Academic literature on the topic 'Periconception period'

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Journal articles on the topic "Periconception period"

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Fazeli, Alireza, and William V. Holt. "Cross talk during the periconception period." Theriogenology 86, no. 1 (July 2016): 438–42. http://dx.doi.org/10.1016/j.theriogenology.2016.04.059.

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Schelbach, Cheryl J., Rebecca L. Robker, Brenton D. Bennett, Ashley D. Gauld, Jeremy G. Thompson, and Karen L. Kind. "Altered pregnancy outcomes in mice following treatment with the hyperglycaemia mimetic, glucosamine, during the periconception period." Reproduction, Fertility and Development 25, no. 2 (2013): 405. http://dx.doi.org/10.1071/rd11313.

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Exposure of cumulus–oocyte complexes to the hyperglycaemia mimetic, glucosamine, during in vitro maturation impairs embryo development, potentially through upregulation of the hexosamine biosynthesis pathway. This study examined the effects of in vivo periconception glucosamine exposure on reproductive outcomes in young healthy mice, and further assessed the effects in overweight mice fed a high-fat diet. Eight-week-old mice received daily glucosamine injections (20 or 400 mg kg–1) for 3–6 days before and 1 day after mating (periconception). Outcomes were assessed at Day 18 of gestation. Glucosamine treatment reduced litter size independent of dose. A high-fat diet (21% fat) for 11 weeks before and during pregnancy reduced fetal size. No additional effects of periconception glucosamine (20 mg kg–1) on pregnancy outcomes were observed in fat-fed mice. In 16-week-old mice fed the control diet, glucosamine treatment reduced fetal weight and increased congenital abnormalities, but did not alter litter size. As differing effects of glucosamine were observed in 8-week-old and 16-week-old mice, maternal age effects were assessed. Periconception glucosamine at 8 weeks reduced litter size, whereas glucosamine at 16 weeks reduced fetal size. Thus, in vivo periconception glucosamine exposure perturbs reproductive outcomes in mice, with the nature of the outcomes dependent upon maternal age.
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Rajila Rajendran, Hannah Sugirthabai, Thotakura Balaji, Jyothi Ashok Kumar, Santhosh Kumar, and Vaithianathan Gnanasundaram. "Folic Acid Supplementation on Fetal Growth at Different Gestational Ages." Biomedical and Pharmacology Journal 14, no. 4 (December 30, 2021): 1761–66. http://dx.doi.org/10.13005/bpj/2275.

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Introduction: Folate, Vitamin B9, is found naturally in our day to day foods. It is vital for synthesis of DNA and normal cell division in humans. Studies have revealed constantly that maternal folic acid[FA] intake prior to and in early conception decreases neural tube defects. Aim: The aim of the current study is to evaluate the relationship between FA intake by the mother during conception and fetal growth at different gestational ages and also if, periconceptional and preconceptional FA intake has a positive effect on fetal growth, hence reducing the risk of low birth weight babies or small for gestational age (SGA) babies. Materials and methods: 180 pregnant women were classified based on their period of FA intake as preconception, periconception FA intake and nil FA intake. Standard fetal biometric parameters were measured using ultrasonogram during the 1st , 2nd and 3rd trimester of their pregnancy. Results: Preconception FA intake had a positive effect on fetal growth as compared to those who abstained from FA supplementation. Intake during preconception and peri-conception i.e. immediately after confirmation of pregnancy was found to have a reduced risk of low fetal weight as against those who did not consume FA. Fetal biometry showed significant difference between preconception and periconception groups. Conclusion: In conclusion, preconceptional and periconceptional FA supplementation of 0.4-0.5 mg/day was positively affecting fetal growth and caused an optimal birth weight by decreasing the incidence of low birth weight.
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Matusiak, Kristine, Helen L. Barrett, Leonie K. Callaway, and Marloes Dekker Nitert. "Periconception Weight Loss: Common Sense for Mothers, but What about for Babies?" Journal of Obesity 2014 (2014): 1–10. http://dx.doi.org/10.1155/2014/204295.

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Obesity in the childbearing population is increasingly common. Obesity is associated with increased risk for a number of maternal and neonatal pregnancy complications. Some of these complications, such as gestational diabetes, are risk factors for long-term disease in both mother and baby. While clinical practice guidelines advocate for healthy weight prior to pregnancy, there is not a clear directive for achieving healthy weight before conception. There are known benefits to even moderate weight loss prior to pregnancy, but there are potential adverse effects of restricted nutrition during the periconceptional period. Epidemiological and animal studies point to differences in offspring conceived during a time of maternal nutritional restriction. These include changes in hypothalamic-pituitary-adrenal axis function, body composition, glucose metabolism, and cardiovascular function. The periconceptional period is therefore believed to play an important role in programming offspring physiological function and is sensitive to nutritional insult. This review summarizes the evidence to date for offspring programming as a result of maternal periconception weight loss. Further research is needed in humans to clearly identify benefits and potential risks of losing weight in the months before conceiving. This may then inform us of clinical practice guidelines for optimal approaches to achieving a healthy weight before pregnancy.
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Timmermans, Sarah, Vincent W. V. Jaddoe, Albert Hofman, Régine P. M. Steegers-Theunissen, and Eric A. P. Steegers. "Periconception folic acid supplementation, fetal growth and the risks of low birth weight and preterm birth: the Generation R Study." British Journal of Nutrition 102, no. 5 (September 14, 2009): 777–85. http://dx.doi.org/10.1017/s0007114509288994.

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Countries worldwide, including the Netherlands, recommend that women planning pregnancy use a folic acid supplement during the periconception period. Some countries even fortify staple foods with folic acid. These recommendations mainly focus on the prevention of neural tube defects, despite increasing evidence that folic acid may also influence birth weight. We examined whether periconception folic acid supplementation affects fetal growth and the risks of low birth weight, small for gestational age (SGA) and preterm birth, in the Generation R Study in Rotterdam, the Netherlands. Main outcome measures were fetal growth measured in mid- and late pregnancy by ultrasound, birth weight, SGA and preterm birth in relation to periconception folic supplementation (0·4–0·5 mg). Data on 6353 pregnancies were available. Periconception folic acid supplementation was positively associated with fetal growth. Preconception folic acid supplementation was associated with 68 g higher birth weight (95 % CI 37·2, 99·0) and 13 g higher placental weight (95 % CI 1·1, 25·5), compared to no folic acid supplementation. In these analyses parity significantly modified the effect estimates. Start of folic acid supplementation after pregnancy confirmation was associated with a reduced risk of low birth weight (OR 0·61, 95 % CI 0·40, 0·94). Similarly, reduced risks for low birth weight and SGA were observed for women who started supplementation preconceptionally, compared to those who did not use folic acid (OR 0·43, 95 % CI 0·28, 0·69 and OR 0·40, 95 % CI 0·22, 0·72). In conclusion, periconception folic acid supplementation is associated with increased fetal growth resulting in higher placental and birth weight, and decreased risks of low birth weight and SGA.
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González-Brusi, Leopoldo, Blanca Algarra, Carla Moros-Nicolás, Mª José Izquierdo-Rico, Manuel Avilés, and Maria Jiménez-Movilla. "A Comparative View on the Oviductal Environment during the Periconception Period." Biomolecules 10, no. 12 (December 17, 2020): 1690. http://dx.doi.org/10.3390/biom10121690.

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The oviduct plays important roles in reproductive events: sperm reservoir formation, final gamete maturation, fertilization and early embryo development. It is well known that the oviductal environment affects gametes and embryos and, ultimately, the health of offspring, so that in vivo embryos are better in terms of morphology, cryotolerance, pregnancy rates or epigenetic profile than those obtained in vitro. The deciphering of embryo–maternal interaction in the oviduct may provide a better understanding of the embryo needs during the periconception period to improve reproductive efficiency. Here, we perform a comparative analysis among species of oviductal gene expression related to embryonic development during its journey through the oviduct, as described to date. Cross-talk communication between the oviduct environment and embryo will be studied by analyses of the secreted or exosomal proteins of the oviduct and the presence of receptors in the membrane of the embryo blastomeres. Finally, we review the data that are available to date on the expression and characterization of the most abundant protein in the oviduct, oviductin (OVGP1), highlighting its fundamental role in fertilization and embryonic development.
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van der Windt, Melissa, Rianne Maria van der Kleij, Katinka Marianne Snoek, Sten Paul Willemsen, Ramon Henny Maria Dykgraaf, Joop Stephanus Elisabeth Laven, Sam Schoenmakers, and Régine Patricia Maria Steegers-Theunissen. "Impact of a Blended Periconception Lifestyle Care Approach on Lifestyle Behaviors: Before-and-After Study." Journal of Medical Internet Research 22, no. 9 (September 30, 2020): e19378. http://dx.doi.org/10.2196/19378.

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Background Periconception lifestyle behaviors affect maternal, paternal, offspring, and transgenerational health outcomes. Previous research in other target populations has shown that personalized lifestyle interventions, in which face-to-face counseling and eHealth (“blended care”) are combined, may effectively target these lifestyle behaviors. Objective We aimed to assess the effectiveness of a periconceptional lifestyle intervention on the improvement of specific lifestyle components. Methods A blended periconception lifestyle care approach was developed, combining the outpatient lifestyle counseling service “Healthy Pregnancy” with the eHealth platform “Smarter Pregnancy” (www.smarterpregnancy.co.uk) in which lifestyle was coached for 24 weeks. All couples contemplating pregnancy or already pregnant (≤12 weeks of gestation) who visited the outpatient clinics of the Department of Obstetrics and Gynecology at the Erasmus University Medical Center (Erasmus MC), Rotterdam, the Netherlands, between June and December 2018, were invited to participate. We measured changes in lifestyle behaviors at weeks 12 and 24 compared with baseline. Generalized estimating equations were used to analyze the changes in lifestyle behaviors over time. Subgroup analyses were performed for women with obesity (BMI ≥30 kg/m2), women pregnant at the start of the intervention, and those participating as a couple. Results A total of 539 women were screened for eligibility, and 450 women and 61 men received the blended periconception intervention. Among the participating women, 58.4% (263/450) were included in the preconception period. Moreover, 78.9% (403/511) of the included participants completed the online lifestyle coaching. At baseline, at least one poor lifestyle behavior was present in most women (379/450, 84.2%) and men (58/61, 95.1%). In the total group, median fruit intake increased from 1.8 to 2.2 pieces/day (P<.001) and median vegetable intake increased from 151 to 165 grams/day (P<.001) after 24 weeks of online coaching. The probability of taking folic acid supplementation among women increased from 0.97 to 1 (P<.001), and the probability of consuming alcohol and using tobacco in the total group decreased from 0.25 to 0.19 (P=.002) and from 0.20 to 0.15 (P=.63), respectively. Overall, the program showed the strongest effectiveness for participating couples. Particularly for vegetable and fruit intake, their consumption increased from 158 grams/day and 1.8 pieces/day at baseline to 190 grams/day and 2.7 pieces/day at the end of the intervention, respectively. Conclusions We succeeded in including most participating women in the preconception period. A high compliance rate was achieved and users demonstrated improvements in several lifestyle components. The blended periconception lifestyle care approach seems to be an effective method to improve lifestyle behaviors. The next step is to further disseminate this approach and to perform a randomized trial to compare the use of blended care with the provision of only eHealth. Additionally, the clinical relevance of these results will need to be substantiated further.
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Mamon, Mark Anthony C., Cheska May M. Menodiado, Glenn L. Siasu, and Gliceria B. Ramos. "Selenium supplementation within the periconception period: Influence on maternal liver and renal histoarchitecture." Asian Pacific Journal of Reproduction 5, no. 4 (July 2016): 295–300. http://dx.doi.org/10.1016/j.apjr.2016.06.014.

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Lassi, Zohra S., Sophie G. E. Kedzior, Wajeeha Tariq, Yamna Jadoon, Jai K. Das, and Zulfiqar A. Bhutta. "Effects of Preconception Care and Periconception Interventions on Maternal Nutritional Status and Birth Outcomes in Low- and Middle-Income Countries: A Systematic Review." Nutrients 12, no. 3 (February 26, 2020): 606. http://dx.doi.org/10.3390/nu12030606.

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Pregnancy in adolescence and malnutrition are common challenges in low- and middle-income countries (LMICs), and are associated with many complications and comorbidities. The preconception period is an ideal period for intervention as a preventative tactic for teenage pregnancy, and to increase micronutrient supplementation prior to conception. Over twenty databases and websites were searched and 45 randomized controlled trials (RCTs) or quasi-experimental interventions with intent to delay the age at first pregnancy (n = 26), to optimize inter-pregnancy intervals (n = 4), and supplementation of folic acid (n = 5) or a combination of iron and folic acid (n = 10) during the periconception period were included. The review found that educational interventions to delay the age at first pregnancy and optimizing inter-pregnancy intervals significantly improved the uptake of contraception use (RR = 1.71, 95% CI = 1.42–2.05; two studies, n = 911; I2 = 0%) and (RR = 2.25, 95% CI = 1.29–3.93; one study, n = 338), respectively. For periconceptional folic acid supplementation, the incidence of neural tube defects were reduced (RR = 0.53; 95% CI = 0.41–0.77; two studies, n = 248,056; I2 = 0%), and iron-folic acid supplementation improved the rates of anemia (RR = 0.66, 95% CI = 0.53–0.81; six studies; n = 3430, I2 = 88%), particularly when supplemented weekly and in a school setting. Notwithstanding the findings, more robust RCTs are required from LMICs to further support the evidence.
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van Zundert, Sofie, Simone van der Padt, Sten Willemsen, Melek Rousian, Mina Mirzaian, Ron van Schaik, Régine Steegers-Theunissen, and Lenie van Rossem. "Periconceptional Maternal Protein Intake from Animal and Plant Sources and the Impact on Early and Late Prenatal Growth and Birthweight: The Rotterdam Periconceptional Cohort." Nutrients 14, no. 24 (December 14, 2022): 5309. http://dx.doi.org/10.3390/nu14245309.

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Plant-based diets continue to rise in popularity, including among women of reproductive age, while consequences for pregnancy outcomes have hardly been studied. During pregnancy, maternal diet is the only source of proteins for the developing fetus. Hence, we investigated the effects of periconceptional maternal animal and plant protein intake on prenatal growth and birthweight. 501 pregnancies were included from the prospective Rotterdam Periconceptional Cohort. Embryonic growth was depicted by crown-rump length (CRL) and embryonic volume (EV) at 7, 9 and 11 weeks using 3D ultrasound scans. Estimated fetal weight (EFW) at 20 weeks and birthweight were retrieved from medical records and standardized. Multivariable mixed models were used for CRL and EV trajectories, and linear regression for EFW and birthweight. A 10 g/day higher maternal animal protein intake was positively associated with increased embryonic growth (CRL: β = 0.023 √mm, p = 0.052; EV: β = 0.015 ∛cm, p = 0.012). A positive association, albeit non-significant, was found between maternal animal protein intake and EFW, and birthweight. No clear associations emerged between maternal plant protein intake and prenatal growth and birthweight, with effect estimates close to zero. In conclusion, maternal animal protein intake during the periconception period was positively associated with early and late prenatal growth and birthweight, while no associations were found between maternal plant protein intake and prenatal growth and birthweight.
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Dissertations / Theses on the topic "Periconception period"

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Rattanatray, Leewen. "The impact of maternal overnutrition during the periconceptional period on the development of postnatal obesity in the sheep." Thesis, 2010. http://hdl.handle.net/2440/63375.

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Women who enter pregnancy with an increased body weight have an increased risk of developing gestational diabetes later in pregnancy and of having a baby with a high birth weight and fat mass who is also at an increased risk of becoming overweight or obese in childhood or later adult life. It is not known, however, whether exposure of the oocyte and embryo during the periconceptional period alone to maternal obesity is associated with an increased risk of obesity in the offspring, and if so, whether the impact of maternal obesity can be ameliorated by maternal weight loss immediately before conception. The present study has investigated in sheep, whether, a high plane of maternal nutrition before and immediately after conception leads to the programming of an increased expression of adipogenic and lipogenic genes and fat mass in the offspring and whether a period of dietary restriction in overnourished mothers reverses these changes. Non pregnant ewes (n=23) were randomly assigned to one of four treatment groups, either control-control (CC) maintained at 100% maintenance energy requirements (MER) for at least 5 months prior to conception, control-restricted (CR) maintained at 100% MER for the first 4 months, then 1 month before conception were placed on a dietary restriction to 70% MER, high-high (HH) maintained ad libitum (170-190% MER) for 5 months prior to conception or high-restricted (HR) maintained at ad libitum for 4 months, and then 1 month before conception were placed on an energy-restricted diet (70% MER). To determine the effect of overnutrition in the periconceptional period only, single embryos were then transferred to recipient ewes which were maintained on a control diet (100% MER) for the remainder of pregnancy. All ewes were allowed to give birth naturally. At 4 months of age, lamb fat depots were weighed and samples collected for the measurement of mRNA expression for genes regulating adipogenesis and lipogenesis by quantitative real-time PCR. The studies in this thesis have shown that periconceptional overnutrition increased total fat mass in female lambs at 4 months of age. This change was not associated with an increase in peroxisome proliferator-activated receptor γ, leptin or adiponectin expression in the perirenal, omental and subcutaneous fat depots. The period of dietary restriction in overnourished ewes ablated this effect. These findings suggest that the effects of periconceptional overnutrition on the oocyte or early embryo alters the subsequent development of adipose tissue, and that the impact of periconceptional overnutrition may be reduced by a period of dietary restriction prior to entering pregnancy.
Thesis (Ph.D.) -- University of Adelaide, School of Molecular and Biomedical Science, 2010
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Gomes, Sandra Cristina da Silva. "Folate intake and folic acid supplementation in the periconceptional period: recommendations and real intake." Master's thesis, 2014. https://repositorio-aberto.up.pt/handle/10216/72462.

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Gomes, Sandra Cristina da Silva. "Folate intake and folic acid supplementation in the periconceptional period: recommendations and real intake." Dissertação, 2013. https://repositorio-aberto.up.pt/handle/10216/72462.

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Book chapters on the topic "Periconception period"

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Amoako, Akwasi A., Tamer M. Nafee, and Bolarinde Ola. "Epigenetic Influences During the Periconception Period and Assisted Reproduction." In Periconception in Physiology and Medicine, 15–39. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-62414-3_2.

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Rizos, Dimitrios, Veronica Maillo, Maria-Jesús Sánchez-Calabuig, and Patrick Lonergan. "The Consequences of Maternal-Embryonic Cross Talk During the Periconception Period on Subsequent Embryonic Development." In Periconception in Physiology and Medicine, 69–86. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-62414-3_4.

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Fleming, Tom P., Judith J. Eckert, and Oleg Denisenko. "The Role of Maternal Nutrition During the Periconceptional Period and Its Effect on Offspring Phenotype." In Periconception in Physiology and Medicine, 87–105. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-62414-3_5.

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Van Eetvelde, Mieke, Sonia Heras, J. L. M. R. Leroy, Ann Van Soom, and Geert Opsomer. "The Importance of the Periconception Period: Immediate Effects in Cattle Breeding and in Assisted Reproduction Such as Artificial Insemination and Embryo Transfer." In Periconception in Physiology and Medicine, 41–68. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-62414-3_3.

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Ord, James, Alireza Fazeli, and Penelope J. Watt. "Long-Term Effects of the Periconception Period on Embryo Epigenetic Profile and Phenotype: The Role of Stress and How This Effect Is Mediated." In Periconception in Physiology and Medicine, 117–35. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-62414-3_7.

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Cetin, I., M. Massari, and F. Parisi. "17. Role of micronutrients in the periconceptional period." In Handbook of diet and nutrition in the menstrual cycle, periconception and fertility, 271–92. The Netherlands: Wageningen Academic Publishers, 2014. http://dx.doi.org/10.3920/978-90-8686-767-7_17.

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Lucas, Emma S., and Adam J. Watkins. "The Long-Term Effects of the Periconceptional Period on Embryo Epigenetic Profile and Phenotype; The Paternal Role and His Contribution, and How Males Can Affect Offspring’s Phenotype/Epigenetic Profile." In Periconception in Physiology and Medicine, 137–54. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-62414-3_8.

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Fischer, Bernd, Maria Schindler, S. Mareike Pendzialek, Jacqueline Gürke, Elisa Haucke, Katarzyna Joanna Grybel, René Thieme, and Anne Navarrete Santos. "The Long-Term Effect of the Periconception Period on the Embryo’s Epigenetic Profile and Phenotype: The Role of Maternal Disease Such as Diabetes and How the Effect Is Mediated (Example from a Rabbit Model)." In Periconception in Physiology and Medicine, 107–15. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-62414-3_6.

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Bay, Jacquie, Delaney Yaqona, and Masahito Oyamada. "DOHaD Interventions: Opportunities During Adolescence and the Periconceptional Period." In Current Topics in Environmental Health and Preventive Medicine, 37–51. Singapore: Springer Singapore, 2018. http://dx.doi.org/10.1007/978-981-13-2194-8_3.

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Nicholas, L. M., and I. C. McMillen. "The Impact of Maternal Obesity and Weight Loss During the Periconceptional Period on Offspring Metabolism." In Parental Obesity: Intergenerational Programming and Consequences, 133–61. New York, NY: Springer New York, 2016. http://dx.doi.org/10.1007/978-1-4939-6386-7_7.

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