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1

Moore, Rick A. "Measuring the Impact of Recognized Patient-Centered Medical Homes (PCMH)." Thesis, Virginia Commonwealth University, 2016. http://pqdtopen.proquest.com/#viewpdf?dispub=3746418.

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It has been estimated that by 2020 nearly one-third of all Americans (almost 160 million people) will have at least one chronic disease to manage and the cost of health care will consume over 20 percent of the GDP. The Obama Administration responded to this pending crisis by passing the Patient Protection and Affordable Care Act (PPACA) in 2010. This major legislation aims to instill patient-centered, accountable care into the health care delivery system. Specifically, the United States government is on a mission to reduce the utilization of expensive inpatient care, while increasing access to primary care for all Americans, thereby lowering the total cost of health care.

Primary care practices organized around the principles of the patient-centered medical home (PCMH) can better manage their patients, especially their patients with chronic conditions; and become accountable for their care. In 2008, the National Committee for Quality Assurance (NCQA) released practice-level recognition standards based on the seven Joint Principles of the PCMH, to aid doctors seeking to transform their practices into effective patient-centered delivery systems.

The results of several published studies have touted the successes (e.g., reduced emergency department visits, reduced hospitalizations) of the PCMH model at individual practice sites. These localized successes demonstrated that the principle tenets of the PCMH model—care coordination, team-based care, population management—helped lower utilization of more expensive health care services within the specific practice settings evaluated. However, there has been no study to determine if these core tenets are having a broader impact on the health care delivery system within a community.

One hypothesized outcome of a health care system centered on the PCMH care model is better care coordination and more effective, whole-person care management across the continuum of health care; resulting in a more efficient system that can prevent avoidable hospitalizations.

This dissertation proposal seeks to understand if the increasing numbers (density) of recognized PCMH practices in communities affect avoidable hospitalizations related to ambulatory care sensitive conditions (ACSC), as measured by the AHRQ Composite Prevention Quality Indicators (PQI). The research has two purposes:

1. Establish constructs and hypotheses to measure the effect of the increasing numbers of NCQA-Recognized PCMH practices in communities (counties).

2. Using an outcomes-based measurement approach, investigate the relationship between growing densities of NCQA-Recognized PCMH practice doctors among all primary care doctors (PCD) in a community and the associated impact on the utilization of inpatient care, specifically related to ACSCs, as measured by the AHRQ Composite PQIs.

The research is quasi-experimental in design and is based on a retrospective (2008–2011) analysis of existing data from the NCQA PCMH program, the AHRQ Composite PQI and the Centers for Medicare & Medicaid Services (CMS) National Provider Identification (NPI) databases. Analysis will link NCQA-Recognized PCMH practices (independent variable), AHRQ Risk Adjusted Composite PQIs (dependent variable), and the CMS NPI (total PCDs) on Federal Information Processing Standard (FIPS) identifiers across 114 state and county-level geographical areas in Vermont and North Carolina. The research will inform the following hypotheses:

1. Does the research literature support the measurement construct proposed in this study?

2. Communities with concentrations of recognized PCMH practices among primary care practices will have lower risk-adjusted avoidable hospital admission rates.

3. The use of technology and care coordination will have a greater predictive correlation on risk-adjusted avoidable hospital admission rates than other PCMH capabilities.

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2

Moore, Rick. "Measuring the Impact of Recognized Patient-Centered Medical Homes (PCMH)." VCU Scholars Compass, 2015. http://scholarscompass.vcu.edu/etd/4069.

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This dissertation proposal seeks to understand if the increasingnumbers (density) of recognized PCMH practices incommunities affect avoidable hospitalizations related toambulatory care sensitive conditions (ACSC), as measured bythe AHRQ Composite Prevention Quality Indicators (PQI). Theresearch has two purposes: 1. Establish constructs and hypotheses to measurethe effect of the increasing numbers of NCQA-Recognized PCMH practices in communities(counties). 2. Using an outcomes-based measurement approach,investigate the relationship between growingdensities of NCQA-Recognized PCMH practicedoctors among all primary care doctors (PCD) ina community and the associated impact on theutilization of inpatient care, specifically related toACSCs, as measured by the AHRQ CompositePQIs. The research is quasi-experimental in design and is based on aretrospective (2008–2011) analysis of existing data from theNCQA PCMH program, the AHRQ Composite PQI and theCenters for Medicare & Medicaid Services (CMS) NationalProvider Identification (NPI) databases. Analysis will linkNCQA-Recognized PCMH practices (independent variable),AHRQ Risk Adjusted Composite PQIs (dependent variable),and the CMS NPI (total PCDs) on Federal InformationProcessing Standard (FIPS) identifiers across 114 state andcounty-level geographical areas in Vermont and North Carolina.
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3

Shinde, Nikhil Vijay. "A Study on the Impact of Patient Centered Medical Home (PCMH) Implementation on Nursing Work Practice." Thesis, North Dakota State University, 2012. https://hdl.handle.net/10365/26660.

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Primary care and nursing are important components of the U.S. healthcare system and are facing challenges of quality, access, cost, time spent and inefficiencies of clinical activities. Patient Centered Medical Home (PCMH) is a newly developed care model which has the potential to overcome these challenges. The present study uses a questionnaire approach to find the impact PCMH implementation may have on nursing practice and subsequently primary care. Analysis of the data collected from the questionnaire revealed some surprising results about the nursing practice. For example nurses spend less time on direct care and more time on indirect care and documentation. The nursing demand in terms of Full Time Equivalent (FTE) for nurses decreases. The future demand for nurses (not in FTE) shows an increase after PCMH implementation. The satisfaction level and overall health of patients, patient readmission, job satisfaction of nurses and department productivity shows improvement after PCMH implementation.
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4

Culcuoglu, Mustafa U. "Reengineering Community Based Chronic Care Delivery Systems: Theory and Applications." University of Akron / OhioLINK, 2021. http://rave.ohiolink.edu/etdc/view?acc_num=akron1627573050496332.

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5

Wegman, Kevin R. "Numerical Modeling of a Printed Circuit Heat Exchanger Based on Experimental Results from the High-Temperature Helium Test Facility." The Ohio State University, 2016. http://rave.ohiolink.edu/etdc/view?acc_num=osu1461266010.

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6

Nix, Tanya J. "Evolution of Physician-Centric Business Models Under Patient Protection and Affordable Care Act." ScholarWorks, 2014. http://scholarworks.waldenu.edu/dissertations/123.

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For several decades, the cost of medical care in the United States has increased exponentially. Congress enacted the Patient Protection and Affordable Care Act (PPACA) of 2010 to ensure affordable healthcare to the citizens of the United States. The purpose of this case study was to explore physicians' perspectives regarding physician-centric business models evolving under the requirements of PPACA legislation. Complex adaptive systems formed the conceptual framework for this study. Data were gathered through face-to-face, semistructured interviews and e-mail questionnaires with a purposeful sample of 20 participants across 14 medical specialties within Northeast Texas. Participant perceptions were elicited regarding opinions of PPACA legislation and the viability of business models under the PPACA. In addition, a word cloud was used to identify 3 prevalent or universal themes that emerged from participant interviews and questionnaires, including (a) use of mid-level practitioners, (b) changes to provider practices, and (c) lack of business education. The implications for positive social change include the potential to develop innovative models for the delivery of medical care that will improve the health of the aggregate population. Healthcare leaders may use the findings to advance the evolution of physician business models that meet the needs of healthcare stakeholders. These findings may also inform healthcare leaders of the need to develop cost-effective and innovative organizational models that are distinct to individual patient populations.
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7

Mylavarapu, Sai K. "Development of Compact Heat Exchangers for Very High-Temperature Gas-Cooled Reactors." The Ohio State University, 2008. http://rave.ohiolink.edu/etdc/view?acc_num=osu1228150070.

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8

Mylavarapu, Sai Kiran. "Design, Fabrication, Performance Testing, and Modeling of Diffusion Bonded Compact Heat Exchangers in a High-Temperature Helium Test Facility." The Ohio State University, 2011. http://rave.ohiolink.edu/etdc/view?acc_num=osu1321996306.

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9

Watkins, Sydney L. "Patient-Centered Medical Homes and Parental Attention-Deficit Hyperactivity Disorder Medication Beliefs and Adherence." ScholarWorks, 2018. https://scholarworks.waldenu.edu/dissertations/5044.

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As many as 87% of children discontinue ADHD medication, which can lead to clinically significant academic, cognitive, and social impairment. ADHD costs billions of dollars to the healthcare and educational systems, and previous attempts to stem these costs and increase ADHD medication adherence have been unsuccessful. The purpose of this study was to determine if patient-centered medical homes (PCMH), which have been shown to improve patient health outcomes, impact parental beliefs (benefits vs. risks) about ADHD medication and adherence to ADHD medication. The theory of planned behavior was the theoretical framework for this study. There were 294 parents of children between the ages of 5 and 12 who had been prescribed ADHD medication who participated in a quantitative self-administered survey. Parental beliefs were assessed using the Beliefs About Medicines Questionnaire-Specific, and medication adherence was assessed using the Morisky Medication Adherence Scale-8. The 2007 National Survey of Children's Health was used to determine group assignment. A MANCOVA was used to analyze the data and found parents in the PCMH group scored significantly higher in their beliefs that the benefits outweighed the risks of ADHD medication. However, no significant differences were found between groups related to parental adherence to ADHD medication. More research is recommended to learn how PCMHs can change positive ADHD medication beliefs into better ADHD medication adherence. This study has social change implications as it increases what is known about PCMHs and how they impact health outcomes. It also supports previous literature in the need to deliver all PCMH services, which is required to realize the full benefit of PCMHs.
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10

Figley, Justin T. "Numerical Modeling and Performance Analysis of Printed Circuit Heat Exchanger for Very High-Temperature Reactors." The Ohio State University, 2009. http://rave.ohiolink.edu/etdc/view?acc_num=osu1244036854.

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11

Tanenbaum, Joseph Elias. "The Association of Health Care Delivery and Payment Innovations with Avoidable Hospitalizations." Case Western Reserve University School of Graduate Studies / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=case1530814492308274.

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12

Chen, Minghui. "DESIGN, FABRICATION, TESTING, AND MODELING OF A HIGH-TEMPERATURE PRINTED CIRCUIT HEAT EXCHANGER." The Ohio State University, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=osu1431072434.

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13

RANA, SACHIN. "CFD SIMULATION OF SHELL AND TUBE HEAT EXCHANGER FILLED WITH PHASE CHANGE MATERIAL FOR SOLAR WATER HEATING SYSTEM." Thesis, 2023. http://dspace.dtu.ac.in:8080/jspui/handle/repository/20147.

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Solar energy, the most promising source of energy, requires thermal energy storage (TES) due to its intermittent nature. Storage of thermal energy can take the form of sensible heat storage (SHS), latent heat storage (LHS), and thermo-chemical storage (TCS). The amount of energy that is stored in SHS depends on the specific heat of the substance, the change in temperature, and the mass of the storage material since heat energy is retained by raising the temperature of the storage material without going through a phase transition. However, LHS involves a phase transition, when heated to the constant temperature, between solid-liquid, solid-solid, and liquid gas states and vice versa. Solid-solid phase transitions require a lower energy storage capacity than liquid-gas phase transitions which require a large increase in volume. As a result, the solid liquid transformation is most commonly used in LHS applications because it is more efficient than other transformations. In this study, the methods of enhancing the heat transmission in a latent heat thermal energy storage (LHTES) system with a heat exchanger of shell & tube type having a phase change material (PCM) in shell region, known as PCM heat exchanger (PCMHE), and carrying a number of tubes of circular, elliptical and square shape, to flow of a heat transfer fluid (HTF) using a two-dimension (2D) computational fluid dynamics (CFD) model has been presented. Enhancement of heat transfer in the LHTES system may be obtained either by using a suitable geometric configuration of PCMHE and/or by increasing the thermal conductivity of PCM. Heat transfer enhancements in LHTES systems can be achieved by using extended surfaces like fins and heat pipes. To enhance the heat transmission between tubes and PCM, a number of rectangular fins are attached to the outer surface of the circular, elliptical, and square tubes of the PCMHE. Geometrical modeling of PCMHE of shell and tube type, in which a solid Gallium as a PCM is filled in the outer shell and an HTF is flowing inside tubes, has been done in Solid Works. In this vi work, the outer shell of PCMHE is selected in two different shapes: square and circular. The tubes inside the outer shell of PCMHE are also selected in different shapes i.e. circular, square, and elliptical as well as in different configurations i.e. with and without fins. All the geometries of PCMHE modeled in Solid Works saves in IGES format and transported in the Ansys Fluent to convert them into finite element models by mesh generation of the geometries. Unstructured triangular elements are used for the mesh generation of all the geometries of PCMHE. After the mesh generation is completed, the meshed model is transferred to the Ansys Fluent setup and solution mode. In the setup mode of Ansys Fluent, further operations like solver type, time dependency, gravitational acceleration, material properties, boundary conditions, etc. are selected and then the solution is executed. 2D CFD numerical investigation of heat transfer & melting of PCM in different geometries of PCMHE has been performed. After the execution of the solution of all geometries of PCMHE has been completed, viewing and postprocessing of the results are performed. CFD investigations of heat exchanger geometries have been performed at different temperatures for liquid fraction and mean temperature of PCM as well as melting time and time for attainment of applied temperature. Results show that enhancement of heat transfer and reduction in melting time take place by employing a number of fins on tubes of PCMHE. It has also been concluded by comparing the different geometries of PCMHE that the configuration having the similar shape of shell and tubes (both shell and tubes are either square or circular) has the maximum heat transfer rate and lowest melting time compared to other geometries of PCMHE. Based on the available simulation data, the findings are validated and show good agreement, which suggests a deviation of 3.8 & 4.1 percent.
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14

Lahare, Pushpendra Bahadur Singh. "Analysis of Rectangular Channel Printed Circuit Heat Exchanger(PCHE)." Thesis, 2016. http://ethesis.nitrkl.ac.in/8225/1/2016_MT_214ME5330_Analysis_of_Rectangular.pdf.

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Cryogenic heat exchanger used for conversion of energy of one fluid to another as here Printed Circuit Heat Exchanger (PCHE) used as compact heat exchanger of very small hydraulic diameter as compared to its length, due to small hydraulic diameter of long length flow becomes completely developed with laminar in nature results higher in effectiveness and less axial conduction loss due to its design. Mass flow distribution and thermal analysis in four layer channels by using the design of inlet header location and distributor path for both hot and cold fluid in counter flow direction at different Reynolds number range (100
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15

Bernard, Alec Jordan. "Effects of Patient-Centered Medical Home model on primary care." Thesis, 2014. https://hdl.handle.net/2144/15354.

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The Patient-Centered Medical Home (PCMH) model has been touted as one of the most promising reform efforts of the largely inefficient U.S. healthcare system. In comparison to the current primary care system, the PCMH is a care delivery model that is based on the principles of care-coordination, enhanced access, and team-based collaboration as a means of providing comprehensive, patient-centered medical care. The current literature contains a limited number of review articles synthesizing the data of numerous PCMH outcome studies. Even a smaller number draws definitive conclusions as to whether PCMH is a viable model upon which to reform the US healthcare system. This literature review will examine the available results of PCMH studies in light of their ability to 1) decrease the overall cost of healthcare 2) increase the efficiency of the continuity of care and 3) to increase positive patient outcomes through proactive patient care. Additionally, these results will be examined in regard to their longevity as a viable model of reform and specifically as it compares to the current US healthcare system. This review will determine whether there is statistical evidence that the Patient-Centered Medical Home is a successful model to decrease healthcare costs, increase healthcare efficiency as well as increasing positive patient outcomes. In addition, this review hopes to point to ways in which the model could be improved in order to more completely achieve the goals listed above.
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16

Pezeshki, Abdul Mohammad. "Enforcing dendritic cell vaccines by manipulating the MHC II antigen presentation pathway." Thèse, 2012. http://hdl.handle.net/1866/9140.

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Les vaccins à base de cellules dendritiques (DCs) constituent une avenue très populaire en immunothérapie du cancer. Alors que ces cellules peuvent présenter des peptides exogènes ajoutés au milieu, l’efficacité de chargement de ces peptides au le complexe majeur d'histocompatibilité (CMH) de classe II est limitée. En effet, la majorité des molécules du CMH II à la surface des DCs sont très stable et l’échange de peptide spontané est minime. Confinée aux vésicules endosomales, HLA-DM (DM) retire les peptides des molécules du CMH II en plus de leur accorder une conformation réceptive au chargement de peptides. Il est possible, cependant, de muter le signal de rétention de DM de façon à ce que la protéine s’accumule en surface. Nous avons émis l’hypothèse que ce mutant de DM (DMY) sera aussi fonctionnel à la surface que dans la voie endosomale et qu’il favorisera le chargement de peptides exogènes aux DCs. Nous avons utilisé un vecteur adénoviral pour exprimer DMY dans des DCs et avons montrer que la molécule augmente le chargement de peptides. L’augmentation du chargement peptidique par DMY est autant qualitatif que quantitatif. DMY améliore la réponse T auxiliaire (Th) du coté Th1, ce qui favorise l’immunité anti-cancer. Du côté qualitatif, le chargement de peptides résulte en des complexes peptide-CMHII (pCMH) d’une conformation supérieure (conformère). Ce conformère (Type A) est le préféré pour la vaccination et DMY édite avec succès les complexes pCMH à la surface en éliminant ceux de type B, lesquels sont indésirables. La fonction de DM est régulée par HLA-DO (DO). Ce dernier inhibe l’habilité de DM à échanger le peptide CLIP (peptide dérivée de la chaîne invariante) en fonction du pH, donc dans les endosomes tardifs. Mes résultats indiquent que la surexpression de DO influence la présentation des superantigènes (SAgs) dépendants de la nature du peptide. Il est probable que DO améliore indirectement la liaison de ces SAgs au pCMH dû à l’accumulation de complexe CLIP-CMH, d’autant plus qu’il neutralise la polarisation Th2 normalement observée par CLIP. Ensemble, ces résultats indiquent que DMY est un outil intéressant pour renforcer le chargement de peptides exogènes sur les DCs et ainsi générer des vaccins efficaces. Un effet inattendu de DO sur la présentation de certains SAgs a aussi été observé. Davantage de recherche est nécessaire afin de résoudre comment DMY et DO influence la polarisation des lymphocytes T auxiliaires. Cela conduira à une meilleure compréhension de la présentation antigénique et de son étroite collaboration avec le système immunitaire.
Dendritic cell peptide-based vaccines are the most common immunotherapy approach in cancer therapy. While, in principle, dendritic cells (DCs) could be loaded efficiently by exogenously added tumor peptides, their loading efficacy is severely reduced due to low number of peptide-receptive MHC II on cell surface. Most surface MHC II molecules are either occupied by endogenous peptides or are inactive due to a conformation that is not receptive for free peptides. In MHC II antigen presentation pathway, HLA-DM (DM) in acidic endosomal vesicles removes the self-peptides and grants a peptide receptive conformation to MHC II. Mutating of an intracellular sorting motif in DM, renders its accumulation on cell surface. We hypothesized that the mutant DM (DMY) is functional on cell surface and can generate peptide receptive MHC II on surface of DCs for exogenous peptide loading. By using an adenoviral vector that expresses DMY, we found that DMY is functional on surface of DCs. DMY supplied peptide receptive MHC II on surface of DCs and improved exogenous peptide loading. The improvement of peptide loading by DMY is both quantitative and qualitative. DMY improves helper T cell (Th) response in Th1 direction that favors anti-cancer immunity. The qualitative improvement of peptide loading extends to loading of superior conformational isomer (conformer) of peptide-MHC complexes. This superior conformer (type A) is the favourite type for vaccination approaches and DMY successfully edits peptide-MHC conformers on cell surface level by eliminating undesirable one (type B). Function of DM is regulated by HLA-DO (DO) and it is well accepted that in acidic pH of late endosomes, DO inhibits function of DM by preventing removal of class II associated invariant chain peptide (CLIP) from peptide binding groove of MHC II. My results indicate that DO overexpression, changes binding of peptide-dependent superantigens to MHC II molecules. Superantigens (SAgs) are small microbial proteins that bind out side peptide binding groove of MHC II. DO probably enhances binding of peptide-dependent SAgs by forcing the accumulation of CLIP on the cell surface of antigen presenting cells. DO also neutralizes Th2 polarization by CLIP. Collectively, these results indicate that DMY is a valuable tool for improvement of exogenous peptide loading in DCs vaccines. An unnoticed effect of DO on SAgs binding was also recognized. Further investigations are needed to clarify the mechanisms by which, DMY and DO influence Th polarization. This would provide a better understanding of antigen presentation pathway and its interaction with immune system.
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