Relevant bibliographies by topics / Patient compliance

Academic literature on the topic 'Patient compliance'

Author: Grafiati
Published: 4 June 2021
Last updated: 30 July 2024

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Journal articles on the topic "Patient compliance"

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Kolton, Kathryn Ann, and Paula Piccolo. "Patient Compliance." Nurse Practitioner 13, no. 12 (December 1988): 37???51. http://dx.doi.org/10.1097/00006205-198812000-00006.

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Petchey, R., and E. Murphy. "Patient compliance." BMJ 305, no. 6866 (December 5, 1992): 1434. http://dx.doi.org/10.1136/bmj.305.6866.1434.

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Appleton, R. E. "Patient compliance." BMJ 305, no. 6866 (December 5, 1992): 1434. http://dx.doi.org/10.1136/bmj.305.6866.1434-a.

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Meredith, P. A. "Patient compliance." BMJ 305, no. 6866 (December 5, 1992): 1434. http://dx.doi.org/10.1136/bmj.305.6866.1434-b.

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Allard, S. "Patient compliance." BMJ 305, no. 6866 (December 5, 1992): 1434–35. http://dx.doi.org/10.1136/bmj.305.6866.1434-c.

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Åberg, Hans. "Patient Compliance." Acta Medica Scandinavica 202, S606 (April 24, 2009): 25–31. http://dx.doi.org/10.1111/j.0954-6820.1977.tb18025.x.

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Mizon, Jennifer A. "Patient Compliance." Physiotherapy 76, no. 8 (August 1990): 457. http://dx.doi.org/10.1016/s0031-9406(10)62979-3.

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Mizon, Jennifer A. "Patient Compliance." Physiotherapy 76, no. 12 (December 1990): 758. http://dx.doi.org/10.1016/s0031-9406(10)63151-3.

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Mohiuddin, AK. "Patient-Provider Relationship: Compliance with Care." International Journal of Research and Development in Pharmacy & Life Sciences 7, no. 6 (November 2018): 3138–49. http://dx.doi.org/10.21276/ijrdpl.2278-0238.2018.7(6).3138-3149.

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Dahiya, Dr Parveen, Dr Reet Kamal, Dr Mukesh Kumar, and Dr Rohit Bhardwaj. "PATIENT COMPLIANCE - KEY TO SUCCESSFUL DENTAL TREATMENT." Asian Pacific Journal of Health Sciences 1, no. 1 (January 2014): 39–41. http://dx.doi.org/10.21276/apjhs.2014.1.1.6.

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Dissertations / Theses on the topic "Patient compliance"

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Ramones, Valerie. "Patient education and compliance in the hypertensive elderly." Thesis, The University of Arizona, 1988. http://hdl.handle.net/10150/276814.

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This study examined the difference among 3 patient education intervention strategies and compliance in the hypertensive elderly. The strategies were verbal instructions, written instructions and both verbal and written instructions. An ex post facto descriptive design was implemented based on a Cognitive Information Processing Theory of Learning. Forty subjects were recruited and interviewed. Data analysis revealed that compliance did not differ significantly with the type of educational strategy.
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Cochrane, Lorna June. "Redefining compliance education." Thesis, McGill University, 2003. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=84496.

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Calls for innovations and research echo in the latest reviews and meta-analyses of methods to enhance compliance (Haynes, McDonald, Garg, & Montague, 2003; Pekkala & Merinder, 2002; Peterson, Takiya, & Finley, 2003). In spite of effective therapy emerging daily from medical research, non-compliance appears at disappointing rates. Over the past 25 years, the gap is widening between what we could achieve with available and emerging health care and what we are currently achieving. This lack of compliance with proven therapy thwarts health outcomes and adds to the growing health care costs. In Canada, direct and indirect costs resulting from non-compliance with therapies amount to 7 to 9 billion dollars per year (Coambes, Jensen, Hao Her, Ferguson, Jarry, Wong, & Abrahamsohn, 1995; Coambs, 1997; Tamblyn & Perreault., 1997).
Many stakeholders play a role in the complex compliance equation. The physician plays a key role. Supporting physician maintenance of competence are continuing health educators. Together, the physicians and educators seek to employ the latest evidence in their practices to enhance compliance. Explicating the thinking that guides their medical and educational practices helps researchers and educators to understand problems in current approaches to compliance.
It is argued that prior knowledge is the basis for learning (Limon & Mason, 2002). Understanding current knowledge and behavior of a learner establishes the baseline to build effective educational activities that will impact targeted outcomes. Further, education designed by using learner's prior knowledge is the scaffold for future learning (Alexander, 1996).
This survey research examines the thinking and behavior of a randomized sample of Canadian physicians and networking sample of educators. Quantitative and qualitative analysis of participant thinking and interventions reveal different perspectives and mental models that guide their clinical and educational decisions. The findings reveal important differences with current clinical recommendations. The study identifies important variables that explain the differences and lack of progress in this area.
Directions for future education and research are forwarded. The recommendations, based in theories of change and cognition, offer important insights and opportunities to make advances toward enhancing current rates of compliance.
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Roberts, Eric Eldon. "Patient compliance and non compliance in orthodontic treatment." Thesis, University of Nottingham, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.328955.

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Morrical, Kathy Jo S. "Readiness to learn as described by adults experiencing a change in health/illness status." Virtual Press, 2003. http://liblink.bsu.edu/uhtbin/catkey/1272425.

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Peng, Siwei, and 彭思玮. "Medication nonadherence among hypertension patients." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2012. http://hub.hku.hk/bib/B48425230.

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Optimal effect of medical treatment requires patients' adherence to those treatments, which plays a even greater role than the medical decision made by physicians. With the epidemiological dynamic evolving, chronic disease becomes the major burden of healthcare, such as AIDS, hypertension, COPD, tuberculosis, asthma, epilepsy, schizophrenia, depression and diabetes, which make the adherence especially medication adherence a sightworthy issue because the risk of poor adherence with the complexity and duration of treatment with both of them are inherent to chronic diseases. Among patients with hypertension, medication nonadherence contributes to poorly controlled blood pressure as an significant yet unrecognized role. With the mediator of negative outcomes of further development of vascular disorders, including stroke, heart failure, renal insufficiency and coronary diseases, medication nonadherence to antihypertensives become the root of all devil in terms of healthcare. In terms of healthcare utilization, it costs approximately 396 to 792 million dollars per year and creates a significant burden. Effect factors for medication nonadherence among hypertension patients include knowledge about hypertension, beliefs about hypertension, perceived beliefs about medication, inadequate self-management behaviors, physician-patient relationship, social support and healthcare policy. The achievements of current single level interventions are not satisfactory, therefore multiple level interventions are calling for attention.Everyone in the healthcare system are responsible to alter the situation. A comprehensive healthcare system that consummates all the effect factors is the effective and efficient solution.
published_or_final_version
Public Health
Master
Master of Public Health
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Heinemann, Stefan. "Data power to the patients! Patient-driven data business, not data-driven patient business: the centrality of the patient in the commerce of digital healthcare." Universität Leipzig, 2018. https://ul.qucosa.de/id/qucosa%3A32044.

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Data-driven business models make up the medical and healthcare market in large parts, a trend reinforced by further technological developments and regulation. Care must be taken to avoid a situation where only a few players benefit. It’s weird the patient has to become a customer in order to be a human being in the health business: The consistent empowerment of patients to handle their own data is essential.
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Tumelo, Sylvia Mmamoseka 1953. "COMPLIANCE AND FAMILY INVOLVEMENT WITH TUBERCULOSIS PATIENTS IN BOTSWANA." Thesis, The University of Arizona, 1986. http://hdl.handle.net/10150/275566.

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Useman, Tammy. "Patient Compliance and Recovery Outcomes in Rehabilitation Therapy." Honors in the Major Thesis, University of Central Florida, 2006. http://digital.library.ucf.edu/cdm/ref/collection/ETH/id/1007.

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This item is only available in print in the UCF Libraries. If this is your Honors Thesis, you can help us make it available online for use by researchers around the world by following the instructions on the distribution consent form at http://library.ucf.edu/Systems/DigitalInitiatives/DigitalCollections/InternetDistributionConsentAgreementForm.pdf You may also contact the project coordinator, Kerri Bottorff, at kerri.bottorff@ucf.edu for more information.
Bachelors
Health and Public Affairs
Health Sciences
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Carpenter, Roger D. "Cognitive appraisal of perceived threat of diabetes and adherence to self-management behaviors." Morgantown, W. Va. : [West Virginia University Libraries], 2008. https://eidr.wvu.edu/etd/documentdata.eTD?documentid=5813.

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Thesis (Ph. D.)--West Virginia University, 2008.
Title from document title page. Document formatted into pages; contains v, 113 p. : ill. Includes abstract. Includes bibliographical references (p. 96-113).
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Harwood, Susan Elizabeth. "Medication compliance in out-patient clinical trials." Thesis, University of Sunderland, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.330315.

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Books on the topic "Patient compliance"

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Bosworth, Hayden B. Improving patient treatment adherence: A clinician's guide. New York: Springer, 2010.

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Vincent, Karen. Is there a link between patient perception and patient compliance in injured sports patients? Northampon: Nene College, 1993.

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Bosworth, Hayden B. Patient treatment adherence: Concepts, interventions, and measurement. Mahwah, NJ: Lawrence Erlbaum Associates, Publishers, 2006.

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E, Moyers Robert, McNamara James A, Trotman Carroll-Ann, and University of Michigan. Center for Human Growth and Development., eds. Creating the compliant patient. Ann Arbor, Mich: Center for Human Growth and Development, University of Michigan, 1996.

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Ono, Hiromi. Gender, status, role, and adherence: Implications for social structure on patient adherence to medical recommendations. Santa Monica, CA (1700 Main St., P.O. Box 2138, Santa Monica 90407-2138): RAND, 1992.

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Ono, Hiromi. Gender, status, role, and adherence: Implications for social structure on patient adherence to medical recommendations. Santa Monica, CA: Rand, 1992.

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Bosworth, Hayden B. Improving patient treatment adherence: A clinician's guide. New York: Springer, 2010.

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Fainzang, Sylvie. Médicaments et société: Le patient, le médecin et l'ordonnance. Paris: Presses Universitaires de France, 2001.

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Hughes, Angela. A theophylline compliance study. Ottawa: Ottawa Civic Hospital, 1990.

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H, Bigelow J., ed. Patient compliance with and attitudes towards Health Buddy. Santa Monica, CA: RAND Health, 2000.

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Book chapters on the topic "Patient compliance"

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Dunbar, Jacqueline, and Louise Waszak. "Patient Compliance." In Applied Clinical Psychology, 365–82. Boston, MA: Springer US, 1990. http://dx.doi.org/10.1007/978-1-4613-0505-7_23.

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Riolo, Stephanie A., and Christina G. Weston. "Patient Compliance." In Psychiatry, 2447–61. Chichester, UK: John Wiley & Sons, Ltd, 2008. http://dx.doi.org/10.1002/9780470515167.ch114.

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Baum, Neil, Marc J. Kahn, and Jeffery Daigrepont. "Patient Medication Compliance." In The Business of Building and Managing a Healthcare Practice, 185–90. Cham: Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-031-37623-8_27.

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Moldenhauer, Kendra L., and Peggy Alder. "Compliance to Patient Safety Culture." In Patient Safety in Surgery, 151–73. London: Springer London, 2014. http://dx.doi.org/10.1007/978-1-4471-4369-7_13.

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Eldo, Frezza. "Non-Compliance and Patient Termination." In Medical Ethics, 97–102. Boca Raton : Taylor & Francis, 2019.: Productivity Press, 2018. http://dx.doi.org/10.4324/9780429506949-13.

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Huggins, Richard H., Jackie Gardner, and Amit G. Pandya. "Patient Support, Education, and Compliance." In Vitiligo, 69–75. Chichester, UK: John Wiley & Sons, Ltd, 2018. http://dx.doi.org/10.1002/9781118937303.ch9.

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Schuller, Susanne. "Die Beziehungen zwischen Arzt, Patient und Krankenversicherung." In Steigerung der Patienten-Compliance, 46–59. Wiesbaden: Deutscher Universitätsverlag, 2002. http://dx.doi.org/10.1007/978-3-663-08973-5_4.

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Métry, Jean-Michel. "Patient Compliance: Pharmionics, A New Discipline." In Principles and Practice of Pharmaceutical Medicine, 379–87. Oxford, UK: Wiley-Blackwell, 2010. http://dx.doi.org/10.1002/9781444325263.ch30.

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Viskoper, J. R. "Patient Compliance with Health Behavior Programs." In Manual of Nonpharmacological Control of Hypertension, 24–27. Berlin, Heidelberg: Springer Berlin Heidelberg, 1990. http://dx.doi.org/10.1007/978-3-642-74720-5_4.

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Meise, U., and V. Günther. "Compliance — Ein Aspekt der Arzt-Patient-Beziehung." In Schriftenreihe der Wissenschaftlichen Landesakademie für Niederösterreich, 37–46. Vienna: Springer Vienna, 1991. http://dx.doi.org/10.1007/978-3-7091-3371-2_4.

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Conference papers on the topic "Patient compliance"

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Rosati, Giulio, James E. Bobrow, and David J. Reinkensmeyer. "Compliant Control of Post-Stroke Rehabilitation Robots: Using Movement-Specific Models to Improve Controller Performance." In ASME 2008 International Mechanical Engineering Congress and Exposition. ASMEDC, 2008. http://dx.doi.org/10.1115/imece2008-68234.

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Post-stroke neurorehabilitation is an emerging application field of robotics, aiming to design new treatment systems and protocols based on the use of robotic technology and virtual reality to improve patient recovery after stroke. One goal in this field is to develop robotic therapy devices that are compliant but can still assist weakened patients in making desired movements. It is hypothesized that, in this way, the interaction with the robotic system can maintain patient engagement and effort, and promote and stimulate the motor learning process of the patient. One way that has been proposed to maintain compliance while assisting weak patients is to use an adaptive controller with a forgetting term, which allows the robotic system to learn a model of the forces needed to assist the patients during exercises while encouraging patient effort. A limitation of such an approach is that the adaptive gain must be large enough to rapidly change the model for different target movements, which decreases the compliance of the robot. We show here in simulation that by building independent models for different target movements, robot compliance can be increased while still accurately achieving the target movements.
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Lu, Xinyi, Runtong Zhang, Wen Wu, and Xiaopu Shang. "How does Health Website Influence Patient Compliance." In the 8th International Conference. New York, New York, USA: ACM Press, 2018. http://dx.doi.org/10.1145/3268891.3268894.

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Ring, J. B., and Charles Kim. "A Passive Brace to Improve Activities of Daily Living Utilizing Compliant Parallel Mechanisms." In ASME 2016 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. American Society of Mechanical Engineers, 2016. http://dx.doi.org/10.1115/detc2016-59616.

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Idiopathic scoliosis is a deformity of the spine that affects 2–3% of adolescents. The treatment of scoliosis often requires the use of a rigid brace to align the spine and prevent progression of the deformation. The most common brace, referred to as the Boston brace, has a high success rate in preventing progression of the scoliotic curve. The common root failure is lack of patient compliance in wearing the brace for the prescribed time. This lack in compliance is due to patient discomfort, both physically and emotional, and the patients’ limited ability to perform activities of daily living (ADL) when wearing the brace. The likelihood of needing surgery increases dramatically when bracing is unsuccessful. We seek to improve patients’ comfort by designing a brace that improves range of motion, while remaining stiff in the corrective direction. Primary ranges of motion were acquired using a motion capture system. A kinematic analysis was performed using homogeneous transformations and screw theory to determine primary screw axes of the motions. The required lateral stiffness for the brace was found in literature. Compliant mechanisms are used because they can apply the corrective force, but also allow the patients some range of motion. The mechanism implementation was characterized using finite element analysis and compared to a physical model test. Initial findings confirm that compliant mechanisms are suitable for the application of a scoliosis brace. We have found that the proposed brace can apply the necessary forces at reasonable displacements. The proposed brace will not allow the patient a full range of motion, but we believe that it will achieve an improved range of motion that will increase a patient’s ability to perform activities of daily living.
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Ghazanfar, Auns, Kristel Longman, Reny Mathai, William Heslop-Harrison, and Sarah Arunakumar. "234 Cardiac rehabilitation compliance, are we meeting guidelines?" In British Cardiovascular Society Annual Conference, ‘Back to the patient’, 3–5 June 2024. BMJ Publishing Group Ltd and British Cardiovascular Society, 2024. http://dx.doi.org/10.1136/heartjnl-2024-bcs.226.

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Görgülü, B., R. C. Kardaş, D. Koç Şeramet, R. Mercan, M. E. Tezcan, H. Küçük, B. Göker, and M. A. Öztürk. "AB0127 EVALUATION OF TREATMENT COMPLIANCE IN GOUT PATIENTS: A PATIENT-CENTERED STUDY." In EULAR 2024 European Congress of Rheumatology, 12-15 June. Vienna, Austria. BMJ Publishing Group Ltd and European League Against Rheumatism, 2024. http://dx.doi.org/10.1136/annrheumdis-2024-eular.6153.

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Hainagiu, Simona magdalena. "IMPROVING SELF-EFFICIENCY AND TREATMENT COMPLIANCE OF DIALYZED PATIENTS - AN INTERVENTION TRAINING PROGRAME PROPOSAL." In eLSE 2016. Carol I National Defence University Publishing House, 2016. http://dx.doi.org/10.12753/2066-026x-16-176.

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"Improving self - efficiency and treatment compliance of dialyzed patients - an intervention training programe proposal" Abstract Chronic renal disease is one o the most invalidating disease producing major changes in patients life. Furthermore, it challenges the pa?ient to adapt to a new and fully restrictive regim marked by significant loss in the usual diet, drinking habits, social, sexual and professional behaviours. The treatment by itself forces the patient to cope with a new daily programe and medicine intake. Considering all these major and sudden changes, the patient compliance is one of the most important concern of the care team. Our study aims to describe the conditions influencing patients compliance and to propose an intervention training programe aiming to raise the compliance. Considering the self - efficiency as the mechanism that influences levels of compliance, we have analised statistically significant relationships using Pearson-2 tailed correlation. Considering the self - efficiency as the mechanism that influences levels of compliance, we have analised statistically significant relationships using Pearson-2 tailed correlation. Our results can prove that for the whole group a greater level of sel-efficiency induces a greater level of compliance. Our approch presumes that self - efficiency can be controled and enhaced by a variety of behavioral marks. The new technological resources as smartphone applications can be seen as the suport of enabling these patients category to take control of their life and to have a greater level of treatment compliance. Keywords: education, renal disease, dialysis, compliance, self - efficiency, treatment compliance
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Joymangul, Jensen Selwyn, Aicha Sekhari, Nejib Moalla, and Olivier Grasset. "Obstructive Sleep Apnea Compliance: Modeling Home Care Patient Profiles." In 2020 IEEE 33rd International Symposium on Computer-Based Medical Systems (CBMS). IEEE, 2020. http://dx.doi.org/10.1109/cbms49503.2020.00082.

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Ciliberti, Rosella, Alessandro Bonsignore, Liliana Lorettu, Maurizio Secchi, Michele Minuto, Pierluigi Santi, and Ilaria Baldelli. "Physician/patient relationship following hospital discharge – new methods of therapeutic and care continuity." In the 8th International Workshop on Innovative Simulation for Healthcare. CAL-TEK srl, 2019. http://dx.doi.org/10.46354/i3m.2019.iwish.013.

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"Healthcare organization aims to shorten hospitalization times, both to facilitate patient turnover and to avoid the risks of the nosocomial environment. Between March and September 2018, patients that were discharged after hospitalization for scheduled reconstructive breast surgery were given a portable device with the Dr. Link app installed, created to allow real-time communication with physicians. Patients and physicians completed a satisfaction survey on their experience with the use of the device. Analysis shows overall patient satisfaction in terms of improvement in relationships and quality of life. Physicians reported more responsible patient behaviour, better compliance, and earlier treatment of complications. Continuous interactive assistance can improve the discharged patient’s quality of life and therapeutic path. However, the device risks becoming a negative tool if the health care professional has not made the proper initial emotional investment in the relationship, delegating the totality of the therapeutic relationship to the tablet."
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Bozan, Karoly. "Can Information Availability Increase Patient Compliance? Mitigating Uncertainty Perceptions in the Provider-Patient Relationship." In Hawaii International Conference on System Sciences. Hawaii International Conference on System Sciences, 2017. http://dx.doi.org/10.24251/hicss.2017.406.

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Khomova, Natalya, Fatima Tashpulatova, and Sanjar Sultanov. "Compliance - is patient adherence to treatment, as well as partnerships between doctor and patient." In ERS International Congress 2017 abstracts. European Respiratory Society, 2017. http://dx.doi.org/10.1183/1393003.congress-2017.pa2702.

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Reports on the topic "Patient compliance"

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Jackson, Peyton, Brandon Crocker, and Margaret Harvey. Patient Compliance with Colorectal Cancer Screening: A Scoping Review. University of Tennessee Health Science Center, April 2023. http://dx.doi.org/10.21007/con.dnp.2023.0056.

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Ellickson, Paul, Scott Stern, and Manuel Trajtenberg. Patient Welfare and Patient Compliance: An Empirical Framework for Measuring the Benefits from Pharmaceutical Innovation. Cambridge, MA: National Bureau of Economic Research, January 1999. http://dx.doi.org/10.3386/w6890.

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Peñaloza, Blanca. Do external inspections of compliance with standards improve quality of care in healthcare organisations? SUPPORT, 2016. http://dx.doi.org/10.30846/161111.

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External inspection systems are used in healthcare to improve adherence to quality standards. They are intended to promote changes in organizational structures or processes, in healthcare provider behavior and consequently in patient outcomes.
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Yu, Mingkun, Changhao Liang, Qian He, Kexin Liu, Yuting Feng, Qianyun Chai, Jianping Liu, and Yutong Fei. The Process factors and improvement strategies of patient compliance and retention in clinical trials: a synthesis of qualitative research. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, February 2021. http://dx.doi.org/10.37766/inplasy2021.2.0024.

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Balaga, Dr Sai Krishna, Dr Amal PS, Dr Jayaram Jayaram, and Dr Naveen Naveen. MANAGEMENT OF INFECTIVE NON UNION OF SHAFT OF LONG BONES WITH LIMB RECONSTRUCTION SYSTEM. World Wide Journals, February 2023. http://dx.doi.org/10.36106/ijar/7305662.

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Background: Complex nonunions are difcult to manage due to the presence of infection, deformities, shortening, and multiple surgeries in the past. Ilizarov xation has traditionally been used to manage complex nonunions. The disadvantages of Ilizarov include poor patient compliance, frame inconvenience, and difcult frame construction. We studied ten long bone infective nonunions treated with the limb reconstruction system (LRS). Materials and methods : Between September 2020 and December 2022, we treated 10 cases of infective nonunion of long bone with the LRS. Patients were routinely followed up for 12 to 18 months and assessed both clinically and radiologically. Out of 10 cases we were able to achieve Results : : union in all cases. And eradication of infection in 90% of cases with no limb length discrepancy in any case. Bone results are excellent in 80% of cases and good in 20% of cases. Functional results are excellent in 80% of cases and good in 10% of cases, fair in 10% of cases. LRS is an alternati Conclusion : ve to the Ilizarov xation in their management of complex nonunion of long bones. It is less cumbersome to the patient and more surgeon and patient friendly.
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Lan, Yuanmei, Zitian Zhu, Zhenling Ma, Yuelun Zhang, and Tongxin Li. The effects of mindfulness-based interventions on depression, anxiety, sleep and treatment compliance in patient undergoing hemodialysis: a meta-analysis. Nursing School, Chinese Academy of Medical Sciences & Peking Union Medical College,Beijing,China, March 2023. http://dx.doi.org/10.37766/inplasy2023.3.0049.

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McCarthy, Sean T., Aneesa Motala, Emily Lawson, and Paul G. Shekelle. Prevention in Adults of Transmission of Infection With Multidrug-Resistant Organisms. Rapid Review. Agency for Healthcare Research and Quality (AHRQ), April 2024. http://dx.doi.org/10.23970/ahrqepc_mhs4mdro.

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Objectives. This rapid review summarizes literature for patient safety practices intended to prevent and control the transmission of multidrug-resistant organisms (MDROs). Methods. We followed rapid review processes of the Agency for Healthcare Research and Quality Evidence-based Practice Center Program. We searched PubMed to identify eligible systematic reviews from 2011 to May 2023 and primary studies published from 2011 to May 2023, supplemented by targeted gray literature searches. We included literature that addressed patient safety practices intending to prevent or control transmission of MDROs which were implemented in hospitals and nursing homes and that included clinical outcomes of infection or colonization with MDROs as well as unintended consequences such as mental health effects and noninfectious adverse healthcare-associated outcomes. The protocol for the review has been registered in PROSPERO (CRD42023444973). Findings. Our search retrieved 714 citations, of which 42 articles were eligible for review. Systematic reviews, which were primarily of observational studies, included a wide variety of infection prevention and control (IPC) practices, including universal gloving, contact isolation precautions, adverse effects of patient isolation, patient and/or staff cohorting, room decontamination, patient decolonization, IPC practices specifically in nursing homes, features of organizational culture to facilitate implementation of IPC practices and the role of dedicated IPC staff. While systematic reviews were of good or fair quality, strength of evidence for the conclusions was always low or very low, due to reliance on observational studies. Decolonization strategies showed some benefit in certain populations, such as nursing home patients and patients discharging from acute care hospitalization. Universal gloving showed a small benefit in the intensive care unit. Contact isolation targeting patients colonized or infected with MDROs showed mixed effects in the literature and may be associated with mental health and noninfectious (e.g., falls and pressure ulcers) adverse effects when compared with standard precautions, though based on before/after studies in which such precautions were ceased. There was no significant evidence of benefit for patient cohorting (except possibly in outbreak settings), automated room decontamination or cleaning feedback protocols, and IPC practices in long-term settings. Infection rates may be improved when IPC practices are implemented in the context of certain logistical and staffing characteristics including a supportive organizational culture, though again strength of evidence was low. Dedicated infection prevention staff likely improve compliance with other patient safety practices, though there is little evidence of their downstream impact on rates of infection. Conclusions. Selected infection prevention and control interventions had mixed evidence for reducing healthcare-associated infection and colonization by multidrug resistant organisms. Where these practices did show benefit, they often had evidence that applied only to certain subpopulations (such as intensive care unit patients), though overall strength of evidence was low.
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O'Donnell, Kevin, and Anne Greene. A Risk Management Solution Designed to Facilitate Risk-Based Qualification, Validation, and Change Control Activities within GMP and Pharmaceutical Regulatory Compliance Environments in the EU—Part II. Institute of Validation Technology, July 2006. http://dx.doi.org/10.1080/21506590.wp7142006agko-rmsdii.

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highlight the need for patient-focused and value-adding qualification, validation, and change control programmes for manufacturing and regulating medicinal products in the EU, which are cost-effective and in-line with current regulatory requirements and guidance. To this end, a formal risk management solution was presented that seeks to demonstrate, in a practical way, how Regulators and Industry in the EU may achieve these goals. This solution represents a formal and rigorous approach to risk management, offering a scientific and practical means for determining and managing, on a risk basis, the scope and extent of qualification and validation, and the likely impact of changes. Based on a ten-step, systematic process, this approach offers a ready-to-use and documented risk management methodology for these activities. This tool is not intended for use in all situations, or to address all risk areas or concerns encountered in GMP and Regulatory Compliance environments. Rather, its use should be commensurate with the complexity and/or criticality of the issue to be addressed, and in many instances, and in-line with ICH Q9 principles, a more informal approach to risk management may be more useful, and indeed proportionate.
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Huang, Houqiang, Min Huang, Qi Chen, Mark Hayter, and Roger Hayter. Health-related Serious Games on the Rehabilitation for Patients with COPD: Systematic Review Protocol. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, December 2022. http://dx.doi.org/10.37766/inplasy2022.12.0062.

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Review question / Objective: The aim of this systematic review is to identify effectiveness and patients’ demand on serious games for COPD patients as well as to recognize potential research gaps in this area by synthesizing and appraising studies examining effects of serious games on COPD patients. Eligibility criteria: OutcomesThe outcomes that include health-related endpoints such as pulmonary function, exercise capacity, dyspnea, compliance, or adverse effects, will be enrolled.Further inclusion criteriaStudies must be peer-reviewed and be in English or Chinese.Exclusion criteriaStudies will be excluded for the following reasons: (1) duplicate records;, (2) studies focused on measurement; diagnostic methods, serious game theory or game development; and (3) conference abstracts or studies that cannot find out full texts.
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FDG-PET/CT SUV for Response to Cancer Therapy, Clinically Feasible Profile. Chair Nathan Hall and Jeffrey Yap. Radiological Society of North America (RSNA) / Quantitative Imaging Biomarkers Alliance (QIBA), June 2023. http://dx.doi.org/10.1148/qiba/20230615.

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This QIBA Profile documents specifications and requirements to provide comparability and consistency for quantitative FDG-PET across scanners in oncology. It can be applied to both clinical trial use as well as individual patient management. This document organizes acquisition, reconstruction and post-processing, analysis and interpretation as steps in a pipeline that transforms data to information to knowledge. The document, developed through the efforts of the QIBA FDG-PET Biomarker Committee, has shared content with the FDG-PET UPICT protocol, as well as additional material focused on the devices used to acquire and analyze the FDG-PET data. The QIBA acquisition protocol is largely derived from the FDG-PET UPICT protocol for FDG-PET imaging in clinical trials. In the UPICT protocol, there is a carefully developed hierarchy with tiered levels of protocol compliance. This reflects the recognition that there are valid reasons to perform trials using different levels of rigor, even for the same disease/intervention combination. For example, a high level of image measurement precision may be needed in small, early-phase trials whereas a less rigorous level of precision may be acceptable in large, late-phase trials of the same drug in the same disease setting. This Profile defines the behavioral performance levels and quality control specifications for whole-body FDG-PET/CT scans used in single- and multi-center clinical trials of oncologic therapies. While the emphasis is on clinical trials, this process is also intended to apply for clinical practice. The specific claims for accuracy are detailed in the Claims section. A motivation for the development of this Profile is that while a typical PET/CT scanner measurement system (including all supporting devices) may be stable over days or weeks, this stability cannot be expected over the time that it takes to complete a clinical trial. In addition, there are well known differences between scanners and or the operation of the same type of scanner at different imaging sites. The intended audiences of this document include: Technical staff of software and device manufacturers who create products for this purpose Biopharmaceutical companies, oncologists, and clinical trial scientists designing trials with imaging endpoints Clinical research professionals Radiologists, nuclear medicine physicists, technologists, physicists and administrators at healthcare institutions (1) considering specifications for procuring new PET/CT equipment, (2) designing PET/CT acquisition protocols, (3) making quantitative measurements from PET/CT images Regulators, nuclear medicine physicians, oncologists, and others making decisions based on quantitative image measurements
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