Academic literature on the topic 'Periodontitis; oral mucositis; head and neck radiotherapy'
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Journal articles on the topic "Periodontitis; oral mucositis; head and neck radiotherapy"
Khaw, Arlene, Sharon Liberali, Richard Logan, Dorothy Keefe, and P. Mark Bartold. "Influence of periodontitis on the experience of oral mucositis in cancer patients undergoing head and neck radiotherapy: a pilot study." Supportive Care in Cancer 22, no. 8 (March 20, 2014): 2119–25. http://dx.doi.org/10.1007/s00520-014-2186-3.
Full textBodard, Anne-Gaëlle, Abdelbaste Hrifach, Samuel Salino, Matthieu Fabris, Aline Desoutter, Pascal Pommier, and Jérôme Fayette. "Incidence of mucositis in patients with head and neck squamous cell carcinoma treated with radiotherapy plus cetuximab: a pilot study." Médecine Buccale Chirurgie Buccale 18, no. 3 (July 5, 2012): 181–85. http://dx.doi.org/10.1051/mbcb/2012020.
Full textLabrosse, Géraldine, Nicolas Graillon, Eric Maladiere, Romain Lan, and Fabrice Campana. "Update of photobiomodulation in oral mucositis: a systematic review." Journal of Oral Medicine and Oral Surgery 28, no. 4 (2022): 40. http://dx.doi.org/10.1051/mbcb/2022016.
Full textNicolatou-Galitis, Ourania, Konstantinos Dardoufas, Panagiotis Markoulatos, Anastasia Sotiropoulou-Lontou, Konstantinos Kyprianou, Georgia Kolitsi, George Pissakas, et al. "Oral pseudomembranous candidiasis, herpes simplex virus-1 infection, and oral mucositis in head and neck cancer patients receiving radiotherapy and granulocyte-macrophage colony-stimulating factor (GM-CSF) mouthwash." Journal of Oral Pathology & Medicine 30, no. 8 (September 2001): 471–80. http://dx.doi.org/10.1034/j.1600-0714.2001.030008471.x.
Full textBajracharya, Barsha, Subrata Bhattacharyya, and Pratibha Poudel. "Evaluation of oral mucositis in oral cancer patients undergoing radiotherapy." Journal of Chitwan Medical College 8, no. 2 (June 30, 2018): 6–9. http://dx.doi.org/10.3126/jcmc.v8i2.23730.
Full textVissink, A., J. Jansma, F. K. L. Spijkervet, F. R. Burlage, and R. P. Coppes. "Oral Sequelae of Head and Neck Radiotherapy." Critical Reviews in Oral Biology & Medicine 14, no. 3 (May 2003): 199–212. http://dx.doi.org/10.1177/154411130301400305.
Full textDewi, Tenny Setiani, Yannie Febby Lefaan, Sri Susilawati, Adji Kusumadjati, and Erry Mochamad Arief. "<strong>Correlation analysis between risk factors and mucositis oral in head and neck cancer patients undergoing radiotherapy</strong>." Padjadjaran Journal of Dentistry 34, no. 2 (July 31, 2022): 95. http://dx.doi.org/10.24198/pjd.vol34no2.39165.
Full textTraktama, Dewi Oktafia, and Irna Sufiawati. "Oral mucositis severity in patient with head and neck cancer undergoing chemotherapy and/or radiotherapy." Majalah Kedokteran Gigi Indonesia 4, no. 1 (December 19, 2018): 52. http://dx.doi.org/10.22146/majkedgiind.33709.
Full textArumsadu, Annisa Gustiasti, Niluh Ringga Woroprobosari, Rina Kartika Sari, and Rochman Mujayanto. "POTENTIAL OF OZONE WATER TO REDUCE THE SEVERITY OF ORAL MUCOSITIS IN PATIENTS POST HEAD AND NECK RADIOTHERAPY." Jurnal Medali 3, no. 1 (September 28, 2021): 12. http://dx.doi.org/10.30659/medali.v3i1.16965.
Full textVerma, Anjali, Rashmi P. John, and Kirti Srivastava. "EFFECTIVENESS OF TOPICAL APPLICATION OF MIXTURE OF HONEY AND COFFEE IN RADIATION INDUCED ORAL MUCOSITIS AMONG PATIENTS WITH HEAD & NECK CANCER UNDERGOING RADIOTHERAPY AT RADIOTHERAPY DEPARTMENT OF KGMU, LUCKNOW, U.P." International Journal of Advanced Research 8, no. 10 (October 31, 2020): 55–62. http://dx.doi.org/10.21474/ijar01/11823.
Full textDissertations / Theses on the topic "Periodontitis; oral mucositis; head and neck radiotherapy"
Chan, Sze-man, and 陳詩敏. "A clinical guideline to manage radiotherapy induced oral mucositis in head and neck cancer patients." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2010. http://hub.hku.hk/bib/B44622934.
Full textAlencar, Anelise Ribeiro Peixoto. "Tratamento da mucosite oral radio e quimioinduzida: comparação entre protocolo medicamentoso convencional e tratamentos com lasers em baixa intensidade." Universidade de São Paulo, 2011. http://www.teses.usp.br/teses/disponiveis/85/85134/tde-01072011-131133/.
Full textIn this clinical study verified the effects of low intensity laser in the prevention and treatment of oral mucositis radio and/or chemical induced. Thirty one patients with head and neck cancer were selected before being submitted to cancer exclusive radiotherapy or radio and associated chemotherapy. The patients were distributed into three randomly groups as follows: group 1- (control) conventional medicine treatment; group 2 conventional medicine treatment and daily lasertherapy as soon as grade two oral mucositis appeared; group 3 conventional medicine treatment and daily lasertherapy to be initiated immediately before radiotherapy sessions.The irradiation parameters were: wavelength of 660nm, potency of 100mW, continuous mode, punctual application, 2J energy on thirty pre-determined 30 points, with 20s of exposure per point. The control group received medical treatment which consisted in using a set of preventive and therapeutic approach for acute radiation-induced adverse effects. Results were evaluated observing occurrence and grade of oral mucositis, score of pain, loss of body mass, use of nasogastric sound line, internment and interruption of oncologic treatment due to oral mucositis. The results showed that the preventive protocol as used was the most effective in prevention and treatment of oral mucositis and that its daily application contributed in relieving the painful symptomatology so collaborating to maintain and/or bettering the life quality of oncologic patients.
Andrade, Ana Paula Eufr?zio do Nascimento. "Estudo cl?nico randomizado sobre a efic?cia da polihexanida no tratamento da mucosite oral em pacientes com c?ncer de cabe?a e pesco?o." Universidade Estadual de Feira de Santana, 2016. http://localhost:8080/tede/handle/tede/549.
Full textMade available in DSpace on 2018-01-23T22:40:06Z (GMT). No. of bitstreams: 1 ANA PAULA EUFR?ZIO.pdf: 1790027 bytes, checksum: 4b9b469a85fd902129536275d6da931f (MD5) Previous issue date: 2016-08-26
Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior - CAPES
Introduction: Malignant neoplasms represent one of the main causes of morbi-mortality in Brazil and worldwide. Radiotherapy, whether associated or not with chemotherapy, is the therapeutic modality most often used for cancer of the head and neck. However, it can trigger reactions at the oral level, such as oral mucositis, the most limiting side effect, with intense pain and difficulty eating, which may require the suspension of oncologic treatment for the patient. Polyhexanide has been used effectively and safely in the treatment of acute and chronic wounds. Objectives: To describe the clinical-epidemiologic profile and investigate the efficacy of polyhexanide in the treatment of oral mucositis and pain relief, in the period of 8-15 days, among patients with cancer of the head and neck undergoing treatment with radiotherapy (whether associated or not with chemotherapy). Methods: A randomized clinical trial was conducted, parallel and double-blind, among patients with cancer of the head and neck undergoing radiotherapy treatment with or without chemotherapy, in the High Complexity Oncology Unit of Feira de Santana, Bahia, who developed oral mucositis, were 18 years of age or older and consented to participation and signed informed consent forms in the period of July 2015 to May 2016. Two equal groups were formed by random allocation?an intervention group (polyhexanide gel) and a control group (gel without polyhexanide). These groups were reevaluated after 8 and 15 days of use of the gels. Clinical exams, evaluations of the medical records, and interviews with the application of a survey instrument used in the study were approved by the Committee for Ethics in Human Subjects Research of the State University of Feira de Santana, under the number 1.074.479/2015. Statistical analysis consisted of relative and absolute frequencies, averages, medians, and standard deviation, and the p-value?considered statistically signification when <0.05?were obtained by non-parametric Friedman tests, Wilcoxon the posts with signs and Wilcoxon-Mann-Whitney. Results: The findings were presented as an article. The mean age was 59.68 years; 58.8% men; 67.6% Brown/Black, and 79.4% with an elementary school education or less. The majority of tumors (64.7%) already presented in advanced stage, and the most frequent were those of the pharynx (23.5%) and the oral cavity (20.4%). Radiotherapy associated with chemotherapy was the most used therapy. Grades III and IV of oral mucositis were the most frequent in the third and fourth weeks of radiotherapy treatment. A total of 34 individuals were accompanied, 17 in the intervention group and 17 in the control group. After a period of 8 to 15 days, statistically significant differences were observed (p<0.05) in relation to the reduction in severity of the oral mucositis and pain, between the time points of gel use in the intervention group. Conclusions: Knowledge of the clinical-epidemiologic profile of patients undergoing oncology treatment with oral mucositis is important to establish potentially effective treatments. In this study polyhexanide represented an effective therapy in the treatment of oral mucositis and relief of pain, with positive results in the first 8 days of use.
As neoplasias malignas representam uma das principais causas de morbimortalidade no Brasil e no mundo. A Radioterapia, associada ou n?o a quimioterapia, ? a modalidade terap?utica mais empregada para o c?ncer de cabe?a e pesco?o. Todavia, pode desencadear rea??es em n?vel bucal, como a mucosite oral, o efeito mais limitante, com dor intensa e dificuldades na alimenta??o, podendo requerer at? a suspens?o do tratamento oncol?gico do paciente. A polihexanida tem sido empregada no tratamento de feridas agudas e cr?nicas, com efic?cia e seguran?a. Objetivos: Descrever o perfil cl?nico-epidemiol?gico e investigar a efic?cia da polihexanida no tratamento da mucosite oral e do al?vio da dor, no per?odo de 8 e 15 dias, em pacientes com c?ncer de cabe?a e pesco?o, sob tratamento com radioterapia associada ou n?o a quimioterapia. M?todos: Realizou-se um ensaio cl?nico randomizado, paralelo e duplo cego, com todos os pacientes com c?ncer de cabe?a e pesco?o sob tratamento com radioterapia associada ou n?o a quimioterapia, na Unidade de Alta Complexidade em Oncologia de Feira de Santana, Bahia, que desenvolveram mucosite oral, tinham 18 anos ou mais de idade e aceitaram participar assinando o termo de consentimento livre e esclarecido, no per?odo de julho de 2015 a maio de 2016. Dois grupos foram igualmente formados por aloca??o aleat?ria, o de interven??o (gel de polihexanida) e o grupo controle (gel sem polihexanida), e reavaliados nos intervalos de 8 e 15 dias de uso dos g?is. Avalia??es cl?nicas, de prontu?rios e entrevistas com aplica??o de formul?rio foram aplicadas neste estudo aprovado pelo Comit? de ?tica em Pesquisa com Seres Humanos da Universidade Estadual de Feira de Santana sob o n?mero 1.074.479/2015. Para a an?lise estat?stica empregaram-se as frequ?ncias relativas e absolutas, m?dias, medianas e desvio-padr?o, e o valor de p, considerado estatisticamente significativo quando ? 0,05 foi obtido por meio dos testes n?o param?tricos de Friedman, Wilcoxon dos postos com sinais e Wilcoxon-Mann-Whitney. Resultados: Os achados foram apresentados em forma de artigo. A m?dia de idade foi de 59,68 anos; 58,8% homens; 67,6% de cor parda e 79,4% analfabetos ou com baixo grau de escolaridade. A maioria (64,7%) dos tumores j? se apresentava em est?dio avan?ado, sendo os mais frequentes os da faringe (23,5%) e cavidade oral (20,4%). A Radioterapia associada ? quimioterapia foi a terap?utica mais empregada. Graus III e IV de mucosite oral foram mais frequentes nas 3? e 4? semanas de tratamento radioter?pico. Um total de 34 indiv?duos foi acompanhado, sendo 17 do grupo de interven??o e 17 do grupo controle. Ap?s um per?odo de 8 e 15 dias, observaram-se diferen?as estatisticamente significativas (p<0,05) em rela??o a redu??o da gravidade da mucosite oral e da dor, entre os tempos de uso do gel no grupo de interven??o. Conclus?es: O conhecimento do perfil cl?nico-epidemiol?gico de pacientes em tratamento oncol?gico com mucosite oral faz-se importante para se estabelecer terap?uticas potencialmente eficazes. Neste estudo a polihexanida apresentou-se como uma terap?utica eficaz no tratamento da mucosite oral e controle da dor, com resultados positivos ainda nos primeiros 8 dias de uso.
Lima, Aline Gouvêa de. "Avaliação da eficácia da aplicação preventiva do laser de baixa potência em pacientes com mucosite oral induzida por radioquimioterapia." Universidade de São Paulo, 2009. http://www.teses.usp.br/teses/disponiveis/5/5155/tde-23032010-100838/.
Full textPhase III, prospective, randomized, double-blind study of oral mucositis prophylaxis by low energy laser. Patients included had a diagnosis of head and neck cancer and were managed with radiochemotherapy. Arm A laser 2.5 J/cm2 daily throughout treatment and B sham laser. Inclusion of 75 patients (A/B 37/38). Grade III /IV mucositis A/B: week 2 (4/5) P=1.0, week 4 (4/12) P=0.04 and week 6 (8/9) P=1.0. Treatment breaks due to mucositis A/B 0/6 P=0.02. Severe pain A/B week 2 (5/5), week 4 (8/8) and week 6 (8/8) P=1.0. Low laser therapy was effective, delaying severe mucositis and reducing radiotherapy breaks.
Ribeiro, Sara Isabel Macedo. "Alterações na cavidade oral provocadas pelo tratamento de radioterapia em pacientes com cancro de cabeça e pescoço." Master's thesis, [s.n.], 2012. http://hdl.handle.net/10284/3702.
Full textO cancro de cabeça e pescoço representa cerca de 10% dos tumores malignos a nível mundial, e anualmente são diagnosticados sensivelmente 500.000 novos casos em todo o mundo. A nível nacional, o cancro de cabeça e pescoço é uma neoplasia maligna relativamente frequente, sendo responsável por uma taxa de mortalidade elevada. No ano de 2005 e 2006 foram registados 10286 doentes no RORENO, e destes, 1240 eram referentes à cavidade oral e pescoço, sendo as principais localizações na glândula tiroideia, seguida da laringe, esófago, boca (que inclui a gengiva, o pavimento da boca, palato e o trígono retromolar), língua, amígdala, lábio, hipofaringe, nasofaringe, orofaringe e glândulas salivares. Não só o cancro oral produz alterações na cavidade oral, bem como a terapia utilizada para o tratamento dos diversos tipos de neoplasias. A radioterapia é uma das formas terapêuticas utilizada para o tratamento das neoplasias da cabeça e pescoço, porém apesar da sua eficácia esta modalidade terapêutica também promove alguns efeitos adversos, tais como a mucosite, xerostomia, dermatite, disfagia, disgeusia, infecções secundárias, cárie por radiação, trismo, necrose de tecido mole e osteorradionecrose. Estes efeitos colaterais decorrentes da radioterapia estão relacionados com a dose de radiação, a forma de administração, a extensão e a localização da área a ser irradiada, bem como a qualidade e poder de penetração da radiação e dos factores individuais do paciente. Deste modo, os danos da radiação podem manifestar-se gradualmente ao longo de muitos meses ou anos após o terminar do tratamento e/ou ocorrer meses depois do termino da terapia antitumoral. As complicações do cancro de cabeça e pescoço encontram-se entre as mais devastadoras a curto e a longo prazo, por afectarem as actividades humanas mais básicas, tais como alimentar-se e comunicar-se. Assim, é de grande importância que o Médico Dentista, a fim de minimizar os transtornos decorrentes da terapia antitumoral, examine o paciente antes de iniciar o tratamento antineoplásico, e inicie um programa de higiene oral e seja instruído sobre a importância desta higienização no decurso do tratamento oncológico. Assim sendo, é necessário uma equipa multidisciplinar, do qual o Médico Dentista faça parte, de modo a tornar mais digna a vida dos pacientes com este tipo de patologia, ou mesmo prevenir tais complicações surgidas devido à terapêutica. The head and neck cancer represents about 10% of malignant tumors worldwide, and are diagnosed annually substantially 500,000 new cases worldwide. Nationally, the head and neck cancer is a relatively common malignancy, accounting for a high mortality rate. In 2005 and 2006 were 10286 registered patients in RORENO, and of these, 1240 were related to the oral cavity and neck, and the main locations in the thyroid gland, followed by the larynx, esophagus, mouth (including gum, floor of mouth, palate and retromolar trigone), tongue, tonsil, lip, hypopharynx, nasopharynx, oropharynx and salivary glands. Not only oral cancer produces changes in the oral cavity as well as the therapy used for treating various types of neoplasms. Radiation therapy is one way used for the therapeutic treatment of cancers of head and neck, but despite its efficacy, this type of treatment also promotes some adverse effects, such as mucositis, xerostomia, dermatitis, dysphagia, dysgeusia, secondary infections, caries by radiation, trismus, soft tissue necrosis and osteoradionecrosis. These side effects resulting from radiotherapy are related to the radiation dose, the administration form, the extent and location of the area to be irradiated, and the quality and and the penetrating power of the radiation and the individual factors of the patient. This way, the radiation damage may occur gradually over many months or years after the end of the treatment and / or occur months after the end of antitumor therapy. Complications of head and neck cancers are among the most devastating in the short and long term, to affect the most basic human activities such as eating and communicating. Thus, it is very important that the dentist, in order to minimize the problems caused antitumor therapy, examine the patient before starting their treatment, and initiate a program of oral hygiene and instructed on the importance of hygiene during the cancer treatment. Therefore, it is necessary a multidisciplinary team, of which the dentist is an essential part, to make more worthy the life of patients with this type of pathology, or even prevent such complications arising due to therapy.
Carvalho, Filipa Baptista Neto Viegas de. "A terapêutica fotodinâmica nos tratamentos das lesões potencialmente malignas e cancro da cavidade oral." Master's thesis, [s.n.], 2015. http://hdl.handle.net/10284/5239.
Full textA terapia fotodinâmica (PDT, do inglês, photodynamic therapy) é uma opção terapêutica recente e valiosa, dirigida para a destruição das células tumorais, com potencial para ser incluída no tratamento principal de combate ao cancro, bem como adjuvante de outras terapêuticas. Atualmente é considerada uma estratégia terapêutica de sucesso, clinicamente, aprovada para o tratamento de lesões potencialmente malignas (LPM) e malignas da cavidade oral. A PDT envolve a administração de um fotossensibilizador (PS, do inglês, photosensitizer) que, por si só, não possui efeito farmacológico. Contudo, este é, posteriormente ativado por irradiação, com luz visível de comprimento de onda (λ) adequado ao local a tratar. Com a foto-ativação do PS ocorre a produção de espécies reativas de oxigénio (ROS, do inglês, reactive oxygen species) que dão inicio à morte celular. O processo está associado com a indução de uma forte reação inflamatória local, potenciando a resposta imunitária e conduzindo à destruição efetiva das células tumorais. O efeito citotóxico ocorre, apenas, no local de ativação da luz e o PS acumula-se preferencialmente nas células malignas, pelo que esta terapêutica apresenta elevada seletividade e um baixo número de efeitos secundários. No contexto clínico, a PDT é utilizada em diversas áreas da medicina como a oftalmologia, a dermatologia e a oncologia, entre outras. No entanto, a sua utilização no tratamento do cancro ainda é limitada.
Photodynamic therapy (PDT) is a new and valuable therapeutic option, directed to the destruction of tumor cells, with the potential to be included in the primary treatment to combat cancer, as well as an adjunct to other therapies. A successful therapeutic strategy, clinically approved for the treatment of premalignant lesions (LPM) and malignant oral cavity is considered currently. PDT involves the administration of a photosensitizer (PS) which, by itself, does not possess pharmacological effect. However, this is subsequently activated by irradiation with visible light of wavelength (λ) appropriate to the site to be treated. With the photo-activation of the PS occurs the production of reactive oxygen species (ROS, English, reactive oxygen species) that give beginning to cell death. The process is associated with the induction of a strong local inflammatory response, enhancing the immune response and leading to the effective destruction of tumor cells. The cytotoxic effect occurs only in the light activation site and the PS accumulates preferentially in malignant cells, whereby this treatment has high selectivity and a low number of side effects. In the clinical context, PDT is used in many areas of medicine such as ophthalmology, dermatology and oncology, among others. However, their use in cancer treatment is still limited.
Khaw, Arlene Bee Hong. "Influence of periodontitis on the experience of oral mucositis in cancer patients undergoing head and neck radiotherapy." Thesis, 2014. http://hdl.handle.net/2440/83794.
Full textThesis (D.Clin.Dent.) -- University of Adelaide, School of Dentistry, 2014
Bowen, Joanne. "Prevention of oral mucositis in head and neck cancer patients : a systematic review." Thesis, 2012. http://hdl.handle.net/2440/78862.
Full textThesis (M.Phil.) -- University of Adelaide, The Joanna Briggs Institute, 2012
Huang, Yi Ying, and 黃怡螢. "Impact of Oral Care on Oral Mucositis and Quality of Life for Head and Neck Cancer Patients during Radiotherapy." Thesis, 2013. http://ndltd.ncl.edu.tw/handle/e4sa4b.
Full textAl-Qadami, Ghanyah Hamid Hussein. "Exploring the Role of the Gut Microbiome in Toxicity and Response to Radiotherapy for Head and Neck Cancer." Thesis, 2021. https://hdl.handle.net/2440/135226.
Full textThesis (Ph.D.) -- University of Adelaide, School of Biomedicine, 2021
Conference papers on the topic "Periodontitis; oral mucositis; head and neck radiotherapy"
Gu, Fangyi, William D. Duncan, YingDong Feng, Austin Miller, Nicolas Schlecht, Alan Hutson, and Anurag K. Singh. "Abstract 4860: Association between timing of radiotherapy and severity of oral mucositis in head-neck cancer patients." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.sabcs18-4860.
Full textGu, Fangyi, William D. Duncan, YingDong Feng, Austin Miller, Nicolas Schlecht, Alan Hutson, and Anurag K. Singh. "Abstract 4860: Association between timing of radiotherapy and severity of oral mucositis in head-neck cancer patients." In Proceedings: AACR Annual Meeting 2019; March 29-April 3, 2019; Atlanta, GA. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1538-7445.am2019-4860.
Full textLin, Hongying, Min Ma, and Shengcun Zhang. "The Clinical Analysis on Acute Oral Cavity Mucositis Caused by the Radiotherapy for the Head and Neck Cancer." In 2015 International Forum on Bioinformatics and Medical Engineering. Paris, France: Atlantis Press, 2015. http://dx.doi.org/10.2991/bme-15.2015.5.
Full textHahn Kakas Galassi, Victória, MARY ANN FOGLIO, Michelle P. Jorge, Ilza M. O. Souza, Nubia Cassia Queiroz, and CARMEN S. P. LIMA. "Evaluation of life quality in pacients with head and neck squamous cells carcinome before and after the appereance of Oral Mucositis (OM) caused by chemiotherapy treatment with Cisplatin associated with Radiotherapy: Relation of the Presence and Level of OM in second phase clinical study comparing the treatment of OM between a phytotherapic and application of low intensity laser." In XXV Congresso de Iniciação Cientifica da Unicamp. Campinas - SP, Brazil: Galoa, 2017. http://dx.doi.org/10.19146/pibic-2017-78218.
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