Journal articles on the topic 'Patched Gene'
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Ellis, Tammy, Ian Smyth, Emily Riley, Scott Graham, Kate Elliot, Monica Narang, Graham F. Kay, Carol Wicking, and Brandon Wainwright. "Patched 1 conditional null allele in mice." genesis 36, no. 3 (July 2003): 158–61. http://dx.doi.org/10.1002/gene.10208.
Full textPhillips, R. G., I. J. Roberts, P. W. Ingham, and J. R. Whittle. "The Drosophila segment polarity gene patched is involved in a position-signalling mechanism in imaginal discs." Development 110, no. 1 (September 1, 1990): 105–14. http://dx.doi.org/10.1242/dev.110.1.105.
Full textIngham, Philip W. "The patched gene in development and cancer." Current Opinion in Genetics & Development 8, no. 1 (February 1998): 88–94. http://dx.doi.org/10.1016/s0959-437x(98)80067-1.
Full textIngham, Philip W. "The patched gene in development and cancer." Current Opinion in Genetics & Development 8, no. 3 (June 1998): 371. http://dx.doi.org/10.1016/s0959-437x(98)80096-8.
Full textHidalgo, A., and P. Ingham. "Cell patterning in the Drosophila segment: spatial regulation of the segment polarity gene patched." Development 110, no. 1 (September 1, 1990): 291–301. http://dx.doi.org/10.1242/dev.110.1.291.
Full textMarigo, V., M. P. Scott, R. L. Johnson, L. V. Goodrich, and C. J. Tabin. "Conservation in hedgehog signaling: induction of a chicken patched homolog by Sonic hedgehog in the developing limb." Development 122, no. 4 (April 1, 1996): 1225–33. http://dx.doi.org/10.1242/dev.122.4.1225.
Full textConcordet, J. P., K. E. Lewis, J. W. Moore, L. V. Goodrich, R. L. Johnson, M. P. Scott, and P. W. Ingham. "Spatial regulation of a zebrafish patched homologue reflects the roles of sonic hedgehog and protein kinase A in neural tube and somite patterning." Development 122, no. 9 (September 1, 1996): 2835–46. http://dx.doi.org/10.1242/dev.122.9.2835.
Full textCapdevila, J., F. Pariente, J. Sampedro, J. L. Alonso, and I. Guerrero. "Subcellular localization of the segment polarity protein patched suggests an interaction with the wingless reception complex in Drosophila embryos." Development 120, no. 4 (April 1, 1994): 987–98. http://dx.doi.org/10.1242/dev.120.4.987.
Full textIngham, P. W., A. M. Taylor, and Y. Nakano. "Role of the Drosophila patched gene in positional signalling." Nature 353, no. 6340 (September 1991): 184–87. http://dx.doi.org/10.1038/353184a0.
Full textTakabatake, Takashi, Masanori Ogawa, Tadashi C. Takahashi, Makoto Mizuno, Mitsumasa Okamoto, and Kazuhito Takeshima. "Hedgehog and patched gene expression in adult ocular tissues." FEBS Letters 410, no. 2-3 (June 30, 1997): 485–89. http://dx.doi.org/10.1016/s0014-5793(97)00645-5.
Full textGemmill, Robert M., James D. West, Ferenc Boldog, Naotake Tanaka, Linda J. Robinson, David I. Smith, Frederick Li, and Harry A. Drabkin. "The hereditary renal cell carcinoma 3;8 translocation fuses FHIT to a patched-related gene, TRC8." Proceedings of the National Academy of Sciences 95, no. 16 (August 4, 1998): 9572–77. http://dx.doi.org/10.1073/pnas.95.16.9572.
Full textNakatomi, M., I. Morita, K. Eto, and M. S. Ota. "Sonic Hedgehog Signaling is Important in Tooth Root Development." Journal of Dental Research 85, no. 5 (May 2006): 427–31. http://dx.doi.org/10.1177/154405910608500506.
Full textNagano, T., M. Ueda, and M. Ichihashi. "062 Expression of human patched gene in various skin neoplasms." Journal of Dermatological Science 15, no. 2 (August 1997): 113. http://dx.doi.org/10.1016/s0923-1811(97)81765-3.
Full textYan, Taiqiang, Mark Angelini, Benjamin A. Alman, Irene L. Andrulis, and Jay S. Wunder. "PATCHED-ONE or SMOOTHENED Gene Mutations Are Infrequent in Chondrosarcoma." Clinical Orthopaedics and Related Research 466, no. 9 (June 10, 2008): 2184–89. http://dx.doi.org/10.1007/s11999-008-0332-2.
Full textGoodrich, L. V., R. L. Johnson, L. Milenkovic, J. A. McMahon, and M. P. Scott. "Conservation of the hedgehog/patched signaling pathway from flies to mice: induction of a mouse patched gene by Hedgehog." Genes & Development 10, no. 3 (February 1, 1996): 301–12. http://dx.doi.org/10.1101/gad.10.3.301.
Full textHiltunen, Mimmu K., Alex J. Timmis, Maren Thomsen, Danai S. Gkotsi, Hideo Iwaï, Orquidea M. Ribeiro, Adrian Goldman, and Natalia A. Riobo-Del Galdo. "PTCHD1 Binds Cholesterol but Not Sonic Hedgehog, Suggesting a Distinct Cellular Function." International Journal of Molecular Sciences 24, no. 3 (January 31, 2023): 2682. http://dx.doi.org/10.3390/ijms24032682.
Full textLam, Ching-Wan, Chi-Yan Leung, Kam-Cheong Lee, Jingwu Xie, Fai-Man Lo, Tak-Shing Au, Sui-Fan Tong, Miu-Kuen Poon, Loi-Yuen Chan, and Nai-Ming Luk. "Novel mutations in the PATCHED gene in basal cell nevus syndrome." Molecular Genetics and Metabolism 76, no. 1 (May 2002): 57–61. http://dx.doi.org/10.1016/s1096-7192(02)00021-5.
Full textBejsovec, A., and E. Wieschaus. "Segment polarity gene interactions modulate epidermal patterning in Drosophila embryos." Development 119, no. 2 (October 1, 1993): 501–17. http://dx.doi.org/10.1242/dev.119.2.501.
Full textKim, Juhan, Jake J. Flood, Michael R. Kristofich, Cyrus Gidfar, Andrew B. Morgenthaler, Tobias Fuhrer, Uwe Sauer, et al. "Hidden resources in the Escherichia coli genome restore PLP synthesis and robust growth after deletion of the essential gene pdxB." Proceedings of the National Academy of Sciences 116, no. 48 (November 11, 2019): 24164–73. http://dx.doi.org/10.1073/pnas.1915569116.
Full textStone, Donna M., Mary Hynes, Mark Armanini, Todd A. Swanson, Qimin Gu, Ronald L. Johnson, Matthew P. Scott, et al. "The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog." Nature 384, no. 6605 (November 1996): 129–34. http://dx.doi.org/10.1038/384129a0.
Full textSampedro, Javier, and Isabel Guerrero. "Unrestricted expression of the Drosophila gene patched allows a normal segment polarity." Nature 353, no. 6340 (September 1991): 187–90. http://dx.doi.org/10.1038/353187a0.
Full textLing, Gao, Afshin Ahmadian, Åsa Persson, Anne Birgitte Undén, Gijs Afink, Cecilia Williams, Mathias Uhlén, Rune Toftgård, Joakim Lundeberg, and Fredrik Pontén. "PATCHED and p53 gene alterations in sporadic and hereditary basal cell cancer." Oncogene 20, no. 53 (November 2001): 7770–78. http://dx.doi.org/10.1038/sj.onc.1204946.
Full textCajaiba, Mariana M., Allen E. Bale, Mayra Alvarez-Franco, Joseph McNamara, and Miguel Reyes-Múgica. "Rhabdomyosarcoma, Wilms tumor, and deletion of the patched gene in Gorlin syndrome." Nature Clinical Practice Oncology 3, no. 10 (October 2006): 575–80. http://dx.doi.org/10.1038/ncponc0608.
Full textKitano, Hisataka, Yuu Koyama, Masamichi Komiya, Naoyuki Sato, and Tomohiro Nakayama. "Basal cell nevus syndrome: New mutation of the patched homologue 1 gene." Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology 26, no. 4 (October 2014): 506–10. http://dx.doi.org/10.1016/j.ajoms.2013.04.016.
Full textMotoyama, Jun, Takashi Takabatake, Kazuhito Takeshima, and Chi-chung Hui. "Ptch2, a second mouse Patched gene is co-expressed with Sonic hedgehog." Nature Genetics 18, no. 2 (February 1998): 104–6. http://dx.doi.org/10.1038/ng0298-104.
Full textYan, Taiqiang, Mark Angelini, Benjamin A. Alman, Irene L. Andrulis, and Jay S. Wunder. "Erratum to: PATCHED-ONE or SMOOTHENED Gene Mutations Are Infrequent in Chondrosarcoma." Clinical Orthopaedics and Related Research® 467, no. 12 (October 22, 2009): 3356. http://dx.doi.org/10.1007/s11999-009-1134-x.
Full textCapdevila, J., M. P. Estrada, E. Sánchez-Herrero, and I. Guerrero. "The Drosophila segment polarity gene patched interacts with decapentaplegic in wing development." EMBO Journal 13, no. 1 (January 1994): 71–82. http://dx.doi.org/10.1002/j.1460-2075.1994.tb06236.x.
Full textReinders, Marie G., Antonius F. van Hout, Betûl Cosgun, Aimée D. Paulussen, Edward M. Leter, Peter M. Steijlen, Klara Mosterd, Michel van Geel, and Johan J. Gille. "New mutations and an updated database for the patched-1 (PTCH1 ) gene." Molecular Genetics & Genomic Medicine 6, no. 3 (March 25, 2018): 409–15. http://dx.doi.org/10.1002/mgg3.380.
Full textBale, Sherri J., Roni T. Falk, and Geraldine R. Rogers. "Patching Together the Genetics of Gorlin Syndrome." Journal of Cutaneous Medicine and Surgery 3, no. 1 (July 1998): 31–34. http://dx.doi.org/10.1177/120347549800300109.
Full textJohnson, R. L., A. L. Rothman, J. Xie, L. V. Goodrich, J. W. Bare, J. M. Bonifas, A. G. Quinn, et al. "Human Homolog of patched, a Candidate Gene for the Basal Cell Nevus Syndrome." Science 272, no. 5268 (June 14, 1996): 1668–71. http://dx.doi.org/10.1126/science.272.5268.1668.
Full textPritchard, Joel I., and James M. Olson. "Methylation of PTCH1, the Patched-1 gene, in a panel of primary medulloblastomas." Cancer Genetics and Cytogenetics 180, no. 1 (January 2008): 47–50. http://dx.doi.org/10.1016/j.cancergencyto.2007.09.008.
Full textFan, Jun, Hiroto Akabane, Xuehai Zheng, Xuan Zhou, Li Zhang, Qiang Liu, Yong-Lian Zhang, Jing Yang, and Guo-Zhang Zhu. "Male germ cell-specific expression of a novel Patched-domain containing gene Ptchd3." Biochemical and Biophysical Research Communications 363, no. 3 (November 2007): 757–61. http://dx.doi.org/10.1016/j.bbrc.2007.09.047.
Full textHooper, Joan E., and Matthew P. Scott. "The Drosophila patched gene encodes a putative membrane protein required for segmental patterning." Cell 59, no. 4 (November 1989): 751–65. http://dx.doi.org/10.1016/0092-8674(89)90021-4.
Full textBarreto, D. C., A. E. Bale, L. De Marco, and R. S. Gomez. "Immunolocalization of PTCH Protein in Odontogenic Cysts and Tumors." Journal of Dental Research 81, no. 11 (November 2002): 757–60. http://dx.doi.org/10.1177/0810757.
Full textBokor, P., and S. DiNardo. "The roles of hedgehog, wingless and lines in patterning the dorsal epidermis in Drosophila." Development 122, no. 4 (April 1, 1996): 1083–92. http://dx.doi.org/10.1242/dev.122.4.1083.
Full textBrailey, L. L., T. Davis, S. E. Kolker, T. C. Murry, D. Thomas, A. E. Bale, and S. M. Ruhoy. "Congenital linear unilateral basal cell nevus: a case report with patched gene molecular studies." Journal of Cutaneous Pathology 34, no. 1 (January 2007): 65–70. http://dx.doi.org/10.1111/j.1600-0560.2006.00580.x.
Full textDean, Michael. "Towards a unified model of tumor suppression: lessons learned from the human patched gene." Biochimica et Biophysica Acta (BBA) - Reviews on Cancer 1332, no. 2 (April 1997): M43—M52. http://dx.doi.org/10.1016/s0304-419x(96)00043-1.
Full textKagey, Jacob D., Jordan A. Brown, and Kenneth H. Moberg. "Regulation of Yorkie activity in Drosophila imaginal discs by the Hedgehog receptor gene patched." Mechanisms of Development 129, no. 9-12 (September 2012): 339–49. http://dx.doi.org/10.1016/j.mod.2012.05.007.
Full textMaesawa, Chihaya, Gen Tamura, Takeshi Iwaya, Satoshi Ogasawara, Kaoru Ishida, Nobuhiro Sato, Satoshi Nishizuka, et al. "Mutations in the human homologue of theDrosophila patched gene in esophageal squamous cell carcinoma." Genes, Chromosomes and Cancer 21, no. 3 (March 1998): 276–79. http://dx.doi.org/10.1002/(sici)1098-2264(199803)21:3<276::aid-gcc15>3.0.co;2-n.
Full textMatos, Jefferson David Melo de, Leonardo Jiro Nomura Nakano, Pedro Jacy Santos Diamantino, Guilherme da Rocha Scalzer Lopes, Marco Antonio Bottino, John Eversong Lucena de Vasconcelos, Nathália de Carvalho Ramos, and Valdir Cabral Andrade. "Gorlin-Goltz syndrome: systemic and maxillofacial characteristics." ARCHIVES OF HEALTH INVESTIGATION 10, no. 1 (October 22, 2020): 49–54. http://dx.doi.org/10.21270/archi.v10i1.4853.
Full textMatos, Jefferson David Melo de, Leonardo Jiro Nomura Nakano, Pedro Jacy Santos Diamantino, Guilherme da Rocha Scalzer Lopes, Marco Antonio Bottino, John Eversong Lucena de Vasconcelos, Nathália de Carvalho Ramos, and Valdir Cabral Andrade. "Gorlin-Goltz syndrome: systemic and maxillofacial characteristics." ARCHIVES OF HEALTH INVESTIGATION 10, no. 1 (October 22, 2020): 49–54. http://dx.doi.org/10.21270/archi.v10i1.4853.
Full textShao, Jianguo, Ling Zhang, Jun Gao, Zhaoshen Li, and Zhirong Chen. "Aberrant Expression of PTCH (Patched Gene) and Smo (Smoothened Gene) in Human Pancreatic Cancerous Tissues and Its Association With Hyperglycemia." Pancreas 33, no. 1 (July 2006): 38–44. http://dx.doi.org/10.1097/01.mpa.0000222319.59360.21.
Full textLaimer, M., K. Önder, P. Schlager, C. M. Lanschuetzer, M. Emberger, S. Selhofer, H. Hintner, and J. W. Bauer. "Nonsense-associated altered splicing of the Patched gene fails to suppress carcinogenesis in Gorlin syndrome." British Journal of Dermatology 159, no. 1 (July 2008): 222–27. http://dx.doi.org/10.1111/j.1365-2133.2008.08617.x.
Full textBODAK, N. "High mutation frequency of the patched gene in basal cell carcinomas from xeroderma pigmentosum patients." Journal of the European Academy of Dermatology and Venereology 11 (September 1998): S304. http://dx.doi.org/10.1016/s0926-9959(98)95747-6.
Full textBodak, N., S. Queille, M. F. Avril, B. Bouadjar, C. Drougard, A. Sarasin, and L. Daya-Grosjean. "High levels of patched gene mutations in basal-cell carcinomas from patients with xeroderma pigmentosum." Proceedings of the National Academy of Sciences 96, no. 9 (April 27, 1999): 5117–22. http://dx.doi.org/10.1073/pnas.96.9.5117.
Full textHasenpusch-Theil, Kerstin, Veronique Bataille, Jaana Laehdetie, Franz Obermayr, Julian R. Sampson, and Anna-Maria Frischauf. "Gorlin syndrome: Identification of 4 novel germ-line mutations of the human patched (PTCH) gene." Human Mutation 11, no. 6 (1998): 480. http://dx.doi.org/10.1002/(sici)1098-1004(1998)11:6<480::aid-humu9>3.0.co;2-4.
Full textGallet, A., C. Angelats, S. Kerridge, and P. P. Therond. "Cubitus interruptus-independent transduction of the Hedgehog signal in Drosophila." Development 127, no. 24 (December 15, 2000): 5509–22. http://dx.doi.org/10.1242/dev.127.24.5509.
Full textJain, Neha, Ajay K. Pillai, Nisha Mishra, MD Ishtiyak, G. V. Reddy, and Saksham Nahar. "Gorlin Goltz Syndrome: A Disease in Disguise." Clinical Research and Clinical Trials 5, no. 3 (February 25, 2022): 01–05. http://dx.doi.org/10.31579/2693-4779/080.
Full textLewis, M. T., S. Ross, P. A. Strickland, C. W. Sugnet, E. Jimenez, M. P. Scott, and C. W. Daniel. "Defects in mouse mammary gland development caused by conditional haploinsufficiency of Patched-1." Development 126, no. 22 (November 15, 1999): 5181–93. http://dx.doi.org/10.1242/dev.126.22.5181.
Full textNieuwenhuis, Erica, Jun Motoyama, Paul C. Barnfield, Yoshiaki Yoshikawa, Xiaoyun Zhang, Rong Mo, Michael A. Crackower, and Chi-chung Hui. "Mice with a Targeted Mutation of Patched2 Are Viable but Develop Alopecia and Epidermal Hyperplasia." Molecular and Cellular Biology 26, no. 17 (September 1, 2006): 6609–22. http://dx.doi.org/10.1128/mcb.00295-06.
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