Journal articles on the topic 'Pateamine'
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Matthews, James H., David R. Maass, Peter T. Northcote, Paul H. Atkinson, and Paul H. Teesdale-Spittle. "The Cellular Target Specificity of Pateamine A." Zeitschrift für Naturforschung C 68, no. 9-10 (October 1, 2013): 406–15. http://dx.doi.org/10.1515/znc-2013-9-1008.
Full textDang, Yongjun, Nancy Kedersha, Woon-Kai Low, Daniel Romo, Myriam Gorospe, Randal Kaufman, Paul Anderson, and Jun O. Liu. "Eukaryotic Initiation Factor 2α-independent Pathway of Stress Granule Induction by the Natural Product Pateamine A." Journal of Biological Chemistry 281, no. 43 (September 2, 2006): 32870–78. http://dx.doi.org/10.1074/jbc.m606149200.
Full textPattenden, Gerald, Douglas J. Critcher, and Modesto Remuiñán. "Total synthesis of ()-pateamine A, a novel immunosuppressive agent from Mycale sp." Canadian Journal of Chemistry 82, no. 2 (February 1, 2004): 353–65. http://dx.doi.org/10.1139/v03-199.
Full textHemi Cumming, A., Sarah L. Brown, Xu Tao, Claire Cuyamendous, Jessica J. Field, John H. Miller, Joanne E. Harvey, and Paul H. Teesdale-Spittle. "Synthesis of a simplified triazole analogue of pateamine A." Organic & Biomolecular Chemistry 14, no. 22 (2016): 5117–27. http://dx.doi.org/10.1039/c6ob00086j.
Full textKorneeva, Nadejda L. "Translational Dysregulation by Pateamine A." Chemistry & Biology 14, no. 1 (January 2007): 5–7. http://dx.doi.org/10.1016/j.chembiol.2007.01.003.
Full textKommaraju, Sai Shilpa, Julieta Aulicino, Shruthi Gobbooru, Jing Li, Mingzhao Zhu, Daniel Romo, and Woon-Kai Low. "Investigation of the mechanism of action of a potent pateamine A analog, des-methyl, des-amino pateamine A (DMDAPatA)." Biochemistry and Cell Biology 98, no. 4 (August 2020): 502–10. http://dx.doi.org/10.1139/bcb-2019-0307.
Full textMatthews, James H., David R. Maass, Peter T. Northcote, Paul H. Atkinson, and Paul H. Teesdale-Spittle. "The Cellular Target Specifi city of Pateamine A." Zeitschrift für Naturforschung C 68 (2013): 0406. http://dx.doi.org/10.5560/znc.2013.68c0406.
Full textKuznetsov, Galina, Qunli Xu, Lori Rudolph-Owen, Karen TenDyke, Junke Liu, Murray Towle, Nanding Zhao, et al. "Potent in vitro and in vivo anticancer activities of des-methyl, des-amino pateamine A, a synthetic analogue of marine natural product pateamine A." Molecular Cancer Therapeutics 8, no. 5 (May 2009): 1250–60. http://dx.doi.org/10.1158/1535-7163.mct-08-1026.
Full textZhuo, Chun-Xiang, and Alois Fürstner. "Catalysis-Based Total Syntheses of Pateamine A and DMDA-Pat A." Journal of the American Chemical Society 140, no. 33 (July 28, 2018): 10514–23. http://dx.doi.org/10.1021/jacs.8b05094.
Full textLow, Woon-Kai, Yongjun Dang, Tilman Schneider-Poetsch, Zonggao Shi, Nam Song Choi, William C. Merrick, Daniel Romo, and Jun O. Liu. "Inhibition of Eukaryotic Translation Initiation by the Marine Natural Product Pateamine A." Molecular Cell 20, no. 5 (December 2005): 709–22. http://dx.doi.org/10.1016/j.molcel.2005.10.008.
Full textNorthcote, Peter T., John W. Blunt, and Murray H. G. Munro. "Pateamine: a potent cytotoxin from the New Zealand Marine sponge, mycale sp." Tetrahedron Letters 32, no. 44 (October 1991): 6411–14. http://dx.doi.org/10.1016/0040-4039(91)80182-6.
Full textParikh, D., J. Dougan, J. Li, D. Romo, N. J. Moorman, L. M. Graves, and P. R. Graves. "Des-methyl, Des-amino pateamine A, a Synthetic Analogue of Marine Natural Product Pateamine A, Sensitizes Non-small Cell Lung Cancer Cells to Radiation and Enhances BAX Expression." International Journal of Radiation Oncology*Biology*Physics 84, no. 3 (November 2012): S701—S702. http://dx.doi.org/10.1016/j.ijrobp.2012.07.1875.
Full textDean, Andrea, Thien Nguyen, Nathan Cox, Matthew Cooper, Kristy L. Richards, Thomas C. Shea, Nathaniel Moorman, and Lee Graves. "Investigation of the Novel Anti-Leukemia Effects of the Marine Compound Pateamine A." Blood 120, no. 21 (November 16, 2012): 2437. http://dx.doi.org/10.1182/blood.v120.21.2437.2437.
Full textBordeleau, Marie-Eve, Regina Cencic, Lisa Lindqvist, Monika Oberer, Peter Northcote, Gerhard Wagner, and Jerry Pelletier. "RNA-Mediated Sequestration of the RNA Helicase eIF4A by Pateamine A Inhibits Translation Initiation." Chemistry & Biology 13, no. 12 (December 2006): 1287–95. http://dx.doi.org/10.1016/j.chembiol.2006.10.005.
Full textGonzález-Almela, Esther, Miguel Angel Sanz, Manuel García-Moreno, Peter Northcote, Jerry Pelletier, and Luis Carrasco. "Differential action of pateamine A on translation of genomic and subgenomic mRNAs from Sindbis virus." Virology 484 (October 2015): 41–50. http://dx.doi.org/10.1016/j.virol.2015.05.002.
Full textCritcher, Douglas J., and Gerald Pattenden. "Synthetic studies towards pateamine, a novel thiazole-based 19-membered bis-lactone from Mycale sp." Tetrahedron Letters 37, no. 50 (December 1996): 9107–10. http://dx.doi.org/10.1016/s0040-4039(96)02098-9.
Full textRzasa, Robert M., Helene A. Shea, and Daniel Romo. "Total Synthesis of the Novel, Immunosuppressive Agent (−)-Pateamine A fromMycalesp. Employing a β-Lactam-Based Macrocyclization." Journal of the American Chemical Society 120, no. 3 (January 1998): 591–92. http://dx.doi.org/10.1021/ja973549f.
Full textDang, Yongjun, Woon-Kai Low, Jing Xu, Niels H. Gehring, Harry C. Dietz, Daniel Romo, and Jun O. Liu. "Inhibition of Nonsense-mediated mRNA Decay by the Natural Product Pateamine A through Eukaryotic Initiation Factor 4AIII." Journal of Biological Chemistry 284, no. 35 (July 1, 2009): 23613–21. http://dx.doi.org/10.1074/jbc.m109.009985.
Full textRemuiñán, Modesto J., and Gerald Pattenden. "Total synthesis of ()-pateamine, a novel polyene bis-macrolide with immunosuppressive activity from the sponge Mycale sp." Tetrahedron Letters 41, no. 38 (September 2000): 7367–71. http://dx.doi.org/10.1016/s0040-4039(00)01241-7.
Full textLow, Woon-Kai, Jing Li, Mingzhao Zhu, Sai Shilpa Kommaraju, Janki Shah-Mittal, Ken Hull, Jun O. Liu, and Daniel Romo. "Second-generation derivatives of the eukaryotic translation initiation inhibitor pateamine A targeting eIF4A as potential anticancer agents." Bioorganic & Medicinal Chemistry 22, no. 1 (January 2014): 116–25. http://dx.doi.org/10.1016/j.bmc.2013.11.046.
Full textCRITCHER, D. J., and G. PATTENDEN. "ChemInform Abstract: Synthetic Studies Towards Pateamine, a Novel Thiazole-Based 19- Membered Bis-lactone from Mycale sp." ChemInform 28, no. 15 (August 4, 2010): no. http://dx.doi.org/10.1002/chin.199715224.
Full textRomo, Daniel, Robert M. Rzasa, Helene A. Shea, Kaapjoo Park, Joseph M. Langenhan, Luo Sun, Alexander Akhiezer, and Jun O. Liu. "Total Synthesis and Immunosuppressive Activity of (−)-Pateamine A and Related Compounds: Implementation of a β-Lactam-Based Macrocyclization." Journal of the American Chemical Society 120, no. 47 (December 1998): 12237–54. http://dx.doi.org/10.1021/ja981846u.
Full textNaineni, Sai Kiran, Jason Liang, Kenneth Hull, Regina Cencic, Mingzhao Zhu, Peter Northcote, Paul Teesdale-Spittle, Daniel Romo, Bhushan Nagar, and Jerry Pelletier. "Functional mimicry revealed by the crystal structure of an eIF4A:RNA complex bound to the interfacial inhibitor, desmethyl pateamine A." Cell Chemical Biology 28, no. 6 (June 2021): 825–34. http://dx.doi.org/10.1016/j.chembiol.2020.12.006.
Full textLow, Woon-Kai, Yongjun Dang, Shridhar Bhat, Daniel Romo, and Jun O. Liu. "Substrate-Dependent Targeting of Eukaryotic Translation Initiation Factor 4A by Pateamine A: Negation of Domain-Linker Regulation of Activity." Chemistry & Biology 14, no. 6 (June 2007): 715–27. http://dx.doi.org/10.1016/j.chembiol.2007.05.012.
Full textRemuinan, Modesto J., and Gerald Pattenden. "ChemInform Abstract: Total Synthesis of (-)-Pateamine, a Novel Polyene Bis-macrolide with Immunosuppressive Activity from the Sponge Mycale sp." ChemInform 31, no. 50 (December 12, 2000): no. http://dx.doi.org/10.1002/chin.200050222.
Full textXu, Tao, Claire Cuyamendous, Sarah L. Brown, Sarah K. Andreassend, Hemi Cumming, Gary B. Evans, Paul H. Teesdale-Spittle, and Joanne E. Harvey. "Gold(I)-catalyzed, one-pot, oxidative formation of 2,4-disubstituted thiazoles: Application to the synthesis of a pateamine-related macrodiolide." Tetrahedron 88 (May 2021): 132109. http://dx.doi.org/10.1016/j.tet.2021.132109.
Full textRomo, Daniel, Robert M. Rzasa, Helene A. Shea, Kaapjoo Park, Joseph M. Langenhan, Luo Sun, Alexander Akhiezer, and Jun O. Liu. "ChemInform Abstract: Total Synthesis of Immunosuppressive Activity of (-)-Pateamine A and Related Compounds: Implementation of a β-Lactam-Based Macrocyclization." ChemInform 30, no. 18 (June 16, 2010): no. http://dx.doi.org/10.1002/chin.199918232.
Full textRZASA, R. M., H. A. SHEA, and D. ROMO. "ChemInform Abstract: Total Synthesis of the Novel, Immunosuppressive Agent (-)-Pateamine A from Mycale sp. Employing a β-Lactam-Based Macrocyclization." ChemInform 29, no. 24 (June 22, 2010): no. http://dx.doi.org/10.1002/chin.199824204.
Full textZhuo, Chun-Xiang, and Alois Fürstner. "Concise Synthesis of a Pateamine A Analogue with In Vivo Anticancer Activity Based on an Iron-Catalyzed Pyrone Ring Opening/Cross-Coupling." Angewandte Chemie International Edition 55, no. 20 (April 8, 2016): 6051–56. http://dx.doi.org/10.1002/anie.201602125.
Full textZhuo, Chun-Xiang, and Alois Fürstner. "Concise Synthesis of a Pateamine A Analogue with In Vivo Anticancer Activity Based on an Iron-Catalyzed Pyrone Ring Opening/Cross-Coupling." Angewandte Chemie 128, no. 20 (April 8, 2016): 6155–60. http://dx.doi.org/10.1002/ange.201602125.
Full textRomo, Daniel, Nam Song Choi, Shukun Li, Ingrid Buchler, Zonggao Shi, and Jun O. Liu. "Evidence for Separate Binding and Scaffolding Domains in the Immunosuppressive and Antitumor Marine Natural Product, Pateamine A: Design, Synthesis, and Activity Studies Leading to a Potent Simplified Derivative." Journal of the American Chemical Society 126, no. 34 (September 2004): 10582–88. http://dx.doi.org/10.1021/ja040065s.
Full textPal, Ipsita, Yu Ri Kim, Sohani Das Sharma, Prabhjot S. Mundi, Andre M. Grilo, Luke E. Berchowitz, Mingzhao Zhu, et al. "Targeting eIF4A Using MZ-735 Potently Induces Cell Death in Lymphoma Cells and Rapidly Represses mRNA Translation at the Global Level and in C-MYC and Other Oncogenes." Blood 134, Supplement_1 (November 13, 2019): 4067. http://dx.doi.org/10.1182/blood-2019-131816.
Full textRzasa, R. "Structural and Synthetic Studies of the Pateamines: Synthesis and Absolute Configuration of the Hydroxydienoate Fragment." Tetrahedron Letters 36, no. 30 (July 24, 1995): 5307–10. http://dx.doi.org/10.1016/00404-0399(50)10219-.
Full textRust, Michael, Eric J. N. Helfrich, Michael F. Freeman, Pakjira Nanudorn, Christopher M. Field, Christian Rückert, Tomas Kündig, et al. "A multiproducer microbiome generates chemical diversity in the marine sponge Mycale hentscheli." Proceedings of the National Academy of Sciences 117, no. 17 (April 14, 2020): 9508–18. http://dx.doi.org/10.1073/pnas.1919245117.
Full textRZASA, R. M., D. ROMO, D. J. STIRLING, J. W. BLUNT, and M. H. G. MUNRO. "ChemInform Abstract: Structural and Synthetic Studies of the Pateamines: Synthesis and Absolute Configuration of the Hydroxydienoate Fragment." ChemInform 26, no. 44 (August 17, 2010): no. http://dx.doi.org/10.1002/chin.199544268.
Full text"Synthesis of (–)-Pateamine A." Synfacts 14, no. 11 (October 18, 2018): 1114. http://dx.doi.org/10.1055/s-0037-1611234.
Full textLow, Woon‐Kai, Yongjun Dang, Tilman Schneider‐Poetsch, Zonggao Shi, Nam Song Choi, William C. Merrick, Daniel Romo, and Jun O. Liu. "Inhibition of Eukaryotic Translation Initiation by the Natural Product Pateamine A." FASEB Journal 20, no. 5 (March 2006). http://dx.doi.org/10.1096/fasebj.20.5.lb46-a.
Full textDi Marco, Sergio, Anne Cammas, Xian Jin Lian, Erzsebet Nagy Kovacs, Jennifer F. Ma, Derek T. Hall, Rachid Mazroui, John Richardson, Jerry Pelletier, and Imed Eddine Gallouzi. "The translation inhibitor pateamine A prevents cachexia-induced muscle wasting in mice." Nature Communications 3, no. 1 (January 2012). http://dx.doi.org/10.1038/ncomms1899.
Full textPattenden, Gerald, Douglas J. Critcher, and Modesto Remuinan. "Total Synthesis of (-)-Pateamine A, a Novel Immunosuppressive Agent from Mycale sp." ChemInform 35, no. 34 (August 24, 2004). http://dx.doi.org/10.1002/chin.200434238.
Full text"Towards Pateamine. A Comparison of Palladium-catalysed sp2-sp2Coupling Protocols to Polyene Macrolides." Synlett 2000, no. 11 (2000): 1661–63. http://dx.doi.org/10.1055/s-2000-7930.
Full textPopa, Alexandra, Kevin Lebrigand, Pascal Barbry, and Rainer Waldmann. "Pateamine A-sensitive ribosome profiling reveals the scope of translation in mouse embryonic stem cells." BMC Genomics 17, no. 1 (January 14, 2016). http://dx.doi.org/10.1186/s12864-016-2384-0.
Full textKOMMARAJU, SAI SHILPA, Jing Li, Mingzhao Zhu, Daniel Romo, and Woon‐Kai Low. "In vitro structure/activity relationship studies of second generation derivatives of the translation initiation inhibitor desmethyl, desamino‐Pateamine A." FASEB Journal 27, S1 (April 2013). http://dx.doi.org/10.1096/fasebj.27.1_supplement.lb69.
Full textStorey, Mathew A., Sarah K. Andreassend, Joe Bracegirdle, Alistair Brown, Robert A. Keyzers, David F. Ackerley, Peter T. Northcote, and Jeremy G. Owen. "Metagenomic Exploration of the Marine Sponge Mycale hentscheli Uncovers Multiple Polyketide-Producing Bacterial Symbionts." mBio 11, no. 2 (March 24, 2020). http://dx.doi.org/10.1128/mbio.02997-19.
Full textKommaraju, Sai Shilpa, Julieta Aulicino, Jing Li, Mingzhao Zhu, Daniel Romo, and Woon‐Kai Low. "Re‐evaluation of desmethyl, desamino‐PateamineA targeting of eukaryotic translation initiation factor 4F (975.2)." FASEB Journal 28, S1 (April 2014). http://dx.doi.org/10.1096/fasebj.28.1_supplement.975.2.
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