Academic literature on the topic 'Periocular skin cancer'

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Journal articles on the topic "Periocular skin cancer"

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Moran, Joshua M., and Paul O. Phelps. "Periocular skin cancer: Diagnosis and management." Disease-a-Month 66, no. 10 (October 2020): 101046. http://dx.doi.org/10.1016/j.disamonth.2020.101046.

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Perry, Julian D., Sara C. Polito, Rao V. Chundury, Arun D. Singh, Michael A. Fritz, Allison T. Vidimos, Brian R. Gastman, and Shlomo A. Koyfman. "Periocular Skin Cancer in Solid Organ Transplant Recipients." Ophthalmology 123, no. 1 (January 2016): 203–8. http://dx.doi.org/10.1016/j.ophtha.2015.09.030.

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Carniciu, Anaïs L., Nina Jovanovic, and Alon Kahana. "Eyelid Complications Associated with Surgery for Periocular Cutaneous Malignancies." Facial Plastic Surgery 36, no. 02 (April 2020): 166–75. http://dx.doi.org/10.1055/s-0040-1709515.

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AbstractPeriocular skin is highly prone to malignancies, especially basal cell and squamous cell carcinomas. Because of the complex anatomy and eye-protecting functions of the periocular tissues, treatment of these cancers requires special considerations. Mohs micrographic surgery is usually the treatment of choice, whenever possible, in order to enhance margin control while limiting collateral damage to nearby normal structures. Cancer excision, whether by Mohs or other techniques, will leave a complex defect that requires careful anatomical and functional reconstruction. This study presents some of the challenges of treating periocular skin cancer and associated reconstructive surgery and provides an intellectual framework for addressing these challenges. The key topics are adherence to anatomical landmarks and aesthetic units, proper distribution of tension, and matching the correct reconstructive approach, that is, type of flap or graft, to the defect at hand. This review is not meant to be exhaustive, but it will provide both basic and advanced considerations.
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Ault, Alicia. "BCC Is Most Common Form Of Periocular Skin Cancer." Skin & Allergy News 40, no. 7 (July 2009): 18–19. http://dx.doi.org/10.1016/s0037-6337(09)70321-3.

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Turkmen, Arif, Metin Temel, Ayla Gokce, and Mehmet Bekerecioglu. "Orbital exenteration for the treatment of advanced periocular skin cancer." European Journal of Plastic Surgery 36, no. 2 (September 9, 2012): 69–74. http://dx.doi.org/10.1007/s00238-012-0759-2.

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Scofield-Kaplan, Stacy M., Colette Jackson, Troy Gurney, Emma McDonnell, and Ronald Mancini. "Predictive Value of Preoperative Periocular Skin Cancer Measurements for Final Mohs Defect Size." Ophthalmic Plastic and Reconstructive Surgery 35, no. 6 (2019): 604–8. http://dx.doi.org/10.1097/iop.0000000000001421.

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Patel, Sagar, and Kamel Itani. "Review of Eyelid Reconstruction Techniques after Mohs Surgery." Seminars in Plastic Surgery 32, no. 02 (May 2018): 095–102. http://dx.doi.org/10.1055/s-0038-1642058.

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AbstractMohs micrographic surgery achieves high cure rates while preserving healthy tissue making it the optimal treatment for skin cancer. The goals of eyelid reconstruction after Mohs surgery include restoring eyelid structure and function while attaining acceptable aesthetic results. Given the variety of eyelid defects encountered after Mohs surgery, a thorough understanding of the complex eyelid anatomy as well as an in-depth knowledge of the numerous reconstructive techniques available are required to accomplish these reconstructive goals. In this article, the authors review eyelid anatomy and discuss a variety of techniques used for the reconstruction of defects involving the periocular region.
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Prídavková, Zuzana, Anna Bieliková, Nina Ferková, and Daryna Lysková. "Recurrent Periocular Basal Cell Carcinoma. Case Report." Czech and Slovak Ophthalmology 77, no. 4 (August 15, 2021): 208–13. http://dx.doi.org/10.31348/2021/24.

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Aim: We present the management of a severe case of recurrent periocular basal cell carcinoma, orbital invasion and exenteration. Case report: The present case is of a recurrent basal cell carcinoma in a 84-year-old male presenting with non-healing lesion above right eyelid. A tumor excision was performed in May 2014. Histopathology revealed a basal cell carcinoma (dg. C44.1 ICD-10-CM) with positive margins. The re-excision of the lesion was performed. After two years, there was a local recurrence and orbital invasion. Indication for external curative radiation therapy. Plastic surgery of the upper eyelid. Orbital exenteration was indicated in January 2018. After another year, a recurrence of the tumor was once again noted. Histopathology revealed a basal cell carcinoma (dg. C44.1 (TNM 7, pMx, pNx, pTx)). The patient was indicated for external radiotherapy. There were no indications for biological treatment. After another year, a progression of the local finding was noted. Conclusion: Basal cell carcinoma (BCC) is the most common non-melanoma skin cancer of the periocular region. Primary treatment of basal cell carcinoma is surgical. Advanced lesions require extensive surgical interventions and other available treatment modalities. In some cases, mutilating surgery – exenteration of the orbit is inevitable. Despite a relatively small percentage of invasive diseases today, advanced stages may still occur; either as a result of the patient's late presentation, inadequate initial therapy aimed at maintaining critical periorbital structures, or due to high tumor aggression. The case report highlights necessity of radical resection of primary tumor with histological examination.
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Martel, Arnaud, Sandra Lassalle, Alexandra Picard-Gauci, Lauris Gastaud, Henri Montaudie, Corine Bertolotto, Sacha Nahon-Esteve, Gilles Poissonnet, Paul Hofman, and Stephanie Baillif. "New Targeted Therapies and Immunotherapies for Locally Advanced Periocular Malignant Tumours: Towards a New ‘Eye-Sparing’ Paradigm?" Cancers 13, no. 11 (June 5, 2021): 2822. http://dx.doi.org/10.3390/cancers13112822.

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The management of periocular skin malignant tumours is challenging. Surgery remains the mainstay of treatment for localised eyelid cancers. For more locally advanced cancers, especially those invading the orbit, orbital exenteration has long been considered the gold standard; however, it is a highly disfiguring and traumatic surgery. The last two decades have been marked by the emergence of a new paradigm shift towards the use of ‘eye-sparing’ strategies. In the early 2000s, the first step consisted of performing wide conservative eyelid and orbital excisions. Multiple flaps and grafts were needed, as well as adjuvant radiotherapy in selected cases. Although being incredibly attractive, several limitations such as the inability to treat the more posteriorly located orbital lesions, as well as unbearable diplopia, eye pain and even secondary eye loss were identified. Therefore, surgeons should distinguish ‘eye-sparing’ from ‘sight-sparing’ strategies. The second step emerged over the last decade and was based on the development of targeted therapies and immunotherapies. Their advantages include their potential ability to treat almost all tumours, regardless of their locations, without performing complex surgeries. However, several limitations have been reported, including their side effects, the appearance of primary or secondary resistances, their price and the lack of consensus on treatment regimen and exact duration. The aim of this article was to review the evolution of the management of locally advanced periocular malignant tumours over the last three decades and highlight the new paradigm shift towards the use of ‘eye-sparing’ strategies.
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Kovacevic, Predrag T., Milan M. Visnjic, Tatjana T. Kovacevic, Milan R. Radojkovic, and Mariola R. Stojanovic. "Extended orbital exenteration in the treatment of advanced periocular skin cancer with primary reconstruction with a galeacutaneous flap." Scandinavian Journal of Plastic and Reconstructive Surgery and Hand Surgery 43, no. 6 (January 2009): 325–29. http://dx.doi.org/10.1080/02844310903138963.

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Dissertations / Theses on the topic "Periocular skin cancer"

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Sun, Michelle Tian. "Periocular malignancy and eyelid reconstruction." Thesis, 2017. http://hdl.handle.net/2440/106326.

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Non-melanoma skin cancer is the most common cancer in Australia. Basal cell carcinoma and squamous cell carcinoma are the two most frequently encountered types of non-melanoma skin cancer, and together they make up over 90% of all skin cancers. The periocular region is involved in 10% of cases and is associated with significantly more disease-related morbidity due to the local effect of both the disease and the surgical treatment on ocular adnexa. Therefore, it is imperative that high-risk tumours are correctly identified to ensure appropriate management and surveillance. Surgical excision remains the gold standard treatment but functional reconstruction of the eyelid represents an ongoing challenge. Despite the wide range of autologous and artificial eyelid substitutes, there is yet to be an ideal replacement for the specialised eyelid tissue called the tarsus. The tarsus is responsible for both structural support and physical form, making its adequate substitution fundamental to functional outcomes. Numerable uncertainties remain regarding the staging and management of periocular non-melanoma skin cancer which, combined with our lack of ideal eyelid tarsus substitutes, represents the basis for work undertaken as part of this thesis. Previous studies contributing to our knowledge of periocular basal cell carcinoma histological subtypes and treatment of invasive disease are first reviewed in Chapter 2. Chapter 3 subsequently summarises our understanding of periocular squamous cell carcinoma with a particular focus on the utilisation and prognostic role of the most up-to-date American Joint Committee on Cancer (AJCC) staging system for the eyelid carcinoma. In order to determine the required properties for the ideal tarsus tissue substitute, Chapter 4 analyses the normal biomechanical properties of the eyelid tarsus tissue. This study, the first of its kind for human tarsus tissue, provides a benchmark for bioengineering studies described in the following chapter. In Chapter 5, we describe the development of a novel bioengineered three-dimensional scaffold which is tailor-made to behave biomechanically like natural tarsus. In order to improve in vivo compatibility, we also successfully cultured fibroblasts from eyelid skin samples which were then seeded onto our bioengineered scaffolds, the results of which are described in Chapter 6. Finally, insights into the presentation, staging and management of periocular basal cell carcinoma and squamous cell carcinoma, along with our novel bioengineered eyelid tarsus substitute are placed in the context of the previous literature in Chapter 7, before possible directions for future studies are discussed in Chapter 8.
Thesis (Ph.D.) -- University of Adelaide, Adelaide Medical School, 2017.
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Book chapters on the topic "Periocular skin cancer"

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Doanh, Le Huu, Nguyen Van Thuong, and Michael Tirant. "Periocular Squamous Cell Carcinoma in a Child with Xeroderma Pigmentosum." In Clinical Cases in Pediatric Skin Cancers, 123–27. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-93666-2_27.

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Kersten, Robert C. "Management of Periocular Neoplasms." In Surgery of the Eyelid, Lacrimal System, and Orbit. Oxford University Press, 2011. http://dx.doi.org/10.1093/oso/9780195340211.003.0007.

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Epithelial malignancy of the eyelid is a common problem, representing about 14% of skin cancers in the head and neck region. The goals when treating any skin cancer are complete elimination of the tumor and minimal sacrifice of normal adjacent tissues. These concepts are of paramount importance when treating periocular epithelial malignancies because of the complex nature of the periocular tissues and their critical function in protecting the underlying globe, as well as the increased risk that recurrent tumor in this area poses. Many modalities have been advocated, by a variety of medical practitioners, for the treatment of epithelial malignancies in the periocular region. There are two key considerations in selecting a treatment for skin cancers. The first is that the selected modality must be capable of eradicating all tumor cells to which it is applied. The second is that some mechanism must exist to ensure that it is applied to all the existing tumor cells. Because tumors of the lid margins and canthi often exhibit slender strands and shoots of cancer cells that may infiltrate beyond the clinically apparent borders of the neoplasm, appropriate monitoring to ensure that the treatment modality reaches all of the cancer cells is essential. Numerous studies have demonstrated that clinical judgment of tumor margins is inadequate, significantly underestimating the area of microscopic tumor involvement. The introduction of frozen-section control to document adequacy of tumor excision marked a major advancement in the treatment of eyelid malignancies and now represents the standard of care. Any treatment modality that does not use microscopic monitoring of tumor margins must instead encompass a wider area of adjacent normal tissue in hopes that any microscopic extensions of tumor will fall within this area. The purpose of this chapter is to explore alternative methods of periocular cancer treatment. Mohs micrographic technique is a refinement of frozen-section control of tumor borders that, by mapping tumor planes, allows a three-dimensional evaluation of tumor margins rather than the two-dimensional examination provided by routine frozen section. The modality was initiated by Frederick E. Mohs, MD, in 1936.
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