Journal articles on the topic 'Pathway FA'
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Jenkins, Chelsea, Jenny Kan, and Maureen E. Hoatlin. "Targeting the Fanconi Anemia Pathway to Identify Tailored Anticancer Therapeutics." Anemia 2012 (2012): 1–7. http://dx.doi.org/10.1155/2012/481583.
Full textKennedy, R. D., P. Stuckert, E. Archila, M. De LaVega, C. Chen, L. Moreau, and A. D'Andrea. "Sensitivity of tumor cells deficient in the fanconi anemia pathway to inhibition of ataxia telangiectasia mutated (ATM)." Journal of Clinical Oncology 25, no. 18_suppl (June 20, 2007): 10509. http://dx.doi.org/10.1200/jco.2007.25.18_suppl.10509.
Full textLi, Niu, Jian Wang, Susan S. Wallace, Jing Chen, Jia Zhou, and Alan D. D’Andrea. "Cooperation of the NEIL3 and Fanconi anemia/BRCA pathways in interstrand crosslink repair." Nucleic Acids Research 48, no. 6 (January 25, 2020): 3014–28. http://dx.doi.org/10.1093/nar/gkaa038.
Full textHays, Laura E. "Multifunctionality of the FA pathway." Blood 121, no. 1 (January 3, 2013): 3–4. http://dx.doi.org/10.1182/blood-2012-11-464636.
Full textZhang, Haojian, David Kozono, Kevin O'Connor, Sofia Vidal-Cardenas, Abigail Hamilton, Emily Gaudiano, Joel S. Greenberger, Markus Grompe, Kalindi Parmar, and Alan D. D'Andrea. "Bone Marrow Failure in Fanconi Anemia from Hyperactive TGF-β Signaling." Blood 124, no. 21 (December 6, 2014): 356. http://dx.doi.org/10.1182/blood.v124.21.356.356.
Full textNiraj, Joshi, Anniina Färkkilä, and Alan D. D'Andrea. "The Fanconi Anemia Pathway in Cancer." Annual Review of Cancer Biology 3, no. 1 (March 4, 2019): 457–78. http://dx.doi.org/10.1146/annurev-cancerbio-030617-050422.
Full textSeton-Rogers, Sarah. "Stress management by the FA pathway." Nature Reviews Cancer 15, no. 12 (November 13, 2015): 699. http://dx.doi.org/10.1038/nrc4047.
Full textTaylor, Sarah J., Mark J. Arends, and Simon P. Langdon. "Inhibitors of the Fanconi anaemia pathway as potential antitumour agents for ovarian cancer." Exploration of Targeted Anti-tumor Therapy 1, no. 1 (February 29, 2020): 26–52. http://dx.doi.org/10.37349/etat.2020.00003.
Full textO'Connor, Kevin, Sofia Vidal-Cardenas, Haojian Zhang, Alfredo Rodriguez, Lisa Moreau, Chunyu Yang, Michael W. Epperly, et al. "Hyperactive Non-Canonical TGF-β Pathway Signaling in Fanconi Anemia Bone Marrow Stromal Cells Contributes to Growth Suppression." Blood 128, no. 22 (December 2, 2016): 1039. http://dx.doi.org/10.1182/blood.v128.22.1039.1039.
Full textMilletti, Giacomo, Luisa Strocchio, Daria Pagliara, Katia Girardi, Roberto Carta, Angela Mastronuzzi, Franco Locatelli, and Francesca Nazio. "Canonical and Noncanonical Roles of Fanconi Anemia Proteins: Implications in Cancer Predisposition." Cancers 12, no. 9 (September 20, 2020): 2684. http://dx.doi.org/10.3390/cancers12092684.
Full textLongerich, Simonne, Jian Li, Yong Xiong, Patrick Sung, and Gary M. Kupfer. "Stress and DNA repair biology of the Fanconi anemia pathway." Blood 124, no. 18 (October 30, 2014): 2812–19. http://dx.doi.org/10.1182/blood-2014-04-526293.
Full textParmar, Kalindi, Patrizia Vinciguerra, Susana Godinho, Abigail Hamilton, David Pellman, and Alan D. D'Andrea. "Cytokinesis Failure In Fanconi Anemia Pathway Deficient Hematopoietic Cells." Blood 116, no. 21 (November 19, 2010): 878. http://dx.doi.org/10.1182/blood.v116.21.878.878.
Full textSoulier, Jean, Thierry Leblanc, Jérôme Larghero, Hélène Dastot, Akiko Shimamura, Philippe Guardiola, Hélène Esperou, et al. "Detection of somatic mosaicism and classification of Fanconi anemia patients by analysis of the FA/BRCA pathway." Blood 105, no. 3 (February 1, 2005): 1329–36. http://dx.doi.org/10.1182/blood-2004-05-1852.
Full textZhang, Haojian, David Kozono, Kevin O'Connor, Alix Rousseau, Lisa Moreau, Emily Gaudiano, Joel S. Greenberger, et al. "TGF-β Pathway Inhibition Rescues the Function of Hematopoietic Stem and Progenitor Cells Derived from Patients with Fanconi Anemia." Blood 126, no. 23 (December 3, 2015): 297. http://dx.doi.org/10.1182/blood.v126.23.297.297.
Full textLevitus, Marieke, Hans Joenje, and Johan P. de Winter. "The Fanconi Anemia Pathway of Genomic Maintenance." Analytical Cellular Pathology 28, no. 1-2 (January 1, 2006): 3–29. http://dx.doi.org/10.1155/2006/974975.
Full textOda, Tsukasa, Toshiya Hayano, Hidenobu Miyaso, Nobuhiro Takahashi, and Takayuki Yamashita. "Hsp90 regulates the Fanconi anemia DNA damage response pathway." Blood 109, no. 11 (June 1, 2007): 5016–26. http://dx.doi.org/10.1182/blood-2006-08-038638.
Full textChlon, Timothy M., Elizabeth E. Hoskins, Sonya Ruiz-Torres, Christopher N. Mayhew, Kathryn A. Wikenheiser-Brokamp, Stella M. Davies, Parinda A. Mehta, Kasiani C. Myers, James M. Wells, and Susanne I. Wells. "Inducible Loss of the Fanconi Anemia Pathway in iPSC Causes Rapid Cell Cycle Arrest and Apoptosis through ATM/ATR and p53 Signaling." Blood 124, no. 21 (December 6, 2014): 3528. http://dx.doi.org/10.1182/blood.v124.21.3528.3528.
Full textMedhurst, Annette L., El Houari Laghmani, Jurgen Steltenpool, Miriam Ferrer, Chantal Fontaine, Jan de Groot, Martin A. Rooimans, et al. "Evidence for subcomplexes in the Fanconi anemia pathway." Blood 108, no. 6 (September 15, 2006): 2072–80. http://dx.doi.org/10.1182/blood-2005-11-008151.
Full textLyakhovich, Alex, and Jordi Surralles. "New Roads to FA/BRCA Pathway: H2AX." Cell Cycle 6, no. 9 (May 2, 2007): 1019–23. http://dx.doi.org/10.4161/cc.6.9.4223.
Full textD'Andrea, Alan D. "Abstract IA002: Inherited DNA repair defects and premature aging." Cancer Research 83, no. 2_Supplement_1 (January 15, 2023): IA002. http://dx.doi.org/10.1158/1538-7445.agca22-ia002.
Full textGhosal, Kajal, Christian Agatemor, Richard I. Han, Amy T. Ku, Sabu Thomas, and Sudit Mukherjee. "Fanconi Anemia DNA Repair Pathway as a New Mechanism to Exploit Cancer Drug Resistance." Mini-Reviews in Medicinal Chemistry 20, no. 9 (May 27, 2020): 779–87. http://dx.doi.org/10.2174/1389557520666200103114556.
Full textChlon, Timothy Michael, Susanne I. Wells, Sonya Ruiz-Torres, Matthew Kuhar, and James M. Wells. "Models of Pluripotent and Somatic Stem Cells to Study Tissue-Specific Sensitivities in Fanconi Anemia." Blood 126, no. 23 (December 3, 2015): 168. http://dx.doi.org/10.1182/blood.v126.23.168.168.
Full textLandais, Igor, Aiming Sun, Stacie N. Stone, Alexandra Sobeck, James P. Snyder, and Maureen Hoatlin. "A Novel Cell-Free Assay Identifies the Curcumin Analog EF24 as a Potent Inhibitor of the Fanconi Anemia Pathway." Blood 112, no. 11 (November 16, 2008): 2654. http://dx.doi.org/10.1182/blood.v112.11.2654.2654.
Full textSpardy, Nicole, Anette Duensing, Domonique Charles, Nathan Haines, Tomomi Nakahara, Paul F. Lambert, and Stefan Duensing. "The Human Papillomavirus Type 16 E7 Oncoprotein Activates the Fanconi Anemia (FA) Pathway and Causes Accelerated Chromosomal Instability in FA Cells." Journal of Virology 81, no. 23 (September 26, 2007): 13265–70. http://dx.doi.org/10.1128/jvi.01121-07.
Full textGarcía-de-Teresa, Benilde, Alfredo Rodríguez, and Sara Frias. "Chromosome Instability in Fanconi Anemia: From Breaks to Phenotypic Consequences." Genes 11, no. 12 (December 21, 2020): 1528. http://dx.doi.org/10.3390/genes11121528.
Full textShimamura, Akiko, Rocio Montes de Oca, John L. Svenson, Nicholas Haining, Lisa A. Moreau, David G. Nathan, and Alan D. D'Andrea. "A novel diagnostic screen for defects in the Fanconi anemia pathway." Blood 100, no. 13 (December 15, 2002): 4649–54. http://dx.doi.org/10.1182/blood-2002-05-1399.
Full textIshiai, Masamichi. "Regulation of the Fanconi Anemia DNA Repair Pathway by Phosphorylation and Monoubiquitination." Genes 12, no. 11 (November 5, 2021): 1763. http://dx.doi.org/10.3390/genes12111763.
Full textPannia, Emanuela, Rola Hammoud, Ruslan Kubant, Rebecca Simonian, Zdenka Pausova, Erland Arning, Teodoro Bottiglieri, and G. Harvey Anderson. "High 5MTHF, but Not Folic Acid During Pregnancy, Alters Hypothalamic Regulatory Pathways and Associates with Post-Partum Weight-Gain in Wistar Rat Mothers." Current Developments in Nutrition 4, Supplement_2 (May 29, 2020): 1230. http://dx.doi.org/10.1093/cdn/nzaa057_046.
Full textSobeck, A., S. Stone, and M. E. Hoatlin. "DNA Structure-Induced Recruitment and Activation of the Fanconi Anemia Pathway Protein FANCD2." Molecular and Cellular Biology 27, no. 12 (April 9, 2007): 4283–92. http://dx.doi.org/10.1128/mcb.02196-06.
Full textMüller, Lars U. W., Michael D. Milsom, Chad E. Harris, Rutesh Vyas, Kristina M. Brumme, Kalindi Parmar, Lisa A. Moreau, et al. "Overcoming reprogramming resistance of Fanconi anemia cells." Blood 119, no. 23 (June 7, 2012): 5449–57. http://dx.doi.org/10.1182/blood-2012-02-408674.
Full textDan, Chenchen, Hongjing Pei, Buzhe Zhang, Xuan Zheng, Dongmei Ran, and Changzheng Du. "Fanconi anemia pathway and its relationship with cancer." Genome Instability & Disease 2, no. 3 (June 2021): 175–83. http://dx.doi.org/10.1007/s42764-021-00043-0.
Full textLiu, Hengzhou, Deep Patel, Yifu Chen, Luke T. Roling, and Wenzhen Li. "Elucidating Pathways to Electrochemical Reduction of Furfural Via Tailoring Interfacial Environments Toward Selective Production of Valuable Furanic Chemicals." ECS Meeting Abstracts MA2022-01, no. 56 (July 7, 2022): 2347. http://dx.doi.org/10.1149/ma2022-01562347mtgabs.
Full textRominiyi, Ola, Katie Myers, Natividad Gomez-Roman, Nikita Lad, Dawoud Dar, David Jellinek, Anthony Chalmers, et al. "RDNA-12. THE FANCONI ANAEMIA (FA) PATHWAY AND GLIOBLASTOMA: A NEW FOUNDATION FOR DNA DAMAGE RESPONSE TARGETED COMBINATIONS." Neuro-Oncology 21, Supplement_6 (November 2019): vi209. http://dx.doi.org/10.1093/neuonc/noz175.871.
Full textLevitus, Marieke, Martin A. Rooimans, Jûrgen Steltenpool, Nicolle F. C. Cool, Anneke B. Oostra, Christopher G. Mathew, Maureen E. Hoatlin, et al. "Heterogeneity in Fanconi anemia: evidence for 2 new genetic subtypes." Blood 103, no. 7 (April 1, 2004): 2498–503. http://dx.doi.org/10.1182/blood-2003-08-2915.
Full textNagareddy, Bhavika, Arafat Khan, and Hyungjin Kim. "Acetylation modulates the Fanconi anemia pathway by protecting FAAP20 from ubiquitin-mediated proteasomal degradation." Journal of Biological Chemistry 295, no. 40 (August 6, 2020): 13887–901. http://dx.doi.org/10.1074/jbc.ra120.015288.
Full textAli, Abdullah Mahmood, Arun Pradhan, Thiyam Ramsingh Singh, Changhu Du, Jie Li, Kebola Wahengbam, Elke Grassman, Arleen D. Auerbach, Qishen Pang, and Amom Ruhikanta Meetei. "FAAP20: a novel ubiquitin-binding FA nuclear core-complex protein required for functional integrity of the FA-BRCA DNA repair pathway." Blood 119, no. 14 (April 5, 2012): 3285–94. http://dx.doi.org/10.1182/blood-2011-10-385963.
Full textvan der Vusse, Ger J., Theo Arts, James B. Bassingthwaighte, and Robert S. Reneman. "Intra-cardiac transfer of fatty acids from capillary to cardiomyocyte." PLOS ONE 17, no. 1 (January 28, 2022): e0261288. http://dx.doi.org/10.1371/journal.pone.0261288.
Full textKim, Joon Sung, Se-Hong Kim, Seong Hoon Lim, Sun Im, Bo Young Hong, Jeehae Oh, and Youngkook Kim. "Degeneration of the Inferior Cerebellar Peduncle After Middle Cerebral Artery Stroke." Stroke 50, no. 10 (October 2019): 2700–2707. http://dx.doi.org/10.1161/strokeaha.119.025723.
Full textSertorio, Mathieu, Surya Amarachintha, Andrew Wilson, and Qishen Pang. "Fancd2 Deficiency Impairs Autophagy Via Deregulating The Ampk/Foxo3a/Akt Pathway." Blood 122, no. 21 (November 15, 2013): 3713. http://dx.doi.org/10.1182/blood.v122.21.3713.3713.
Full textKolinjivadi, Arun Mouli, Wayne Crismani, and Joanne Ngeow. "Emerging functions of Fanconi anemia genes in replication fork protection pathways." Human Molecular Genetics 29, R2 (May 18, 2020): R158—R164. http://dx.doi.org/10.1093/hmg/ddaa087.
Full textLi, Landing, Winnie Tan, and Andrew J. Deans. "Structural insight into FANCI–FANCD2 monoubiquitination." Essays in Biochemistry 64, no. 5 (July 29, 2020): 807–17. http://dx.doi.org/10.1042/ebc20200001.
Full text&NA;. "FA pathway repairs chemoʼs damage to cancer cells." Oncology Times UK 7, no. 3 (March 2010): 4. http://dx.doi.org/10.1097/01.otu.0000398566.79064.ee.
Full textSuzuki, Naoya, Asuka Hira, Akira Niwa, Megumu Saito, Keitaro Matsuo, Tatsutoshi Nakahata, Minoru Takata, and Miharu Yabe. "Mesodermal Development From Reprogrammed Fanconi Anemia Cells Is Affected by ALDH2 Enzymatic Activity." Blood 120, no. 21 (November 16, 2012): 648. http://dx.doi.org/10.1182/blood.v120.21.648.648.
Full textGuo, T., G. Cao, Y. Li, Z. Zhang, J. E. Nör, B. H. Clarkson, and J. Liu. "Signals in Stem Cell Differentiation on Fluorapatite-Modified Scaffolds." Journal of Dental Research 97, no. 12 (July 11, 2018): 1331–38. http://dx.doi.org/10.1177/0022034518788037.
Full textYarde, Danielle N., Lori A. Hazlehurst, Vasco A. Oliveira, Qing Chen, and William S. Dalton. "Bortezomib Enhances Melphalan Response by Altering Fanconi Anemia (FA)/BRCA Pathway Expression and Function." Blood 108, no. 11 (November 16, 2006): 840. http://dx.doi.org/10.1182/blood.v108.11.840.840.
Full textWilliams, Stacy A., James B. Wilson, Allison P. Clark, Alyssa N. Mitson-Salazar, Allen E. Bale, Nigel J. Jones, and Gary M. Kupfer. "Functional and Physical Interaction Between the Mismatch Repair and the FA-BRCA Pathways." Blood 116, no. 21 (November 19, 2010): 3370. http://dx.doi.org/10.1182/blood.v116.21.3370.3370.
Full textShain, Kenneth H., Liang Nong, Danielle Yarde, Vasco Oliveira, and William S. Dalton. "Selected Resistance to Topoisomerase II Inhibitors Correlates with the Over Expression of FANCF In a Fanconi Anemia/BRCA DNA Repair Pathway Independent Manner." Blood 116, no. 21 (November 19, 2010): 3372. http://dx.doi.org/10.1182/blood.v116.21.3372.3372.
Full textVinciguerra, Patrizia, Susana Godinho, Kalindi Parmar, David Pellman, and Alan D'Andrea. "Cytokinesis Failure in Fanconi Anemia Pathway Deficient Murine Hematopoietic Stem Cells." Blood 114, no. 22 (November 20, 2009): 495. http://dx.doi.org/10.1182/blood.v114.22.495.495.
Full textLehto, Jemina, Anna Huguet Ninou, Dimitrios Chioureas, Jos Jonkers, and Nina M. S. Gustafsson. "Targeting CX3CR1 Suppresses the Fanconi Anemia DNA Repair Pathway and Synergizes with Platinum." Cancers 13, no. 6 (March 22, 2021): 1442. http://dx.doi.org/10.3390/cancers13061442.
Full textCheung, Ronald S., Maria Castella, and Toshiyasu Taniguchi. "Disparate Requirements for the Phosphorylation of Distinct Sites on the Fanconi Anemia Group I Protein." Blood 124, no. 21 (December 6, 2014): 358. http://dx.doi.org/10.1182/blood.v124.21.358.358.
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