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Academic literature on the topic 'Pc-Minor'

Author: Grafiati

Published: 25 May 2024

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Journal articles on the topic "Pc-Minor"

Liu, S., J. K. Pinski, and S. A. Ingles. "Prostate cancer outcomes and polymorphism in LHRH and LH receptors and SHBG." Journal of Clinical Oncology 29, no. 7_suppl (March 1, 2011): 5. http://dx.doi.org/10.1200/jco.2011.29.7_suppl.5.

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5 Background: The hypothalamic-pituitary-gonadal axis is integral to androgen synthesis and the management of prostate cancer (PC). Genetic variation in the receptors of this pathway may impact the efficiency of signal transduction and overall clinical course. We examined polymorphisms in four receptors central to this pathway: luteinizing hormone-releasing hormone receptor (LHRHR), luteinizing hormone receptor (LHR), androgen receptor (AR) and steroid hormone binding globulin (SHBG). We examined the association between these genotypes and survival. Methods: Patients diagnosed with PC between 1999 and 2004 in Los Angeles County were identified using the Los Angeles County Cancer Registry as part of the California Collaborative Prostate Cancer study, a multiethnic, population based case-control study. Included in this analysis were 1232 men with PC: 631 with advanced stage PC at diagnosis and 430 with high-grade PC. The ethnic breakdown was 376 African-American, 355 Hispanic and 501 Caucasian. DNA was extracted from blood and genotypes for LHR, LHRHR, AR and SHBG were assayed using TaqMan or GeneScan methods. Vital status and cause of death was obtained by linking to the Cancer Registry records. Hazard ratios were estimated by fitting Cox proportional hazards models. Results: As of September 2010, 396 (32%) had died and 122 (10%) had died of PC. In the multivariate model, there was a significant association between disease specific survival and genetic variation in LHRHR, LHR and SHBG. Hazard ratios (HR) for carriers (vs. non-carriers) of the LHR312 minor allele were 1.63 (95% CI: 1.08-2.45) among all cases and 2.04 (1.23-3.39) for high- grade cases. The LHRHR16 minor allele was rare among African Americans; the HR among Caucasians was 1.90 (1.15-3.13) and did not vary by disease grade. The SHGB356 minor allele was associated with survival only among high-grade cases with a HR of 2.38 (1.18-4.81). In addition, when comparing cases to controls, the LHR312 minor allele was inversely associated with PC incidence. Conclusions: Genetic variation in the LHRHR, LHR and SHGB genes are associated with PC survival and warrant further analysis to define their role as prognostic and predictive markers. No significant financial relationships to disclose.

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Paavola, Timo, Ulrich Bergmann, Sanna Kuusisto, Sakari Kakko, Markku J. Savolainen, and Tuire Salonurmi. "Distinct Fatty Acid Compositions of HDL Phospholipids Are Characteristic of Metabolic Syndrome and Premature Coronary Heart Disease—Family Study." International Journal of Molecular Sciences 22, no. 9 (May 6, 2021): 4908. http://dx.doi.org/10.3390/ijms22094908.

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HDL particles can be structurally modified in atherosclerotic disorders associated with low HDL cholesterol level (HDL-C). We studied whether the lipidome of the main phosphatidylcholine (PC), lysophosphatidylcholine (LPC) and sphingomyelin (SM) species of HDL2 and HDL3 subfractions is associated with premature coronary heart disease (CHD) or metabolic syndrome (MetS) in families where common low HDL-C predisposes to premature CHD. The lipidome was analyzed by LC-MS. Lysophosphatidylcholines were depleted of linoleic acid relative to more saturated and shorter-chained acids containing species in MetS compared with non-affected subjects: the ratio of palmitic to linoleic acid was elevated by more than 30%. A minor PC (16:0/16:1) was elevated (28–40%) in MetS. The contents of oleic acid containing PCs were elevated relative to linoleic acid containing PCs in MetS; the ratio of PC (16:0/18:1) to PC (16:0/18:2) was elevated by 11–16%. Certain PC and SM ratios, e.g., PC (18:0/20:3) to PC (16:0/18:2) and a minor SM 36:2 to an abundant SM 34:1, were higher (11–36%) in MetS and CHD. The fatty acid composition of certain LPCs and PCs displayed a characteristic pattern in MetS, enriched with palmitic, palmitoleic or oleic acids relative to linoleic acid. Certain PC and SM ratios related consistently to CHD and MetS.

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Tong, Ming-for, and Arnis Kuksis. "Effect of different neutral phospholipids on apolipoprotein binding by artificial lipid particles in vivo." Biochemistry and Cell Biology 64, no. 8 (August 1, 1986): 826–35. http://dx.doi.org/10.1139/o86-111.

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Soybean triacylglycerol particles, stabilized with egg yolk sphingomyelin (SPH), phosphatidylcholine (PC), phosphatidylethanolamine (PE), or PC–PE mixtures, with diameters ranging from 170 to 550 nm were prepared by sonication and isolated by ultracentrifugation. Binding of apoproteins to the lipid particles was studied in vivo using the strategy of Connelly and Kuksis. The recoveries of the injected particles, which had decreased in size and undergone minimal changes in lipid composition, ranged from 70% and 57% for SPH- and PC-stabilized particles to 14% for particles stabilized with egg yolk PC–PE mixtures. The apoprotein (apo) composition of the recovered particles showed qualitative and quantitative differences, which were affected by the number of washes during isolation. After four washes, the SPH and PC particles contained apoE, apoC-II, and apoC-III as major components and apoA-IV as minor components. In addition, all particles, except those stabilized with egg yolk PC, contained large amounts of albumin. In contrast to egg yolk PC, the dipalmitoyl PC particles bound albumin as a major component. The recovered PC-PE and PE particles were characterized by a relative decrease of apoC and greatly increased binding of albumin. The higher rate of clearance of the PE-containing particles was attributed to a relative absence of apoC-III, which is known to delay hepatic uptake of lipid particles containing it, and to a more rapid hydrolysis of PE by lipoprotein lipases. Since PE occurs as a minor and variable component of chylomicrons and plasma lipoproteins, the present observations are of physiological interest.

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Marlar, Richard. "The Protein C System – How Complex Is it?" Thrombosis and Haemostasis 85, no. 05 (2001): 756–57. http://dx.doi.org/10.1055/s-0037-1615712.

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SummarySince the initial discovery of activated protein C (APC) and protein C (PC), subsequent findings have demonstrated that the protein C anti-thrombotic mechanism (anticoagulant and profibrinolytic) is very complex and convoluted, involving a multitude of other proteins and interactions with cell surfaces (1, 2). The PC system may be as complex as the coagulation scheme and other defense mechanisms. In recent years, investigations into ancillary functions of the PC system have identified interactions with some of these defense mechanisms in particular the inflammatory response (1, 3). Investigation of this highly complex system is no simple task.The number of proteins directly or indirectly involved in the PC system is growing, with several playing dual roles in the presence or absence of cells (1-5). Because of its complexity, the PC system can be broken down into functional subsets: cell-surface activation of protein C, the anticoagulant mechanism, the long-recognized but poorly-understood fibrinolytic response, and the shutdown mechanisms of the PC system. In the analysis of in vitro mechanisms of the PC pathway, care must be taken in the final interpretation of and application to the in vivo activities. We must weigh the importance of the apparent “minor” interactions with the perceived “major” roles these proteins play (5, 6). Any cursory review of these functions delineates the complexity of the system as a whole. The complex nature of the PC system reinforces how important good research is to the realization of our understanding of this functioning system. Because of the complexity of the system, the following questions must be meticulously addressed: What is the importance of each of the interactions? And what is the physiological role of these seemingly “minor” interactions of components in the regulation of the PC system?

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Widowati, I. Gusti Ayu Rai, and Mohammad Zamroni. "Indonesia Facing Challenges of Pharmaceutical Care Implementation in Community Pharmacies: A Legal Perspective." Jurnal Hukum Prasada 10, no. 2 (October 2, 2023): 69–79. http://dx.doi.org/10.22225/jhp.10.2.2023.69-79.

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Pharmaceutical Care (PC) is a kind of interactive comprehensive service offered by the pharmacist to the patient, in which the pharmacist's physical presence is expected when providing pharmaceutical services to the patients at the pharmacy. However, pharmacists still prioritized internal management over interacting directly with patients. The objective of this research is to glance at the legal challenges of PC implementation in Indonesian community pharmacies. The normative juridical research method has been used, with a conceptual and legal approach. PC implementation in community pharmacies experiences major-level, mid-level, and minor-level challenges. PC standards in pharmacies are legally stated in Regulation of the Minister of Health of the Republic of Indonesia No. 73 of 2016, but there are still conflicts between pharmaceutical management and PC implementation. In the incident of a medication error, the pharmacist as the person responsible for PC in the pharmacy, is legally responsible. Pharmacists who do not meet PC standards in community pharmacies encounter administrative, civil, and criminal consequences.

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Vakil, Meenal, and John F. Kearney. "Functional Relationship Between T15 and J558 Idiotypes in BALB/c Mice." Developmental Immunology 1, no. 3 (1991): 213–24. http://dx.doi.org/10.1155/1991/91729.

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In inbred strains of mice, antiphosphorylcholine (PC) and anti-α1,3 dextran (DEX). antibodies are structurally distinct from each other and have been shown to exhibit noncrossreactive antigen binding and idiotypic specificities. However, the prototype anti-PC and anti-DEX antibodies, TEPC15 and J558, respectively, were shown to be connected via a common autoantiidiotypic monoclonal antibody isolated from newborn BALB/c mice. The capacity of various monoclonal anti-PC and anti-DEX antibodies as well as the antigens PC and DEX to modulate T15 and J558 idiotypes in BALB/c mice was tested by their administration to newborn mice. Anti-PC antibodies of the .T15 idiotype injected into 2-4-day-old mice, at a time when T15 anti-PC precursors develop in BALB/c mice, suppressed the anti- PC response of these mice at 6 weeks of age. Similarly, J558 antibodies injected into 8-12-day-old mice, at a time when J558 precursors normally develop, suppressed the response to DEX. As a further demonstration of this connectivity, the injection of J558 into 4-day-old mice led to a down modulation of T15 idiotype, whereas both T15 and a minor idiotypeexpressing antibody M167 when injected into 8-12-day-old mice caused a reduction in expression of the J558 idiotype. As predicted from in vitro analysis, injection of anti-PC antibodies of the M167 idiotype 2 to 4 days after birth enhanced the subsequent response to PC. However, anti-PC antibodies expressing another minor M603 idiotype did not affect the PC. response. The results parallel thein vitroenhancement of M167 antibodies but not M603 on T15 binding to antiidiotypein vitro. Similarly, anti-DEX antibodies expressing the M104E idiotype had no detectable effects on the capacity to respond to PC or DEX or on the expression of T15 and J558 idiotypes as adults. Exposure of newborn mice to PC led to a dramatic reduction in the response to DEX as adults, whereas exposure to DEX at this stage of development had no effect on response to PC as adults. Collectively, these observations provide evidence for a complex functional connectivity between T15 and J558 idiotype-bearing B cells during ontogeny and extend our previous observations that development of these idiotypes is regulated by idiotype-directed interactions between B cells or their immunoglobulin products.

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Tsaulwayo, Nokwanda, Reinner O. Omondi, Paranthaman Vijayan, Nicole R. S. Sibuyi, Miché D. Meyer, Mervin Meyer, and Stephen O. Ojwach. "Heterocyclic (pyrazine)carboxamide Ru(ii) complexes: structural, experimental and theoretical studies of interactions with biomolecules and cytotoxicity." RSC Advances 14, no. 12 (2024): 8322–30. http://dx.doi.org/10.1039/d4ra00525b.

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The heterocyclic (pyrazine)carboxamide Ru(ii) complexes interact with CT-DNA through minor groove binding and partial intercalation modes and exhibit significant cytotoxicity and selectivity against A549, PC-3, and Caco-2 cell lines.

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Litvin, A. A., S. V. Korenev, E. N. Kolokoltseva, V. S. Denisyuk, and S. B. Rumovskaya. "Biological diagnostic markers and pancreatic cancer risk factors in patients with chronic pancreatitis (literature review)." Herald of Pancreatic Club 46, no. 1 (March 26, 2020): 6–11. http://dx.doi.org/10.33149/vkp.2020.01.01.

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Pancreatic cancer (PC) prevalence has steadily increased in recent years. It is untimely diagnosed due to prolonged asymptomatic course, minor changes in routine laboratory indices, lack of informative value of standard visualizing techniques. In this regard, attention is paid to determination of PC risk factors and establishment of biomarkers (diagnostic, prognostic, predictive) for pancreatic neoplastic transformation on the background of chronic pancreatitis. Non-inherited PC risk factors include old age, smoking, chronic pancreatitis, Helicobacter pylori/hepatitis B virus infection, obesity, diabetes mellitus. PC family history, family adenomatous polyposis, carriage of mutant genes (PRSS1, SPINK1, BRCA2) dominate among hereditary risk factors. Biomarkers can be used not only for early non-invasive diagnosis of PC, but also for differential diagnosis between chronic pancreatitis and PC. Sensitivity and specificity of various PC serum markers, such as CA19-9, PAM4, MIC-1, are analyzed in the article. It is possible to distinguish PC from autoimmune pancreatitis by determining the serum concentration of IgG4. In addition to blood serum, fecal masses (K-RAS, BMP3) and saliva (KRAS, MBD3L2, ACRV1 and DPM1) can be used to determine the potential markers of PC. New data of determination the fecal miRNAs as PC cancer biomarkers are presented, namely miR-21, miR-155 and miR-216. Majority of PC biomarkers have not been introduced into a routine clinical practice yet, and research on their informative value is ongoing.

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Wang, Zhengdong, Adam Foye, Yusuo Chang, Patricia R. Chess, Terry W. Wright, Samir Bhagwat, Francis Gigliotti, and Robert H. Notter. "Inhibition of surfactant activity byPneumocystis cariniiorganisms and components in vitro." American Journal of Physiology-Lung Cellular and Molecular Physiology 288, no. 6 (June 2005): L1124—L1131. http://dx.doi.org/10.1152/ajplung.00453.2004.

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This study examines the direct inhibitory effects of Pneumocystis carinii ( Pc) organisms and chemical components on the surface activity and composition of whole calf lung surfactant (WLS) and calf lung surfactant extract (CLSE) in vitro. Incubation of WLS suspensions with intact Pc organisms (107per milligram of surfactant phospholipid) did not significantly alter total phospholipid levels or surfactant protein A content. Incubation with intact Pc organisms also did not impair dynamic surface tension lowering in suspensions of WLS or centrifuged large surfactant aggregates on a bubble surfactometer (37°C, 20 cycles/min, 0.5 and 2.5 mg phospholipid/ml). However, exposure of WLS or CLSE to disrupted (sonicated) Pc organisms led to severe detriments in activity, with minimum surface tensions of 17–19 mN/m vs. <1 mN/m for surfactants alone. Extracted hydrophobic chemical components from Pc (98.8% lipids, 0.1 mM) reduced the surface activity of WLS and CLSE similarly to sonicated Pc organisms, whereas extracted hydrophilic chemical components from Pc (primarily proteins) had only minor effects on surface tension lowering. These results indicate that in addition to surfactant dysfunction induced by inflammatory lung injury and edema-derived inhibitors in Pc pneumonia, disrupted Pc organisms in the alveolar lumen also have the potential to directly inhibit endogenous and exogenous lung surfactants in affected patients.

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Rieger, M., G. Endler, M. Funk, W. Lalouschek, W. Lang, R. Sunder-Plassmann, and C. Mannhalter. "Evaluation of the PC-1 K121Q and G2906C variants as independent risk factors for ischaemic stroke." Hämostaseologie 31, no. 03 (2011): 196–200. http://dx.doi.org/10.5482/ha-1142.

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SummaryOverexpression of plasma cell membrane glycoprotein-1 (PC-1) inhibits insulin receptor tyrosine kinase activity and thus favours insulin resistance and atherosclerotic vascular disease. Recent findings indicate that the minor variant K121Q in the PC-1 gene confers an increased risk for early myocardial infarction independent of other established risk factors. We hypothesized that genetic variants in PC-1 may also influence the risk for cerebrovascular disease.Therefore, we assessed the association of the PC-1 K121Q variant in the coding region and a polymorphism (G2906C) in the 3’ untranslated region of the PC-1 gene with the risk of stroke.We analyzed 1014 patients with a history of ischaemic stroke from the Vienna stroke registry and 1001 control individuals without vascular disease.Genotype frequencies of both genetic variants were similar in patients and controls in the total study population. By multivariate analysis, no interactions were observed between the PC-1 genotype and established vascular risk factors. However, the PC-1 2906C allele was significantly more frequent in patients who suffered from stroke before the age of 40 years. In these patients the risk for ischaemic stroke was increased fourfold.

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Dissertations / Theses on the topic "Pc-Minor"

Philibert, Manon. "Cubes partiels : complétion, compression, plongement." Electronic Thesis or Diss., Aix-Marseille, 2021. http://www.theses.fr/2021AIXM0403.

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Les sous-graphes isométriques d'hypercubes (dit cubes partiels) constituent une classe centrale de la théorie métrique des graphes. Ils englobent des familles de graphes importantes (arbres, graphes médians, etc.), provenant de différents domaines de recherche, tels que la géométrie discrète, la combinatoire ou la théorie géométrique des groupes. Nous étudions tout d'abord la structure des cubes partiels de VC-dimension 2. Nous montrons que ces graphes peuvent être obtenus par amalgamations à partir de deux types de cellules combinatoires.Cette décomposition nous permet d’obtenir diverses caractérisations. En particulier, tout cube partiel de VC-dimension 2 peut être complété en cube partiel ample de VC-dimension 2. Nous montrons ensuite que les graphes de topes des matroïdes orientés et des complexes de matroïdes orientés uniformes peuvent aussi être complétés en cubes partiels amples de même VC-dimension.En utilisant un résultat de Moran et Warmuth, nous établissons que ces classes vérifient la conjecture de Floyd et Warmuth, l'une des plus vielles conjectures en théorie de l'apprentissage. C'est-à-dire qu'elles admettent des schémas de compression (étiquetés non propres) de taille leur VC-dimension.Par la suite, nous décrivons un schéma de compression étiqueté propre de taille d pour les complexes de matroïdes orientés de VC-dimension d, généralisant ainsi le résultat de Moran et Warmuth pour les amples. Enfin, nous fournissons une caractérisation par pc-mineurs exclus et parsous-graphes isométriques interdits des cubes partiels plongeables isométriquement dans la grille Z^2 et dans le cylindre P_n \square C_{2k} pour un certain n et k > 4
Partial cubes (aka isometric subgraphs of hypercubes) are a fundamental class of metric graph theory. They comprise many important graph classes (trees, median graphs, tope graphs of complexes of oriented matroids, etc.), arising from different areas of research such as discrete geometry, combinatorics or geometric group theory.First, we investigate the structure of partial cubes of VC-dimension 2. We show that those graphs can be obtained via amalgams from even cycles and full subdivisions of complete graphs. This decomposition allows us to obtain various characterizations. In particular, any partial cube can be completed to an ample partial cube of VC-dimension 2. Then, we show that the tope graphs of oriented matroids and complexes of uniform oriented matroids can also be completed to ample partial cubes of the same VC-dimension.Using a result of Moran and Warmuth, we establish that those classes satisfy the conjecture of Floyd and Warmuth, one of the oldest open problems in computational machine learning. Particularly, they admit (improper labeled) compression schemes of size their VC-dimension.Next, we describe a proper labeled compression scheme of size d for complexes of oriented matroids of VC-dimension d, generalizing the result of Moran and Warmuth for ample sets. Finally, we give a characterization via excluded pc-minors and via forbidden isometric subgraphs of partial cubes isometrically embedded into the grid \mathbb{Z}^2 and the cylinder P_n \square C_{2k} for some n and k > 4

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Book chapters on the topic "Pc-Minor"

Joordens, Matthew. "Teaching with a Tablet PC." In Mobile Devices in Education, 721–36. IGI Global, 2020. http://dx.doi.org/10.4018/978-1-7998-1757-4.ch042.

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The modern Tablet PC, such as the Surface Pro® is a flexible teaching tool. It can be used to increase the lecturer's productivity in note taking and in assignment marking. It can be used in the lecture room with increased interaction. With a few minor accessories it can be used to record many aspects of a lecture or presentation. It can also be used to record short topic segments that can be used as references or summaries by students. Containing the abilities of both a tablet device with multi touch, a pen interface for accurate drawing and handwriting and with the power of a full PC, it is a complete teaching studio.

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Lacity, Mary Cecelia, and Leslie P. Willcocks. "Survey of IT Outstanding Experiences in US and UK Organizations." In Advances in Global Information Management, 160–89. IGI Global, 2002. http://dx.doi.org/10.4018/978-1-930708-43-3.ch012.

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The global IT outsourcing market is estimated to exceed $121 billion by the year 2001. To assess current market practices and experiences, a survey was distributed to 600 US and UK CIOs. The 101 US and UK respondents are generally pleased with information technology (IT) outsourcing. In particular, respondents rated overall supplier performance as “good,” respondents mostly realized the benefits they expected from IT outsourcing, and respondents characterized the majority of problems/issues as only “minor” in nature. The healthy IT outsourcing report card is likely explained by the scope and type of IT outsourcing practiced by responding organizations. The vast majority of respondents pursue selective outsourcing which is less risky than total outsourcing. Most respondents also use multiple suppliers rather than a single supplier, which allows for best-of-breed supplier selection. The healthy report card may also be explained by the types of IT activities selected for outsourcing. Respondents generally targeted IT infrastructure activities—such as disaster recovery, mainframe operations, network management, midrange operations, PC support, and help desk operations—rather than IT development or IT strategy. UK and US practices and outcomes were very similar, although a few exceptions are noteworthy. On average, UK organizations (30%) totally insourced IT more frequently than US organizations (8%). US organizations (29%) more frequently used a single supplier than UK organizations (9%). UK organizations (50%) use only one stakeholder to negotiate/define contracts compared to US organizations (9%). Differences may be explained by a more matured approach to outsourcing in the USA together with the higher preponderance of larger deals and organizations studied. Findings are compared to prior survey and case study research.

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"Chung and Ohm triterpene alcohols including 4,4'-dimethylsterols, which is germ and aleurone fractions (Table 25). Germs are the substantially higher than those in corn oil and wheat germ richest source of lipids among all cereal grain fractions, oil [126,127,129]. even though they are relatively small fractions of grain Kuroda et al. [128] analyzed SE, S, SG, and ASG of kernels. The weight percentage of germ is 10-14% of corn, bran separately (Table 22). The 4-methylsterols and triter-8-12% of sorghum, 7% of oats, 2-4% of wheat and 1-2% pene alcohols with 4,4'-dimethylsterol were found along of rice kernel weights. with the 4-demethylsterols in SE and S but not in SG or Lipids are unevenly distributed in grain fractions, and ASG. The principal FA components of SE were linoleic lipid distribution differs among grains (Table 25). In corn (58.3%), oleic (30.4%), and palmitic (7.4%) acids, where-kernels, 73-85% of the lipid is distributed in the germ frac-as those of ASG were linoleic (42.5%), palmitic (29.9%), tions [137,138], whereas in rye, triticale, and wheat ker-and oleic (22.7%) acids [97]. The principal 4-demethyl-nels, 34-42% of the lipid is in the germ fraction [78]. The sterols of all flour sterol lipids (SE, S, SG, and ASG) and corn lipid distribution is quite similar despite the genetic bran oil were (3-sitosterol, campesterol, and stigmasterol differences in strains. The H51 is inbred; LG-11 is a three-(Table 22). The principal 4-monomethylsterols of bran oil way cross hybrid forage corn; both the waxy maize and and sterol lipids (SE and S) were gramisterol and citrosta-amylomaize are endosperm mutants. Amylomaize is also a dienol, and the principal 4,4'-dimethylsterols were 24-high-oil strain [9]. Price and Parsons [139] reported that methylenecycloartanol and cycloartenol. the hulless barley (Prilar) and the hulless oat (James) lipids Mahadevappa and Raina [129] reported the total sterol were distributed mainly in the bran-endosperm fractions lipid content as 149 mg in 100 g finger millet including 13 (Table 26). mg SE, 91 mg S, 25 mg SG, and 20 mg ASG. The major Among oat groat fractions, FL and TL were highest in FA, totaling 85-90%, were the same in both esterified the scutellum and BL were highest in embryonic axis sterols, but the proportions varied: palmitic, oleic, and (Table 27). Both red and white proso millet fractions con-linoleic acids comprised 24, 49, and 17% in SE and 43, 36, tained similar lipid contents except for the bran FL con-and 7% in ASG. All flour sterol lipids in finger millet con-tents, which were somewhat higher in the white than those tained 80-84% (3-sitosterol with the reminder being stig-in the red proso millets [33]. masterol [129]. The starch composition influences the lipid content of The 4-demethylsterols compose 87-98% of the total starch. High-amylose barley and corn starch contained sterols in both corn oil and wheat germ oil (Table 23). The higher FFA and LPL contents than waxy and normal types 4-demethylsterol contents were 1441 and 1425 mg in 100 (Table 28). Waxy-type starch contained lower lipid content g of corn oil and wheat germ oil, respectively [130]. The 13-than normal starchs of barley, corn, and rice (Table 28). sitosterol and campesterol are the major 4-demethylsterols in both corn oil and wheat germ oil. The major 4-B. Lipid Compositions in Various monomethylsterols are gramisterol and citrostadienol. In Grain Fractions addition, obtusifoliol is another major component in corn jor 4,4'-dimethylsterols are 24-methylenecy-Since the cereal lipid compositions are too complex to oil. The ma compare for all grains in one section, each will be dis-cloartanol and cycloartenol in corn and wheat germ oils. A cussed separately. substantial amount of 13-amyrin is present in wheat germ oil (Table 23). 1. Barley Long-term storage or heat treatment of flour [132] pro-The average compositions of NL and PL for two varieties, duces sitosterol oxides. The production of sitosterol oxides Kearney (winter type) and Prilar (spring type), are given in was investigated using wheat flour [132]. The 7-hydroxy-Table 29. In barley, like other cereal grains, NL are the ma-sitosterol of wheat flour lipid increased from 25.4 ppm af-jor class of NSTL (Table 3) and over one half of NL are TG ter 2 months storage to 245.0 ppm after storage of 36 (Table 29). The NL also contains 9.8% free sterols, 4.4% months (Table 24). SE, and 5.7% HC [139]. The two major classes of PL are PC and LPC (Table 29). The FA composition varies among lipid classes. The major FA is 18:2 for all classes except for IV. LIPIDS IN STRUCTURAL PARTS PG and PA. The "others" in Table 29 include relatively OF GRAINS small quantities of the other minor FA (12:0, 14:0, 16:1 A. Lipid Contents in Various and 20:0) [142,143]. Grain Fractions The NSL contents and compositions in hulless barley (Prilar) fractions and their FA compositions of NL, GL, Endosperms are the major fractions of all cereal grains, and PL are given in Table 30. The FA composition differs and yet their lipid contents are significantly lower than depending on the structural parts of the barley kernels." In Handbook of Cereal Science and Technology, Revised and Expanded, 438–39. CRC Press, 2000. http://dx.doi.org/10.1201/9781420027228-45.

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Conference papers on the topic "Pc-Minor"

DelCasale, Catherine. "Using Interrupts on the IBM PC to Generate Major and Minor Frame Times." In SAE Aerospace Avionics Equipment and Integration Conference and Exposition. 400 Commonwealth Drive, Warrendale, PA, United States: SAE International, 1987. http://dx.doi.org/10.4271/872485.

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Naji, Ahmed, Petra Pötschke, and Amir Ameli. "Electrical Conductivity of Multifunctional Blend Composites of Polycarbonate and Polyethylene With Hybrid Fillers." In ASME 2022 Conference on Smart Materials, Adaptive Structures and Intelligent Systems. American Society of Mechanical Engineers, 2022. http://dx.doi.org/10.1115/smasis2022-97843.

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Abstract Multifunctional composites are in high demand where a material needs to simultaneously satisfy several functional requirements. Bipolar plates of polymer electrolyte membrane fuel cells are great examples of this kind, requiring very high electrical and thermal conductivities together with good mechanical properties and environmental durability. Conductive filler/polymer composites (CPCs) have shown some promise towards this application. However, achieving high levels of through-plane and in-plane electrical conductivities in CPCs while maintaining scalable processability and satisfactory level of mechanical performance is challenging. In this work, a polymeric blend system together with hybrid conductive fillers was designed, manufactured, and characterized in an attempt to obtain melt-processable, highly conductive composites. Polycarbonate (PC) and high-density polyethylene (HDPE) were employed as the blend matrix with polyethylene glycol (PEG) as the compatibilizer. Carbon nanotubes (CNT), carbon fibers (CF), and graphite (G) were utilized as the conductive fillers. The HDPE was used as the minor component of blend matrix at 30 wt.% of the major matrix PC, with PC having the better affinity to the fillers. This was done to localize the conductive fillers in the major PC component of the blend. CF and G were used in ranges of 10–30 wt. % and 30–50 wt. % of the composites, respectively. CNT and PEG were fixed at 3 wt. % and 1.5 wt. %, respectively. The composites were first compounded using a twin-screw extrusion system and the test specimens were then made using compression molding process. The results showed that due to the preferential localization of the fillers in PC component of the PC/HDPE blend, the electrical conductivities were increased by about three times, compared to that of CPCs made with PC-only matrix. Consequently, high through-plane and in-plane conductivities of 10.0 and 61.1 S/cm, respectively, were achieved, which are superior to most of the previously reported results. The findings suggest that integrating blending and hybrid filler strategies could be a promising approach towards scalable manufacturing of highly conductive CPCs for applications such as bipolar plates.

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Shioya, Ryuji, Masao Ogino, Hiroshi Kawai, and Shinobu Yoshimura. "Advanced General-Purpose Finite Element Solid Analysis System Adventure_Solid on the Earth Simulator: Its Application to Full-Scale Analysis of Nuclear Pressure Vessel." In ASME/JSME 2004 Pressure Vessels and Piping Conference. ASMEDC, 2004. http://dx.doi.org/10.1115/pvp2004-2750.

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We have been developing an advanced general-purpose computational mechanics system, named ADVENTURE, which is designed to be able to analyze a model of arbitrary shape with a 10–100 million degrees of freedom (DOFs) mesh, and additionally to enable parametric and non-parametric shape optimization. Domain-decomposition-based parallel algorithms are implemented in pre-processes (domain decomposition), main processes (system matrix assembling and solutions) and post-process (visualization), respectively. Especially the hierarchical domain decomposition method with a preconditioned iterative solver (HDDM) is adopted in one of the main modules for solid analysis, named ADVENTURE_Solid. The employed preconditioner is the Balancing Domain Decomposition (BDD) type method. The ADVENTURE_Solid has been successfully implemented on a single PC, PC clusters and massively parallel processors such as Hitachi SR8000/MPP. In this study, this solid analysis module is implemented with minor modification on the Earth Simulator consisting of 256 nodes, i.e. 2,048 vector-type processing elements of theoretical peak performance of 16 TFLOPS (Tela FLoating point Operations Per Seconds), and succeeded in solving an elastostatic problem of a nuclear pressure vessel model of 100 million DOFs mesh in 8.5 minutes with 5.1 TFLOPS, which is 31.8% of the peak performance and over 80% parallel efficiency. As the purpose of demonstration of virtual mock-up test, the ADVENTURE_Solid is applied to solve a precise model of the ABWR vessel subjected to two kinds of loading conditions, i.e. (1) quasi-static seismic loading and (2) hydrostatic internal pressure.

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Aguilar Olivera, Albeiro, and Maye Catalina Neira Cardenas. "Ergonomic risk in nurses and caregivers due to patient care and mobilization in senior centers." In 13th International Conference on Applied Human Factors and Ergonomics (AHFE 2022). AHFE International, 2022. http://dx.doi.org/10.54941/ahfe1002663.

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This paper contains a study related to the risk and ergonomic conditions in nurses and caregivers, who are involved in care and mobilization of patients in senior centers. The results were obtained trought: mixed approach methodology and descriptive scope. Pragmatic techniques and data collection instruments were utilized too, including documentary analysis of work procedures, direct observation, photographic records, and cards adapted to senior centers of the Assistance mobilization of hospitalized patients methodology (MAPO). Among the findings, the critical activities and tasks in the care and mobilization of dependent or non-cooperative patients (NC) and semi-dependent or partially cooperative (PC) have been identified. In addition, other determinations have been made, including: lifting factors, minor aids, wheelchairs, environment and training in the facilities or wards of the senior center, and the calculation of ergonomic risk level, both for nursing staff and caregivers. In sum, this article provides the scientific community with a detailed risk panorama of a population and a work environment that has seen little attention in the literature, allowing the design and development of improvement strategies or the validation of existing ones.

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Yang, Cunwu, and Charles S. Ih. "Computer-generated holograms using a personal computer." In OSA Annual Meeting. Washington, D.C.: Optica Publishing Group, 1985. http://dx.doi.org/10.1364/oam.1985.ff1.

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Personal computers and peripherals have become very powerful and sophisticated. A CGH can now be readily made on a personal computer system. Our equipment consists of an IBM-PC, a Western Graphtec MP 1000-01 x-y plotter, and an IBM dot matrix printer. The serial port for asynchronous communication is used to transfer the data to the plotter. The parallel port is used for the printer for data or program printing. The MP 1000-01 plotter is very suitable for plotting holograms because it has a large plotting area (36 × 27 cm), adequate resolution, and best of all it has a built-in firmware spline routing for smooth curve plotting using only a few points. We have also added a switch (and an optional rom) so that the plotter can be changed from the MP-1000 to the popular HP-7475A mode. Because of the limited accuracy (and the speed, a minor factor), we have used a series expansion on the mathematical expressions to obtain the necessary precision. We have made holograms of two spherical waves. The quality of the plotting is comparable with that obtained from large computer systems. We also investigated ways to equalize the dark and white spacings so that the reconstruction efficiency will be more uniform across the hologram. This may also increase the reconstruction efficiency for a phase hologram. Experimental results and related technical problems are discussed.

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Giri, Shveta, Swati Shah, Rupinder Sekhon, and Sudhir Rawal. "Clinical outcomes of cytoreductive surgery and HIPEC in advanced and recurrent epithelial ovarian cancers with peritoneal carcinomatosis." In 16th Annual International Conference RGCON. Thieme Medical and Scientific Publishers Private Ltd., 2016. http://dx.doi.org/10.1055/s-0039-1685311.

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Introduction: The role of surgery for Peritoneal carcinomatosis (PC) has slowly evolved from palliation to potential curative intent. Attempting to remove all visible tumor deposits, “surgical cytoreduction” (CRS) was reported in 1930s for ovarian cancer and eventually became an accepted therapy with proven survival benefit. The new approach of combining CRS and Hyperthermic intraperitoneal chemotherapy (HIPEC) to treat peritoneal metastasis offer hope for long term survival in this group of patients. The risk and benefit of this approach continued to be debated. A prospective study was conducted to understand the perioperative outcomes of CRS & HIPEC. Aim: To evaluate the perioperative outcomes associated with CRS & HIPEC in Advanced and Recurrent Epithelial Ovarian Cancer with PC. Methods: Prospective analysis of patients undergoing CRS & HIPEC from November 2014 to July 2015 was done. Inclusion criteria included localized disease in peritoneal cavity, no distant metastasis and PS <2. Grade 3/4 complications from day of surgery until 30 days postoperatively were recorded. Results: We performed CRS & HIPEC in 20 patients from Nov 2014 to June 2015. HIPEC Plus regimens included Cisplatin (50 mg/m2) and Lipodox (15 mg/m2) intraperitoneally and Ifosphamide (1300 mg/m2) & Mesna (260 mg/m2) Infusion time was 90 minutes with a temperature range of 41-43 °C. Out of 20 patients 6 (30%) underwent primary debulking surgery and 14(70%) underwent secondary debulking surgery. PCI score ranged from 2-26 (mean 13.65). Mean operating time was 6.42 hrs and average blood loss was 1046 ml. Average hospital stay was 8 days and SICU stay was 4.9 days (range 3-14 days). Total 26 adverse events were observed of which grade 1 were 11 (42%), grade 2 were 8 (30%), grade were 3 (11.5%) and grade4 were 2 (8%). Most common complication was hematological (8) followed by respiratory (6), sepsis (4) renal (2), GI (2). 4 patients (5 events) developed grade3 or 4 complications in the form of septicaemia, pulmonary embolism, GI fistula of which 2 patients expited and remaining recovered although required prolonged hospitalization. Increased morbidity were observed in cases with symptomatic relapse, higher PCI score and CA 125 level higher than 250 U/ml. Most of the adverse events were grade 1 and 2 and were managed by observation only or GCSF support, transfusions and other minor interventions. The combined grade 3-4 morbidity was 20% (4out of 20) which consisted of neutropenia, infection and respiratory complications. One patient required relaparotomy and two patients expired attributed to pulmonary embolism and septicaemia respectively. Conclusion: Enthusiasm associated with improvement in survival is often dampened by increased perioperative mortality and morbidity figures and therefore CRS & HIPEC has not yet been considered standard of care by many centres. HIPEC after extensive cytoreductive surgery for ovarian cancer is a procedure whth acceptable morbidity that patients can tolerate. More follow up is needed to determinr the effect of HIPEC on survival. Till such time more data are obtained by way of larger randomised trials, this approach remains investigational.

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Baun, Daniel O., Eric H. Maslen, Carl R. Knospe, and Ronald D. Flack. "A Multiple Harmonic Open Loop Controller for Hydro/Aerodynamic Force Measurements in Rotating Machinery Using Magnetic Bearings." In ASME Turbo Expo 2001: Power for Land, Sea, and Air. American Society of Mechanical Engineers, 2001. http://dx.doi.org/10.1115/2001-gt-0023.

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Inherent in the construction of many experimental apparatus designed to measure the hydro/aerodynamic forces of rotating machinery are features that contribute undesirable parasitic forces to the measured or test forces. Typically, these parasitic forces are due to seals, drive couplings, and hydraulic and/or inertial unbalance. To obtain accurate and sensitive measurement of the hydro/aerodynamic forces in these situations, it is necessary to subtract the parasitic forces from the test forces. In general, both the test forces and the parasitic forces will be dependent on the system operating conditions including the specific motion of the rotor. Therefore, to properly remove the parasitic forces the vibration orbits and operating conditions must be the same in tests for determining the hydro/aerodynamic forces and tests for determining the parasitic forces. This, in turn, necessitates a means by which the test rotor’s motion can be accurately controlled to an arbitrarily defined trajectory. Here in, an interrupt driven multiple harmonic open loop controller was developed and implemented on a laboratory centrifugal pump rotor supported in magnetic bearings (active load cells) for this purpose. This allowed the simultaneous control of sub-harmonic, synchronous and super-harmonic rotor vibration frequencies with each frequency independently forced to some user defined orbital path. The open loop controller was implemented on a standard PC using commercially available analog input and output cards. All analog input and output functions, transformation of the position signals from the time domain to the frequency domain, and transformation of the open loop control signals from the frequency domain to the time domain were performed in an interrupt service routine. Rotor vibration was attenuated to the noise floor, vibration amplitude ≈ 0.2 μm, or forced to a user specified orbital trajectory. Between the whirl frequencies of ¼ and 2 times running speed, the orbit semi-major and semi-minor axis magnitudes were controlled to within 0.5% of the requested axis magnitudes. The ellipse angles and amplitude phase angles of the imposed orbits were within 0.3° and 1.0°, respectively, of their requested counter parts.

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Introduction: The role of surgery for peritoneal carcinomatosis (PC) has slowly evolved from palliation to potential curative intent. Attempting to remove all visible tumor deposits, “surgical cytoreduction” (CRS) was reported in 1930s for ovarian cancer and eventually became an accepted therapy with proven survival benefit. The new approach of combining CRS and hyperthermic intraperitoneal chemotherapy (HIPEC) to treat peritoneal metastasis offer hope for long term survival in this group of patients. The risk and benefit of this approach continued to be debated. A prospective study was conducted to understand the perioperative outcomes of CRS and HIPEC. Aim: To evaluate the perioperative outcomes associated with CRS and HIPEC in Advanced and Recurrent Epithelial Ovarian Cancer with PC. Method: Prospective analysis of patients undergoing CRS and HIPEC from November 2014 to July 2015 was done. Inclusion criteria included localized disease in peritoneal cavity, no distant metastasis and PS <2. Grade 3/4 complications from day of surgery until 30 days postoperatively were recorded. Results: We performed CRS and HIPEC in 20 patients from November 2014 to June 2015. HIPEC Plus regimens included Cisplatin (50 mg/m2) and Lipodox (15 mg/m2) intraperitoneally and Ifosphamide (1300 mg/m2) and Mesna (260 mg/m2). Infusion time was 90 minutes with a temperature range of 41-43°C. Out of 20 patients 6 (30%) underwent primary debulking surgery and 14 (70%) underwent secondary debulking surgery. PCI score ranged from 2-26 (mean 13.65). Mean operating time was 6.42 hrs and average blood loss was 1046 ml. Average hospital stay was 8 days and SICU stay was 4.9 days (range 3-14 days). Total 26 adverse events were observed of which grade 1 were 11 (42%), grade 2 were 8 (30%), grade were 3 (11.5%) and grade 4 were 2 (8%). Most common complication was hematological (8) followed by respiratory (6), sepsis (4) renal (2), GI (2). 4 patients (5 events) developed grade 3 or 4 complications in the form of septicaemia, pulmonary embolism, GI fistula of which 2 patients expited and remaining recovered although required prolonged hospitalization. Increased morbidity were observed in cases with symptomatic relapse, higher PCI score and CA 125 level higher than 250 U/ml. Most of the adverse events were grade 1 and 2 and were managed by observation only or GCSF support, transfusions and other minor interventions. The combined grade 3-4 morbidity was 20% (4 out of 20) which consisted of neutropenia, infection and respiratory complications. One patient required relaparotomy and two patients expired attributed to pulmonary embolism and septicaemia respectively. Conclusion: Enthusiasm associated with improvement in survival is often dampened by increased perioperative mortality and morbidity figures and therefore CRS and HIPEC has not yet been considered standard of care by many centres. HIPEC after extensive cytoreductive surgery for ovarian cancer is a procedure whth acceptable morbidity that patients can tolerate. More follow up is needed to determinr the effect of HIPEC on survival. Till such time more data are obtained by way of larger randomised trials, this approach remains investigational.

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Masson, Viviana, Nicola´s Silin, Alejandra Azcona, Dari´o Delmastro, Juan Carlos Garci´a, and Daniel Mateos. "Experimental Investigation on the Heat Transfer Characteristics of a Minichannel in Transition Flow." In 16th International Conference on Nuclear Engineering. ASMEDC, 2008. http://dx.doi.org/10.1115/icone16-48451.

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In MTR reactors the fuel elements are usually of flat plate-type and the cooling water flows through gaps of 2 to 4 mm. Therefore, correlations developed for parallel flat plates are usually used for their study. Nevertheless, in the hydrodynamic regime of transition, the flow is not stable and, under high heat fluxes, there are no reliable correlations that can be applied in this geometry. The aim of the present work is to determine experimentally the heat transfer coefficient for water in this geometry in the rank of 3000< Re <10000 and for relatively high heat fluxes (between 24 W/cm2 and 32 W/cm2). The experimental setup consists of a 200 liters water tank, pressurized to 1.7 atm, which discharges its content through the vertical test section. The flow is downwards and it is controlled by a valve located downstream. The flow rate is measured with a orifice plate connected to a DPcell and the pressure with a JUMO pressure digital sensor. The test section is a rectangular channel constructed with two 62 cm long, 6 cm wide and 6mm thickness aluminum plates, separated with Teflon strips which set the gap for the flow passage. Gaps or plate separations of 2.7 mm and 3.8 mm were studied. The aluminum plates were electrically heated from the rear using a Bruker BMN 70/700 direct current power supply. The tests were made at 18 kW and 24 kW. The wall temperatures were measured with K-type thermocouples placed in different axial positions. The temperature measurements, the DPcell signal and the pressure signal were acquired with a digital card connected to a PC. Two different inlet flow temperatures were considered 10°C and 38°C. With this arrangement, measurements of wall temperatures evolutions were obtained and the local coefficient of convection h(z) was calculated. Comparisons with turbulent correlations for flat plates indicate that the measured temperatures of wall are greater than expected. It was also observed that there are zones where subcooled boiling is reached. There are some particular aspects that could affect the reliability of correlations for flows between flat plates. The first phenomenon is the change of viscosity close to the wall due to the very high heat fluxes. There may also appear buoyancy effects, though we believe they have a minor importance. And finally the long thermal and hydrodynamic development distances, which may delay the appearance of turbulence in the channel.

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Reports on the topic "Pc-Minor"

Comparing alternative products in the provision of emergency contraception. Population Council, 1999. http://dx.doi.org/10.31899/rh1999.1010.

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This report is the third in a series of summaries produced in connection with the operations research project “Enhancing Access to Family Planning Services through the Introduction of Emergency Contraception.” Launched in September 1997, the project explores the many issues surrounding the introduction and delivery of emergency contraception services in a developing country context. The study compares the introduction of two different emergency contraception pills—the combined oral contraceptive PC-4, introduced in Zambia in 1997, and the progestin-only contraceptive Postinor-2, introduced by this study in the following year. Client histories showed only minor differences in the attitudes of emergency contraception users toward the two methods, but the study highlights important differences between the two products, some of which could have implications for service delivery.

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