Relevant bibliographies by topics / Peripheral pulmonary lesion

Academic literature on the topic 'Peripheral pulmonary lesion'

Author: Grafiati
Published: 10 December 2022
Last updated: 28 January 2023

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Journal articles on the topic "Peripheral pulmonary lesion"

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Shepherd, Ray W. "Bronchoscopic pursuit of the peripheral pulmonary lesion." Current Opinion in Pulmonary Medicine 22, no. 3 (May 2016): 257–64. http://dx.doi.org/10.1097/mcp.0000000000000273.

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Steinfort, Daniel P., Asha Bonney, Katharine See, and Louis B. Irving. "Sequential multimodality bronchoscopic investigation of peripheral pulmonary lesions." European Respiratory Journal 47, no. 2 (November 5, 2015): 607–14. http://dx.doi.org/10.1183/13993003.00786-2015.

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Multiple guidance modalities may be combined during bronchoscopic investigation of peripheral pulmonary lesions (PPLs). The relative contribution of each modality to diagnostic performance remains uncertain.Endobronchial ultrasound (EBUS) with virtual bronchoscopy (VB) was routinely performed, with electromagnetic navigation (EMN) utilised only where EBUS was unable to locate PPLs or where the probe was adjacent to the lesion and on-site cytologic examination was nondiagnostic.236 consecutive patients with 245 PPLs had lesion size 22.8±12.4 mm (mean±sd). PPLs were localised using EBUS+VB alone in 188 (77%) and was diagnostic in 134 of these (71.3%). EBUS localisation was predicted by PPL size (23.7±10.5versus19.7±9.8 mm, p=0.003), but not by bronchus sign, PPL–hilum distance or PPL–pleura distance. EMN in 57 patients achieved EBUS localisation in a further 17 patients (30.9%), improving overall visualisation yield to 85%. Nine of these 57 procedures achieved a definitive diagnosis (16%), improving overall diagnostic yield to 58.4%. Probe position and lesion type influenced overall diagnostic yield. Sensitivity for diagnosis of lung cancer was 70% (131/188; 95% CI 63–76%).Localisation rate and diagnostic sensitivity of radial probe EBUS+VB alone for diagnosis of PPLs is high. EBUS localisation rates and procedural yield are improved only modestly (by 8% and 4%, respectively) with addition of EMN. Sampling following EMN should include all available methods to maximise diagnostic yield.
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Jacomelli, Marcia, Sergio Eduardo Demarzo, Paulo Francisco Guerreiro Cardoso, Addy Lidvina Mejia Palomino, and Viviane Rossi Figueiredo. "Radial-probe EBUS for the diagnosis of peripheral pulmonary lesions." Jornal Brasileiro de Pneumologia 42, no. 4 (August 2016): 248–53. http://dx.doi.org/10.1590/s1806-37562015000000079.

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ABSTRACT Objective: Conventional bronchoscopy has a low diagnostic yield for peripheral pulmonary lesions. Radial-probe EBUS employs a rotating ultrasound transducer at the end of a probe that is passed through the working channel of the bronchoscope. Radial-probe EBUS facilitates the localization of peripheral pulmonary nodules, thus increasing the diagnostic yield. The objective of this study was to present our initial experience using radial-probe EBUS in the diagnosis of peripheral pulmonary lesions at a tertiary hospital. Methods: We conducted a retrospective analysis of 54 patients who underwent radial-probe EBUS-guided bronchoscopy for the investigation of pulmonary nodules or masses between February of 2012 and September of 2013. Radial-probe EBUS was performed with a flexible 20-MHz probe, which was passed through the working channel of the bronchoscope and advanced through the bronchus to the target lesion. For localization of the lesion and for collection procedures (bronchial brushing, transbronchial needle aspiration, and transbronchial biopsy), we used fluoroscopy. Results: Radial-probe EBUS identified 39 nodules (mean diameter, 1.9 ± 0.7 cm) and 19 masses (mean diameter, 4.1 ± 0.9 cm). The overall sensitivity of the method was 66.7% (79.5% and 25.0%, respectively, for lesions that were visible and not visible by radial-probe EBUS). Among the lesions that were visible by radial-probe EBUS, the sensitivity was 91.7% for masses and 74.1% for nodules. The complications were pneumothorax (in 3.7%) and bronchial bleeding, which was controlled bronchoscopically (in 9.3%). Conclusions: Radial-probe EBUS shows a good safety profile, a low complication rate, and high sensitivity for the diagnosis of peripheral pulmonary lesions.
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Ikezoe, J., S. Morimoto, M. Akira, J. Arisawa, S. Takashima, K. Tomoda, K. Nakanishi, et al. "Computed Tomography following Endoscopic Sclerotherapy of Esophageal Varices." Acta Radiologica 28, no. 4 (July 1987): 415–20. http://dx.doi.org/10.1177/028418518702800409.

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Computed tomography of the chest following endoscopic injection sclerotherapy for esophageal varices was performed in 17 procedures in 13 patients. CT scans were obtained before and within 48 hours after the procedure. CT findings included: esophageal wall thickening; a low-attenuating lesion within the wall of the esophagus with varying appearances, either laminated, localized, or inhomogeneous; a mediastinal lesion; pleural effusion; and various types of pulmonary changes such as atelectasis, pleural-based lesions, dilatation of peripheral pulmonary vessels, and nodular lesions. However, on follow-up CT they had regressed or disappeared. The changes in the mediastinum and pleural space might be caused by direct extension of inflammation from the esophagus, but those in the lungs, especially dilatation of peripheral vessels, may be caused by the sclerosing agent passing to the pulmonary vessels.
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Kang, Do Kyun, Min Kyun Kang, Woon Heo, Youn-Ho Hwang, and Ji Yeon Kim. "Primary Pulmonary Undifferentiated Pleomorphic Sarcoma: A Rare Malignant Lung Tumor." Journal of Investigative Medicine High Impact Case Reports 9 (January 2021): 232470962110085. http://dx.doi.org/10.1177/23247096211008593.

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We report a case of a 56-year-old man with persistent right upper lobe cavitary mass. A chest computed tomography scan showed about 4-cm-sized mass with internal low attenuation and peripheral enhancement in right upper lobe apical segment. The lesion size increased over 1 month. Right upper lobectomy was performed with the intention to treat the lesion. Pathological examination showed primary pulmonary undifferentiated pleomorphic sarcoma. We describe this rare lung disease to remind that primary pulmonary undifferentiated pleomorphic sarcoma could be the differential diagnosis of pulmonary cavitary mass lesions.
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Ma, Xi, Zhi-Yan Lu, Yan-Juan Qu, Li-Hong Xing, Yu Zhang, Yi-Bo Lu, Li Dong, et al. "Differences in Clinical and Imaging Features between Asymptomatic and Symptomatic COVID-19 Patients." International Journal of Clinical Practice 2022 (December 14, 2022): 1–13. http://dx.doi.org/10.1155/2022/4763953.

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Objectives. The clinical and imaging features of asymptomatic carriers of severe acute respiratory syndrome coronavirus 2 and symptomatic COVID-19 patients. Methods. The clinical and chest computed tomography imaging data of 47 asymptomatic carriers and 36 symptomatic COVID-19 patients were derived. All patients underwent 4–6 CT scans over a period of 2–5 days. Results. The bulk of asymptomatic carriers who developed symptoms and most of the COVID-19 patients were older than 18 years of age with a decreased lymphocyte count, abnormal hepatic and renal function, and increased D-dimer and C-reactive protein. In the early stage, the pulmonary lesion involved mostly 1–2 lobes at the peripheral area in asymptomatic carriers but more than three lobes at both the central and peripheral areas in COVID-19 patients. In the progression stage, the lesion of asymptomatic carriers extended from the peripheral to the central area, and no significant difference was found in the lesion range compared with the symptomatic control group. In early improvement stage, the lesion was rapidly absorbed, and lesions were located primarily at the peripheral area in asymptomatic carriers; contrastingly, lesions were primarily located at both the central and peripheral areas in symptomatic patients. Asymptomatic carriers reflected a significantly shorter duration from disease onset to peak progression stage compared with the symptomatic. Conclusions. Asymptomatic carriers are a potential source of transmission and may become symptomatic COVID-19 patients despite indicating less severe pulmonary damage, earlier improvement, and better prognosis. Early isolation and intervention can eliminate such carriers as potential sources of transmission and improve their prognosis.
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Herth, Felix J. F. "E26. Early stage peripheral lesion." Lung Cancer 49 (July 2005): S44—S45. http://dx.doi.org/10.1016/s0169-5002(05)80089-3.

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Shah, Krunal, Abhishek Kumar, Arun Kumar, Nuthan Kumar, Prakruthi Kaushik, Avinash Thumallapalli, Bandagadde Srinivas Aruna Kumari, and Lingegowda Appaji. "Pulmonary Aspergillosis Silently Presenting as Pneumothorax in Children with Leukemia: A Report of Three Cases." Indian Journal of Medical and Paediatric Oncology 43, no. 05 (October 2022): 439–42. http://dx.doi.org/10.1055/s-0042-1755545.

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AbstractAspergillosis causes invasive pulmonary disease in patients with hematological malignancies. Children with invasive pulmonary aspergillosis (IPA) usually have nonspecific radiographic findings unlike cavitary lesions commonly seen in adults. Pneumothorax due to rupture of peripheral fungal lesion may be a severe complication in patients with neutropenia. Here, we describe three children during induction chemotherapy for B-lymphoblastic leukemia with pneumothorax as a presenting feature of pulmonary aspergillosis.
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Li, Guangsheng, Jie Huang, Yuechuan Li, and Jing Feng. "The Value of Combined Radial Endobronchial Ultrasound-Guided Transbronchial Lung Biopsy and Metagenomic Next-Generation Sequencing for Peripheral Pulmonary Infectious Lesions." Canadian Respiratory Journal 2020 (April 6, 2020): 1–9. http://dx.doi.org/10.1155/2020/2367505.

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Background. Metagenomic next-generation sequencing (mNGS) is a new technology that allows for unbiased detection of pathogens. However, there are few reports on mNGS of lung biopsy tissues for pulmonary infection diagnosis. In addition, radial endobronchial ultrasound (R-EBUS) is widely used to detect peripheral pulmonary lesions (PPLs), but it is rarely used in the diagnosis of peripheral lung infection. Objective. The present study aims to evaluate the combined application of R-EBUS-guided transbronchial lung biopsy (TBLB) and mNGS for the diagnosis of peripheral pulmonary infectious lesions. Methods. From July 2018 to April 2019, 121 patients from Tianjin Medical University General Hospital diagnosed with PPLs and lung infection were enrolled in this prospective randomized study . Once the lesion was located, either TBLB or R-EBUS-guided-TBLB was performed in randomly selected patients, and mNGS was applied for pathogen detection in lung biopsy tissues. The results of mNGS were compared between the TBLB group and R-EBUS-guided TBLB group. In addition, the clinical characteristics and EBUS images from 61 patients receiving bronchoscopy for peripheral lung infectious detection were analyzed and compared with the results of mNGS. Results. The positivity rate of mNGS in R-EBUS-guided TBLB was (78.7%, 48/61) that was significantly higher than (60.0%, 36/60) in the TBLB group. Difference in the position of R-EBUS probe and image characteristics of peripheral lung infectious lesions affected the positivity rate of mNGS. Tissue collected by R-EBUS within the lesion produced higher positivity rate than samples collected adjacent to the lesion (P=0.030, odds ratio 17.742; 95% confidence interval, from 1.325 to 237.645). Anechoic areas and luminant areas of ultrasonic image characteristics were correlated with lower positivity rate of mNGS (respectively, P=0.019, odds ratio 17.878; 95% confidence interval, from 1.595 to 200.399; P=0.042, odds ratio 16.745; 95% confidence interval, from 1.106 to 253.479). Conclusions. R-EBUS-guided TBLB is a safe and effective technique in the diagnosis of peripheral lung infectious lesions. R-EBUS significantly facilitates the accurate insertion of bronchoscope into the lesions, which improves positivity rate of mNGS analysis in pathogen detection. The R-EBUS probe position within lesion produced a higher positivity rate of mNGS analysis. Nevertheless, the presence of anechoic and luminant areas on ultrasonic image was correlated with poor mNGS positivity rate.
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Miller, K., and J. Hutter. "Technical report: Videothoracoscopic resection of a peripheral pulmonary lesion." Minimally Invasive Therapy 2, no. 1 (January 1993): 11–12. http://dx.doi.org/10.3109/13645709309152654.

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Dissertations / Theses on the topic "Peripheral pulmonary lesion"

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Torky, Mohamed Samy Mahmoud. "Endobronchial ultrasound guided transbronchial cryobiopsy in peripheral lung lesions." Doctoral thesis, Universitat Autònoma de Barcelona, 2018. http://hdl.handle.net/10803/665924.

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Introducción: La Ultrasonografía Endobronquial con sonda radial (USEB-R) es una técnica moderna para el diagnóstico de lesiones pulmonares periféricas. La adición de la Criobiopsia Transbronquial (CBTB) incrementa en rendimiento diagnóstico de la USEB-R. Objetivos: el objetivo del estudio es evaluar la eficacia y seguridad de la CBTB guiada por USEB-R en el diagnóstico de lesiones pulmonares periféricas. Objetivos secundarios son detectar los factores que pueden afectar a la eficacia de la biopsia guiada por USEB-R y evaluar la eficacia del procedimiento cuando la CBTB está contraindicada. Métodos: Se incluyeron 60 pacientes con lesiones pulmonares periféricas y se dividieron en dos grupos. El grupo I incluyó 45 pacientes que fueron elegibles para CBTB y se sometieron a biopsia transbronquial con fórceps (BTB) y CBTB guiada por USEB-R. El grupo II incluyó 15 pacientes que no fueron elegibles para CBTB y sólo se sometieron a BTB con fórceps y/o procedimientos citológicos guiados por USEB-R. Se analizaron los resultados clínicos, incluido el soporte digital de las variables cualitativas y cuantitativas. Además, se registraron las complicaciones. Resultados: En el grupo I, la BTB con fórceps tuvo una sensibilidad, especificidad, valor predictivo positivo (VPP), valor predictivo negativo (VPN) y precisión del 67.5%, 100%, q00%, 18.8% y 69.8% respectivamente. Mientras que la CBTB tuvo una sensibilidad, especificidad, valor predictivo positivo (VPP), valor predictivo negativo (VPN) y precisión del 75%, 100%, 100%, 32.1% y 76.7% respectivamente. La CBTB obtuvo un mayor rendimiento diagnóstico y mejor calidad de las muestras. La sensibilidad el grupo II fué del 80% y los resultados globales de ambos grupos demostraron una sensibilidad, especificidad, valor predictivo positivo (VPP), valor predictivo negativo (VPN) y precisión del 85.2%, 100%, 100%, 42.8% y 86.7% respectivamente. En cuanto a las complicaciones, 12 pacientes (20%) presentaron hemorragia, pero de ellos, 11 (18.3%) presentaron hemorragia moderada (grado II) y sólo 1 (1.7%) presentó hemorragia significativa (grado III). Un pacientes (1.7%) tuvo un neumotórax y otro (1.7%) sufrió de hipoxemia. Conclusiones: La CBTB guiada por USEB-R es una técnica segura y efectiva para el diagnóstico de lesiones pulmonares periféricas. La CBTB puede obtener un mayor valor diagnóstico que la BTB con fórceps debido a una mayor calidad y cantidad de las muestras. La adecuada selección de los pacientes incluidos es esencial para evitar posibles complicaciones asociadas a la CBTB.
Introduction: Radial probe endobronchial ultrasound (RP-EBUS) is a modern technique for diagnosis of peripheral lung lesions. The addition of transbronchial cryobiopsy (TBCB) could increase the diagnostic value for RP-EBUS. Objectives: The main objective is to evaluate the efficacy and safety of RP-EBUS guided TBCB for diagnosis of peripheral lung lesions. Secondary objectives are detecting factors that could affect the efficacy of RP-EBUS guided biopsy and evaluating the efficacy of the procedure when TBCB is contraindicated. Methods: 60 patients with peripheral lung diseases were included and divided into two groups. Group I included 45 patients who were eligible for TBCB and they subjected to forceps transbronchial biopsy (forceps TBB) and TBCB guided by RP-EBUS. Group II included 15 patients who were not eligible for TBCB and they subjected only to forceps TBB and / or cytology retrieval procedures guided by RP-EBUS. The diagnostic outcomes including digital assessment for qualitative and quantitative measures of collected samples were detected. Also, the associated complications were recorded. Results: In group I, forceps TBB had sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and accuracy of; 67.5%, 100%, 100%, 18.8% and 69.8% respectively. While TBCB had sensitivity, specificity, PPV, NPV and accuracy of 75%, 100%, 100%, 23.1%, 76.7% respectively. TBCB has achieved higher diagnostic values and better quality of samples. The sensitivity in group II was 80% and the overall results including both groups were sensitivity, specificity, PPV, NPV and accuracy of 85.2%, 100%, 100%, 42.8% and 86.7% respectively. Regarding the complications, 12 patients (20%) had bleeding but 11 (18.3%) of them had moderate bleeding (grade II) and only one patient (1.7%) had significant bleeding (grade III). One patient (1.7%) had pneumothorax and another patient (1.7%) suffered from hypoxemia. Conclusions: RP-EBUS guided TBCB is a safe and effective technique for diagnosis of peripheral lung lesions. TBCB could achieve higher diagnostic value than forceps TBB due to better quantity and quality of the samples. Proper selection of included patients is essential to avoid serious complications that could be associated with TBCB.
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Wong, Michelle Xin Zhi. "The peripheral pulmonary lesion - bronchoscopic techniques to improve diagnosis." Thesis, 2020. https://hdl.handle.net/2440/133292.

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Lung cancer is a leading cause of cancer-related deaths worldwide. This is no different in Australia where it is the main cause of cancer-related mortality, and the fifth most commonly cancer diagnosed in Australians. The recent National Lung Screening Trial demonstrated an improvement in mortality when patients deemed high risk for lung cancer underwent annual screening with low dose computed tomography imaging. Nearly 25% of participants were shown to have imaging suspicious for lung cancer. In light of these results, and with the possibility of increased uptake of screening, it is very likely that the incidence of identified peripheral pulmonary lesions (PPL) will only continue to rise. In evaluating PPLs, standard bronchoscopic investigation involves obtaining transbronchial forceps biopsies (TB-FB). However TBFB has variable diagnostic sensitivity, influenced by factors such as lesion size and position. The introduction of radial endobronchial ultrasound (RP-EBUS) has helped improve diagnostic yields further. Ultrasound images obtained by the miniprobe reflect the underlying structure of the peripheral lesion being examined and RPEBUS is now a well-established technique in the evaluation of PPLs. The overall aim of this thesis was to examine innovative bronchoscopic techniques which could further aid diagnostic yield in investigating PPLs. Methods (i) Radial Endobronchial Ultrasound Greyscale Texture Analysis Using Whole-Lesion Analysis Can Characterise Benign and Malignant Lesions without Region-of-Interest Selection Bias Custom software was developed to analyse RP-EBUS images based on first and second order greyscale texture features. Unconstrained ROIs were mapped onto lesions. Features from expert and nonexpert defined ROIs were compared, as were results of image analysis to tissue histology. (ii) Radial Endobronchial Ultrasound with Transbronchial Cryobiopsy versus Radial EBUS alone for the Diagnosis of Peripheral Pulmonary Lesions Prospective, single-centre randomised controlled trials of patients with PPLs. Patients were randomised to receive either one transbronchial cryobiopsy (TB-CB) sample, or 5 TB-FB samples. Results (i) Greyscale texture analysis of RP-EBUS images using unconstrained regions of interest (ROIs) demonstrated 5 features which were significantly different between benign and malignant lesions. Highest positive predictive values were associated with maximal and range of pixel intensities. No significant differences were seen between expert and non-expert-defined ROIs. (ii) 28 lesions were evaluated with overall diagnostic yield 76.7%. Diagnostic yields of TB-CB and TB-FB were 91.7% and 68.8% respectively (p=0.14). Median size of TB-CB was 7.0mm compared to 2.55mm (p<0.0001). There were no major complications with either technique. Conclusion Timely diagnosis of PPLs is critical to enable disease staging and to guide initiation of appropriate definitive treatment. Greyscale image analysis and texture analysis using the whole RP-EBUS image as a ROI can assist in distinguishing between malignant and benign lesions. This is a potentially valuable additional clinical tool in the diagnosis of peripheral lesions. However further validation is required. Cryotherapy has provided an alternative method of obtaining transbronchial biopsies (TBBs). Not only does it provide significantly larger biopsy sample, which is advantageous for further immunohistochemical and molecular analysis, but it also could be superior in diagnosing lesions which are not easily accessible by TB-FB.
Thesis (MPhil) -- University of Adelaide, Adelaide Medical School, 2021
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Chen, Hung-Jen, and 陳鴻仁. "Ultrasound in Peripheral Pulmonary Air-fluid Lesions: Color Doppler Imaging as an Aid in Differentiating Empyema and Abscess." Thesis, 2010. http://ndltd.ncl.edu.tw/handle/17936274043326937861.

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碩士
中國醫藥大學
臨床醫學研究所碩士班
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Background: The aim of this study was to re-evaluate the clinical significance of sonographic appearances, in particular the application of color Doppler ultrasound (US) imaging, in discriminating peripheral air-fluid lung abscess from empyema. Methods: We retrospectively collected those patients who had had peripheral air-fluid lesions due to empyema or lung abscess, and undergone color Doppler US and gray-scale US examinations between January 2003 and October 2007. A total of 34 patients with confirmed lung abscess and 30 patients with empyema were identified. Four sonographic characteristics were observed and analyzed: 1. the wall characteristics of the lesions (wall width, luminal margin, outer margin and chest wall angle); 2. split pleura sign; 3. internal echogenicity (suspended microbubble sign, complex-septated effusions and passive atelectasis); 4. identification of color Doppler US vessel signals in peri-cavitary lesions (consolidation or atelectasis). Results: Among the sonographic characteristics, complex-septated effusions and passive atelectasis were specific for empyema, but the sensitivity was only 40% (12/30) and 47% (14/30), respectively. Identification of color Doppler US vessel signals in peri-cavitary consolidation was the most useful and specific for lung abscess. In our series, if we define the identification of color Doppler US vessel signals in peri-cavitary consolidation as a predictor for peripheral lung abscess, we can achieve sensitivity, specificity, positive predictive value and negative predictive value of 94%, 100%, 100% and 94%, respectively. Conclusions: Color Doppler US is powerful in differentiating the peripheral air-fluid abscess from empyema, with high specificity and without any risk.
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Books on the topic "Peripheral pulmonary lesion"

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Waldmann, Carl, Neil Soni, and Andrew Rhodes. Obstetric emergencies. Oxford University Press, 2011. http://dx.doi.org/10.1093/med/9780199229581.003.0031.

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Pre-eclampsia 518Eclampsia 520HELLP syndrome 522Postpartum haemorrhage 524Amniotic fluid embolism 526Pre-eclampsia is a common complication of pregnancy, UK incidence is 3–5%, with a complex hereditary, immunological and environmental aetiology.Abnormal placentation is characterized by impaired myometrial spiral artery relaxation, failure of trophoblastic invasion of these arterial walls and blockage of some vessels with fibrin, platelets and lipid-laden macrophages. There is a 30–40%, reduction in placental perfusion by the uterine arcuate arteries as seen by Doppler studies at 18–24 weeks gestation. Ultimately the shrunken, calcified, and microembolized placenta typical of the disease is seen. The placental lesion is responsible for fetal growth retardation and increased risks of premature labour, abruption and fetal demise. Maternal systemic features of this condition are characterized by widespread endothelial damage, affecting the peripheral, renal, hepatic, cerebral, and pulmonary vasculatures. These manifest clinically as hypertension, proteinuria and peripheral oedema, and in severe cases as eclamptic convulsions, cerebral haemorrhage (the most common cause of death due to pre-eclampsia in the UK), pulmonary oedema, hepatic infarcts and haemorrhage, coagulopathy and renal dysfunction....
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Howard, Tamara Ann. Post-lesion reactions of axons in a peripheral nerve of the gastropod Melampus bidentatus (Pulmonata basommatophora). 1988, 1988.

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Rahimi, Kazem. Chronic heart failure. Edited by Patrick Davey and David Sprigings. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199568741.003.0092.

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The European Society of Cardiology defines heart failure as a clinical syndrome in which patients have the following features: symptoms typical of heart failure (breathlessness, fatigue, ankle swelling); signs typical of heart failure (tachycardia, tachypnoea, pulmonary crackles, pleural effusion, raised jugular venous pressure, peripheral oedema, hepatomegaly); and objective evidence of a structural or functional abnormality of the heart at rest (cardiomegaly, third heat sound, cardiac murmurs, abnormality on the echocardiogram, raised natriuretic peptide concentration). Heart failure results in activation of the sympathetic nervous system and the renin–aldosterone–angiotensin system, and release of a number of hormones such as natriuretic peptides, and cytokines, including tumour necrosis factor amongst others. While neurohormone activation is initially compensatory and helps in the short term to maintain circulatory needs, ultimately it has detrimental effects on the myocardium and compromises its function further. These mechanisms are therefore therapeutic targets to improve symptoms and lessen the risk of death.
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Book chapters on the topic "Peripheral pulmonary lesion"

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Kurimoto, Noriaki, and Katsuhiko Morita. "EBUS-GS for Peripheral Pulmonary Lesions." In Bronchial Branch Tracing, 127–41. Singapore: Springer Singapore, 2020. http://dx.doi.org/10.1007/978-981-13-9905-3_3.

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Kurimoto, Noriaki, Hiroaki Osada, and Teruomi Miyazawa. "Endobronchial Ultrasonography for Peripheral Pulmonary Lesions." In Clinical Chest Ultrasound, 160–65. Basel: KARGER, 2009. http://dx.doi.org/10.1159/000210421.

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Matsumoto, Yuji, and Takehiro Izumo. "Virtual Bronchoscopic Navigation for Peripheral Pulmonary Lesions." In Respiratory Endoscopy, 143–50. Singapore: Springer Singapore, 2016. http://dx.doi.org/10.1007/978-981-287-916-5_20.

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Izumo, Takehiro. "Tomography-Guided Transbronchial Biopsy for Peripheral Pulmonary Lesions." In Respiratory Endoscopy, 103–8. Singapore: Springer Singapore, 2016. http://dx.doi.org/10.1007/978-981-287-916-5_15.

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Matsumoto, Yuji, and Takehiro Izumo. "Endobronchial Ultrasound with a Guide Sheath for Peripheral Pulmonary Lesions." In Respiratory Endoscopy, 125–36. Singapore: Springer Singapore, 2016. http://dx.doi.org/10.1007/978-981-287-916-5_18.

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Takai, Moto, and Takehiro Izumo. "Transbronchial Needle Aspiration Through a Guide Sheath for Peripheral Pulmonary Lesions." In Respiratory Endoscopy, 137–42. Singapore: Springer Singapore, 2016. http://dx.doi.org/10.1007/978-981-287-916-5_19.

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Tsuchida, Takaaki. "Identification of the Involved Bronchus to Peripheral Pulmonary Lesions on Computed Tomography." In Respiratory Endoscopy, 47–52. Singapore: Springer Singapore, 2016. http://dx.doi.org/10.1007/978-981-287-916-5_8.

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Katsurada, Masahiro, and Takehiro Izumo. "The Dose and Risk Factors for Radiation Exposure from X-Ray Fluoroscopy During EBUS-GS for Peripheral Pulmonary Lesions." In Respiratory Endoscopy, 159–62. Singapore: Springer Singapore, 2016. http://dx.doi.org/10.1007/978-981-287-916-5_22.

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"Advanced Bronchoscopic Techniques for Diagnosis of Peripheral Pulmonary Lesions." In Interventional Pulmonary Medicine, 202–15. CRC Press, 2016. http://dx.doi.org/10.3109/9781420081855-16.

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"Qualitative Analysis of Peripheral Pulmonary Lesions Using Endobronchial Ultrasonography." In Endobronchial Ultrasonography, 62–72. Oxford, UK: Wiley-Blackwell, 2010. http://dx.doi.org/10.1002/9781444314366.ch7.

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Conference papers on the topic "Peripheral pulmonary lesion"

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Khomkham, Banphatree, Anan Wattanathum, and Rajalida Lipikorn. "Peripheral pulmonary lesion classification from endobronchial ultrasonography images using weight-sum of upper and lower GLCM feature." In 2017 7th IEEE International Conference on System Engineering and Technology (ICSET). IEEE, 2017. http://dx.doi.org/10.1109/icsengt.2017.8123438.

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Arimura, Ken. "Role of transbronchial needle aspiration (TBNA) during endobronchial ultrasonography with guide-sheath (EBUS-GS) for peripheral pulmonary lesion (PPL) suspected of lung cancer." In Annual Congress 2015. European Respiratory Society, 2015. http://dx.doi.org/10.1183/13993003.congress-2015.pa2987.

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Ho, E., R. J. Cho, J. Keenan, and S. Murgu. "The Feasibility of Using the "Vessel Sign" for Pre-Procedural Planning in Navigation Bronchoscopy for Peripheral Pulmonary Lesion Sampling: A Dual-Center Retrospective Study." In American Thoracic Society 2022 International Conference, May 13-18, 2022 - San Francisco, CA. American Thoracic Society, 2022. http://dx.doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a3670.

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Oki, M., H. Saka, Y. Kogure, H. Niwa, A. Yamada, A. Torii, and C. Kitagawa. "Ultrathin Bronchoscopic Cryobiopsy of Peripheral Pulmonary Lesions." In American Thoracic Society 2022 International Conference, May 13-18, 2022 - San Francisco, CA. American Thoracic Society, 2022. http://dx.doi.org/10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a3674.

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Matsumoto, Yuji, Midori Tanaka, Toshiyuki Nakai, Takaaki Tsuchida, and Yuichiro Ohe. "Cryobiopsy – a diagnostic breakthrough for peripheral pulmonary lesions -." In ERS International Congress 2019 abstracts. European Respiratory Society, 2019. http://dx.doi.org/10.1183/13993003.congress-2019.pa313.

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Okafuji, Kohei, Atsushi Kitamura, Hiroshi Nakaoka, Ryosuke Tsugitomi, Tomoyuki Tanigawa, Yutaka Tomishima, Torahiko Jinta, Naoki Nishimura, Tomohide Tamura, and Naohiko Chonabayashi. "Utility of virtual bronchoscopic navigation for peripheral pulmonary lesions." In Annual Congress 2015. European Respiratory Society, 2015. http://dx.doi.org/10.1183/13993003.congress-2015.pa2200.

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Morikawa, Kei, Hirotaka Kida, Hiroshi Handa, Naoki Furuya, Hiroki Nishine, Takeo Inoue, Hisashi Saji, Junki Koike, and Masamichi Mineshita. "The efficacy of EBUS-guided cryobiopsy for peripheral pulmonary lesions." In ERS International Congress 2020 abstracts. European Respiratory Society, 2020. http://dx.doi.org/10.1183/13993003.congress-2020.1641.

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Okafuji, Kohei, Atsushi Kitamura, Hiroshi Nakaoka, Ryosuke Tsugitomi, Tomoyuki Tanigawa, Yutaka Tomishima, Torahiko Jinta, Naoki Nishimura, Tomohide Tamura, and Naohiko Chonabayashi. "Comparison between thick and thin bronchoscopes for diagnosis of peripheral pulmonary lesions." In ERS International Congress 2016 abstracts. European Respiratory Society, 2016. http://dx.doi.org/10.1183/13993003.congress-2016.pa4676.

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Arbat, Sameer, Ashok Arbat, Swapnil Bakamwar, and Parimal Deshpande. "Role of radial EBUS cryobiopsy in peripheral pulmonary lesions: a case series." In ERS International Congress 2020 abstracts. European Respiratory Society, 2020. http://dx.doi.org/10.1183/13993003.congress-2020.2869.

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Hayama, Manabu, Takehiro Izumo, Yuji Matsumoto, Takaaki Tsuchida, Shinji Sasada, and Norio Okamoto. "Complications with endobronchial ultrasound with a guide sheath for peripheral pulmonary lesions." In Annual Congress 2015. European Respiratory Society, 2015. http://dx.doi.org/10.1183/13993003.congress-2015.pa2196.

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Reports on the topic "Peripheral pulmonary lesion"

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Zhang, Chunxi, Fangfang Xie, Runchang Li, Ningxin Cui, and Jiayuan Sun. Robotic-assisted bronchoscopy for the diagnosis of peripheral pulmonary lesions: A systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, September 2022. http://dx.doi.org/10.37766/inplasy2022.9.0115.

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Abstract:
Review question / Objective: What is the overall diagnostic yield and complication rate of robotic-assisted bronchoscopy for peripheral pulmonary lesions? Condition being studied: Many of peripheral pulmonary lesions (PPLs) may represent early-stage lung cancer. Lung cancer is the leading cause of cancer mortality globally. Early diagnosis and treatment of lung cancer are crucial for a better prognosis. With the widespread use of low-dose computed tomography (LDCT), the detection rate of PPLs is increasing. As a result, the number of PPLs requiring biopsy is progressively increasing. Transbronchial lung biopsy (TBLB) and transthoracic needle aspiration (TTNA) are the main modalities of non-surgical biopsy for PPLs. TTNA has a diagnostic yield of 90%, however, it also has a pneumothorax rate of 25%. Since TBLB avoids destroying the structure of normal pleura and lung tissue, the incidence of complications is lower. Unfortunately, traditional flexible bronchoscopy has a modest sensitivity of 34% and 63% for lesions 2 cm, respectively. The advent of guided bronchoscopy has increased the diagnostic yield to 70%. However, there is still a gap in diagnostic yield compared with TTNA. The advent of robotic-assisted bronchoscopy (RAB) is expected to further improve the diagnostic yield of TBLB for PPLs. However, the diagnostic performance of RAB for PPLs has not reached a consensus.
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