Relevant bibliographies by topics / Peripheral artery disease, resistance training, intermittent claudication

Academic literature on the topic 'Peripheral artery disease, resistance training, intermittent claudication'

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Published: 11 March 2023

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Journal articles on the topic "Peripheral artery disease, resistance training, intermittent claudication"

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Harwood, Amy E., Sean Pymer, Lee Ingle, Patrick Doherty, Ian C. Chetter, Belinda Parmenter, Christopher D. Askew, and Gary A. Tew. "Exercise training for intermittent claudication: a narrative review and summary of guidelines for practitioners." BMJ Open Sport & Exercise Medicine 6, no. 1 (November 2020): e000897. http://dx.doi.org/10.1136/bmjsem-2020-000897.

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Peripheral artery disease (PAD) is caused by atherosclerotic narrowing of the arteries supplying the lower limbs often resulting in intermittent claudication, evident as pain or cramping while walking. Supervised exercise training elicits clinically meaningful benefits in walking ability and quality of life. Walking is the modality of exercise with the strongest evidence and is recommended in several national and international guidelines. Alternate forms of exercise such as upper- or lower-body cycling may be used, if required by certain patients, although there is less evidence for these types of programmes. The evidence for progressive resistance training is growing and patients can also engage in strength-based training alongside a walking programme. For those unable to attend a supervised class (strongest evidence), home-based or ‘self-facilitated’ exercise programmes are known to improve walking distance when compared to simple advice. All exercise programmes, independent of the mode of delivery, should be progressive and individually prescribed where possible, considering disease severity, comorbidities and initial exercise capacity. All patients should aim to accumulate at least 30 min of aerobic activity, at least three times a week, for at least 3 months, ideally in the form of walking exercise to near-maximal claudication pain.
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Blears, Elizabeth E., Jessica K. Elias, Christian Tapking, Craig Porter, and Victoria G. Rontoyanni. "Supervised Resistance Training on Functional Capacity, Muscle Strength and Vascular Function in Peripheral Artery Disease: An Updated Systematic Review and Meta-Analysis." Journal of Clinical Medicine 10, no. 10 (May 19, 2021): 2193. http://dx.doi.org/10.3390/jcm10102193.

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Supervised resistance training appears to be a promising alternative exercise modality to supervised walking in patients with peripheral artery disease (PAD). This meta-analysis examined the efficacy of supervised RT for improving walking capacity, and whether adaptations occur at the vascular and/or skeletal muscle level in PAD patients. We searched Medline, CINAHL, Scopus, and Cochrane Central Register of Controlled Trials databases for randomized controlled trials (RCTs) in PAD patients testing the effects of supervised RT for ≥4 wk. on walking capacity, vascular function, and muscle strength. Pooled effect estimates were calculated and evaluated using conventional meta-analytic procedures. Six RCTs compared supervised RT to standard care. Overall, supervised RT prolonged claudication onset distance during a 6-min walk test (6-MWT) (101.7 m (59.6, 143.8), p < 0.001) and improved total walking distance during graded treadmill walking (SMD: 0.67 (0.33, 1.01), p < 0.001) and the 6-MWT (49.4 m (3.1, 95.6), p = 0.04). Five RCTS compared supervised RT and supervised intermittent walking, where the differences in functional capacity between the two exercise modalities appear to depend on the intensity of the exercise program. The insufficient evidence on the effects of RT on vascular function and muscle strength permitted only limited exploration. We conclude that RT is effective in prolonging walking performance in PAD patients. Whether RT exerts its influence on functional capacity by promoting blood flow and/or enhancing skeletal muscle strength remains unclear.
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Spannbauer, Anna, Maciej Chwała, Tomasz Ridan, Arkadiusz Berwecki, Piotr Mika, Anita Kulik, Małgorzata Berwecka, and Maria T. Szewczyk. "Intermittent Claudication in Physiotherapists’ Practice." BioMed Research International 2019 (September 18, 2019): 1–10. http://dx.doi.org/10.1155/2019/2470801.

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Intermittent claudication is a symptom of atherosclerosis of the lower limbs (peripheral arterial disease (PAD)) and is characterized by pain and cramps of lower limb muscles during exercise. Claudication leads to a reduction in physical activity of patients. PAD is a systemic disease. Atherosclerotic lesions located in the arteries of the lower limbs not only pose the risk of the ischemic limb loss, but above all, they are an important prognostic factor. Patients with claudication are at significant risk of cardiovascular complications such as infarcts or strokes. Comprehensive rehabilitation of patients with intermittent claudication based on the current TASC II (Inter-Society Consensus for the Management of Peripheral Arterial Disease) guidelines, ESC (European Society of Cardiology) guidelines, and AHA (American Heart Association) guidelines includes supervised treadmill training, training on a bicycle ergometer, Nordic Walking, resistance exercises of lower limb muscles, and exercises of upper limbs. A trained, educated, and motivated patient has a chance to improve life quality as well as life expectancy.
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Lima, Aluísio, Raphael Ritti-Dias, Cláudia L. M. Forjaz, Marilia Correia, Alessandra Miranda, Maria Brasileiro-Santos, Amilton Santos, Dario Sobral Filho, and Alexandre Silva. "A session of resistance exercise increases vasodilation in intermittent claudication patients." Applied Physiology, Nutrition, and Metabolism 40, no. 1 (January 2015): 59–64. http://dx.doi.org/10.1139/apnm-2014-0342.

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No study has shown the effects of acute resistance exercise on vasodilatory capacity of patients with peripheral artery disease. The aim of this study was to analyse the effects of a single session of resistance exercise on blood flow, reactive hyperemia, plasma nitrite, and plasma malondialdehyde in patients with peripheral artery disease. Fourteen peripheral artery disease patients underwent, in a random order, 2 experimental sessions: control (rest for 30 min) and resistance exercise (8 exercises, 2 sets of 10 repetitions at an intensity of 5–7 in the OMNI Resistance Exercise Scale). Blood flow, reactive hyperemia, plasma nitrite, and malondialdehyde were measured before and 40 min after the interventions in both sessions. Data were compared between sessions by analysis of covariance, using pre-intervention values as covariates. The increases in blood flow, reactive hyperemia, and log plasma nitrite were greater (p ≤ 0.05) after resistance exercise than the control session (3.2 ± 0.1 vs. 2.7 ± 0.1 mL·100 mL−1tissue·min−1, 8.0 ± 0.1 vs. 5.7 ± 0.1 AU, and 1.36 ± 0.01 vs. 1.26 ± 0.01 μmol∙L−1, respectively). On the other hand, malondialdehyde was similar between sessions (p > 0.05). In peripheral arterial disease patients, a single session of resistance exercise increases blood flow and reactive hyperemia, which seems to be mediated, in part, by increases in nitric oxide release.
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Wolska, Marta, Pamela Czajka, and Marek Postuła. "Intermittent claudication - the meaning of pharmacological and non-pharmacological therapy in chronic treatment." Medycyna Faktów 14, no. 3 (September 30, 2021): 240–43. http://dx.doi.org/10.24292/01.mf.0321.4.

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Intermittent claudication is a typical sign of peripheral vascular disease, which results from limited arterial blood flow due to atherosclerosis, appears during exercises and is relieved after a short break. Intermittent claudication often presents as a pain in the calf muscle after walking a particular distance. Physical examination, detailed interview and ankle–brachial index are key elements of the diagnostic process, which allows for diagnosis of peripheral artery disease. The treatment is dependent on multiple factors, including the dynamics of the disease and coexisting diseases. The aim of the treatment of patients with intermittent claudication is reducing the risk of cardiovascular complications and improving the quality of life. The treatment is based on a conservative therapy, especially march training. The pharmacological treatment is limited to a few medications, which are rarely used. In the advanced stage of the disease the most appropriate option seems surgery.
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Bronas, Ulf G., and Judith G. Regensteiner. "Connecting the past to the present: A historical review of exercise training for peripheral artery disease." Vascular Medicine 27, no. 2 (February 28, 2022): 174–85. http://dx.doi.org/10.1177/1358863x211073620.

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Peripheral artery disease (PAD), a prevalent manifestation of atherosclerosis, is associated with increased cardiovascular morbidity and mortality as well as decreased functional ability. Exercise training for PAD is acknowledged to be a highly effective treatment, which improves walking ability and cardiovascular risk. The historical development of this treatment has not been the focus of a report. Therefore, we present a historical review of research on exercise training for PAD. Overall, this body of knowledge has provided strong evidence of the efficacy of supervised exercise training (SET) to improve walking ability for patients with claudication due to PAD. SET, using intermittent bouts of walking exercise to moderate claudication pain on a treadmill, is considered the most efficacious mode of exercise to improve walking ability in patients with claudication. This compelling evidence published over the past 60 years was evaluated by the Centers for Medicare & Medicaid Services in 2017, which culminated in a national coverage determination for SET to improve symptomatic PAD. Future directions include determining optimal delivery strategies for SET and further elucidation of the mechanisms of improvement in walking ability resulting from SET. In addition, alternative forms of exercise should be evaluated and effective home- and community-based exercise interventions should be assessed. There is an enormous need to increase the inclusion of women and racial and ethnic minority groups in studies. It is to be hoped that researchers will continue with new innovative research and persistence in the treatment of claudication due to PAD.
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Gardner, Andrew W., Petar Alaupovic, Donald E. Parker, Polly S. Montgomery, Omar L. Esponda, and Ana I. Casanegra. "Influence of Peripheral Artery Disease and Statin Therapy on Apolipoprotein Profiles." International Journal of Vascular Medicine 2013 (2013): 1–7. http://dx.doi.org/10.1155/2013/548764.

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Apolipoprotein B is a stronger predictor of myocardial infarction than LDL cholesterol, and it is inversely related to physical activity and modifiable with exercise training. As such, apolipoprotein measures may be of particular relevance for subjects with PAD and claudication. We compared plasma apolipoprotein profiles in 29 subjects with peripheral artery disease (PAD) and intermittent claudication and in 39 control subjects. Furthermore, we compared the plasma apolipoprotein profiles of subjects with PAD either treated (n=17) or untreated (n=12) with statin medications. For the apolipoprotein subparticle analyses, subjects with PAD had higher age-adjusted Lp-B:C (P<0.05) and lower values of Lp-A-I:A-II (P<0.05) than controls. The PAD group taking statins had lower age-adjusted values for apoB (P<0.05), Lp-A-II:B:C:D:E (P<0.05), Lp-B:E + Lp-B:C:E (P<0.05), Lp-B:C (P<0.05), and Lp-A-I (P<0.05) than the untreated PAD group. Subjects with PAD have impaired apolipoprotein profiles than controls, characterized by Lp-B:C and Lp-A-I:A-II. Furthermore, subjects with PAD on statin medications have a more favorable risk profile, particularly noted in multiple apolipoprotein subparticles. The efficacy of statin therapy to improve cardiovascular risk appears more evident in the apolipoprotein sub-particle profile than in the more traditional lipid profile of subjects with PAD and claudication. This trial is registered with ClinicalTrials.govNCT00618670.
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Nicholson, CD. "Experimental Models of Chronic Lower Extremity Arterial Occlusive Disease: Lessons for Drug Development." Vascular Medicine 1, no. 1 (February 1996): 43–49. http://dx.doi.org/10.1177/1358863x9600100108.

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Peripheral vascular disease is the result of chronic vascular insufficiency. As the vascular insufficiency of the lower limbs progressively deteriorates, the condition progresses from intermittent claudication (pain upon exercise) to pain at rest and gangrene. In very severe cases amputation of the leg may be necessary. Whilst dieting, cessation of smoking and physical exercise all beneficially affect the progression of the disorder, the available drug therapy is of limited benefit. Very effective pharmacological agents capable of alleviating the symptoms of chronic peripheral vascular disease have not been developed. In order to mimic the vascular insufficiency of intermittent claudication, an animal model was developed in rats. This involves short-term and long-term 6–10 weeks ligation of the femoral artery of the rat. As demonstrated using measurements of hindlimb skeletal muscle, blood flow, pO2, metabolism and function, a model of intermittent claudication was produced. Using this model, the beneficial effects of physical training was demonstrated. Physical training induced an increase in blood flow and a greater capacity for aerobic metabolism in the partially ischaemic skeletal muscle. The effect of vasodilators has also been examined in this model; in contrast to agents such as Ca2+ antagonists, K+ channel openers appear to improve nutritional blood flow and metabolism in the afflicted skeletal muscle. This model can also be utilized to demonstrate the effects of haemorrheological interventions and of agents modulating muscle metabolism. However, additional effort is required to develop models for the evaluation of efficacy of antiatherothrombotic drugs.
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Kropielnicka, Katarzyna, Wioletta Dziubek, Katarzyna Bulińska, Małgorzata Stefańska, Joanna Wojcieszczyk-Latos, Ryszard Jasiński, Urszula Pilch, et al. "Influence of the Physical Training on Muscle Function and Walking Distance in Symptomatic Peripheral Arterial Disease in Elderly." BioMed Research International 2018 (September 23, 2018): 1–16. http://dx.doi.org/10.1155/2018/1937527.

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Introduction. A typical symptom of chronic lower-limb ischaemia is lower-limb pain, which occurs during walking forcing the patient to stop, intermittent claudication (IC). Exercise rehabilitation is the basic form of treatment for these patients. Aim. The aim of this study was to compare the effectiveness of three types of physical training programmes conducted over a 12-week period in patients with chronic lower-limb arterial insufficiency. Materials and Methods. Ninety-five people qualified for the 3-month supervised motor rehabilitation programme, conducted three times a week. The respondents were assigned to three types of rehabilitation programmes using a pseudo-randomization method: Group I (TW), subjects undertaking treadmill walking training; Group II (NW), subjects undertaking Nordic walking training; Group III (RES+NW), subjects undertaking resistance and Nordic walking training. Treadmill test, 6 Minute Walk Test (6MWT), and isokinetic test were repeated after 3 months of rehabilitation, which 80 people completed. Results. Combined training (RES+NW) is more effective than Nordic walking alone and supervised treadmill training alone for improving ankle force-velocity parameters (p<0.05) in patients with intermittent claudication. Each of the proposed exercise rehabilitation programmes increased walking distance of patients with intermittent claudication (p<0.05), especially in 6MWT (p=0.001). Significant relationships of force-velocity parameters are observed in the maximum distance obtained in 6MWT, both in Group III (RES + NW) and in Group II (NW) at the level of moderate and strong correlation strength, which indicates that if the lower limbs are stronger the walking distance achieved in 6MWT is longer. Conclusions. Given both the force-velocity parameters and the covered distance, the training RES + NW gives the most beneficial changes compared to training TW alone and NW alone. All types of training increased walking distance, which is an important aspect of the everyday functioning of people with IC.
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McDermott, Mary M., Philip Ades, Jack M. Guralnik, Alan Dyer, Luigi Ferrucci, Kiang Liu, Miriam Nelson, et al. "Treadmill Exercise and Resistance Training in Patients With Peripheral Arterial Disease With and Without Intermittent Claudication." JAMA 301, no. 2 (January 14, 2009): 165. http://dx.doi.org/10.1001/jama.2008.962.

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Dissertations / Theses on the topic "Peripheral artery disease, resistance training, intermittent claudication"

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Saracino, Laura. "Effects of resistance training in peripheral artery disease treatment." Doctoral thesis, 2017. http://hdl.handle.net/11562/961705.

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L’arteriopatia periferica aterosclerotica degli arti inferiori (PAD) è una patologia che colpisce circa il 20% dei soggetti al di sopra dei 70 anni. La claudicatio inter-mittens (IC), che ne è il principale sintomo, è un dolore che si presenta tipicamente ai polpacci durante il cammino. Questo sintomo limita la capacità di camminare dei pazienti influendo negativamente sul loro ruolo sociale, sul livello di attività fisica, e sulla qualità di vita. La terapia principale per l’IC è l’esercizio fisico su-pervisionato. Tuttavia se è chiaro il ruolo che quest’ultimo svolge nell’incrementare la capacità di marcia dei pazienti, non è altrettanto chiara la tipologia ottimale di esercizio da proporre. Il trattamento abitualmente utilizzato include esclusivamente cammino ed esercizi aerobici, vi sono tuttavia le basi per suppore che i pazienti potrebbero beneficiare dell’aggiunta di esercizi anaerobici di forza al loro protocollo di allenamento.
Peripheral artery disease (PAD) is a pathology of lower limbs affecting about 20% of people older than 70 years. Intermittent claudication (IC) is the most frequent symptom of PAD. IC is pain experienced during walking, typically in the calf. This limits the walking ability of patients and reduces social role, physical activity and quality of life. The main therapy for IC is supervised exercise. Whereas the primary role of supervised exercise in treatment of IC is well established there are some doubt about the best typology of exercise. Usually training includes only walking and aerobics exercises, but some elements suggested that for this patients adding strength exercises may be useful.
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Book chapters on the topic "Peripheral artery disease, resistance training, intermittent claudication"

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Thomas, Gregory S., and Myrvin H. Ellestad. "Sports Medicine and Cardiac Rehabilitation for Coronary and Peripheral Artery Disease Patients." In Ellestad's Stress Testing, edited by Gregory S. Thomas, L. Samuel Wann, and Myrvin H. Ellestad, 495–516. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190225483.003.0026.

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The chapter Sports Medicine and Cardiac Rehabilitation for Coronary and Peripheral Artery Disease (CAD) reviews the benefits and potential risks of physical activity and the opportunity for particular benefit in patients with coronary artery disease and peripheral artery disease (PAD). Longitudinal studies of large populations have found a benefit to habitual exercise on cardiovascular health, including decreasing cardiovascular mortality. A physiologic training effect is not required for benefit. Mild exercise is better than inactivity and increasing activity provides even greater benefit. Athletic training induces expected electrocardiographic changes at rest in athletes. Prescribing exercise with or without an exercise test is discussed in asymptomatic individuals as well as prior to participation in traditional cardiac rehabilitation or a supervised exercise program for patients with peripheral artery disease. PAD patients often do not have classic intermittent claudication yet are able to benefit from exercise therapy.
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