Journal articles on the topic 'PDE'
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Bloom, Timothy J. "Cyclic nucleotide phosphodiesterase isozymes expressed in mouse skeletal muscle." Canadian Journal of Physiology and Pharmacology 80, no. 12 (December 1, 2002): 1132–35. http://dx.doi.org/10.1139/y02-149.
Full textDAY, Jonathan P., Julian A. T. DOW, Miles D. HOUSLAY, and Shireen-A. DAVIES. "Cyclic nucleotide phosphodiesterases in Drosophila melanogaster." Biochemical Journal 388, no. 1 (May 10, 2005): 333–42. http://dx.doi.org/10.1042/bj20050057.
Full textWright, Lyndon C., Joachim Seybold, Annette Robichaud, Ian M. Adcock, and Peter J. Barnes. "Phosphodiesterase expression in human epithelial cells." American Journal of Physiology-Lung Cellular and Molecular Physiology 275, no. 4 (October 1, 1998): L694—L700. http://dx.doi.org/10.1152/ajplung.1998.275.4.l694.
Full textSasseville, M., F. K. Albuz, F. J. Richard, and R. B. Gilchrist. "254. Evidences for a novel cAMP-phosphodiesterase expressed in the bovine ovarian follicle." Reproduction, Fertility and Development 20, no. 9 (2008): 54. http://dx.doi.org/10.1071/srb08abs254.
Full textNeumann, Joachim, Rafaela Voss, Ulrich Laufs, Christian Werner, and Ulrich Gergs. "Phosphodiesterases 2, 3 and 4 can decrease cardiac effects of H2-histamine-receptor activation in isolated atria of transgenic mice." Naunyn-Schmiedeberg's Archives of Pharmacology 394, no. 6 (February 12, 2021): 1215–29. http://dx.doi.org/10.1007/s00210-021-02052-y.
Full textTarpey, Siobhán B., Darrell R. Sawmiller, Claire Kelly, W. Joseph Thompson, and Mary I. Townsley. "Phosphodiesterase 3 activity is reduced in dog lung following pacing-induced heart failure." American Journal of Physiology-Lung Cellular and Molecular Physiology 284, no. 5 (May 1, 2003): L766—L773. http://dx.doi.org/10.1152/ajplung.00373.2002.
Full textPhillips, Peter G., Lu Long, Martin R. Wilkins, and Nicholas W. Morrell. "cAMP phosphodiesterase inhibitors potentiate effects of prostacyclin analogs in hypoxic pulmonary vascular remodeling." American Journal of Physiology-Lung Cellular and Molecular Physiology 288, no. 1 (January 2005): L103—L115. http://dx.doi.org/10.1152/ajplung.00095.2004.
Full textERDOGAN, Suat, and Miles D. HOUSLAY. "Challenge of human Jurkat T-cells with the adenylate cyclase activator forskolin elicits major changes in cAMP phosphodiesterase (PDE) expression by up-regulating PDE3 and inducing PDE4D1 and PDE4D2 splice variants as well as down-regulating a novel PDE4A splice variant." Biochemical Journal 321, no. 1 (January 1, 1997): 165–75. http://dx.doi.org/10.1042/bj3210165.
Full textSzczypka, Marianna. "Role of Phosphodiesterase 7 (PDE7) in T Cell Activity. Effects of Selective PDE7 Inhibitors and Dual PDE4/7 Inhibitors on T Cell Functions." International Journal of Molecular Sciences 21, no. 17 (August 25, 2020): 6118. http://dx.doi.org/10.3390/ijms21176118.
Full textTeng, Bunyan, Daniel N. Darlington, and Andrew P. Cap. "Adenosine Regulation of cAMP through Phosphodiesterases." Blood 132, Supplement 1 (November 29, 2018): 2424. http://dx.doi.org/10.1182/blood-2018-99-114929.
Full textGranovski, Olexiy, and Olena Boiarchuk. "FUNCTIONAL AND MUTATIONAL ANALYSIS OF THE IDENTIFICATION OF Pγ-BINDING RESIDUES ON PDE6α'." Grail of Science, no. 28 (June 22, 2023): 157–61. http://dx.doi.org/10.36074/grail-of-science.09.06.2023.23.
Full textSeybold, Joachim, Dirk Thomas, Martin Witzenrath, Şengül Boral, Andreas C. Hocke, Alexander Bürger, Armin Hatzelmann, et al. "Tumor necrosis factor-α–dependent expression of phosphodiesterase 2: role in endothelial hyperpermeability." Blood 105, no. 9 (May 1, 2005): 3569–76. http://dx.doi.org/10.1182/blood-2004-07-2729.
Full textManns, J. M., K. J. Brennan, S. B. Sheth, and R. W. Colman. "Differential Regulation of Human Platelet Responses by cGMP Inhibited and Stimulated cAMP Phosphodiesterases." Thrombosis and Haemostasis 87, no. 05 (2002): 873–79. http://dx.doi.org/10.1055/s-0037-1613099.
Full textGermain, Nöella, Elisabeth Boichot, Jean-Michel Planquois, and Vincent Lagente. "Reduced Airway Hyperresponsiveness by Phosphodiesterase 3 and 4 Inhibitors in Guinea-Pigs." Mediators of Inflammation 8, no. 3 (1999): 153–57. http://dx.doi.org/10.1080/09629359990487.
Full textŚwierczek, Artur, Krzysztof Pociecha, Hanna Plutecka, Marietta Ślusarczyk, Grażyna Chłoń-Rzepa, and Elżbieta Wyska. "Pharmacokinetic/Pharmacodynamic Evaluation of a New Purine-2,6-Dione Derivative in Rodents with Experimental Autoimmune Diseases." Pharmaceutics 14, no. 5 (May 19, 2022): 1090. http://dx.doi.org/10.3390/pharmaceutics14051090.
Full textSarfati, Marika, Véronique Mateo, Sylvie Baudet, Manuel Rubio, Christine Fernandez, Fréderic Davi, Jacques-Louis Binet, Jozo Delic, and Hélène Merle-Béral. "Sildenafil and vardenafil, types 5 and 6 phosphodiesterase inhibitors, induce caspase-dependent apoptosis of B-chronic lymphocytic leukemia cells." Blood 101, no. 1 (January 1, 2003): 265–69. http://dx.doi.org/10.1182/blood-2002-01-0075.
Full textReid, Ian A. "Role of Phosphodiesterase Isoenzymes in the Control of Renin Secretion: Effects of Selective Enzyme Inhibitors." Current Pharmaceutical Design 5, no. 9 (January 1999): 725–35. http://dx.doi.org/10.2174/1381612805666230111201536.
Full textAbusnina, Abdurazzag, Thérèse Keravis, Qingwei Zhou, Hélène Justiniano, Annelise Lobstein, and Claire Lugnier. "Tumour growth inhibition and anti-angiogenic effects using curcumin correspond to combined PDE2 and PDE4 inhibition." Thrombosis and Haemostasis 113, no. 02 (March 2015): 319–28. http://dx.doi.org/10.1160/th14-05-0454.
Full textLee, Dong I., and David A. Kass. "Phosphodiesterases and Cyclic GMP Regulation in Heart Muscle." Physiology 27, no. 4 (August 2012): 248–58. http://dx.doi.org/10.1152/physiol.00011.2012.
Full textFavot, Laure, Thérèse Keravis, Vincent Holl, Alain Bec, and Claire Lugnier. "VEGF-induced HUVEC migration and proliferation are decreased by PDE2 and PDE4 inhibitors." Thrombosis and Haemostasis 90, no. 08 (2003): 334–43. http://dx.doi.org/10.1160/th03-02-0084.
Full textMokra, Daniela, and Juraj Mokry. "Phosphodiesterase Inhibitors in Acute Lung Injury: What Are the Perspectives?" International Journal of Molecular Sciences 22, no. 4 (February 16, 2021): 1929. http://dx.doi.org/10.3390/ijms22041929.
Full textCheng, Jingfei, Michael A. Thompson, Henry J. Walker, Catherine E. Gray, Gina M. Warner, Wei Zhou, and Joseph P. Grande. "Lixazinone Stimulates Mitogenesis of Madin-Darby Canine Kidney Cells." Experimental Biology and Medicine 231, no. 3 (March 2006): 288–95. http://dx.doi.org/10.1177/153537020623100308.
Full textOgawa, Ryosuke, Michael B. Streiff, Artem Bugayenko, and Gregory J. Kato. "Inhibition of PDE4 phosphodiesterase activity induces growth suppression, apoptosis, glucocorticoid sensitivity, p53, and p21WAF1/CIP1 proteins in human acute lymphoblastic leukemia cells." Blood 99, no. 9 (May 1, 2002): 3390–97. http://dx.doi.org/10.1182/blood.v99.9.3390.
Full textCote, R. H. "Characteristics of Photoreceptor PDE (PDE6): similarities and differences to PDE5." International Journal of Impotence Research 16, S1 (June 2004): S28—S33. http://dx.doi.org/10.1038/sj.ijir.3901212.
Full textBloom, Timothy J. "Age-related alterations in cyclic nucleotide phosphodiesterase activity in dystrophic mouse leg muscle." Canadian Journal of Physiology and Pharmacology 83, no. 11 (November 1, 2005): 1055–60. http://dx.doi.org/10.1139/y05-085.
Full textSpence, S., G. Rena, G. Sweeney, and M. D. Houslay. "Induction of Ca2+/calmodulin-stimulated cyclic AMP phosphodiesterase (PDE1) activity in Chinese hamster ovary cells (CHO) by phorbol 12-myristate 13-acetate and by the selective overexpression of protein kinase C isoforms." Biochemical Journal 310, no. 3 (September 15, 1995): 975–82. http://dx.doi.org/10.1042/bj3100975.
Full textWang, Ya-Juan, Shun-De Song, Jun-Chun Chen, Xue-Feng Wang, Ya-Li Jiang, Qiang-Min Xie, Ji-Qiang Chen, Zi-Gang Li, and Hui-Fang Tang. "Effects of InactivatedBordetella pertussison Phosphodiesterase in the Lung of Ovalbumin Sensitized and Challenged Rats." Pulmonary Medicine 2014 (2014): 1–11. http://dx.doi.org/10.1155/2014/581738.
Full textMussen, Femke, Jana Van Broeckhoven, Niels Hellings, Melissa Schepers, and Tim Vanmierlo. "Unleashing Spinal Cord Repair: The Role of cAMP-Specific PDE Inhibition in Attenuating Neuroinflammation and Boosting Regeneration after Traumatic Spinal Cord Injury." International Journal of Molecular Sciences 24, no. 9 (May 2, 2023): 8135. http://dx.doi.org/10.3390/ijms24098135.
Full textHovmöller, Sven, Linus Hovmöller Zou, Xiaodong Zou, and Benjamin Grushko. "Structures of pseudo-decagonal approximants in Al−Co−Ni." Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences 370, no. 1969 (June 28, 2012): 2949–59. http://dx.doi.org/10.1098/rsta.2011.0310.
Full textIvey, F. Douglas, Lili Wang, Didem Demirbas, Christina Allain, and Charles S. Hoffman. "Development of a Fission Yeast-Based High-Throughput Screen to Identify Chemical Regulators of cAMP Phosphodiesterases." Journal of Biomolecular Screening 13, no. 1 (November 26, 2007): 62–71. http://dx.doi.org/10.1177/1087057107312127.
Full textTulsian, Nikhil K., Valerie Jia-En Sin, Hwee-Ling Koh, and Ganesh S. Anand. "Development of Phosphodiesterase–Protein-Kinase Complexes as Novel Targets for Discovery of Inhibitors with Enhanced Specificity." International Journal of Molecular Sciences 22, no. 10 (May 15, 2021): 5242. http://dx.doi.org/10.3390/ijms22105242.
Full textRickles, Richard J., Laura Pierce, Thomas Giordano, Winnie F. Tam, Douglas W. McMillin, Kenneth C. Anderson, Constantine Mitsiades, and Margaret S. Lee. "Adenosine A2A Receptor Agonism and PDE Inhibition: A Synergistic Multi-Target Mechanism Discovered through Systematic Combination Screening in Multiple Myeloma." Blood 112, no. 11 (November 16, 2008): 847. http://dx.doi.org/10.1182/blood.v112.11.847.847.
Full textFoureau, Anna V. Ivanina, David M. Foureau, Carol J. Farhangfar, and Kathryn F. Mileham. "Abstract 281: Phosphodiesterase 8/9 inhibition to sensitize squamous non-small cell lung cancer (NSCLC) to pemetrexed (PMX): A double-edge strategy." Cancer Research 83, no. 7_Supplement (April 4, 2023): 281. http://dx.doi.org/10.1158/1538-7445.am2023-281.
Full textZheng, Yang, Susanne Schroeder, Georgi K. Kanev, Sanaa S. Botros, Samia William, Abdel-Nasser A. Sabra, Louis Maes, et al. "To Target or Not to Target Schistosoma mansoni Cyclic Nucleotide Phosphodiesterase 4A?" International Journal of Molecular Sciences 24, no. 7 (April 6, 2023): 6817. http://dx.doi.org/10.3390/ijms24076817.
Full textNikawa, J., P. Sass, and M. Wigler. "Cloning and characterization of the low-affinity cyclic AMP phosphodiesterase gene of Saccharomyces cerevisiae." Molecular and Cellular Biology 7, no. 10 (October 1987): 3629–36. http://dx.doi.org/10.1128/mcb.7.10.3629-3636.1987.
Full textNikawa, J., P. Sass, and M. Wigler. "Cloning and characterization of the low-affinity cyclic AMP phosphodiesterase gene of Saccharomyces cerevisiae." Molecular and Cellular Biology 7, no. 10 (October 1987): 3629–36. http://dx.doi.org/10.1128/mcb.7.10.3629.
Full textXin, Wenkuan, Wei P. Feinstein, Andrea L. Britain, Cristhiaan D. Ochoa, Bing Zhu, Wito Richter, Silas J. Leavesley, and Thomas C. Rich. "Estimating the magnitude of near-membrane PDE4 activity in living cells." American Journal of Physiology-Cell Physiology 309, no. 6 (September 15, 2015): C415—C424. http://dx.doi.org/10.1152/ajpcell.00090.2015.
Full textKopanitsa, Liliya, Maksym V. Kopanitsa, Dewi Safitri, Graham Ladds, and David S. Bailey. "Suppression of Proliferation of Human Glioblastoma Cells by Combined Phosphodiesterase and Multidrug Resistance-Associated Protein 1 Inhibition." International Journal of Molecular Sciences 22, no. 18 (September 7, 2021): 9665. http://dx.doi.org/10.3390/ijms22189665.
Full textDay, Jonathan P., Miles D. Houslay, and Shireen-A. Davies. "A novel role for a Drosophila homologue of cGMP-specific phosphodiesterase in the active transport of cGMP." Biochemical Journal 393, no. 2 (December 23, 2005): 481–88. http://dx.doi.org/10.1042/bj20051505.
Full textMeima, Marcel E., Ricardo M. Biondi, and Pauline Schaap. "Identification of a Novel Type of cGMP Phosphodiesterase That Is Defective in the ChemotacticstmFMutants." Molecular Biology of the Cell 13, no. 11 (November 2002): 3870–77. http://dx.doi.org/10.1091/mbc.e02-05-0285.
Full textHanson, Kimberly A., James W. Ziegler, Sergei D. Rybalkin, Jim W. Miller, Steven H. Abman, and William R. Clarke. "Chronic pulmonary hypertension increases fetal lung cGMP phosphodiesterase activity." American Journal of Physiology-Lung Cellular and Molecular Physiology 275, no. 5 (November 1, 1998): L931—L941. http://dx.doi.org/10.1152/ajplung.1998.275.5.l931.
Full textMurray, Fiona, Hemal H. Patel, Ryan Y. S. Suda, Shen Zhang, Patricia A. Thistlethwaite, Jason X. J. Yuan, and Paul A. Insel. "Expression and activity of cAMP phosphodiesterase isoforms in pulmonary artery smooth muscle cells from patients with pulmonary hypertension: role for PDE1." American Journal of Physiology-Lung Cellular and Molecular Physiology 292, no. 1 (January 2007): L294—L303. http://dx.doi.org/10.1152/ajplung.00190.2006.
Full textBlanco-Rivero, Javier, and Fabiano E. Xavier. "Therapeutic Potential of Phosphodiesterase Inhibitors for Endothelial Dysfunction- Related Diseases." Current Pharmaceutical Design 26, no. 30 (September 4, 2020): 3633–51. http://dx.doi.org/10.2174/1381612826666200403172736.
Full textShen, Kunyu, David W. Johnson, and Glenda C. Gobe. "The role of cGMP and its signaling pathways in kidney disease." American Journal of Physiology-Renal Physiology 311, no. 4 (October 1, 2016): F671—F681. http://dx.doi.org/10.1152/ajprenal.00042.2016.
Full textOkatan, Esma N., and Belma Turan. "The contribution of phosphodiesterases to cardiac dysfunction in rats with metabolic syndrome induced by a high-carbohydrate diet." Canadian Journal of Physiology and Pharmacology 97, no. 11 (November 2019): 1064–72. http://dx.doi.org/10.1139/cjpp-2019-0006.
Full textWang, Huanchen, Stefan Kunz, Gong Chen, Thomas Seebeck, Yiqian Wan, Howard Robinson, Sibylla Martinelli, and Hengming Ke. "Biological and Structural Characterization of Trypanosoma cruzi Phosphodiesterase C and Implications for Design of Parasite Selective Inhibitors." Journal of Biological Chemistry 287, no. 15 (February 21, 2012): 11788–97. http://dx.doi.org/10.1074/jbc.m111.326777.
Full textMaronde, Erik. "Influence of Phosphodiesterase Inhibition on CRE- and EGR1-Dependent Transcription in a Mouse Hippocampal Cell Line." International Journal of Molecular Sciences 21, no. 22 (November 17, 2020): 8658. http://dx.doi.org/10.3390/ijms21228658.
Full textSu, Yi-Hsien, and Victor D. Vacquier. "Cyclic GMP-specific Phosphodiesterase-5 Regulates Motility of Sea Urchin Spermatozoa." Molecular Biology of the Cell 17, no. 1 (January 2006): 114–21. http://dx.doi.org/10.1091/mbc.e05-08-0820.
Full textMendoza, G. A., and F. Treves. "linear PDE." Duke Mathematical Journal 63, no. 2 (July 1991): 355–77. http://dx.doi.org/10.1215/s0012-7094-91-06315-5.
Full textOliveira, Tiago Roux, and Miroslav Krstic. "Extremum seeking boundary control for PDE–PDE cascades." Systems & Control Letters 155 (September 2021): 105004. http://dx.doi.org/10.1016/j.sysconle.2021.105004.
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