Academic literature on the topic 'Pc 5'
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Journal articles on the topic "Pc 5"
Abernethy, Amy P. "PC-FACS." Journal of Pain and Symptom Management 37, no. 5 (May 2009): 934–40. http://dx.doi.org/10.1016/s0885-3924(09)00448-5.
Full textAbernethy, Amy P. "PC-FACS." Journal of Pain and Symptom Management 38, no. 2 (August 2009): 322–26. http://dx.doi.org/10.1016/s0885-3924(09)00626-5.
Full textAbernethy, Amy P. "PC-FACS." Journal of Pain and Symptom Management 40, no. 1 (July 2010): 155–61. http://dx.doi.org/10.1016/s0885-3924(10)00449-5.
Full textAbernethy, Amy P. "PC-FACS." Journal of Pain and Symptom Management 41, no. 4 (April 2011): 812–17. http://dx.doi.org/10.1016/s0885-3924(11)00151-5.
Full textAbernethy, Amy P. "PC-FACS." Journal of Pain and Symptom Management 41, no. 6 (June 2011): 1111–15. http://dx.doi.org/10.1016/s0885-3924(11)00237-5.
Full textZhukovsky, Donna S. "PC-FACS." Journal of Pain and Symptom Management 45, no. 1 (January 2013): 150–56. http://dx.doi.org/10.1016/s0885-3924(12)00830-5.
Full textZhukovsky, Donna S. "PC-FACS." Journal of Pain and Symptom Management 45, no. 2 (February 2013): 310–16. http://dx.doi.org/10.1016/s0885-3924(13)00036-5.
Full textdi. "Pilotprojekt Tablet-PC." Pflegezeitschrift 71, no. 1-2 (January 2018): 59. http://dx.doi.org/10.1007/s41906-018-0372-5.
Full textHudson, M. K., R. E. Denton, M. R. Lessard, E. G. Miftakhova, and R. R. Anderson. "A study of Pc-5 ULF oscillations." Annales Geophysicae 22, no. 1 (January 1, 2004): 289–302. http://dx.doi.org/10.5194/angeo-22-289-2004.
Full textSakurai, Tohru, Yutaka Tonegawa, Takuya Kitagawa, Kiyofumi Yumoto, Tatsundo Yamamoto, Susumu Kokubun, Toshifumi Mukai, and Koichiro Tsuruda. "Dayside magnetopause Pc 3 and Pc 5 ULF waves observed by the GEOTAIL Satellite." Earth, Planets and Space 51, no. 9 (September 1999): 965–78. http://dx.doi.org/10.1186/bf03351567.
Full textDissertations / Theses on the topic "Pc 5"
Cathebras, Gyslaine. "Appareil automatique de mesure de bruit dans la gamme 5 Mhz-800 Mhz, géré par microordinateur (IBM PC)." Montpellier 2, 1989. http://www.theses.fr/1989MON20072.
Full textBlumtritt, Clauß, Fischer, Kempe, Trapp, Richter, Wolf, and Ziegler. "Mitteilungen des URZ 2/2005." Universitätsbibliothek Chemnitz, 2005. http://nbn-resolving.de/urn:nbn:de:swb:ch1-200500395.
Full textHuamán, Bustamante Jesús Omar. "Implementación de un controlador difuso de temperatura prototipo usando la inferencia difusa de Takagi Sugeno." Universidad Nacional de Ingeniería. Programa Cybertesis PERÚ, 2007. http://cybertesis.uni.edu.pe/uni/2007/huaman_bj/html/index-frames.html.
Full textChan, Ya-Ling, and 詹雅玲. "Investigation of anticancer mechanism of LYF-5 and anthracenedione analogues in hormone- resistant prostate cancer PC-3 Cells." Thesis, 2005. http://ndltd.ncl.edu.tw/handle/89057311352352599319.
Full text國立臺灣大學
藥學研究所
93
Prostate cancer is the most frequently diagnosed malignancy in males in the United States and most other industrialized Western countries. It kills more than 30,000 American men yearly and it is one of the top 10 deadliest cancers in Taiwan. There have been no therapeutic agents that provide a survival advantage in prostate cancer. Therefore, it is necessary to develop novel agents for the treatment of hormone-refractory prostate cancer. In the first part of this study, we used human hormone-resistant prostate cancer cell line PC-3 to investigate the anti-tumor effect and mechanism of compound LYF-5 (3’-methoxyl-2-phenyl-6-methyl-1,8-naphthyridine-4-one). LYF-5 inhibited cell growth in a dose-dependent manner with an IC50 of 0.12 μM by sulforhodamine B (SRB) assays. Using FACScan flow cytometric analysis, the data showed that LYF-5 induced the arrest of cells in G2/M phase of the cell cycle and a subsequent increase of hypodiploid sub-G1 cells. The apoptotic cell death was also identified by TUNEL reaction technique. Immunofluoresence microscopic examination indicated that LYF-5 had an action target on tubulin/microtubule. Several apoptosis-related proteins were examined in this study. After the detection of expression of Bcl-2 family members by Western blotting, the data showed that LYF-5 induced phosphorylation of Bcl-2 and Bcl-xL, and Mcl-1 down-regulation. In addition, the cleaved forms of Mcl-1 was also apparent. Moreover, LYF-5-induced apoptosis was associated with processing of pro-caspase-8, pro-caspase-3 and pro-caspase-9, indicating the involvement of caspase activation. The expression of XIAP and cIAP2 were decreased after treating with LYF-5. Furthermore, we used immunofluoresence microscopic examination to examine the release reaction of cytochrome c. The data showed that LYF-5 significantly induced the release of cytochrome c from mitochondria. Taken together, it is suggested that LYF-5 induces apoptotic cell death through the target on tubulin/microtubule, the induction of mitotic arrest of the cell cycle, phosphorylation and cleavage of anti-apoptotic Bcl-2 family protein members, the activation of caspase and the release of cytochrome c. In the second part of this study, the structure-activity relationship of a series of anthracenedione derivatives on anticancer activity and their action mechanisms in human hormone-resistant prostate cancer PC-3 cells were investigated. By using SRB assays, we found that several compounds displayed anticancer activity and amongst, WRC-76 was the most effective one with an IC50 of 0.28 μM. Accordingly, WRC-76 was selected for the mechanism study. The data showed that WRC-76 induced the arrest of the cell cycle in S and G2/M phase and a subsequent increase of hypodiploid sub-G1 phase. Immunofluoresence microscopic examination indicated that WRC-76 had no effect on tubulin/microtubule function. Several apoptosis-related proteins were examined in this study. After the detection of expression of Bcl-2 family members by Western blotting, the data showed that the expression of Mcl-1 was decreased after theatment with WRC-76. Moreover, WRC-76-induced cell apoptosis was associated with processing of pro-caspase-8, pro-caspase-3 and pro-caspase-9. The expression of XIAP but not survivin was inhibited by WRC-76. Caspase-12, CHOP and GRP78 are three ER stress markers and the expression of caspase-12 and CHOP were significantly increased by WRC76. Furthermore, JNK and p38 MAP kinases involved pathways were also activated in cells responsive to WRC-76. Taken together, it is suggested that WRC-76 induces apoptotic cell death through the activation of caspase-8, -9 and -3. WRC-76 also induces the ER stress of increase of CHOP expression and caspase-12 activity. Furthermore, the activation of JNK and p38 MAPK may, at least partly, explain WRC-76-induced apoptotic cell death.
Wu, Chi, and 吳琪. "Study of CMB and G4c-f8-5-1-induced apoptotic mechanism in human prostate cancer PC-3 cells." Thesis, 2003. http://ndltd.ncl.edu.tw/handle/88162916974616887750.
Full text國立臺灣大學
藥學研究所
91
Abstract 第一部分 In search for potential anticancer drug candidates in natural products, we have carried out a large scale screening test on cytotoxic effects using MTT assay. The compound of CMB, from Cesearia sp., was the most effective one on the induction of apoptosis in human androgen-independent prostate cancer cells (PC-3). CMB induced cell apoptosis based on TUNEL-response and negative release reaction of lactate dehydrogenase (LDH). Furthermore, its cytotoxic effect was additive in combination with paclitaxel. Using Western blotting analysis, we found that CMB compound induced the release of cytochrome c from mitochrodria to cytosol and markedly induced the phosphorylation of a p38 mitogen-activated protein kinase (MAPK) in a time-dependent manner; besides, SB203580, a selective p38 MAPK inhibitor, reversed CMB compound-induced apoptosis suggesting the involvement of p38 MAPK-mediated pathway. CMB also caused the activation of caspase-3 in PC-3 cells. We examined the expression of Bcl-2 family proteins, such as Bcl-2 and Bax. CMB caused a downregulation of the expression of Bcl-2 and showed little influence on the expression of Bax. In this study, we also examined the anti-angiogenic activity of CMB in an in vivo model. The data demonstrated that CMB inhibited vascular endothelium growth factor (VEGF)-induced angiogenesis in a concentration-dependent manner. In summary, it is suggested that CMB-induced apoptosis is through a p38 MAPK-involved and Bcl-2 downregulation-cytochrome c release-caspase-3 activation signaling pathway. Abstract 第二部分 We have carried out a large anticancer screening test in numerous natural products by MTT assay. We found that several prostanoids from the Japanese stolonifer Clavularia sp., G4c-series showed effective cytotoxic activities in human androgen-independent prostate cancer cells (PC-3) and G4c-f8-5-1 was the most potent one. Besides, G4c-f8-5-1 induced cell apoptosis based on strong positive TUNEL-response. G4c-f8-5-1 triggered the lengthening of sub G1 phase of the cell cycle in a concentration- and time-dependent manner with an IC50 value of 0.5 μM. Using several pharmacological inhibitors to block biological functions, our data showed that the regulation of the generation of free radical, and the activition of p38-MAPK, protein kinase C, and Ras were not involved in the G4c-f8-5-1-induced apoptotic response. However, G4c-f8-5-1 induced a significant increase of caspase-3 activity. Furthermore, there is little alteration of the Bcl-2 protein expression level after the exposure of G4c-f8-5-1 to PC-3 cells. On the contrast, G4c-f8-5-1 caused an increase of the Bax protein expression in a concentration-dependent manner. It is suggested that G4c-f8-5-1 is the most potent prostanoid that induces apoptosis in PC-3 cells via a Bax upregulation- and caspase-3 activation-involved mechanism in this study.
Lee, Eun Ah. "Large Scale ULF Waves and Energetic Particles in the Earth's Magnetosphere." Phd thesis, 2011. http://hdl.handle.net/10048/1729.
Full textBooks on the topic "Pc 5"
McClelland, Deke. The first book of PC Paintbrush 5+. Carmel, Ind: Alpha Books, 1992.
Find full textSocha, John. PC World DOS 5 complete handbook. San Mateo, Calif: IDG Books Worldwide, 1991.
Find full textSocha, John. PC world DOS 5 complete handbook. San Mateo, Calif: IDG Books Worldwide, 1991.
Find full textProsise, Jeff. PC magazine DOS 5 techniques and utilities. Emeryville, Calif: Ziff-Davis Press, 1991.
Find full textAlkin, Oktay. PC-DSP, 5 1/4" IBM version. Englewood Cliffs, N.J: Prentice Hall, 1990.
Find full textDavid, Maguiness, ed. PC World EXCEL 5 for Windows handbook. 2nd ed. San Mateo, Ca: IDG Books, 1994.
Find full textWalkenbach, John. PC world Excel 5 for Windows handbook. 2nd ed. San Mateo, Calif: IDG Books, 1994.
Find full textBook chapters on the topic "Pc 5"
Feindor, Roland, and Christoph Ohliger. "5 Jahre Erfahrung mit der PC-Vemetzung — Eine Zwischenbilanz des Modells Rosenheim." In PC-Einsatz in der Hochschulausbildung, 56–64. Berlin, Heidelberg: Springer Berlin Heidelberg, 1992. http://dx.doi.org/10.1007/978-3-642-84839-1_10.
Full textQian, S., M. K. Hudson, and I. Roth. "Ring current 0+Interaction with PC 5 Micropulsations." In Geophysical Monograph Series, 143–50. Washington, D. C.: American Geophysical Union, 2013. http://dx.doi.org/10.1029/gm062p0143.
Full textTsakalakis, Thomas. "Alceste . . . and the Rest: A Misanthropic Pessimist’s Outlook on PC." In Political Correctness: A Sociocultural Black Hole, 119–35. 1 Edition. | New York: Routledge, 2020. |: Routledge, 2020. http://dx.doi.org/10.4324/9781003058489-5.
Full textRasinkangas, R., K. Mursula, G. Kremser, H. J. Singer, B. J. Fraser, A. Korth, and W. J. Hughes. "Simultaneous Occurrence of Pc 5 and Pc 1 Pulsations in the Dawnside Magnetosphere: CRRES Observations." In Solar Wind Sources of Magnetospheric Ultra-Low-Frequency Waves, 417–24. Washington, D. C.: American Geophysical Union, 2013. http://dx.doi.org/10.1029/gm081p0417.
Full textSternberg, U., and F. Th Koch. "COSMOS- A PC-Program for Molecular Modelling, Crystallography and the Prediction of Molecular Properties." In Software Development in Chemistry 5, 183–89. Berlin, Heidelberg: Springer Berlin Heidelberg, 1991. http://dx.doi.org/10.1007/978-3-642-76325-0_20.
Full textGante, J., W. Hechler, and R. Weitzel. "THE PHENOTHIAZINYL-(10)-CARBONYL (PC) - RESIDUE, A NOVEL AMINO-PROTECTING GROUP FOR PEPTIDE SYNTHESIS." In Porto Carras, Chalkidiki, Greece, Aug. 31–Sept. 5, 1986, edited by Dimitrios Theodoropoulos, 87–90. Berlin, Boston: De Gruyter, 1987. http://dx.doi.org/10.1515/9783110864243-017.
Full textHartmann, Guido. "Berichterstattung über CIP-Forum 5 “CIP-PC-Pools für CAD, Grafik und Desktop Publishing”." In Mikrocomputer-Pools in der Lehre, 368–70. Berlin, Heidelberg: Springer Berlin Heidelberg, 1989. http://dx.doi.org/10.1007/978-3-642-83857-6_48.
Full textSato, Natsuo, and Thorsteinn Saemundsson. "Pc 1–5 Geomagnetic Pulsations and 750 Hz ELF Activity at Ground Level in the Northern and Southern Hemispheres." In Electromagnetic Coupling in the Polar Clefts and Caps, 229–38. Dordrecht: Springer Netherlands, 1989. http://dx.doi.org/10.1007/978-94-009-0979-3_16.
Full text"The PC." In PC Based Instrumentation and Control, 17–72. Routledge, 2013. http://dx.doi.org/10.4324/9780080479903-5.
Full textMassey, Liesl K. "Polycarbonate (PC)." In The Effect of Sterilization Methods on Plastics and Elastomers, 81–109. Elsevier, 2005. http://dx.doi.org/10.1016/b978-081551505-0.50013-5.
Full textConference papers on the topic "Pc 5"
Jiang, X., K. Snook, W. S. Hackengerber, J. R. Yuan, A. Cheng, M. Schafer, and X. Geng. "4F-5 PC-MUT Arrays for Ophthalmologic Ultrasound." In 2007 IEEE Ultrasonics Symposium. IEEE, 2007. http://dx.doi.org/10.1109/ultsym.2007.88.
Full textCrowl, Steve. "Pocket PC Asset Manager using Radio Frequency Identification." In 2007 IEEE Region 5 Technical Conference. IEEE, 2007. http://dx.doi.org/10.1109/tpsd.2007.4380342.
Full textLiu Yonghua, Liu Ruiyuan, Yang Shaofeng, He Longsong, and B. J. Fraser. "Propagation characteristics of Pc 5 frequency range pulsation at cusp latitude." In Proceedings of ISAPE 2000: Fifth International Symposium on Antennas, Propagation, and EM Theory. IEEE, 2000. http://dx.doi.org/10.1109/isape.2000.894843.
Full textBelda, Kvetoslav, and Oliver Rovny. "Predictive control of 5 DOF robot arm of autonomous mobile robotic system motion control employing mathematical model of the robot arm dynamics." In 2017 21st International Conference on Process Control (PC). IEEE, 2017. http://dx.doi.org/10.1109/pc.2017.7976237.
Full textde Carvalho, V. J. O. Werneck, L. C. C. Benyosef, and A. S. de Assis. "Estudo de pulsações, Pc 5-6, em um perfil perpendicular ao dip equatorial." In 15th International Congress of the Brazilian Geophysical Society & EXPOGEF, Rio de Janeiro, Brazil, 31 July-3 August 2017. Brazilian Geophysical Society, 2017. http://dx.doi.org/10.1190/sbgf2017-333.
Full textMoon, Hyeongsun, Laura Sharpe, Eunju Choi, Helle Bielefeldt-Ohmann, Zeyad Nassar, Marie-Odile Parat, Mathias Francois, et al. "Abstract 4950: Hypercholesterolemia promotes prostate cancer PC-3 metastases in orthotopic xenograft mice." In Proceedings: AACR Annual Meeting 2014; April 5-9, 2014; San Diego, CA. American Association for Cancer Research, 2014. http://dx.doi.org/10.1158/1538-7445.am2014-4950.
Full textKUDO, Hiroshi, Rika SHINOHARA, Shunsaku TAKEISHI, Naoki AWAJI, and Masao YAMADA. "Densified SiOF Film Formation for Preventing Water Absorption." In 1995 International Conference on Solid State Devices and Materials. The Japan Society of Applied Physics, 1995. http://dx.doi.org/10.7567/ssdm.1995.pc-5-5.
Full textHashimoto, M., Y. Ohkubo, M. Shimanoe, M. Nakamura, H. Sato, H. Komatsu, and Y. Miyazawa. "A 100±15nm Thick 8-inch Bonded SOI Fabricated with a Selective Polishing Method." In 1996 International Conference on Solid State Devices and Materials. The Japan Society of Applied Physics, 1996. http://dx.doi.org/10.7567/ssdm.1996.pc-5-5.
Full textSuliman, Magdi E. Yousif, A. Yoshikawa, K. Yumoto, H. Kawano, Teiji Uozumi, S. Abe, M. G. Cardinal, Paolo Palangio, and Lynn Kaisan. "The relation between amplitudes of a global-mode Pc 5 pulsations and geosynchronous electron fluxes." In 2013 International Conference on Space Science and Communication (IconSpace). IEEE, 2013. http://dx.doi.org/10.1109/iconspace.2013.6599453.
Full textSchulz, Ulrike, Peter Munzert, Sylvelin Reinhard, Friedrich Rickelt, Heiko Knopf, Christiane Weber, and Norbert Kaiser. "Pretreatment of PC as condition for the homogeneous etching of AR-nanostructures." In Optical Interference Coatings. Washington, D.C.: OSA, 2016. http://dx.doi.org/10.1364/oic.2016.fb.5.
Full textReports on the topic "Pc 5"
Cheng, C. Z., Q. Qian, K. Takahashi, and A. T. Y. Lui. Ballooning-mirror instability and internally driven Pc 4--5 wave events. Office of Scientific and Technical Information (OSTI), March 1994. http://dx.doi.org/10.2172/142542.
Full textGrimesey, R., D. Nigg, and R. Curtis. COMBINE/PC: A portable ENDF/B Version 5 neutron spectrum and cross-section generation program. Office of Scientific and Technical Information (OSTI), April 1990. http://dx.doi.org/10.2172/7161236.
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