epithelial ovarian cancer." In 16th Annual International Conference RGCON. Thieme Medical and Scientific Publishers Private Ltd., 2016. http://dx.doi.org/10.1055/s-0039-1685308.
Full textLee, Jai-yeop, Hyun-dong Lee, and Il-ho Ki. "Bio-toxicity Assessment of PFOA and PFOS to Vibrio fischeri by Photomultiplier Tube." In Information Technology and Computer Science 2015. Science & Engineering Research Support soCiety, 2015. http://dx.doi.org/10.14257/astl.2015.99.17.
Full textEvans, William, Jazmine Eccles, and William Baldwin. "Changes in Energy Metabolism Induced by PFOS and Dietary Oxylipins." In 2022 AOCS Annual Meeting & Expo. American Oil Chemists' Society (AOCS), 2022. http://dx.doi.org/10.21748/jnpe5541.
Full textClifton, KK, J. Kimmel, M. Yi, B. Chad, J. Litton, T. Debu, and K. Meghan. "Abstract P3-11-03: The impact of dose delays and reductions on toxicity and progression free survival (PFS) in patients receiving palbociclib." In Abstracts: 2017 San Antonio Breast Cancer Symposium; December 5-9, 2017; San Antonio, Texas. American Association for Cancer Research, 2018. http://dx.doi.org/10.1158/1538-7445.sabcs17-p3-11-03.
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