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1

Axel, Leon. "Cerebral Perfusion CT Techniques." Radiology 233, no. 3 (December 2004): 935. http://dx.doi.org/10.1148/radiol.2333040946.

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2

Burg, Maurice B., and Mark A. Knepper. "Single tubule perfusion techniques." Kidney International 30, no. 2 (August 1986): 166–70. http://dx.doi.org/10.1038/ki.1986.168.

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3

Shann, Kenneth, and Serguei Melnitchouk. "Advances in Perfusion Techniques." Seminars in Cardiothoracic and Vascular Anesthesia 18, no. 2 (April 21, 2014): 146–52. http://dx.doi.org/10.1177/1089253214530519.

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4

Kress, R., and R. Roemer. "A Comparative Analysis of Thermal Blood Perfusion Measurement Techniques." Journal of Biomechanical Engineering 109, no. 3 (August 1, 1987): 218–25. http://dx.doi.org/10.1115/1.3138672.

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The object of this study was to devise a unified method for comparing different thermal techniques for the estimation of blood perfusion rates and to perform a comparison for several common techniques. The approach used was to develop analytical models for the temperature response for all combinations of five power deposition geometries (spherical, one- and two-dimensional cylindrical, and one- and two-dimensional Gaussian) and three transient heating techniques (temperature pulse-decay, temperature step function, and constant-power heat-up) plus one steady-state heating technique. The transient models were used to determine the range of times (the time window) when a significant portion of the transient temperature response was due to blood perfusion. This time window was defined to begin when the difference between the conduction-only and the conduction-plus-blood flow transient temperature (or power) responses exceeded a specified value, and to end when the conduction-plus-blood flow transient temperature (or power) reached a specified fraction of its steady-state value. The results are summarized in dimensionless plots showing the size of the time windows for each of the transient perfusion estimation techniques. Several conclusions were drawn, in particular: (a) low perfusions are difficult to estimate because of the dominance of conduction, (b) large heated regions are better suited for estimation of low perfusions, (c) noninvasive heating techniques are superior because they have the potential to minimize conduction effects, and (d) none of the transient techniques appears to be clearly superior to the others.
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5

Patel, Mahesh R., Bettina Siewert, Steven Warach, and Robert R. Edelman. "DIFFUSION AND PERFUSION IMAGING TECHNIQUES." Magnetic Resonance Imaging Clinics of North America 3, no. 3 (August 1995): 425–38. http://dx.doi.org/10.1016/s1064-9689(21)00254-3.

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6

Gibbons, R. J. "IMAGING TECHNIQUES: Myocardial perfusion imaging." Heart 83, no. 3 (March 1, 2000): 355–60. http://dx.doi.org/10.1136/heart.83.3.355.

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7

Guzmán-de-Villoria, J. A., P. Fernández-García, J. M. Mateos-Pérez, and M. Desco. "Studying cerebral perfusion using magnetic susceptibility techniques: Technique and applications." Radiología (English Edition) 54, no. 3 (May 2012): 208–20. http://dx.doi.org/10.1016/j.rxeng.2011.06.004.

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8

Hopkins, Susan R., Mark O. Wielpütz, and Hans-Ulrich Kauczor. "Imaging lung perfusion." Journal of Applied Physiology 113, no. 2 (July 15, 2012): 328–39. http://dx.doi.org/10.1152/japplphysiol.00320.2012.

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From the first measurements of the distribution of pulmonary blood flow using radioactive tracers by West and colleagues ( J Clin Invest 40: 1–12, 1961) allowing gravitational differences in pulmonary blood flow to be described, the imaging of pulmonary blood flow has made considerable progress. The researcher employing modern imaging techniques now has the choice of several techniques, including magnetic resonance imaging (MRI), computerized tomography (CT), positron emission tomography (PET), and single photon emission computed tomography (SPECT). These techniques differ in several important ways: the resolution of the measurement, the type of contrast or tag used to image flow, and the amount of ionizing radiation associated with each measurement. In addition, the techniques vary in what is actually measured, whether it is capillary perfusion such as with PET and SPECT, or larger vessel information in addition to capillary perfusion such as with MRI and CT. Combined, these issues affect quantification and interpretation of data as well as the type of experiments possible using different techniques. The goal of this review is to give an overview of the techniques most commonly in use for physiological experiments along with the issues unique to each technique.
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9

Tisone, G., G. Vennarecci, L. Baiocchi, S. Negrini, G. P. Palmieri, M. Angelico, M. Dauri, and C. U. Casciani. "Randomized study on in situ liver perfusion techniques: Gravity perfusion VS high-pressure perfusion." Transplantation Proceedings 29, no. 8 (December 1997): 3460–62. http://dx.doi.org/10.1016/s0041-1345(97)00978-0.

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10

Kim, E. E. "Clinical Perfusion MRI: Techniques and Applications." Journal of Nuclear Medicine 55, no. 3 (February 10, 2014): 522. http://dx.doi.org/10.2967/jnumed.114.138172.

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11

Ganushchak, Yuri, and Peyman Sardari Nia. "Perfusion techniques in minimally invasive setting." Journal of Visualized Surgery 4 (December 2018): 250. http://dx.doi.org/10.21037/jovs.2018.12.04.

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12

Pappa, Maria D., Nikolaos V. Theodosiadis, Dimitrios Paliouras, Thomas Rallis, Apostolos S. Gogakos, Nikolaos Barbetakis, Fotios Chatzinikolaou, et al. "Advanced Perfusion Techniques - Flow versus Pressure." Journal of Biomedicine 2 (2017): 20–24. http://dx.doi.org/10.7150/jbm.17864.

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13

Aneman, A., D. Burgener, M. Svensson, Y. Oi, and A. Hadengue. "Evaluation of intestinal perfusion monitoring techniques." Critical Care 3, Suppl 1 (1999): P166. http://dx.doi.org/10.1186/cc539.

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14

Gooris, T., G. Van Vaerenbergh, J. Coddens, S. Bouchez, and H. Vanermen. "Perfusion techniques for port-access surgery." Perfusion 13, no. 4 (July 1998): 243–47. http://dx.doi.org/10.1177/026765919801300406.

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15

Eyding, Jens, Wilko Wilkening, and Thomas Postert. "Brain perfusion and ultrasonic imaging techniques." European Journal of Ultrasound 16, no. 1-2 (November 2002): 91–104. http://dx.doi.org/10.1016/s0929-8266(02)00042-3.

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16

Krishnan, Pradeep, Amanda Murphy, and Richard I. Aviv. "CT-based Techniques for Brain Perfusion." Topics in Magnetic Resonance Imaging 26, no. 3 (June 2017): 113–19. http://dx.doi.org/10.1097/rmr.0000000000000129.

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17

Stretch, Graham L., Roger L. Nation, Allan M. Evans, and Robert W. Milne. "Organ perfusion techniques in drug development." Drug Development Research 46, no. 3-4 (March 1999): 292–301. http://dx.doi.org/10.1002/(sici)1098-2299(199903/04)46:3/4<292::aid-ddr15>3.0.co;2-4.

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18

Uz, Zühre, Lucinda Shen, Dan M. J. Milstein, Krijn P. van Lienden, Rutger-Jan Swijnenburg, Can Ince, and Thomas M. van Gulik. "Intraoperative Imaging Techniques to Visualize Hepatic (Micro)Perfusion: An Overview." European Surgical Research 61, no. 1 (2020): 2–13. http://dx.doi.org/10.1159/000508348.

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The microcirculation plays a crucial role in the distribution of perfusion to organs. Studies have shown that microcirculatory dysfunction is an independent predictor of morbidity and mortality. Hence, assessment of liver perfusion offers valuable information on the (patho)physiological state of the liver. The current review explores techniques in perfusion imaging that can be used intraoperatively. Available modalities include dynamic contrast-enhanced ultrasound, handheld vital microscopes, indocyanine green fluorescence angiography, and laser contrast speckle imaging. Dynamic contrast-enhanced ultrasound relays information on deep tissue perfusion and is a commonly used technique to assess tumor perfusion. Handheld vital microscopes provide direct visualization of the sinusoidal architectural structure of the liver, which is a unique feature of this technique. Intraoperative fluorescence imaging uses indocyanine green, a dye that is administered intravenously to visualize microvascular perfusion when excited using near-infrared light. Laser speckle contrast imaging produces non-contact large surface-based tissue perfusion imaging free from movement- or pressure-related artefacts. In this review, we discuss the intrinsic advantages and disadvantages of these techniques and their clinical and/or scientific applications.
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19

Jáni, Laura, Lehel Bordi, Mirabela Morariu, Tiberiu Nyulas, István Kovács, Annabell Benedek, and Imre Benedek. "Imaging Techniques for the Assessment of Myocardial Perfusion." Journal of Interdisciplinary Medicine 1, no. 3 (December 1, 2016): 247–51. http://dx.doi.org/10.1515/jim-2016-0069.

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Abstract One of the most significant causes of heart failure is coronary heart disease and subsequent left ventricular dysfunction. The prognosis and perioperative mortality are influenced by left ventricular function, which is also an important predictor marker following revascularization. The evaluation of myocardial perfusion is of utmost importance in patients who present several symptoms before choosing cardiac catheterization as treatment. The evaluation of myocardial perfusion and myocardial viability leads to superior diagnostic and treatment algorithms, thus resulting in an important improvement in the outcomes of patients with coronary artery disease. Color Doppler myocardial imaging, single-photon emission computed tomography (SPECT), contrast perfusion echocardiography, positron emission computed tomography (PET) and magnetic resonance imaging (MRI) are currently used methods for assessing myocardial perfusion. This review aims to summarize the benefits and disadvantages of each of these techniques.
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20

Raskin, Steven A., and Joseph S. Coselli. "Retrograde cerebral perfusion: overview, techniques and results." Perfusion 10, no. 1 (January 1995): 51–57. http://dx.doi.org/10.1177/026765919501000109.

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Cardiovascular surgical repair of arch aneurysms is taking a step forward by going backwards by utilizing retrograde cerebral perfusion. Drs ME DeBakey, ES Crawford, DA Cooley and GC Morris first reported successful resection and repair of a fusiform aneurysm of the aortic arch with replacement graft in 1957.1 Since then, Crawford and Coselli have pursued materials and techniques which have made this procedure, one which generally resulted in high morbidity and mortality, more viable with decreased morbidity and mortality. Increased numbers of patients are now having this repair and are resuming normal healthy lives after the operation. From February 1992 to October 1993, 88 patients were surgically treated by Coselli who utilized retrograde cerebral perfusion with profound hypothermia and circulatory arrest, thus allowing for repairs that under any other conditions probably could not have been achieved successfully. It is evident that a major determinant for the successful clinical results, in addition to surgical technique and skill, was the employment of profound hypothermia and circulatory arrest. This article will review the techniques and results of aortic arch repair utilizing retrograde cerebral perfusion during circulatory arrest with profound hypothermia to lessen the chance of neurological morbidity following surgical replacement of the transverse aortic arch.
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21

de Jong, A., BA Popa, E. Stelian, L. Karazanishvili, G. Lanzillo, S. Simonini, L. Renzi, M. Diena, and UF Tesler. "Perfusion techniques for minimally invasive valve procedures." Perfusion 30, no. 4 (October 3, 2014): 270–76. http://dx.doi.org/10.1177/0267659114550326.

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22

Wintermark, Max, Musa Sesay, Emmanuel Barbier, Katalin Borbély, William P. Dillon, James D. Eastwood, Thomas C. Glenn, et al. "Comparative Overview of Brain Perfusion Imaging Techniques." Stroke 36, no. 9 (September 2005): 2032–33. http://dx.doi.org/10.1161/01.str.0000177839.03321.25.

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23

Maack, Thomas. "Renal clearance and isolated kidney perfusion techniques." Kidney International 30, no. 2 (August 1986): 142–51. http://dx.doi.org/10.1038/ki.1986.166.

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24

Kestelli, M., I. Yurekli, M. Akyuz, and B. Ozcem. "Are all antegrade cerebral perfusion techniques equal?" European Journal of Cardio-Thoracic Surgery 41, no. 6 (January 6, 2012): 1406. http://dx.doi.org/10.1093/ejcts/ezr218.

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25

Wintermark, M., M. Sesay, E. Barbier, K. Borbély, W. P. Dillon, J. D. Eastwood, T. C. Glenn, et al. "Comparative overview of brain perfusion imaging techniques." Journal of Neuroradiology 32, no. 5 (December 2005): 294–314. http://dx.doi.org/10.1016/s0150-9861(05)83159-1.

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26

Doppman, J. L., R. L. Dedrick, D. R. Shook, R. J. Lutz, S. R. Goldstein, J. B. Blacklock, J. W. Boretos, R. H. Paul, H. A. Austin, and R. L. Bowman. "Glioblastoma: catheter techniques for isolated chemotherapy perfusion." Radiology 159, no. 2 (May 1986): 477–83. http://dx.doi.org/10.1148/radiology.159.2.3961181.

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27

Wu, Ying-ying, Yu Ban, Ning Geng, Yong-yue Wang, Xiao-guang Liu, Tao Yu, and Ping Gong. "Evaluation of different culture techniques of osteoblasts on 3D scaffolds." Open Life Sciences 5, no. 4 (August 1, 2010): 456–65. http://dx.doi.org/10.2478/s11535-010-0027-z.

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AbstractBones adjust their structure to withstand the mechanical demands they experience. It is suggested that flow-derived shear stress may be the most significant and primary mediator of mechanical stimulation. In this study, we designed and fabricated a fluid flow cell culture system that can load shear stress onto cells cultured on 3D scaffolds. We evaluated the effect of different culture techniques, namely, (1) continuous perfusion fluid flow, (2) intermittent perfusion fluid flow, and (3) static condition, on the proliferation of osteoblasts seeded on partially deproteinized bones. The flow rate was set at 1 ml/min for all the cells cultured using flow perfusion and the experiment was conducted for 12 days. Scanning electron microscopy analysis indicated an increase in cell proliferation for scaffolds subjected to fluid shear stress. In addition, the long axes of these cells lengthened along the flowing fluid direction. Continuous perfusion significantly enhanced cell proliferation compared to either intermittent perfusion or static condition. All the results demonstrated that fluid shear stress is able to enhance the proliferation of cells and change the form of cells.
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28

Tchervenkov, Christo I., Abdulaziz Al-Khaldi, and Dominique Shum-Tim. "Antegrade regional cerebral perfusion." Cardiology in the Young 14, S1 (February 2004): 70–74. http://dx.doi.org/10.1017/s104795110400633x.

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A quiet and bloodless field providing optimal surgical conditions has been a crucial prerequisite for the performance of complex cardiac repairs in early life. The use of deep hypothermic circulatory arrest has fulfilled this role, and has been a catalyst for the development of neonatal and infant cardiac surgery. The recently increased awareness of possibly increased incidence of adverse neurological events and developmental outcome associated with this technique,1–5however, has led to a general trend away from its use. In its place, techniques have been developed to provide cerebral perfusion during reconstruction of the aortic arch and the Norwood operation. Some have described the techniques as regional low-flow perfusion. In our opinion, they are described more accurately as antegrade regional cerebral perfusion. In this review, we discuss the recently described techniques for such antegrade regional cerebral perfusion during surgery on the aortic arch, with emphasis both on the Norwood operation and the observed physiological changes in the cerebral and systemic circulations. The neurologic and developmental outcomes following the use of the technique are still unknown.
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29

Fathala, Ahmed. "Myocardial Perfusion Scintigraphy: Techniques, Interpretation, Indications and Reporting." Annals of Saudi Medicine 31, no. 6 (November 2011): 625–34. http://dx.doi.org/10.4103/0256-4947.87101.

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30

Borges-Neto, Salvador. "Perfusion and function assessment by nuclear cardiology techniques." Current Opinion in Cardiology 12, no. 6 (November 1997): 581–86. http://dx.doi.org/10.1097/00001573-199711000-00013.

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31

Villemain, Olivier, Jérôme Baranger, Zakaria Jalal, Christopher Lam, Jérémie Calais, Mathieu Pernot, Barbara Cifra, Mark K. Friedberg, and Luc Mertens. "Non-invasive imaging techniques to assess myocardial perfusion." Expert Review of Medical Devices 17, no. 11 (October 22, 2020): 1133–44. http://dx.doi.org/10.1080/17434440.2020.1834844.

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32

Carsin, M., J. C. Ferré, B. Carsin-Nicol, G. Hérigault, and J. Y. Gauvrit. "Evolution des techniques de perfusion cerebrale a 3T." Journal de Radiologie 88, no. 10 (October 2007): 1272. http://dx.doi.org/10.1016/s0221-0363(07)80646-9.

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33

Barnard, Michele L. "Perfusion Techniques for Determining Alveolar Fluid Resorption Rate." Journal of Applied Physiology 86, no. 5 (May 1, 1999): 1749–50. http://dx.doi.org/10.1152/jappl.1999.86.5.1749.

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34

Gupta, Vikas, Hortense A. Kirişli, Emile A. Hendriks, Rob J. van der Geest, Martijn van de Giessen, Wiro Niessen, Johan H. C. Reiber, and Boudewijn P. F. Lelieveldt. "Cardiac MR perfusion image processing techniques: A survey." Medical Image Analysis 16, no. 4 (May 2012): 767–85. http://dx.doi.org/10.1016/j.media.2011.12.005.

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35

Wesbey, George, and David Haynor. "Using NMR diffusion techniques to measure tissue perfusion." Magnetic Resonance Imaging 3, no. 3 (January 1985): 302–3. http://dx.doi.org/10.1016/0730-725x(85)90364-9.

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36

Simpson, D. H., P. N. Burns, and M. A. Averkiou. "Techniques for perfusion imaging with microbubble contrast agents." IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control 48, no. 6 (2001): 1483–94. http://dx.doi.org/10.1109/58.971698.

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37

Zaid Al-Kaylani, Abdallah H. A., Richte C. L. Schuurmann, Wouter D. Maathuis, Riemer H. J. A. Slart, Jean-Paul P. M. De Vries, and Reinoud P. H. Bokkers. "Clinical Applications of Quantitative Perfusion Imaging with a C-Arm Flat-Panel Detector—A Systematic Review." Diagnostics 13, no. 1 (December 30, 2022): 128. http://dx.doi.org/10.3390/diagnostics13010128.

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C-arm systems with digital flat-panel detectors are used in interventional radiology and hybrid operating rooms for visualizing and performing interventions on three-dimensional structures. Advances in C-arm technology have enabled intraoperative quantitative perfusion imaging with these scanners. This systematic review provides an overview of flat-panel detector C-arm techniques for quantifying perfusion, their clinical applications, and their validation. A systematic search was performed for articles published between January 2000 and October 2022 in which a flat-panel detector C-arm technique for quantifying perfusion was compared with a reference technique. Nine articles were retrieved describing two techniques: two-dimensional perfusion angiography (n = 5) and dual-phase cone beam computed tomography perfusion (n = 4). A quality assessment revealed no concerns about the applicability of the studies. The risk of bias was relatively high for the index and reference tests. Both techniques demonstrated potential for clinical application; however, weak-to-moderate correlations were reported between them and the reference techniques. In conclusion, both techniques could add new possibilities to treatment planning and follow-up; however, the available literature is relatively scarce and heterogeneous. Larger-scale randomized prospective studies focusing on clinical outcomes and standardization are required for the full understanding and clinical implementation of these techniques.
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38

van Haren, F. M. P., J. W. Sleigh, R. Pickkers, and J. G. Van Der Hoeven. "Gastrointestinal Perfusion in Septic Shock." Anaesthesia and Intensive Care 35, no. 5 (October 2007): 679–94. http://dx.doi.org/10.1177/0310057x0703500505.

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Septic shock is characterised by vasodilation, myocardial depression and impaired microcirculatory blood flow, resulting in redistribution of regional blood flow. Animal and human studies have shown that gastrointestinal mucosal blood flow is impaired in septic shock. This is consistent with abnormalities found in many other microcirculatory vascular beds. Gastrointestinal mucosal microcirculatory perfusion deficits have been associated with gut injury and a decrease in gut barrier function, possibly causing augmentation of systemic inflammation and distant organ dysfunction. A range of techniques have been developed and used to quantify these gastrointestinal perfusion abnormalities. The following techniques have been used to study gastrointestinal perfusion in humans: tonometry, laser Doppler flowmetry reflectance spectrophotometry, near-infrared spectroscopy, orthogonal polarisation spectral imaging, indocyanine green clearance, hepatic vein catheterisation and measurements of plasma D-lactate. Although these methods share the ability to predict outcome in septic shock patients, it is important to emphasise that the measurement results are not interchangeable. Different techniques measure different elements of gastrointestinal perfusion. Gastric tonometry is currently the most widely used technique because of its non-invasiveness and ease of use. Despite all the recent advances, the usefulness of gastrointestinal perfusion parameters in clinical decision-making is still limited. Treatment strategies specifically aimed at improving gastrointestinal perfusion have failed to actually correct mucosal perfusion abnormalities and hence not shown to improve important clinical endpoints. Current and future treatment strategies for septic shock should be tested for their effects on gastrointestinal perfusion; to further clarify its exact role in patient management, and to prevent therapies detrimental to gastrointestinal perfusion being implemented.
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39

Thomassin-Naggara, I., D. Balvay, A. Rockall, M. F. Carette, M. Ballester, E. Darai, and M. Bazot. "Added Value of Assessing Adnexal Masses with Advanced MRI Techniques." BioMed Research International 2015 (2015): 1–10. http://dx.doi.org/10.1155/2015/785206.

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This review will present the added value of perfusion and diffusion MR sequences to characterize adnexal masses. These two functional MR techniques are readily available in routine clinical practice. We will describe the acquisition parameters and a method of analysis to optimize their added value compared with conventional images. We will then propose a model of interpretation that combines the anatomical and morphological information from conventional MRI sequences with the functional information provided by perfusion and diffusion weighted sequences.
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40

Bonen, A., M. G. Clark, and E. J. Henriksen. "Experimental approaches in muscle metabolism: hindlimb perfusion and isolated muscle incubations." American Journal of Physiology-Endocrinology and Metabolism 266, no. 1 (January 1, 1994): E1—E16. http://dx.doi.org/10.1152/ajpendo.1994.266.1.e1.

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The perfusion of rat hindlimb muscles and the isolated in vitro muscle preparation are usually the preferred methods for investigating muscle metabolism. In light of recent concerns about the incubated muscle preparation, we have examined the problems, the advantages, and the viability of these two experimental techniques, with focus on glucose metabolism. A major advantage of the hindlimb perfusion system is that it maintains its metabolic viability very well, and perfusions in resting muscles can be achieved successfully with cell-free media. However, variations in the perfused rat hindlimb procedures result in considerable differences in perfusate flow among muscles, making quantitative comparisons among perfusion procedures difficult. Metabolic viability has been identified as a problem in some isolated in vitro muscle preparations. We have provided criteria to avoid muscle hypoxia. Minimum levels of insulin seem to be a key requirement to maintaining the muscle's viability, and essential amino acids are required to retard an increase in the basal rate of glucose and amino acid uptake. Under such conditions metabolic viability can be maintained during prolonged incubations (9-30 h). Both the isolated in vitro muscle preparation and the hindlimb perfusion preparation are viable models for the study of muscle metabolism.
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41

Lad, Shivanand P., Raphael Guzman, Michael E. Kelly, Gordon Li, Michael Lim, Karl Lovbald, and Gary K. Steinberg. "Cerebral perfusion imaging in vasospasm." Neurosurgical Focus 21, no. 3 (September 2006): 1–9. http://dx.doi.org/10.3171/foc.2006.21.3.7.

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✓Vasospasm following cerebral aneurysm rupture is one of the most devastating sequelae and the most common cause of delayed ischemic neurological deficit (DIND). Because vasospasm also is the most common cause of morbidity and mortality in patients who survive the initial bleeding episode, it is imperative not only to diagnose the condition but also to predict which patients are likely to become symptomatic. The exact pathophysiology of vasospasm is complex and incompletely elucidated. Early recognition of vasospasm is essential because the timely use of several therapeutic interventions can counteract this disease and prevent the occurrence of DIND. However, the prompt implementation of these therapies depends on the ability to predict impending vasospasm or to diagnose it at its early stages. A number of techniques have been developed during the past several decades to evaluate cerebral perfusion, including positron emission tomography, xenon-enhanced computed tomography, single-photon emission computed tomography, perfusion- and diffusion-weighted magnetic resonance imaging, and perfusion computed tomography. In this article, the authors provide a general overview of the currently available perfusion imaging techniques and their applications in treating vasospasm after a patient has suffered a subarachnoid hemorrhage. The use of cerebral perfusion imaging techniques for the early detection of vasospasm is becoming more common and may provide opportunities for early therapeutic intervention to counteract vasospasm in its earliest stages and prevent the occurrence of DINDs.
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42

Rozen, Warren M., Rachael Leung, Michael P. Chae, and David J. Hunter-Smith. "Imaging of perforasome territories: the evolution of techniques." Australasian Journal of Plastic Surgery 1, no. 2 (September 24, 2018): 65–73. http://dx.doi.org/10.34239/ajops.v1i2.121.

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Background: Perforator flaps are widely used in reconstructive plastic surgery and technological advances in preoperative imaging have facilitated improvements in flap perfusion and clinical outcomes. The ‘perforasome’ concept describes the vascular territory supplied by a single arterial perforator and the imaging of these zones of perfusion has become increasingly advanced. Methods: This paper presents a qualitative analysis of the current literature on perforasome imaging. A review of the literature was performed using PubMed and Medline. Historical and background studies were also included for completeness. Results: The review identified an initial 858 records for assessment, with 52 studies formally reviewed. To date, there is largely level III and IV evidence for the available imaging techniques, although level II studies are emerging. There is currently no level I evidence for any imaging technique. Conclusion: There have been significant developments in imaging techniques since the introduction of the perforasome concept nearly a decade ago. In this review we have described the evolution of these methods over time, from simple perforator location to advanced three- and four-dimensional imaging and real-time dynamic perfusion imaging. With this progression and ongoing innovation, we believe perforasome imaging has the potential to improve outcomes in perforator flap surgery.
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43

Ben-Hamouda, N., and M. Oddo. "Monitorage cérébral après arrêt cardiaque : techniques et utilité clinique potentielle." Médecine Intensive Réanimation 28, no. 5 (December 24, 2018): 389–97. http://dx.doi.org/10.3166/rea-2018-0082.

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L’arrêt cardiaque cause une hypoxie-ischémie globale, suivi de reperfusion, qui est susceptible d’engendrer des effets délétères sur la perfusion et l’oxygénation cérébrales, ainsi que le métabolisme cellulaire. Dans ce contexte, et en l’absence de thérapies spcéfiques de l’ischémie-reperfusion globale, le traitement est essentiellement de soutien, visant à optimiser la perfusion et l’oxygénation cérébrale, dans le but de prévenir ou atténuer les dégâts secondaires sur la fonction cérébrale. Dans ce contexte, le monitorage cérébral multimodal, notamment les techniques non-invasives, ont une utilité potentielle à la phase agiuë de l’arrêt cardiaque. Le but prinicpal de cette revue est de décrire les techniques actuellement dipsonibles, en nous focalisant surtout sur les outils noninvasifs (doppler transcranien, spectrospcope de proche infrarouge, électroencéphalographie, pupillométrie automatisée proche infrarouge), leur utilité clinique potentielle ainsi que leurs limitations, dans la prise en charge aiguë (optimisation de la perfusion et de l’oxygénation cérébrales) ainsi que pour la détermination du pronostic précoce après arrêt cardiaque.
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44

Vertrees, Roger A., Joseph B. Zwischenberger, Lee C. Woodson, Eric A. Bedell, Donald J. Deyo, and Jill M. Chernin. "Veno-venous perfusion-induced systemic hyperthermia: case report with perfusion considerations." Perfusion 16, no. 3 (May 2001): 243–48. http://dx.doi.org/10.1177/026765910101600310.

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Cancer cells are more susceptible to destruction by heat than are their normal counterparts. However, optimization of this hyperthermic susceptibility for selective cancer cell kill has been difficult to define and technically difficult to achieve. A whole-body hyperthermic technique - veno-venous perfusion-induced systemic hyperthermia (VV-PISH) was designed in in vitro and in swine experiments to achieve selective hyperthermic cancer cell destruction. In this case report, VV-PISH is studied for its safety and therapeutic efficiency in a Food and Drug Administration (FDA) approved phase-I study, where hyperthermia is used to treat advanced (Stage III B or IV) lung cancer. VV-PISH, utilizing the ThermoChem™ HT system in an extracorporeal circuit, was used to induce hyperthermia to 42.5°C sustained for 120 min. Cooling returned the body temperature to 37°C. After completion of the treatment, the patient was transferred to the intensive care unit on a ventilator, norepinephrine and diuretics. The patient remained somnolent for 36 h, developed pulmonary congestion requiring an additional 48 h before extubation, was transferred to the intermediate unit on day 4 and discharged in good condition on day 8. He did experience hyperthermia-related shrinkage of his lung cancer; however, he succumbed 270 days after this treatment from further progression of this disease. Hyperthermia is not a benign therapy; management techniques have been developed that have ameliorated many of the problems associated with extremely high temperatures, but pathophysiology still exists. Using these techniques, VV-PISH can be safety implemented, albeit not without temporary sequelae and further hospitalization.
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Pegg, D. E., R. Y. Calne, J. Pryse-davies, and Fiona Leigh Brown. "canine renal preservation using surface and perfusion cooling techniques*." Annals of the New York Academy of Sciences 120, no. 2 (December 16, 2006): 506–23. http://dx.doi.org/10.1111/j.1749-6632.1965.tb30680.x.

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46

Smulowitz, Peter B., Dan L. Serna, Gerald E. Beckham, and Jeffrey C. Milliken. "Ex Vivo Cardiac Allograft Preservation by Continuous Perfusion Techniques." ASAIO Journal 46, no. 4 (July 2000): 389–96. http://dx.doi.org/10.1097/00002480-200007000-00004.

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47

Croisille, P. "Cardiopathies ischémiques (perfusion myocardique et viabilité) : techniques et résultats." Journal de Radiologie 85, no. 10 (October 2004): 1811–18. http://dx.doi.org/10.1016/s0221-0363(04)97752-9.

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Croisille, P. "Cardiopathies ischémiques (perfusion myocardique et viabilité) : techniques et résultats." Journal de Radiologie 85, no. 10 (October 2004): 1819–20. http://dx.doi.org/10.1016/s0221-0363(04)97753-0.

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49

Pegg, D. E., R. Y. Calne, J. Pryse-Davies, and Fiona Leigh Brown. "CANINE RENAL PRESERVATION USING SURFACE AND PERFUSION COOLING TECHNIQUES*." Annals of the New York Academy of Sciences 120, no. 1 (December 16, 2006): 506–23. http://dx.doi.org/10.1111/j.1749-6632.1964.tb34748.x.

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Aldea, G. "After biocompatibility and advances in perfusion techniques and technologies." ITBM-RBM 23 (October 2002): 27–28. http://dx.doi.org/10.1016/s1297-9562(02)80040-7.

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