Dissertations / Theses: 'Partial mediation'

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McLean, M. "A longitudinal analysis of a partial mediation model of employee engagement in a knowledge-intensive firm." Thesis, Nottingham Trent University, 2014. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.664737.

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Research interest in employee engagement (EE) has recently intensified. This thesis document (the study) adds to our understanding of EE by conceptually developing and empirically testing a partial mediation model of EE within a smaller knowledge-intensive setting. The study’s aim is to longitudinally examine whether, how and why there were changes in the level and nature of EE and in satisfaction with antecedents of engagement. Linkages between these constructs are explored. An HRM ‘black box’ is thus investigated. The case study organisation, site of the empirical work, is Integrated Environmental Solutions (IES), a world leading high-tech company which supplies software and professional services to the architecture, engineering and construction sector to aid green building design and reduce energy consumption in new and existent buildings. The research methodology in this study adopts a realist stance. Quantitative and qualitative data were gathered between 2008-2010 via three employee surveys, interviews, focus groups and company documents during a period of great market turbulence at IES. The results reveal that overall EE rose to a very high level, contrary to the general trends observed in the UK. Emotional engagement remained high and stable, while both cognitive and behavioural engagement levels significantly improved. Despite a volatile business background, it seems that the strategic company responses to survey feedback via targeted actions and HR interventions sustained (or improved) satisfaction with all antecedents of engagement, apart from that of rewards and recognition. This longitudinal study suggests that four antecedents can be described as fundamental drivers of high engagement within a knowledge-intensive firm during this difficult period: long-term strategic direction and alignment; a strong people-centric culture; job satisfaction and knowledge-sharing. There is a paucity of prior longitudinal academic study into EE, especially in a knowledge-intensive context and in a recession; this study contributes to these knowledge gaps. Further, the study offers conceptual insights into a contextualised partial linkage model of EE and an analysis of how an EE strategy can be implemented in practice. The study thereby advances the limited extant studies, directly contributing to gaps in knowledge, methodological approaches and our understanding of practice. Moreover, implications for professional practice and future research direction are explicated in the study’s conclusions.

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Carter, Devin. "Examining the Incremental Validity of Working Memory for Predicting Learning and Task Performance: A Partial Mediation Model." Thesis, Virginia Tech, 2017. http://hdl.handle.net/10919/81312.

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General intelligence (“g”) has long been used as an effective predictor of both learning and job performance. Further, other more specific cognitive abilities have not been able to consistently predict incremental variance in job knowledge and job performance beyond “g”. However, the processes associated with working memory (WM) are important for these outcomes and are not captured by our traditional tests of “g”. This study tested a partial mediation model in which working memory (WM) incrementally predicts task performance above “g” through task knowledge and through a direct effect. Participants were given measures of “g” and WM in a lab. They were then given a learning opportunity and a task that applies this newly learned knowledge in order to tests the effects of WM. Results indicate that WM explains additional variance in both task knowledge and task performance, and the partial mediation model was supported using one of the two WM tasks used.
Master of Science
General intelligence is widely used in personnel selection because it is consistent in predicting the job performance of future employees. Other cognitive abilities have also been examined to determine whether they are able to predict job performance as well as general intelligence. However, most of these other cognitive abilities have come up short. This study hypothesized that working memory (WM) is a cognitive ability that may be able to predict job performance even after controlling for general intelligence. A sample of undergraduates completed tasks that measured general intelligence and WM, and this study examined how well each measure predicted both learning and performance on a relatively novel task. Results indicated that WM was able to predict both learning and performance after controlling for general intelligence.

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Wing, Edgar H. "The relationship between therapist empathy, the working alliance, and therapy outcome a test of a partial mediation model /." Ohio : Ohio University, 2010. http://www.ohiolink.edu/etd/view.cgi?ohiou1262266810.

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Wing, Edgar H. Jr. "The Relationship between Therapist Empathy, the Working Alliance, and Therapy Outcome: A Test of a Partial Mediation Model." Ohio University / OhioLINK, 2010. http://rave.ohiolink.edu/etdc/view?acc_num=ohiou1262266810.

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Wang, Huanhuan. "Partial Mediation and Moderation Effects of Class Peer Norms on the Relations of Teacher Support with Student Aggression and Academic Engagement during Early Adolescence." Scholar Commons, 2017. http://scholarcommons.usf.edu/etd/6777.

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The purpose of this study was to examine the mediation and moderation effects of classroom peer norms (CPN) on the associations of teacher support with student engagement and aggression during sixth grade (first year of middle school). Current literature suggests that early adolescence is a critical developmental period with many changes occurring, including a peak in aggression, decreased academic engagement, increased peer influence, and decreased teacher support. Despite these challenging changes, teachers often serve as a powerful yet “invisible hand” (Farmer, Lines, & Hamm, 2011) that can influence student behaviors directly or indirectly via CPN. However, these two routes of teacher influence have rarely been examined simultaneously. The current study investigated these two routes by examining the partial mediation and moderation effects of CPN on the associations of teacher support with four student behaviors (overt and relational aggression, involved and disruptive behavior) among a diverse sample of 312 students from 32 classrooms across the fall and spring of sixth grade. Students self-reported teacher support (academic, emotional) and engagement (involved, disruptive behavior) and peer-nominated aggression (overt, relational). CPN was computed as a class average of a certain behavior (aggression or engagement). Multilevel modeling was used to test the mediation and moderation effects, considering the nested nature of the data (i.e., students nested within classrooms). Results indicated full mediation effect of CPN on the relations of fall teacher support with spring overt aggression, relational aggression, and disruptive behavior, and a moderation effect on spring involved behavior. Interestingly, the average classroom perception of teacher support showed a significant direct negative effect on relational aggression and disruptive behavior, and a direct positive effect on involved behavior, all of which became smaller and non-significant when CPN was taken into consideration (i.e., when the indirect or mediation effect was considered). In terms of the mediation effects, classes which had high levels of average perception of teacher support in the fall tended to have low disruptive behavior CPN, which was further associated with low levels of individual student disruptive behavior in the spring. The same mechanism applied to overt and relational aggression, except that the significance level of the relations of CPN with overt and relational aggression was marginal (i.e., p < .10). The moderation effect suggests that students who reported high levels of teacher support in the fall (relative to his/her classmates, regardless of the class average) tended to report high levels of involved behavior in the spring only if the fall involved behavior CPN was also high. These findings highlight the importance to investigate both teacher and peer influence within a classroom in order to better understand student behaviors during the first year of middle school. Theoretical and practical implications are discussed, as well as limitations and future directions.

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Rakic, Ruzica. "Essays in Microeconomics." Doctoral thesis, Humboldt-Universität zu Berlin, 2017. http://dx.doi.org/10.18452/18080.

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Diese Dissertation besteht aus drei unabhängigen Kapiteln über mikroökonomische Themen. Die ersten beiden Kapitel befassen sich mit Themen der Industriökonomie und Wettbewerbstheorie, wohingegen das dritte Kapitel Fragestellungen von Cheap Talk Spielen untersucht. Kapitel 1 untersucht die Folgen, die sich aus einer partiellen Akquisition zwischen Wettbewerbern ergeben. Kapitel 2 analysiert die Auswirkungen einer Forschungs-und Entwicklungs (FuE)- Kooperation auf die Investitionsanreize in einem Markt, in dem eine Mehrproduktunternehmer mit einem Einzelproduktuntfirma konkurriert. Kapitel 3 untersucht die Funktion der Mediation zur Erleichterung der Kommunikation mit privaten Informationen.
This dissertation consists of three independent chapters in the field of microeconomics. The first two chapters are concerned with topics of industrial organization and competition policy, whereas the third chapter addresses some problems in cheap talk games. Chapter 1 studies anti-competitive issues that arise from partial acquisition between competitors. Chapter 2 analyzes the effects of cooperation on R&D investment incentives in a market where a multi-product firm competes with a single-product firm. The third chapter examines the role of mediation in facilitating communication with private information.

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Wu, MeiMei. "Investigating the adoption of banking services delivered over remote channels : the case of Chinese Internet banking customers." Thesis, Loughborough University, 2012. https://dspace.lboro.ac.uk/2134/9387.

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Customers adoption of Internet banking has become a widely-researched topic, although it is fair to state that some research gaps still exist. This research aims to fill some of the research gaps by examining the factors that determine the relevant behaviour of three different categories of Internet banking customers in China (i.e. current users, non-users, and discontinued users), and by developing two conceptual models that are derived from different, but complementary, theoretical approaches. The Decision Making Model and the Service and Relationship Evaluation Model are developed in this research. The Decision Making Model is grounded in the technology acceptance model (TAM) and it incorporates an additional construct of perceived value of using Internet banking. Additionally, the Service and Relationship Evaluation Model is derived from the service quality evaluation and relationship quality evaluation literature. Unlike in most other Internet banking adoption studies, these two conceptual models are used complementarily to deliver a comprehensive understanding of customers Internet banking adoption in China. The models are tested using a sample of 614 Chinese Internet banking customers collected via mall-intercept personal interviews based on questionnaires. Partial Least Square (PLS) path modelling and mediation analysis are applied to test the hypotheses advanced in the two models. The key findings of this research show that perceived value is a major factor for explaining customers Internet banking adoption, thus indicating to the banks that they should reduce costs associated with using Internet banking while providing more (perceived) benefits to customers; the importance of incorporating perceived value in Internet banking adoption model(s) is also demonstrated. The findings also confirm that perceived usefulness and perceived ease of use are important factors that determine the adoption of Internet banking by all categories of customers. Current users and non-users perceptions of their behavioural control over using Internet banking contribute to their adoption of Internet banking, and such control perceptions are shaped by self-efficacy, perceived government support and technological support. Additionally, it is demonstrated that both current users and discontinued users perceived value and perceived service quality of Internet banking have positive associations with their satisfaction with Internet banking, which lead to their Internet banking adoption. Moreover, the findings reveal that current users are more likely to continue with Internet banking if they are affectively committed to their banks; they are less likely to continue with Internet banking if they are calculatively committed to their banks due to the costs associated with leaving the banks. These therefore indicate the importance of establishing high-quality customer-bank relationships and placing less strict switching cost barriers that impose less pressure on their existing customers. This research contributes to the Internet banking adoption literature by (i) identifying the important category of Internet banking discontinued users, apart from current users and non-users; and (ii) using two complementary conceptual models, which are grounded in different theoretical streams, to investigate the relevant adoption behaviour of all three categories of Internet banking customers. It hence delivers a comprehensive understanding of personal customers adoption of Internet banking in China.

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Nolte, Sandra, and sandra nolte@mh org au. "Approaches to the measurement of outcomes of chronic disease self-management interventions using a self-report inventory." RMIT University. Global Studies, Social Science & Planning, 2008. http://adt.lib.rmit.edu.au/adt/public/adt-VIT20080822.151606.

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Background Health education programs that are aimed at improving individuals' skills to self-manage are increasingly recognised as a critical component of chronic disease management. Despite the apparent need for such interventions, current studies show inconsistent results regarding program effectiveness, with meta-analyses indicating only marginal effects for some disease groups. A closer examination of these studies however suggests that the magnitude and inconsistency of the findings may be related to the types of outcomes that were assessed rather than specific disease groups. Where self-report measures were used, results tended to be smaller and inconsistent. It is therefore possible that current studies do not adequately reflect program effects because self-report outcomes have a high risk to be confounded by a range of potential biases. Objective The aim of this thesis was to identify and quantify the potential influence of biases in the measurement of change in chronic disease self-management interventions using self-report. Methods The research design targeted the processes that individuals undergo when filling out questionnaires and whether this has an influence on their self-report outcomes. This was achieved by developing a three-group research design. The Health Education Impact Questionnaire (heiQ) was used to collect outcomes data. While pretest questionnaires were identical across groups, three questionnaire versions were randomly distributed at posttest. One of the groups filled out traditional posttest questions (n=331), whereas the other two groups were asked to provide data in addition to posttest questions, with one group providing transition questions (n=304) and one providing retrospective pretest data (n=314). Resulting datasets were further examined for possible confounding effects through response shift and social desirability bias. Through the random allocation of the heiQs it was ensured that data were not influenced by potential intra-group effects. Results The thesis revealed that the design of the posttest questionnaire significantly influenced people's ratings of their posttest levels. In particular, when participants were asked to provide ratings of their retrospective pretest levels in addition to their posttest levels, the latter scores were significantly higher than those of participants who did not perform this additional task. Subsequent analyses however suggested that these differences could neither be explained by response shift nor by social desirability bias. Conclusions This research has provided important insight into the measurement of outcomes of chronic disease self-management interventions. While the threat to the validity of traditional pretest-posttest data due to confounding effects through response shift and social desirability biases could not be supported, the thesis has highlighted that the cognitive task that subjects are asked to perform when providing data at posttest significantly influenced their self-reported outcomes. Given that previous research has predominantly focused on other aspects of validity - such as applying control group designs to circumvent common threats to internal and external validity - this study suggests that more attention must be paid to the design of questionnaires. The thesis concludes that further research, in particular into the influence of cognitive tasks on obtained scores, is important to improve the interpretation of self-report outcomes data derived from participants of self-management interventions.

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Mattei, Laetitia. "La responsabilité sociétale des entreprises et la médiation." Thesis, Paris 9, 2012. http://www.theses.fr/2012PA090038/document.

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Les crises actuelles, sous leurs multiples aspects, mettent en lumière la responsabilité des entreprises dans notre société, bousculant ainsi l'un des dogmes néolibéraux résumé par la célèbre formule de Milton Friedman (1970) : « La responsabilité sociétale de l’entreprise est d’accroître ses profits». C’est en réaction à ces crises et grâce au rôle actif de la société civile qui condamne désormais certaines pratiques, que le concept de responsabilité sociétale des entreprises (ci-après RSE) a émergé. L’enjeu est donc, aujourd’hui, de mettre en place un marché responsable entre l’entreprise et ses parties prenantes. Le législateur, par la loi Grenelle I, dispose que la médiation sera un des outils de mise en oeuvre de la RSE. Il en appelle donc au développement du droit processuel qu’est la médiation pour mettre en oeuvre ce droit substantiel qu’est la RSE. La médiation, à la fois préventive et curative, est donc un outil de mise en oeuvre de la RSE. Le couple RSE et médiation permet ainsi de combiner efficacité économique, respect social,sociétal et environnemental
Current multifaceted crises bring to light the importance of corporate responsibility in our society, thereby challenging a neoliberal tenet summarized by Milton Friedmand’s famous saying (1970): “The social responsibility of business is to increase its profits”.It is in response to these crises and thanks to the active role played by civil society who now condemns certain practices that the concept of corporate social responsibility (“CSR”) has emerged.Today’s challenge is thus to put in place a responsible marketplace between the company and its stakeholders.In the so-called Grenelle I Law, the French legislator specifies that mediation should be a toolto implement CSR.He therefore advocates the development of mediation as a procedural tool to implement CSR as an integral part of substantive law.Mediation, from both a preventive and a remedial perspective, is accordingly an instrument toimplement CSR.The CSR / mediation nexus successfully combines economic efficiency and social, societal and environmental respect

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Mardumyan, Anna. "Seeking redress from third parties : the roles of the mediator in the service recovery process." Thesis, Lyon, 2018. http://www.theses.fr/2018LYSE3082.

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Lors de la gestion d’un conflit entre un client et une entreprise, le recours à un médiateur, c’est à dire à une tierce personne neutre qui porte un jugement sur la manière dont devrait être réglé le conflit, est une pratique de plus en plus répandue, notamment du fait de l’application de la Directive Européenne 2013/11. A l’aide de six études empiriques, ce travail doctoral positionne la médiation comme une démarche conciliante qui s’inscrit au sein du processus de gestion d’une réclamation client. Les clients qui se tournent vers un médiateur recherchent notamment sa neutralité. La décision émise par le médiateur, selon qu’elle est favorable ou défavorable au client, influence ses intentions de comportement envers l’entreprise (fidélité et bouche à oreille positif). La neutralité perçue du médiateur a un effet modérateur sur cette relation. Enfin, le statut du médiateur - externe ou interne à l’entreprise - modère l'impact de la décision du médiateur sur la fidélité post-médiation du client. Ces résultats encouragent les entreprises à exploiter stratégiquement la médiation afin de reconquérir leurs clients sachant que la médiation est la dernière chance que le client donne à l'entreprise pour résoudre positivement la défaillance du service
The demand for mediation, in which a neutral third party offers advice for resolving a problem, continues to increase steadily, especially in Europe, where European Directive 2013/11 grants consumers the right to access mediation to resolve disputes with sellers. With a series of six studies, this dissertation offers the first empirical demonstration that recourse to a mediator is a form of customer conciliatory behavior in a service recovery context. Customers with recourse to a mediator look specifically for its neutrality. The mediator’s perceived neutrality then has a moderating effect on the relationship between the service recovery response by the mediator and the customer’s behavioral outcomes (loyalty and positive WOM), which is further mediated by the perceived procedural justice of the mediation process. Finally, the mediation status – external or internal – moderates the effect of the outcome on customer post-mediation loyalty. These findings encourage firms to leverage mediation resources strategically to win back customers, because mediation represents the last chance that the customer gives the firm to positively resolve the service failure

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Singh, Amar M. "Expression and partial characterization of two new proteins that interact with death associated protein-3, a mitochondrial ribosome protein and positive mediator of apoptosis." [Gainesville, Fla.] : University of Florida, 2003. http://purl.fcla.edu/fcla/etd/UFE0001076.

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Morgenstern, Caroline. "Den Parteien laufen die Mitglieder davon." Doctoral thesis, Universitätsbibliothek Chemnitz, 2015. http://nbn-resolving.de/urn:nbn:de:bsz:ch1-qucosa-150550.

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Der umfangreiche Forschungsstand zum Thema Parteien weist in verschiedenen Bereichen Unklarheiten auf. So wird beispielsweise ein Zusammenhang zwischen dem Mitgliederrückgang der deutschen Parteien, gesellschaftlichen Modernisierungsprozessen und einem Funktionserfüllungsdefizit, speziell im Bereich der Vermittlungsleistung der Parteien, angenommen. Unklar hierbei sind u.a. folgende Punkte: (1) was genau unter dem Prozess der Mediation zu verstehen ist, (2) welche Modernisierungsprozesse beteiligt sind und (3) ob und wenn ja, wie sich er Mitgliederrückgang auswirkt. In der Summe führen diese ungeklärten Fragen dazu, dass letztlich auch keine verbindlichen Aussagen zum antizipierten Mediationsdefizit getroffen werden können. Explizit aus einem soziologischen Fokus heraus gibt diese Arbeiten systematisch Antworten. Im ersten Kapitel wird geklärt, was unter einer Partei im soziologischen Sinne zu verstehen ist und was die Mediationsfunktion der Partei konkret ausmacht. Im zweiten Kapitel rücken die Parteien und deren Mitglieder in den Mittelpunkt. Es geht um die Frage, welche Aufgaben von dieser Seite erfüllt werden müssen, damit die Vermittlung reibungslos stattfinden kann, d.h. im Umkehrschluss wo sich gegebenenfalls Defizite verorten lassen. Neben allgemeinen Merkmalen von Mitgliederparteien, rücken hier auch sozialstrukturelle Merkmale der Parteimitglieder sowie erste Modernisierungsprozesse in den Vordergrund. Im dritten Kapitel wird die Problematik von der anderen Seite, der Gesellschaftsseite, angegangen. Auch hier wir danach gefragt, welche konkreten Schritte für die Umsetzung der Mediationsfunktion realisiert werden müssen. Zudem werden weitere Modernisierungsprozesse betrachtet. Es wird sich im Abschlusskapitel zeigen, dass die Vermittlungsfunktion der Parteien zu keinem Zeitpunkt fehlerfrei realisiert werden konnte, sich die Problematik seit den 1980er Jahren verstärkt hat was heute dazu führt, dass unkonventionelle Gruppen und Institutionen, z.B. neue soziale Bewegungen oder NGO´s, immer stärker in den politischen Vermittlungsprozess einbezogen werden (müssen)
The extensive research on the subject parties shows ambiguities in various areas. For example a correlation between the decline in membership of the German parties, social modernization processes and functional performance deficit, special in the mediation of political parties, is assumed. Unclear in this context are inter alia the following points: (1) what exactly is meant by the process of mediation, (2) which modernization processes are involved, and (3) whether, and if so, how it affects members of decline. In sum these unresolved issues cause ultimately no binding statements can be made to the anticipated deficit mediation. Explicitly from a sociological focus publishes this work systematically answers. In the first chapter will clarify what is meant by a party in a sociological sense and what constitutes the mediation function of the party concrete. In the second chapter the parties and their members in focus. It is about the question of which tasks must be performed by this page so that the mediation can take place smoothly, a contrario where optionally can locate deficits. In addition to general characteristics of member parties socially structural features of party members and first modernization processes move in the foreground. In the third chapter the problem from the other side, the company side, addressed. Again we asked what concrete steps for the implementation of the mediation function must be implemented. In addition, further modernization processes are considered. It will show in the final chapter that the mediation function of the parties could be realized without errors at any time, the problem has intensified since the 1980s, which leads today that unconventional groups and institutions, for example new social movements and NGOs, are becoming more involved in the political process of mediation (have to)

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Hapuarachchi, John Romuald. "Work-home conflict as mediating the impact of role conflict and role overload on burnout and job satisfaction in psychiatric nurses : a test of 'partial medication spill-over' model /." Title page, contents and abstract only, 1995. http://web4.library.adelaide.edu.au/theses/09AR.PS/09ar.psh252.pdf.

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Morgenstern, Caroline. "Den Parteien laufen die Mitglieder davon: Eine soziologische Untersuchung zur Funktionsfähigkeit der deutschen Parteien vor dem Hintergrund schwindender Mitgliederbestände." Doctoral thesis, Universitätsverlag der Technischen Universität Chemnitz, 2014. https://monarch.qucosa.de/id/qucosa%3A20101.

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Der umfangreiche Forschungsstand zum Thema Parteien weist in verschiedenen Bereichen Unklarheiten auf. So wird beispielsweise ein Zusammenhang zwischen dem Mitgliederrückgang der deutschen Parteien, gesellschaftlichen Modernisierungsprozessen und einem Funktionserfüllungsdefizit, speziell im Bereich der Vermittlungsleistung der Parteien, angenommen. Unklar hierbei sind u.a. folgende Punkte: (1) was genau unter dem Prozess der Mediation zu verstehen ist, (2) welche Modernisierungsprozesse beteiligt sind und (3) ob und wenn ja, wie sich er Mitgliederrückgang auswirkt. In der Summe führen diese ungeklärten Fragen dazu, dass letztlich auch keine verbindlichen Aussagen zum antizipierten Mediationsdefizit getroffen werden können. Explizit aus einem soziologischen Fokus heraus gibt diese Arbeiten systematisch Antworten. Im ersten Kapitel wird geklärt, was unter einer Partei im soziologischen Sinne zu verstehen ist und was die Mediationsfunktion der Partei konkret ausmacht. Im zweiten Kapitel rücken die Parteien und deren Mitglieder in den Mittelpunkt. Es geht um die Frage, welche Aufgaben von dieser Seite erfüllt werden müssen, damit die Vermittlung reibungslos stattfinden kann, d.h. im Umkehrschluss wo sich gegebenenfalls Defizite verorten lassen. Neben allgemeinen Merkmalen von Mitgliederparteien, rücken hier auch sozialstrukturelle Merkmale der Parteimitglieder sowie erste Modernisierungsprozesse in den Vordergrund. Im dritten Kapitel wird die Problematik von der anderen Seite, der Gesellschaftsseite, angegangen. Auch hier wir danach gefragt, welche konkreten Schritte für die Umsetzung der Mediationsfunktion realisiert werden müssen. Zudem werden weitere Modernisierungsprozesse betrachtet. Es wird sich im Abschlusskapitel zeigen, dass die Vermittlungsfunktion der Parteien zu keinem Zeitpunkt fehlerfrei realisiert werden konnte, sich die Problematik seit den 1980er Jahren verstärkt hat was heute dazu führt, dass unkonventionelle Gruppen und Institutionen, z.B. neue soziale Bewegungen oder NGO´s, immer stärker in den politischen Vermittlungsprozess einbezogen werden (müssen).
The extensive research on the subject parties shows ambiguities in various areas. For example a correlation between the decline in membership of the German parties, social modernization processes and functional performance deficit, special in the mediation of political parties, is assumed. Unclear in this context are inter alia the following points: (1) what exactly is meant by the process of mediation, (2) which modernization processes are involved, and (3) whether, and if so, how it affects members of decline. In sum these unresolved issues cause ultimately no binding statements can be made to the anticipated deficit mediation. Explicitly from a sociological focus publishes this work systematically answers. In the first chapter will clarify what is meant by a party in a sociological sense and what constitutes the mediation function of the party concrete. In the second chapter the parties and their members in focus. It is about the question of which tasks must be performed by this page so that the mediation can take place smoothly, a contrario where optionally can locate deficits. In addition to general characteristics of member parties socially structural features of party members and first modernization processes move in the foreground. In the third chapter the problem from the other side, the company side, addressed. Again we asked what concrete steps for the implementation of the mediation function must be implemented. In addition, further modernization processes are considered. It will show in the final chapter that the mediation function of the parties could be realized without errors at any time, the problem has intensified since the 1980s, which leads today that unconventional groups and institutions, for example new social movements and NGOs, are becoming more involved in the political process of mediation (have to).

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Figueir?do, Alexsandro de Oliveira. "A f?sica brasileira na educa??o b?sica: discutindo as contribui??es de c?sar lattes para a descoberta do m?son ? a partir de uma abordagem hist?rica e conceitual." Universidade Estadual de Feira de Santana, 2017. http://tede2.uefs.br:8080/handle/tede/tede/646.

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Submitted by Verena Pereira (verenagoncalves@uefs.br) on 2018-07-11T23:13:30Z No. of bitstreams: 1 DIsserta??o Alexsandro VFA HIST?RIA DO M?SON PI .pdf: 9797951 bytes, checksum: 05cccd1dc1df86aff95c514b9ac8f4ab (MD5)
Made available in DSpace on 2018-07-11T23:13:30Z (GMT). No. of bitstreams: 1 DIsserta??o Alexsandro VFA HIST?RIA DO M?SON PI .pdf: 9797951 bytes, checksum: 05cccd1dc1df86aff95c514b9ac8f4ab (MD5) Previous issue date: 2017-08-30
Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior - CAPES
This work represents our contribution to disseminate Brazilian Physics in the classroom. It consists of a qualitative research about the insertion of topics of Particle Physics through a conceptual approach, particularly the first proposal of Yukawa for strong interaction, from the history of the discovery of the ? meson with the contributions of the brazilian scientist, C?sar Lattes. The research consisted in the elaboration, application and evaluation of a didactic sequence based on the theory of significant learning of David Ausubel
Com este estudo, pretende-se contribuir para a divulga??o da F?sica brasileira em sala de aula. Ele consiste em uma pesquisa qualitativa que trata da inser??o de t?picos de F?sica de Part?culas atrav?s de abordagem conceitual, particularmente a primeira proposta de Yukawa para intera??o forte, a partir da hist?ria da descoberta do m?son ? com as contribui??es do brasileiro C?sar Lattes. A pesquisa consistiu na elabora??o, aplica??o e avalia??o de uma sequ?ncia did?tica fundamentada na teoria de aprendizagem significativa de David Ausubel

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Derolez, Séverine. "La patrimonialisation des objets scientifiques contemporains et leurs contextes de valorisation : cas de l’accélérateur de particules Cockcroft-Walton." Thesis, Lyon, 2016. http://www.theses.fr/2016LYSE1274/document.

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Notre recherche en didactique des sciences, explore la potentialité des objets scientifiques contemporains à devenir des objets de patrimoine à travers un cas d'étude : l'accélérateur de particules Cockcroft-Walton (CW). Nous faisons l'hypothèse que la valorisation des objets scientifiques contemporains, étape importante du processus de patrimonialisation, est spécifique et nécessite une expertise particulière. Notre travail a été réalisé grâce au dispositif CIFRE, nous permettant de travailler aux côtés du musée des Confluences à Lyon, qui expose un accélérateur de particules CW dans Sociétés : le théâtre des hommes. L'Institut de Physique Nucléaire de Lyon (IPNL) possède également un appareil de ce type, qui est aujourd'hui au cœur d'un projet de valorisation. Notre analyse s'appuie sur une étude du contexte, historique, épistémologique et social, de « naissance » du premier accélérateur CW et d'une étude scientifique de l'objet. Nous avons également mené deux enquêtes, la première visant à retracer la trajectoire de l'accélérateur CW à Lyon, la seconde à retrouver l'ensemble des accélérateurs CW dans le monde. En nous appuyant sur différents travaux qui ont souligné les étapes du processus de patrimonialisation, nous avons caractérisé les spécificités du patrimoine scientifique contemporain, et recherché les traces laissées par ces caractéristiques dans la mise en exposition de l'objet. Nos résultats mettent en évidence le manque d'informations permettant l'interprétation et l'appropriation de l'accélérateur CW par un public, et nous invitent à interroger le contenu représentationnel de l'objet, véhiculé à travers d'autres contextes d'utilisation, formel ou fictionnel
Our thesis in science education explore the potentiality of contemporary scientific objects to become objects of heritage through a study case: the Cockcroft-Walton particle accelerator (CW). We call it “patrimonialisation” (the making of heritage) according to Information and Communication Sciences. We assume that the value of contemporary scientific objects, an important stage of the patrimonialisation, is specific and requires a particular expertise. Our work was realized thanks to a french financing facility, allowing us to work with Le musée des Confluences in Lyon (France), which exposes a particle accelerator CW in Societies: the human theater. The Institute of Lyon Nuclear physics (IPNL) also possesses a device of this type, who is the focus of a recognition project. sing a multidisciplinary approach, our analysis begin with a study of historical, epistemological, social and scientific context, of the first one CW. We also led two inquiries, the first one to redraw the accelerator CW trajectory in Lyon, the second to find all the accelerators CW in the world. Several studies have indeed highlighted the stages of the patrimonialisation. Relying on these studies we characterized the specificities of the contemporary scientific heritage, and looked for tracks left by these characteristics in the exhibition text (museography). Our results demonstrate the lack of information allowing the interpretation (lecture) and the appropriation of the accelerator CW by a public, and invite us to question the representational contents of the object, conveyed through other contexts of use, formal or fictional

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Hallsjö, Sven-Patrik. "Search for Dark Matter in the Upgraded High Luminosity LHC at CERN : Sensitivity of ATLAS phase II upgrade to dark matter production." Thesis, Linköpings universitet, Institutionen för fysik, kemi och biologi, 2014. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-107583.

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The LHC at CERN is now undergoing a set of upgrades to increase the center of mass energy for the colliding particles to be able to explore new physical processes. The focus of this thesis lies on the so called phase II upgrade which will preliminarily be completed in 2023. After the upgrade the LHC will be able to accelerate proton beams to such a velocity thateach proton has a center of mass energy of 14 TeV. One disadvantage of the upgrade is that it will be harder for the atlas detector to isolate unique particle collisions since more and more collisions will occur simultaneously, so called pile-up. For 14 TeV there does not exist a full simulation of the atlas detector. This thesis instead uses data from Monte Carlo simulations for the particle collisions and then uses so called smearing functions to emulate the detector responses. This thesis focuses on how a mono-jet analysis looking for different wimp models of dark matter will be affected by this increase in pile-up rate. The signal models which are in focus are those which try to explain dark matter without adding new theories to the standard model or QFT, such as the effective theory D5 operator and light vector mediator models. The exclusion limits set for the D5 operators mass suppression scale at 14 TeV and 1000 fb-1are 2-3 times better than previous results at 8 TeV and 10 fb-1. For the first time limits have been set on which vector mediator mass models can be excluded at 14 TeV.

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Beresford, Lydia Audrey. "Searches for dijet resonances using √s = 13 TeV proton-proton collision data recorded by the ATLAS detector at the Large Hadron Collider." Thesis, University of Oxford, 2017. http://ora.ox.ac.uk/objects/uuid:c516b04b-2763-487a-a633-6c506cec93ad.

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This thesis presents three searches for new resonances in dijet invariant mass spectra. The spectra are produced using √s = 13 TeV proton-proton collision data recorded by the ATLAS detector. New dijet resonances are searched for in the mass range 200 GeV to 6.9 TeV in mass. Heavy new resonances, with masses above 1.1 TeV, are targeted by a high mass dijet search. Light new resonances, with masses down to 200 GeV, are searched for in dijet events with an associated high momentum object (a photon or a jet) arising from initial state radiation. The associated object is used to efficiently trigger the recording of low mass dijet events. All of the analyses presented in this thesis search for an excess of events, localised in mass, above a data-derived estimate of the smoothly falling QCD background. In each search no evidence for new resonances is observed, and the data are used to set 95% C.L. limits on the production cross-section times acceptance times branching ratio for model-independent Gaussian resonance shapes, as well as benchmark signals. One particular benchmark signal which is considered in all of the searches is an axial-vector Z' dark matter mediator model whose parameter space is reduced due to the results presented in this thesis.

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Kylesten, Celia, and Conny Malmgren. "Ansvarsförsäkring vid försäkringsförmedling;ansvarsförsäkringens räckvidd och betydelsen av partsvilja." Thesis, Linköpings universitet, Filosofiska fakulteten, 2020. http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-172004.

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Vid försäkringsförmedling skyddas försäkringstagare av försäkringsgivares obligatoriska ansvarsförsäkring. Det innebär att försäkringstagare har möjlighet att få ersättning via ansvarsförsäkring i vissa fall när försäkringsförmedlare anses skadeståndsskyldiga. Omfattningen av begreppet försäkringsförmedling och tolkningsmetoden vid utredandet huruvida något skall omfattas av ansvarsförsäkring har förefallit oklart, varför det utreds i uppsatsen. Syftet med uppsatsen är dels att analysera potentiella konsekvenser av utfallet i det s.k. Connecta-målet (NJA 2019 s. 638 del II), dels att utreda försäkringsförmedlares ansvarsräckvidd med särskilt fokus på när ansvarsförsäkring, till vilka försäkringsförmedlare är bundna, skall anses gälla. I NJA 2019 s. 638 del I och II begärdes förhandsavgörande från EU-domstolen vilket sedan behandlades i HD. Av målen framkommer att en försäkringsförmedlares avsikt och en försäkringstagares subjektiva uppfattning inte skall tillmätas någon betydelse vid avgörande av huruvida ett förfarande skall anses vara försäkringsförmedling och således täckas av den obligatoriska ansvarsförsäkringen. Det framkommer även att ett faktiskt avtal inte krävs för att förberedelse inför försäkringsavtal skall kunna ske. I uppsatsen utreds vilka potentiella konsekvenser utlåtanden i NJA 2019 s. 638 del II, i fråga om parternas uppfattning och avsikt, kan medföra. Detta görs bland annat med bakgrund av Jessika van der Sluijs artiklar om Connecta-målet i tidskriften Ny Juridik. Även omfattningen av begreppet försäkringsförmedling utreds med utgångspunkt i NJA 2019 s. 638 del I och II. Till bakgrund för analysen behandlas även bland annat EU-direktiv och svensk lagstiftning samt föreskrifter som ger ledning för analysen.Avslutningsvis dras slutsatser angående uppsatsens frågeställningar för att uppfylla uppsatsens syfte. Framförs görs bland annat uppfattningen att utgången i NJA 2019 s. 638, klargjort omfattningen av begreppet försäkringsförmedling och tydliggjort att det objektiva underlaget skall vara avgörande framför parternas avsikt samt subjektiva uppfattning. Således utvidgas ansvaret för försäkringsförmedlare och även vad som anses omfattas av en obligatorisk ansvarsförsäkring.

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Houedjissin, Mededode. "Les victimes devant les juridictions pénales internationales." Phd thesis, Université de Grenoble, 2011. http://tel.archives-ouvertes.fr/tel-00628543.

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La position des victimes sur la scène pénale internationale a considérablement évolué depuis la mise en place des tous premiers tribunaux militaires internationaux en 1945. Même si les victimes n'ont pas, à proprement parler, le statut de " partie " au procès pénal international, leur participation au procès est désormais une garantie, avec des droits substantiels. L'étendue de ces droits, aux différentes phases de la procédure, clarifie la manière dont les dispositions correspondantes du droit positif international sont interprétées par le juge pénal international. La fonction des victimes tient, dans un premier temps, davantage à " corroborer l'action publique " internationale qu'à pouvoir déclencher par elles-mêmes cette action destinée à établir la culpabilité ou non des personnes, objets du procès pénal international. Leur rôle se renforce finalement au moment de la présentation, par la voie subsidiaire d'intervention, des réclamations civiles, et plus largement de la recherche d'une pleine satisfaction ; moment au cours duquel les victimes deviennent de véritables " parties civiles " disposant pleinement de la capacité juridique internationale pour faire valoir leur droit. Ainsi, fort de leur action, les victimes paraissent dans une posture " double ", vindicative (répression) et réparatrice (indemnisation). L'objectif, visé et atteint, était donc de montrer quelle était aujourd'hui la place des victimes devant les juridictions pénales internationales.

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Ba, Oumar. "La politisation des partis à caractère ethnique dans les pays postcommunistes d’Europe Centrale et Orientale : une comparaison des trajectoires de la Bulgarie, la Serbie, le Monténégro et le Kosovo." Thesis, Bordeaux 4, 2013. http://www.theses.fr/2013BOR40052.

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Les révolutions de l’Est ont induit la fragmentation des Etats qui s’est accompagnée, sur le plan interne par une renaissance des partis ethniques ; ce qui ne va pas sans poser de problèmes à la démocratie politique. Les transitions et a fortiori les consolidations démocratiques font émerger un double phénomène d’interaction entre les acteurs et le système, dans la recherche d’un nouvel équilibre. Les partis ethniques se politisent alors que le système s’ouvre à l’acteur ethnique. On assiste donc à un réajustement évolutif du système devant la nouvelle donne. Le système s’ouvre aux nouvelles demandes à caractère ethnique de différentes façons et à différents degrés : entre la légalisation et la tolérance. Côté acteurs, les partis ethniques rentrent progressivement dans le jeu politique ; de différentes façons et à différents degrés. Dans notre champ problématique les relations interactives se déploient entre acteurs multi-niveaux (partis-Etats) et dans les divers champs (politique, sociétal et juridique). Leurs connexions sont croisées entre l’espace étatique et internationale, public et civil, politique et sociétal ; avec les Etats d’accueil ou d’origine, mais aussi, les Etats-tiers. Ils sont à velléités indépendantistes ou simplement des lobbies politiques. Nous avons essayé de mettre en lumière les principaux aspects de la complexité de la question ethnique dans les jeunes démocraties politiques ‘‘en consolidation’’. La problématique ethnique des PECO peut-elle nous aider à compléter en actualisant certaines visions généralistes des sciences politiques ? Les acteurs impliqués sont ainsi invités à éviter les pièges des nationalismes perçus comme ‘‘mesquins’’, voire ‘‘chaotiques’’ tout en servant la cause d’une plus souple intégration politique alias la ‘‘paix démocratique’’
The revolutions of Eastern induced fragmentation of States were accompanied internally by a revival of ethnic parties, which is not without its problems in political democracy. Transitions and even more democratic consolidation are emerging a double phenomenon of interaction between actors and the system in search of a new equilibrium. Ethnic parties then politicize the system opens the ethnic actor. We are witnessing an evolutionary adjustment of the system to the new situation. The system opens to the new demands ethnic ways and to different degrees: between legalization and tolerance. Side actors, are gradually returning ethnic parties in the political game, in different ways and to different degrees. In our problem the field deploy interactive relationships between multi-level actors (parties-States) and in the various fields (political, societal and legal). Their connections are crossed between the State and international space, public and civil, political and social, with host countries or origin, but also the third States. They are separatist ambitions or simply political lobbies. We tried to highlight the main aspects of the complexity of the ethnic issue in young democracies political '' in consolidation ''. The ethnic problem of CEEC can help us to complete updating some general visions of political science? The actors involved are invited to avoid the pitfalls of nationalism perceived as '' petty '' or '' chaotic '' while serving the cause of a more flexible policy integration to the ‘‘democratic peace’’

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Khambaty, Tasneem. "Is Periodontal Disease a Partial Mediator of the Association Between Depressive Symptoms And Cardiovascular Disease?" Thesis, 2012. http://hdl.handle.net/1805/2927.

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Indiana University-Purdue University Indianapolis (IUPUI)
Epidemiological studies suggest that depression may be an independent risk factor for cardiovascular disease (CVD). Although several possible mediators of this association have been proposed, the precise mechanisms are yet unknown. Accordingly, we examined periodontal disease as a novel mediator of the depression-CVD association, given its separate links with both depression and CVD. Data from the National Health and Nutrition Examination Survey (NHANES) I and its Epidemiologic Follow-up Study (NHEFS) were analyzed. Participants were 3,346 individuals aged 25-74 years free of CVD at baseline (53% female, 16% non-white). Depression was assessed by the, depressed mood subscale of the General Well-Being Schedule Based on the Russell Periodontal Index, periodontal disease (43%) was defined as the presence of four or more periodontal pockets identified by a licensed dentist during an examination. The primary outcome was incident CVD (n=727, 22%), defined as nonfatal or fatal coronary artery disease or cerebrovascular disease, identified during the follow-up period by interviews and death certificate records. All analyses were adjusted for demographic and cardiovascular risk factors. Logistic regression analyses revealed no association between the GWBS depressed mood score and periodontal disease (OR=1.05, 95% CI: 0.96-1.14, p=.24). Cox proportional hazard models revealed that both periodontal disease (HR=1.24, 95% CI: 1.06-1.46, p=.009) and depressed mood (HR=1.08, 95% CI: 1.01-1.17, p=.03) were significant predictors of incident CVD. However, Sobel analyses found that periodontal disease was not a partial mediator of the depressed mood-incident CVD association (t=1.01, p=.31). Overall, these mediation results suggest that (a) both periodontal disease and depressed mood are independent predictors of incident CVD and that (b) the effect of depressive symptoms on incident CVD is not mediated by periodontal disease.

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Chu, Yiyi. "Bayesian mediation analysis for partially clustered designs." 2013. http://hdl.handle.net/2152/22571.

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Partially clustered design is common in medicine, social sciences, intervention and psychological research. With some participants clustered and others not, the structure of partially clustering data is not parallel. Despite its common occurrence in practice, limited attention has been given regarding the evaluation of intervention effects in partially clustered data. Mediation analysis is used to identify the mechanism underlying the relationship between an independent variable and a dependent variable via a mediator variable. While most of the literature is focused on conventional frequentist mediation models, no research has studied a Bayesian mediation model in the context of a partially clustered design yet. Therefore, the primary objectives of this paper are to address conceptual considerations in estimating the mediation effects in the partially clustered randomized designs, and to examine the performances of the proposed model using both simulated data and real data from the Early Childhood Longitudinal Study, Kindergarten Class of 1998-99 (ECLS-K). A small-scale simulation study was also conducted and the results indicate that under large sample sizes, negligible relative parameter bias was found in the Bayesian estimates of the indirect effects and of covariance between the components of the indirect effect. Coverage rates for the 95% credible interval for these two estimates were found to be close to the nominal level. These results supported use of the proposed Bayesian model for partially clustered mediation in conditions when the sample size is moderately large.
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Landmann, Dirk Hauke. "Capacity development of small-scale farmers in developing countries: Analysis of preferences and the role of information and communication technologies." Doctoral thesis, 2018. http://hdl.handle.net/11858/00-1735-0000-002E-E505-2.

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Chen, Ruei-Yu, and 陳睿宇. "The Relationship between Social Conformity and Voice Behavior-The Partially Mediating Effect of Psychological Safety." Thesis, 2016. http://ndltd.ncl.edu.tw/handle/7aqyku.

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碩士
元智大學
經營管理碩士班(領導學程)
104
Nowadays, the atmosphere of democracy has become a trend. According to Schaffer’s introduction about American’s language use about “democracy”, it was defined as “members’ mass participation and free elections in the decision-making process”. However, though we are in such a democratic society, it’s still common to see people reluctant to say their own ideas or suggestions. What’s the factor behind? There’s not much research which indicates the relationship between social conformity and voice behavior in the past. In this research, we assumed that when people’s social conformity is high, they felt more threatened; so they are less willing to express their ideas. By this study, we found that how to create better voice behavior under the influences of social conformity and psychological safety in order to protect our rights by expressing different points of view.

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Bent, Eileen Katherine. "An Examination of Hypothalamic-Pituitary-Adrenal Axis Reactivity as a Partial Mediator of the Relation Between Trauma and Self-injurious Behavior." 2010. https://scholarworks.umass.edu/open_access_dissertations/322.

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Past work has linked self-injurious behavior (SIB) to a history of traumatic experiences and to problems regulating affect. While this affect dysregulation is conceptualized as occurring at a biological (as well as a behavioral) level, relatively little is known about the biological mechanisms involved. The current study explored whether reactivity of the hypothalamic-pituitary-adrenal (HPA) axis to an interpersonal stressor mediated the relation between trauma and SIB in a sample of 178 18-21 year-old heterosexual dating couples. As predicted, both trauma experience and symptoms positively predicted SIB. While the mediating model was not supported, SIB was associated with an HPA axis response marked by heightened reactivity to interpersonal stress within the context of lower cortisol levels. Trauma symptoms and experience interacted with adult attachment security to predict HPA axis response in different ways for men and women, a compelling set of findings suggesting the importance of contextual factors in the study of trauma and HPA axis function. Future directions for the study of trauma, HPA axis reactivity, and SIB are discussed.

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Bent, Eileen. "An examination of hypothalamic-pituitary-adrenal axis reactivity as a partial mediator of the relation between trauma and self-injurious behavior." 2010. https://scholarworks.umass.edu/dissertations/AAI3427499.

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Past work has linked self-injurious behavior (SIB) to a history of traumatic experiences and to problems regulating affect. While this affect dysregulation is conceptualized as occurring at a biological (as well as a behavioral) level, relatively little is known about the biological mechanisms involved. The current study explored whether reactivity of the hypothalamic-pituitary-adrenal (HPA) axis to an interpersonal stressor mediated the relation between trauma and SIB in a sample of 178 18-21 year-old heterosexual dating couples. As predicted, both trauma experience and symptoms positively predicted SIB. While the mediating model was not supported, SIB was associated with an HPA axis response marked by heightened reactivity to interpersonal stress within the context of lower cortisol levels. Trauma symptoms and experience interacted with adult attachment security to predict HPA axis response in different ways for men and women, a compelling set of findings suggesting the importance of contextual factors in the study of trauma and HPA axis function. Future directions for the study of trauma, HPA axis reactivity, and SIB are discussed.

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Nagai, Althea K. "Electoral laws and party organization as mediating structures between voters' preferences and party policy stands an analysis and interpretation of Japan's Liberal Democratic Party /." 1986. http://catalog.hathitrust.org/api/volumes/oclc/32492991.html.

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Samsell, Molly. "Camera and image : mediator and interface : a thesis presented in partial fulfilment of the requirements for the Master of Fine Arts at Massey University, Wellington, Aotearoa New Zealand." 2009. http://hdl.handle.net/10179/1020.

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How can art, specifically photography, illustrate the limitations of vision? What do those limits reveal about perception and knowing? To explore these questions two distinct mechanisms need to be discussed in relation to creative practice, Paul Virilio’s augmenting lens that forever changes the photographer’s perception and the image acting as an object for both Maurice Merleau-Ponty’s embodied experience and Jean Baudrillard’s simulacrum. The photographic image becomes an index by exposing the relationship between photographer and image. The camera is a tool, to Virilio a prosthetic eye, which immediately affects the photographer’s perception of her environment. The phenomenal world is the one that is photographed, a subjective experience. The tension between surface and reality, image and object, removes the photographic experience from an experience of the real. The making of the image closely parallels the act of viewing the image. A dual experience emerges from the photograph, the creation of the image and the viewer’s act of reading, inferring. An image, as an index, is open to multiple interpretations, placing equal weight on each participant, viewer, and creator, so that there is no hierarchy of interpretation, experience, or meaning. In this thesis these questions are explored in relation to a creative practice embedding theory with process and outcome.

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Yang-Snyder, Julia Ann. "Anatomical and developmental patterns of interleukin-2 gene expression in the mouse: analysis of IL-2 expressing cells and partial characterization of interactions involved in mediating IL-2 gene expression in vivo." Thesis, 1994. https://thesis.library.caltech.edu/7731/2/yang-snyder%201994.pdf.

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Interleukin-2 (IL-2) is an important mediator in the vertebrate immune system. IL-2 is a potent growth factor that mature T lymphocytes use as a proliferation signal and the production of IL-2 is crucial for the clonal expansion of antigen-specific T cells in the primary immune response. IL-2 driven proliferation is dependent on the interaction of the lymphokine with its cognate multichain receptor. IL-2 expression is induced only upon stimulation and transcriptional activation of the IL-2 gene relies extensively on the coordinate interaction of numerous inducible and constitutive trans-acting factors. Over the past several years, thousands of papers have been published regarding molecular and cellular aspects of IL-2 gene expression and IL-2 function. The vast majority of these reports describe work that has been carried out in vitro. However, considerably less is known about control of IL-2 gene expression and IL-2 function in vivo.

To gain new insight into the regulation of IL-2 gene expression in vivo, anatomical and developmental patterns of IL-2 gene expression in the mouse were established by employing in situ hybridization and immunohistochemical staining methodologies to tissue sections generated from normal mice and mutant animals in which T -cell development was perturbed. Results from these studies revealed several interesting aspects of IL-2 gene expression, such as (1) induction of IL-2 gene expression and protein synthesis in the thymus, the primary site of T-cell development in the body, (2) cell-type specificity of IL-2 gene expression in vivo, (3) participation of IL-2 in the extrathymic expansion of mature T cells in particular tissues, independent of an acute immune response to foreign antigen, (4) involvement of IL-2 in maintaining immunologic balance in the mucosal immune system, and (5) potential function of IL-2 in early events associated with hematopoiesis.

Extensive analysis of IL-2 mRNA accumulation and protein production in the murine thymus at various stages of development established the existence of two classes of intrathymic IL-2 producing cells. One class of intrathymic IL-2 producers was found exclusively in the fetal thymus. Cells belonging to this subset were restricted to the outermost region of the thymus. IL-2 expression in the fetal thymus was highly transient; a dramatic peak ofiL-2 mRNA accumulation was identified at day 14.5 of gestation and maximal IL-2 protein production was observed 12 hours later, after which both IL-2 mRNA and protein levels rapidly decreased. Significantly, the presence of IL-2 expressing cells in the day 14-15 fetal thymus was not contingent on the generation of T-cell receptor (TcR) positive cells. The second class of IL-2 producing cells was also detectable in the fetal thymus (cells found in this class represented a minority subset of IL-2 producers in the fetal thymus) but persist in the thymus during later stages of development and after birth. Intrathymic IL-2 producers in postnatal animals were located in the subcapsular region and cortex, indicating that these cells reside in the same areas where immature T cells are consigned. The frequency of IL-2 expressing cells in the postnatal thymus was extremely low, indicating that induction of IL-2 expression and protein synthesis are indicative of a rare activation event. Unlike the fetal class of intrathymic IL-2 producers, the presence of IL-2 producing cells in the postnatal thymus was dependent on to the generation of TcR+ cells. Subsequent examination of intrathymic IL-2 production in mutant postnatal mice unable to produce either αβ or γδ T cells showed that postnatal IL-2 producers in the thymus belong to both αβ and γδ lineages. Additionally, further studies indicated that IL-2 synthesis by immature αβ -T cells depends on the expression of bonafide TcR αβ-heterodimers. Taken altogether, IL-2 production in the postnatal thymus relies on the generation of αβ or γδ-TcR^+ cells and induction of IL-2 protein synthesis can be linked to an activation event mediated via the TcR.

With regard to tissue specificity of IL-2 gene expression in vivo, analysis of whole body sections obtained from normal neonatal mouse pups by in situ hybridization demonstrated that IL-2 mRNA^+ cells were found in both lymphoid and nonlymphoid tissues with which T cells are associated, such as the thymus (as described above), dermis and gut. Tissues devoid of IL-2 mRNA^+ cells included brain, heart, lung, liver, stomach, spine, spinal cord, kidney, and bladder. Additional analysis of isolated tissues taken from older animals revealed that IL-2 expression was undetectable in bone marrow and in nonactivated spleen and lymph nodes. Thus, it appears that extrathymic IL-2 expressing cells in nonimmunologically challenged animals are relegated to particular epidermal and epithelial tissues in which characterized subsets of T cells reside and thatinduction of IL-2 gene expression associated with these tissues may be a result of T-cell activation therein.

Based on the neonatal in situ hybridization results, a detailed investigation into possible induction of IL-2 expression resulting in IL-2 protein synthesis in the skin and gut revealed that IL-2 expression is induced in the epidermis and intestine and IL-2 protein is available to drive cell proliferation of resident cells and/or participate in immune function in these tissues. Pertaining to IL-2 expression in the skin, maximal IL-2 mRNA accumulation and protein production were observed when resident Vγ_3^+ T-cell populations were expanding. At this age, both IL-2 mRNA^+ cells and IL-2 protein production were intimately associated with hair follicles. Likewise, at this age a significant number of CD3ε^+ cells were also found in association with follicles. The colocalization of IL-2 expression and CD3ε^+ cells suggests that IL-2 expression is induced when T cells are in contact with hair follicles. In contrast, neither IL-2 mRNA nor IL-2 protein were readily detected once T-cell density in the skin reached steady-state proportions. At this point, T cells were no longer found associated with hair follicles but were evenly distributed throughout the epidermis. In addition, IL-2 expression in the skin was contingent upon the presence of mature T cells therein and induction of IL-2 protein synthesis in the skin did not depend on the expression of a specific TcR on resident T cells. These newly disclosed properties of IL-2 expression in the skin indicate that IL-2 may play an additional role in controlling mature T-cell proliferation by participating in the extrathymic expansion of T cells, particularly those associated with the epidermis.

Finally, regarding IL-2 expression and protein synthesis in the gut, IL-2 producing cells were found associated with the lamina propria of neonatal animals and gut-associated IL-2 production persisted throughout life. In older animals, the frequency of IL-2 producing cells in the small intestine was not identical to that in the large intestine and this difference may reflect regional specialization of the mucosal immune system in response to enteric antigen. Similar to other instances of IL-2 gene expression in vivo, a failure to generate mature T cells also led to an abrogation of IL-2 protein production in the gut. The presence of IL-2 producing cells in the neonatal gut suggested that these cells may be generated during fetal development. Examination of the fetal gut to determine the distribution of IL-2 producing cells therein indicated that there was a tenfold increase in the number of gut-associated IL-2 producers at day 20 of gestation compared to that observed four days earlier and there was little difference between the frequency of IL-2 producing cells in prenatal versus neonatal gut. The origin of these fetally-derived IL-2 producing cells is unclear. Prior to the immigration of IL-2 inducible cells to the fetal gut and/or induction of IL-2 expression therein, IL-2 protein was observed in the fetal liver and fetal omentum, as well as the fetal thymus. Considering that induction of IL-2 protein synthesis may be an indication of future functional capability, detection of IL-2 producing cells in the fetal liver and fetal omentum raises the possibility that IL-2 producing cells in the fetal gut may be extrathymic in origin and IL-2 producing cells in these fetal tissues may not belong solely to the T lineage. Overall, these results provide increased understanding of the nature of IL-2 producing cells in the gut and how the absence of IL-2 production therein and in fetal hematopoietic tissues can result in the acute pathology observed in IL-2 deficient animals.

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Calado, Vanda Luísa de Figueiredo. "Cobertura jornalística de congressos e convenções partidárias na imprensa portuguesa em momentos pré-eleitorais : os finais de mandato de Cavaco Silva e António Guterres." Master's thesis, 2012. http://hdl.handle.net/10071/5183.

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A crescente mediatização das sociedades conduziu à reorganização do espaço da ação política, fazendo com que os acontecimentos políticos funcionem enquanto rituais mediáticos. Nesta reorganização dos espaços simbólicos, os media ganham um poder crescente e, enquanto veículos de transmissão de informação, acarretam consequências ao nível das formas comunicacionais dos campos político e social. Nesse sentido, desempenham uma função de mediação entre os acontecimentos e o produto final que chega ao público, selecionando e reconstruindo a realidade. A mediação é um processo estruturante desta experiência mediática, no qual atuam em conjunto os media e as organizações políticas, num esforço de cooperação tendo em vista a visibilidade dos acontecimentos. O processo de mediação jornalística tem como resultado final o discurso dos media. A construção jornalística conta uma «estória», enquadrando-a através de esquemas de interpretação que caracterizam e balizam o trabalho jornalístico – através de processos de seleção da matéria noticiável, de correspondência a critérios de valor-notícia, de constrangimentos do trabalho jornalístico – fornecendo uma interpretação dos assuntos noticiados, constituindo-se como um instrumento de criação de realidade. Este trabalho pretende caracterizar precisamente o discurso jornalístico na imprensa portuguesa sobre os congressos e convenções partidárias em dois períodos temporais distintos – 1994/1995 e 2000/2001 – que correspondem aos finais de mandato de Cavaco Silva e António Guterres. Para tal, recorreu-se à análise de conteúdo de peças jornalísticas na imprensa portuguesa sobre os eventos partidários que se realizaram nesses momentos, através de uma grelha de análise que pretende agrupar significações ao nível da substância dos textos.
The increasing mediatisation of societies led to the reorganization of the political action arena, thus turning political events into media rituals. This reorganization of symbolic spaces increasingly empowers the media, as they become means for delivering information, and which brings consequences in terms of forms of communication of both political and social fields. They therefore play a role of mediation between the events and the final product that is made available to the public by selecting and reconstructing reality. Mediation is a structuring process of this media experience where both media and political organizations act together in an effort of cooperation with a view to obtaining visibility to the events. The final result of the journalistic mediation process is the media discourse. Journalistic construction tells a story which is framed by interpretation schemes that characterize and limit journalistic activity – by means of selection processes of newsworthy items, matching of news value criteria, constraints on the journalistic field – thus providing an interpretation of the reported items, and becoming an instrument for creating reality. This paperwork intends to portray journalistic discourse related to political party congresses and conventions in the Portuguese press in two distinct periods: 1994/1995 and 2000/2001. These periods correspond to the end of Cavaco Silva and António Guterres terms of office as Prime- Ministers. For this, a content analysis of journalistic items in the press related to political party events that took place at that specific period of time has been made. An analysis grid was used in order to group meanings in terms of substance of the texts.

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Bergeron, Thomas. "Personnalité et politique : comment les traits de personnalité influencent la citoyenneté." Thesis, 2020. http://hdl.handle.net/1866/24422.

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Un intérêt croissant pour les prédispositions individuelles est apparu au cours des deux dernières décennies en psychologie politique. Une grande variété de sujets a été étudiée comme la participation politique et électorale, les connaissances politiques, les attitudes et l'identification partisane. Ces études sont généralement basées sur le modèle du Big Five, avançant que cinq traits résumeraient la personnalité des individus. Ceux-ci sont l'ouverture à l’expérience, l'extraversion, l'agréabilité, la conscienciosité et la stabilité émotionnelle. La plupart des publications évaluant le lien entre la personnalité et la politique se concentrent sur les effets directs. Cependant, le modèle du Big Five suggère clairement que la relation entre les traits et les attitudes, comportements et identités politiques est également indirecte. En utilisant les données de l'American National Election Study de 2012 et 2016, j’analyserai d'abord comment la personnalité affecte la partisanerie, le choix électoral, l'intérêt politique et les attitudes envers le changement climatique. Je confirme que la personnalité a un effet direct sur les points de vue politiques. Deuxièmement, les effets de médiation de trois valeurs seront étudiées: l'idéologie, l'égalitarisme et le traditionalisme moral. L'analyse de médiation permet de décomposer l'effet causal total (ATE) en deux: l'effet moyen de médiation causale (ACME) et l'effet direct moyen (ADE). Je trouve que la plupart des effets sont médiés par l'idéologie, le traditionalisme moral et l'égalitarisme. 80% des associations sont médiées par au moins une valeur. Par conséquent, cette étude fournit des résultats suggérant que la personnalité est un facteur important dans l'explication des attitudes, des comportements et de l'identité partisane, et elle indique que les valeurs sont un mécanisme par lequel la personnalité a un effet.
A growing interest in individuals’ predispositions has emerged over the last two decades in political psychology. A wide variety of topics have been studied, such as turnout, political knowledge, attitudes, participation, and partisan identification. These studies are usually based on the Big Five model, arguing that five traits would summarize the personality of individuals. The five traits are openness to experience, extroversion, agreeableness, conscientiousness, and neuroticism. Most of the literature assessing the link between personality and politics focuses on the direct effects. However, the Big Five model clearly states that the relationship between traits and political attitudes, behaviours, and identities is also indirect. Using the data from the American National Election Study of 2012 and 2016, we firstly analyze how personality affects partisanship, vote choice, political interest, and attitudes toward climate change. We confirm that personality does have a direct effect on political outlooks. Secondly, we focus on the mediation effects of three values: ideology, egalitarianism, and moral traditionalism. The mediation analysis allows us to decompose the total causal (ATE) effect in two: the average causal mediation effect (ACME) and the average direct effect (ADE). We find that most of the effects are mediated by ideology, moral traditionalism, and egalitarianism. 80% of the associations are mediated by at least one mediator. Hence, this study offers evidence that personality is an important factor in the explanation of attitudes, behaviours, and partisan identity, and it indicates that values are an important mechanism through which personality has an effect.

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Fuchsová, Michaela. "Právní rámec řešení sporů z mezinárodního obchodního styku v České republice a ve Francii." Doctoral thesis, 2016. http://www.nusl.cz/ntk/nusl-353615.

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LEGAL FRAMEWORK OF INTERNATIONAL TRADE DISPUTES RESOLUTION IN THE CZECH REPUBLIC AND IN FRANCE Comparative study of legal regulation in the Czech Republic and in France with emphasis on point of view of extent and limits of parties' autonomous will within dispute resolution ABSTRACT In relation to an important and continuously increasing growth of international trade and economic cooperation, a logic and proportionally increasing fact occurs, namely the existence and necessity of resolution of disputes arising out of such cooperation and business relationships. This dissertation focuses on specific area of such relations - on solution of property disputes in international trade and business relations arising out on private law basis between entrepreneurs and which affect in any manner the territories, more precisely the jurisdictions and the legal orders of two particular states, and that of France and the Czech Republic. The aim of the dissertation is to examine the extent of autonomous will, which the parties may assert within various methods of disputes resolution and to notify of its limits set by the respective legal regulation. Considering namely the main criteria of examination - i.e. the extent and limits of autonomous will of the parties within the dispute resolution - the author concentrates more...

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Esequiel, Bruna Marques. "Relatório de estágio realizado no Julgado de Paz do Seixal." Master's thesis, 2017. http://hdl.handle.net/10362/21693.

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The purpose of this report is to report the experience of the internship on Justice of the Peace Court in Seixal during the four-month period from September to December 2016, within the scope of the third semester of the Master's Degree in Forensic Law and Arbitration. As a main element it focuses on the Justices of the Peace Court as a whole and mainly, as a means of the fair composition of litigation and of civic participation of the parties, a singular aspect with great importance, which gave rise to the theme. The report begins with the description of the stage - reasons for its accomplishment, the way it has developed and the reason for choosing the theme. In development, it is divided into two major parts, the first dedicated to the Justices of the Peace Court, as an elementary part of the framework of the theme, which focuses on the main lines, their organization, procedure and controversial issues; The second part explores, the actions of the parties and those involved in the civil proceeding, as opposed to justice in this court and in the Judicial Court, in a shared justice perspective; later conclusion of the study with the position around the theme.
O presente relatório tem como objectivo relatar os conhecimentos teórico-práticos adquiridos durante o Estágio no Julgado de Paz do Seixal, no período de quatro meses – de Setembro a Dezembro de 2016 - no âmbito do terceiro semestre do Mestrado em Direito Forense e Arbitragem. Como elemento principal foca o Julgado de Paz como um todo e, principalmente, como meio da justa composição de litígios e de participação cívica das partes, aspecto singular e de grande importância, o qual deu origem ao tema. O relatório inicia com a descrição do estágio - razões da sua realização, em que moldes se desenvolveu e motivo da escolha do tema. No desenvolvimento, divide-se em duas grandes partes, a primeira dedicada aos Julgados de Paz, como parte elementar ao enquadramento do tema, onde são focadas as linhas mestras, respectiva organização, tramitação e questões polémicas; a segunda parte explora a actuação das partes e dos envolvidos no processo civil, por contraposição da justiça neste tribunal e no Tribunal Judicial, numa perspectiva de Justiça Partilhada; por último cabe a conclusão do estudo com a tomada de posição a cerca do tema.

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Dissertations / Theses on the topic 'Partial mediation'

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