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Dissertations / Theses on the topic 'PBD'

Author: Grafiati
Published: 4 June 2021
Last updated: 25 July 2025

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1

Smellie, Melissa. "Molecular and cellular pharmacology of rationally designed PBD dimers." Thesis, University of Portsmouth, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.261402.

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2

Burger, A. M., Paul M. Loadman, D. E. Thurston, R. Schultz, H. H. Fiebig, and Michael C. Bibby. "Preclinical pharmacology of the pyrrolobenzodiazepine (PBD) monomer DRH-417 (NSC 709119)." Italian Society of Chemotherapy and the Italian Federation of Human and Animal Mycopathology, 2007. http://hdl.handle.net/10454/4571.

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no<br>The pyrrolobenzodiazepine monomer DRH-417 is a member of the anthramycin group of anti-tumor antibiotics that bind covalently to the N2 of guanine within the minor groove of DNA. DRH-417 emerged from the EORTC-Drug Discovery Committee and NCI 60 cell line in vitro screening programs as a potent antiproliferative agent with differential sensitivity towards certain cancer types such as melanoma, breast and renal cell carcinoma (mean IC(50) = 3 nM). DRH-417 was therefore tested for in vivo activity. The maximum tolerated dose (MTD) was established as 0.5 mg/kg given i.p. Marked anti-tumor a
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3

Chrisospathis, Aristomenis 1969. "A new approach in blade shape adjustment in PBD-14 design mode." Thesis, Massachusetts Institute of Technology, 2001. http://hdl.handle.net/1721.1/8606.

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Thesis (S.M. and Nav.E.)--Massachusetts Institute of Technology, Dept. of Ocean Engineering, 2001.<br>Includes bibliographical references (leaves 68-70).<br>The purpose of this study is to develop a more efficient and robust algorithm for adjusting the blade shape as a part of a coupled lifting-surface design/analysis code for marine propulsors developed at MIT, known as PBD-14. The algorithm for adjusting the blade shape in the current version of PBD-14 works satisfactorily in most cases. However, with more complex schemes such as ducted propulsors and/or higher load distributions, the proces
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4

Hipps, Henry. "Developing a continuous emulsion PBD-Graft-SAN polymerization process: factors for morphology control." Thesis, Georgia Institute of Technology, 1998. http://hdl.handle.net/1853/10973.

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5

Gamom, Ngounou Ewo Roland Christian. "Déploiement d'applications parallèles sur une architecture distribuée matériellement reconfigurable." Thesis, Cergy-Pontoise, 2015. http://www.theses.fr/2015CERG0773/document.

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Parmi les cibles architecturales susceptibles d'être utilisées pour réaliser un système de traitement sur puce (SoC), les architectures reconfigurables dynamiquement (ARD) offrent un potentiel de flexibilité et de dynamicité intéressant. Cependant ce potentiel est encore difficile à exploiter pour réaliser des applications massivement parallèles sur puce. Dans nos travaux nous avons recensé et analysé les solutions actuellement proposées pour utiliser les ARD et nous avons constaté leurs limites parmi lesquelles : l'utilisation d'une technologie particulière ou d'architecture propriétaire, l'a
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6

Kaliszczak, Maciej. "Rational design of pyrrolobenzodiazepine derivatives." Thesis, University of Edinburgh, 2009. http://hdl.handle.net/1842/4923.

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Pyrrolobenzodiazepine (PBD) derivatives interact with the minor-groove of DNA to form mono-adducts (monomers) or cross-links (dimers). They show remarkable activity in vitro and in vivo in a wide range of tumour types and one dimer, SJG-136 is currently in clinical development. Preclinical studies have shown that SJG-136 is a P-gp substrate limiting its anti-tumour activity. The work presented in this thesis identifies key physicochemical properties influencing both the interaction of PBDs with ABC transporters P-gp, MRP1 and BCRP and their growth inhibitory potency. A testable hypothesis for
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7

Hai, Bin. "Development and Implementation of New In Situ Techniques for the Study of Interfacial Phenomena." Case Western Reserve University School of Graduate Studies / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=case1259695728.

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8

Hawkins, Rachel Marina. "Design, synthesis and biological evaluation of novel PBD-heterocycle and conjugates as potential transcription factor binding inhibitors." Thesis, University College London (University of London), 2007. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.498774.

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9

Lobo, Junior Marco Aurélio. "Design para a competitividade no Brasil: o caso do Projeto Design Export." reponame:Repositório Institucional da UnB, 2017. http://repositorio.unb.br/handle/10482/23983.

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Dissertação (mestrado)—Universidade de Brasília, Instituto de Artes, Programa de Pós-Graduação em Design, 2017.<br>Submitted by Raquel Almeida (raquel.df13@gmail.com) on 2017-07-10T20:58:23Z No. of bitstreams: 1 2017_MarcoAurélioLoboJunior.pdf: 2897522 bytes, checksum: a5317ddbbd7608a6c09f80a610a74df4 (MD5)<br>Approved for entry into archive by Raquel Viana (raquelviana@bce.unb.br) on 2017-07-31T21:42:52Z (GMT) No. of bitstreams: 1 2017_MarcoAurélioLoboJunior.pdf: 2897522 bytes, checksum: a5317ddbbd7608a6c09f80a610a74df4 (MD5)<br>Made available in DSpace on 2017-07-31T21:42:52Z (GMT). No. of b
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10

Thompson, Thaddeus. "Rheological Study of Linear and Nonlinear Viscoelastic Behavior for Silica-Reinforced Polybutadiene and Polystyrene." University of Akron / OhioLINK, 2005. http://rave.ohiolink.edu/etdc/view?acc_num=akron1134566032.

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11

GONZALEZ, GONZALEZ JUVENAL 629192, and GONZALEZ JUVENAL GONZALEZ. "Detección de éter etílico en mezcla con etanol empleando compuestos poliméricos a base de polivinilpirrolidona (pvp), polibutadieno (pbd) y negro de carbono." Tesis de maestría, Universidad Autónoma del Estado de México, 2016. http://hdl.handle.net/20.500.11799/66101.

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GONZALEZ, GONZALEZ JUVENAL 629192, and GONZALEZ JUVENAL GONZALEZ. "Detección de éter etílico en mezcla con etanol empleando compuestos poliméricos a base de Polivinilpirrolidona (PVP), Polibutadieno (PBD) y Negro de Carbono." Tesis de maestría, UAEM, 2016. http://hdl.handle.net/20.500.11799/66120.

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13

Stenlund, Anna, Sanna Sjöström, and Cecilia Wännberg. "PRIVACY BY DESIGN likheter och skillnader mellan leverantörer och betällare : En studie med fokus på inställning, kunskap och utmaningar." Thesis, Umeå universitet, Institutionen för informatik, 2018. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-148135.

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The EU General Data Protection Regulation (GDPR) replaces the Data Protection Directive 95/46/EC in May 25, 2018. This will generate major changes for organizations that process personal data. Privacy by Design is a requirement in GDPR and a concept that implies that IT systems are designed in such way that personal privacy is protected. By taking early consideration of Privacy by Design in procurement of IT, public organizations can ensure that integrity requirements are met and that privacy is protected. This study aims at studying differences between clients from public sector and IT provid
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14

Saell, Franziska. "Female and male audiences' perception on a plant-based (Vegan) diet after having viewed the documentary film What the Health : How perception on a plant-based diet (Vegan) changes after having watched the documentary film What the Health." Thesis, Högskolan för lärande och kommunikation, Jönköping University, HLK, Medie- och kommunikationsvetenskap, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:hj:diva-48296.

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Veganism (or following a PBD) is scientifically proven to be one of the possible answers to the environmental, ethical and health issues our society is currently facing. The documentary film What the Health advocates this claim and presents the tremendous impacts, meat and dairy production and consumption, have on our environment, our personal health and for the people living on our planet. The documentary’s attempt of persuading people to adopt a PBD remained unanswered and was the chosen case-study for this research on audience reception and media effects. The purpose of this research is to
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15

Errami, Jalal. "Modelling DNA Hairpins." Lyon, École normale supérieure (sciences), 2007. http://www.theses.fr/2007ENSL0403.

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Les « DNA beacons » sont des molécules composées de simple brins d'ADN dont les deux bouts contiennent des bases complémentaires et auxquels on attache un fluorophore et un quencher. Ainsi, ces deux extrémités peuvent s'assembler pour former un bout de double hélice d'ADN que nous appelons « stem », la partie centrale du brin forme alors une sorte de boucle. On appelle cette structure la configuration en « épingle à cheveux ». Un aspect important de cette structure est qu'elle représente des systèmes simples permettant une étude détaillée de l'assemblage/désassemblage de la double hélice d'ADN
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16

Jarrett, John M. "Synthesis and In-Vitro Cell Viability/Cytotoxicity Studies of Novel Pyrrolobenzodiazepine Derivatives." Digital Commons @ East Tennessee State University, 2017. https://dc.etsu.edu/honors/361.

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Pyrrolobenzodiazepines (PBDs) are a group of naturally occurring compounds that were discovered in the cultures of Streptomyces in the 1960s. Some natural PBDs discovered in these cultures, such as anthramycin and sibiromycin, were shown to possess a broad spectrum of anti-tumor activity. Since cancer is still a leading cause of death globally, the development of novel anti-proliferative derivatives of PBDs is essential for human welfare worldwide. Further synthesis and structure-activity relationship (SAR) studies of the parent natural products and their tetracyclic analogs will lead to the d
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17

Maxwell, Megan Amanda, and n/a. "PEX1 Mutations in Australasian Patients with Disorders of Peroxisome Biogenesis." Griffith University. School of Biomolecular and Biomedical Science, 2004. http://www4.gu.edu.au:8080/adt-root/public/adt-QGU20040219.100649.

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The peroxisome is a subcellular organelle that carries out a diverse range of metabolic functions, including the b-oxidation of very long chain fatty acids, the breakdown of peroxide and the a-oxidation of fatty acids. Disruption of peroxisome metabolic functions leads to severe disease in humans. These diseases can be broadly grouped into two categories: those in which a single enzyme is defective, and those known as the peroxisome biogenesis disorders (PBDs), which result from a generalised failure to import peroxisomal matrix proteins (and consequently result in disruption of multiple metab
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18

Maxwell, Megan Amanda. "PEX1 Mutations in Australasian Patients with Disorders of Peroxisome Biogenesis." Thesis, Griffith University, 2004. http://hdl.handle.net/10072/366184.

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The peroxisome is a subcellular organelle that carries out a diverse range of metabolic functions, including the b-oxidation of very long chain fatty acids, the breakdown of peroxide and the a-oxidation of fatty acids. Disruption of peroxisome metabolic functions leads to severe disease in humans. These diseases can be broadly grouped into two categories: those in which a single enzyme is defective, and those known as the peroxisome biogenesis disorders (PBDs), which result from a generalised failure to import peroxisomal matrix proteins (and consequently result in disruption of multiple metab
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19

Follet-Houttemane, Claudine. "Les Phases oxyfluorées du système BiO-Pbo-PbF stabilité-propriétés électriques, caractéristiques structurales /." Grenoble 2 : ANRT, 1987. http://catalogue.bnf.fr/ark:/12148/cb376051434.

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20

Mingle, David. "Synthesis, Characterization and Biological Evaluation of Novel (S,E)-11-[2-(Arylmethylene) Hydrazono] Pyrrolo [2,1-c] [1,4] Benzodiazepine Derivatives." Digital Commons @ East Tennessee State University, 2019. https://dc.etsu.edu/etd/3596.

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Pyrrolo [2,1-c] [1,4] benzodiazepine (PBD) is a class of natural products obtained from various actinomycetes which have both anti-tumor and antibiotic activities and can bind to specific sequences of DNA. PBD-dilactam was initially produced using isatoic anhydride and (L)-proline which was then converted to the PBD-thiolactam using Lawesson's reagent. Reaction of thiolactam with hydrazine in ethanol afforded PBD-11-hydrazinyl. Condensation of 11-hydrazinyl PBD with aldehydes possessing various substitutions was performed to obtain (S,E)-11-[2-(arylmethylene) hydrazono] pyrrolo [2,1-c] [1,4] b
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21

Wilkinson, Gary P. "Pharmacological characterisation of selected pyrrolobenzodiazepines as anti-cancer agents. Pharmacokinetic and pharmacodynamic characterisation of the pyrrolobenzodiazepine dimer SJG-136 and the monomers D709119, MMY-SJG and SJG-303." Thesis, University of Bradford, 2004. http://hdl.handle.net/10454/12542.

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This study aimed to investigate the pharmacology of selected pyrrolobenzodiazepine (PBD) compounds shown to have cytotoxic activity with predicted DNA sequence selectivity. Research focused upon the PBD dimer, SJG-136, selected for clinical trials, and the novel PBD monomer compounds D709119, MMY-SJG and SJG-303. SJG-136, a novel sequence-selective DNA minor groove cross-linking agent, was shown to have potent tumour cell type selective cytotoxicity in in vitro assays. Pharmacokinetic studies in mice via both the i.p. and i.v. route (dosed at the maximum tolerated dose (MTD)) showed that SJ
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22

Magnusson, Wilhelm. "The EU General Data Protection Regulations and their consequences on computer system design." Thesis, KTH, Skolan för datavetenskap och kommunikation (CSC), 2017. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-213025.

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As of writing this thesis, the EU’s new data protection laws (GDPR) will start to apply within one year. The new regulations are poorly understood by many and rumours of varying accuracy are circling the IT industry. This thesis takes a look at the parts of the GDPR concerning system design and architecture, clarifying what they mean and their consequences for system design. The new regulations are compared to the old data protection laws (Directive 95/46/EC), showing how companies must alter their computer systems in order to adapt. Using evaluations of the old data protection laws prediction
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23

Wilkinson, Gary Paul. "Pharmacological characterisation of selected pyrrolobenzodiazepines as anti-cancer agents : pharmacokinetic and pharmacodynamic characterisation of the pyrrolobenzodiazepine dimer SJG-136 and the monomers D709119, MMY-SJG and SJG-303." Thesis, University of Bradford, 2004. http://hdl.handle.net/10454/12542.

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This study aimed to investigate the pharmacology of selected pyrrolobenzodiazepine (PBD) compounds shown to have cytotoxic activity with predicted DNA sequence selectivity. Research focused upon the PBD dimer, SJG-136, selected for clinical trials, and the novel PBD monomer compounds D709119, MMY-SJG and SJG-303. SJG-136, a novel sequence-selective DNA minor groove cross-linking agent, was shown to have potent tumour cell type selective cytotoxicity in in vitro assays. Pharmacokinetic studies in mice via both the i.p. and i.v. route (dosed at the maximum tolerated dose (MTD)) showed that SJG-1
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24

Söderström, Gunilla. "On the combustion and photolytic degradation products of some brominated flame retardants." Doctoral thesis, Umeå University, Chemistry, 2003. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-107.

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<p>Many modern products, especially electronic goods, are protected by brominated flame retardants (BFR). Some of the most common flame retardants are polybrominated diphenylethers (PBDE), tetrabromobisphenol-A (TBBP-A) and hexabromocyclododecane (HBCD). These compounds have been found in environmental samples and shown to have physiological effects on experimental animals. This thesis considers end-of-life aspects of brominated flame retardants. When spread in the environment, these compounds may be degraded into other forms. For example, if sludge contaminated with PBDE is used as an agricul
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25

Ellis, Cameron B. "Tribopairs in Wellbore Drilling: A Study of PCD Tilting Pad Bearings in an Electric Submersible Pump." BYU ScholarsArchive, 2017. https://scholarsarchive.byu.edu/etd/7233.

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A polycrystalline diamond was tested as a bearing material for a tilting pad thrust bearing to be used in an electric submersible pump, which elevates process fluids from the bottom of well bores. The goal of this study was to compare the PCD to a current best of technology, which is stainless steel with an engineering polymer.This study found that PCD can handle larger loads than current technology but is limited in size due to diamond sintering and manufacturing constraints. The maximum size is Ø75mm.
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26

Renner, Annelies. "Mise au point de tests "preuve de principe" pour l'étude des inhibiteurs de la Plk1 et caractérisation de la Plk1 en tant que cible dans le traitement des leucémies aigües myéloïdes." Toulouse 3, 2008. http://thesesups.ups-tlse.fr/430/.

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La Polo-like kinase1 (Plk1) est un régulateur mitotique majeur, surexprimé dans différents cancers et souvent associé à un mauvais pronostic. D'un point de vue expérimental, l'expression constitutive de la Plk1 dans des cellules NIH 3T3 entraîne leur transformation et leurs confère la capacité à former des tumeurs chez des souris athymiques. De plus, la déplétion de Plk1 dans des cellules cancéreuses induit souvent leur apoptose. Plk1 est donc une cible potentielle très étudiée dans le cadre des thérapies anti-cancéreuses. L'un des objectifs de ma thèse a été de générer des outils moléculaires
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27

Gonzalez, Walter G. "Protein-Ligand Interactions and Allosteric Regulation of Activity in DREAM Protein." FIU Digital Commons, 2016. http://digitalcommons.fiu.edu/etd/2503.

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Downstream regulatory antagonist modulator (DREAM) is a calcium sensing protein that co-assembles with KV4 potassium channels to regulate ion currents as well as with DNA in the nucleus, where it regulates gene expression. The interaction of DREAM with A-type KV4 channels and DNA has been shown to regulate neuronal signaling, pain sensing, and memory retention. The role of DREAM in modulation of pain, onset of Alzheimer’s disease, and cardiac pacemaking has set this protein as a novel therapeutic target. Moreover, previous results have shown a Ca2+ dependent interaction between DREAM and KV4/D
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28

Löfstrand, Karin. "Trends and exposure of naturally produced brominated substances in Baltic biota - with focus on OH-PBDEs, MeO-PBDEs and PBDDs." Doctoral thesis, Stockholms universitet, Institutionen för material- och miljökemi (MMK), 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:su:diva-54421.

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The semi-enclosed and brackish Baltic Sea has become heavily polluted by nutrients, anthropogenic organic and inorganic chemicals via human activities. Persistent organic pollutants (POPs) have been thoroughly investigated due to their linkage to toxic effects observed in Baltic biota. There has been far less focus on semi-persistent pollutants e.g. naturally produced oraganohalogen compounds (NOCs) and their disturbances in the environment. This thesis is aimed on assessment of levels and trends of naturally produced brominated compounds in Baltic biota; more specifically on hydroxylated poly
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29

Andersson, Carl, and John Pettersson. "Behovet av ökad kontroll i stålbyggnadskonstruktioner." Thesis, Linnéuniversitetet, Institutionen för byggteknik (BY), 2019. http://urn.kb.se/resolve?urn=urn:nbn:se:lnu:diva-85778.

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I arbetet undersöks behovet av ökad kontroll i stålbyggnadskonstruktioner med avseende på utförandefel. Riksdagen beslutade 1 juni 1994 att förändra Plan- och bygglagen (PBL) där förändringen trädde i kraft 1995 och bland annat innebar att hela ansvaret för en byggnads uppförande och kontroll lades på byggherren. Efter vintrarna 2009/10 och 2010/11 där flera tak rasade av snötyngden uppdagades en rad dimensionerings- och utförandefel. Under examensarbetet undersöktes vad som händer med säkerheten i byggnadskonstruktioner i stål som genomgår förändringar under dess livslängd och en jämförelse m
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30

Khan, Simeen. "Colloidal PbS and PbS/CdS Core/Shell Nanosheets." Bowling Green State University / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=bgsu1447955111.

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31

Flayhan, Ali. "Reconnaissance phage-bactérie dans le système phage T5 - E. Coli : Caractérisation biochimique et structurale du complexe FhuA-pb5 et de la protéine caudale pb9." Paris 7, 2012. http://www.theses.fr/2012PA077164.

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Au cours de cette thèse, j'ai abordé la première étape de l'infection dans le système E. Coli -phage T5. Mes travaux se sont focalisés sur la caractérisation du complexe formé entre pb5, la protéine de liaison au récepteur (RBP) de T5 et son récepteur FhuA à la surface d'E. Coli. J'ai montré que le complexe est très stable et identifié le domaine «bouchon» de FhuA comme un nouveau site d'interaction de pb5. La formation du complexe n'induit pas de réarrangements des structures de pb5 et/ou de FhuA. Seuls des changements de conformation subtils lors de la formation du complexe, au niveau de str
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32

Price, Jamie H., Aimee Govett, Misty Davis, Robyn Ivester, Teresa Howard, and Lisa Messimer. "PBL Meets PBL: Project-Based Learning Meets Planet-Based Learning." Digital Commons @ East Tennessee State University, 2019. https://dc.etsu.edu/etsu-works/6025.

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Project-based learning (PBL) is centred on a challenging, yet meaningful, driving question and culminates in a product that students create or do to showcase their learning to a public audience. Other essential elements of a true PBL experience include: sustained inquiry, authentic tasks, opportunities for students to make decisions about their culminating product, reflection, critique, and revision (Hallermann, Larmer, & Mergendoller, 2011). A well-designed PBL combines curriculum and instructional activities to cultivate 21st century skills in students to prepare them for future success in t
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Sepúlveda, Valenzuela Gabriel Ignacio. "Evaluación de la diversidad genética de los genes PB2, PB1 y PA del complejo polimerasa del virus influenza tipo A de origen porcino en Chile." Tesis, Universidad de Chile, 2018. http://repositorio.uchile.cl/handle/2250/171772.

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Memoria para optar al Título Profesional de Médico Veterinario<br>El virus influenza A (FLUAV) ha sido ampliamente estudiado debido a su gran importancia en salud pública y animal. Una de las razones de esto es su gran variabilidad genética otorgada en gran medida por el proceso de reassorment o reordenamiento genético. Este estudio consistió en la determinación de la diversidad genética de los genes que componen el complejo polimerasa del virus, es decir, los genes que codifican para la polimerasa básica 2 (PB2), la polimerasa básica 1 (PB1) y la polimerasa ácida (PA) de virus aislados de pla
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Friedman, Sandra de Castro. "Arcabouço teórico para discussões sobre o panorama multifacetado da privacidade na era digital." Universidade Federal de Pernambuco, 2013. https://repositorio.ufpe.br/handle/123456789/12371.

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Submitted by Luiz Felipe Barbosa (luiz.fbabreu2@ufpe.br) on 2015-03-12T15:12:38Z No. of bitstreams: 2 Dissertaçao Sandra Friedman.pdf: 3093791 bytes, checksum: a8717835d5925a6a173e5d53ca7694bb (MD5) license_rdf: 1232 bytes, checksum: 66e71c371cc565284e70f40736c94386 (MD5)<br>Approved for entry into archive by Daniella Sodre (daniella.sodre@ufpe.br) on 2015-03-13T12:59:12Z (GMT) No. of bitstreams: 2 Dissertaçao Sandra Friedman.pdf: 3093791 bytes, checksum: a8717835d5925a6a173e5d53ca7694bb (MD5) license_rdf: 1232 bytes, checksum: 66e71c371cc565284e70f40736c94386 (MD5)<br>Made available in DSpace
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Lind, Herta. "Meningsfullt lärande med PBL?" Thesis, Linköping University, Department of Educational Science (IUV), 2001. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-888.

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<p>Arbetet handlar om huruvida man kan få till ett meningsfullt lärande genom att använda sig av metoden PBL, problembaserat lärande, i grundskolan. Jag gör en kort presentation av lärande under 1900-talet för att därefter koncentrera mig på tre pedagoger, Marton, Säljö och Dewey. Utifrån dessa tre pedagogers syn på lärande undersöker jag PBL. Jag beskriver hur metoden PBL fungerar och hur den är uppbyggd. Mycket i PBL överensstämmer med vad Marton, Säljö och Dewey anser vara ett lärande som ger bra resultat. Som motvikt har jag tagitmed Inger Enkvist som står för en helt annan syn på hur skol
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Andersen, Alexander. "Regional fysisk planering - I vägvalet om att planera enligt PBL eller utanför PBL." Thesis, Blekinge Tekniska Högskola, Institutionen för fysisk planering, 2021. http://urn.kb.se/resolve?urn=urn:nbn:se:bth-22107.

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Denna uppsats avser att undersöka hur olika institutioner på olika politiska och geografiska nivåer förhåller sig till och tillämpar lagändringen gällande den regionala fysiska planeringen som kom år 2019. Uppsatsen utgår från två frågeställningar: Hur tolkas lagändringen och hur ser argumentationen ut kring en regional fysisk planering enligt plan- och bygglagen (PBL) och utanför PBL samt vilka konsekvenser en lagstadgad regional fysisk planering enligt PBL kan få för kommunerna, kommunalförbunden och regionerna.  För att studera detta har jag valt att använda mig av en fallstudie. Fallet som
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37

Cuba, B. Elmer. "Estimación del PBI potencial y de la brecha del PBI: Perú 1970-1995." Economía, 2012. http://repositorio.pucp.edu.pe/index/handle/123456789/117258.

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Harris, Joel Mark. "Static characteristics and rotordynamic coefficients of a four-pad tilting-pad journal bearing with ball-in-socket pivots in load-between-pad configuration." [College Station, Tex. : Texas A&M University, 2008. http://hdl.handle.net/1969.1/ETD-TAMU-3194.

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Lantto, Joni, and Henri Lehtonen. "Medborgarinflytande i detaljprocessen : En jämförelse mellan PBL 1987 samt PBL 2010 ur ett demokratiperspektiv." Thesis, Uppsala universitet, Institutionen för geovetenskaper, 2011. http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-183582.

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In the year 2002 a commission wasappointed by the government and taskedto clear up possible flaws in the lawgoverning spatial planning (Plan ochbygglagen, PBL). The commission's reportlaid the foundations for a new law whichwas adopted by the Swedish parliament onthe 20th of June 2010 and is scheduledto come into effect on the 2nd of May2011.The purpose of this thesis has been toexamine the changes made in the new law,primarily from a civil-rights point ofview, focusing on the appeal process.This is a highly interesting subjectconsidering one reason behind the newlaw was to simplify and stream
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Persson, Filip. "Med PBL i geografiundervisningens centrum." Thesis, Malmö högskola, Fakulteten för lärande och samhälle (LS), 2012. http://urn.kb.se/resolve?urn=urn:nbn:se:mau:diva-36130.

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I det här arbetet behandlas PBL och hur det fungerar som arbetssätt i geografiundervisning på gymnasiet. Jag undersöker vilka positiva respektive negativa aspekter det finns med att använda PBL i verksamheten samt vad arbetssättet utifrån dess positiva sidor kan tillföra geografiundervisning på gymnasiet. För att besvara min frågeställning har jag genomfört två olika typer av semistrukturerade intervjuer. Den första var en samtalsintervju med en pedagog som har mångårig erfarenhet av PBL-baserad undervisning på gymnasiet. Den andra en fokusgruppintervju med fyra elever från en årskurs två-klas
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41

Vlk, Bronislav. "Možnosti videokonferencí v PBX Asterisk." Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2012. http://www.nusl.cz/ntk/nusl-219738.

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This thesis deals with the possibilities of video conferencing in Asterisk PBX and their use in practice. They also described the contingencies and how its configuration. Particular attention is paid to the protocols SIP, IAX and H.323, which are described in one of the chapters. The thesis was created by the Asterisk PBX, which demonstrates cooperation with videoconferencing clients. The thesis describes the configuration files so that the central set. Conclusion the work assesses the use of codecs for different clients.
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Hensley, John Eric. "Rotordynamic coefficients for a load-between-pad, flexible-pivot tilting pad bearing at high loads." Texas A&M University, 2006. http://hdl.handle.net/1969.1/4404.

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The dynamic and static performance of a flexure-pivot tilting pad bearing is presented at a load between pad configuration for various load and speed combinations. A similar work performed on the same bearing at lower loads ranging from 0-1 MPa (0-150 psi) by Al-Ghasem was tested, whereas the current work investigates effects in the load range between 1-2.2 MPa (150-320 psi). The bearing design parameters include: 4 pads with pad arc angle 72º and 50% pivot offset, pad axial length 0.0762 m (3 in), pad radial clearance 0.254 mm (0.010 in), bearing radial clearance 190.5 µm (0.0075 in), p
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Ito, Edson Noriyuki. "Estudos microrreológicos da blenda PBT/SAN." Universidade Federal de São Carlos, 2006. https://repositorio.ufscar.br/handle/ufscar/647.

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Made available in DSpace on 2016-06-02T19:09:58Z (GMT). No. of bitstreams: 1 TeseENI.pdf: 5287790 bytes, checksum: c30a5b5cc0b140789ff3816da6250c1e (MD5) Previous issue date: 2006-09-22<br>Financiadora de Estudos e Projetos<br>This work was motivated by the need of a better understanding of the microrheological characteristics of polybutylene terephthalate, PBT, polymer blends, such as the matrix phase PBT and the styrene-acrylonitrile, SAN copolymer as dispersed phase. The main purpose of the microrheological studies carried out was to analyze the rheological behavior and the morphology, as
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Sestak, Mark R. Carleton University Dissertation Computer Science. "Traffic flow monitoring in PBX networks." Ottawa, 1990.

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45

Děcký, Miroslav. "Referenční návrh HID periferie Touch Pad." Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2018. http://www.nusl.cz/ntk/nusl-377103.

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This master’s thesis deals with the draft and design of HID periphery Touchpad. The Kinetis microcontroller produced by NXP, TSI periphery and embedded library NXP Touch are used for the design. The resulting device is connected as USB HID type mouse or trackpad. Hardware part of the project is implemented by whole MCU Kinetis Family on PCBs designed by author, one part also uses evaluation kits NXP Freedom KL25z and KE15z.
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Šalko, Jaroslav. "Implementace WebRTC v Open source PBX." Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2018. http://www.nusl.cz/ntk/nusl-377319.

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The topic of this work is verification of support WebRTC communication through selected Open Source PBX. This work examine demands for WebRTC communications and describes configuration of branch centers for this type of communication. In the theoretical part is reader acquainted with the term WebRTC and with protocols related to this kind of communications. The purpose of this part of the work is to bring the reader closer look to the principles of functioning to ensuring support for this kind of communications. This is also connected with Description of basic interfaces of WebRTC applications
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Benýšek, Jiří. "Vazba GSM modemu na PBX Asterisk." Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2010. http://www.nusl.cz/ntk/nusl-218255.

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Short Message Service (shortly SMS) is the most widely used type of communication systems. The main advantages are that allow a fast exchange of messages between devices, a very good availability through GSM and a reasonable price. Nowadays the SMS service support has expanded to include other technologies such as a service of the information navigation and the remote connection. The master‘s thesis concentrates on the Short Message Service, deals with basic principles and statements using by this service. The topic of the thesis is software PBX Asterisk and its possibility of SMS implementati
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Orsák, David. "Zabezpečení Open source PBX proti útokům." Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2012. http://www.nusl.cz/ntk/nusl-219480.

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This master's thesis deals with open source PBX security against security attacks. In the theoretical part is detailed description of problematic about attacks that could be used on VoIP systems with high focus on the Denial of Service attack. Furthermore are in theoretical part described methods of security of initialization protocol SIP. Individual chapter is devoted to intrusion detection and prevention of IDS and IPS systems, focusing on Snort and OSSEC. In the practical part of the work was created generator of attacks against various PBX systems, which was subsequently used for detailed
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Hynek, Luboš. "Metody zajištění IP PBX proti útokům." Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2013. http://www.nusl.cz/ntk/nusl-220328.

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This master project focuses on the possibilities of protecting the most common free software PBX Asterisk, FreeSWITCH and YATE. In practice, it was verified the behavior of PBX in the attacks and suggested protection against them on one of the most popular distributions of Linux server on CentOS. Tool was created to simulate several types of attacks targeting denial of service. Both protective options PBX themselves and operating system capabilities are used in this work. Comparison was also the possibility of protection of individual PBX with each other. It also includes a brief description o
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Janeček, Václav. "Open source PBX Kamailo a OpenSIPs." Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2014. http://www.nusl.cz/ntk/nusl-220656.

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Open source PBX Kamailio and OpenSIPS diploma thesis covers familiarization with appointed SIP exchanges and with their power comparing. A detailed installation instructions on the operating system Ubuntu is the aim of this work too. The work includes the historical development of telephone exchanges with a focus on the latest generation. The following is SIP protocol basic description and components that can be composed SIP exchanges. Another part is devoted to the development of exchanges Kamailio and OpenSIPS. The thesis contain the archutecture and configuration file description. The pract
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