Academic literature on the topic 'Peritoneal dialysis'

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Journal articles on the topic "Peritoneal dialysis"

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Nakamoto, Hidetomo, Hiroe Imai, Yuji Ishida, Yasuhiro Yamanouchi, Tsutomu Inoue, Hirokazu Okada, and Hiromichi Suzuki. "New Animal Models for Encapsulating Peritoneal Sclerosis—Role of Acidic Solution." Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis 21, no. 3_suppl (December 2001): 349–53. http://dx.doi.org/10.1177/089686080102103s64.

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Objective Encapsulating peritoneal sclerosis (EPS), in which all or part of the intestine is enveloped in a fibrous ball resembling a cocoon, is a serious complication of peritoneal dialysis (PD). The aim of the present study was to investigate whether pH-neutral or acidic dialysis solutions induce peritoneal fibrosis. Design We divided 18 male Wistar–Kyoto (WKY) rats into three groups and dialyzed them with various solutions as follows: group I, 10 mL acidic dialysis solution (pH 3.8, containing 1.35% glucose), n = 6; group II, 10 mL pH 5.0 dialysis solution, n = 6; and group III, 10 mL neutral dialysis solution (pH 7.0), n = 6. Peritoneal catheters were inserted, and dialysis solution was injected every day for 40 days. At the end of the experiment, a peritoneal equilibration test (PET) was performed. Expression of mRNA of aquaporins 1 and 4 (AQP-1 and AQP-4) in the peritoneum were studied by semiquantitative reverse-transcriptase polymerase chain reaction (RT-PCR). Results In rats treated with pH 3.8 dialysis solution, necropsy findings revealed features identical to those of EPS. The typical appearance was of granulation tissue or fibrotic tissue (or both) covering multiple surfaces. Multiple adhesions were present. In microscopic examinations, peritoneal fibrosis and loss of mesothelium were found. In rats treated with pH 7.0 dialysis solution, no signs of EPS were seen. In rats treated with pH 5.0 dialysis solution, milder changes (subserosal thickening and partial adhesion of the peritonea) were observed. The mRNA of AQP-1 and AQP-4 were expressed in the peritonea of the rats. The expression of the AQPs was significantly suppressed in rats treated with pH 3.8 dialysis solution. Conclusions In rats, long-term intraperitoneal injection of acidic dialysis solution produced features typical of EPS in humans. Newly developed neutral dialysis solutions protected the against the development of EPS during peritoneal dialysis in rats.
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Andreoli, Maria Claudia Cruz, and Claudia Totoli. "Peritoneal Dialysis." Revista da Associação Médica Brasileira 66, suppl 1 (2020): s37—s44. http://dx.doi.org/10.1590/1806-9282.66.s1.37.

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SUMMARY Peritoneal dialysis (PD) is a renal replacement therapy based on infusing a sterile solution into the peritoneal cavity through a catheter and provides for the removal of solutes and water using the peritoneal membrane as the exchange surface. This solution, which is in close contact with the capillaries in the peritoneum, allows diffusion solute transport and osmotic ultrafiltration water loss since it is hyperosmolar to plasma due to the addition of osmotic agents (most commonly glucose). Infusion and drainage of the solution into the peritoneal cavity can be performed in two ways: manually (continuous ambulatory PD), in which the patient usually goes through four solution changes throughout the day, or machine-assisted PD (automated PD), in which dialysis is performed with the aid of a cycling machine that allows changes to be made overnight while the patient is sleeping. Prescription and follow-up of PD involve characterizing the type of peritoneal transport and assessing the offered dialysis dose (solute clearance) as well as diagnosing and treating possible method-related complications (infectious and non-infectious).
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Lu, Jingyuan, Danye Shi, Xinhui Zhao, Minhui Xi, Hualin Qi, and Qiang He. "Crocin ameliorates peritoneal fibrosis in rat induced by peritoneal dialysis via Wnt5a/β-Catenin pathway." Quality Assurance and Safety of Crops & Foods 14, no. 4 (September 1, 2022): 36–44. http://dx.doi.org/10.15586/qas.v14i4.1151.

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Peritoneal dialysis is used in the treatment of patients with kidney diseases. Long-term peritoneal dialysis could result in peritoneal fibrosis and recurrent peritonitis, thus leading to failure of ultrafiltration. Crocin is a bioactive carotenoid and isolated from stigma of Crocus sativus, and ameliorates pulmonary and myocardial fibrosis. The role of crocin in peritoneal fibrosis was assessed. Firstly, rats model with peritoneal dialysis was treated with 4.25% peritoneal dialysate. Results showed that injection with peritoneal dialysate induced obvious hyperplasia and increased thickness in peritoneum structure. Rats with peritoneal dialysis were injected with increasing concentrations of crocin at 10, 20, or 40 mg/kg. Crocin ameliorated the pathological changes in the peritoneum of peritoneal dialysate-induced rats. Secondly, crocin attenuated peritoneal dialysate-induced decrease of E-cadherin, increase of fibronectin, α-smooth muscle actin (α-SMA), and collagen I. Moreover, crocin enhanced ultrafiltration volume and reduced glucose transport in rats model with peritoneal dialysis. Thirdly, crocin also reduced levels of Interleukin (IL)-1β, Tumor Necrosis Factor-α (TNF –α), and IL-6 in peritoneal tissues of rats model with peritoneal dialysis. Lastly, protein expression of Wnt5a and β-Catenin in rats model with peritoneal dialysis were also downregulated by crocin. In conclusion, crocin exerted anti-inflammatory and anti-fibrotic effects on rats model with peritoneal dialysis through inactivation of Wnt5a/β-Catenin pathway.
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Sulowicz, Wladyslaw, Tadeusz Cichocki, and Zygmunt Hanicki. "Changes in Activity of Selected Lysosomal Enzymes in Peritoneal Macrophages of Renal Failure Patients on Peritoneal Dialysis." Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis 9, no. 4 (October 1989): 313–17. http://dx.doi.org/10.1177/089686088900900417.

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Activity of acid phosphatase (AP), beta-glucuronidase (GR), N-acetyl-beta-D-glucosaminidase (GZ), and peroxidase (P) was assessed using a semiquantitative cytochemical method in peritoneal macro phages of 30 patients with end-stage renal failure treated by intermittent peritoneal dialysis and of 30 control patients with normal renal function. The dialysed patients showed a significantly higher activity of GR and P at the beginning of the treatment as compared with the respective activities observed in the control group and a further significant rise of these activities after 4 months of dialysis. Activity of AP at the beginning of the treatment was insignificantly lower than in the control group and the difference became significant at the end of the investigated period. There was no significant difference between the dialysed patients and the control group in the activity of GZ assessed at the beginning of the dialytic treatment and after 4 months of dialysis. A significant decrease in that activity was, however, observed in the course of dialysis.
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Wieczorowska-Tobis, K., K. Korybalska, A. Polubinska, M. Radkowski, A. Breborowicz, and D. G. Oreopoulos. "In Vivo Model to Study the Biocompatibility of Peritoneal Dialysis Solutions." International Journal of Artificial Organs 20, no. 12 (December 1997): 673–77. http://dx.doi.org/10.1177/039139889702001203.

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This study was designed to analyze the complex morphologic and functional effects of dialysis solutions on peritoneum in a rat model on chronic peritoneal dialysis. Peritoneal catheters were inserted into 10 male, Wistar rats and the animals were dialyzed twice daily for 4 weeks with 4.25% Dianeal. During the study we observed two opposite effects: healing of the peritoneum after catheter implantation - decreased cell count in dialysate, decreased permeability of the peritoneum to glucose and total protein, increased volume of drained dialysate; and damage to the membrane due to its exposure to peritoneal dialysis solution - increased hyaluronic acid levels in dialysate, a tendency of the peritoneum to thicken when compared to non-dialyzed animals. Our rat model of CAPD may be used for quantitative and qualitative assessment of the effects of peritoneal dialysis solution on the peritoneum during chronic dialysis
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Wu, George, Katarzyna Wieczorowska Tobis, Alicja Polubinska, Katarzyna Korybalska, Violetta Filas, Paul Tam, Ian French, and Andrzej Breborowicz. "N-Acetylglucosamine Changes Permeability of Peritoneum during Chronic Peritoneal Dialysis in Rats." Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis 18, no. 2 (March 1998): 217–24. http://dx.doi.org/10.1177/089686089801800212.

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Objective To evaluate the effect of supplementation of dialysis fluid with N-acetylglucosamine (NAG) on the permeability of peritoneum during chronic peritoneal dialysis in rats. Design Experiments were performed on rats with surgically implanted peritoneal catheters. Dialysis solution [DianeaI1.5% (Baxter, Deerfield, IL, U.S.A.) supplemented with either NAG 50 mmol/L or glucose 50 mmol/L (control)] was infused intraperitoneally twice, every day, for 8 weeks. Peritoneal equilibration tests (PET) were performed in all animals at the beginning of the study and after 8 weeks of dialysis. Additionally, at the end of each week, dialysis solution infused in the morning was drained after 4 hours of intraperitoneal dwell. White blood cell count, creatinine, and total protein concentrations were measured in the effluent dialysate. After 8 weeks of dialysis, the morphology of the peritoneum was studied. Results In rats exposed to dialysis fluid supplemented with NAG, peritoneal permeability to creatinine and proteins was reduced when compared to animals dialyzed with glucose solution. In NAG treated animals, staining with alcian blue for polyanions in the peritoneal interstitium was significantly stronger than in rats dialyzed with glucose solution. Conclusions Chronic peritoneal dialysis with dialysis solution supplemented with N-acetylglucosamine causes accumulation of glycosaminoglycans in the peritoneal interstitium, which results in a change of peritoneal permeability.
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Kostović, Milica, Milica Cvetkovic, and Dejan Petrovic. "Gastrointestinal Non-Infectious Complications in Patients on Peritoneal Dialysis." Serbian Journal of Experimental and Clinical Research 17, no. 2 (June 1, 2016): 153–60. http://dx.doi.org/10.1515/sjecr-2015-0039.

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Abstract Gastrointestinal complications are common among patients on peritoneal dialysis. Risk factors for the development of gastrointestinal complications in this patient population include: toxic effects of uremic toxins, frequent use of nonsteroidal anti-inflammatory drugs, Helicobacter pylori infection, angiodysplasia, increased intra-abdominal pressure, use of bioincompatible solution for peritoneal dialysis, increased glucose in solutions for peritoneal dialysis, secondary hyperparathyroidism (hypercalcemia), a disorder of lipid metabolism (hypertriglyceridemia), and the duration of peritoneal dialysis treatment. The most important non-infectious gastrointestinal complications in patients on peritoneal dialysis are: gastrointestinal bleeding, herniation and leaking of the dialysate from the abdomen (increased intra-abdominal pressure), impaired lung function (intra-abdominal hypertension), acute pancreatitis, and encapsulating sclerosis of the peritoneum. Intra-abdominal hypertension is defined as IAP ≥ 12 mmHg. Pouring the peritoneal dialysis solution leads to increased intra-abdominal pressure, which results in the development of hernias, pleuro-peritoneal dialysate leakage (hydrothorax), and restrictive pulmonary dysfunction. Risk factors for the development of acute pancreatitis in this patient population include: uraemia, secondary hyperparathyroidism with hypercalcemia, hypertriglyceridemia, features of the peritoneal dialysis solution (osmolarity, acidity, glucose, chemical irritation, and calcium in the solution for peritoneal dialysis lead to “local hypercalcemia”), toxic substances from the dialysate, the bags and tubing, and peritonitis and treatment of peritonitis with antibiotics and anticoagulants. Encapsulating sclerosis of the peritoneum is rare and is the most serious complication of long-term peritoneal dialysis. It is characterized by thickening of the peritoneum, including cancer, and signs and symptoms of obstructive ileus. Diagnosis is based on clinical, laboratory and radiological parameters. Encapsulating sclerosis of the peritoneum can be indicated by an AR-CA-125 concentration of less than 33 U/min and a concentration of AR-IL-6 greater than 350 pg/min in the effluent of patients with ultrafiltration weakness. Treatment consists of stopping peritoneal dialysis, using anti-inflammatory (corticosteroids) and anticicatricial drugs (tamoxifen), while surgical treatment includes enterolysis and adhesiolysis.
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Djurdjevic-Mirkovic, Tatjana. "Peritoneal dialysis - experiences." Medical review 63, no. 11-12 (2010): 753–57. http://dx.doi.org/10.2298/mpns1012753d.

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Peritoneal dialysis is the method of treatment of terminal-stage chronic kidney failure. Nowadays, this method is complementary to haemodialysis. It is based on the principles of the diffusion of solutes and ultrafiltration of fluids across the peritoneal membrane, which acts as a filter. The dialysate is introduced into the peritoneum via the previously positioned peritoneal catheter. The peritoneal dialysis is carried out on daily basis, at home by the patient, and the ?exchange? is repeated 4-5 times during the 24 hours. The first steps in peritoneal dialysis at the Department for Haemodialysis of the Clinical Centre of Vojvodina date back to 1973. Until 1992, the patients were subjected to this program only sporadically. Since 1998 the peritoneal dialysis method has been performed at the Clinic for Nephrology and Clinical Immunology. In the period 1998-2008 ninety nine peritoneal catheters were placed. Chronic glomerulonephritis, nephroangiosclerosis and diabetes were identified as the most common causes of chronic renal failure. Two methods of catheter placement were applied: the standard open surgery method (majority of patients) and laparoscopy. Most of the patients were subjected to continuous ambulatory peritoneal dialysis, whereas four patients received automatic dialysis. Transplantation was performed in 10 patients, i.e. cadaveric transplantation and living-related donor transplantation, each in 5 patients. Peritoneal dialysis was available as a service outside our institution as well. A ten-year experience in peritoneal dialysis gained at our Centre has proved the advantages and qualities of this method, strongly supporting its wider application in the treatment of terminal-stage chronic kidney failure.
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Kowalewska, Paulina M., Peter J. Margetts, and Alison E. Fox-Robichaud. "Peritoneal Dialysis Catheter Increases Leukocyte Recruitment in the Mouse Parietal Peritoneum Microcirculation and Causes Fibrosis." Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis 36, no. 1 (January 2016): 7–15. http://dx.doi.org/10.3747/pdi.2014.00211.

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♦BackgroundThe objective of this study was to examine the effects of a conventional dialysis solution and peritoneal catheter on leukocyte- endothelial cell interactions in the microcirculation of the parietal peritoneum in a subacute peritoneal dialysis (PD) mouse model.♦MethodsAn intraperitoneal (IP) catheter with a subcutaneous injection port was implanted into mice and, after a 2-week healing period, the animals were injected daily for 6 weeks with a 2.5% dextrose solution. Intravital microscopy (IVM) of the parietal peritoneum microcirculation was performed 4 hours after the last injection of the dialysis solution. Leukocyte-endothelial cell interactions were quantified and compared with catheterized controls without dialysis treatment and naïve mice.♦ ResultsThe number of rolling and extravascular leukocytes along with peritoneal fibrosis and neovascularization were significantly increased in the catheterized animals compared with naïve mice but did not significantly differ between the 2 groups of catheterized animals with sham injections or dialysis solution treatment.♦ConclusionThe peritoneal catheter implant increased leukocyte rolling and extravasation, peritoneal fibrosis and vascularization in the parietal peritoneum independently from the dialysis solution treatment.
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Hirahara, Ichiro, Eiji Kusano, Satoru Yanagiba, Yukio Miyata, Yasuhiro Ando, Shigeaki Muto, and Yasushi Asano. "Peritoneal Injury by Methylglyoxal in Peritoneal Dialysis." Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis 26, no. 3 (May 2006): 380–92. http://dx.doi.org/10.1177/089686080602600317.

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Background Peritoneal dialysis (PD) is a common treatment for patients with reduced or absent renal function. Long-term PD leads to peritoneal injury with structural changes and functional decline, such as ultrafiltration loss. At worst, peritoneal injury leads to encapsulating peritoneal sclerosis, a serious complication of PD. Glucose degradation products contained in PD fluids contribute to the bioincompatibility of conventional PD fluids. Methylglyoxal (MGO) is an extremely toxic glucose degradation product. The present study examined the injurious effect of MGO on peritoneum in vivo. Methods Male Sprague–Dawley rats ( n = 6) were administered PD fluids (pH 5.0) containing 0, 0.66, 2, 6.6, or 20 mmol/L MGO every day for 21 days. On day 22, peritoneal function was estimated by the peritoneal equilibration test. Drained dialysate was analyzed for type IV collagen-7S, matrix metalloproteinase (MMP), and vascular endothelial growth factor (VEGF). Histological analysis was also performed. Results In rats receiving PD fluids containing more than 0.66 mmol/L MGO, peritoneal function decreased significantly and levels of type IV collagen-7S and MMP-2 in drained dialysate increased significantly. In the 20-mmol/L MGO-treated rats, loss of body weight, expression of VEGF, thickening of the peritoneum, and formation of abdominal cocoon were induced. MMP-2 and VEGF were produced by infiltrating cells in the peritoneum. Type IV collagen was detected in basement membrane of microvessels. Conclusion MGO induced not only peritoneal injury but also abdominal cocoon formation in vivo. The decline of peritoneal function may result from reconstitution of microvessel basement membrane or neovascularization.
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Dissertations / Theses on the topic "Peritoneal dialysis"

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Vélez, Segovia E., Huayna Lourdes Salazar, and Bravo E. Alva. "Peritoneal dialysis in Peru." Indian Society of Nephrology, 2014. http://hdl.handle.net/10757/316272.

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Rodrigues, Anabela Soares. "Peritoneal membrane fast transport status in peritoneal dialysis." Doctoral thesis, Instituto de Ciências Biomédicas Abel Salazar, 2007. http://hdl.handle.net/10216/7153.

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Rodrigues, Anabela Soares. "Peritoneal membrane fast transport status in peritoneal dialysis." Tese, Instituto de Ciências Biomédicas Abel Salazar, 2007. http://hdl.handle.net/10216/7153.

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Lewis, Robert John. "Peritoneal defences in patients maintained on continuous ambulatory peritoneal dialysis : an investigation of macrophage phagocytosis within the dialysed peritoneum." Thesis, Imperial College London, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.243814.

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Campbell, Denise. "Peritoneal dialysis-related infections in patients on peritoneal dialysis and measures designed to prevent them." Thesis, The University of Sydney, 2016. http://hdl.handle.net/2123/16313.

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Individuals with end-stage kidney disease have the treatment options of receiving conservative care, dialysis or a kidney transplant. There are two main types of dialysis – haemodialysis and peritoneal dialysis. For a peritoneal dialysis (PD) program to be successful, close attention must be paid to preventing PD-related infections. A common and serious complication of PD is peritonitis. Peritonitis is a contributing cause of death in about 16% of PD patients and is a major cause of PD technique failure, which results in patients having to switch to long-term haemodialysis. The peritonitis rates of different renal centres are known to vary widely both within and between countries. Explanations for this variation are likely related to patient selection, patient training and infection-prevention protocols. This is a thesis by publication containing published and submitted work related to identifying barriers in practice to the uptake of relevant guideline recommendations, identifying current antimicrobial prophylaxis practice patterns in Australian and New Zealand (ANZ) PD units, assessing the evidence base for the antimicrobial agents used to prevent PD-related infections, and exploring patient experiences and beliefs about peritonitis. Chapter one is a general introduction to the topic. Chapter two is a narrative review of the literature relating to the prevention of PD-related infections. Chapter three is an original baseline study which assesses current practice and barriers to antimicrobial prophylaxis at 8 PD units. Chapter four is a systematic review of trials which have used various antimicrobial agents to prevent peritonitis in PD patients. Chapter five is an original survey study which assesses current antimicrobial prophylaxis practice at ANZ PD units. Chapter six is an original qualitative study that explores patients’ needs, experiences and beliefs about the prevention and treatment of peritonitis. The main aim of this thesis was to assess the current evidence base for the antimicrobial agents used, to establish current antimicrobial prophylaxis practice in ANZ PD units, to identify barriers to the uptake of guideline recommendations, and to explore patient experiences and beliefs about peritonitis and use the findings to suggest ways to improve the care and support they receive.
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Chen, Xiaorui. "Effects of high glucose, peritoneal dialysis fluid and heparin on proteoglycan synthesis in human peritoneal mesothelial cell /." Hong Kong : University of Hong Kong, 2001. http://sunzi.lib.hku.hk/hkuto/record.jsp?B23457387.

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Manera, Karine. "Standardised Outcomes in Nephrology – Peritoneal Dialysis (SONG-PD): establishing a core outcome set in peritoneal dialysis." Thesis, University of Sydney, 2020. https://hdl.handle.net/2123/23662.

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Worldwide, approximately 11% of patients on dialysis receive peritoneal dialysis (PD). Whilst PD may offer more autonomy to patients compared with hemodialysis, patient and caregiver burnout, technique failure, and peritonitis remain major challenges to the success of PD. Improvements in care and outcomes are likely to be mediated by randomised trials of innovative therapies, but will be limited if the outcomes measured and reported are not important for patients and clinicians. The aim of the Standardised Outcomes in Nephrology-Peritoneal Dialysis (SONG-PD) study is to establish a set of core outcomes for trials in patients receiving PD based on the shared priorities of all stakeholders, so that outcomes of most relevance for decision-making can be evaluated, and that interventions can be compared reliably. The phases of the SONG-PD project included in this thesis are: a systematic review to identify outcomes and outcome measures that have been reported in randomised trials involving patients receiving PD; focus groups using nominal group technique with patients and caregivers to identify, rank and describe reasons for their choice of outcomes; a 3-round international Delphi survey involving a multi-stakeholder panel; and a consensus workshop to review and endorse the proposed set of core outcome domains for PD trials. The establishment of 3 to 5 high-priority core outcomes, to be measured and reported consistently in all trials in PD, will enable patients and clinicians to make informed decisions about treatment based on outcomes of common importance.
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Rodriguez, Marvin O. "Automated peritoneal dialysis (APD) machine modeling." Thesis, California State University, Long Beach, 2017. http://pqdtopen.proquest.com/#viewpdf?dispub=10196401.

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A peritoneal dialysis cycler model was developed to be used by biomedical device manufacturers in order to aid them in the system development, system level requirement writing, and FDA device certification process. This generic model can be used as a plug and play model for companies to incorporate a specific dialysis pump that is commercially available and quickly integrate it into their system. The Simulink model was used to simulate the system behavior and analyze multi domain dynamic systems data. A mathematical representation of the physical system was derived using fluid dynamic equations. The mathematical equations were then translated into Simulink blocks for the computer environment to understand. A proportional integral derivative controller was designed and integrated into the system in order to compensate the flow rate for any difference between the flow set point and the actual flow. System monitors were developed to protect patients from hazardous conditions.

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陳曉瑞 and Xiaorui Chen. "Effects of high glucose, peritoneal dialysis fluid and heparin on proteoglycan synthesis in human peritoneal mesothelial cell." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2001. http://hub.hku.hk/bib/B31242960.

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Beduschi, Gabriela de Carvalho [UNESP]. "Diálise peritoneal ambulatorial contínua versus diálise peritoneal automatizada: análise dos dados do estudo multicêntrico brasileiro de diálise peritoneal (Braz-PD)." Universidade Estadual Paulista (UNESP), 2017. http://hdl.handle.net/11449/150379.

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Introdução: A terapia renal substitutiva por diálise peritoneal (DP) na doença renal crônica pode ser realizada manualmente pela DP ambulatorial contínua (CAPD) ou pala utilização de cicladoras automatizadas (APD). O impacto da modalidade de DP nos resultados clínicos, sobrevida do paciente, da técnica de diálise e risco de peritonite não foi avaliado por ensaios clínicos randomizados com alto número de pacientes. Estudos observacionais não mostraram de modo consistente, superioridade de um desses métodos. Objetivos: Comparar os resultados e desfechos clínicos do tratamento por CAPD e APD, em coorte de pacientes incidentes adultos e incluídos no Estudo Multicêntrico Brasileiro de Diálise Peritoneal (BRAZ-PD). Métodos: Estudo nacional de coorte prospectivo multicêntrico no qual foi incluídos pacientes incidentes com pelo menos 90 dias em DP. Os pacientes foram alocados em dois grupos, tratados exclusivamente por CAPD ou APD, utilizando-se o escore de propensão para pareamento dos mesmos, de acordo com as variáveis: idade, etnia, sexo, diabetes mellitus, índice de massa corporal, experiência do centro, biênio de início da DP, doença arterial coronária, doença arterial periférica, hipertensão arterial, presença de neoplasia maligna, tempo de escolaridade, renda familiar, tempo de acompanhamento pré-diálise e hemodiálise prévia. Os desfechos clínicos foram avaliados utilizando o modelo de risco proporcional de Cox e análise para riscos competitivos de Fine e Gray. A evolução dos dados bioquímicos, hemoglobina e pressão arterial foi comparada pelo teste t ou teste de Wilcoxon. Resultados: Após o pareamento, 1445 pacientes incidentes foram incluídos em cada grupo. O risco de morte por todas as causas (SHR1.44 CI95%1.21-1.71) e por causa cardiovascular (SHR1.34 CI95%1.03-1.73) foi maior nos pacientes em CAPD, mas não observamos diferença na sobrevida da técnica e tempo para o primeiro episódio de peritonite. As médias de concentração sérica de potássio e de fósforo foram menores nos pacientes em CAPD na maioria das avalições, não se observando diferenças no controle pressórico e das demais variáveis. Conclusão: Com base em um grande estudo de coorte, randomizado e prospectivo, não foram encontradas diferenças na falência da técnica e tempo para o primeiro episódio de peritonite entre a CAPD e APD. Por outro lado, a APD se associou a maior sobrevida do paciente em comparação com CAPD. Esses achados podem influenciar a escolha da modalidade e estimular uma mais ampla utilização da APD.
Introduction: Renal substitutive therapy by peritoneal dialysis (PD) in chronic kidney disease patients can be performed manually by continuous ambulatory PD (CAPD) or using automated cyclers (APD).The impact of PD modality on patient survival, technique failure and peritonitis rates is not fully understood, and no large-scale randomized clinical trial is available. Observational studies have failed to show superiority of one of PD modalities. Objective: The aim of this study is to compare the clinical results and endpoints between CAPD and APD, in a large nation-wide PD cohort, BRAZ-PD. Methods: This is a prospective cohort study that included all incident PD patients with at least 90 days of PD recruited in the BRAZ-PD study. All patients who were treated exclusively with either CAPD or APD were matched for different covariates (age, diabetes, BMI, center-experience, coronary artery disease, cancer, literacy, hypertension, race, previous hemodialysis, gender, pre-dialysis care, family income, peripheral artery disease and year of starting PD) using a propensity score calculated with the nearest neighbor method. Clinical outcomes analyzed were overall mortality, technique failure and time to first peritonitis. For all analysis we also adjusted the curves for the presence of competing risks with the Fine and Gray analysis. Biochemical data, blood pressure and hemoglobin levels were compared by test or Wilcoxon test. Results: After the matching procedure, 1,445 patients were included in each group. General (SHR1.44 CI95%1.21-1.71) and cardiovascular mortality risk (SHR1.34 CI95%1.03-1.73) were higher in CAPD patients, but no difference was observed for technique failure nor for time till the first peritonitis episode. The mean of serum and phosphorus concentration were lower in CAPD group in the majority of measurements. Conclusion: In the first large PD cohort study with groups balanced for several covariates using propensity score matching, PD modality was not associated with differences in neither time to first peritonitis nor in technique failure. Nevertheless, patient survival was significantly better in APD patients. These findings can influence the PD modality choice and encourage a greater APD utilization.
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Books on the topic "Peritoneal dialysis"

1

Nolph, Karl D., ed. Peritoneal dialysis. Dordrecht: Springer Netherlands, 1985. http://dx.doi.org/10.1007/978-94-017-2560-6.

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Nolph, Karl D., ed. Peritoneal Dialysis. Dordrecht: Springer Netherlands, 1989. http://dx.doi.org/10.1007/978-94-009-1085-0.

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D, Nolph Karl, ed. Peritoneal dialysis. 2nd ed. Boston: Nijhoff, 1985.

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D, Nolph Karl, ed. Peritoneal dialysis. 3rd ed. Dordrecht: Kluwer Academic Publishers, 1989.

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Rastogi, Anjay, Edgar V. Lerma, and Joanne M. Bargman, eds. Applied Peritoneal Dialysis. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-030-70897-9.

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Avram, Morrell M., Carmelo Giordano, Natale G. DeSanto, Neal Mittman, Giorgio Bazzato, Paul A. Fein, Amado Gan, Philip Goldwasser, and Paul A. Slater, eds. Ambulatory Peritoneal Dialysis. Boston, MA: Springer US, 1990. http://dx.doi.org/10.1007/978-1-4615-9555-7.

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1951-, Ronco C., Dell'Aquila Roberto, and Rodighiero Maria Pia, eds. Peritoneal dialysis today. Basel: Karger, 2003.

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1929-, Avram Morrell M., Giordano Carmelo, and International Congress of Peritoneal Dialysis, eds. Ambulatory peritoneal dialysis. New York: Plenum Medical Book Co., 1990.

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Gokal, R., R. Khanna, R. Th Krediet, and K. D. Nolph, eds. Textbook of Peritoneal Dialysis. Dordrecht: Springer Netherlands, 2000. http://dx.doi.org/10.1007/978-94-017-3225-3.

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Coles, G. A. Manual of Peritoneal Dialysis. Dordrecht: Springer Netherlands, 1988. http://dx.doi.org/10.1007/978-94-009-2621-9.

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Book chapters on the topic "Peritoneal dialysis"

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Reddi, Alluru S. "Peritoneal Dialysis." In Absolute Nephrology Review, 399–419. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-22948-5_10.

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Patel, Chhaya, and Jerrilynn D. Burrowes. "Peritoneal Dialysis." In Nutrition in Kidney Disease, 283–99. Cham: Springer International Publishing, 2020. http://dx.doi.org/10.1007/978-3-030-44858-5_16.

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Verrina, Enrico. "Peritoneal Dialysis." In Pediatric Nephrology, 1785–816. Berlin, Heidelberg: Springer Berlin Heidelberg, 2009. http://dx.doi.org/10.1007/978-3-540-76341-3_72.

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Findlay, Mark, and Christopher Isles. "Peritoneal Dialysis." In Clinical Companion in Nephrology, 199–204. Cham: Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-14868-7_38.

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Labato, Mary Anna. "Peritoneal Dialysis." In Nephrology and Urology of Small Animals, 293–305. West Sussex, UK: John Wiley & Sons, Ltd., 2014. http://dx.doi.org/10.1002/9781118785546.ch30.

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Skarda, David E. "Peritoneal Dialysis." In Fundamentals of Pediatric Surgery, 605–10. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-27443-0_74.

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Kray, Jared, and W. Kirt Nichols. "Peritoneal Dialysis." In Hemodialysis Access, 333–43. Cham: Springer International Publishing, 2016. http://dx.doi.org/10.1007/978-3-319-40061-7_40.

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Mees, Evert J. Dorhout. "Peritoneal dialysis." In Cardiovascular Aspects of Dialysis Treatment, 122–30. Dordrecht: Springer Netherlands, 2000. http://dx.doi.org/10.1007/978-94-017-0973-6_13.

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Smith, Sue. "Peritoneal Dialysis." In Skills Update, 8–9. London: Macmillan Education UK, 1994. http://dx.doi.org/10.1007/978-1-349-13584-4_4.

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Little, Danny, and Monford D. Custer. "Peritoneal Dialysis." In Fundamentals of Pediatric Surgery, 553–57. New York, NY: Springer New York, 2010. http://dx.doi.org/10.1007/978-1-4419-6643-8_71.

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Conference papers on the topic "Peritoneal dialysis"

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Tsai, Wen-Chung, Tsung-Sheng Hsu, Yu-Huei Cheng, and Huan-Hsiuan Lin. "Intelligent Household Peritoneal Dialysis System." In 2023 12th International Conference on Awareness Science and Technology (iCAST). IEEE, 2023. http://dx.doi.org/10.1109/icast57874.2023.10359314.

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Zunino, Paolo, and Diego Mastalli. "Optimal control of peritoneal dialysis." In Control Systems: Theory, Numerics and Applications. Trieste, Italy: Sissa Medialab, 2006. http://dx.doi.org/10.22323/1.018.0018.

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Putrya, Boris M., Nikita M. Zhilo, and Nikolay A. Bazaev. "Peritoneal Dialysis Simulation Set-up." In 2022 Conference of Russian Young Researchers in Electrical and Electronic Engineering (ElConRus). IEEE, 2022. http://dx.doi.org/10.1109/elconrus54750.2022.9755620.

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Udit, C., S. Arjun, H. Mashaal, and F. Anjum. "Sweet Hydrothorax - A Rare Complication of Peritoneal Dialysis." In American Thoracic Society 2021 International Conference, May 14-19, 2021 - San Diego, CA. American Thoracic Society, 2021. http://dx.doi.org/10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a1960.

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Zhu, Fansan, Laura Rosales M., Lela Tisdale, Maricar Villarama, and Peter Kotanko. "Measurement of peritoneal fluid absorption and ultrafiltration during peritoneal dialysis using segmental bioimpedance." In 2022 44th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC). IEEE, 2022. http://dx.doi.org/10.1109/embc48229.2022.9870833.

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Putrya, Boris M., Nikita M. Zhilo, Victor M. Grinvalrd, and Nikolay A. Bazaev. "Detection of P-Cresol in Solution for Peritoneal Dialysis." In 2019 IEEE Conference of Russian Young Researchers in Electrical and Electronic Engineering (EIConRus). IEEE, 2019. http://dx.doi.org/10.1109/eiconrus.2019.8657038.

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Argento, A. C., Behrouz Jafari, Melissa Knauert, Mark D. Siegel, Anthony W. Kim, and Jonathan T. Puchalski. "Tension Hydrothorax Secondary To Pleuroperitoneal Leak Related To Peritoneal Dialysis." In American Thoracic Society 2010 International Conference, May 14-19, 2010 • New Orleans. American Thoracic Society, 2010. http://dx.doi.org/10.1164/ajrccm-conference.2010.181.1_meetingabstracts.a1480.

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Shu, Chin-Chung, Feng-Jung Yang, Vincet Wu, Jann-Yuan Wang, and Li-Na Lee. "Surveillance Of Latent Tuberculosis Infection In Long-Term Dialysis Patients: Comparing Mode Of Hemodialysis And Peritoneal Dialysis." In American Thoracic Society 2012 International Conference, May 18-23, 2012 • San Francisco, California. American Thoracic Society, 2012. http://dx.doi.org/10.1164/ajrccm-conference.2012.185.1_meetingabstracts.a3323.

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Ghobrial Morgos, Rafaa Ashamallah, and Khalid Mohamemd Alhassan Alakad. "Perception of Sudan Peritoneal Dialysis Program's staff to medical electronic records." In 2014 IST-Africa Conference & Exhibition. IEEE, 2014. http://dx.doi.org/10.1109/istafrica.2014.6880637.

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Supraja, K., G. Abraham, and A. Jayanthi. "Effect of Peritoneal Dialysis on the Dynamic Functions of the Diaphragm." In American Thoracic Society 2019 International Conference, May 17-22, 2019 - Dallas, TX. American Thoracic Society, 2019. http://dx.doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a5787.

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Reports on the topic "Peritoneal dialysis"

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Subramanian, Lalita, Junhui Zhao, Jarcy Jarcy Zee, and Francesca Tentori. Selection of Peritoneal Dialysis or Hemodialysis for Kidney Failure: Gaining Meaningful Information for Patients and Caregivers. Patient-Centered Outcomes Research Institute (PCORI), October 2018. http://dx.doi.org/10.25302/10.2018.cer.1109.

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Ji, LinMei, Wansheng Zhu, Yu Liu, Kejun Xiao, Qiongdan Zhang, Changlian Li, and Guang Zeng. Roxadustat (FG-4592) treatment for anemia in peritoneal dialysis-dependent (PDD) chronic kidney disease patients: A systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, June 2021. http://dx.doi.org/10.37766/inplasy2021.6.0053.

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Xue, Xue, Chun-li Lu, Xin-yan Jin, Xue-han Liu, Min Yang, Xiao-qin Wang, Hong Cheng, et al. Association of serum uric acid with all-cause and cardiovascular mortality in peritoneal dialysis patients: a systematic review and meta-analysis of observational studies. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, April 2021. http://dx.doi.org/10.37766/inplasy2021.4.0020.

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Thomson, Scott. A prospective, randomised controlled trial to determine the safety and efficacy of steroid impregnated tape compared to standard therapy with silver nitrate in the treatment of over-granulating peritoneal dialysis catheter exit sites. National Institute for Health and Care Research (NIHR), March 2022. http://dx.doi.org/10.3310/nihropenres.1115184.1.

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Kidney failure: medical insertion of catheters for peritoneal dialysis is as safe as surgery. National Institute for Health Research, April 2024. http://dx.doi.org/10.3310/nihrevidence_62664.

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