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Dissertations / Theses on the topic 'Periphery'
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Jarrett, Lisa Nicole. "Past periphery." Diss., [Missoula, Mont.] : The University of Montana, 2009. http://etd.lib.umt.edu/theses/available/etd-06222009-182501.
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Ozdemir, Esin. "Different Definitions Of." Master's thesis, METU, 2005. http://etd.lib.metu.edu.tr/upload/12606217/index.pdf.
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The definition of the periphery can be made in in different ways, based on the concepts emphisized in different theoretical discussions. Correspondingly, different peripheries appear in Europe from the perspectives of these different definitions. The thesis puts forward five different definitions of the peripherydefinition of the periphery based on income and income growth differentials
definition of the periphery by using economic structure, employment and population potentials
definition of the periphery based on welfare conditions
definition of the periphery based on externalities
and definition of the periphery based on endogenous growth dynamics. All these definitions produce different core-periphery maps of Europe. The evidence is based on the use of cluster analysis to identify different groups of regions homogenous in terms of variables that belong to every one of these five definitions. The result confirms that there are different peripheries in Europe. One region that is categorised as core can fall into a peripheral group in a different clasification. This shows that there is not only one type of periphery in Europe, but that different peripheries appear in case of the usage of different variables. The thesis also argues that there is a need for regional policies that do not the define the periphery as a homogenous area by considering only income differentials, but that identifies different peripheries that have different needs and problems, and devise instruments accordingly.
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Thrond, Matthew Dale. "Center of the periphery." Thesis, [Austin, Tex. : University of Texas Libraries, 2009. http://hdl.handle.net/2152/ETD-UT-2009-05-165.
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Sweitz, Samuel Randles. "On the periphery of the periphery: household archaeology at Hacienda Tabi, Yucatan, Mexico." Texas A&M University, 2005. http://hdl.handle.net/1969.1/4356.
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The archaeological remains at Hacienda Tabi provide an opportunity to study the
effects of large-scale societal changes on the lives of the Maya who worked on the
hacienda. The households, represented by the ruins of the workerâÂÂs village surrounding
the main hacienda grounds, were at the core of late colonial/independence era Maya life.
These households were subject to the forces of acculturation that accompanied the rise
and supremacy of the hacienda system during the late eighteenth century.
Archaeological excavations at Hacienda Tabi have revealed a re-orientation of
social organization during this period. Prior to the formation of the hacienda system,
domestic and social organization focused on kinship and extended family subsistence
organization. Social status, wealth, and power in pre-hacienda communities were
predicated on issues of age, sex, and familial rank within both the extended family and
community. The hacienda system brought about fundamental changes in the
organization and relations of production. These changes, e.g. the separation of producer
from the means of production and commodity based production versus subsistence based
production, changed the basis and therefore the form of Yucatecan social organization. Under the new system, the nuclear family rather than the extended family or community
became the prime unit of social organization. In the hacienda community status was
based on occupation and oneâÂÂs place within the newly established labor hierarchy.
The changing realities of social organization found under the hacienda system are
reflected in the settlement patterns and material remains of the workersâ village at
Hacienda Tabi. The material culture and types of housing excavated and recorded at
Tabi underscore the inequalities engendered within the hacienda system of production.
The research conducted at Hacienda Tabi has illuminated the changes associated with
YucatanâÂÂs articulation into the greater world system.
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MacCaluim, Alasdair. "Periphery of the periphery? : adult learners of Scottish Gaelic and reversal of language shift." Thesis, University of Edinburgh, 2002. http://hdl.handle.net/1842/18383.
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Due to the advanced state which Gaelic-English language shift has reached in Scotland, Gaelic learners are now increasingly recognised as having a central role in reversing this process. The present detailed study of adult learners of Scottish Gaelic was undertaken in order to provide an overview of the contemporary world of the Gaelic learner with particular reference to reversing language shift [RLS]. The infrastructure for Gaelic learning is investigated in detail. It is shown that the present facilities for learning the language and for attracting learners tend to be limited, ad-hoc, fragmented and uncoordinated with several significant gaps in provision and with no overall framework or strategic direction. The weaknesses of the Gaelic learning infrastructure have been reflected in the fact that very few Gaelic learners reach fluency. The social identity of the Gaelic learner is investigated next, looking at the position of the learner within the Gaelic speech community and linking this to the question of RLS. It is argued that the learner occupies a somewhat ambiguous social standing within this community, creating both advantages and disadvantages for the individual learner, but offering many advantages from the point of view of RLS. A large scale questionnaire survey of Gaelic learners was undertaken as part of the study, investigating the social background and motivation of learners, their attitudes towards their language and their impact on regenerating the language. In addition to supporting the arguments made both with regard to the Gaelic learning infrastructure and social identity of learners, it can be shown that learners bring many positive benefits to RLS efforts, including enthusiasm, knowledge of Gaelic issues, pro-Gaelic views, strong motivations for learning, and the provision of a market for Gaelic related goods and services. However, the potential for learners at act as significant force in RLS is not currently being fulfilled due to high average age of learners and the failure of a large majority to reach fluency.
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Le, Tuan Anh (Andrew). "Community-based Tourism and Development in the Periphery/Semi-periphery Interface of Viet Nam." Thesis, Griffith University, 2014. http://hdl.handle.net/10072/366327.
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Community-based tourism (CBT) is widely accepted as an effective facilitator of sustainable development that reduces exploitation and brings about benefits for local communities in the least developed and remote areas. However, whilst CBT can be a catalyst for local income and employment generation, its contribution to improving local development is often overestimated and inaccurately identified. This is in part because development and its measurement are mainly assessed by non-locals who do not adequately take into account the opinions of residents. There is increasing concern that most of the impetus and funding for CBT, and its ongoing product viability, is attributable to Western “experts” and development agencies, and that far too little attention has been paid to local perspectives, empowerment, and knowledge. With regard to a CBT context, there is presently no study that adequately explores the local community’s perception of “development”; how CBT contributes to achieving that development; what factors facilitate or inhibit CBT to this effect; and how CBT can be improved so that it serves more effectively to promote development.
Additionally, most studies focus on destinations in the classic periphery and neglect the fact that many CBT projects are found in the dynamic interface between the periphery and the rapidly expanding semi-periphery regions that represent the frontier of contemporary economic development in emerging economies such as Viet Nam. Importantly, this interface functions as a gateway to large tourist numbers, indicating a potential relationship between CBT – traditionally considered a manifestation of alternative tourism – and mass tourism.Thesis (PhD Doctorate)
Doctor of Philosophy (PhD)
Griffith Business School
Griffith Business School
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Villalba, Xavier 1969. "The syntax of sentence periphery." Doctoral thesis, Universitat Autònoma de Barcelona, 2000. http://hdl.handle.net/10803/4838.
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Martinez, Perez A. "The architecture of the periphery." Thesis, University of Sheffield, 2016. http://etheses.whiterose.ac.uk/15482/.
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Aldo Rossi’s L’archittetura della citta (The Architecture of the City) has proven to be one of the most influential architecture manifestoes of the 20th century. Written against the backdrop of the CIAM and Functionalism it offered a theory of the elements that constitute the architecture of the city. Rafael Moneo writes: “As a critic no one can question the insightful value of Rossi’s oeuvre. From the knowledge of the ancient city it has been possible to make a critique of modern urbanism that has shown its terrible gaps and, therefore, the role that the ancient city has played as an antidote to that has been of prime importance. This has been his most important contribution to the development of current urban thinking.” The last chapter of Rossi’s book emphasizes the importance of investigating the peripheries of the European city, and offers a starting point for this thesis. Moreover, according to Rossi there is a clear relationship between architectural theory and the project, and this thesis explores this assertion in the context of the city of Madrid. No other European city has undergone a similar scale of development in recent years regarding peripheral and infrastructural development. Picking up from Rossi’s final chapter, this thesis asks whether it is possible to establish a theory of the architecture of the periphery of the European city. To arrive at such a theory, Rossi’s methodology, developed for his reading of the traditional city, needs to be supplemented and developed. Here, this work will be started by drawing on the contribution of Rossi’s contemporaries Robert Venturi and Denise Scott-Brown (Learning from Las Vegas ). The gaps left in the theory also requires new approaches for the methodology and its application, and fieldwork techniques are used here that embrace other forms of exploring these territories, including walking and visual tools such as photography, in order to map, and to analyse and understand, these environments. This PhD uses fieldwork to look at different areas developed to the North and South of Madrid, in combination with architectural theory, in order to describe, analyse and understand the architecture of the periphery, and to define the gaps between architectural theory and project. In addition to this understanding of the architecture of the periphery, the thesis also makes a methodological contribution, developing practical and analytical tools and building a theory that offers new ways of analysing other European peripheries.
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Nheu, Anie Art College of Fine Arts UNSW. "At the periphery of space." Awarded by:University of New South Wales. Art, 2008. http://handle.unsw.edu.au/1959.4/43554.
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MacAlpine, Jill. "Chemistry at the porphyrin periphery." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1999. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape7/PQDD_0018/NQ46380.pdf.
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Tannahill, Lisa. "Bande dessinée on the periphery." Thesis, University of Glasgow, 2016. http://theses.gla.ac.uk/7599/.
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This thesis examines how Brittany and Corsica are represented in the medium of bande dessinée. Both are peripheral French regions with cultural identities markedly different from that of the overarching French norm, and both have been historically subject to ridicule from the political and cultural centre. By comparing a fair selection of bandes dessinées which are either set in Brittany or Corsica or feature characters from the relevant regions, this thesis sets out to discover whether representations of Brittany and Corsica differ according to the origin of the creators of the bandes dessinées and, if so, how. To facilitate this analysis, the bandes dessinées included for study have been classified as either external representations (published by mainstream bande dessinée publishers and/or the work of creators originating from outside the two regions) or internal representations (published by local Breton or Corsican companies and/or the work of local creators). It transpires that there are clear differences between mainstream and local bande dessinée authors and illustrators with regard to their portrayal of the local culture of both ‘outlying’ regions. External representations rely on broad stereotypes and received ideas, while internal representations draw on local folklore, regional history and regional identity to create works with more local relevance. In some cases internal representations are or were clearly aimed at a local market, while others aim both at local readers and at the wider bande dessinée market. Those aimed at a wider readership have an additional function, namely that of promoting their regional cultures in French culture generally and offering an alternative to the stereotypical representations presented by larger publishers of bandes dessinées. Brittany and Corsica are examined separately, each taking up roughly half of the thesis. Each half has the same general structure, beginning with discussion of how historical events have shaped perceptions of Brittany and Corsica in French popular consciousness, followed by analysis of the respective external representations and lastly internal representations. There are also two case studies of representations of Corsica in wider visual culture. Owing to its widespread appeal, its adaptability and its capacity to reflect popular opinion in different sectors of society, the medium of bande dessinée offers a potentially rich field for the investigation of social and cultural attitudes and prejudices. It is hoped that this thesis points the way to further research on the topic.
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Arenari, Brand. "Pentecostalism as religion of periphery." Doctoral thesis, Humboldt-Universität zu Berlin, Philosophische Fakultät III, 2015. http://dx.doi.org/10.18452/17182.
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Alle in dieser Dissertation gemachten Analysen fokussieren auf einen zentralen Element für die Entstehung und die Entwicklung der Pfingstbewegung. Es handelt sich dabei um das Konzept, dass sich religiöse Erlösung auf die Erfahrung des sozialen Aufstiegs gegründet ist, insbesondere im Sinne der Integration unterintegrierter sozialen Gruppen in die Gesellschaft. Diese in den USA enstandende neue Religion befriegt vor allem die religiösen und sozialen Bedürfnisse derjenigen Bevolkerungsgruppen, die neu in der urbanen Welt der großen nordamerikanischen Städten angekommen waren. Es geht dabei also um diejenigen sozialen Schichten, die in der Peripherie dieser grossen Städte lebeten und die sozial, wirtschaftlichund ethnisch aus der Gesellschaft ausgeschlossen wurden. Im Anschluss daran analysieren wir auch, wie die gleichen sozialen und religiösen Bedürfnisse die Grundlagen für die Entwicklung der Pfingstbewegung in Lateinamerika darstellen – insbesondere in Brasilien. In diesem Land findet eine grosse Menge exkludierter Individuen, die meistens auch Bewohner städtischer Peripherie sind (was ihren modernen Charakter beweist), im Pentekostalismus das Versprechen einer Lösung für ihre Probleme, vor allem für die Sehensucht nach Integration in eine soziale Welt, an der sie vorher nicht teilnahmen. Dieses Integrationsversprechen hängt direkt mit der normativen Erwartung des sozialen Aufstiegs zusammen. Aus disem Bild kann man den Schluss ziehen, dass sich der Pentekostalismus als religiöses Phänomen dadurch auszeichnet, dass er die Versprechen der Moderne für die von der modernen Gesellschaften vergessenen Individuen aktualisiert. Mittes seiner religiösen Narrative verleiht der Petenkostalismus der Idee des sozialen Aufstiegs und damit auch der Hoffnung sozialer Inklusion exkludierter Individuen eine neue Kraft. Der Pentekostalismus nimmt auf diese Weise die Form einer christlichen Religion der Schwarzen, Mulatos, Armen und aller anderen Individuen an, deren Integration in die moderne Gesellschaft als problematisch erscheint.All the analyses we have developed throughout this dissertation point to a central element in the emergence and development of Pentecostalism, i.e., its raw material – the promise of religious salvation – is based on the idea of social ascension, particularly the ascension related to the integration of sub-integrated social groups to the dynamics of society. The new religion that arose in the USA focused on the needs and social dramas that were specific of the newly arrived to the urban world of the large North-American cities, those who inhabited the periphery of these cities, those that were socially, economically, and ethnically excluded from the core of society. We also analyzed how the same social drama was the basis for the development of Pentecostalism in Latin America and, especially, in Brazil. In this country, a great mass of excluded individuals, also residents of urban peripheries (which proves the non-traditional and modern characteristic of these sectors), found in Pentecostalism the promises of answers to their dramas, mainly the anxiety to become integrated to a world in which they did not belong before. Such integration was embedded in the promise present in the modernity of social ascension. This scenario leads us to the conclusion that Pentecostalism was a religious discourse capable of taking the main promise of modernity to social groups or classes “forgotten” by modern society. Through a religious discourse, Pentecostalism fulfilled the notions of social mobility, and its consequent idea of individual ascension to the mass of people not yet fully integrated to the modern world, but living in it. Following, it became the Christian religion of blacks and mestizos, of the poor and all the others who felt out of place in that world. So the Pentecostalism became a religion of periphery par excellence.
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Han, Shuhua. "β-lymphocyte differentiation in the periphery." Thesis, Imperial College London, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.326157.
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McBurnie, Ian. "The periphery and the American dream." Thesis, Open University, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.284359.
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McGrath, Christine L. (Christine Lynn). "Consolidated periphery : commercial and highway interchange." Thesis, Massachusetts Institute of Technology, 1997. http://hdl.handle.net/1721.1/68778.
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Thesis (M. Arch.)--Massachusetts Institute of Technology, Dept. of Architecture, 1997.Includes bibliographical references (p. 117-122).
Highway expansion legislation has been a significant catalyst for suburban development. Initially funded for military mobilization in the 1930s , later massively extended in the 1950s, today's highway system, together with the service and information based economy of postindustrial development, have allowed for the dispersion of traditionally urban functions into continuously less urbanized peripheries. As the ambiguous zone between city and country is inhabited, suburbia emerges. Commercial, industrial and residential development take hold at new highway interchanges, bringing to suburbia the functions and amenities of a city, yet in a manner completely unique to its own position. In suburbia the landscape consists of sprawling fields of independent, privately-held capsules. "Centers " and "edges" are trivialized, if even discernible. Nondescript "architecture" is governed by economic and marketing strategies, subsidizing the making of space to the making of corporate identity. While the highway system itself i s enabled through massive public investment, its "archi tecture" -- the strip -- is entirely private in its motivation. This thesis proposes that the rational of the suburban strip landscape can be challenged through the insertion of generic private development into public infrastructure. Through the design of a commercial strip within a highway interchange it obviates tensions inherent in the suburban condition. The thesis implicates archi tecture as both a physical and conceptual mediator; it is the material interface between highway and town, and the ideological interface between public space and private enterprise.
Christine L. McGrath.
M.Arch.
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Brathwaite, Darren David 1970. "Engaging the periphery : integrating port and city." Thesis, Massachusetts Institute of Technology, 1998. http://hdl.handle.net/1721.1/64903.
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Thesis (S.M.)--Massachusetts Institute of Technology, Dept. of Architecture, 1998.Includes bibliographical references (leaf 76).
The common urban waterfront is hardly approachable, much less swimmable, encrusted with wharves, switching yards, sewage out-jalls and other barnacles. It is the true civic outcast, the ghetto of ghettos, familiar only to longshoremen, sanitary engineers and carp. -- THE WATERFRONT. After World War II, a number of factors came together to affect the urban waterfront. Subsequently, these factors lead to the demise, and later the waterfront redevelopment phenomena of our time. In the 1940's, the United States led the world in a series of technological innovations in Port design and industry. Most pertinent to the urban waterfront was the introduction of the container system which revolutionized the shipping industry, much to the expense of the urban waterfront. Soon after its introduction, the container system became the benchmark system in Port technology rendering the traditional "break bulk" dock facilities obsolete. With this systemic change also came a set of infra structural requirements. Container ports require large, new spaces, plus more acreage for backup space as well as deeper and wider channels for the ships. In addition, they also require access to transportation and infrastructure, rendering the existing industrial warehouses and their waterfront rail networks useless. As a result, many urban waterfronts became deserted industrial compounds functioning neither as a viable port for industry nor as a waterfront to the city. At approximately the same time, America's entire pattern of settlement began to shift in the 1950's away from central cities to suburban sprawl. Consequently, vast amounts of urban waterfront land became available, relatively cheaply without dislocating current users. One of the first uses for these abandoned shoreline areas was to aid the burgeoning highway system. As the highway system took hold in the city's infrastructure, the city and the waterfront became alienated entities. Since the formation of the city as an inhabitable entity, the waterfront has played a key role in its development and its sustenance. Within the context of urban life the waterfront can become a pause or reconnection to serenity, vital to restoring a sense calm to the city's inhabitants. Modem waterfronts should become a "center" of sorts favoring public interests over industry and private enterprise. In this arena, the task of urban design is to provide the necessary interface between the city's core and its periphery therefore engaging the life of the city of the pulse of the people. With respect to this philosophy, this Thesis attempts to provide an interface between the city's core and its periphery.
by Darren David Brathwaite.
S.M.
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Gardner, Dustin J. "Investigation of Myopic Periphery Affecting Choroidal Thickness." The Ohio State University, 2013. http://rave.ohiolink.edu/etdc/view?acc_num=osu1366286421.
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López-Cortina, Jorge. "The Spanish left periphery questions and answers /." Connect to Electronic Thesis (ProQuest) Connect to Electronic Thesis (CONTENTdm), 2007. http://worldcat.org/oclc/436261554/viewonline.
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Zagaeski, Mark. "Information processing in the mammalian auditory periphery." Thesis, Boston University, 1991. https://hdl.handle.net/2144/37176.
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Thesis (Ph.D.)--Boston UniversityPLEASE NOTE: Boston University Libraries did not receive an Authorization To Manage form for this thesis or dissertation. It is therefore not openly accessible, though it may be available by request. If you are the author or principal advisor of this work and would like to request open access for it, please contact us at open-help@bu.edu. Thank you.
Inner hair cells (IHC) are the primary sensory cells of the mammalian cochlea. They transduce sound energy into a changing receptor potential which stimulates electrical activity in the Type I spiral ganglion cells of the auditory nerve. The auditory information thus encoded leads to the sensation of hearing. This thesis comprises my attempts to elucidate some of the biophysical mechanisms operating in the cochlea by analyzing intracellular recordings from guinea pigs, and to investigate the role these mechanisms play in auditory information processing via conceptual and computational models. Noise in the IHC receptor potential sets limits on the performance of a single cell. The magnitude of the intracellular noise averages 0.3 m V rms. A single IHC will be limited by this noise to: (i) a minimum detectable receptor potential of 0.3 mV (corresponding to about 0 dB SPL), (ii) a channel capacity of 5100 bits/sec, and (iii) a temporal resolution of 42 JLS. I compare these single cell limits to auditory performance as observed in published behavioral studies. The IHC receptor potential is shaped by at least two nonlinear processes: nonlinear transduction and a voltage dependent membrane conductance. I characterized the nonlinear conductance by analyzing recordings made during intracellular current injection. A simple model containing a two-state voltage-gated channel was sufficient to replicate the current-voltage characteristic found in these cells. I investigated the information transfer from inner hair cells to the auditory nerve by comparing the growth of the de receptor potential to the average firing rate in spiral ganglion cells. This comparison suggests that neural units with different thresholds encode different portions of the IHC dynamic range; at conditions well above threshold, low threshold units may be carrying predominantly temporal information while high threshold units may encode the absolute sound level. To help understand the complex behavior of the IHC receptor potential, I developed a computational model for its generation. The model contains gated ion channel descriptions of the nonlinear transducer and membrane conductance. Analysis of the model suggests a possible role for the voltage dependent conductance: efficiently trading sensitivity for temporal resolution as stimulus level increases.
2031-01-01
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Heffernan, Valerie. "Provocation from the periphery Robert Walser re-examined." Würzburg Königshausen und Neumann, 2004. http://deposit.d-nb.de/cgi-bin/dokserv?id=2883790&prov=M&dok_var=1&dok_ext=htm.
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Witz, Nirel. "Properties of global stereopsis in fovea and periphery." Thesis, McGill University, 2013. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=114281.
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To better understand the properties and mechanisms underlying global stereopsis we examined the relationship between carrier luminance spatial frequency and modulator disparity spatial frequency. Thresholds for detecting global sinusoidal disparity corrugations of equi-detectable spatially band-pass noise were measured as a function of modulator disparity spatial frequency for both centrally and peripherally located stimuli using a standard 2-IFC task. We found a characteristic relationship that depended on modulator disparity spatial frequency. At high modulator disparity spatial frequencies (>1 c/d), there is an optimum ratio of around 2.6, whereas at low modulator disparity spatial frequencies, there is an optimum absolute carrier luminance spatial frequency (i.e., 3 c/d). In the periphery, vision is restricted to modulator disparity spatial frequencies below 1 c/d and, as a consequence, follows the latter rule with the optimum carrier luminance spatial frequency reducing with increasing eccentricity. This finding is consistent with there being more than one channel processing global stereo. This was confirmed using a 2x2 AFC detection/discrimination paradigm. Furthermore, because of the different carrier/modulator relationships in central and peripheral vision, peripheral global stereo cannot be simply related to central global stereo by a scaling factor and thus cannot be simply due to cortical magnification as has been suggested.Afin de mieux comprendre les propriétés et les mécanismes sous-tendant la stéréoscopie, nous avons examiné la relation entre la fréquence spatiale de luminance de la porteuse et la fréquence spatiale de disparité de l'enveloppe. Les seuils de détection d'une ondulation sinusoïdale de disparité portée par un bruit passe-bande équi-détectable ont été mesurés en fonction de la fréquence spatiale de disparité de l'enveloppe à la fois pour des stimuli centraux et périphériques en utilisant une tâche standard de choix forcé entre 2 intervalles. Nous avons trouvé une relation caractéristique qui dépend de la fréquence spatiale de disparité de l'enveloppe. À hautes-fréquences spatiales de disparité de l'enveloppe (>1 c/d), le rapport optimal est d'environ 2.6, alors qu'à basses-fréquences spatiales de disparité de l'enveloppe, la fréquence spatiale de luminance absolue de la porteuse présente un optimum (i.e., 3 c/d). En périphérie, la vision est restreinte aux fréquences spatiales de disparité de l'enveloppe inférieures à 1 c/d. En conséquence, suivant cette dernière règle, la fréquence spatiale de luminance optimale de la porteuse diminue avec l'excentricité. Cette observation est cohérente avec la présence de plusieurs canaux de traitement de la stéréoscopie globale et se confirme en utilisant un paradigme de 2x2 choix forcés détection/discrimination. De plus, en raison des différentes relations entre porteuse et enveloppe en vision centrale et périphérique, la stéréoscopie globale périphérique ne peut pas être simplement liée à la stéréoscopie globale centrale par un facteur d'échelle et ne peut ainsi pas être simplement due à la magnification corticale comme il a été suggéré.
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Maekawa, Takafumi. "The English left periphery in linearisation-based HPSG." Thesis, University of Essex, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.435586.
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Lingford-Hughes, A. "Cholecystokinin receptor interactions in the periphery and brain." Thesis, University of Cambridge, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.383316.
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Rombach, Michaela Puck. "Colouring, centrality and core-periphery structure in graphs." Thesis, University of Oxford, 2013. http://ora.ox.ac.uk/objects/uuid:7326ecc6-a447-474f-a03b-6ec244831ad4.
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Krivelevich and Patkós conjectured in 2009 that χ(G(n, p)) ∼ χ=(G(n, p)) ∼ χ∗=(G(n, p)) for C/n < p < 1 − ε, where ε > 0. We prove this conjecture for n−1+ε1 < p < 1 − ε2 where ε1, ε2 > 0. We investigate several measures that have been proposed to indicate centrality of nodes in networks, and find examples of networks where they fail to distinguish any of the vertices nodes from one another. We develop a new method to investigate core-periphery structure, which entails identifying densely-connected core nodes and sparsely-connected periphery nodes. Finally, we present an experiment and an analysis of empirical networks, functional human brain networks. We found that reconfiguration patterns of dynamic communities can be used to classify nodes into a stiff core, a flexible periphery, and a bulk. The separation between this stiff core and flexible periphery changes as a person learns a simple motor skill and, importantly, it is a good predictor of how successful the person is at learning the skill. This temporally defined core-periphery organisation corresponds well with the core- periphery detected by the method that we proposed earlier the static networks created by averaging over the subjects dynamic functional brain networks.
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Chatterjee, Niladri. "The uprising in the 'periphery' : Bengal 1857-58." Thesis, SOAS, University of London, 2015. http://eprints.soas.ac.uk/20389/.
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The thesis deals with the rebellion of 1857 - variously described as the Sepoy Mutiny or the First Indian War of Independence - in an area generally stereotyped as the periphery in the context of the rebellion. The geographical area covered in the thesis includes the lower province of the Bengal Presidency, which at present roughly incorporates the states of West Bengal and Assam in India, and Bangladesh. Using the hitherto underutilized sources this dissertation seeks to venture into the task of constructing a narrative of sequential events related to the rebellion in this region, while simultaneously analysing the moments of crises that the colonial administration had encountered during this time. The dissertation argues that in spite of the regional specificities that determined the nature, character and outcome of the movement, the rebellion was a multifaceted and multi-layered one, and the events of varying multitudes in the region were interconnected with the broader conflagration of 1857, together which brought about a crisis of the colonial rule in Indian subcontinent. While doing so, the thesis looks at the action of the rebels, the networks of communication, and the role and significance of non-traditional modes of communication, with specific focus on the circulation of rumours and panic in shaping the character of the rebellion in the region. It argues that during a moment of social and political upheaval, such as the rebellion of 1857, rumours and their consequent effect have the potential to be a source of historical analysis. As a corollary to the present study, the thesis also revisits the question of 'loyalism' of the middle class intelligentsia of Bengal during the rebellion, arguing for a more nuanced understanding of such terminologies.
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Gong, Mingliang. "Orientation discrimination in periphery: Surround suppression or crowding?" Miami University / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=miami1430433449.
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Burathoki, Tunna P. "China and peripheral conflicts." University of Southern Queensland, Faculty of Arts, 2004. http://eprints.usq.edu.au/archive/00002825/.
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[Abstract]: China’s enormous size and stature as a new hub of economic growth in tandem with its military modernisation make China a rising power. The strategic consequences of China’s economic growth synergised with its military muscles are multiple and profound, especially, for the neighbours in its conflict-prone periphery. The aim of this dissertation is not only to assess the importance and complexities of conflicts in the periphery of China, but also about the necessity for the neighbours to coexist with a more powerful China. At the same time, in the Chinese geopolitical context, domestic stability and hence, the CCP’s legitimacy has been perpetually paramount, and external threats or conflicts are usually perceived in the context of aggravating domestic and international stability, thereby hampering its strategic aim of achieving global economic command and power-projection military capability.With the dawn of 21st century, China is grooving to an exuberant global beat, the intensity of conflicts along China’s periphery has dimmed to such an extent that its political, economic, and social order will probably not disintegrate into chaos in the near future. Instead, China’s rapidly growing economic capacity and its soaring prestige in faraway capitals like Washington and Paris has meant an expansion of Chinese “soft power”, i.e., an assertive China with an ability to get what it wants by attracting and persuading others to adopt its goals, instead of blunt economic and military coercion. And, China could reasonably be expected to manage most, if not all, the conflicts in its periphery to its own advantage. These include: efforts to augment its military capabilities in a manner commensurate with its increased economic muscle and acquire new allies and underwrite the protection of others in its periphery. It is unlikely that the PRC will actually acquire new or reclaim old territory for China’s resources or for symbolic reasons by penalizing, if necessary, any opponents or bystanders who resist such claims. While it may wish to redress past wrongs it believes to have suffered; or attempt to rewrite the prevailing international “rules of game” to better reflect its own geostrategic interests; or in the most extreme policy choice, perhaps even ready itself for preventive war or to launch predatory attacks on its foes on the pretext of the “cult of defence,” – all of which have been seen as the bedrock of the contemporary China’s strategic culture, however, it is iiprobable that China will not pursue these at the cost of its future economic and/or social security agenda.
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Hörnström, Lisa. "Redistributive regionalism narratives on regionalisation in the Nordic periphery /." Umeå : Statsvetenskapliga institutionen, Umeå universitet, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-33933.
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Moore, Alison. "Queensland NRM volunteers : powerful participants or on the periphery? /." [St. Lucia, Qld.], 2006. http://www.library.uq.edu.au/pdfserve.php?image=thesisabs/absthe19433.pdf.
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Hörnström, Lisa. "Redistributive regionalism : Narratives on regionalisation in the Nordic periphery." Doctoral thesis, Umeå universitet, Statsvetenskapliga institutionen, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-33933.
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During the last decades a stronger role for the regions has developed in many West European countries. To a significant degree this regionalisation trend has coincided with European integration. The key change in the role of the regional level has been with regard to its status as an agent of regional development. In most West European countries there has been a shift from an approach to regional policy that has focused on redistributive measures from the centre in which the regions play a relatively weak role to a perspective that is sometimes labelled “new regionalism” in which the focus is on the region taking responsibility for its own development. In this new regionalist perspective, which is both descriptive and normative, the region is considered as the appropriate arena for both economic activities and decision-making. In the political systems of the Nordic countries the regional level has traditionally been in a relatively weak position and regional policy has emphasized centralisation and redistributive measures. Not unexpectedly, the pan-European trend toward a stronger role for the region has also found its way to the Nordic countries. The aim of this study is to describe and analyze if and to what extent key actors in three peripheral regions, situated in countries with a strong tradition of redistribution from the centre and a weak role for the regional level, have embraced the new regionalist perspective. The three regions are Troms in Norway, Pohjois-Pohjanmaa in Finland and Västerbotten in Sweden. All are peripherally located with small populations and economies that rely heavily on natural resources. The analysis is based on interviews with regional and local politicians, civil servants, and business representatives. The empirical material is presented in the form of narratives formulated by the regional actors who express their views on regional policy and the role of the region. The results of the study show that regional actors in the three peripheries express similar narratives. To a certain degree actors have embraced the new regionalist perspective in the sense that they see the regional level as an important coordinator for development initiatives and measures. However, the actors’ claims for a stronger regional level must be understood in the context of the unitary state. In this context, the actors’ perspective combines the new regionalist and the centralist redistributive approach, one that can be labelled ‘redistributive regionalism’. The state remains the key actor and is expected to guarantee equal conditions in all parts of the country. The emphasis on strengthening the administrative region is more pronounced in Troms and Västerbotten than in Pohjois-Pohjanmaa, where instead there is a stronger focus on the functional region. Actors in the three regions do not see any contradiction between a strong state and increased regional influence on development issues. In sum, the study finds that the new regionalist perspective has been embraced to a certain extent but that it has been adapted to national characteristics, as well as to the specific conditions in the three regions.
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Syrjänen, Elmeri. "Attention to the periphery attenuates the EPN and LPP." Thesis, Stockholms universitet, Psykologiska institutionen, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-59197.
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Current research shows that emotions have an important role in guiding attention and cognitions especially when the emotional stimuli are affective. Load theory proposes that when the perceptual load on attention is sufficiently high, irrelevant emotional stimuli is no longer attended to and thus will not produce a distracting effect. In this study 18 participants performed two discrimination tasks where their attention was manipulated spatially. To investigate the effect of spatial attention on ERP components, emotional pictures in 14 different semantic categories were shown while EEG was recorded. The results indicate that a successful perceptual load was achieved, reflected in the behavioral data that show there was a clear difference in performance between tasks. Further the results indicate that a strong effect was achieved in the mean amplitudes of both EPN and LPP corresponding to the semantic categories of pictures. Critically directing the attention to the periphery while emotionally salient pictures were presented attenuated the mean amplitude of both EPN and LPP.
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Patel, Mayur. "Mobilizing the periphery : African coalition bargaining in the WTO." Thesis, University of Oxford, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.547791.
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Pesola, Ulla-Maija. "Crossing Boundaries : Transferring eHealth services across the Northern Periphery." Doctoral thesis, Umeå universitet, Institutionen för informatik, 2013. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-68850.
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Health care organisations in Finland, Norway, Scotland and Sweden face similar challenges when it comes to providing health services in the sparsely populated rural areas. Vast distances, centralized health services, harsh climate and limited access to public transport can make accessing health services difficult. In order to provide health services for the population of the Northern Periphery it is necessary to develop health care service models which can address the problems of isolation, remoteness and centralized health services. One way of overcoming these issues is to develop eHealth services that focus on increasing access to health services in the rural areas. As health care organisations’ resources are often limited, the possibilities to develop, test and implement eHealth services can be restricted. Thus, transferring existing eHealth services across organisational and national boundaries can be beneficial, as the services have already been tested in practice. Taking advantage of the knowledge health care organisations in different countries have can support organisations in their drive to develop service provision models that reach out to the population of the Northern Periphery. The main objective of this thesis is to understand how local conditions influence the outcomes of eHealth transfer. In order to do so the transnational implementation of five eHealth services was investigated in five case studies. This research gives insight into how differences in organisational structure, ICT infrastructure and the size of the patient base impact health care organisations’ possibility to transfer and utilize existing eHealth services. In addition, this research offers rich insights into how these factors impact the sustainability of eHealth services. The case studies also illustrate how stakeholder collaboration and knowledge exchange impact the process of transferring eHealth services, and how patients’ and professionals’ level of trust in eHealth services can materialize in practice. In addition, this thesis demonstrates why the benefits obtained with a specific eHealth service may, or may not be duplicable in another organisational context. The research discussed in this thesis also contributes to the understanding of how assessing organisational readiness prior to transferring and eHealth services can facilitate the implementation process.
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Safi, Kristin Naree. "Costly signaling among great houses on the Chaco periphery." Thesis, Washington State University, 2015. http://pqdtopen.proquest.com/#viewpdf?dispub=3717464.
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Despite decades of Chaco-style great house research, the impetus for their construction and the extent to which their communities directly interacted across the northern Southwest remain poorly understood. A key question is whether great houses represent an articulated system centered at Chaco Canyon or whether they are a regional conceptualization of communal activities enacted on a local scale. The amount of documented great house variability suggests that local social and environmental contexts played an important role in the construction and use of these structures.
I present a case study of three late Pueblo II (A.D. 1050-1130) communities in the southern Cibola sub-region, located on the southern extent of the Pueblo culture area, to evaluate the role of great houses within their local and broader social contexts. I argue great houses in this area were constructed as costly signaling displays directed by local leaders to gain community prestige and access to non-local resources. I draw on survey, architectural, ceramic, faunal, and compositional data from each community to identify links between these great houses and others across the northern Southwest, examine the nature of great house use within the context of each associated community, and evaluate patterns of interaction with local and more distant communities. I then expand this analysis to evaluate evidence for costly signaling activities between great house communities from across the Chacoan sphere.
The results suggest that southern Cibola great houses were locally constructed using elements from the traditional Chaco architectural canon, and utilized remodeling events to increase their architectural link to Chaco Canyon. These great houses hosted community-integrating activities that incorporated ceramics from both the Pueblo and Mogollon ancestral traditions, possibly in an effort to socially integrate a multi-ethnic population. No evidence was identified to support the historically dominant model that southern Cibola great houses were built and controlled by Chaco Canyon populations. Based on this analysis, a costly signaling model better accounts for the construction of southern Cibola great houses than others posed for a Chaco regional system. This inference is supported at other great houses across the Chaco sphere, given the available macro-regional great house data.
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Hore, Elena. "Centre-periphery relations in Russia : the case of Siberia." Thesis, University of Essex, 2003. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.248690.
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Ovalles, Larisa. "Staging frontier dynamics : interplay at the periphery of Manaus." Thesis, Massachusetts Institute of Technology, 2016. http://hdl.handle.net/1721.1/106419.
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Thesis: S.M., Massachusetts Institute of Technology, Department of Architecture, 2016.Page 242 blank. Cataloged from PDF version of thesis.
Includes bibliographical references (pages 212-216).
The Amazonia basin has been the protagonist of many large scale infrastructural and colonization ambitions that are closely tied to larger global economic pressures. These are mainly manifest along the peripheries and edges where both deforestation and land conflict have intensified alongside rapid rates of urbanization. Increased environmental awareness and the use of nature as capital make obvious that Nature can no longer be disregarded. This sets up a scenario where the Frontier has the potential for coupling and hybridization towards a new common project, one where built space and natural space are no longer mutually exclusive, but instead work within a systematic relationship that can adapt to land use transformations through time. The Amazonian frontier is not a border or a purely linear development between settled and unsettled territory in the Turnerian sense, but a field of heterogeneity: where the interplay of actors and their interests produces a space where a series of articulated scales of temporalities and spatialities coexist. This thesis investigates the territorial implications of urbanization patterns along the Amazonian frontier as a potential space for experimentation and creation of new hybrid zones. In order to establish a new hybrid periphery growth model at the frontier which incorporates natural and built space, the project explores ecological, agrarian, and urban tools and proposes strategies of addition and subtraction, sharing and exchange in order to: connect and link disarticulated forest fragments; contain and guide development; and provide alternative hybrid and collective models for new Productive Landscapes. In doing so, the project examines the dynamics and interplay between two entities, nature and development, in order to create strategies for a collective zone that capitalizes on the dynamic quality of the Amazonian frontier.
by Larisa Ovalles.
S.M.
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Hayashi, Tomomi. "How can Architecture and Urbanism work in a Periphery?" Thesis, Virginia Tech, 1998. http://hdl.handle.net/10919/33015.
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In today's society urban liveliness has moved from the center of city to its periphery in a diluted manner. There exists the continuation of monotonous cityscape as by-product and leftover of architecture and urbanism. Herein lies the question: how to build a meaningful 'place' in a site where the sense of place is lost. This book is a record of the challenge in my belief that architecture is generous spatial entity which has both elaborated condition and quality orchestrated by the relationship to its site, structure, and material to enhance the quality of life through the human senses.Master of Architecture
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Sanghvi, Niraj D. "Parallel Computation of the Meddis MATLAB Auditory Periphery Model." The Ohio State University, 2012. http://rave.ohiolink.edu/etdc/view?acc_num=osu1339092782.
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Kantamneni, Anusha. "Identifying Communities as Core-Periphery Structures in Evolving Networks." University of Cincinnati / OhioLINK, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=ucin1470740985.
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Moenter, V. M. "Reclaiming the periphery : kinetic perimetry in patients with glaucoma." Thesis, City, University of London, 2016. http://openaccess.city.ac.uk/15073/.
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Static automated perimetry of the central 30˚ is the most often used visual field test in glaucoma patients. Short test durations are achieved by focusing on a central region, which constitutes ~20% of the visual field. However, ignoring the periphery may sacrifice information on how patients are affected functionally. Peripheral vision is important for guiding attention, balance and mobility. An efficient standard automated examination for the peripheral visual field has not been established yet. This thesis aims to lay groundwork for the development of such a test. I introduce a kinetic automated test, which estimates an isopter with three repeated presentations per meridian. I ask whether measuring a peripheral isopter adds information to central visual field test results, investigate retest reliability and evaluate the efficiency of test procedures with repeated presentations through computer simulations. Moreover, I investigate how visual field thresholds obtained with static and kinetic stimuli relate to each other and examine the influence of stimulus sizes III and V on static threshold estimates. I also investigate the relationship between response variability and contrast sensitivity in the peripheral visual field. Based on the results, I suggest using repeated presentations in automated kinetic tests. I demonstrate that data driven computer simulations are useful for the development of efficient automated kinetic perimetry. The frequency-of-seeing results suggest that response variability to static stimuli in the far periphery is lower than suggested by previous data (Henson et al., 2000). This is relevant to future computer simulations of peripheral visual field tests with static automated perimetry. As a future avenue for examining the visual field periphery I propose a combined static kinetic automated visual field test, which combines a peripheral isopter as a region of interest with static stimuli inside this region. In a separate investigation, I examine the influence of visual field damage on reading performance and evaluate the relationship between reading performance and eye movements, using a within-patient between-eye study design in glaucoma patients with asymmetrical visual field loss. Between-eye reading performance was affected by visual field loss and co-occurred with specific eye movement patterns. The within-patient between-eye design appeared to be useful for investigating the relationship between visual field loss and functional disability.
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Myers, Ethan C. "Sentence final particles in Shanghainese| Navigating the left periphery." Thesis, Purdue University, 2015. http://pqdtopen.proquest.com/#viewpdf?dispub=1598108.
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The purpose of the present study was to provide a modern syntactic analysis of Shanghainese, the regional language spoken in Shanghai, China. While Shanghainese has received significantly less exposure in the published literature compared to other regional counterparts, there is much that the language can contribute to the overall study of human language. In spite of the fact that Shanghainese has been experiencing a decline in first language learners in recent generations, this thesis aims to increase its exposure in the academic discourse and enforce the legitimacy of its standing as a distinct, living language and as a valuable piece of cultural identity that belongs to the people of Shanghai. This exposure will be specifically limited to the language’s inventory and treatment of a class of lexical items known as sentence-final particles, which encode discourse material and information about the speaker’s subjective states (e.g. surprise or assumption). These particles have been analyzed in detail in several languages by postulating the presence of rich functional fields at the upper periphery of a language’s syntactic structure. In a joint effort to introduce Shanghainese to the academic discourse and to test claims about hypothetical universal structures in an empirical fashion, this study developed two tasks to test some hypotheses about the functional field.
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Fabbietti, Silvia <1987>. "The centrality of periphery: analysis of the Indian miracle." Master's Degree Thesis, Università Ca' Foscari Venezia, 2013. http://hdl.handle.net/10579/2569.
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La presente tesi, dopo una breve panoramica della storia dell’India contemporanea, analizza i punti di forza e le anomalie dell’ascesa dell’India nell’era globalizzata, dallo sviluppo dei settori economici, alla sostenibilità di tale sviluppo, fino a un confronto con un altro gigante tra le economie emergenti, la Cina. L’intento è quello di mettere in evidenza i pro e i contro di uno sviluppo molto rapido attraverso un esempio oggi eclatante, quello dell’India.
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Roman, William. "Positioning nuclei at the periphery of skeletal muscle cells." Thesis, Paris 6, 2016. http://www.theses.fr/2016PA066408/document.
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Les mouvements nucléaires sont importants pour une multitude de fonctions cellulaires et sont induits par des forces produites par des protéines moteurs et le cytosquelette. Lors de la formation et régénération de myofibres, les noyaux migrent du centre à la périphérie de la cellule pour son bon fonctionnement. De plus, certaines maladies musculaires sont caractérisées par une accumulation de noyaux centraux. En utilisant une approche théorique et empirique, nous démontrons que le mouvement de noyaux vers la périphérie des myofibres est induit par des forces centripètes autour des noyaux ainsi que par des changements locaux de rigidité nucléaire. Ces forces centripètes sont générées par la contraction de myofibrilles et par leur réticulation autour des noyaux. Les changements de rigidité nucléaire relèvent d’une asymétrie de la distribution de la lamin A/C. En débutant par BIN1, gène muté dans les myopathies centro-nucléés (CNM), nous avons identifié la cascade moléculaire à l’origine du mouvement des noyaux. Nous montrons que l’Amphiphysin 2 (BIN1) est indispensable pour le recrutement de N-WASP, activateur du complexe Arp2/3 afin de promouvoir la polymérisation de l’actine. Cette cascade est nécessaire au mouvement des noyaux vers la périphérie et pour la formation de triades transversales. Cet enchainement est perturbé chez certains patients portant des mutations de BIN1 car cela affecte la bonne localisation de l’Amphiphysin 2. Bien que provenant de la même cascade, le mouvement des noyaux vers la périphérie et la formation transversale de triades sont des processus indépendants. Un complexe de Arp2/3 contenant Arpc5L avec la γ-actine organisent la desmine et donc la réticulation des myofibrilles important pour le mouvement nucléaire. En revanche, un complexe de Arp2/3 contenant Arpc5 avec la β-actine est nécessaires à la formation de triades transversalesNuclear movements are important for multiple cellular functions and are driven by forces originating from motor proteins and cytoskeleton. During skeletal myofiber formation or regeneration, nuclei move from the center to the periphery of the myofiber for proper muscle function. Furthermore, centrally located nuclei are found in different muscle disorders. Using theoretical and experimental approaches, we demonstrate that nuclear movement to the periphery of myofibers is mediated by centripetal forces around the nucleus in combination with local changes of nuclear stiffness. The centripetal forces are generated by myofibril contraction, cross-linking and zipping around the nucleus. Local changes of nuclear stiffness are achieved by asymmetric distribution of lamin A/C. Beginning with BIN1, gene mutated in centronuclear myopathies (CNMs); we identified the molecular cascade involved in nuclear movement to the periphery. We show that Amphipysin 2 (BIN1) is important for N-WASP recruitment which itself activates the Arp2/3 complex to induce actin polymerization. This cascade is important for nuclear movement to the periphery and transversal triad formation. This pathway is perturbed in certain patients harboring BIN1 mutations as it leads to mis-localized amphiphysin 2. Despite originating from the same pathway, peripheral nuclear movement and transversal triad formation are independent processes. An Arp2/3 complex containing Arpc5L together with γ-actin organize desmin to cross-link and zip myofibrils for nuclear movement whereas an Arp2/3 complex containing Arpc5 together with β-actin is required for transversal triad formation
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Roman, William. "Positioning nuclei at the periphery of skeletal muscle cells." Electronic Thesis or Diss., Paris 6, 2016. http://www.theses.fr/2016PA066408.
Full textAbstract:
Les mouvements nucléaires sont importants pour une multitude de fonctions cellulaires et sont induits par des forces produites par des protéines moteurs et le cytosquelette. Lors de la formation et régénération de myofibres, les noyaux migrent du centre à la périphérie de la cellule pour son bon fonctionnement. De plus, certaines maladies musculaires sont caractérisées par une accumulation de noyaux centraux. En utilisant une approche théorique et empirique, nous démontrons que le mouvement de noyaux vers la périphérie des myofibres est induit par des forces centripètes autour des noyaux ainsi que par des changements locaux de rigidité nucléaire. Ces forces centripètes sont générées par la contraction de myofibrilles et par leur réticulation autour des noyaux. Les changements de rigidité nucléaire relèvent d’une asymétrie de la distribution de la lamin A/C. En débutant par BIN1, gène muté dans les myopathies centro-nucléés (CNM), nous avons identifié la cascade moléculaire à l’origine du mouvement des noyaux. Nous montrons que l’Amphiphysin 2 (BIN1) est indispensable pour le recrutement de N-WASP, activateur du complexe Arp2/3 afin de promouvoir la polymérisation de l’actine. Cette cascade est nécessaire au mouvement des noyaux vers la périphérie et pour la formation de triades transversales. Cet enchainement est perturbé chez certains patients portant des mutations de BIN1 car cela affecte la bonne localisation de l’Amphiphysin 2. Bien que provenant de la même cascade, le mouvement des noyaux vers la périphérie et la formation transversale de triades sont des processus indépendants. Un complexe de Arp2/3 contenant Arpc5L avec la γ-actine organisent la desmine et donc la réticulation des myofibrilles important pour le mouvement nucléaire. En revanche, un complexe de Arp2/3 contenant Arpc5 avec la β-actine est nécessaires à la formation de triades transversalesNuclear movements are important for multiple cellular functions and are driven by forces originating from motor proteins and cytoskeleton. During skeletal myofiber formation or regeneration, nuclei move from the center to the periphery of the myofiber for proper muscle function. Furthermore, centrally located nuclei are found in different muscle disorders. Using theoretical and experimental approaches, we demonstrate that nuclear movement to the periphery of myofibers is mediated by centripetal forces around the nucleus in combination with local changes of nuclear stiffness. The centripetal forces are generated by myofibril contraction, cross-linking and zipping around the nucleus. Local changes of nuclear stiffness are achieved by asymmetric distribution of lamin A/C. Beginning with BIN1, gene mutated in centronuclear myopathies (CNMs); we identified the molecular cascade involved in nuclear movement to the periphery. We show that Amphipysin 2 (BIN1) is important for N-WASP recruitment which itself activates the Arp2/3 complex to induce actin polymerization. This cascade is important for nuclear movement to the periphery and transversal triad formation. This pathway is perturbed in certain patients harboring BIN1 mutations as it leads to mis-localized amphiphysin 2. Despite originating from the same pathway, peripheral nuclear movement and transversal triad formation are independent processes. An Arp2/3 complex containing Arpc5L together with γ-actin organize desmin to cross-link and zip myofibrils for nuclear movement whereas an Arp2/3 complex containing Arpc5 together with β-actin is required for transversal triad formation
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Nilsson, David. ""Bara att gilla läget" : Ungdomar i Södermöre och förhållandet till centralorten Kalmar." Thesis, University of Kalmar, School of Human Sciences, 2008. http://urn.kb.se/resolve?urn=urn:nbn:se:hik:diva-483.
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The purpose of this essay has been to find out how adolescents from Södermöre in the municipality of Kalmar experience the central place Kalmar. It has also been the intention to make clear, whether the relation between the adolescents and the central place Kalmar could be described as a centre-periphery-relation. The basis of this essay has been interviews of all together nine adolescents.
A centre-periphery-situation can according to the theory be discovered by analyzing three categories: culture, economy and politics. If the centre dominates the periphery in one of these three categories, a centre-periphery-situation exists. The theory also says that the people living in the periphery experience less kinship with the people living in the centre.
The adolescents from Södermöre showed to experience the central place Kalmar in a way, that can be described in five categories: travelling mostly by bus, unfair distribution of the resources of the municipality, political equality, social equality and the awareness of the central place Kalmar as the place ‘where everything is located’.
When it came to economy and politics, no indications of a centre-periphery-situation were found during the interviews with the adolescents. However, culturally the adolescents from Södermöre seemed to experience domination from the central place Kalmar. This domination was strengthened by the experience of bad bus services.
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Pociūtė, Gintarė. "Periferingumo teritorinė raiška Lietuvoje." Doctoral thesis, Lithuanian Academic Libraries Network (LABT), 2014. http://vddb.library.lt/obj/LT-eLABa-0001:E.02~2014~D_20140512_103814-60982.
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Mokslinių darbų, teoriškai ar praktiškai akcentuojančių periferingumo tematiką išties yra nemažai, tačiau iki šiol nėra aiškiai ir galutinai apibrėžta periferinio regiono samprata, be to, retai kalbama apie periferizacijos procesą ar nustatomas regionų periferingumo laipsnis. Periferijos tyrimuose jaučiamas geografinio-kompleksinio požiūrio į periferiją trūkumas. Mokslų integracija analizuojant pasirinktą problemą yra viena pagrindinių rekomendacijų, kadangi siauras požiūris į periferiją nebeatitinka šių dienų aktualijų, nes stabdo ne tik objekto sampratos vystymąsi, bet ir apriboja pačios periferijos kaip teritorinio reiškinio pažinimo galimybes. Šiuo moksliniu darbu siekiama užpildyti trūkstamą periferingumo tyrimų nišą ir prisidėti prie periferijos kompleksinės geografinės sampratos vystymo. Disertacijoje periferijos kompleksinis vertinimas atliekamas remiantis septyniais vertinimo aspektais: pasiekiamumo, demografiniu, socialiniu, ekonominiu, kultūriniu, politiniu bei gamtiniu. Šis disertacinis darbas – tai bandymas, apjungiant įvairių sričių rodiklius, pateikti kompleksinį požiūrį į periferiją, remiantis statistikos rodiklių reikšmėmis išskirti skirtingo periferingumo laipsnio periferinius regionus Lietuvos teritorijoje.There are a lot of scientific papers, which theoretically or practically accentuate the topic of peripherality, however, the conception of peripheral region is not still clearly and finally defined, moreover, it is rarely talked about the process of peripheralisation or the level of peripherality of region is determined. It is felt the lack of the geographic-complex view to the periphery. While analyzing the selected problem the integration of sciences is one of the main recommendations as the narrow attitude to the periphery does not conform to the topicalities of these days because it stops not only the development of conception of object but also limits the cognitive possibilities of periphery itself as the territorial phenomenon. By this scientific paper it is tried to fill the deficient part of researches on peripherality and add to the development of complex geographical conception of periphery. In the dissertation thesis the complex evaluation is performed taking into account seven aspects: dislocation, demographic, social, economic, cultural, political and natural. This dissertation paper is an attempt to present the complex attitude to the periphery while including the indicators of various fields, with reference to the values of statistical indicators to distinguish the peripheral regions of different level peripherality in the territory of Lithuania.
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Hentschel, Nicole [Verfasser]. "Mechanisms of immunotherapy in Alzheimer’s disease : testing the peripheral sink hypothesis by restricting Aβ-antibodies to the periphery / Nicole Hentschel." Berlin : Medizinische Fakultät Charité - Universitätsmedizin Berlin, 2013. http://d-nb.info/1032558644/34.
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Lee, Mi-kyung. "Exploring the left periphery: the cases of Korean and Spanish." Doctoral thesis, Universitat Autònoma de Barcelona, 2020. http://hdl.handle.net/10803/669520.
Full textAbstract:
Aquesta tesi tracta sobre la perifèria esquerra de coreà i espanyol des de la perspectiva de lingüística comparada. Aquest treball ofereix dades empíriques de in-situ de focus/Qu-/tòpic, scrambling i topicalització en coreà, que sembla que no és compatible amb la cartografia (Rizzi 1997 i següents). A més d’això, aquesta tesi proposa un sistema uniforme dins de la perifèria esquerra a més d’un sistema entre les dues llengües basat en l’anàlisi ofert per a espanyol i coreà en aquest treball. Aquesta tesi està enfocada en FinP i moviment encobert.Esta tesis trata de la periferia izquierda de coreano y español desde perspectiva de lingüística cruzada. Este trabajo ofrece datos empíricos de in-situ de focus/Qu-/tópico, scrambling y topicalización en coreano, que parece que no es compatible con la cartografía (Rizzi 1997 y siguientes). Además de esto, esta tesis propone un sistema uniforme dentro de la periferia izquierda además de un sistema paramétrico entre las dos lenguas basado en el análisis ofrecido para español y coreano en este trabajo. Esta tesis está enfocada en FinP y movimiento encubierto.
This dissertation deals with the Left Periphery of Korean and Spanish from a cross-linguistic perspectives. This work provides empirical data of in-situ of focus/wh/topic,scrambling and topicalization in Korean, which seem to be not compatible with the cartographic project (Rizzi 1997 et seq.). In addition to this, this dissertation proposes a uniform system within Left Periphery as well as parametric system betweeen the two languages based on the adduced analysis for Spanish and Korean in this work. This dissertation focuses on FinP and covert movement.
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Murillo, Edwin. "Uncanny Periphery: Existential(ist) Latin American Narratives of the 1930s." Scholarly Repository, 2009. http://scholarlyrepository.miami.edu/oa_dissertations/267.
Full textAbstract:
This dissertation investigates the narrative practice of Latin American Existentialism. My project tracks the structures, themes, and interpretations of Existentialism across national borders in the belief that a common expression exists which is distinctly Latin American. I begin this philosophical cartography, with four Existential(ist) novels produced in Latin America during the 1930s. Specifically, I will examine the Existentialist quality of Enrique Labrador Ruiz's El laberinto de si mismo (1933), Maria Luisa Bombal's La ultima niebla (1934) and La amortajada (1938), and Graciliano Ramos's Angustia (1936). These narratives are analyzed in relation to the core thematic of Existential philosophy. I read these narratives as Existential(ist) because they are of, relating to and characterized by a philosophy of existence, and because they simultaneously produce an Existential discourse. My study is, at one level, comparative in that I pursue the points of emergence of Existentialism's prominent categories not only across national borders, but also across disciplines. I relate the tradition of Latin American thought in the first half of the 20th century and Existential philosophy from Europe to collectivize the thematic points of contact. These I contrast with our literary production of the 1930s. By emphasizing the particularities and continuations of Latin America's contribution to the Existential canon I, in effect, periodize an era which is foundational in the history of Latin American literature. Furthermore, by acknowledging the literary presence of Latin American Existentialism we can appreciate the explicit narrative interrogation of the Self through aesthetic, ethical, and ontological parameters.
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Barnes, Cedric Richard. "The Ethiopian state and its Somalia periphery, circa 1888-1948." Thesis, University of Cambridge, 2001. https://www.repository.cam.ac.uk/handle/1810/251755.
Full textAbstract:
This thesis examines the regional history of the western Somali lands that were incorporated into the Ethiopian Empire at the turn of the last century. The study is about the changing nature of centre and periphery in Ethiopia, and the evolution of statehood in the region. Its primary focus is the economical and political relationship between Somalis and the representatives of the Ethiopian state, and how these relationships were affected by the emergence of rival colonial administrations that also claimed to govern Somalis. The thesis first addresses the role of the periphery in the history of the expansion of the modern Ethiopian state. It is argued with recent Ethiopian historians that the state Menilek created was primarily about diverting the demands of a militarised system away from the centre into new lands in order to create a sustainable standing army with which to assert political supremacy. However this militarised state was soon found to be too anachronistic, devolved and cumbersome and did not manage well the transition which came with the death of Menilek. The next two chapters show how the periphery was used as a resource with which to compete in the battle for power at the centre. This was a struggle from which Tafari (later Emperor Hayla Sellase), the governor of a peripheral province in the east emerged as victor. The second half of the thesis goes on to argue that once the centre was won the eastern periphery continued to play an important part in the modern centralist project. Since this was one of the points at which Ethiopia communicated with the outside world in both political and economic terms, the periphery was peculiarly important in the evolution of the sovereignty of the modern Ethiopian state. However the latter part of the study shows how the political and economic articulation of the eastern periphery with neighbouring colonial states, especially the growth of markets and improvement in infrastructure there, progressively weakened Ethiopian sovereignty and precipitated the Italian invasion.