Dissertations / Theses on the topic 'Perimenopause'
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McChlery, Sheena Maureen. "Women’s experiences of perimenopause." Thesis, McChlery, Sheena Maureen (2021) Women’s experiences of perimenopause. PhD thesis, Murdoch University, 2021. https://researchrepository.murdoch.edu.au/id/eprint/62728/.
Full textMosconi, Lisa, Valentina Berti, Crystal Guyara-Quinn, Pauline McHugh, Gabriella Petrongolo, Ricardo S. Osorio, Christopher Connaughty, et al. "Perimenopause and emergence of an Alzheimer’s bioenergetic phenotype in brain and periphery." PUBLIC LIBRARY SCIENCE, 2017. http://hdl.handle.net/10150/626072.
Full textPortella, Caio Fábio Schlechta. "Qualidade de vida e insônia na perimenopausa: meditação como estratégia de intervenção." Universidade de São Paulo, 2014. http://www.teses.usp.br/teses/disponiveis/6/6136/tde-09042014-104755/.
Full textIntroduction: Insomnia is one of the most common disorders that affect the population in contemporaneity, because of important hormonal and psychosocial changes is very prevalent in perimenopause. There is a still understudied relationship between sleep efficiency and meditative practice. The treatments for insomnia are usually expensive and palliative. Objective: Evaluate the effects of meditation in insomnia (caused by typical symptoms of perimenopause) and quality of life in this phase of life. Method: controlled clinical trial to evaluate the effects of meditation in women with insomnia during perimenopause and impact on quality of life in 8-week intervention. The study was conducted from April to July 2013 with 33 perimenopausal women aged between 40-55 years in 3 units of public organization in São Paulo, SP, Brazil. The participants were randomly assigned to two groups, one who performed only Sleep Hygiene-HS (n = 15) and another who performed Meditation + Sleep Hygiene - SH + M (n = 18). Weekly meetings were held with the participants of both groups to practice meditation in a group and / or criteria for the sleep hygiene. The M + SH group also performed daily meditation practice. To assess the statistical significance of differences in means before and after the interventions in each group, the Wilcoxon test was applied. Results: Improvement of sleep quality in both groups, however comparing the differences in the scores of the Insomnia Severity Index between groups, group M + SH had a greater effect on both measures compared to the SH group. In M + SH group showed a statistically significant reduction in the categories of the Kupperman Menopausal Index: palpitations, paresthesia and Total Score, already in the SH group there was no significant reduction in any parameter of the Kupperman Index. A Significant improvement in overall quality of life (measured by WHOQOL-brief) score in group M + HS, and HS group had improvement in social relationships domain. Conclusion: The results suggest that meditation can be useful tool in the treatment of primary insomnia during the perimenopause. The quality of life during this period is also favored globally by daily meditation practice.
Freire, Neto Francisco Paulo. "Influ?ncia do tratamento com ?cido lipoico sobre o metabolismo ?sseo e perfil antioxidante de mulheres na perimenopausa." Universidade Federal do Rio Grande do Norte, 2010. http://repositorio.ufrn.br:8080/jspui/handle/123456789/13472.
Full textBone is a dynamic tissue that is in constant process of remodeling in response to mechanical stress and hormonal changes. This study aimed to understand the relationship between the biochemical changes, which women in the menopausal transition are subject to, and how the use of an alternative therapy with lipoic acid (LA) could influence these changes. The study of double-blind, was carried out in perimenopausal women that underwent a three month treatment with 600 mg of AL compared with another group that received placebo during the same period. This study showed that women had a waist circunference and body mass index above the values recommended by WHO (WC ≥ 80 cm; BMI > 25kg/m2). Associated with this, these women had increased concentrations of total cholesterol and triglycerides, and borderline LDL (Total Cholesterol > 200mg/dL; Triglycerides > 150mg/dL; LDL >130mg/dL). These changes were not affected by treatment with AL. There were no shifts in liver profile (ALT, AST and GGT), kidney profile (urea, creatinine, total protein and albumin), mineral profile (Total Calcium, Ionized Calcium, Phosphorus and Magnesium) as well in bone markers (osteocalcin, Total Alkaline Phosphatase and Tartrate Resistant Acid Phosphatase) after treatment with LA. The results of the oxidative profile showed that treatment with LA decreased GPx activity (p < 0,01), while for the TBARS, GSH and SOD activity there were no differences. With regard to SOD, this enzyme will submit to be high in the placebo group after 3 months of study (p<0,05). The expression of RANKL mRNA was reduced (p < 0,05) and of RANK increased (p <0.001), after treatment with LA, while the expression of IL-6 and TNF-ɑ genes were no changed. We conclude that women already in the perimenopause stage have changes in lipid profile and body composition that could induce shifts in oxidative and bone metabolism. However, LA treatment has provided an effective effect in the oxidative and bone profile since the earliest markers such as GPx activity and mRNA expression of RANKL, respectively, were reduced associated with no change in SOD activity. These results suggest a beneficial and protective effect of LA, indicating it potential as an alternative treatment to help the to prevent the complications associated with estrogen deficiency
O osso ? um tecido din?mico que est? em constante processo de remodela??o em resposta ao estresse mec?nico e mudan?as hormonais. O presente trabalho teve por objetivo entender a rela??o entre as altera??es bioqu?micas, oxidativas e moleculares em mulheres em transi??o menopausal e a influ?ncia do uso do ?cido lipoico (AL) nessas altera??es. O estudo do tipo duplo-cego, foi realizado com mulheres em perimenopausa submetidas ? um tratamento de 3 meses com 600 mg de AL administrados por via oral em duas doses di?rias, comparadas com um outro grupo que recebeu placebo durante o mesmo per?odo. O presente trabalho mostrou que as mulheres apresentaram uma circunfer?ncia de cintura (CC) e um ?ndice de massa corporal, em m?dia, acima dos valores preconizados pela OMS (CC ≥ 80 cm; IMC > 25kg/m2). Al?m disso, essas mulheres apresentaram aumento nas concentra??es de colesterol total e triglicer?deos, al?m de valores de LDL pr?ximos do lim?trofe (Colesterol Total > 200mg/dL; Triglicer?deos > 150mg/dL; LDL >130mg/dL). Essas altera??es n?o sofreram influ?ncia do tratamento com AL. N?o foram encontradas altera??es no perfil hep?tico (ALT, AST e GGT) e renal (Ur?ia, Creatinina, Prote?nas Totais e Albumina) das mulheres ap?s o tratamento com AL, bem como no perfil mineral (C?lcio Total, C?lcio Ionizado, F?sforo e Magn?sio) e ?sseo (Osteocalcina, Fosfatase Alcalina Total e Fosfatase ?cida Tartarato Resistente). Os resultados do perfil oxidativo mostraram que o tratamento com AL diminuiu a atividade da enzim?tica da Glutationa Peroxidase (GPx) (p <0,01), enquanto para os par?metros Subst?ncias Reativas ao ?cido Tiobarbit?ricos (SRAT s), Glutationa Reduzida (GSH) e Super?xido Dismutase (SOD) n?o houve diferen?as. A SOD apesentou-se elevada no grupo placebo ap?s os 3 meses de estudo (p<0,05). A express?o do mRNA do RANKL em leuc?citos totais mostrou-se diminu?da (p < 0,05) e do RANK aumentada (p<0,001), ap?s o tratamento com AL, enquanto a express?o dos genes IL-6 e TNF-ɑ n?o apresentou altera??o. Podemos concluir que as mulheres em est?gio de perimenopausa, inicial de defici?ncia estrog?nica, apresentam altera??o no perfil lip?dico e composi??o corporal, e que essas altera??es poderiam estar induzindo altera??es no perfil oxidativo e do metabolismo ?sseo. Entretanto, o tratamento com AL se mostrou eficaz para o perfil oxidativo, bem como ?sseo j? que marcadores precoces como a atividade da GPx e a express?o do mRNA do RANKL, respectivamente, foram reduzidos associada a n?o altera??o na atividade da SOD. Estes resultados sugerem o efeito ben?fico e protetor do AL, indicando-o como uma alternativa para tratamento auxiliar nas complica??es associadas ? defici?ncia estrog?nica
Morgan, Patricia Ann. "Women's perceptions of midlife mothering during perimenopause : the impact on health and well-being through life's transitions." Thesis, Swansea University, 2010. https://cronfa.swan.ac.uk/Record/cronfa42771.
Full textOliveira, Nayara Pestana de. "Efeitos da terapia estrogênica sobre a neuroquímica de fêmeas em modelo animal de perimenopausa (rata) induzida pelo 4-diepóxido de vinilciclohexano." Universidade de São Paulo, 2018. http://www.teses.usp.br/teses/disponiveis/17/17134/tde-23072018-104343/.
Full textPerimenopause represents the transition from reproductive to non-reproductive life. It is usually characterized by neuroendocrine, metabolic and behavioural changes, which result from a follicular depletion and reduced number of ovarian follicles. During this period, women are more likely to express mood disorders and anxiety. The exposure of animals to diepoxide 4-vinylcyclohexene (VCD) is a well-established experimental model for perimenopause studies, as VCD induces loss of ovarian small follicles (primary and primordial) in mice and rats by accelerating the natural process of atresia. Although estrogens levels are normal or even high during perimenopause, estrogen therapy can be beneficial for symptomatic perimenopausal women. The aim of this study was to investigate whether gradual follicular depletion induced by VCD results in changes in the neurochemistry of female rats in brain nuclei that control mood and the role of estradiol on these changes. Female rats (28 days) were daily injected with VCD or corn oil (O) for 15 days. Around 55 days after the first injection, pellets of 17?-estradiol (E) or O were inserted s.c (Groups O+O; VCD+O; VCD+E). Around 21 days after, rats O+O and VCD+O were decapitated between 0900 h and 1100 of diestrus while rats VCD+E were decapitated exactly 21 days after the onset of E therapy. Another set of rats followed the same experimental design and were perfused for TH and TPH immunohistochemistry in Locus coeruleus (LC) and Dorsal Raphe Nuclei (DRN), respectively. Blood was collected for estradiol and progesterone measurement by radioimmunoassay (RIA). The brains were removed from decapitated rats to punch out LC, DRN, hippocampus and amygdala to analyse the expression of mRNA for ER? and PR by RT/PCR. This experiment was replicated to punch out the hippocampus and amygdala for the determination of noradrenaline (NE) and serotonin (5-HT) contents by High Performance Liquid Chromatography, followed by Electrochemical Detection (HPLC/ED). As expected, plasma concentrations of estradiol were not different from those of control rats (O + O). Plasma concentrations of progesterone in the periestropause were lower than those in the control group, which was reversed by estradiol. In the LC, the PR expression in the periestropause was similar to that of the control rats, whereas the ER? expression was lower; estradiol therapy did not modify the expression of any of these receptors. The12 density of noradrenergic (TH +) neurons in LC was not altered by either follicular depletion or estrogen therapy. In periestropause, NA content was lower in the amygdala, but not in the hippocampus, and estradiol did not alter this content in any of the areas. In NDR, the expression of PR and ER? in periestropausal rats was lower than in controls; estradiol prevented the decrease of ER? expression, but not PR. The NDR was analyzed separately for the entire rostrocaudal axis in three anatomical levels: rostral, middle and caudal, each divided into three sub-regions: lateral, dorsal and ventral. The number of serotonergic neurons (TPH +) in NDR was lower in the periestropause, and estradiol was able to reverse this effect, acting mainly in the caudal region. PR gene expression was not altered by either follicular depletion or estrogen therapy in either the amygdala or the hippocampus. ER? expression was also no different in periestropause compared to the control group, but estradiol increased this expression in the hippocampus. Both in the amygdala and in the hippocampus there was a reduction in 5-HT content in the periestropause, and estradiol was able to reestablish the levels of this neurotransmitter at the control values only in the hippocampus. These data elucidate, at least in part, the mechanisms of the positive effect of estrogen therapy on the symptoms of normoestrogenic women in perimenopause. These effects do not appear to significantly involve the central noradrenergic system but result from increased peripheral progesterone biosynthesis in association with positive regulation of ER? in the NDR and hippocampus, which appears to potentiate the serotonergic NDR/HPC pathway. Therefore, the development of new therapies that activate ER? may be an alternative to obtain the positive effects of the estradiol action, eliminating the side effects of the estradiol therapies that normally result from the activation of ER?.
Olson, Ann Colleen Falkenberg. "Perimenopausal Women's Intended and Actual Behavioral Response to Bone Health Interventions." Diss., The University of Arizona, 2008. http://hdl.handle.net/10150/194232.
Full textKist, William B. "The effect of a brief period of low-fat and low-carbohydrate diet on postprandial lipemia, caloric intake, and mood in normal weight and overweight/obese premenopausal women /." free to MU campus, to others for purchase, 2002. http://wwwlib.umi.com/cr/mo/fullcit?p3074416.
Full textMatos, Gabrielle Silveira Rocha. "Est?gio menopausal e n?veis hormonais no desempenho muscular e funcional em mulheres de meia idade: um estudo transversal." Universidade Federal do Rio Grande do Norte, 2014. http://repositorio.ufrn.br:8080/jspui/handle/123456789/16751.
Full textIntroduction: Hypoestrogenism is the main characteristic of female aging. It promotes significant changes in body composition, both in fat mass as in lean body mass, leading to a decrease in muscle strength and physical performance. Objective: The aim of this study was to test whether menopausal status and hormone levels are associated with muscular strength and physical performance in middle-aged women. Methods: In a cross-sectional study it was collected sociodemographic data, gynecological history, anthropometric and biochemical measures in women aged 40 to 65 years in Parnamirim-RN. The menopause status (pre, peri and post menopause) was determined by menstrual history. All women underwent three dimensions of physical performance assessment: handgrip dynamometry, gait speed and chair stands test - Short Physical Performance Battery (SPPB). Categorical data were presented as absolute and relative frequencies. Quantitative data were showed as mean and standard deviation and the normality of distribution was verified with Kolmogorov-Smirnov (KS) test. Biochemical measures of estradiol and follicle-stimulating hormone (FSH) were transformed to log10. ANOVA with Tukey post-test for comparison of variables between the groups pre, peri and post-menopausal was performed and then multiple linear regression analyzes. Results: Two hundred and seventy eight women aged 50.2 (?5.58) years composed this study, being 50 women in premenopausal status (18%), 122 in perimenopausal (43.9%), and 106 postmenopausal stage (38.1%). The groups were different in age (p=0.001), marital relationship duration (p <0.001), number of pregnancies (p=0.001) and parity (p=0.001). Differences in biochemical measures were observed among the groups: estradiol (p<0.001), FSH (p<0.001), total cholesterol (p=0.001). There were no differences in gait velocity between menopausal status. Values in mean of grip strength decreased by postmenopausal women to perimenopausal and premenopausal ones (24.5 ? 5.1, 25.6 ? 5.4, 26.9 ? 4.9 for post-stage, pre and peri menopausas, respectively, p = 0.02) and the performance of chair stands test was better in premenopausal women compared with that in peri and postmenopausal status (p = 0.02). In multiple linear regression for muscle strength, the variables that remained were: age, estradiol and somatic symptoms measured by Menopause Rating Scale-MRS (R2=0.15). While for the xiv chair-stands test the predictors were number of births and FSH values (R2=0.04). Conclusion: There is a relationship between the stages of menopause and muscle performance in measures of grip strength and sit-up test and these are influenced by the fall of estrogens levels. Data suggest that the decrease in muscle strength and physical performance already appear in the transition to menopause stage, pointing to the need for more research in this area and appropriate preventive interventions
Introdu??o: O envelhecimento feminino tem como principal caracter?stica o hipoestrogenismo, o que promove mudan?as significativas na composi??o corporal, tanto na massa gorda, quanto na massa magra, levando ao decl?nio da for?a muscular e do desempenho funcional. Objetivo: Investigar a rela??o entre o est?gio menopausal, n?veis hormonais, desempenho muscular e funcional em mulheres de meia idade. M?todos: Realizou-se um estudo transversal, onde foram coletados dados sociodemogr?ficos, hist?rico ginecol?gico, medidas antropom?tricas e dosagens bioqu?micas de uma popula??o de mulheres entre 40 e 65 anos do munic?pio de Parnamirim-RN. A fase reprodutiva das mulheres (pr?, peri e p?s-menopausa) foi determinada pelo ciclo menstrual. Foi realizada dinamometria da preens?o palmar e aplicada a Short Physical Performance Battery (SPPB), do qual se considerou a velocidade da marcha e tempo de realiza??o do teste levantar-sentar para analisar o desempenho funcional. A apresenta??o para dados categ?ricos deu-se por frequ?ncias absolutas e relativas. Dados quantitativos foram apresentados por m?dia e desvio-padr?o e a normalidade da distribui??o foi verificada pelo teste de Kolmogorov-Smirnov (K-S). As medidas bioqu?micas do estradiol e FSH foram transformadas para log10, e em seguida, foi aplicado o teste de an?lise de vari?ncia (ANOVA), com p?s-teste de Tukey, para compara??o das vari?veis entre os grupos pr?, peri e p?s-menopausadas. Por fim, foi realizada an?lise de regress?o linear m?ltipla para identificar o grau de predi??o das vari?veis. Resultados: Foram avaliadas 278 mulheres, com m?dia de idade de 50,2 (?5,58) anos, sendo 50 em pr?-menopausa (18%), 122 em perimenopausa (43,9%) e 106 em p?s-menopausa (38,1%). Foram significativamente diferentes entre os grupos, as vari?vies idade (p=0,001), o tempo de uni?o est?vel (p<0,001), n?mero de gravidezes (p=0,001) e de partos (p=0,001). Quanto aos exames bioqu?micos, foram observadas diferen?as significativas entre os grupos para os valores de Estradiol (p<0,001), FSH (p<0,001) e Colesterol Total (p=0,001). N?o foram encontradas diferen?as na velocidade da marcha entre os diferentes est?gios. Mulheres em p?s-menopausa apresentaram os menores valores em m?dia de for?a de preens?o palmar quando comparado com em perimenopausa e estas, menores que as em pr?-menopausa (24.5 ? 5.1, 25.6 ? 5.4, 26.9 ? 4.9 para est?gios p?s, peri e pr?- xii menopausas respectivamente; p=0,02) e o desempenho do teste levantar-sentar foi melhor naquelas em pr?-menopausa quando comparado com aquela em peri e p?s-menopausa (p=0,02). No modelo de an?lise de regress?o linear m?ltipla, para a vari?vel for?a muscular, permaneceram a idade, estradiol e sintomas som?ticos do Menopause Rating Scale-MRS (R2= 0,15). A vari?vel levantar-sentar teve como preditores o n?mero de partos e o FSH (R2= 0,04). Conclus?o: Existe uma rela??o entre os est?gios de menopausa e o desempenho muscular nas medidas de for?a de preens?o palmar e teste levantar-sentar. Estas s?o influenciadas pela queda nos n?veis s?ricos de estrog?nios. Os dados sugerem que o decr?scimo da for?a muscular e as altera??es no desempenho aparecem j? na transi??o para a menopausa, em mulheres em meia-idade, apontando para a necessidade de mais estudos nesta ?rea e interven??es preventivas apropriadas
Ehle, Anita Verfasser], Vanadin R. [Akademischer Betreuer] Seifert-Klauss, and Ernst-Josef [Akademischer Betreuer] [Rummeny. "Zum Einfluss des Ovulationsgeschehens auf Knochenstoffwechsel und Knochendichte in der Perimenopause : Basis-Daten und erste Verläufe der PEKNO (Perimenopausale Knochendichte und Ovulation)-Studie / Anita Ehle. Gutachter: Vanadin R. Seifert-Klauss ; Ernst J. Rummeny. Betreuer: Vanadin R. Seifert-Klauss." München : Universitätsbibliothek der TU München, 2011. http://d-nb.info/1014330467/34.
Full textSantos, Isabelle Rodrigues dos. "Efeitos da terapia hormonal na resposta ao estresse em modelo animal de perimenopausa." Universidade de São Paulo, 2018. http://www.teses.usp.br/teses/disponiveis/17/17134/tde-18072018-170631/.
Full textPerimenopause is characterized as the period of transition from reproductive to nonreproductive life in women, and begins with the onset of clinical symptoms, lasting up to one year after the last menstrual period. This phase is characterized by irregular menstrual cycles, alterations in hormonal production, as well as by behavioral, neuroendocrine and metabolic changes, and increased vulnerability to affective disorders when compared to other phases of life. Despite the various studies on the manifestations of these symptoms during perimenopause, little is known about the changes in hypothalamic-pituitary-adrenal (HPA) axis activity and the response to stress. The chemical reagent diepoxide 4-vinylcyclohexene (VCD) accelerates the natural process of follicular atresia, enabling studies of this phase of reproductive life. Therefore, its application in rodents constitutes an excellent experimental model capable of simulating in animals what occurs during perimenopause. Thus, the objective of this study was to evaluate, in an animal model of perimenopause: 1) the endocrine responses (corticosterone and progesterone) as well as the neuronal response (parvocellular subdivisions of PVN, medial- PaMP) and posterior-PaPO and locus coeruleus - LC) to restraint stress and 2) the influence of hormonal therapy on these responses. Female Wistar rats received subcutaneous injections of Oil or VCD for 15 consecutive days, from the 28th day of life. Around the 56th to 66th day of the onset of Oil or VCD administration, the rats of the groups to be stressed received subcutaneous implants of a pellet containing placebo (PL), estradiol (E2), progesterone (P4) or estradiol + progesterone (E2P4 ). Restraint stress was applied for 30 minutes between 09:00 and 10:00 in the diestrus phase, or 20 days after the onset of hormonal therapy (VCD + E2, VCD + P4 and VCD + E2P4 groups), from 75 to 85 days after starting VCD / Oil administration. The blood was collected immediately (0min) and 60min after the end of stress, when the animals were anesthetized and perfused to take the brain for immunohistochemistry of PVN and LC. Basal corticosterone concentrations were similar between the non-stressed Oil and VCD groups. However, corticosterone secretion in response to stress was 72% lower than that of the control group. The basal progesterone concentrations of periestropausal rats were lower than those of the control rats, but the increase in the secretion of this hormone induced by stress was not different between thegroups. Centrally, in the PaMP and PaPO subdivisions of PVN as well as LC, the number of c-Fos positive neurons expressed was not different between VCD and Oil rats and the stress increased similarly the number of activated neurons in both groups. Corticosterone secretion from estradiol-treated periestropause rats, associated or not with progesterone, was further attenuated. On the other hand, in rats treated with progesterone, post-stress corticosterone concentrations were higher than those in the stressed VCD group without hormonal treatment. All groups treated with hormones increased progesterone secretion in response to stress, however this response was amplified by estradiol. None of the hormone treatments modified neuronal activity after stress in PaMP, although all hormone treatment attenuated this response in PaPo. In the LC, all treatments blocked the increase of neuronal activity induced by stress. One hour after the end of stress, corticosterone and progesterone concentrations returned to the baseline levels observed in the non-stressed rats. However, in the estradioltreated groups, progesterone levels did not return to the basal levels, these levels being significantly higher after the end of the stimulus. Taken together, our results demonstrate that in periestropause, although progesterone secretion in response to stress is preserved, the ability of the adrenal to secrete corticosterone is reduced. This reduction appears not to be associated with a central deficiency in HPA axis (PVN) or central sympathetic (LC) function, but rather to dysfunctions in adrenal steroidogenesis, which have been partially corrected by exogenous progesterone. The reduction of neuronal LC activity by ovarian steroids suggests a possible attenuation of sympathetic tone by these hormones. Furthermore, the post-stress recovery capacity of corticosterone and progesterone secretion seems to be preserved in this experimental model.
Deemer, Sarah. "Relationship of leptin, resting metabolic rate, and body composition in pre-menopausal Hispanic and non-Hispanic white women." To access this resource online via ProQuest Dissertations and Theses @ UTEP, 2008. http://0-proquest.umi.com.lib.utep.edu/login?COPT=REJTPTU0YmImSU5UPTAmVkVSPTI=&clientId=2515.
Full textSchießl, Bernadette Stefanie [Verfasser], Vanadin R. [Akademischer Betreuer] Seifert-Klauss, Vanadin R. [Gutachter] Seifert-Klauss, and Rüdiger von [Gutachter] Eisenhart-Rothe. "Beschwerden in der Perimenopause und ihr Zusammenhang mit weiblichen Hormonen der zweiten Zyklushälfte/ Lutealphase, Zyklusverlauf und Knochendichte anhand der PEKNO (Perimenopausale Knochendichte und Ovulations) - Studie / Bernadette Stefanie Schießl ; Gutachter: Vanadin R. Seifert-Klauss, Rüdiger von Eisenhart-Rothe ; Betreuer: Vanadin R. Seifert-Klauss." München : Universitätsbibliothek der TU München, 2019. http://d-nb.info/118625632X/34.
Full textKelley, Caroline Suzanne. "Sleep Quality in Midlife Women: An Examination of Mindfulness and Acceptance as Predictors." Xavier University / OhioLINK, 2017. http://rave.ohiolink.edu/etdc/view?acc_num=xavier1501076245126329.
Full textPark, Young Jin Medical Sciences Faculty of Medicine UNSW. "Effects of exercise-based lifestyle interventions on cardiovascular reactivity of untrained premenopausal women." Publisher:University of New South Wales. Medical Sciences, 2008. http://handle.unsw.edu.au/1959.4/41449.
Full textMajcher, Ryan Patrick. "Roux-en-Y Gastric Bypass Surgery During Menopause: Weight Loss Outcomes and the Resolution of Metabolic Syndrome." Bowling Green State University / OhioLINK, 2014. http://rave.ohiolink.edu/etdc/view?acc_num=bgsu1404679985.
Full textWheatley, Margaret Ann. "Personal characteristics, chronic stress, and depressive symptoms in midlife African-American women." Case Western Reserve University School of Graduate Studies / OhioLINK, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=case1239929001.
Full textMarsh, Wendy K. "Clinical Course of Bipolar Disorder During the Menopausal Transition: Comparison with Reproductive Age and Post Menopausal Women: A Master's Thesis." eScholarship@UMMS, 2010. https://escholarship.umassmed.edu/gsbs_diss/517.
Full textRojas, Cabana Angélica Sandra. "Prácticas de autocuidado que realizan las mujeres premenopáusicas del Asentamiento Humano Cerro el Sauce alto del distrito de San Juan de Lurigancho 2001." Bachelor's thesis, Universidad Nacional Mayor de San Marcos, 2003. https://hdl.handle.net/20.500.12672/2685.
Full textIn the Peru the populational structure this suffering modifications, for the biggest mature population's increment; however the social services and inside these those of health they are not prepared to acquit the necessities and requirements of this populational group, what makes them more vulnerable to the consequences of the aging process for the changes biopsicosociales that will experience and the lack of benefits of health of promotional preventive type to avoid or to diminish the risk of presenting degenerative chronic illnesses, feelings of uselessness, social and family isolation. In this context, the study of the climaterio charges importance, since this hard stage approximately 30 years, where the woman premenopáusicas requires to carry out practical healthy of autocuidado that contribute to the maintenance of her physical, structural, functional integrity, I develop and improvement of her quality of life to confront under better conditions the menopause stage and postmenopausia; in this context he/she does decide to investigate Which the autocuidado practices that the women premenopáusicas of the AAHH Hill carry out the High Sallow of the district of San Juán of Lurigancho are?. being the objectives to identify and to describe the autocuidado practices in the biological dimension and psicosocial. By means of the descriptive method, traverse in 50 women premenopáusicas of level economic partner under, it was applied by means of the interview a structured form; using the average and analysis of frequency you concluded: "That the women premenopáusicas of this populational group carry out mostly practical of non healthy autocuidado, highlighting in the biological dimension the nutritional aspect and in the dimension psicosocial the cognitive function."
Tesis
AGUILAR, C. M. "Influência do consumo da linhaça marrom e dourada nas medidas antropométricas, na composição corporal e no metabolismo ósseo de mulheres com excesso de peso na perimenopausa." Universidade Federal do Espírito Santo, 2015. http://repositorio.ufes.br/handle/10/4926.
Full textA linhaça, por ser rica em lignanas, ácidos graxos poli-insaturados, fibras solúveis e insolúveis e minerais, pode ser uma estratégia para reduzir o risco de doenças crônicas não transmissíveis como osteoporose, inflamação sistêmica, doenças cardiovasculares e para melhorar os efeitos adversos produzidos pela falta de estrogênios que inicia durante a perimenopausa. O objetivo do estudo foi determinar a influência do consumo da linhaça marrom e dourada nas medidas antropométricas, na composição corporal e metabolismo ósseo de mulheres com excesso de peso na perimenopausa. Foram selecionadas 30 mulheres com idade entre 40 e 55 anos das cidades de Alegre e Cachoeiro de Itapemirim, ES. As participantes foram divididas em três grupos experimentais: grupo controle (GC), grupo linhaça marrom (LM) e grupo linhaça dourada (LD). O GC recebeu um plano alimentar com restrição de 250 kcal diárias e orientações nutricionais. Os grupos LM e LD, além do plano alimentar e orientações nutricionais, receberam 40 g da respectiva linhaça/dia durante 12 semanas. As variáveis paramétricas foram submetidas ao teste t para comparações intragrupo e ANOVA para comparação intergrupos, complementado com o teste de comparações múltiplas de Tukey. Um valor de p<0,05 foi considerado estatisticamente significativo, utilizou-se o programa GraphPad Prism®, versão 6. Os grupos GC e LD apresentaram redução significativa no peso corporal e massa gorda (MG), e o grupo LD apresentou ainda redução do Índice de Massa Corporal (IMC). Os grupos LM e LD mostraram diminuição significativa da circunferência da cintura (CC). Houve diminuição significativa na ingestão de cálcio no GC e aumento significativo no grupo LD. Houve ainda diferença estatística intergrupo quanto à ingestão de cálcio no tempo 12 e nos valores de delta. Quanto à excreção urinária de cálcio, não foram observadas diferenças significativas (P > 0,05) inter e intragrupos. Houve aumento significativo de 25(OH)D3 no grupo GC e o 17β-estradiol não mostrou alterações significativas intragrupos, somente no delta intergrupo. A osteocalcina apresentou declínio significativo apenas para o grupo LD, assim como nos valores intergrupo no T12. O NTX-I (telopeptídeo aminoterminal de colágeno tipo I) não mostrou alterações significativas intragrupos, mas sim nos valores intergrupos no início e T12. As LM e LD contribuiram para o aumento do consumo de ácidos graxos mono e poli-insaturados, fibra alimentar e de energia. A suplementação com linhaça não mostrou incremento do estradiol, nem declínio do marcador de reabsorção óssea, provavelmetne pelo fato das participantes ainda não estarem experimentando um balanço negativo no processo de remodelação óssea. O consumo de LM e LD mostrou ter benefícios na saúde da mulher ao reduzir a CC. A ingestão de LD contribuiu ainda na redução do peso corporal, IMC e MG, sendo, portanto, mais eficaz no controle de peso das mulheres na perimenopausa.
NEVES, Fernanda Burlani. "Impacto da atividade física em mulheres na perimenopausa: fatores comportamentais e bioquímicos." Universidade Catolica de Pelotas, 2015. http://tede.ucpel.edu.br:8080/jspui/handle/tede/650.
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The purpose of this study was to contribute to the knowledege of women’s health in perimenopause phase and analyse the symptons related to this period with women’s quality of life. This period is characterized by a critical transition where several disturbances occurs due to endocrinous, psichological and biological alterations. This alterations generally are marked by periods of depression, anxiety and hormone levels alterations, particularly on strogens levels. Firstly it was conducted a bibliographic research with the objective of verify the effect of physical activity (PA) on psichological symptons of menopause period. After that, a transversal study was realized to evaluate BDNF, NGF e GDNF levels and the relation of these seric proteins levels with quality of life in climateric women. It was applied a questionnaire to identify socioeconomic, demographic and health behavior matters of these women. To evaluate quality of life it was administered Women’s Health Questionnaire (WHQ) and blood sample was colected from all sample. Statistical analyses were conducted using SPSS 21 and GraphPad Prism 6.0. Non-parametric test was performed and all values were presented as mean ± standart deviation. Spearman coeficent was used to analyse correlation between BDNF, GDNF, NGF and classifications of WHQ. p < 0,05 was cosidered significant. About serum NGF, the association between neurotrophic factor and WHQ presented a correlation between NGF and anxiety domain (r = 0,373, p ≤ 0,05) and attractiveness domain (r = 0,344, p ≤ 0,05). The literature review pointed that PA could promote reduction of stress and depressive symptons and better quality of life. Correlations between seric levels of BDNF, GDNF, NGF reveals that women who presented higher scores in anxiety and attractiveness domains had higher seric level of NGF in comparison with those who presented lower scores in these refered domains. Results suggests that this neutrophin could perform a relevant function related to behaviour during perimenopause period. Thus, more studies are needed to elucidate this question with te aim of reach clearly understanding of facts related to this period. The perspectives of this study are evaluate psichological and hormonal aspects by the effect of anaerobic ans aerobic training in cronic and acute phases, analyse cognitive function, control hormonal replacement, increase the number of participants and idealize PA as non-pharmacological treatment in perimenopause and all phases of women’s life.
Este estudo tem como objetivo contribuir para o conhecimento da saúde das mulheres na fase da perimenopausa e ainda analisar os sintomas referentes a esse período na qualidade de vida dessas mulheres. Esse período é caracterizado por uma crítica transição na qual a mulher lida com diversos transtornos consequentes de alterações endócrinas, psicológicas e biológicas que variam de acordo com as características da personalidade de cada mulher. As alterações geralmente são marcadas por períodos de depressão, ansiedade e alterações nos níveis hormonais, particularmente nos níveis de estrogênio. Inicialmente realizou-se uma pesquisa Bibliográfica com objetivo de verificar o efeito da Atividade Física (AF) nos sintomas psicológicos no período da menopausa, após desenvolveu-se um estudo transversal com objetivo de avaliar os níveis de BDNF, NGF e GDNF em mulheres climatéricas e a relação desses níveis séricos destas proteínas com a qualidade de vida de mulheres que estão passando por essa fase vital. Primeiramente foi aplicado um instrumento para identificar o nível socioeconômico e condições demográficas e questões de saúde comportamental. Para determinar a qualidade de vida foi usado Women’s Health Questionnaire (WHQ) e foi coletado amostra sanguínea de todas as participantes. Para as análises estatísticas foram realizadas utilizando SPSS 21 e GraphPad Prism 6.0. Foi realizado teste não paramétrico e todos os valores foram apresentados como média ± desvio padrão. O Coeficiente de correlação de Spearman foi utilizado para analisar a correlação entre BDNF, GDNF, NGF e as pontuações do WHQ. Os valores de p < 0,05 foram considerados estatisticamente significativos. Em relação aos níveis de NGF no soro, a associação entre fator neurotrófico e os domínios WHQ apresentou uma correlação entre os níveis de NGF com domínio ansiedade (r = 0,373, p ≤ 0,05) e domínio de atratividade (r = 0,344, p ≤ 0,05). Foi possível verificar na revisão de literatura que a AF pode promover a redução da ansiedade, do estresse e dos sintomas depressivos e a melhora da qualidade de vida. Na correlação entre os níveis séricos do BDNF, GDNF, NGF com o WHQ foi observado que as mulheres com escores mais altos em domínios de ansiedade e atratividade apresentam o maior nível sérico de NGF em comparação com aquelas com pontuações mais baixas nestes referidos domínios. Estes resultados sugerem que esta neurotrofina pode desempenhar um papel relevante na comportamento durante a perimenopausa. Deste modo, mais pesquisas são necessárias para elucidar essa questão com a intenção de alcançar claramente a compreensão dos fatos envolvidos neste período. Como perspectivas deste estudo pode-se promover a avaliação dos objetivos estudados sob o efeito de um treinamento físico aeróbio e anaeróbio na fase aguda e crônica, avaliar a função cognitiva, controlar o uso da reposição hormonal, aumentar o número das participantes e ainda realizar nas diferentes fases da vida, para de fato propor a Atividade Física como um plano de tratamento efetivo não farmacológico na perimenopausa e em outras fases da vida da mulher.
Pereira, Camila Scacco. "Efeitos do chá mate (llex paraguariensis) na estrutura óssea de ratas na perimenopausa /." Araçatuba, 2015. http://hdl.handle.net/11449/134213.
Full textCoorientadora: Adriane Belló-Klein
Banca: Fábio Erminio Mingatto
Banca: Paulo César Ciarlini
Resumo: Perimenopausa é um período marcado pela redução da densidade mineral óssea areal (aDMO) associada com um aumento do estresse oxidativo, e antioxidantes naturais têm sido utilizados como uma alternativa para reverter esta situação. Neste contexto, o presente estudo foi realizado com o objetivo de investigar os efeitos do chá mate (CM) (Ilex paraguariensis), uma bebida com alta capacidade antioxidante, no osso de ratas naturalmente perimenopausadas. Ratas Wistar perimenopausadas foram tratadas com CM na dose de 20 mg/kg de massa corpórea (m.c) durante quatro semanas e foram comparadas ao grupo não tratado. Grupo de ratas adultas foi investigado também, para confirmar os efeitos da perimenopausa. A atividade das enzimas fosfatase ácida resistente ao tartarato (TRAP) e fosfatase alcalina (FAL) foram investigados no plasma. Densidade mineral óssea areal (aDMO), área ocupada pelos adipócitos (AOA), número de osteócitos (N.Ot), volume ósseo trabecular (VTO) e imuno-histoquímica para superóxido dismutase (SOD2), osteoprotegerina (OPG), TRAP e ligante do receptor ativador do fator nuclear-kB (RANKL) foram avaliados no colo femoral. Peroxidação lipídica (MDA) e atividade da SOD foram determinadas em homogenato ósseo. O tratamento com CM foi capaz de atenuar a redução da aDMO, melhorar AOA, N.Ot e VTO. Estes resultados foram seguidos de redução de TRAP e de ALP no plasma e de MDA e SOD2 no osso. O CM minimiza o estresse oxidativo e a reabsorção óssea, atenuando assim a osteopenia de ratas na perimenopausa
Abstract: Perimenopause is a period marked by a reduction in areal bone mineral density (aBMD) associated with increased oxidative stress, and natural antioxidants have been used as an alternative to reverse this situation. In this context, the present study was to investigate the effects of mate tea (MT) (Ilex paraguariensis), a drink with high antioxidant capacity in the bone naturally perimenopausadas rats. Perimenopausadas Wistar rats were treated with MC at a dose of 20 mg / kg body mass (mc) for four weeks and compared with the untreated group. Group of adult rats was also investigated to confirm the effects of perimenopause. The activity of the enzyme tartrate resistant acid phosphatase (TRAP) and alkaline phosphatase (ALP) were investigated in plasma. Areal bone mineral density (aBMD) area occupied by adipocytes (AOA), number of osteocytes (N.Ot), trabecular bone volume (TBV) and immunohistochemistry for superoxide dismutase (SOD2), osteoprotegerin (OPG), TRAP and binder the receptor activator of the nuclear factor-kB (RANKL) were evaluated at the femoral neck. Lipid peroxidation (MDA) and SOD activity were determined in bone homogenates. Treatment with MT was able to attenuate the reduction of aBMD improve AOA N.Ot and TBV. These findings were followed by reduction of TRAP and ALP and plasma MDA and SOD2 in the bone. The MT minimizes oxidative stress and bone resorption, thereby attenuating the osteopenia of perimenopausal rats
Mestre
Pereira, Camila Scacco [UNESP]. "Efeitos do chá mate (llex paraguariensis) na estrutura óssea de ratas na perimenopausa." Universidade Estadual Paulista (UNESP), 2015. http://hdl.handle.net/11449/134213.
Full textPerimenopausa é um período marcado pela redução da densidade mineral óssea areal (aDMO) associada com um aumento do estresse oxidativo, e antioxidantes naturais têm sido utilizados como uma alternativa para reverter esta situação. Neste contexto, o presente estudo foi realizado com o objetivo de investigar os efeitos do chá mate (CM) (Ilex paraguariensis), uma bebida com alta capacidade antioxidante, no osso de ratas naturalmente perimenopausadas. Ratas Wistar perimenopausadas foram tratadas com CM na dose de 20 mg/kg de massa corpórea (m.c) durante quatro semanas e foram comparadas ao grupo não tratado. Grupo de ratas adultas foi investigado também, para confirmar os efeitos da perimenopausa. A atividade das enzimas fosfatase ácida resistente ao tartarato (TRAP) e fosfatase alcalina (FAL) foram investigados no plasma. Densidade mineral óssea areal (aDMO), área ocupada pelos adipócitos (AOA), número de osteócitos (N.Ot), volume ósseo trabecular (VTO) e imuno-histoquímica para superóxido dismutase (SOD2), osteoprotegerina (OPG), TRAP e ligante do receptor ativador do fator nuclear-kB (RANKL) foram avaliados no colo femoral. Peroxidação lipídica (MDA) e atividade da SOD foram determinadas em homogenato ósseo. O tratamento com CM foi capaz de atenuar a redução da aDMO, melhorar AOA, N.Ot e VTO. Estes resultados foram seguidos de redução de TRAP e de ALP no plasma e de MDA e SOD2 no osso. O CM minimiza o estresse oxidativo e a reabsorção óssea, atenuando assim a osteopenia de ratas na perimenopausa
Perimenopause is a period marked by a reduction in areal bone mineral density (aBMD) associated with increased oxidative stress, and natural antioxidants have been used as an alternative to reverse this situation. In this context, the present study was to investigate the effects of mate tea (MT) (Ilex paraguariensis), a drink with high antioxidant capacity in the bone naturally perimenopausadas rats. Perimenopausadas Wistar rats were treated with MC at a dose of 20 mg / kg body mass (mc) for four weeks and compared with the untreated group. Group of adult rats was also investigated to confirm the effects of perimenopause. The activity of the enzyme tartrate resistant acid phosphatase (TRAP) and alkaline phosphatase (ALP) were investigated in plasma. Areal bone mineral density (aBMD) area occupied by adipocytes (AOA), number of osteocytes (N.Ot), trabecular bone volume (TBV) and immunohistochemistry for superoxide dismutase (SOD2), osteoprotegerin (OPG), TRAP and binder the receptor activator of the nuclear factor-kB (RANKL) were evaluated at the femoral neck. Lipid peroxidation (MDA) and SOD activity were determined in bone homogenates. Treatment with MT was able to attenuate the reduction of aBMD improve AOA N.Ot and TBV. These findings were followed by reduction of TRAP and ALP and plasma MDA and SOD2 in the bone. The MT minimizes oxidative stress and bone resorption, thereby attenuating the osteopenia of perimenopausal rats
Carpio, Guzman Luis Alberto. "Valoración de la reserva ovárica por la medición del número de folículos antrales y volumen ováricos en la fase folicular precoz y su correlación con los valores de FSH." Master's thesis, Universidad Nacional Mayor de San Marcos, 2014. https://hdl.handle.net/20.500.12672/3960.
Full textTesis
Rhoads, Misty Lynn. "Hormone replacement therapy : attitudes, knowledge, and usage by perimenopausal and postmenopausal women /." View online, 2005. http://repository.eiu.edu/theses/docs/32211131275302.pdf.
Full textCornejo, Cari Vanessa Lorena. "Relación de los estilos de vida y los síntomas climatéricos en mujeres perimenopáusicas atendidas en el Hospital San Juan de Lurigancho 2014." Bachelor's thesis, Universidad Nacional Mayor de San Marcos, 2015. https://hdl.handle.net/20.500.12672/4316.
Full textOBJECTIVE: To determine the relationship between lifestyle and climacteric symptoms in perimenopausal women treated at the Hospital San Juan de Lurigancho 2014-2015. METHODOLOGY: Study of applied type, prospective cross-sectional, with descriptive correlational design in which 100 women aged 45-55 years reported any symptoms of menopause treated at the outpatient clinic of Gynecology and Obstetrics of the Hospital San Juan de Lurigancho service participated. The technique used was the interview; and as tools, two questionnaires validated. Inferential analysis for the calculation of x2 was used. RESULTS: Most respondents (81%) have an unhealthy life style and 19% healthy lifestyle. Furthermore 48% of women report mild symptoms, severe symptoms 31% and 20% mild symptoms. About styles and postmenopausal symptoms, it shows that there is a statistically significant relationship between the two (p = 0.00). CONCLUSION: If there is a relationship between lifestyle and climacteric symptoms in perimenopausal women attending the Hospital San Juan de Lurigancho. Keywords: lifestyles, menopause, perimenopause
Tesis
Christodoulou, Jacqueline Ann. "An autobiography of health : a study of health and identity amongst perimenopausal women." Thesis, Manchester Metropolitan University, 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.442700.
Full textDrakes, Imogene. "The Association of Lead with Cataracts and Vision-Related Problems in Perimenopausal Women." ScholarWorks, 2015. https://scholarworks.waldenu.edu/dissertations/139.
Full textSantiago, Vera Lúcia Gomes. "Cognição no climatério em mulheres com migrânea." Universidade Federal de Pernambuco, 2012. https://repositorio.ufpe.br/handle/123456789/12788.
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Introdução: há um consenso na prática clínica que na transição da menopausa mulheres referem queixas cognitivas, principalmente de memória. Alguns estudos mostram que sintomas psicológicos podem estar associados com prejuizos cognitivos. Essas hipóteses não têm sido comprovadas na literatura e controvérsias são apresentadas. Este estudo teve como objetivo comparar o desempenho cognitivo e suas associações com variáveis afetivas entre grupos de mulheres em fases do climatério com presença de migrânea. Método: participaram 85 mulheres distribuídas em cinco grupos (1) perimenopausa com migrânea (n=16), (2) perimenopausa sem migrânea (n=18), (3) pré-menopausa com migrânea (20), (4) pré-menopausa sem migrânea (15), (5) pós-menopausa tardia (n=16, entre 5 e dez anos após última menstruação). Em um encontro foram aplicados Inventário de Depressão, Inventário de Ansiedade, Mini-exame do Estado Mental, WAIS III (Dígitos ordem inversa e direta, Procurar Símbolos, Códigos, Raciocínio Matricial), Reprodução e Evocação Figura de Rey, Lista de Palavras de Rey, Fluência Semântica, Teste de Stroop. A análise estatística realizada foi a não paramétrica. Foram efetuadas duas comparações entre grupos: 1) pré-menopausa e perimenopausa com e sem migrânea, 2) pré-menopausa, perimenopausa e pós-menopausa. Resultados: na primeira comparação o grupo na pré-menopausa com migrânea apresentou pior desempenho nas tarefas que avaliaram o teste Stroop palavras (p= 0,04), dígitos direto (p= 0,02) e inverso (p= 0,01), raciocínio abstrato visual (p= 0,005) e ansiedade (p= 0,0006) quando comparado com o pré-menopausa sem migrânea. Os grupos na perimenopausa com e sem migrânea não apresentaram diferenças na cognição, apenas na ansiedade (p= 0,04). O grupo perimenopausa sem migrânea obteve escores piores que o pré-menopausa sem migrânea nos testes que avaliaram atenção (p= 0,04), velocidade de processamento (p= 0,02), controle inibitório (p= 0,008) e ansiedade (p= 0,04). Não foram observadas diferenças entre os grupos pré-menopausa com migrânea e o perimenopausa com migrânea. Algumas associações foram estabelecidas entre as variáveis afetivas e cognição nos quatro grupos. Na segunda comparação os sujeitos na perimenopausa e pós-menopausa obtiveram piores escores que os na pré-menopausa nas tarefas que avaliaram velocidade de processamento (p= 0,02; p= 0,04) controle inibitório (p= 0,02) e raciocínio abstrato visual (p= 0,02). Na escala de intensidade dos sintomas de ansiedade os grupos prémenopausa e pós-menopausa obtiveram menores escores que o perimenopausa (p=0,03). Algumas associações foram evidenciadas entre os escores na escala de ansiedade e depressão e os testes cognitivos no grupo pósmenopausa. Conclusão: na pré-menopausa mulheres com migrânea apresentaram diminuição da atenção, memória operacional, raciocínio abstrato visual. Mulheres na peri e pós-menopausa apresentaram diminuição da velocidade de processamento da informação, atenção, controle inibitório e raciocínio abstrato visual que as na pré-menopausa. A presença de migrânea provocou aumento da intensidade dos sintomas de ansiedade. A perimenopausa foi o período mais suscetível à ansiedade.
Tirapeli, Keny Gonçalves [UNESP]. "Alterações em marcadores do estresse oxidativo ocasionadas por diferentes tempos de tratamento com chá mate (Ilex paraguariensis) no processo de envelhecimento." Universidade Estadual Paulista (UNESP), 2014. http://hdl.handle.net/11449/123943.
Full textEritrócitos têm sido utilizados para investigar dano oxidativo e possíveis intervenções com antioxidantes no envelhecimento. O chá mate (CM) ou Ilex paraguariensis reduz o dano oxidativo, porém sua ação em fêmeas velhas ainda não foi elucidada. Neste trabalho foi investigado pela primeira vez, em ratas velhas na perimenopausa, o efeito tempo-dependente do tratamento com CM sobre o dano oxidativo e a defesa antioxidante. Os animais foram divididos em Adulta-controle (5 meses de idade), Velha-Basal (17 meses de idade), Velha tratada e não tratada. Os grupos tratados receberam CM diariamente (20 mg/kg m.c., gavagem) durante duas, quatro e seis semanas, e não tratados receberam água. A capacidade antioxidante plasmática (FRAP), malonaldeído (MDA) e as atividades da superóxido dismutase (SOD), catalase (CAT) e glutationa peroxidase (GPx) foram avaliadas nos eritrócitos. No grupo Velha-basal houve redução de FRAP e das enzimas antioxidantes, e aumento de MDA em comparação ao Adulta-controle. O CM aumentou FRAP, SOD e GPx, e reduziu MDA, após quatro e seis semanas, mas não alterou CAT. Os resultados indicam que o CM é um tratamento promissor para reduzir o acúmulo de dano oxidativo associado à idade em eritrócitos de fêmeas na perimenopausa e que o efeito na FRAP é cumulativo
Erythrocytes have been used to investigate oxidative damage and possible intervention with antioxidant in aging. Mate tea (MT) or Ilex paraguariensis reduces oxidative damage, but its action on aged females has not yet been elucidated. It was investigate, for the first time, in natural aged rats in perimenopause the time-dependent effect of MT treatment on oxidative damage and antioxidant defenses. Animals were divided into Adult-control (5 months old), Aged-baseline, Aged treated and Aged untreated. Treated groups received MT daily (20 mg/kg body weight, gavage) for two, four or six weeks, aged untreated group received water by gavage. Plasma antioxidant capacity, determined by ferric reducing antioxidant power (FRAP) assay, malondialdehyde levels (MDA) and the activities of superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx) enzymes were evaluated in erythrocytes. Aged-baseline animals (17 months) had decreased FRAP and enzymatic antioxidant defenses and increased MDA when compared to Adult-control (5 months). MT treatment increased FRAP, SOD, GPx, and decreased MDA after four weeks, but did not change CAT. MT is a promising treatment to reduce the accumulation of age-related oxidative damage in erythrocytes in aged rats in perimenopause and the effect is cumulative in FRAP
Tirapeli, Keny Gonçalves. "Alterações em marcadores do estresse oxidativo ocasionadas por diferentes tempos de tratamento com chá mate (Ilex paraguariensis) no processo de envelhecimento /." Araçatuba, 2014. http://hdl.handle.net/11449/123943.
Full textCoorientador: Adriane Belló-Klein
Banca: Fábio Erminio Mingatto
Banca: Ana Lúcia dos Anjos Ferreira
Resumo: Eritrócitos têm sido utilizados para investigar dano oxidativo e possíveis intervenções com antioxidantes no envelhecimento. O chá mate (CM) ou Ilex paraguariensis reduz o dano oxidativo, porém sua ação em fêmeas velhas ainda não foi elucidada. Neste trabalho foi investigado pela primeira vez, em ratas velhas na perimenopausa, o efeito tempo-dependente do tratamento com CM sobre o dano oxidativo e a defesa antioxidante. Os animais foram divididos em Adulta-controle (5 meses de idade), Velha-Basal (17 meses de idade), Velha tratada e não tratada. Os grupos tratados receberam CM diariamente (20 mg/kg m.c., gavagem) durante duas, quatro e seis semanas, e não tratados receberam água. A capacidade antioxidante plasmática (FRAP), malonaldeído (MDA) e as atividades da superóxido dismutase (SOD), catalase (CAT) e glutationa peroxidase (GPx) foram avaliadas nos eritrócitos. No grupo Velha-basal houve redução de FRAP e das enzimas antioxidantes, e aumento de MDA em comparação ao Adulta-controle. O CM aumentou FRAP, SOD e GPx, e reduziu MDA, após quatro e seis semanas, mas não alterou CAT. Os resultados indicam que o CM é um tratamento promissor para reduzir o acúmulo de dano oxidativo associado à idade em eritrócitos de fêmeas na perimenopausa e que o efeito na FRAP é cumulativo
Abstract: Erythrocytes have been used to investigate oxidative damage and possible intervention with antioxidant in aging. Mate tea (MT) or Ilex paraguariensis reduces oxidative damage, but its action on aged females has not yet been elucidated. It was investigate, for the first time, in natural aged rats in perimenopause the time-dependent effect of MT treatment on oxidative damage and antioxidant defenses. Animals were divided into Adult-control (5 months old), Aged-baseline, Aged treated and Aged untreated. Treated groups received MT daily (20 mg/kg body weight, gavage) for two, four or six weeks, aged untreated group received water by gavage. Plasma antioxidant capacity, determined by ferric reducing antioxidant power (FRAP) assay, malondialdehyde levels (MDA) and the activities of superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx) enzymes were evaluated in erythrocytes. Aged-baseline animals (17 months) had decreased FRAP and enzymatic antioxidant defenses and increased MDA when compared to Adult-control (5 months). MT treatment increased FRAP, SOD, GPx, and decreased MDA after four weeks, but did not change CAT. MT is a promising treatment to reduce the accumulation of age-related oxidative damage in erythrocytes in aged rats in perimenopause and the effect is cumulative in FRAP
Mestre
Sorpreso, Isabel Cristina Esposito [UNIFESP]. "Atenção integral à saúde da mulher na transição para menopausa e pós-menopausa." Universidade Federal de São Paulo (UNIFESP), 2010. http://repositorio.unifesp.br/handle/11600/10552.
Full textObjetivo: Identificar fatores que influenciam a saúde, bem como a aplicação de ações em atenção primária por equipe multidisciplinar em mulheres na transição para menopausa e pós-menopausa. Material e Métodos: O Programa Integral de Atenção à Mulher no Climatério (PIAC) foi desenvolvido no Setor de Transição para Menopausa e Pós-Menopausa da Disciplina de Endocrinologia Ginecológica do Departamento de Ginecologia, da Universidade Federal de São Paulo (UNIFESP) e resultou em dois estudos. Estudo I: Transversal com aplicação do IMK, WHQ, MSHQ e questionário de freqüência alimentar por equipe multidisciplinar com participação de 115 mulheres na transição para menopausa e pós-menopausa entre 40 e 70 anos através de convocação verbal no período de junho a agosto de 2006. Estudo II: Prospectivo com aplicação do IMK e WHQ e avaliação clínica-ginecológica com sessões de orientação por equipe multidisciplinar. Participaram deste estudo 69 pacientes divididas em grupos de pós-menopausa precoce e tardia com acompanhamento de janeiro a dezembro de 2007. Resultados: Não houve diferenças nas características clínicas, capacidade funcional, qualidade de vidas nas mulheres durante a transição para menopausa e pós-menopausa. Houve maior consumo de carboidrato entre as mulheres na pós-menopausa. Não encontramos diferenças significantes das ações em atenção primária à saúde em comparação aos grupos precoce e tardia. Entretanto, houve melhora em cada grupo nos sintomas menopausais, principalmente vasomotores na pós-menopausa tardia. Além disso, observamos melhora dos parâmetros antropométricos nos dois grupos, sem repercussões no perfil lipídico e glicêmico, bem como na qualidade de vida. Conclusão: As mulheres na transição para menopausa e pós-menopausa apresentaram condições de saúde inadequadas e sem diferenças clínicas, sociodemográficas e qualidade de vida significantes entre os diferentes estágios hormonais.
Objective: To evaluate the factors that may influence the health of women during the menopausal transition and postmenopausal women as well as the primary attention actions with multiprofissional group in early and late postmenopause. Material e Methods: The Integral Attention Programme for climateric women (PIAC) of Menopausal transition and postmenopause outpatient section of Endocrinology Gynecology division of Gynecology Department of Federal University of São Paulo (UNIFESP). We elaborated two aims: Study I: Prospective and transversal section with multiprofissional group that applied IMK, WHQ, MSHQ and nutritional questionnaires. The total of participants were: menopausal transition (n= 48) and postmenopause (n=67) through verbal calling. The study was from June to August, 2006. Study II: propective Trial with orientation section of multiprofissional time and was evaluated using the medical history and physical examination as well as IMK and WHQ questionnaires. We included 69 patients divided into two groups: early postmenopause (n=32) and late postmenopause (n=37). The length of treatment was one year from January to December, 2007. Results: There is not a difference between menopausal transition and postmenopause in the clinical queries, functional capacity and quality of life in Study I. However, there was high carbohydrate consumption in postmenopause compared to menopausal transition. In Study II, We did not find any significant differences in the influence of primary attention action when compared early postmenopause to late one. However, there was a decrease in menopausal symptoms in late postmenopause group, mainly in vasomotor symptoms. Also, the improvement in physical parameters of both groups was observed without any amelioration in lipid and glucose profile as well as in the quality of life. Conclusion: Women during the menopausal transition and postmenopause had similar and inadequate health state in the analyzed parameters.
BV UNIFESP: Teses e dissertações
Szpilfogel, Claudine C. "Factors that influence the intention to use hormone replacement therapy among pre and perimenopausal women." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk2/tape17/PQDD_0023/MQ36380.pdf.
Full textMaurer, Jaclyn. "Psychosocial and Behavioral Predictors of Energy Intake Plausibility and Weight Loss in Overweight Perimenopausal Women." Diss., Tucson, Arizona : University of Arizona, 2005. http://etd.library.arizona.edu/etd/GetFileServlet?file=file:///data1/pdf/etd/azu%5Fetd%5F1050%5F1%5Fm.pdf&type=application/pdf.
Full textMedema-Johnson, Heather Chi. "Social cognitive factors associated with moderate to vigorous physical activity in perimenopausal and postmenopausal women." Diss., University of Iowa, 2010. https://ir.uiowa.edu/etd/553.
Full textSilva, Maria Fernanda Gouveia da. ""Alterações cognitivas em mulheres com quadros depressivos na perimenopausa: o efeito da terapia de reposição hormonal com estradiol transdérmico"." Universidade de São Paulo, 2004. http://www.teses.usp.br/teses/disponiveis/5/5160/tde-13042006-164334/.
Full textPerimenopause is the female reproductive life period characterized by several changes including cognitive impairments related to hypoestrogenism. In a randomized double-blind study 16 depressive perimenopaused women took estradiol, while another group of 16 depressive perimenopaused women took placebo. Cognitive alterations associated to attention, memory and language, and estradiol hormone replacement therapy effects were evaluated. In addition, correlations among symptoms of depression and menopause, and cognitive alterations were also analyzed. The results had shown, in both groups, an improvement in inhibitory mental control, in immediate and delayed (verbal and visual) memory, and in naming capacity. In the group that received hormone replacement therapy our findings revealed a weakening of depression and menopause symptoms, which had shown no correlation with cognitive functions
López, Barrientos Erika Joana. "Intensidad del síndrome climatérico y la calidad de vida de las mujeres atendidas en el hospital San Juan de Lurigancho durante octubre a diciembre del 2014." Bachelor's thesis, Universidad Nacional Mayor de San Marcos, 2015. https://hdl.handle.net/20.500.12672/4169.
Full textTesis
Aguiar, J?lia Albuquerque. "Avaliando a cogni??o na perimenopausa e menopausa cir?rgica: a qualidade do sono, estados de humor e queixas pr?prias da menopausa predizem o desempenho cognitivo." PROGRAMA DE P?S-GRADUA??O EM PSICOBIOLOGIA, 2017. https://repositorio.ufrn.br/jspui/handle/123456789/24575.
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O aumento da expectativa de vida tem proporcionado a mulheres em todo o mundo viver cerca de metade de suas vidas adultas ap?s a menopausa, com defici?ncia de estr?genos. A priva??o hormonal evidenciada a partir desse per?odo de vida traz consigo um grande n?mero de consequ?ncias, incluindo d?ficit cognitivo, mudan?as nos estados de humor, incluindo depress?o e ansiedade, redu??o de qualidade do sono e sintomas caracter?sticos tais como ondas de calor, sudorese noturna, entre outros. O d?ficit cognitivo pode apresentar rela??o com os demais sintomas durante esse per?odo da vida. O objetivo desse estudo foi avaliar o desempenho cognitivo de mulheres perimenop?usicas em fun??o de transtornos de humor, comorbidades, sintomatologia climat?rica e ovariectomia cir?rgica. Sessenta e nove mulheres foram recrutadas na Maternidade Escola Janu?rio Cicco, Natal-RN. O desempenho cognitivo foi avaliado utilizando testes cognitivos para mem?ria verbal epis?dica, e fun??o executiva, incluindo mem?ria operacional, al?m de question?rio para queixas de mem?ria. Foram tamb?m investigados os transtornos de humor (depress?o e ansiedade) e a qualidade do sono. A presen?a de comorbidades e sintomatologia climat?rica foram obtidos atrav?s dos prontu?rios das participantes. As queixas de climat?rio foram mensuradas por meio do ?ndice de Blatt-Kupperman. Todas estas vari?veis, incluyindo a ovariectomia cir?rgica foram utilizadas como preditores do desempenho cognitivo por meio da an?lise estat?stica de modelo linear generalizado, considerando p < 0,05. Maiores sintomas de ansiedade e depress?o e qualidade de sono, foram preditores do desempenho cognitivo para fun??o executiva. Al?m disso, a sintomatologia climat?rica e os sintomas de depress?o foram preditores das queixas de mem?ria, mas as comorbidades n?o predisseram o desempenho cognitivo. A ovariectomia cir?rgica, mas n?o a perimenopausa natural, predisse o desempenho cognitivo dominu?do para mem?ria epis?dica. O hipoestrogenismo agudo vivenciado por mulheres ovariectomizadas cirurgicamente sugere uma r?pida altera??o cognitiva, provavelmente decorrente do efeito degenerativo do d?ficit hormonal. Nestes casos, a terapia de reposi??o hormonal, desde que observados os crit?rios para a sua prescri??o, possivelmente reduziria essa altera??o, como sugere a hip?tese da janela cr?tica de oportunidade. Portanto, no per?odo de transi??o perimenop?usica ocorrem altera??es fisiol?gicas pr?prias desta condi??o, al?m das repercuss?es do hipoestrogenismo sobre a cogni??o, estados de humor e qualidade do sono, de forma que abordagem integrada destes fatores pode favorecer a qualidade de vida das pacientes.
General life expectancy has increased, which has provided to women around the world live about half of their adult lives after menopause, facing estrogen deficiency. Hormone deprivation evidenced in this period of life brings with it a great number of consequences for women, including cognitive deficit, changes in mood such as depression and anxiety, reduced sleep quality, and characteristic symptoms of this period, which includes hot flashes and facial flush, among others. Hence, this research aims to assess whether mood, sleep quality, menopausal complaints and surgical ovariectomy predicted the cognitive performance in perimenopausal women. Sixry-nine women were recruited in the Climacteric Clinic at the Janu?rio Cicco Maternity-School, Natal-RN, Brazil. The assessment of cognitive performance occurred through tests of episodic memory, executive function and a questionnaire of memory complaints. Mood, sleep quality, comorbidities, menopausal complaints and surgical ovariectomy were analyzed as predictors of the cognitive performance. Comorbidities and menopausal symptoms data were collected in the participants? medical records. The menopausal complaints were measured by the Blatt-Kupperman Index. The statistical analysis was conducted using general linear model and all data analysis was considered significant when P-value was < 0.05. Higher anxiety and depression symptoms, as well as worse sleep quality, predicted executive function performance. Also, menopausal complaints and depression symptoms predicted memory complaints, but comorbidities did not predict cognitive performance. Surgical ovariectomy but not natural perimenopause predicted reduced episodic memory performance in women. The acute hypoestrogenism faced by surgically ovariectomized women indicates a fast change in cognitive performance, which may suggest the degenerative effect of hormonal absence and a preventive use of hormone therapy could possibly reduce this alteration, as supported by the critical windows hypothesis. Therefore, in the perimenopausal transition typical physiological alterations are commonly found, as well as hypoestrogenism repercussions on cognition, mood and sleep quality. Hence, an integrated approach of those factors may improve life quality for the climacteric patients.
2018-09-08
Gava, Ana Paula. "Influência do consumo das linhaças marrom e dourada sobre a composição corporal, o perfil lipídico e o estresse oxidativo em mulheres com excesso de peso em perimenopausa." Universidade Federal do Espírito Santo, 2015. http://repositorio.ufes.br/handle/10/4925.
Full textCAPES
A perimenopausa é caracterizada pela redução da produção de estrogênio, o que leva ao aumento do estresse oxidativo corporal e consequentemente à disfunção endotelial e inflamação vascular, induzindo ao aumento do risco de doenças cardiovasculares. A semente de linhaça possui quantidades consideráveis de fibras alimentares, antioxidantes, lignanas, ácido α-linolênico (ALA) e compostos fenólicos, que podem atenuar os efeitos adversos da perimenopausa. Este trabalho objetivou determinar a influência do consumo das linhaças marrom e dourada sobre os perfis antropométrico e lipídico e marcadores de estresse oxidativo em mulheres com excesso de peso na perimenopausa. As linhaças marrom e dourada foram avaliadas em termos de composição centesimal e concentração de compostos fenólicos totais e atividade antioxidante. O estudo foi aplicado em 30 voluntárias, alocadas em três grupos, grupo controle (que não recebeu linhaça), grupo linhaça marrom e o grupo linhaça dourada. Todos os grupos receberam planejamento alimentar com redução de 250 kcal/dia e orientações nutricionais. As mulheres dos grupos LM e LD foram suplementadas por 12 semanas com 40 g de farinha de linhaça ao dia. Após o período experimental foram avaliados perfil antropométrico e composição corporal, pressão, perfil lipídico, capacidade antioxidante sérica e a peroxidação lipídica, por dosagem de malondialdeído e lipoproteína de baixa densidade oxidada. Para tal, foram coletadas amostras de sangue venoso no início e ao final do período de intervenção. Foi realizado teste t (α=5%) para comparação das médias dos tempos finais e iniciais de cada grupo e ANOVA acompanhada de Tukey (α=5%), para a comparação entre os grupos. A linhaça marrom foi a que apresentou maior atividade antioxidante e não houve diferença entre as linhaças quanto à concentração de compostos fenólicos. A linhaça dourada foi a mais eficaz em diminuir peso, IMC, circunferência da cintura e massa gorda. E ainda foi o único grupo ao se diferenciar do controle quanto a fração LDL-c. Porém, não foi verificado aumento da atividade antioxidante sanguínea e nem redução da peroxidação lipídica sérica após a suplementação com as linhaças nos grupos experimentais. Pode-se concluir que, a linhaça dourada foi a mais eficaz para a diminuição de parâmetros antropométricos e fração LDL-c.
Perimenopause is characterized by reduced estrogen production, which leads to increased oxidative stress body and consequently to vascular endothelial dysfunction and inflammation, leading to increased risk of cardiovascular disease. Flaxseed has considerable amounts of dietary fiber, lignans antioxidants, α-linolenic acid (ALA) and phenolic compounds, which can mitigate the adverse effects of perimenopause. This study aimed to determine the influence of consumption of brown and golden linseeds on anthropometric and lipid profiles and oxidative stress markers in overweight women in perimenopause. The brown and golden flaxseed were evaluated in terms of chemical composition and concentration of phenolic compounds and antioxidant activity. The study was applied on 30 volunteers, divided into three groups, the control group (which received no linseed), brown flaxseed group and golden flaxseed group. All groups received a food planning with a reduction of 250 kcal / day and nutritional guidelines. Women of LM and LD groups were supplemented by 12 weeks with 40 g of flaxseed flour per day. After the trial period parameters evaluated were anthropometric profile and body composition, blood pressure, lipid profile, serum antioxidant capacity and lipid peroxidation, for dosage of malondialdehyde and oxidized low-density lipoprotein. To do this, venous blood samples were collected at the beginning and in the end of the intervention period. It was held t test (α = 5%) compared to the averages of final and initial time of each group and ANOVA followed by Tukey (α = 5%), for comparison between groups. The brown flaxseed showed the highest antioxidant activity and no difference between the linseeds on the concentration of phenolic compounds. The golden flaxseed was the most effective in reducing weight, BMI, waist circumference and fat mass. And it was the only group different to the control group for LDL-c fraction. However, it was not verified an increase in blood antioxidant activity nor a reduction in serum lipid peroxidation after supplementation with flaxseed in the experimental groups. It can be concluded that the golden flaxseed was the most effective for the decrease of anthropometric parameters and LDL-c.
Lindoff, Claes. "Haemostasis during pregnancy and perimenopausal age studies of fibrinolytic components and coagulation factors involved in vascular disease /." Lund : Dept. of Obstetrics and Gynaecology, Lund University, 1994. http://catalog.hathitrust.org/api/volumes/oclc/39750405.html.
Full textDook, Jan. "The effect of long term training on the bone mineral density and muscle strength of perimenopausal athletes." Thesis, Edith Cowan University, Research Online, Perth, Western Australia, 1994. https://ro.ecu.edu.au/theses/1093.
Full textAmorim, Ariane Dias de. "Efeitos da linhaça marrom e dourada na glicemia, na permeabilidade intestinal e na endotoxemia de mulheres com excesso de peso na perimenopausa." Universidade Federal do Espírito Santo, 2015. http://repositorio.ufes.br/handle/10/4932.
Full textCAPES
A menopausa é uma fase da vida da mulher marcada por um aumento de deposição de gordura corporal e com isso desenvolvimento de doenças crônicas não trasmíssiveis. Neste aspecto, a microbiota intestinal tem desempenhado um evidente papel na regulação da homeostase. Abordagens terapêuticas com alimentos ricos em antioxidante e fibras são importantes na redução da inflamação. Assim, este estudo avaliou o efeito da linhaça marrom e dourada sobre as medidas antropométricas, a permeabilidade intestinal, a endotoxemia e a glicemia de jejum de mulheres com excesso de peso na perimenopausa. Durante um período de 12 semanas, 30 mulheres de 40 a 55 anos, com IMC > 25 kg /m2 e < 35 kg /m2, glicemia inferior a 126 mg/dl, foram selecionadas e alocadas em um grupo controle (CT), grupo linhaça marrom (LM) e grupo linhaça dourada (LD). Os grupos LM e LD receberam 40g de linhaça triturada para consumo diário. Todas voluntárias do estudo receberam planejamento dietético com restrição de 250 kcal, orientações nutricionais e passaram por consultas periódicas. No início e no final deste período, foram coletadas amostras de sangue venoso para determinar glicemia de jejum e níveis de lipopolissacarídeo (LPS) sérico. A análise da permeabilidade intestinal foi realizadapor meio da coleta de urina para avaliação da excreção de manitol, excreção de lactulose e razão de lactulose/manitol. Os dados obtidos foram analisados com auxílio do software GraphPad Prism®, versão 6., com um nível de significância de 5%. Os dados de distribuição paramétrica foram submetidos ao teste t e ANOVA, seguido de teste de Tukey e foi empregada correlação Pearson. Para os dados de distribuição não paramétrica utilizou-se o teste de Wilcoxon e teste de Kruskal-Wallis, acompanhado de pelo teste de Dunns e correlação de Spearman. As linhaças marrom e dourada foram semelhantes em relação a sua composição. Além disso, não houve diferenças significaticas entre os grupos (CT, LM e LD) (p>0,05) quanto à antropometria (peso, IMC, circuferência da cintura (CC)), composição corporal (massa magra (MM), massa gorda (MG) e % de gordura corporal (%GC)) e valores de glicemia de jejum. Observou-se reduções significativas do peso corporal, IMC e MG do grupo CT e grupo LD, quando camparado ao tempo basal. Quanto à CC, houve reduções significativas (p<0,05) nos grupos LM e LD. A restrição média alimentar dos grupos foram de (337, 156 e 100 kcal/dia) grupos CT, LM e LD, respectivamente.De forma geral, não houve correlação significativa (p<0,05) para a variáveis permebilidade intestinal vs glicemia de jejum vs LPS. No decorrer do estudo ocorreu redução significativa (p<0,05) na permeabilidade intestinal nos grupos (CT, LM e LD) e também nos níveis de LPS no grupo LM e no grupo LD. Pode-se concluir que as linhaças marrons e douradas foram eficazes redução da permeabilidade intestinal e endotoxemia. A linhaça dourada apresentou melhores efeitos sobre medidas antropométricas e de composição corporal, quando comparada à variedade marrom.
Ferreira, Maycon Junior. "Influência do gênero e treinamento físico aeróbio sobre a modulação autonômica cardíaca, pressão arterial e biomarcadores de estado redox em mulheres na perimenopausa e homens /." Rio Claro, 2016. http://hdl.handle.net/11449/138338.
Full textCoorientador: Carlos Henrique Grossi Sponton
Banca: Maria Andréia Delbin
Banca: Kátia de Angelis
Resumo: O objetivo do presente estudo foi avaliar a influência do gênero e do treinamento físico aeróbio sobre a modulação autonômica cardiovascular, produção de óxido nítrico (NO), biomarcadores de estado redox e pressão arterial em mulheres na perimenopausa (MP) e homens (H) de mesma idade. Quinze MP (47,8±0,9 anos) e dezesseis H (50,7±1,2 anos) completaram todas as etapas do estudo. O desenho experimental foi composto por 12 - 14 semanas. Como parâmetros antropométricos, foram avaliadas massa corporal (MC), índice de massa corporal (IMC) e circunferência abdominal (CA). A frequência cardíaca (FC) de repouso foi avaliada na posição sentada e sua variabilidade (VFC) foi determinada posteriormente. A pressão arterial sistólica (PAS) e diastólica (PAD) foram medidas durante repouso e através da monitorização ambulatorial (MAPA). A variabilidade da PA (VPA) foi calculada usando o índice de variabilidade média real. O consumo pico de oxigênio (VO2 pico) foi determinado indiretamente através do teste de 1 milha. Amostras de sangue venoso foram coletadas após jejum noturno de 12 horas para análise de perfil lipídico e frações, creatinina e glicemia. Níveis de nitrito/nitrato (NOx-) e malondialdeído (MDA), atividade da superóxido dismutase (SOD) e catalase (CAT) foram realizadas através do método colorimétrico em espectrofotômetro. O TFA consistiu de três vezes/semana de caminhada em esteira durante 30 - 40min, na intensidade da máxima fase estável de lactato por 8 semanas. Como resultados, comparado aos H, as MP apresentaram uma menor MC e CA antes (-14,66% e -11,93%, respectivamente) e após o TFA (-13,74% e -11,32%). Já o TFA reduziu a MC (-1,38%), IMC (-1,30%) e CA (-2,56%) apenas nos H. Da mesma forma, foi observado um menor VO2 pico em ambos os momentos (-22,42% e -20,24%) e maior FC de repouso antes do TFA (13,69%) nas MP comparado (Resumo completo clicar acesso eletrônico abaixo)
Abstract: The aim of this study was to evaluate the influence of gender and aerobic exercise training on cardiovascular autonomic modulation, nitric oxide (NO) production, biomarkers of redox state and blood pressure in perimenopause women (PW) and men (M) of the same aged. Fifteen PW (47.8 ± 0.9 yrs) and sixteen M (50.7 ± 1.2 yrs) completed all the stages of study. The experimental design was consisted by 12-14 weeks. As anthropometric parameters were assessed body mass (BM), body mass index (BMI) and abdominal circumference (AC). Resting heart rate (HR) was measured in a sitting position and its variability (HRV) was determined later. Systolic (SBP) and diastolic blood pressure (DBP) were measured at rest and by ambulatory blood pressure (BP) monitoring (ABPM). BP variability (BPV) was calculated using the average real variability index. The peak oxygen consumption (peak VO2) was determined indirectly through the one mile test. Venous blood sample were collected after overnight fast of 12 hours for lipid profile analysis and fractions, creatinine and glycemia. Nitrite/nitrate (NOx-) and malondialdehyde (MDA) levels, superoxide dismutase (SOD) and catalase activity were performed through of colorimetric method in spectrophotometer. The AET consisted of 3 times/week of walking on treadmill, 30 - 40 minutes, at maximal lactate steady state intensity for 8 weeks. As results, compared with M, PW presented a lower BM and AC before (-14.66% and -11.93%, respectively) and after AET (-13.74% e -11.32%). However, AET reduced BM (-1.38%), BMI (-1.30%) and AC (-2.56%) only in M. Similarly, was observed a lower peak VO2 in both moments (-22.42% and -20.24%) and higher resting HR before AET (13.69%) in PW compared to M, and AET promote an increase peak VO2 in both groups (M: 2.08% and PW: 4.95%). In analysis of ABPM, were observed a lower daytime SBP (-7.02%) and 24h (-7.36%) in PW before AET. Since both moments, (Complete abstract click electronic access below)
Mestre
McArthur, Deanne M. "Evaluation of Factors Influencing Engagement in Physical Activity in Women during the Transition to Menopause." Thesis, Université d'Ottawa / University of Ottawa, 2012. http://hdl.handle.net/10393/20632.
Full textLima, José Emilio Mendes. "Tradução, adaptação cultural e validação da versão em português brasileiro da Escala Cervantes de qualidade de vida relacionada com a saúde da mulher durante a perimenopausa e na pós-menopausa." reponame:Biblioteca Digital de Teses e Dissertações da UFRGS, 2009. http://hdl.handle.net/10183/17764.
Full textTorres, Leguía Alexandra. "Conocimientos y prácticas sobre el autocuidado en la premenopausia en las usuarias de un centro de salud de Lima, 2017." Bachelor's thesis, Universidad Nacional Mayor de San Marcos, 2018. https://hdl.handle.net/20.500.12672/7685.
Full textTesis
Wimmer, Teresa Maria [Verfasser], Vanadin R. [Akademischer Betreuer] Seifert-Klauss, Markus [Akademischer Betreuer] Schwaiger, and Marion Brigitta [Akademischer Betreuer] Kiechle. "Zum Einfluss des Ovulationsgeschehens auf die Veränderung der Knochendichte: 2-Jahres-Daten der PEKNO (Perimenopausale Knochendichte und Ovulation)- Studie / Teresa Maria Wimmer. Gutachter: Markus Schwaiger ; Vanadin R. Seifert-Klauss ; Marion Brigitta Kiechle. Betreuer: Vanadin R. Seifert-Klauss." München : Universitätsbibliothek der TU München, 2013. http://d-nb.info/1047185407/34.
Full textLu, Shin-Yi, and 盧欣怡. "The relationship among life event stress, perimenopause attitude, climacteric symptoms, self-concept, and depression in women during perimenopause." Thesis, 2003. http://ndltd.ncl.edu.tw/handle/42340168823173325149.
Full text國立成功大學
護理學系碩博士班
91
The purpose of this study was to explore the relationship among demographic data, life-event stress, perimenopause attitude, climacteric symptoms, self-concepts and depression of women during perimenopause. A cross-sectional design used self-administered questionnaires or interview was applied in this study. The subjects aged between 45 and 55 were selected by cluster random sampling of Tainan city in southern Taiwan. There were 43 district areas and Da Shan, Shjian and Wen Yuan district areas were selected. Total of 266 valid subjects were in this study. Data were collected from February to April 2003. The following 5 instruments were used: the Adult Life-Event Scale, the Perimenopause Attitude Scale, the Greene Climacteric Symptom Scale, the Tennessee Self-Concept Scale Chinese Version and the Center of Epidemiological Study Depression Scale. Multiple regression analysis was used to analyze the data. The results show that: (1) women who have depression symptoms are about 31.2%, that is about one-third women have depression; (2) women who are currently unemployed, with physical disease, have used hormone replacement therapy (HRT) frequently have more depression symptoms; there are no significant difference of depression symptoms between different marriage status, educational level, menopause stages of perimenopause women, (3) 91.8% women view that perimenopause as a natural phenomenon, women whose education level below elementary or who have used hormone replacement therapy have more negative attitude toward perimenopause; (4) about 92.5% women whose self-concept are at norm range as general adult, compare to the norm more women get lower score on self-concept subscale: Physical Self-concept, Moral Self-concept, Psychological Self- concept, Family Self-concept, Social Self-concept and Work Self-concept, women who are currently unemployed, who have used HRT have more negative attitude toward perimenopause; (5) the correlation between life event stress and depression, climacteric symptoms and depression are positive; the correlation between perimenopause attitude and depression, self-concept and depression are negative; and (6) negative self-concept, more climacteric symptoms, more life event stress and higher educational level are the most important variables to predict depression of women during perimenopause. The self-concept subscales: Family Self-concept, Physical Self-concept and Social Self-concept also predict depression. The results of this study will help us to know more about the depression during perimenopause and we may apply these findings to develop interventions for preventing depression and promoting women’s mental health.
Chau, Mei-Ling, and 趙美玲. "The Sexual Impact among Perimenopause Women in Taiwan." Thesis, 2004. http://ndltd.ncl.edu.tw/handle/20488360940622775489.
Full text長庚大學
護理學研究所
92
The purpose of the study was to explore sexual impact among perimenopause women in Taiwan. The research design of this study was based on phenomenological methods qualitatively . Snowing ball and purposeful sampling methods were used. Partial samples were from perimenopause women’s developmental group. The number of participants in this study was twenty-one women. Either one or two individual tape record interviews was used in the study. Process recording was established based upon those interviews. Data was analyzed by using Colaizzi’s control analysis. The major themes emerged as:Sexual role strain, Aging image, Marriage relationship reconstruction and Aware of life progress himself. Sexual role strain includes: Physical disturbance, approach-Avoidance conflict and sexual role to end. Aging image is: Physical degradation and Body imagine change. Marriage relationship reconstruction has aloof relationship, develop equal and partnership, and realize generalize sexual behavior. Aware of life progress himself are:Extricate and loss, maintain harmony house, displacement and surmount. This research shows that perimenopause women’s sexual life changed not only in their quality but also in their quantity. Perimenopause women perceived factors of physical, spouse, marriage relationship and psychosocial concern. Hence, it is important for professional must holism consideration, couraged spouses involved are aware of the sexual belief among their culture. Provide a health consultant to reach health promotion.
Su, Mei-Chen, and 蘇美禎. "An Exploratory of the Health Needs and Its Related Factors of Women among Perimenopause." Thesis, 2000. http://ndltd.ncl.edu.tw/handle/23051199551288558225.
Full text國立臺灣大學
護理學研究所
88
The main purpose of this study was to explore the health needs of women among perimenopause and the related factors. This study was conducted in a cross-sectional design. Data were collected by interview including the demographic data, health status, symptoms distress and health needs, from Feb. to Apr. 2000. Study subjects were recruited from two groups perimenopausal women, one was selected by purposive sampling in a medical center in Taipei, the other was selected by systematic random sampling in two urban districts in Taipei. Complete data were obtained on 75 subjects for two groups respectively. The data was analyzed by t-test, one-way ANOVA, Pearson’s product-moment correlation, Scheff’s test and stepwise regression. The results of study were as follows: 1. Most of subjects in this study were married, elementary- below educational level,live with children, without occupation, 61.3% taking hormone replace treatment, 39.3% without chronic disease and were satisfied with their family lives and social lives. 2. The health needs of women among perimenopause were: (1) The level of importance of entire health needs was median. The order of importance of health needs was ranked as : informational, psychosocial support and physical health needs. (2) The level of satisfaction of entire health needs was low. The order of satisfaction of health needs was ranked as : psychosocial support, informational and physical health needs. 3. Subjects having higher level of education, younger, better economic status had higher level of importance of the entire health needs. 4. Subjects having higher level of education, better economic status, willing to discuss perimenopausal experience with others, higher level of satisfaction with their family lives and social lives had higher satisfaction level of entire health needs. 5. Self-rated health was found negatively correlated with the importance of entire health needs, and positively correlated with the satisfaction of psychosocial support health needs. 6. The more limited of activity of daily living, the higher importance level of entire health needs, physical and informational health needs; but the lower satisfaction level of physical, psychosocial support and informational health needs. 7. The better of mental health status, the lower importance and higher satisfaction level of entire and subscale health needs. 8. The frequency of symptom appearance and the level of symptom disturbance were found positively correlated with the importance of health needs, and negatively correlated with the satisfaction of health needs. 9. Mental health status, education and limited level of activity of daily living explained 22.7% of the variance of the importance of entire health needs. 10.Education, social lives satisfaction and experience discussing perimenopause explained 35.3% of the variance of the satisfaction of entire health needs. Based on study results the following suggestions were made: (1)The study results of the order of the most importance and the least satisfaction,could be used for nursing intervention. (2)Nurses, nomatter in hospital or community, could provide health promotion and counseling service about perimenopause, in order to solve many midlife women’s doubtfulness.