Academic literature on the topic 'PDMS Replica molding'

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Journal articles on the topic "PDMS Replica molding"

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Huang, Chiung Fang, Jeol Long Lee, Yung Kang Shen, Chi Wei Wu, Yi Lin, Sung Chih Hsu, Ming Wei Wu, and Chung Yu Kao. "Analysis for Replication and Surface Roughness of Micro-Feature of Silicon Mold Insert by UV-LIGA Method." Advanced Materials Research 47-50 (June 2008): 443–46. http://dx.doi.org/10.4028/www.scientific.net/amr.47-50.443.

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This study demonstrates the replication property and surface roughness for metal micro-mold that combines the replica molding (REM) and electroforming techniques. The micro-mold firstly uses the silicon wafer to fabricate the master mold by UV-LIGA method, and then uses the sputtering method to sputter the Ni element as the seed layer on the surface of master mold. The electroforming method manufactures the Ni mold insert from the master mold with seed layer. Finally, this study uses the PDMS material to replicate the micro-feature from the Ni mold insert by replica molding. This study indicates the replication property and surface roughness of different micro-feature shapes and sizes (concave and convex) for Ni mold insert and molded PDMS.
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Li, Kan, Yaokang Zhang, Hongyu Zhen, Helin Wang, Shenghua Liu, Feng Yan, and Zijian Zheng. "Versatile biomimetic haze films for efficiency enhancement of photovoltaic devices." Journal of Materials Chemistry A 5, no. 3 (2017): 969–74. http://dx.doi.org/10.1039/c6ta07586j.

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Willems, Stan B. J., Jaccoline Zegers, Anton Bunschoten, R. Martijn Wagterveld, Fijs W. B. van Leeuwen, Aldrik H. Velders, and Vittorio Saggiomo. "COvalent monolayer patterns in Microfluidics by PLasma etching Open Technology – COMPLOT." Analyst 145, no. 5 (2020): 1629–35. http://dx.doi.org/10.1039/c9an02407g.

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Plasma microcontact patterning (PμCP) and replica molding were combined to make PDMS/glass microfluidic devices with β-cyclodextrin (β-CD) patterns attached covalently on the glass surface inside microchannels.
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Fang, Tao, Chen, Wang, Wu, Zhang, Zeng, Zhu, and Liu. "Microlens Fabrication by Replica Molding of Electro-Hydrodynamic Printing Liquid Mold." Micromachines 11, no. 2 (February 3, 2020): 161. http://dx.doi.org/10.3390/mi11020161.

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In this paper, we synergistically combine electrohydrodynamic (EHD) printing and replica molding for the fabrication of microlenses. Glycerol solution microdroplets was sprayed onto the ITO glass to form liquid mold by an EHD printing process. The liquid mold is used as a master to fabricate a polydimethylsiloxane (PDMS) mold. Finally, the desired micro-optical device can be fabricated on any substrate using a PDMS soft lithography mold. We demonstrate our strategy by generating microlenses of photocurable polymers and by characterizing their optical properties. It is a new method to rapidly and cost-effectively fabricate molds with small diameters by exploiting the advantages of EHD printing, while maintaining the parallel nature of soft-lithography.
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Shih, Teng-Kai, Chia-Fu Chen, Jeng-Rong Ho, and Fang-Tzu Chuang. "Fabrication of PDMS (polydimethylsiloxane) microlens and diffuser using replica molding." Microelectronic Engineering 83, no. 11-12 (November 2006): 2499–503. http://dx.doi.org/10.1016/j.mee.2006.05.006.

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Amadeo, Filippo, Prithviraj Mukherjee, Hua Gao, Jian Zhou, and Ian Papautsky. "Polycarbonate Masters for Soft Lithography." Micromachines 12, no. 11 (November 13, 2021): 1392. http://dx.doi.org/10.3390/mi12111392.

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Fabrication of microfluidic devices by soft lithography is by far the most popular approach due to its simplicity and low cost. The approach relies on casting of elastomers, such as polydimethylsiloxane (PDMS), on masters fabricated from photoresists on silicon substrates. These masters, however, can be expensive, complicated to fabricate, and fragile. Here we describe an optimized replica molding approach to preserve the original masters by heat molding of polycarbonate (PC) sheets on PDMS molds. The process is faster and simpler than previously reported methods and does not result in a loss of resolution or aspect ratio for the features. The generated PC masters were used to successfully replicate a wide range of microfluidic devices, including rectangular channels with aspect ratios from 0.025 to 7.3, large area spiral channels, and micropost arrays with 5 µm spacing. Moreover, fabrication of rounded features, such as semi-spherical microwells, was possible and easy. Quantitative analysis of the replicated features showed variability of <2%. The approach is low cost, does not require cleanroom setting or hazardous chemicals, and is rapid and simple. The fabricated masters are rigid and survive numerous replication cycles. Moreover, damaged or missing masters can be easily replaced by reproduction from previously cast PDMS replicas. All of these advantages make the PC masters highly desirable for long-term preservation of soft lithography masters for microfluidic devices.
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Hlúbiková, D., A. T. Luís, V. Vaché, L. Ector, L. Hoffmann, and P. Choquet. "Optimization of the replica molding process of PDMS using pennate diatoms." Journal of Micromechanics and Microengineering 22, no. 11 (September 28, 2012): 115019. http://dx.doi.org/10.1088/0960-1317/22/11/115019.

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Folch, A., A. Ayon, O. Hurtado, M. A. Schmidt, and M. Toner. "Molding of Deep Polydimethylsiloxane Microstructures for Microfluidics and Biological Applications." Journal of Biomechanical Engineering 121, no. 1 (February 1, 1999): 28–34. http://dx.doi.org/10.1115/1.2798038.

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Here we demonstrate the microfabrication of deep (>25 μm) polymeric microstructures created by replica-molding polydimethylsiloxane (PDMS) from microfabricated Si substrates. The use of PDMS structures in microfluidics and biological applications is discussed. We investigated the feasibility of two methods for the microfabrication of the Si molds: deep plasma etch of silicon-on-insulator (SOI) wafers and photolithographic patterning of a spin-coated photoplastic layer. Although the SOI wafers can be patterned at higher resolution, we found that the inexpensive photoplastic yields similar replication fidelity. The latter is mostly limited by the mechanical stability of the replicated PDMS structures. As an example, we demonstrate the selective delivery of different cell suspensions to specific locations of a tissue culture substrate resulting in micropatterns of attached cells.
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Zhang, Zhongle, Yuan Luo, Xiaofeng Nie, Duli Yu, and Xiaoxing Xing. "A one-step molded microfluidic chip featuring a two-layer silver-PDMS microelectrode for dielectrophoretic cell separation." Analyst 145, no. 16 (2020): 5603–14. http://dx.doi.org/10.1039/d0an01085e.

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Ko, Yong Jun, Dae Jin Kim, Woong Cho, Yoo Min Ahn, and Seung Yong Hwang. "Glass-Polydimethysiloxane Hybrid Microthermostat for Restriction Enzyme Digestion." Materials Science Forum 544-545 (May 2007): 335–38. http://dx.doi.org/10.4028/www.scientific.net/msf.544-545.335.

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This paper reports a low-cost microthermostat that is able to maintain a constant temperature necessary for restriction enzyme digestion. Polydimethylsiloxane (PDMS) and Pyrex glass were used to make the microthermostat, because PDMS is a cheap and mass-producible material and both PDMS and glass have very good biocompatibility compared to the more commonly used silicon. A heater made of Au wiring patterned on Pyrex glass was used to control the temperature. A PDMS replica molding technique was used to fabricate a reaction chamber with 3.6 μl capacity. Restriction enzyme digestion was performed by using the fabricated microthermostat and by a conventional method. Then, using gel electrophoresis, we compared results between the microthermostat and conventional methods. It was found that restriction enzyme digestion using the microthermostat required 5 min of heating.
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Dissertations / Theses on the topic "PDMS Replica molding"

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Kuo, Shih-Hsun, and 郭時勛. "The study of controlling pretilt angle of liquid crystal by replica molding method for fabricating the microgroove PDMS film." Thesis, 2012. http://ndltd.ncl.edu.tw/handle/47464600304537108241.

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碩士
國立中山大學
物理學系研究所
100
In this study, the PDMS with microgroove structure was used controlling pretilt anlge of liquid crystal. Polydimethylsiloxane, also called PDMS, is one transparent, flexible, and stable material. It was usually fabricated the flexible display and so on. Based on Groove Theory, we can create the microgroove structure with the different groove depths and the width of the lines on PDMS by Replica Molding Method, in order to controlling the pretilt anlge of liquid crystal. We used the photoresist with different thickness to developing, and then the groove will get with different depth of groove. The PDMS was injected to the surface of groove with slow motion. When the liquid-like PDMS was curing, the PDMS can readily convert into solid elastomers by cross-linking. Finally, The microgrooved PDMS structure will obtain.
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Conference papers on the topic "PDMS Replica molding"

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Liu, Kewei, Yoontae Kim, and Hongseok (Moses) Noh. "Excimer Laser-Machined SU-8 Microstructures for Polydimethylsiloxane (PDMS) Replica Molding." In ASME 2014 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2014. http://dx.doi.org/10.1115/imece2014-39177.

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Excimer laser ablation is considered a versatile technique to machine three-dimensional (3-D) structures which is difficult to create only by conventional microfabrication technique. We introduce the use of 193 nm excimer laser micromachining for fabrication of negative photoresist (SU-8) master molds for polydimethylsiloxane (PDMS) replica molding. Experimental characterization study on the effect of laser parameters (fluence, repetition rate, and number of shots) on the etch performances (etch rate, and aspect ratio) is presented here. Etch rate per shot of SU-8 was proportional to the fluence, but inversely proportional to the number of shots. The repetition rate of laser firing did not show a noteworthy influence to the etch rates. Aspect ratio was also proportional to the fluence and number of laser firing, but was not affected by the repetition rate of laser. For demonstration of replica molding, we made holes with different depth in SU-8 layer and used it to create PDMS micropillar array.
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Wang, Mengjiao, Cai Jun, and Zhenhu Wang. "Fabrication of Hierarchical 3D PDMS Molds by Replica Molding from Diatom Frustules." In 2018 IEEE 13th Annual International Conference on Nano/Micro Engineered and Molecular Systems (NEMS). IEEE, 2018. http://dx.doi.org/10.1109/nems.2018.8557028.

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Zeng, Hansong, Yi Zhao, Benxin Wu, Chris Taylor, Ronald L. Jacobsen, and Yibo Gao. "Picosecond Laser Ablation of Polydimethylsiloxane (PDMS)." In ASME 2009 International Manufacturing Science and Engineering Conference. ASMEDC, 2009. http://dx.doi.org/10.1115/msec2009-84338.

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Picosecond laser ablation of Polydimethylsiloxane (PDMS) has been studied experimentally. The measurements show that laser ablation rate per pulse increases with laser fluence and pulse number. The laser-drilled hole diameter increases with pulse number, and it saturates above certain pulse number for low fluence. The study shows that picosecond laser ablation may provide a good solution for micromachining PDMS, which is more flexible and versatile than the replica molding technique.
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Yang, Bozhi, George C. Lopez, Qiao Lin, and Alan J. Rosenbloom. "Microfabricated PDMS Check Valves." In ASME 2003 International Mechanical Engineering Congress and Exposition. ASMEDC, 2003. http://dx.doi.org/10.1115/imece2003-41213.

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This paper presents two types of novel micro check valves that are based on PDMS. The valves consist of a thin flap and a flow restriction block inside a microchannel. The flap is perpendicular to the flow and lies near the block, which forms a restricted fluid path inside the channel. The valves are fabricated entirely from PDMS through replica molding techniques and can be readily integrated in PDMS-based complex microfluidic systems. Testing results show that for a reverse flow, the 2D valve has a saturated leakage rate at higher pressures, leading to an interesting “fluid diode” phenomenon, while the 3D valve has zero leakage at higher pressures.
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Tooley, Wes W., Shirin Feghhi, Sangyoon J. Han, Junlan Wang, and Nathan J. Sniadecki. "Thermal Fracture of Oxidized Polydimethylsiloxane and its Implications in Soft Lithography." In ASME 2011 International Mechanical Engineering Congress and Exposition. ASMEDC, 2011. http://dx.doi.org/10.1115/imece2011-64477.

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During the fabrication of nanopost arrays for measuring cellular forces, we have observed surface cracks in the negative molds used to replicate the arrays from a silicon master. These cracks become more numerous and severe with each replication such that repeated castings lead to arrays with missing or broken posts. This loss in pattern fidelity from the silicon master undermines the spatial resolution of the nanopost arrays in measuring cellular forces. We hypothesized that these cracks are formed because of a mismatch in the coefficient of thermal expansion (CTE) of PDMS and its oxidized surface layer. To study the fracture of PDMS due to thermal effects, we treated circular test samples of PDMS with oxidizing plasma and then heated them to cause surface cracks. These cracks were found to be more abundant at 180 °C than at lower temperatures. Finite element analysis of a bilayer material with a CTE mismatch was used to validate that thermal stresses are sufficient to overcome the fracture toughness of oxidized PDMS when heated to a curing temperature for PDMS. As a consequence, we have ascertained that elevated temperatures are a significant detriment to the reproducibility of nanoscale features in PDMS during replica molding.
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Yang, Bozhi, and Qiao Lin. "Planar Microfabricated Check Valves Utilizing Large Compliance of PDMS." In ASME 2005 International Mechanical Engineering Congress and Exposition. ASMEDC, 2005. http://dx.doi.org/10.1115/imece2005-81958.

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This paper presents three types of planar check valves that uniquely exploit the large compliance of simple PDMS structures. The micro check valves consist of a thin compliant flap and a rigid stopper embedded in a microchannel. The flap is perpendicular to the flow and lies near the stopper, forming a restricted fluid path inside the channel. In particular, a novel “zero flap-stopper gap” valve design was proposed and fabricated using a special technique, in which the flap and stopper are in contact naturally forming a normally-closed device with high diodicity. Testing results show that the check valves can achieve a diodicity up to 105. The check valves can be fabricated using the standard replica molding technique from PDMS, and thus are highly amenable to integration with other PDMS-based microfluidic systems.
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Gonzalez-Domenzain, Walter, and Ashwin A. Seshia. "Rapid Prototyping of PDMS Devices With Applications to Protein Crystallization." In ASME 2007 5th International Conference on Nanochannels, Microchannels, and Minichannels. ASMEDC, 2007. http://dx.doi.org/10.1115/icnmm2007-30046.

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This paper describes a microfabrication process for constructing three-dimensional microfluidic structures in polydimethylsiloxane (PDMS). Rapid prototyping of microfluidic devices is possible starting from ink-jet printed masks and by utilising replica molding to create fluidic structures in PDMS from SU-8 and SPR-220 masters pre-patterned on a silicon or glass substrate. Multi-layer bonded and stacked alignment of up to 13 different functional polymer microfluidic layers with through-layer fluidic interconnects has been demonstrated. Pneumatically actuated valves have also been demonstrated for the regulation of sub-10 nL of fluid volumes. The geometric design of the valves is described with experimental verification conducted on rounded and vertical channel profiles to examine the effects of channel geometry on valve leak rates. The PDMS-based technology allows for the fabrication of devices with extremely small reaction volumes and parallel sample processing, making these devices ideally suited to applications which require high throughput processing and the ability to conduct parallel assays with very limited volumes of reagent and sample. We describe the applications of this technology to protein crystallization in particular.
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Ishraq Bari, Saif Mohammad, Louis G. Reis, Thomas Holland, and Gergana G. Nestorova. "Numerical Analysis of Optimal Design Parameters for a Cell Co-Culture Microfluidic Platform With an Integrated Pressure-Controlled Valve." In ASME 2020 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2020. http://dx.doi.org/10.1115/imece2020-23957.

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Abstract This study reports the design, fabrication, and a two-dimensional numerical analysis to identify the optimal operating parameters of a novel microfluidic co-culture platform with an integrated pressure-controlled valve. Replica molding using 3D printed PDMS molds were used for the fabrication of the individual components of the device. Alternation of the position of the PDMS hydraulic valve permits individual manipulation of the cellular microenvironment of the two adjacent cell culture chambers (27.5 mm × 35 mm × 10 mm). The mathematical model analyzes the deflection profile of the valve in the vertical direction as a function of several parameters: valve thicknesses, the pressure exerted by the fluid inside the pressure chamber, and PDMS elasticity determined by the ratio of the elastomer base and the curing reagent. The valve understudy requires a deflection of 0.5 mm to completely isolate the two cell chambers. The combination of the optimal design parameters is identified using numerical analysis. Mathematical simulations show that the deflection of the membrane is inversely proportional to the valve membrane thickness and directly proportional to the pressure exerted by the fluid on the valve.
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Fomo Fondjo, Fabrice, and Jong-Hoon Kim. "Hybrid Nanocomposite Membrane for Wearable Bioelectronics." In ASME 2017 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2017. http://dx.doi.org/10.1115/imece2017-72339.

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There are strong needs for flexible and stretchable devices for the seamless integration with soft and curvilinear human skin or irregular textured cloths. However, the mechanical mismatch between the conventional rigid electronics and the soft human body results in many issues including contact breakage, or skin irritation. Due to the mechanical and electrical versatility of nanoscale forms, various nanomaterials have rapidly established themselves as promising electronic materials, replacing rigid wafer-based electronics in next-generation wearable devices. Here, we introduce a flexible, wearable bioelectronic system using an elastomeric hybrid nanocomposite, composed of zero-dimensional Carbon Black (CB) and one-dimensional Carbon Nanotubes (CNTs) and silver nanowires (AgNWs) in a polydimethylsiloxane (PDMS) matrix. Those materials were chosen due to their good electrical properties and their different length scale providing a continuous connection in the flexible PDMS matrix. To achieve a homogeneous dispersion, these nanomaterials were mechanically mixed in PDMS under shear flow using an overhead mixer. A hybrid nanocomposite membrane with dimensions of 15 mm diameter was then prepared by replica molding process. The electrical properties of the nanocomposite were measured over 5, 10 and 15hrs mixing time to investigate the point of electrical stability of the electrode and the electrical performance during EMG signal measurement. This soft nanocomposite, laminated on the skin, enables highly sensitive recording of electromyograms.
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Yang, Sung, and Jeffrey D. Zahn. "Particle Separation in Microfluidic Channels Using Flow Rate Control." In ASME 2004 International Mechanical Engineering Congress and Exposition. ASMEDC, 2004. http://dx.doi.org/10.1115/imece2004-60862.

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Microfluidic devices for particle recovery are successfully developed by controlling flow rate ratios of two daughter channels. Devices are prepared by using conventional Polydimethylsiloxane (PDMS) replica molding technique. The flow rate ratios of two daughter channels are controlled by changing the flow resistance through changing the geometry of the downstream channels. The particle recovery studies are conducted using 16 μm-diameter green fluorescent particles and using 8–10 μm-diameter human C8161 melanoma cells. For the fluorescent particles, the particle recovery efficiencies are 87.2%, 95.7%, 100%, and 100% for 2.5:1, 4:1, 6:1, and 8:1 flow rate ratios, respectively. Also, for the human C8161 melanoma cells, the cell recovery efficiencies are 88.7%, 98.9%, 100%, and 100% for 2.5:1, 4:1, 6:1, and 8:1 flow rate ratios, respectively.
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