Journal articles on the topic 'Persistent allergic rhinitis'
To see the other types of publications on this topic, follow the link: Persistent allergic rhinitis.
Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles
Consult the top 50 journal articles for your research on the topic 'Persistent allergic rhinitis.'
Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.
You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.
Browse journal articles on a wide variety of disciplines and organise your bibliography correctly.
1
Klimov, A. V., P. Yu Isaev, V. V. Klimov, and V. S. Sviridova. "Endotypes of allergic rhinitis and asthma accompanying food allergy." Bulletin of Siberian Medicine 18, no. 2 (August 11, 2019): 287–89. http://dx.doi.org/10.20538/1682-0363-2019-2-287-289.
Full textAbstract:
61 people suffering from persistent allergic rhinitis and asthma accompanying food allergies were studied using case histories, the NHANES questionnaire, polyspecific serum levels, allergen-specific IgE, IL4, IFNg and IL10 assays, and allergy skin tests. Four different endotypes have been identified, including entopic, which can be the basis for new approaches to the diagnosis and treatment of allergic rhinitis and asthma.
2
Aleksic, Aleksandra, Mirjana Gnjatic, Mirjana Stupar-Hofman, and Vesna Tomic-Spiric. "Allergic rhinitis, part of the allergic respiratory syndrome." Medical review 73, no. 9-10 (2020): 301–8. http://dx.doi.org/10.2298/mpns2010301a.
Full textAbstract:
Introduction. Diseases associated with immunoglobulin E hypersensitivity, such as allergic rhinitis, may have different clinical expressions. Patients with allergic rhinitis often have associated diseases, comorbidities, which supports the concept of allergy as a systemic disease. The aim of this study was to evaluate the incidence and types of comorbidities in allergic rhinitis. We also evaluated the possible effects of certain clinical and demographic parameters on the onset of comorbidities. Material and Methods. This retrospective, observational, and cross-sectional study included patients with a clinical diagnosis of allergic rhinitis treated at the Department of Ear, Nose and Throat in the period from October 2011 to April 2013. The collected data were analyzed using the Statistical Analysis System (Institute Inc. NC, USA) program, version 9.1.3. Results. The study included 319 patients with allergic rhinitis. Allergic rhinitis was intermittent in 30.7% of cases, persistent in 37.9%, and persistent with seasonal exacerbation in 31.3% of patients. We found that 86.8% of patients had some form of comorbidity. The most common were conjunctivitis (50.2%), almost equal percentage of asthma (29.8%) and chronic rhinosinusitis (28.8%), followed by otitis media with effusion (8.8%), atopic dermatitis (5.2%), urticaria (4.1%), and laryngitis (3.8%). Persistent allergic rhinitis, with persistent nasal obstruction as the dominant symptom, was significantly associated with chronic rhinosinusitis. Positive family history was significantly associated with the occurrence of asthma and allergic rhinitis. Conclusion. The results of our study showed that allergic rhinitis is rarely an isolated condition and it should always be observed in the context of the allergic respiratory syndrome.
3
Poza Guedes, Paloma, Inmaculada Sánchez Machín, Víctor Matheu, Víctor Iraola, and Ruperto González Pérez. "Role of Predatory Mites in Persistent Nonoccupational Allergic Rhinitis." Canadian Respiratory Journal 2016 (2016): 1–5. http://dx.doi.org/10.1155/2016/5782317.
Full textAbstract:
Mites can sensitize and induce atopic disease in predisposed individuals and are an important deteriorating factor in patients with allergic rhinitis, asthma, and atopic dermatitis. Although Pyroglyphidae mites have been extensively studied, very scarce reports are available on Cheyletidae spp. especially regarding human respiratory pathology. The main objective of the present study is to investigate the clinical role of this predator mite (Cheyletus eruditus) as a respiratory antigen in a selected sensitized human population. Fifty-two adult patients were recruited from the outpatient allergy clinic to assess their eligibility for the study. The thirty-seven subjects with persistent allergic rhinitis (PAR) who fulfilled the ARIA criteria had a positive IgE response confirmed by skin prick test (SPT) toC. eruditus. Only those individuals (37/47) with a positive SPT toC. eruditusshowed a positive nasal provocation test (NPT), while 10 patients with nonallergic mild-to-moderate persistent rhinitis,control group, had a negative NPT withC. eruditus. The present paper describes a new role for the predator miteCheyletus eruditusas a respiratory allergen in a selected subset of patients in a subtropical environment afflicted with persistent nonoccupational allergic rhinitis.
4
Berkiten, G., İ. Aydoğdu, T. L. Kumral, Z. Saltürk, Y. Uyar, A. Arslanoğlu, B. Tutar, and A. E. Göker. "Nasal eosinophilia in nasal smears of patients with persistent and intermittent allergic rhinitis." Journal of Laryngology & Otology 132, no. 11 (November 2018): 1018–21. http://dx.doi.org/10.1017/s0022215118001986.
Full textAbstract:
AbstractBackgroundEosinophils are the principal effector cells involved in the pathogenesis of allergic rhinitis. Cell numbers increase in non-allergic rhinitis patients with eosinophilia, aspirin hypersensitivity and nasal polyposis, as well as in allergic rhinitis patients. Exfoliative nasal cytology can be used in the differential diagnosis of allergic rhinitis.ObjectiveTo evaluate nasal eosinophilia in nasal smears of patients with mild, persistent and intermittent allergic rhinitis.MethodsThe study comprised 60 patients with allergic rhinitis and 20 healthy volunteers. The patients were divided into intermittent and persistent allergic rhinitis groups. Nasal smear status, eosinophil numbers and Total Nasal Symptom Scores were compared.ResultsNasal smear results were pathological in 40 of 60 allergic rhinitis patients, which was significantly higher than the rate in controls. The mean nasal eosinophilia score was significantly higher in the intermittent allergic rhinitis than in the persistent allergic rhinitis group (p= 0.029). There was a positive correlation between nasal eosinophilia score and Total Nasal Symptom Score (r = 0.652;p< 0.05) in persistent allergic rhinitis and intermittent allergic rhinitis patients.ConclusionThe nasal smear test is inexpensive, objective and simple to perform, and should be part of the diagnostic investigation.
5
Tyurin, Yu A., E. I. Shapkina, I. G. Mustafin, and R. S. Fassakhov. "The features of mucosal immunity and microbiota at different forms of allergic rhinitis." Kazan medical journal 94, no. 5 (October 15, 2013): 766–70. http://dx.doi.org/10.17816/kmj1940.
Full textAbstract:
Aim. To assess the parameters of local immune response in patients with different forms of allergic rhinitis, associated with nasal bacterial infection. Methods. Nasal swabs and nasal epithelium samples obtained from 10 patients with seasonal allergic rhinitis aged 12 to 32 years and from 15 patients with persistent allergic rhinitis aged 18 to 45 years, as well as form the 20 healthy subjects aged 18 to 45 years without signs of allergy who were age and gender-comparable, were examined. Swabs were prepared from cell suspension, stained with 0.04% trypan blue solution, and a microscopy with the count of non-stained cells was performed. Epitheliocytes expressing toll-like receptors-2, were determined by flow cytometry. Interleukin-10 concentration in swabs was assessed by ELISA. Results. The number of epitheliocytes expressing toll-like receptors-2 was by 1.9 times lower in patients with seasonal allergic rhinitis and by 1.7 times lower in patients with persistent allergic rhinitis compared to control group. There was a reverse correlation found between the number of epitheliocytes expressing toll-like receptors-2 and interleukin-10 level in nasal swabs of healthy controls, while in patients with allergic rhinitis a it was a direct correlation. In patients with persistent allergic rhinitis S. aureus was a part of microbiota in 100% of cases and was associated with other bacteria (Str. pyogenes - 33.3%, Neisseria spp. - 66.7%). In patients with seasonal allergic rhinitis the association of S. aureus and S. hemolyticus (70.0%) was the most frequent one. In the control group, S. epidermidis (50.0%), Str. viridians (25.0%), S. hominis (25.0%) were among the nasal microbiota. There were no differences revealed between the mean levels of interleukin-10 in patients with allergic rhinitis and healthy controls. Conclusion. The number of epitheliocytes expressing toll-like receptors-2 was significantly reduced by almost 2 times in patients with persistent allergic rhinitis compared to control group. Colonization of nasal mucosa by S. aureus in patients with allergic rhinitis leads to an increase of epithelial cells expressing toll-like receptors-2.
6
Song, Y., J. Long, T. Wang, J. Xie, M. Wang, and G. Tan. "Long-term efficacy of standardised specific subcutaneous immunotherapy in children with persistent allergic rhinitis due to multiple allergens including house dust mites." Journal of Laryngology & Otology 132, no. 3 (January 28, 2018): 230–35. http://dx.doi.org/10.1017/s0022215117002547.
Full textAbstract:
AbstractObjectives:To observe the five-year efficacy of standardised specific subcutaneous immunotherapy for house dust mite allergy in monosensitised and polysensitised children with persistent allergic rhinitis.Methods:From January 2007 to August 2009, 236 children with persistent allergic rhinitis were divided into 2 groups: 1 group received standardised specific subcutaneous immunotherapy using house dust mite extract; the other received pharmacotherapy with intranasal corticosteroids and oral antihistamines. A total of 193 patients (106 in the immunotherapy group and 87 in the pharmacotherapy group) completed treatment. Scores for symptoms, total medication and quality of life were evaluated.Results:The subcutaneous immunotherapy group demonstrated a significant reduction in visual analogue scale scores, Rhinoconjunctivitis Quality of Life Questionnaire scores and total medication scores (p < 0.05) compared with the pharmacotherapy group. No significant differences in the visual analogue scale and Rhinoconjunctivitis Quality of Life Questionnaire scores were found between the polysensitised and monosensitised subgroups (p > 0.05). No serious adverse events occurred.Conclusion:Standardised subcutaneous immunotherapy has long-term efficacy for children with persistent allergic rhinitis. Single-allergen subcutaneous immunotherapy was appropriate for allergic rhinitis caused by multiple allergens, including house dust mites, in the paediatric population.
7
Shakhova, N. V., V. V. Gordeev, U. F. Lobanov, T. S. Ardatova, and M. V. Surcova. "Clinical and allergological characteristic of children with allergic rhinitis receiving allergen-specific immunotherapy in Altai region." Russian Journal of Allergy 12, no. 2 (December 15, 2015): 64–67. http://dx.doi.org/10.36691/rja468.
Full textAbstract:
The purpose of this study. To investigate clinical characteristics of the allergic rhinitis in children receiving allergen-specific immunotherapy. Methods. The epidemiologic observational multicenter study was conducted with the allergists of Altai region. The participating allergists filled out the specially designed medical record card on children with allergic rhinitis receiving ASIT. The study lasted from October 2013 to March 2014. Results. Allergists have filled out medical record cards of 165 children with allergic rhinitis receiving ASIT. The average age of children was 10,5±2,3 years, with the average of 4,8±2,5 years of allergic rhinitis prior to the start of ASIT. 159 (96,2%) children had moderate/severe allergic rhinitis, and 121 (73,3%) children had persistent allergic rhinitis. In 123 (74,5%) children rhinitis was accompanied by allergic conjunctivitis, and in 70 (42,2%) children - by bronchial asthma. 69 (41,8%) children receiving ASIT were mono-sensitized, 96 (58,2%) children were polysensitized. 48,5% of children were sensitized to house dust mites, 63,6% to tree pollen, 48,5% to meadow grass pollen, 30,9% to weed pollen, and in 21,8% sensitization to epidermal allergens was found. Conclusion. The findings of the study showed that in most cases (96,2%), children with allergic rhinitis receiving ASIT had moderate/severe rhinitis and in 73,3% symptoms were persistent. In 74,5% of cases, allergic rhinitis was accompanied by allergic conjunctivitis. Most part of children receiving ASIT had multiple sensitization (58,2%). Also a delayed beginning of ASIT was observed - 4,8±2,5 year from primary diagnosis to ASIT initiation.
8
Bachert, C. "Persistent rhinitis - allergic or nonallergic?" Allergy 59, s76 (January 2004): 11–15. http://dx.doi.org/10.1111/j.0108-1675.2004.00389.x.
Full text
9
Bella, Zsolt, Ágnes Kiricsi, Éva Dósa-Rácz Viharosné, Attila Dallos, Ádám Perényi, Mária Kiss, Andrea Koreck, et al. "Rhinophototherapy in persistent allergic rhinitis." European Archives of Oto-Rhino-Laryngology 274, no. 3 (November 18, 2016): 1543–50. http://dx.doi.org/10.1007/s00405-016-4358-x.
Full text
10
Антонюк, Марина, Marina Antonyuk, С. Сулейманов, S. Suleymanov, Татьяна Гвозденко, Tatyana Gvozdenko, Татьяна Новгородцева, and Tatyana Novgorodtseva. "EFFICIANCY OF IMMUNOTHERAPY IN PATIENTS WITH PERSISTENT ALLERGIC RHINITIS." Bulletin physiology and pathology of respiration 1, no. 70 (December 29, 2018): 32–37. http://dx.doi.org/10.12737/article_5c1264ee93f132.73406573.
Full textAbstract:
The dynamics of parameters of cytokine status in patients with allergic rhinitis in view of efficiency of allergen-specific immunotherapy (ASIT) was studied in this work. 62 subjects with moderate persistent rhinitis at the age of 18-40 years old were included in the study. For specific diagnosis and treatment there we used standard allergens. ASIT was performed by the classical scheme. The concentrations of IL-4, IL-5, IL-6, IL-8 in the blood serum were measured by the enzyme immunoassay. A good or excellent effect of treatment with ASIT was achieved in 62.9% of cases, and satisfactory one in 37.1% of cases. The analysis of the dynamics of IL-4, IL-5, IL-6, IL-8 concentrations showed that the efficiency of ASIT in patients with allergic rhinitis depends on the ability of the immune system to activation by low doses of the allergen, quite fast suppression of proinflammatory cytokines induced by them, and active functioning of the system of anti-inflammatory cytokines.
11
Guseva, A. L., and M. L. Derbeneva. "Rhinitis: differential diagnosis and treatment principles." Meditsinskiy sovet = Medical Council, no. 16 (November 14, 2020): 102–8. http://dx.doi.org/10.21518/2079-701x-2020-16-102-108.
Full textAbstract:
Rhinitis is inflammation of the mucous membrane inside the nose. The clinical symptoms of this disease include nasal congestion, sneezing, itching of the nose and roof of mouth, rhinorrhea, and mucus draining down the back of the throat. Both allergic and non-allergic factors can play a role in the development of rhinitis. The most commonly used classification of rhinitis includes allergic rhinitis, non-allergic rhinitis, infectious rhinitis, and its specific forms. Allergic rhinitis is classified into the intermittent or persistent types, and may also be classified as mild, moderate and severe according to the severity of symptoms. Treatment of allergic rhinitis includes elimination of contact with allergen, allergen-specific immunotherapy and pharmacotherapy, which is selected depending on the severity of the symptoms. Infectious rhinitis develops in acute viral infection, and rhinitis symptoms are present in acute and chronic rhinosinusitis. Non-allergic rhinitis comprises conditions ranging from vasomotor rhinitis and gustatory rhinitis to non-allergic rhinitis with eosinophilia syndrome. Mixed rhinitis has components of allergic and non-allergic rhinitis. In addition, there are CPAP rhinitis, occupational rhinitis, medication rhinitis, rhinitis in systemic administration of drugs, rhinitis of pregnant women, atrophic rhinitis, rhinitis in systemic diseases. The type of rhinitis is diagnosed based on the patient’s complaints, anamnesis and clinical picture, some cases require laboratory tests and CT scan of the paranasal sinuses to differentiate the diagnosis. Approaches to the treatment of rhinitis depend on its type and include elimination of allergens or provoking factors, administration of saline solutions, intranasal glucocorticosteroids, systemic antihistamines, intranasal cromones, decongestants, antibacterial drugs may be prescribed to treat infectious rhinitis. Rhinitis should be differentiated from structural abnormalities, including congenital features, acquired conditions, neoplasms, gastroesophageal reflux, nasal liquorrhea.
12
Omusheva, S. "Modern Diagnostics and Treatment of Allergic Rhinitis in Children in the Kyrgyz Republic." Bulletin of Science and Practice 6, no. 1 (January 15, 2020): 129–37. http://dx.doi.org/10.33619/2414-2948/50/14.
Full textAbstract:
The aim of the study was to study the detection and treatment of allergic rhinitis in children in the Kyrgyz Republic. A prospective study included 79 children with suspected allergic rhinitis. It was found that 79 patients were diagnosed with allergic rhinitis using an adapted questionnaire. Late reversibility, the duration of the disease on average 3 years from the onset of the first symptoms, and a severe course, indicate a diagnosis of the disease. In allergic rhinitis intermittent flow, sensitization to pollen of cereals and trees predominates, and in persistent, weed, domestic, and epidermal allergens are noted. The effectiveness of subcutaneous and sublingual allergen-specific immunotherapy methods in children was evaluated.
13
Baran, H., K. M. Ozcan, A. Selcuk, M. A. Cetin, S. Cayir, M. Ozcan, and H. Dere. "Allergic Rhinitis and its Impact on Asthma classification correlations." Journal of Laryngology & Otology 128, no. 5 (April 30, 2014): 431–37. http://dx.doi.org/10.1017/s0022215114000693.
Full textAbstract:
AbstractObjective:Allergic rhinitis is inflammation of the nasal mucosa following exposure to allergens. A few studies have investigated how the Allergic Rhinitis and its Impact on Asthma classification correlates with symptom severity and skin prick test results in allergic rhinitis patients. Our objective was to evaluate such a correlation.Materials and methods:The study population consisted of 268 patients who had allergic symptoms and were diagnosed with allergic rhinitis.Results:Analysis of the Allergic Rhinitis and its Impact on Asthma classification with regard to symptom severity revealed that there were statistically significant differences between the groups for nasal symptoms, wheezing, eye itching/watering and eye redness. Symptom frequency and severity increased gradually towards the moderate to severe persistent allergic group. There was a statistically significant difference between the groups for grass pollen and house dust mite allergy.Conclusion:The Allergic Rhinitis and its Impact on Asthma classification, which takes symptoms and quality of life into consideration in addition to allergen exposure, is a useful classification system for allergic rhinitis.
14
Agnihotri, Neha T., and Kris G. McGrath. "Allergic and nonallergic rhinitis." Allergy and Asthma Proceedings 40, no. 6 (November 1, 2019): 376–79. http://dx.doi.org/10.2500/aap.2019.40.4251.
Full textAbstract:
Rhinitis is characterized by nasal congestion, rhinorrhea, sneezing, and/or posterior nasal drainage. It affects a significant portion of the population and presents a large burden economically and on quality of life. Rhinitis is broadly characterized as allergic and nonallergic, of which nonallergic rhinitis may be divided into inflammatory and noninflammatory etiologies. The inflammatory causes include nonallergic rhinitis with eosinophilia, postinfectious, and rhinitis associated with nasal polyps. The noninflammatory causes include idiopathic nonallergic (vasomotor) rhinitis, medication-induced rhinitis, hormone related (e.g., pregnancy), and systemic disease related. Allergic rhinitis is classified as intermittent or persistent and mild versus moderate-severe. The nasal mucosa is extremely vascular; parasympathetic stimulation promotes an increase in nasal cavity resistance and nasal gland secretion, whereas sympathetic stimulation leads to vasoconstriction. The diagnosis of rhinitis begins with a directed history, particularly noting pattern, chronicity, and triggers of symptoms. Examination of the nasal cavity with attention to appearance of the septum and inferior turbinates is recommended. Skin testing for aeroallergens is helpful in demonstrating the presence or absence of immunoglobulin E antibodies and to differentiate nonallergic from allergic rhinitis. Treatment includes patient education, irritant or allergen avoidance, and pharmacotherapy. Medications used for the treatment of rhinitis include intranasal corticosteroids, oral and intranasal antihistamines, intranasal anticholinergic agents, oral decongestants, and leukotriene receptor antagonists. When used in combination, an intranasal antihistamine spray and nasal steroid provide greater symptomatic relief than monotherapy. Allergen immunotherapy is the only disease-modifying intervention available for allergic rhinitis.
15
Znamenskaya, L. K., N. A. Shadchneva, and G. N. Panevskaya. "EXPERIENCE IN THE USE OF ALLERGEN-SPECIFIC IMMUNOTHERAPY IN TREATMENT OF PERENNIAL ALLERGIC RHINITIS AND CONCOMITANT ATOPIC DERMATITIS." Pediatria. Journal named after G.N. Speransky 100, no. 2 (April 12, 2021): 261–66. http://dx.doi.org/10.24110/0031-403x-2021-100-2-261-266.
Full textAbstract:
Allergen-specific immunotherapy (ASIT) is currently recognized as the only treatment that can affect all links in the pathological process of allergic diseases. Airway hyperresponsiveness is significantly reduced in case of allergy respiratory manifestations, which reduces symptoms severity and the need for drugs. The article describes a clinical observation of the ASIT positive effect in persistent atopic dermatitis (AtD) with concomitant respiratory allergy and complete atopic triad development. The authors propose to consider ASIT as a preventive therapy for bronchial asthma and allergic rhinitis if patient has AtD manifestations with confirmed sensitization to aeroallergens.
16
Qu, Jing, Chang Liu, Hai-Hong Lian, Xiang-Dong Wang, and Nan Zhi. "Qingfeijianpi therapy for persistent allergic rhinitis." Medicine 97, no. 23 (June 2018): e10961. http://dx.doi.org/10.1097/md.0000000000010961.
Full text
17
Canonica, G., and Ilaria Baiardini. "Minimal Persistent Inflammation in Allergic Rhinitis." Allergy & Clinical Immunology International - Journal of the World Allergy Organization 18, no. 04 (2006): 169–71. http://dx.doi.org/10.1027/0838-1925.18.4.169.
Full text
18
Bozkurt, Bulent, K. Serife Ugur, Harun Karamanli, Fatma Kucuker, and Duygu Ozol. "Polysomnographic findings in persistent allergic rhinitis." Sleep and Breathing 21, no. 2 (August 1, 2016): 255–61. http://dx.doi.org/10.1007/s11325-016-1390-4.
Full text
19
Bozkurt, Bulent, Kadriye Serife Ugur, Fatma Kucuker, and Duygu Ozol. "Polysomnographic Findings in Persistent Allergic Rhinitis." Journal of Allergy and Clinical Immunology 135, no. 2 (February 2015): AB269. http://dx.doi.org/10.1016/j.jaci.2014.12.1819.
Full text
20
Virtanen, Suvi M., Minna Kaila, Juha Pekkanen, Michael G. Kenward, Ulla Uusitalo, Pirjo Pietinen, Carina Kronberg-Kippilä, et al. "Early introduction of oats associated with decreased risk of persistent asthma and early introduction of fish with decreased risk of allergic rhinitis." British Journal of Nutrition 103, no. 2 (August 13, 2009): 266–73. http://dx.doi.org/10.1017/s0007114509991541.
Full textAbstract:
The evidence of the effect of the age at introduction of new foods during infancy on the development of asthma and allergic rhinitis is inconsistent and scarce. We set out to study these associations. A prospective birth cohort of infants with increased HLA-DQB1-conferred risk for type 1 diabetes was recruited in 1996–2000. The families completed at home a record on the age at introduction of new foods. Persistent asthma and allergic rhinitis were assessed at the age of 5 years with an International Study of Asthma and Allergies in Childhood-type questionnaire. The Cox proportional hazards regression analyses were adjusted for parental asthma and allergic diseases, and several perinatal and sociodemographical factors. Out of the 1293 children, 77 (6·0 %) developed persistent asthma; and out of the 1288 children, 185 (14·4 %) developed allergic rhinitis by the age of 5 years. Early age at introduction of oats was associated with a reduced risk of persistent asthma (hazard ratio (HR; 95 % CI) for the first and mid-tertiles compared with the latest tertile was 0·36 (0·15, 0·85) and 0·37 (0·22, 0·62), respectively, P < 0·001). Early age at introduction of fish was dose dependently associated with a decreased risk of allergic rhinitis (HR (95 % CI) for the first and mid-tertiles compared with the latest tertile was 0·34 (0·22, 0·54) and 0·45 (0·28, 0·70), respectively, P < 0·001). The present finding that age at introduction of oats is inversely and independently associated with development of persistent asthma is novel. We confirmed the earlier observation that the age at introduction of fish is inversely related to the risk of allergic rhinitis. Clinical implications remain to be determined.
21
Lopez, S., C. Rondon, R. R-Pena, C. Mayorga, M. J. Torres, C. Antunez, J. J. Romero, J. A. Cornejo-Garcia, and M. Blanca. "Nasal Flow Cytometry in the Diagnosis of Persistent Allergic Rhinitis and Persistent Idiopathic Non-Allergic Rhinitis." Journal of Allergy and Clinical Immunology 117, no. 2 (February 2006): S164. http://dx.doi.org/10.1016/j.jaci.2005.12.656.
Full text
22
Nyembue, Tshipukane Dieudonné, Wivine Ntumba, L. August Omadjela, Christophe Muyunga, Peter W. Hellings, and Mark Jorissen. "Sensitization Rate and Clinical Profile of Congolese Patients with Rhinitis." Allergy & Rhinology 3, no. 1 (January 2012): ar.2012.3.0023. http://dx.doi.org/10.2500/ar.2012.3.0023.
Full textAbstract:
In the African continent, the sensitization pattern and clinical profile are unknown in patients with rhinitis/rhinosinusitis attending the outpatient ear, nose, and throat (ENT) clinics. We therefore aimed to analyze the clinical characteristics of rhinitis/rhinosinusitis patients in Democratic Republic of Congo (DRC), classify allergic rhinitis (AR) according to the Allergic Rhinitis and Its Impact on Asthma criteria, and evaluate the sensitization profile and its associated factors. From January to May 2009, 423 patients with rhinitis symptoms attending the Outpatient ENT clinic of the University Hospital and Saint Joseph Hospital of Kinshasa were evaluated for allergy symptoms, severity, and duration of symptoms and underwent skin-prick tests (SPTs) for a panel of 15 allergens. Of 423 patients 35.2% had positive SPT results, with 40.9% showing polysensitization. Dermatophagoides pteronyssinus (DPT) (68.5%) and cockroach (36.2%) were the most common allergens among sensitized patients. Patients with rhinitis/rhinosinusitis mainly presented in decreasing order with sneezing, facial pain/pressure, nasal obstruction, postnasal discharge, nose itching, clear nasal discharge, and eye itching. Persistent and moderate/severe AR represented 61.4 and 69.3%, respectively. Sensitization was independently associated with younger age, rhinoconjunctivitis, and reaction to nonspecific trigger factors. In conclusion, 35.2% of patients attending the ENT Outpatient Clinic in DRC for rhinitis problems had a positive SPT to at least one allergen, with mainly DPT and cockroach allergens being involved; and a substantial portion showed persistent and moderate/severe AR. Therefore, allergy should not be neglected as an etiologic factor in rhinologic disease in the African continent.
23
Sumadiono, Sumadiono, Cahya Dewi Satria, Nurul Mardhiah, and Grace Iva Susanti. "Immunotherapy and probiotic treatment for allergic rhinitis in children." Paediatrica Indonesiana 58, no. 6 (December 10, 2018): 280–5. http://dx.doi.org/10.14238/pi58.6.2018.280-5.
Full textAbstract:
Background Allergic rhinitis is a global health problem that is increasing in prevalence. Many kinds of therapy have been tried, such as antihistamines, probiotics, and immunotherapy. Immunotherapy may restore the patient’s normal immunity against the specific allergen, while probiotics may modify the natural course of allergy.
Objective To evaluate probiotics and immunotherapy for improving clinical symptoms of allergic rhinitis.
Methods This randomized controlled trial (RCT) involved 64 patients, aged 3-18 years, and diagnosed with persistent allergic rhinitis in the Department of Child Health, Sardjito General Hospital from April 2016 until May 2017. Patients were randomly allocated into three therapy groups: group A (standard therapy/cetirizine only), group B (standard and probiotic therapy), and group C (standard therapy and immunotherapy). Clinical symptoms of allergic rhinitis including sneezing, rhinorrhea, and itchy nose, were evaluated for 7 weeks and classified as improved or not improved. The significance of the data was analyzed using proportion test.
Results Sixty-four patients completed 7 weeks of therapy, 15 subjects in group A, 26 in group B, and 23 in group C. Group C showed significantly more improvement of sneezing and rhinorrhea compared to both group A (Z=5.71; Z=7.57, respectively) and group B (Z=2.82; Z=6.90, respectively). However, itchy nose was not significantly improved in group C compared to group B (Z=0.50), but was significantly improved in group C compared to group A (Z=10.91). Group B had significant improvement of sneezing, rhinorrhea, and itchy nose compared to group A (Z=3.81, Z=2.86, and Z=10.91, respectively).
Conclusion The combined standard-immunotherapy group has significantly superior improvement compared to the combined standard-probiotic group and the standard therapy group, in terms of sneezing and rhinorrhea in children with persistent allergic rhinitis.
24
Gandaputra, Ellen P., Zakiudin Munasir, Bambang Supriyatno, and Jose R. L. Batubara. "Effect of intranasal mometasone furoate administered in children with coexisting allergic rhinitis and asthma towards asthma attacks and lung function." Paediatrica Indonesiana 49, no. 6 (December 31, 2009): 359. http://dx.doi.org/10.14238/pi49.6.2009.359-64.
Full textAbstract:
Background Allergic rhinitis and asthma are allergic manifestations in respiratory tract, which related each other. Intranasal corticosteroid is effective in allergic rhinitis and has benefits in decreasing lower airway reactivity.Objectives To evaluate effectiveness of intranasal mometasonefuroate towards asthma in children aged 6-18 years with coexisting allergic rhinitis and asthma.Methods A one group pretest-posttest ("before and after") study was conducted in Cipto Mangunkusumo Hospital from May to December 2008. Subjects were children aged 6-18 years, with moderate-severe intermittent or persistent allergic rhinitis with coexisting frequent episodic asthma or persistent asthma, and visited outpatient clinic of allergy immunology division or respirology division. Subjects were administered intranasal mometasone furoate 100 J-ig daily only for 8 weeks, without long term administration of oral and inhaled corticosteroid. Improvements in allergic rhinitis and asthma were evaluated using questionnaires and lung function tests.Results There were 35 subjects and four of them dropped outduring the study. There was >50% improvement in allergic rhinitis symptoms after 4 weeks of treatment (P<0.001). This improvement was associated with decreasing in frequency of asthma attack >50% after 8 weeks of treatment (P< 0.001). There was an insignificant improvement in FEY 1 (P=0.51). However, the evaluation of sinusitis was not performed in all subjects, thus may influence the results. During study, there were no side effects observed.Conclusions Intranasal mometasone furoate improves allergicrhinitis and decrease >50% of asthma symptoms, however it is not followed with significant improvement in lung function. No side effects are reported during 8 weeks use of intranasal mometasone furoate.
25
Sausen, Verra O., Katherine E. Marks, Kenneth P. Sausen, and Timothy H. Self. "Management of Allergic Rhinitis." Journal of Pediatric Pharmacology and Therapeutics 10, no. 3 (July 1, 2005): 159–73. http://dx.doi.org/10.5863/1551-6776-10.3.159.
Full textAbstract:
Allergic rhinitis is the most common chronic childhood disease. Reduced quality of life is frequently caused by this IgE-mediated disease, including sleep disturbance with subsequent decreased school performance. Asthma and exercise-induced bronchospasm are commonly seen concurrently with allergic rhinitis, and poorly controlled allergic rhinitis negatively affects asthma outcomes. Nonsedating antihistamines or intranasal azelastine are effective agents to manage allergic rhinitis, often in combination with oral decongestants. For moderate to severe persistent disease, intranasal corticosteroids are the most effiective agents. Some patients require concomitant intranasal corticosteroids and nonsedating antihistamines for optimal management. Other available agents include leukotriene receptor antagonists, intranasal cromolyn, intranasal ipratropium, specific immunotherapy, and anti-IgE therapy.
26
Pal’chun, V. T., A. L. Guseva, Yu V. Levina, and M. L. Derbeneva. "Pharmacotherapy of allergic rhinitis." Meditsinskiy sovet = Medical Council, no. 16 (November 14, 2020): 122–27. http://dx.doi.org/10.21518/2079-701x-2020-16-122-127.
Full textAbstract:
The clinical picture of allergic rhinitis includes sneezing, nasal discharge, impaired nasal breathing, and itching of the nose and roof of mouth. Depending on the duration of symptoms, allergic rhinitis is divided into intermittent and persistent forms, and depending on the severity of symptoms, it can be mild, moderate, and severe. Treatment for allergic rhinitis includes elimination of allergic contacts, allergen-specific immunotherapy, and pharmacotherapy. The choice of a treatment regimen is determined by the severity of symptoms, age of a patient and presence of concomitant diseases. The work is aimed to review the most common pharmaceuticals to treat allergic rhinitis. Saline solutions are used as monotherapy when symptoms are mild, or before use of other topical drugs to clean mucous membranes before their application. Intranasal glucocorticosteroids can be used as monotherapy, if symptoms have different levels of severity, and supplemented with other drugs, in case they are not efficient. Intranasal glucocorticosteroids do not have a systemic effect due to minimal bioavailability. The patients with moderate/severe allergic rhinitis are recommended to use them jointly with second generation antihstamines, intranasal cromones, intranasal antihistamines and leukotriene receptor antagonists. The significant side effect of antihistamines, especially of the first generation, are sedative effects on the central nervous system. The side effects of leukotriene receptor antagonists are neuropsychological disorders. Intranasal cromones have a high safety profile, which makes them popular in paediatric practice. However, the dosage regimen up to 3–4 times a day reduces patient adherence to treatment. Decongestants are not indicated as monotherapy for allergic rhinitis but can be used in combination with other drugs in short courses, taking into account the possible side effects.
27
Rahmawati, Novina, Suprihati Suprihati, and Muyassaroh Muyassaroh. "Faktor risiko yang mempengaruhi disfungsi tuba Eustachius pada penderita rinitis alergi persisten." Oto Rhino Laryngologica Indonesiana 41, no. 2 (December 1, 2011): 142. http://dx.doi.org/10.32637/orli.v41i2.51.
Full textAbstract:
Background: Persistent allergic rhinitis (AR) can lead to Eustachian tuba dysfunction. It could beinfluenced by many factors. Purpose: To prove that AR’s degree, duration, presence of chronic tonsillitisand the use of air conditioner are the risk factors of the Eustachean tube dysfunction in patients withpersistent allergic rhinitis. Method: A cross-sectional study was conducted on patients between 11-54years age who came with persistent AR. Tubal dysfunction was detected by tympanometric examination (MEP negative <-25 mmH2O). The data analysis was analyzed using Chi square test and prevalence ratio. Results: There were 68 subjects. The largest age group was 23-34 years old with mean age is 27.8years. Twenty-six patients (32,8%) with persistent AR had tubal dysfunction. Chi square test for persistentAR’s degree, duration of AR and presence of chronic tonsillitis had no significant relationship with tubaldysfunction. The use of AC was significantly correlated with tubal dysfunction (p>0.05). Multivariatelogistic regression analysis found that it became a risk factor for tubal dysfunction p= 0.019, RP=5.446, CI 95%= 1.321- 22.575. Conclusion: The use of AC becomes a risk factor for tubal dysfunctionin patients with persistent allergic rhinitis. Keywords: persistent allergic rhinitis, Eustachean tube dysfunction, tympanometry Abstrak : Latar belakang: Rinitis alergi (RA) persisten dapat menimbulkan disfungsi tuba Eustachius. Disfungsituba dapat dipengaruhi oleh beberapa faktor. Tujuan: Membuktikan bahwa derajat RA, lama sakit RA,keberadaan tonsiltis kronik dan pemakaian air conditioner (AC) merupakan faktor risiko terjadinyadisfungsi tuba pada penderita rinitis alergi persisten. Metode: Penelitian dengan metode potong-lintangpada RA persisten usia 11-54 tahun. Disfungsi tuba ditentukan dengan pemeriksaan timpanometri (MEPnegatif/<-25 mmH2O). Analisis hasil dengan uji Chi square dan rasio prevalensi. Hasil: Didapatkan68sampel. Usia terbanyak 23-34 tahun, rerata usia 27,8 tahun. Penderita RA persisten dengan disfungsituba 26 (38,2%). Uji Chi square didapatkan derajat RA persisten, lama sakit dan keberadaan tonsilitiskronik tidak mempengaruhi disfungsi tuba (p>0,05). Analisis regresi logistik multivariate didapatkanpemakaian AC secara independen mempunyai risiko terjadinya disfungsi tuba p=0,019, RP=5,446, CI95%= 1,321-22,575. Kesimpulan: Pemakaian AC merupakan faktor risiko terjadinya disfungsi tubapada penderita rinitis alergi persisten. Kata kunci: rinitis alergi persisten, disfungsi tuba, timpanometri
28
A. P., Krithika, Arunkumar T., and Sundari S. "Peak expiratory flow rate assessment to screen for asthma in children with allergic rhinitis." International Journal of Contemporary Pediatrics 5, no. 6 (October 22, 2018): 2278. http://dx.doi.org/10.18203/2349-3291.ijcp20184296.
Full textAbstract:
Background: Allergic rhinitis is a common disease affecting around 10-25% of the population worldwide. There is a temporal relationship between the onset of allergic rhinitis and asthma and the ‘unified airway hypothesis’ explains this. Many researchers have demonstrated bronchial hyper-responsiveness prior to onset of asthma symptoms further validating this hypothesis. Further many studies favour treating allergic rhinitis may prevent the onset of asthma. So, detecting allergic rhinitis earlier and treating it adequately is of vital importance. The aims and objectives of this study is to identify bronchial hyper responsiveness in children with allergic rhinitis, prior to the onset of asthmatic symptoms, by measuring PEFR and its clinical correlates.Methods: A prospective observational study was conducted in Department of Paediatrics in Sree Balaji Medical College and Hospital. Inclusion and Exclusion Criteria were defined, and the study was conducted on a total of 85 children. After taking informed consent from parents, the children coming under the study population were analyzed for their baseline characteristics and PEFR is measured using a low reading Mini Wright peak flow meter and compared with mean value of south Indian children using the formula, PEFR= {(HEIGHT IN CM-100) X5} +100.Results: The mean PEFR as expressed in percentage of expected PEFR is 77.28% in males and 83.34% in females. The mean percentage of expressed PEFR does not vary significantly between different age groups. Of the 85 children,48(56.5%) have mild intermittent allergic rhinitis,28(32.9%) have mild persistent allergic rhinitis,5(5.9%) have moderate-severe intermittent allergic rhinitis and 4(4.7%) have moderate-severe persistent allergic rhinitis. There were 37(43.5%) blockers (with predominant nose block) and 48(56.5%) runners (with predominant rhinorrhea).Conclusions: PEFR is abnormal in 41.2% of children with allergic rhinitis. PEFR reduces linearly as the severity of allergic rhinitis increases. PEFR decreases as the number of cardinal symptoms increases. PEFR increases significantly after treatment of allergic rhinitis alone.
29
Muntean, Ioana Adriana, Ioana Corina Bocsan, Stefan Vesa, Nicolae Miron, Irena Nedelea, Anca Dana Buzoianu, and Diana Deleanu. "Could FeNO Predict Asthma in Patients with House Dust Mites Allergic Rhinitis?" Medicina 56, no. 5 (May 14, 2020): 235. http://dx.doi.org/10.3390/medicina56050235.
Full textAbstract:
Background and Objectives: The evolution of allergic rhinitis to asthma is a part of “atopic march”. The aim of this study was to analyze possible predictive markers for asthma occurrence in patients with allergic rhinitis to house dust mites (HDM). Materials and Methods: Fifty-eight patients with persistent allergic rhinitis (PAR) were included. The clinical, biological evaluation and fractionated exhaled nitric oxide (FeNO) measurement were performed at enrolment. The patients were clinically evaluated after one year to determine asthma occurrence. Results: The severity of rhinitis symptoms, levels of total immunoglobulin E (IgE), ICAM-1, VCAM-1, E-selectin and IL-6, but not IL-8 and TNF-α were higher in patients with allergic rhinitis who developed asthma compared to non-asthmatics, but the differences were not significant to considered them as predictive factors for asthma occurrence. The risk of asthma was independently influenced by patients aged over 30 years ((OR-3.74; CI95% 0.86–16.31; p = 0.07), a duration of allergic rhinitis over 12 months ((OR-4.20; CI95% 0.88–20; p = 0.07) and a basal FeNO over 28 parts per billion (pbb) ((OR-18.68; CI95% 3.79–92.05; p < 0.001). Conclusion: Clinical and biological parameters may predict asthma occurrence in patients with persistent allergic rhinitis to HDM. Adult patients with a longer duration of rhinitis symptoms and a high level of FeNO have a greater risk to develop asthma.
30
&NA;. "Rupatadine realises results for persistent allergic rhinitis." Inpharma Weekly &NA;, no. 1648 (July 2008): 20. http://dx.doi.org/10.2165/00128413-200816480-00072.
Full text
31
Rogkakou, Anthi, Elisa Villa, Valentina Garelli, and G. Walter Canonica. "Persistent Allergic Rhinitis and the XPERT Study." World Allergy Organization Journal 4 (2011): S32—S36. http://dx.doi.org/10.1186/1939-4551-4-s3-s32.
Full text
32
Rogkakou, Anthi, Elisa Villa, Valentina Garelli, and G. Walter Canonica. "Persistent Allergic Rhinitis and the XPERT Study." World Allergy Organization Journal 4, Supplement (March 2011): S32—S36. http://dx.doi.org/10.1097/wox.0b013e318214ba84.
Full text
33
Ciprandi, Giorgio, Ignazio Cirillo, and Angela Pistorio. "Persistent Allergic Rhinitis Includes Different Pathophysiologic Types." Laryngoscope 118, no. 3 (March 2008): 385–88. http://dx.doi.org/10.1097/mlg.0b013e31815dd50b.
Full text
34
Fischer, Axel, Anke Wussow, Annette Cryer, Bernd Schmeck, Oliver Noga, Martina Zweng, Christian Peiser, Q. Thai Dinh, Werner Heppt, and David A. Groneberg. "Neuronal Plasticity in Persistent Perennial Allergic Rhinitis." Journal of Occupational and Environmental Medicine 47, no. 1 (January 2005): 20–25. http://dx.doi.org/10.1097/01.jom.0000150238.77663.49.
Full text
35
Rogkakou, Anthi, Elisa Villa, Valentina Garelli, and G. Canonica. "Persistent Allergic Rhinitis and the XPERT Study." World Allergy Organization Journal 4, Suppl 3 (2011): S32. http://dx.doi.org/10.1097/1939-4551-4-s3-s32.
Full text
36
K. P., Shyna, Veena Kumari M., Divya Krishnan K., and Abdul Azeez V. K. "Clinical profile and skin prick test analysis in children with allergic rhinitis of North Kerala, India." International Journal of Contemporary Pediatrics 5, no. 2 (February 22, 2018): 372. http://dx.doi.org/10.18203/2349-3291.ijcp20180436.
Full textAbstract:
Background: Allergic rhinitis (AR) is increasing in prevalence among children globally and in India. Allergens are factors which trigger allergic rhinitis. Skin prick test (SPT) is a rapid, sensitive and cost effective test to detect IgE- mediated allergic diseases. Identification of common aeroallergens in an area is necessary, in order to educate the patient on what allergens to avoid and also help find the best formulation of allergen immunotherapy for effective AR treatment. This study was done to find the clinical profile and skin sensitivity to common allergens by skin prick test in children with allergic rhinitis between six and fifteen years.Methods: This cross-sectional study was conducted for a period of one year from January 2016 to December 2016. All children between 6 to 15 years with allergic rhinitis were included in the study. Skin prick test was done with seven most common allergens.Results: A total of 60 children with allergic rhinitis were studied and 42 patients (70%) tested positive for SPT. The major symptoms were persistent sneezing (68%), nasal itching (33%), rhinorrhea (85%) and nasal congestion (42%). The proportion of sneezers-runners was higher than blockers (64% versus 36). We tested seven common allergens and house dust mite allergen yielded the highest number of positive responses (33%) followed by cockroach (25%), alternaria (16.66%), parthenium (10%), cat dander (8.35%), sorghum (5%) and dog dander (5%). Among patients with SPT positivity; eight were positive to one allergen, thirteen were positive to two allergens, sixteen to three allergens and five to four allergens.Conclusions: Allergic Rhinitis with a number of allergic co morbidities has a significant impact on the quality of life and scholastic performance in children. Skin prick test which is a standardized, most rapid, sensitive and cost-effective test to detect IgE-mediated allergic diseases is helpful in identifying the common allergens. House dust mite is the commonest allergen tested positive in our study in children.
37
Koruga, Dragan, Nenad Baletic, Kristina Tot-Veres, and Aleksandar Peric. "Impulse oscillometry in evaluation bronchial hyperresponsivness in patients with persistent allergic rhinitis." Vojnosanitetski pregled 75, no. 1 (2018): 39–45. http://dx.doi.org/10.2298/vsp160407236k.
Full textAbstract:
Background/Aim. Impulse oscillometry (IOS) is a method for estimating lung function which is used for early detection of bronchial hyperresponsiveness (BHR) and asthma. The aim of the study was to determine the prevalence of BHR, the correlation between spirometry and IOS and sensitivity and specificity of IOS in proving BHR in patients with persistent allergic rhinitis. Methods. The study included 81 patients with allergic rhinitis. From all of them, medical history was taken, allergy testing was done, as well as measurements of parameters of lung function by the IOS and spirometry before and after nonspecific bronchial provocation test with histamin via Aerosol provocative system. Changes of the IOS parameters to fall in FEV1 of 20% were measured and compared with changes in the spirometry parameters. After bronchial challenge test subjects were divided into two groups: the group with BHR (group 1) and that without BHR (group 2). Results. The mean age of participants was 25.7 ? 5.7 years, and 50.5% were men. Out of the total number of subjects with allergy rhinitis, 56 (58.9%) had a positive BPT. After bronchoprovocation an average increase in the group 1 was 88.15% for Rrs5, 111.98% for Fres, and for AX 819.69%. The high degree of correlation between the IOS and spirometry was proven in the group 2, while the whole group 1 had a weak correlation between parameters of these two methods. High sensitivity and low specificity for Rrs5 and Fres compared to FEV1 in diagnosing BHR was proven. Conclusion. The study demonstrated a high prevalence of BHR in the study group of patients with persistent allergic rhinitis, poor correlation in relation to the spirometric measurements in the group with BHR and a high sensitivity and low specificity of IOS for the detection of early changes in the airways.
38
Svistushkin, V. M., G. N. Nikiforova, P. S. Artamonova, and E. A. Shevchik. "Modern possibilities of pathogenetic therapy of patients with allergic rhinitis." Meditsinskiy sovet = Medical Council, no. 6 (May 27, 2020): 101–6. http://dx.doi.org/10.21518/2079-701x-2020-6-101-106.
Full textAbstract:
The incidence of allergic rhinitis has been increasing rapidly worldwide in recent years. About 40% of the world’s population suffer from allergic inflammation of the nasal mucous membrane. Clinical manifestations of allergic rhinitis are absence or difficulty of nasal breathing, itching, sneezing, nasal congestion and rhinorrhoea, as well as swelling of the face, the presence of dermatitis in the region of the nasal wings, general malaise, smell disturbance. Manifestations of allergies by ENT organs in most cases do not pose a threat to life, but they can cause the development of other pathological processes, bad sleep, irritability, decreased efficiency, mood swings, which, in turn, adversely affects human health and reduces the quality of life. The pathogenesis of allergic rhinitis is based on an immediate hypersensitivity. According to the modern classification, depending on the nature of the course of the disease it is common to identify intermittent and persistent forms.At present, the drugs of choice in the treatment of patients with allergic rhinitis are intranasal glucocorticosteroids. However, the presence of a concomitant pathology of the nasal cavity in the patient, such as deviated septum, not only significantly impairs the course of nasal inflammatory process, but also creates obstacles to adequate delivery of topical drugs to all parts of the nasal cavity, which, in turn, reduces their effectiveness.For patients suffering from allergic rhinitis in combination with other pathology of the nasal cavity, combined oral medications may be a good alternative to intranasal sprays. Certain interest for doctors is caused by the appearance of a combined antihistamine drug on the Russian market, which includes a blocker of leukotrienes and H1-histamine receptors of the second generation – montelukast and levocetirizine. The drug can be used both in adults and children from 15 years old for treatment of intermittent and persistent forms of allergic rhinitis.Timely and properly performed therapy of allergic rhinitis allows to eliminate symptoms of the disease and prevent the development of complications.
39
Bogomolov, Artemy Ye, and Lyudmila I. Dubchak. "Comparison of diagnostic parameters of methods for determination of sensitization to allergen D. pteronyssinus in patients with respiratory allergic diseases." OTORHINOLARYNGOLOGY, no. 4-5(2) 2019 (March 12, 2020): 19–26. http://dx.doi.org/10.37219/2528-8253-2019-4-19.
Full textAbstract:
The aim of the study was to evaluate the diagnostic parameters of various methods for determining allergy sensitization to the dust mite allergen Dermatophagoides pteronyssinus in patients with respiratory allergic diseases – allergic rhinitis and bronchial asthma. Materials and methods: During the study, 88 patients with allergic rhinitis and / or atopic asthma were examined with three different methods of specific allergic diagnosis (in vivo and in vitro) according to the recommendations of the ethics committee of the Pirogov Vinnitsa National Medical University, all of which were out of acute period. Inclusion criteria were a diagnosis of allergic rhinitis (both intermittent and persistent) and / or atopic asthma. The prick-test was conducted according to the classic test method by normative documents with commercial allergen extracts. Western blots for the determination of IgE levels were performed using RIDA AllergyScreen test systems (R-Biopharm AG, Darmstadt, Germany) and Euroline (Euroimmun). Results and discussion: The results of two systems for the determination of specific IgE to D. Pteronyssinus by the Rida AllergyScreen and Euroline methods have a systematic difference of values (-1.27 kU / l). There is a good agreement between the results of skin testing with D. Pteronyssinus allergens and the detection of specific IgE by the Rida AllergyScreen method, and there is a satisfactory agreement between the results of skin testing with D. Pteronyssinus allergens and detection of specific IgE by the Euroline method. According to the results of the curve of detection of specific IgE by AllergyScreen method for determination of sensitization to allergen D. Pteronyssinus has excellent diagnostic significance (AUC=0,953), detection of specific IgE by Euroline method for determination of sensitization to allergen D. Pteronyssinus – good AUC=0,7.
40
Kambatatti Shekharappa, Munish, and Rohini D. Urs. "A cross sectional observational study of severity of allergic rhinitis and its impact on asthma." International Journal of Otorhinolaryngology and Head and Neck Surgery 6, no. 3 (February 24, 2020): 547. http://dx.doi.org/10.18203/issn.2454-5929.ijohns20200633.
Full textAbstract:
<p class="abstract"><strong>Background:</strong> Allergic rhinitis (AR) and asthma are chronic diseases that often coexist and whose prevalence is increasing day by day. Uncontrolled allergic rhinitis may be associated with worsening of asthma and hence optimal treatment of AR may improve the coexisting asthma. The objective of the study was to study the severity of allergic rhinitis and its impact on asthma.</p><p class="abstract"><strong>Methods:</strong> A cross sectional study was conducted on 60 patients, at our Institute from November 2017 to June 2019 who were clinically diagnosed to have AR and asthma. Patients were evaluated by proper history taking, in detailed clinical examination and diagnostic nasal endoscopy and spirometry. </p><p class="abstract"><strong>Results:</strong> In our study out of 60 patients, majority fell in 20 to 40 age group. According to allergic rhinitis and its impact on asthma (ARIA) classification 10 (17%) had mild intermittent AR, 12 (20%) had mild persistent AR, 5 (8%) had moderate/severe intermittent AR and 33 (55%) had moderate or severe persistent AR. In case of moderate/severe persistent AR: 4 had intermittent, 9 had mild persistent, 10 had moderate persistent and 10 severe persistent asthma. Spearman’s rank correlation was done between severity of AR and severity of asthma, spearman’s rho: 0.365, p<0.004 was significant.</p><p class="abstract"><strong>Conclusions:</strong> We noted that as the severity of allergic rhinitis increased, severity of asthma also increased, which was a linear correlation.</p>
41
Choudhary, Sadaf, Keya Rani Lahiri, and Fehmida Najmuddin. "Correlation of Height Parameter and Pulmonary Function Test with Grade of Allergic Rhinitis and Asthma in Children." International Journal of Innovative Research in Medical Science 5, no. 08 (August 16, 2020): 349–52. http://dx.doi.org/10.23958/ijirms/vol05-i08/937.
Full textAbstract:
Introduction: Allergic Rhinitis and Asthma adversely affects height in children and it could be considered as an objective tool to assess severity, compliance and lung functions in children. We studied the correlation between height and pulmonary function tests with classification of allergic rhinitis and asthma. Aims & Objectives: 1) To study the height parameter with the grade of asthma and allergic rhinitis 2) To evaluate the pulmonary function test with the severity of asthma and allergic rhinitis 3) To correlate height and pulmonary function test with the classification of asthma and allergic rhinitis. Material and Methods: A prospective study including 30 patients in the age group of 5-12 years diagnosed with allergic rhinitis (AR) and bronchial asthma was conducted in a private tertiary care hospital in Navi Mumbai. History was entered in a pre-designed proforma and height was measured using a calibrated stadiometer along with pulmonary function tests recorded at the initial and two visits, 3 months apart. Results: Height increased significantly in patients without AR (p-value<0.01), with mild intermittent (p-value=0.02) and mild persistent AR (p-value<0.01) on subsequent visits. Patients with intermittent, mild persistent and moderate persistent asthma showed a statistically significant increase in height (p-value<0.01) with subsequent assessments. No significant increase in height was noted in patients with moderate persistent AR (p-value=0.14) and severe persistent asthma (p-value=0.16). At baseline, the height correlated significantly with FEV1 (p value<0.01), FVC (p value<0.01), Pre and Post-PEFR (p value<0.01, each). This trend continued at the first follow up. At the second follow-up, height correlated significantly with all parameters of pulmonary function tests (p value<0.01 for FEV1, FVC, FEV1/FVC ratio and PEFR). Conclusion: Height correlation with classification of AR and Asthma along with pulmonary function test has emerged as a simple, safe, cost-effective method in assessing control and monitoring the disease.
42
Endre, László. "Occupational rhinitis and allergic conjunctivitis." Orvosi Hetilap 155, no. 5 (February 2014): 170–75. http://dx.doi.org/10.1556/oh.2014.29786.
Full textAbstract:
Occupational rhinitis is an inflammatory disease of the nose, which is characterised by intermittent or persistent symptoms, arising from causes and conditions attributable to a particular work environment and not from stimuli encountered outside the workplace. Its clinical symptoms such as nasal congestion, sneezing, rhinorrhoea, itching, nasal airflow limitation are very similar to the symptoms of allergic rhinitis caused by other (classical) agents. Occupational allergic conjunctivitis is an IgE mediated disease, provoked by a substance in the air of the workplace. Its clinical signs (itching, tearing, conjunctival hyperaemia and oedema and, in some cases when the cornea is also involved, blurred vision, photosensitivity) are similar to other forms of allergic conjunctivitis. Risk factors (which in most of the cases occur in both diseases) include history of atopy, high concentration of the irritant agent and multiple irritant agents in the air of the workplace. Atopy has been associated with an increased risk of specific sensitisation to a variety of high molecular weight agents. For the diagnosis of occupational rhinitis and occupational allergic conjunctivitis objective investigations such as allergen specific provocations are necessary in addition to clinical and occupational history. Management of these occupational diseases needs environmental interventions (increasing ventilation, decreasing the time of exposure, substitution of the irritant agent). Medical treatment of occupational rhinitis is very similar to other allergic diseases: oral antihistamines, local (nasal) corticosteroids, combined (antihistamine plus membrane stabilizer) eyedrops. The most important step in medical treatment of occupational allergic conjunctivitis is the daily application of combined eyedrops (for example: olopatadine). Orv. Hetil., 2014, 155(5), 170–175.
43
Sheahan, P., R. McConn-Walsh, M. Walsh, and R. W. Costello. "The Allergic Rhinitis and its Impact on Asthma system: a new classification of allergic rhinitis and nasal responsiveness." Journal of Laryngology & Otology 122, no. 3 (May 14, 2007): 259–63. http://dx.doi.org/10.1017/s0022215107008298.
Full textAbstract:
AbstractObjectives and hypothesis:Allergic rhinitis has traditionally been classified into seasonal and perennial rhinitis. However, many subjects with dual sensitisation do not fit neatly into either category. Recently, the Allergic Rhinitis and its Impact on Asthma workshop has proposed a new allergic rhinitis classification, into intermittent and persistent forms. The purpose of the present study was to investigate whether the symptomatic and secretory responsiveness of allergic rhinitis sufferers correlated well with the Allergic Rhinitis and its Impact on Asthma classification, compared with the traditional classification.Study design:Experimental study.Methods:Forty subjects with allergic rhinitis and 13 normal controls underwent a unilateral nasal bradykinin challenge protocol. Symptom scores were recorded and secretion weights measured bilaterally using filter paper disks. The symptomatic and secretory responses of allergic subjects were analysed according to both the traditional and the Allergic Rhinitis and its Impact on Asthma classifications, and the two systems were compared.Results:For both classification systems, the two groups of allergic subjects were clearly demarcated by secretory responses. However, after classification according to the traditional system, there was a lack of clear demarcation between the groups as regards symptomatic response, whereas clear demarcation of symptomatic responses was seen after using the Allergic Rhinitis and its Impact on Asthma classification.Conclusions:In allergic rhinitis subjects, the degree of nasal responsiveness was closely related to their Allergic Rhinitis and its Impact on Asthma classification. Furthermore, this classification was not compromised by the inclusion of subjects with dual sensitisation. Thus, the Allergic Rhinitis and its Impact on Asthma classification may have advantages for future research studies on allergic rhinitis.
44
Widuri, Asti, and Lilis Suryani. "The Effects of Probiotic Lactobacillus casei Shirota Strain in Patients with Allergic Rhinitis Symptoms." International Journal of Public Health Science (IJPHS) 4, no. 4 (December 1, 2015): 264. http://dx.doi.org/10.11591/ijphs.v4i4.4744.
Full textAbstract:
Allergic rhinitis is inflammatory reactions mediated by immunoglobulin E, after exposure to allergens. The symptoms are sneezing, runny nose and nasal congestion. Allergic rhinitis can be alleviated by the use of specific probiotics selected to confer immune effects, which can be demonstrated in the intestinal tract prior to an allergic reaction. The specific strains used in this study were selected based on their anti-inflammatory properties and an expected effect in promoting a Th1 type of immune response. To review the benefits of probiotics of Lactobacillus casei L Shirota strain in preventing allergy attacks that inhibit the production of IgE, IL-4 and reduce the symptoms. To review the benefits of probiotics of Lactobacillus casei L Shirota strain in preventing allergy attacks that inhibit the production of IgE, IL-4 and reduce the symptoms. The study design was quasi-experimental with pre and post test design. The subject were 45 patients who had a history of allergic rhinitis and positif skin prickt test result and filled out the questionnaires to get the allergic symptoms. The blood samples were taken for examining the IgE and IL-4 levels then after giving milk containing probiotics for 1 month, the researcher did the same examination. The mean IgE and IL-4 levels decrease before and after supplementation probiotics from 291.88 IU / L and 22.48 pg/ml to 141.43 IU / L and 17.83 pg/ml. The result of the statistical analysis paired t-test test was p = 0.00 on IgE level and p=0,056 on IL-4 level. The allergic rhinitis symptoms decreased significantly, the presentage of patients who had persistent and moderate 17.78% to 0% , who had persistent and mild 44.44% to 4.44%, who had intermittent and moderate 13.33% to 2.22%,and who had intermittent and mild 24.44% to 93.33%. Based on the Wilcoxon signed rank test showed a significance value of P = 0.00. Conclusion Probiotics is useful in preventing allergy attacks that inhibit the production of IgE, IL-4 and reduce the symptoms.
45
Widuri, Asti, and Lilis Suryani. "The Effects of Probiotic Lactobacillus casei Shirota Strain in Patients with Allergic Rhinitis Symptoms." International Journal of Public Health Science (IJPHS) 4, no. 4 (December 1, 2015): 264. http://dx.doi.org/10.11591/.v4i4.4744.
Full textAbstract:
Allergic rhinitis is inflammatory reactions mediated by immunoglobulin E, after exposure to allergens. The symptoms are sneezing, runny nose and nasal congestion. Allergic rhinitis can be alleviated by the use of specific probiotics selected to confer immune effects, which can be demonstrated in the intestinal tract prior to an allergic reaction. The specific strains used in this study were selected based on their anti-inflammatory properties and an expected effect in promoting a Th1 type of immune response. To review the benefits of probiotics of Lactobacillus casei L Shirota strain in preventing allergy attacks that inhibit the production of IgE, IL-4 and reduce the symptoms. To review the benefits of probiotics of Lactobacillus casei L Shirota strain in preventing allergy attacks that inhibit the production of IgE, IL-4 and reduce the symptoms. The study design was quasi-experimental with pre and post test design. The subject were 45 patients who had a history of allergic rhinitis and positif skin prickt test result and filled out the questionnaires to get the allergic symptoms. The blood samples were taken for examining the IgE and IL-4 levels then after giving milk containing probiotics for 1 month, the researcher did the same examination. The mean IgE and IL-4 levels decrease before and after supplementation probiotics from 291.88 IU / L and 22.48 pg/ml to 141.43 IU / L and 17.83 pg/ml. The result of the statistical analysis paired t-test test was p = 0.00 on IgE level and p=0,056 on IL-4 level. The allergic rhinitis symptoms decreased significantly, the presentage of patients who had persistent and moderate 17.78% to 0% , who had persistent and mild 44.44% to 4.44%, who had intermittent and moderate 13.33% to 2.22%,and who had intermittent and mild 24.44% to 93.33%. Based on the Wilcoxon signed rank test showed a significance value of P = 0.00. Conclusion Probiotics is useful in preventing allergy attacks that inhibit the production of IgE, IL-4 and reduce the symptoms.
46
Monga, Seema, Junaid Malik, Arun Parkash Sharma, Sabeena Jan, Nighat Nabi, and Sudhir Bahadur. "Deranged Pulmonary Function Tests in Allergic Rhinitis in North Indian Patients." Clinical Medicine Insights: Ear, Nose and Throat 12 (January 2019): 117955061988885. http://dx.doi.org/10.1177/1179550619888856.
Full textAbstract:
Introduction: Significant associations between allergic rhinitis and bronchial asthma have been established and as a result of bronchial hyper-responsiveness, patients can have deranged pulmonary function tests. We aim to compare previous such studies with the result of our study done in India wherein we identify among allergic rhinitis patients who despite not having overt asthmatic symptoms, have pulmonary function derangements, quite possibly at a subclinical disease level. Materials and Methods: We studied 74 patients of allergic rhinitis and after meticulous clinical work up, they underwent blood tests including hemogram, absolute eosinophil count, and total serum IgE followed by pulmonary function tests. Results: Out of 74 patients 60 (81%) had intermittent allergic rhinitis whereas only 14 (19%) had persistent allergic rhinitis. Pulmonary function tests showed reversible obstruction, ie, >10% improvement in FEV1 with inhaled bronchodilators (as seen in asthma) in 18 (24.3%), mild obstruction in 14, and moderate obstruction in 4 cases. Conclusion: The study emphasizes the importance of pulmonary symptoms and the performance of pulmonary function tests in cases of allergic rhinitis patients to rule out latent asthma.
47
Virtuoso, João, Íris Santos Silva, Pedro Guerra, and Rita S. Oliveira. "A complexidade em alergologia pediátrica: o doente polissensibilizado." Scientia Medica 29, no. 4 (December 6, 2019): 33629. http://dx.doi.org/10.15448/1980-6108.2019.4.33629.
Full textAbstract:
AIMS: In the present study, the authors intend to demonstrate the advantages of molecular diagnosis in immunoallergology through the description of a clinical case.CASE DESCRIPTION: We present the case of a 9-year-old male, followed by pediatric immunoallergology with the diagnoses of moderate persistent asthma, persistent rhinitis, atopic eczema and food allergy with severe manifestations (several episodes of anaphylaxis). molecular profile of allergic sensitization contributed to better knowledge of the patient, therapeutic and even prognostic adequacy.CONCLUSIONS: The molecular allergy diagnostic tests, according to the analysis of the present case, allows the establishment and escalation in terms of severity of a more individualistic sensitization profile, which is especially important in the patient who is polysensitized and with reports of respiratory and food allergies.
48
Gunhan, Kivanc, Halis Unlu, Ali Vefa Yuceturk, and Murat Songu. "Radiofrequency tissue ablation treatment in persistent allergic rhinitis." World Allergy Organization Journal &NA; (November 2007): S76—S77. http://dx.doi.org/10.1097/01.wox.0000301342.51731.c5.
Full text
49
Braido, F., I. Baiardini, N. Scichilone, A. Musarra, S. Menoni, E. Ridolo, F. Gani, et al. "Illness perception, mood and coping strategies in allergic rhinitis: are there differences among ARIA classes of severity?" Rhinology journal 52, no. 1 (March 1, 2014): 66–71. http://dx.doi.org/10.4193/rhino13.040.
Full textAbstract:
Background: This study was designed to assess if illness perception, mood state and coping strategies differ according to allergic rhinitis (AR) persistence and severity. Methods: Illness perception, mood profiles, coping behaviors and rhinitis symptoms were assessed by means of validated tools inpatients classified according to the Allergic Rhinitis and Its Impact on Asthma (ARIA) guidelines. Results: Two hundred and thirty-one patients underwent data analysis. No difference in age, sex, socio-economic status, smoking habits was detected comparing patients according to AR severity, duration or 4 ARIA classes. Patients with intermittent AR reported higher scores than those with persistent AR in confusion-bewilderment of Profile of Mood States (POMS); patients with moderate/severe rhinitis had significantly higher scores than those with mild rhinitis in TSSS, Identity and Consequences. No differences were detected in all assessed outcomes in the 4 ARIA classes. Conclusions: The patient's perspective about AR is independent of persistence and severity of symptoms. This may explain why AR remains under-diagnosed and under-treated, even in its most severe forms. Self-management plans should consider the patient's perspective.
50
Krivopalov, A. A., S. A. Rebrova, and P. A. Shamkina. "Features of the modern antihistamines use in the treatment of allergic rhinitis." Meditsinskiy sovet = Medical Council, no. 12 (September 19, 2021): 101–8. http://dx.doi.org/10.21518/2079-701x-2021-12-101-108.
Full textAbstract:
Allergic rhinitis remains one of the most relevant problems of modern otorhinolaryngology. The widespread prevalence, late diagnosis, underestimation of the possible risks of disease progression, the development of complications (including asthma) prompts the development and improvement of new treatment options for allergic rhinitis. Allergic rhinitis is a heterogeneous disease that presents with various clinical phenotypes, and therefore the severity of nasal symptoms can vary from mild malaise to severe disease.. Today, pharmacotherapy remains the most frequently used treatment tactic for patients with allergic rhinitis. While prescribing therapy the doctor develops an individual treatment plan based on the principles of personalized medicine, considering: the dominant symptoms, anamnesis data on previous therapy and the effect of treatment, the type of inflammation (Th2-type, mixed inflammation), concomitant diseases (conjunctivitis, asthma, etc.) etc.) and patient preferences. The tissue effects of the histamine mediator lead to the development of symptoms during the course of the disease, which determines the wide-spread use of antihistamines in the treatment of rhinitis. Antihistamines of the second generation are devoid of sedative effects, have a long-lasting effect and a good safety profile. One of the modern II generation antihistamines is bilastine. The research results proved the high antihistaminic activity of bilastine 20 mg in vitro and in vivo, the absence of cardiac and sedative side effects on the central nervous system, the ability to eliminate the nasal and ocular symptoms of disease and improve the quality of life of patients with allergic rhinitis. Thus, bilastine fully complies with current EAACI / WAO ARIA requirements for drugs used to treat AR. The paper presents a clinical case of a patient with chronic persistent allergic rhinitis, household sensitization with a slight uncontrolled course. The oral antihistamine bilastine was added to intranasal glucocorticosteroids, which help to relieve symptoms of the disease, stabilize the condition and prepare the patient for subsequent allergen-specific immunotherapy.