Journal articles on the topic 'PCI-34051'
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Balasubramanian, Sriram, Susanne Steggerda, Mint Sirisawad, Marshall Schreeder, Luke Doiron, and Joseph J. Buggy. "The Histone Deacetylase-8 (HDAC8) Selective Inhibitor PCI-34051 Decreases Interleukin-1 Beta Secretion in Vitro and Reduces Inflammation in Vivo." Blood 112, no. 11 (November 16, 2008): 2581. http://dx.doi.org/10.1182/blood.v112.11.2581.2581.
Full textKim, Ji Yoon, Seung Yoon Han, Jung Yoo, Go Woon Kim, Yu Hyun Jeon, Sang Wu Lee, Jongsun Park, and So Hee Kwon. "HDAC8-Selective Inhibition by PCI-34051 Enhances the Anticancer Effects of ACY-241 in Ovarian Cancer Cells." International Journal of Molecular Sciences 23, no. 15 (August 3, 2022): 8645. http://dx.doi.org/10.3390/ijms23158645.
Full textCheng, Alfred Sze, Yu Feng, Jingying Zhou, Weiqin Yang, Hangyong Sun, Zhiwei Chen, Tyler Goodwin, Rihe Liu, and Leaf Huang. "HDAC8 inhibition modulates liver tumor microenvironment: Rationale for combined epigenetic and immunotherapy." Journal of Immunology 198, no. 1_Supplement (May 1, 2017): 76.26. http://dx.doi.org/10.4049/jimmunol.198.supp.76.26.
Full textHendrix, Sven, Selien Sanchez, Elissia Ventriglia, and Stefanie Lemmens. "HDAC8 Inhibition Reduces Lesional Iba-1+ Cell Infiltration after Spinal Cord Injury without Effects on Functional Recovery." International Journal of Molecular Sciences 21, no. 12 (June 25, 2020): 4539. http://dx.doi.org/10.3390/ijms21124539.
Full textBalasubramanian, S., J. Ramos, W. Luo, M. Sirisawad, E. Verner, and J. J. Buggy. "A novel histone deacetylase 8 (HDAC8)-specific inhibitor PCI-34051 induces apoptosis in T-cell lymphomas." Leukemia 22, no. 5 (February 7, 2008): 1026–34. http://dx.doi.org/10.1038/leu.2008.9.
Full textRamos, Teresa L., Luis Ignacio Sánchez-Abarca, Rosón Beatriz, Concepción Rodríguez Serrano, Alba Redondo, Rebeca Ortega, Ángel Hernández-Hernández, et al. "HDAC8 Overexpression in Mesenchymal Stromal Cells from JAK2+ myeloproliferative Neoplasms: A New Therapeutic Target?" Blood 126, no. 23 (December 3, 2015): 2831. http://dx.doi.org/10.1182/blood.v126.23.2831.2831.
Full textBai, Shi-Yao, Meng-Lu Li, Yuan Ren, and Xin-Ming Su. "HDAC8-inhibitor PCI-34051-induced exosomes inhibit human bronchial smooth muscle cell proliferation via miR-381-3p mediated TGFB3." Pulmonary Pharmacology & Therapeutics 71 (December 2021): 102096. http://dx.doi.org/10.1016/j.pupt.2021.102096.
Full textHeppt, Markus V., Anja Wessely, Eva Hornig, Claudia Kammerbauer, Saskia A. Graf, Robert Besch, Lars E. French, et al. "HDAC2 Is Involved in the Regulation of BRN3A in Melanocytes and Melanoma." International Journal of Molecular Sciences 23, no. 2 (January 13, 2022): 849. http://dx.doi.org/10.3390/ijms23020849.
Full textQi, Jing, Sandeep Singh, Qi Cai, Hongjun Liu, Hieu Vu, Sriram Balasubramanian, and Ya-Huei Kuo. "CBFβ-SMMHC Inactivates p53 Tumor Suppressor Through Aberrant Protein Interaction and Recruitment of HDAC8." Blood 120, no. 21 (November 16, 2012): 772. http://dx.doi.org/10.1182/blood.v120.21.772.772.
Full textChyra, Zuzana, Maria Gkotzamanidou, Masood A. Shammas, Vassilis L. Souliotis, Yan Xu, Mehmet K. Samur, Aaron B. Beeler, Roman Hajek, Mariateresa Fulciniti, and Nikhil C. Munshi. "HDAC8 Maintain Cytoskeleton Integrity Via Homologous Recombination and Represent a Novel Therapeutic Target in Multiple Myeloma." Blood 134, Supplement_1 (November 13, 2019): 4385. http://dx.doi.org/10.1182/blood-2019-130700.
Full textGkotzamanidou, Maria, Masood Shammas, Jesus Martin Sanchez, Lai Ding, Stephane Minvielle, Florence Magrangeas, Herve Avet-Loiseau, Kenneth C. Anderson, and Nikhil C. Munshi. "HDAC8 Mediates Homologous Recombination and Cytoskeleton Integrity in Myeloma with Potential Impact on Cell Growth and Survival." Blood 124, no. 21 (December 6, 2014): 416. http://dx.doi.org/10.1182/blood.v124.21.416.416.
Full textKitadate, Akihiro, Sho Ikeda, Fumito Abe, Naoto Takahashi, Norio Shimizu, Kosei Matsue, and Hiroyuki Tagawa. "Histone Deacetylase Inhibitors Downregulate CCR4 Expression and Decrease Mogamulizumab Efficacy in CCR4-Positive Mature T-Cell Lymphomas." Blood 130, Suppl_1 (December 7, 2017): 720. http://dx.doi.org/10.1182/blood.v130.suppl_1.720.720.
Full textGoncalves, Kevin A., Megan D. Hoban, Jennifer L. Proctor, Hillary L. Adams, Sharon L. Hyzy, Anthony E. Boitano, and Michael P. Cooke. "Phenotype Does Not Always Equal Function: HDAC Inhibitors and UM171, but Not SR1, Lead to Rapid Upregulation of CD90 on Non-Engrafting CD34+CD90-Negative Human Cells." Blood 130, Suppl_1 (December 7, 2017): 659. http://dx.doi.org/10.1182/blood.v130.suppl_1.659.659.
Full textZhang, Pu, Lindsey Brinton, James S. Blachly, John C. Byrd, and Rosa Lapalombella. "Identification of Novel Synthetic Lethal Partners of NAMPT Inhibitor By CRISPR-Cas9 Screens in Acute Myeloid Leukemia." Blood 134, Supplement_1 (November 13, 2019): 2072. http://dx.doi.org/10.1182/blood-2019-129036.
Full textZhou, Xun, Hui Chen, Yingfeng Shi, Jinqing Li, Xiaoyan Ma, Lin Du, Yan Hu, et al. "Histone deacetylase 8 inhibition prevents the progression of peritoneal fibrosis by counteracting the epithelial-mesenchymal transition and blockade of M2 macrophage polarization." Frontiers in Immunology 14 (February 23, 2023). http://dx.doi.org/10.3389/fimmu.2023.1137332.
Full textKurzawa, Nils, Isabelle Becher, Sindhuja Sridharan, Holger Franken, André Mateus, Simon Anders, Marcus Bantscheff, Wolfgang Huber, and Mikhail M. Savitski. "A computational method for detection of ligand-binding proteins from dose range thermal proteome profiles." Nature Communications 11, no. 1 (November 13, 2020). http://dx.doi.org/10.1038/s41467-020-19529-8.
Full text"THERAPETIC EFFECTS OF HDAC8 SPECIFIC INHIBITOR PCI-34051 IN ACUTE ASTHMATIC MICE AND ITS EFFECT ON GALECTIN-3." Respirology 22 (November 2017): 89. http://dx.doi.org/10.1111/resp.13207_5.
Full textSchmidt, Oxana, Nadja Nehls, Carolin Prexler, Kristina von Heyking, Tanja Groll, Katharina Pardon, Heathcliff D. Garcia, et al. "Class I histone deacetylases (HDAC) critically contribute to Ewing sarcoma pathogenesis." Journal of Experimental & Clinical Cancer Research 40, no. 1 (October 15, 2021). http://dx.doi.org/10.1186/s13046-021-02125-z.
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