Academic literature on the topic 'Papillomaviruses Diagnosis'

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Journal articles on the topic "Papillomaviruses Diagnosis"

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Korsak, K. S., and E. V. Voropaev. "Phylogenetic features of papillomaviruses and their significance in the diagnosis of papillomavirus infection." Health and Ecology Issues, no. 4 (December 28, 2020): 23–28. http://dx.doi.org/10.51523/2708-6011.2020-17-4-3.

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Viruses belonging to the Papillomaviridae family have been isolated from mammals, birds and reptiles. The analysis of the genome structure of more than 240 different types of papillomaviruses has made it possible to better understand their evolutionary path. The existing data indicate that many diverse evolutionary mechanisms have influenced their phylogenetic tree. For more than 400 million years, papillomaviruses have occupied various ecological niches. Niche sorting was followed by extensive periods of host-parasite co-evolution. Adaptation to different host tissues, as well as to changing environmental conditions can explain some features of the members of the Papillomaviridae family, one of which is human papillomavirus (HPV), having an important clinical significance. The study of the driving mechanisms of the evolution will help to change the notions about HPV virulence, character of its spread, epidemiology, as well as the pathogenesis and the course of oncologic diseases caused by it. This review highlights some moments of the evolutionary history of papillomaviruses which created a background for the development of oncogenic features of certain HPV types.
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Unger, Elizabeth R. "In Situ Diagnosis of Human Papillomaviruses." Clinics in Laboratory Medicine 20, no. 2 (June 2000): 289–301. http://dx.doi.org/10.1016/s0272-2712(18)30063-5.

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Sanz, Alexandra, Erica Miller, Nikki Harley, and Laura Coffee. "Papillomatosis in a raccoon (<em>Procyon lotor</em>)." Wildlife Rehabilitation Bulletin 40, no. 1 (October 7, 2022): 22–26. http://dx.doi.org/10.53607/wrb.v40.255.

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Papillomaviruses are species-specific double-stranded DNA viruses with at least 50 species of mammals. Although well-studied in humans, papillomaviruses in the raccoon (Procyon lotor) are not well characterized, and few cases have been published. Therefore, when the disease is encountered in a rehabilitation center, definitive diagnosis and treatment in the raccoon can be unclear. This case study outlines the characteristic gross and histologic lesions of an affected individual to facilitate identification and treatment of this disease in the future. In the case of this juvenile raccoon, ulcerated exophytic lesions on the bridge of its nose and right forelimb digit were seen grossly, with the presence of koilocytes and hyperkeratosis observed histologically. These findings are consistent with other documented cases of papillomavirus in raccoons and canines. Affected raccoons do not require extensive treatment, as raccoon papillomatosis is considered self-limiting.
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Greenblatt, Rebecca J. "Human papillomaviruses: Diseases, diagnosis, and a possible vaccine." Clinical Microbiology Newsletter 27, no. 18 (September 2005): 139–45. http://dx.doi.org/10.1016/j.clinmicnews.2005.09.001.

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Frías, Isaac A. M., Karen Y. P. S. Avelino, Rafael R. Silva, César A. S. Andrade, and Maria D. L. Oliveira. "Trends in Biosensors for HPV: Identification and Diagnosis." Journal of Sensors 2015 (2015): 1–16. http://dx.doi.org/10.1155/2015/913640.

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The conventional methodologies used for the detection of human papillomavirus (HPV) present actually robust and reproducible advantages. However, at the same time, they involve complex protocols that sometimes are difficult to popularize. Over the first half of XX century, the adequate treatment of complex and delicate processes from a simple instrumental base seemed a fundamental and intrinsic contradiction. However, interdisciplinary trends have allowed the manipulation of tissues, proteins, and nucleic acids through innovative increasingly smaller devices. The proper diagnosis of HPV has seen great advances since biosensor researchers are employing its virus strains as models to study the interactions between the biorecognition element and the transducer. Additionally, all recent improvements and trends that material sciences, biotechnology, and data processing scientists excel for biosensors can be applied for the HPV detection platforms. In this review, we highlight the recent trends on materials, nanomaterials, and transducers for the specific detection and differentiation of HPV strains. The most influential methods for the detection and identification of these papillomaviruses include optical, electrochemical, and piezoelectric transducers; we will visit their sensibility and advantages. Additionally, we highlight the factors that contributed to the increasing importance of these biodevices as potential substitutes to conventional diagnostic methods.
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Alexander, Kenneth A., and William C. Phelps. "Recent advances in diagnosis and therapy of human papillomaviruses." Expert Opinion on Investigational Drugs 9, no. 8 (August 2000): 1753–65. http://dx.doi.org/10.1517/13543784.9.8.1753.

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Silverberg, Steven G. "Molecular Diagnosis and Prognosis in Gynecologic Oncology." Archives of Pathology & Laboratory Medicine 123, no. 11 (November 1, 1999): 1035–40. http://dx.doi.org/10.5858/1999-123-1035-mdapig.

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Abstract Currently, molecular pathology plays a limited role in improving patient outcome in gynecologic oncology. However, molecular investigation is providing important insights into the epidemiology, pathogenesis, and progression of female genital cancers. Future roles should include prediction of poor outcome in low-risk cases, more accurate staging of multifocal tumors, identification of new precursor lesions, and prediction of response to specific therapeutic regimens. Gene therapy of some malignant tumors may become important in the near future. In the immediate future, however, the most significant role of molecular pathology may be in the screening and triage of putative cervical cancer precursors and in the possible prophylaxis of these lesions by means of a vaccine or vaccines against human papillomaviruses.
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Dunjic, Momir, Slavisa Stanisic, Dejan Krstic, Miodrag Stanisic, Z. Jovanovic Ignjatic, and Marija Dunjic. "Integrative Approach to Diagnosis of Genital Human Papillomaviruses (HPV) Infection of Female." Acupuncture & Electro-Therapeutics Research 39, no. 3 (October 10, 2014): 229–39. http://dx.doi.org/10.3727/036012914x14109544776051.

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Coutlee, François, Danielle Rouleau, Alex Ferenczy, and Eduardo Franco. "The Laboratory Diagnosis of Genital Human Papillomavirus Infections." Canadian Journal of Infectious Diseases and Medical Microbiology 16, no. 2 (2005): 83–91. http://dx.doi.org/10.1155/2005/798710.

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Human papillomaviruses (HPVs) are the etiological agents of several genital cancers, including cancer of the uterine cervix. The detection of HPV infection in genital samples may increase the sensitivity of primary and secondary screenings of cervical cancer. HPV testing may also improve the specificity of screening programs, resulting in the avoidance of overtreatment and cost savings for confirmatory procedures. The major determinants of clinical progression of HPV infection include persistence of HPV infection, involvement of high-risk HPV types, high HPV viral load, integration of viral DNA and presence of several potential cofactors. Signal amplification HPV-DNA detection techniques (Hybrid Capture II, Digene Corporation, USA) are standardized, commercially available, and capable of detecting several high-risk HPV types. They also increase the sensitivity of screening for high-grade lesions in combination with cytology. The sensitivity of these techniques to detect high-grade lesions is higher than that of cytology, but the referral rate for colposcopy is greater. These techniques are approved for the triage to colposcopy of women with cervical smears interpreted as atypical squamous cells of undetermined significance. Triage and screening for cervical cancer using HPV will probably be restricted to women aged 30 years or older because of the high prevalence of infection in younger women. Amplification techniques are ideal for epidemiological studies because they minimize the misclassification of HPV infection status. These techniques can detect low HPV burden infections. Consensus primers amplify most genital types in one reaction, and the reverse hybridization of amplicons with type-specific probes allows for the typing of HPV-positive samples. Consensus PCR assays are currently under evaluation for diagnostic purposes. HPV testing is currently implemented for the clinical management of women.
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Spinillo, Arsenio A., Mattia M. Dominoni, Anna A. C. Boschi, Cecilia C. Sosso, Giacomo G. Fiandrino, Stefania S. Cesari, and Barbara B. Gardella. "Clinical Significance of the Interaction between Human Papillomavirus (HPV) Type 16 and Other High-Risk Human Papillomaviruses in Women with Cervical Intraepithelial Neoplasia (CIN) and Invasive Cervical Cancer." Journal of Oncology 2020 (October 26, 2020): 1–9. http://dx.doi.org/10.1155/2020/6508180.

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The aim is to evaluate the clinical consequences of coinfection between HPV 16 and other high-risk HPVs among women with a histological diagnosis of CIN or invasive cervical cancer. A total of 2985 women, with a diagnosis of either CIN or cancer (<IB) on cervical or cone biopsy, were included. HPV genotypes were identified using the INNO-LiPA HPV genotyping assay, version EXTRA, on cervical scraping, before the colposcopic evaluation and the colposcopic biopsies or conization. In the overall population, HPV16 interacted positively with HPV18 (RR = 2, 95% CI 1.5–2.6) and negatively with HPV33, 51, 52, and 66, in log-linear analysis. There was an excess of CIN3 diagnoses among subjects coinfected with HPV16 and HPV18 or HPV52, although the absolute number of cases was relatively small. In a logistic model, the odds ratio of CIN3+ associated with coinfection of HPV16 and HPV18 (OR = 3.8, 95% CI 2.5–5.7, p = 0.004 compared to single HPV16) or HPV52 (OR = 3.6, 95% CI 2.6–5.1, p = 0.009 compared to single HPV) was higher than that associated with single HPV 16 infections. Finally, multiple infections had no effect on residual disease and did not influence the recurrence of high-grade CIN during a median follow-up of 25 months (IR 17–41). HPV16 interacted positively with HPV18 and negatively with HPV33, 51, 52, and 66 supporting the notion that HPV16 interacts mostly negatively with other HR-HPVs in CIN lesions. Among specimens coinfected with HPV16 and 18 or 52, there was an excess of CIN3+ although the impact on the prevalence of severe cervical lesions was limited.
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Dissertations / Theses on the topic "Papillomaviruses Diagnosis"

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Kwan, Tak-ching Tracy, and 關德貞. "Human papillomavirus testing in cervical cancer screening: potential harms and implications for intervention." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2011. http://hub.hku.hk/bib/B4658836X.

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Sze, S. M. Candy, and 施少妹. "Evaluation and comparison of molecular diagnostic methods for detection of human papillomavirus (HPV) in relation to cervicalneoplasia." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2006. http://hub.hku.hk/bib/B4501145X.

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Sze, S. M. Candy. "Evaluation and comparison of molecular diagnostic methods for detection of human papillomavirus (HPV) in relation to cervical neoplasia /." View the Table of Contents & Abstract, 2006. http://sunzi.lib.hku.hk/hkuto/record/B37552752.

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Carcopino, Xavier. "Signification de la charge virale des papillomavirus humains oncogènes de type 16 et 18." Thesis, Aix-Marseille 2, 2011. http://www.theses.fr/2011AIX20704/document.

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En utilisant une technique originale de détection et de quantification des HPV16 et 18 par PCR duplex, ce travail de thèse illustre la signification, l’intérêt et les limites de l’utilisation clinique de la mesure de la charge virale pour ces deux types d’hrHPV. Si nous n’avons pas démontré de réelle signification de la charge virale en HPV18, il n’en est pas de même pour l’HPV16 dont la charge virale augmente avec la sévérité des lésions constatées. Néanmoins, l’extrême variabilité des charges virales mesurées limite son utilisation en pratique clinique. Après un frottis cervico-utérin (FCU) anormal, une charge virale seuil en HPV16 à 3,0x106 copies par millions de cellules permet la prédiction optimale de la présence d’une CIN2+ (spécificité : 91 % et sensibilité : 58,2 %). Cette valeur seuil est particulièrement performante pour les patientes ayant un FCU de bas grade (spécificité : 96,4 % et sensibilité : 88 %). Si la charge virale en HPV16 et 18 ne semble pas être prédictive de la clairance virale chez les jeunes femmes de moins de 30 ans ayant un FCU normal, elle l’est chez les patientes HPV16 positives ayant une colposcopie normale malgré un FCU équivoque ou de bas grade (spécificité : 86,7 % et sensibilité : 85,7 %)
Using duplex PCR technique for the detection and quantification of HPV16 and 18, this work investigates the significance, value and limitations of the use of HPV16 and 18 viral load quantitation in routine clinical practice. Although HPV18 viral load was not found to be of any clinical relevance, HPV16 viral load was found to significantly increase with the severity of cervical lesions. However, the wide range of viral load observed strongly limitates its use in routine clinical practice. After an abnormal cervical cytology, a HPV16 viral load cut-off of 3.0x106 copies per million cells allows for the best prediction of CIN2+ (91% specificity and 58.2% sensitivity). Such cut-off is particularly efficient in case of low grade abnormal cytology (96.4% specificity and 88% sensitivity). Although HPV16 viral load does not appear to predict for HPV16 clearance in women under 30 with normal cytology, such prediction was observed among women with normal colposcopy following equivocal or low grade cytology (86.7% specificity and 85.7% sensitivity)
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Correr, Wagner Rafael. "Development of impedimetric DNA sensor for diagnosis of Human Papillomavirus type 18 infection." Universidade de São Paulo, 2014. http://www.teses.usp.br/teses/disponiveis/76/76132/tde-05032015-144417/.

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Currently, the most common strategy employed to detect DNA sequences is PCR (Polymerase Chain Reaction). Nevertheless, in the last few years research on DNA biosensors has increased significantly. Such sensors represent an alternative to PCR in the detection of specific DNA sequences, once they exhibit fast response, low limits of detection, and require simpler sample preparation. The development of a biosensor for detection of DNA from Human Papillomavirus type 18 is reported. To immobilise DNA probe onto indium-tin oxide (ITO) electrodes, a silanisation was carried out using 3-Aminopropyltryethoxysilane (APTES). Silanisation was studied and optimised using ultra-violet absorption spectroscopy, atomic force microscopy, fluorescence microscopy, and cyclic voltammetry. After immobilisation, the hybridisation with target sequence is detected by changes in surface properties of ITO electrode by Cyclic Voltammetry and Electrochemical Impedance Spectroscopy, using the Ferri-Ferrocyante redox couple. The detection of synthetic target sequence was performed in the range of 12.5 to 100 nM, and 300nM for PCR products. The sensor did not show significative response for non-complementary sequence at 50 nM. This sensor can be applied for fast and low cost detection of HPV genetic material at nanomolar levels.
A estratégia mais empregada atualmente na detecção de sequência de DNA é a PCR (Reação em Cadeira da Polimerase). Contudo, nos últimos anos, a pesquisa em biossensores de DNA tem aumentado significativamente. Estes sensores representam uma alternativa a PCR na detecção de sequências específicas de DNA, uma vez que exibem resposta rápida, baixos limites de detecção e requerem preparação simples da amostra. Nesta dissertação descrito o desenvolvimento de um biossensor para a detecção do DNA do Papilomavirus Humano tipo 18. A fim de imobilizar a sequência de captura de DNA em eletrodos de óxido de estanho e índio (ITO), realizou-se uma silanização usando 3-Aminopropiltrietoxisilano (APTES). A reação de silanização foi estudada e otimizada através das técnicas de Espectroscopia de Absorção Ultravioleta, Microscopia de Força Atômica, Microscopia de Fluorescência e Voltametria Cíclica. Após a imobilização, a hibridização com a sequência alvo é detectada através de alterações nas propriedades de superfície do eletrodo através de Voltametria Cíclica e Espectroscopia de Impedância Eletroquímica, usando o par redox Ferri-ferrocianeto. A detecção da sequência alvo sintética foi realizada no intervalo de 12.5 a 100 nM, e para o produto de PCR, 300 nM. O sensor não demonstrou resposta significativa para sequência não complementar a 50 nM. Este sensor pode ser aplicado na detecção rápida e de baixo custo de material genético do HPV a níveis nanomolares.
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Trollé, Sylvine. "Infections à papillomavirus humains : application d'une méthode de détection génomique par la réaction de polymérisation en chaîne." Paris 5, 1995. http://www.theses.fr/1995PA05P115.

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Bouchot, Olivier. "Cancer du pénis : diagnostic et indications thérapeutiques à partir d'une série de 49 cas." Nantes, 1985. http://www.theses.fr/1985NANT3462.

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Barbieri, Daniela <1985&gt. "Human papillomavirus (HPV) and associated diseases: between applied diagnostic and basic research." Doctoral thesis, Alma Mater Studiorum - Università di Bologna, 2013. http://amsdottorato.unibo.it/5314/.

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Human Papillomavirus (HPV) is the cause of cervical cancers (among these, adenocarcinoma, AdCa) and is associated to a subgroup of oropharyngeal carcinomas (OPSCCs). Even if the risk for cancer development is linked to the infection by some viral genotypes, mainly HPV16 and 18, viral DNA alone seems not to be sufficient for diagnosis. Moreover, the role of the virus in OPSCCs has not been totally clarified yet. In the first part of the thesis, the performances concerning viral genotyping in clinical cervical samples of a new pyrosequencing-based test and a well-known hybridization-based assay have been compared. Similar results between the methods have been obtained. However, the former showed advantages in detecting intratype variants, higher specificity and a broader spectrum of detectable HPV types. The second part deals with the evaluation of virological markers (genotyping, viral oncoproteins expression, viral load, physical state and CpG methylation of HPV16 genome) in the diagnosis/prognosis of cervical AdCa and HPV-associated OPSCCs. HPV16 has been confirmed the most prevalent genotype in both the populations. Interestingly, the mean methylation frequency of viral DNA at the early promoter showed the tendency to be associated to invasion for cervical AdCa and to a worse prognosis for OPSCCs, suggesting a promising role as diagnostic/prognostic biomarker. The experiments of the third part were performed at the DKFZ in Heidelberg (Germany) and dealt with the analysis of the response to IFN-k transfection in HPV16-positive cervical cancer and head&neck carcinoma cell lines to evaluate its potential role as new treatment. After 24h, we observed increased IFN-b expression which lead to the up-regulation of genes involved in the antigens presentation pathway (MHC class I and immunoproteasome) and antiviral response as well, in particular in cervical cancer cell lines. This fact suggested also the presence of different HPV-mediated carcinogenic pathways between the two anatomical districts.
Il Papillomavirus umano (HPV) è causa dei carcinomi della cervice uterina (tra cui adenocarcinomi, AdCa) ed è associato ad un sottogruppo di tumori dell’orofaringe (OPSCCs). Nonostante il rischio di sviluppo di tumore sia associato all’infezione da parte di alcuni genotipi virali, principalmente HPV16 e 18, il DNA virale da solo sembra non essere sufficiente in campo diagnosico. Inoltre, per tumori orofaringei il ruolo del virus non è ancora del tutto chiaro. Nella prima parte della tesi, sono state confrontate le performance riguardo la genotipizzazione di HPV su campioni clinici cervicali di una tecnica innovativa, basata su amplificazione e pirosequenziamento, e una di routine, basata su amplificazione e ibridazione inversa. Lo studio ha evidenziato performance simili tra le due metodiche, sottolineando per il sequenziamento una maggiore specificità e capacità di rilevare varianti intratipo. Nella seconda parte sono stati analizzati marker virologici (genotipizzazione, espressione delle oncoproteine virali, carica virale, stato fisico e metilazione del genoma di HPV16) in funzione dei dati clinici disponibili, per un possibile impiego nella diagnosi/prognosi di AdCa cervicali e OPSCCs HPV-associati. HPV16 si è confermato il genotipo prevalente in entrambe le popolazioni. La frequenza di metilazione nel promotore precoce virale ha mostrato una tendenza ad essere associata ad invasione negli AdCa, e ad una prognosi peggiore negli OPSCCs, emergendo come il più promettente marker diagnostico/prognostico. La terza parte, svolta presso il DKFZ di Heidelberg (Germania), ha visto l’analisi della risposta alla transfezione di IFN-k in linee cellulari tumorali HPV16-positive della cervice uterina e della regione testa-collo, per valutarne l’impiego terapeutico. Dopo 24h, è stato osservato un incremento dell’espressione di IFN-b e, di conseguenza, una up-regolazione dei geni coinvolti nella presentazione antigenica (MHC classe I ed immunoproteasoma) e nella risposta antivirale, specialmente nelle cellule cervicali, suggerendo la presenza di diversi meccanismi patogenetici tra tumori HPV-positivi dei due distretti anatomici.
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RIHET, STEPHANE. "Diagnostic et pronostic des lesions de bas grade du col uterin liees aux papillomavirus humains." Amiens, 1997. http://www.theses.fr/1997AMIE0102.

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Le cancer du col uterin est un probleme majeur de sante publique, du fait de sa frequence et de son taux de mortalite. Des anomalies precancereuses peuvent etre detectees et traitees grace au depistage de masse, realisable par un frottis cervico-vaginal. Nous nous sommes interesses au diagnostic et au pronostic des lesions de bas grade du col uterin par la recherche conjointe de papillomavirus humain (hpv) et par l'etude de la quantification de l'adn par analyse d'image (ploidie cellulaire). Nous avons demontre clairement l'interet de ces deux etudes complementaires des diagnostics cytologiques et histologiques, dans les lesions de bas grade du col uterin. La detection d'hpv oncogenes et l'appreciation de leur integration potentielle sont des donnees permettant d'apprecier la persistance voire l'evolutivite des lesions. La quantification d'adn par analyse d'images nous a permis d'isoler trois profils principaux de ploidie : le profil diploide, le profil aneuploide compose lui meme de deux profils : aneuploide un pic et multiploide. La presence d'un hpv oncogene seul tout comme celle d'un profil aneuploide seul, ne permet pas toujours de predire l'evolution d'une lesion. En revanche, une lesion de bas grade presentant des hpv oncogenes, de surcroit integres, avec un profil aneuploide mais surtout multiploide, correspond a une lesion potentiellement maligne ; une lesion de haut grade pouvant d'autre part etre situee a proximite. En definitif, l'etude conjointe de la quantification d'adn par analyse d'image et de la detection d'hpv oncogenes, assure une nouvelle et meilleure approche du pronostic de l'evolution des lesions de bas grade mais aussi de haut grade du col uterin.
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Monlun, Eric. "Diagnostic virologique des infections a papillomavirus de type 16 et 18 : mise au point d'une technique d'amplification genomique (pcr : [polymerase chain reaction])." Université Louis Pasteur (Strasbourg) (1971-2008), 1990. http://www.theses.fr/1990STR1M093.

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Books on the topic "Papillomaviruses Diagnosis"

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United States. Congress. House. A bill to amend title XVIII of the Social Security Act to provide for Medicare coverage of screening tests for human papillomavirus (HPV). Washington, D.C: U.S. G.P.O., 2007.

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1913-, Ferenczy Alex, and Richart Ralph M. 1933-, eds. Electrosurgery for HPV-related diseases of the lower genital tract: A practical handbook for diagnosis and treatment by loop electrosurgical excision and fulguration procedures. New City, New York, USA: Arthur Vision ; Anjou, Quebec, Canada : BioVision, 1992.

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Kühn, Wolfgang. Kolposkopie in Klinik und Praxis. Berlin: De Gruyter, 2011.

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Kühn, Wolfgang. Kolposkopie in Klinik und Praxis. 2nd ed. Berlin: De Gruyter, 2013.

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Benign to malignant progression in cervical squamous epithelium. New York: Igaku-Shoin, 1994.

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Rosenblatt, Alberto. Human Papillomavirus: A Practical Guide for Urologists. Berlin, Heidelberg: Springer-Verlag Berlin Heidelberg, 2009.

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Handbook of colposcopy: Diagnosis and treatment of lower genital tract neoplasia and HPV infections. Boston: Little, Brown, 1989.

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Schillinger, Julia Ann. Detection of human papillomavirus by nucleic acid hybridization as an adjunct to the papanicolaou smear. [New Haven: s.n.], 1990.

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International, Tutorial on Colposcopy and Colposcope-directed Treatment Procedures (1st 1985 Hamburg Germany). Colposcopy in diagnosis and treatment of preneoplastic lesions. Berlin: Springer-Verlag, 1988.

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PCR in situ hybridization: Protocols and applications. 2nd ed. New York: Raven Press, 1994.

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Book chapters on the topic "Papillomaviruses Diagnosis"

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Pfister, Herbert. "Papovaviridae: The Papillomaviruses." In Laboratory Diagnosis of Infectious Diseases Principles and Practice, 301–16. New York, NY: Springer New York, 1988. http://dx.doi.org/10.1007/978-1-4612-3900-0_16.

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Jochmus, Ingrid, and Lutz Gissmann. "Immunological Aspects of the E6 and E7 Oncogenes: Tools for Diagnosis and Therapeutic Intervention." In Papillomaviruses in Human Cancer, 137–65. Boston, MA: Springer US, 1997. http://dx.doi.org/10.1007/978-1-4757-6127-6_5.

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Ikenberg, Hans. "Laboratory Diagnosis of Human Papillomavirus Infection." In Human Papillomavirus, 166–74. Basel: S. KARGER AG, 2014. http://dx.doi.org/10.1159/000356515.

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Voytek, Theresa M., and Gregory J. Tsongalis. "Human Papillomavirus." In Molecular Diagnostics, 447–51. Totowa, NJ: Humana Press, 2006. http://dx.doi.org/10.1385/1-59259-928-1:447.

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Tschandl, Philipp, Cliff Rosendahl, and Harald Kittler. "Cutaneous Human Papillomavirus Infection: Manifestations and Diagnosis." In Human Papillomavirus, 92–97. Basel: S. KARGER AG, 2014. http://dx.doi.org/10.1159/000355966.

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Wagner, D. "Cervical HPV Diagnosis: Colposcopy, Cytology, Histology." In Genital Papillomavirus Infections, 127–32. Berlin, Heidelberg: Springer Berlin Heidelberg, 1990. http://dx.doi.org/10.1007/978-3-642-75723-5_9.

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Arbefeville, Sophie S., and Aaron D. Bossler. "Human Papillomavirus." In Diagnostic Molecular Pathology in Practice, 269–75. Berlin, Heidelberg: Springer Berlin Heidelberg, 2011. http://dx.doi.org/10.1007/978-3-642-19677-5_33.

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Burd, Eileen M., and Christina L. Dean. "Human Papillomavirus." In Diagnostic Microbiology of the Immunocompromised Host, 177–95. Washington, DC: ASM Press, 2016. http://dx.doi.org/10.1128/9781555819040.ch8.

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McDougall, James K., Anna M. Beckmann, and Nancy B. Kiviat. "Methods for Diagnosing Papillomavirus Infection." In Ciba Foundation Symposium 120 - Papillomaviruses, 86–103. Chichester, UK: John Wiley & Sons, Ltd., 2007. http://dx.doi.org/10.1002/9780470513309.ch7.

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Stegner, H. E. "HPV Infection and Precancer in Gynaecology — Diagnosis and Therapeutic Aspects." In Genital Papillomavirus Infections, 115–26. Berlin, Heidelberg: Springer Berlin Heidelberg, 1990. http://dx.doi.org/10.1007/978-3-642-75723-5_8.

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Conference papers on the topic "Papillomaviruses Diagnosis"

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Kumar, Anoop, Inderjit Singh Yadav, Rupinder Sekhon, Dwaipayan Bharadwaj, and Mausumi Bharadwaj. "Identification of T- and B-cell epitopes in HPV-16 E7 gene isolated from cervical cancer patients." In 16th Annual International Conference RGCON. Thieme Medical and Scientific Publishers Private Ltd., 2016. http://dx.doi.org/10.1055/s-0039-1685256.

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Introduction: In India, cervical cancer is the most common cancer among females. Persistence infection with high risk human papillomaviruses (HR-HPV) is an etiological agent for cervical cancer development, especially HPV-16 is found to be exclusively high in cervical cancer cases in Indian population. The continuous expression and transforming ability of HPV E7 helps in progression of cervical cancer and other HPV related disease, which make E7 as a suitable targets for the development of therapeutic vaccines. Objectives: Identification of T-& B-cell epitopes HPV-16 E7 gene isolated from in cervical cancer patients. Materials and Methods: A total of 80 cervical cancer tissue biopsies were collected and processed for DNA extraction, HPV diagnosis and genotyping. E7 gene of HPV-16 positive samples were amplified and sequenced. Epitopes in E7 gene sequence were predicted by online freely available tools. Results: In the present study we got 72 samples (90%) were positive for HPV and out of which 68 samples (94.4%) were positive for the HPV-16. HPV-16 positive samples were sequenced and translated. IEDB server was used for epitope analysis; 12 potent epitopes for the MHC-I alleles were identified in isolated E7 gene of HPV-16. The most potent epitopes were MHGDTPTLHEYM for HLA-C*07:01; LLMGTLGIVCPI for HLA-A*02:01 and MHGDTPTLHEYML for HLA-C*07:01; having percentile rank 0.2 for all three and antigencity score of 0.20011, 0.15358 and 0.10735, respectively. Conclusion: This is an effective strategy to design immuno-therapeutics and therapeutic vaccine against HPV using E7 as target. These findings will be helpful in the development of effective vaccine for particular geographical region.
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Faizuloev, E. B., A. N. Kaira, T. R. Uzbekov, A. A. Poromov, E. A. Volynskaya, O. A. Svitich, and V. V. Zverev. "GENETIC STRUCTURE OF HIGH AND LOW RISK HUMAN PAPILLOMAVIRUSES CIRCULATING IN THE RUSSIAN FEDERATION." In Molecular Diagnostics and Biosafety. Federal Budget Institute of Science 'Central Research Institute for Epidemiology', 2020. http://dx.doi.org/10.36233/978-5-9900432-9-9-123.

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Flores, Ryan, Sahra Afshari, and Jennifer Blain Christen. "Colorimetric Point-of-Care Human Papillomavirus Diagnostic Reader." In 2019 IEEE Healthcare Innovations and Point of Care Technologies (HI-POCT). IEEE, 2019. http://dx.doi.org/10.1109/hi-poct45284.2019.8962666.

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Herman, B. "APPLICATIONS OF LASER OPTICAL MICROSCOPIC TECHNIQUES IN DECIPHERING DISEASE SPECIFIC MECHANISMS AND DIAGNOSIS." In Biomedical Optical Spectroscopy and Diagnostics. Washington, D.C.: Optica Publishing Group, 2006. http://dx.doi.org/10.1364/bosd.1996.ft5.

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Accumulating evidence strongly associates human papillomavirus infection with the development of cervical cancers. However, it has also become increasingly clear that HPV infections of the cervix span a wide clinical spectrum from benign lesions to precancerous lesions, with only a minority of infections resulting in invasive cancers, although the reasons for this are not clear. Longitudinal epidemiologic studies using cytologic methods to detect HPV infection have shown that the majority of women infected with HPV will regress spontaneously. In addition, age-stratified data for rates of HPV positivity from cross-sectional studies also suggest that many women clear the infection spontaneously. These results support the concept that many women may be only transiently infected with HPV during their life span and only in women with persistent HPV infection does cervical cancer progress. In addition to persistence of HPV infection, recent epidemiological studies indicate that the amount of high-risk HPV (viral load or HPV gene copy number) in cervicovaginal epithelial cells may be a risk factor for cervical cancer. Thus, a technique which could detect, genotype and quantitate HPV in smears of cervicovaginal epithelial cells would be of major import in assessment of patient clinical status as well as in epidemiological studies relating HPV infection to cervical cancer.
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Peresunko, Olexander P., Ion Gruia, Sergey B. Yermolenko, Nina Horodynska, and Dmitry M. Burkovets. "Diagnosis of cervical cytological smears for availability of papillomavirus by spectropolarimetry." In Advanced Topics in Optoelectronics, Microelectronics and Nanotechnologies 2020, edited by Marian Vladescu, Ionica Cristea, and Razvan D. Tamas. SPIE, 2020. http://dx.doi.org/10.1117/12.2571211.

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Peresunko, Olexander P., Sergey B. Yermolenko, and Nina Horodynska. "Spectropolarimetry diagnostics of cervical cytological smears for availability of papillomavirus." In Applications of Digital Image Processing XLIII, edited by Andrew G. Tescher and Touradj Ebrahimi. SPIE, 2020. http://dx.doi.org/10.1117/12.2568384.

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Kalodimou, Vasiliki E., Marina Kontogiorgi, Apostolos Papalois, and Stefanos Chandakas. "A flow cytometry detection at a protein level of human papillomavirus." In AACR International Conference: Molecular Diagnostics in Cancer Therapeutic Development– Sep 27-30, 2010; Denver, CO. American Association for Cancer Research, 2010. http://dx.doi.org/10.1158/diag-10-b4.

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Wichmann, G., G. Loermann, M. Kolb, S. Fest, A. Dietz, and S. Wiegand. "High-risk Human Papillomavirus (HR-HPV) DNA Detection in Mouth Rinses for Diagnosis of HPV-driven oropharynx cancer." In Abstract- und Posterband – 91. Jahresversammlung der Deutschen Gesellschaft für HNO-Heilkunde, Kopf- und Hals-Chirurgie e.V., Bonn – Welche Qualität macht den Unterschied. © Georg Thieme Verlag KG, 2020. http://dx.doi.org/10.1055/s-0040-1711012.

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Rocha, Willker Menezes da, Camila Freze Baez, Larissa Alves Afonso, Fernanda Nahoum Carestiato, Marianna Tavares Venceslau Gonçalves, Rafael Brandão Varella, and Silvia Maria Baeta Cavalcanti. "The use of DNA microarray assay as a diagnostic tool to study penile cancer associated with human papillomavirus." In XIII Congresso da Sociedade Brasileira de DST - IX Congresso Brasileiro de AIDS - IV Congresso Latino Americano de IST/HIV/AIDS. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/dst-2177-8264-202133p159.

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Introduction: The genital infection by the human papillomavirus (HPV) can result in a sexually transmitted disease associated with precursor lesions for carcinogenesis in the genital tract. In recent years, evidence was accumulated defining HPV as the etiologic agent of cervical cancer; however, the etiology of penile cancer is still open and lacks studies. This study aims to contribute to the epidemiologic knowledge regarding the prevalence of this virus in malignant lesions of the male genital tract, using the DNA microarray assay, a technique that allows the simultaneous detection of up to 32 different HPV genotypes. Objective: The aim of this study was to investigate the presence of HPV in penile malignant lesions, to genotype HPV, when present, to correlate the HPV infection and its genotypes with the histopathological data. Methods: A total of 112 penile cancer samples was collected in a cross-sectional study. The detection methodology consisted of (1) detecting the presence of HPV DNA by the polymerase chain reaction (PCR) technique with generic primers, (2) genotyping the HPV using the DNA microarray assay, and (3) correlation of the histopathology, tumor invasiveness, and the dispersion of malignant cells by the lymph nodes with the presence of HPV. Results: The HPV prevalence was 57.1% (64). The most prevalent genotype was the HPV16 (32.8%), followed by HPV6 (23.4%); HPV18, HPV35, and HPV45 (12.5%); HPV31 (10.9%); and HPV70 (7.8%). Of the HPV-positive samples, 25% were mixed infections. Conclusion: The role of the HPV infection was significant within the multifactorial etiology of penile cancer. There was statistical significance between the lesion invasiveness and the presence of high-risk HPV infection. Thus, genotype surveillance can promote a better understanding of the role of HPV genotypes in male cancer development, and the DNA microarray assay proved to be an efficient tool for both the epidemiological study and the diagnostics of the HPV.
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Maia, Mariana Cotta, Mauro Romero Leal Passos, Vandira Maria dos Santos Pinheiro, and Roberto de Souza Salles. "Sexually transmitted diseases in women who aged 50 or older: a retrospective analysis from 2000 to 2017 in a public reference service in Niterói City, Rio de Janeiro State." In XIII Congresso da Sociedade Brasileira de DST - IX Congresso Brasileiro de AIDS - IV Congresso Latino Americano de IST/HIV/AIDS. Zeppelini Editorial e Comunicação, 2021. http://dx.doi.org/10.5327/dst-2177-8264-202133p081.

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Introduction: Sexually transmitted diseases (STDs) are more common in young people. There are few studies on STDs in the older population, particularly women. Objective: The aim of this study was to evaluate and characterize, with epidemiological variables, the prevalence of STDs in the female population over 50 years old, in a public reference service in Niterói city, Rio de Janeiro State, Brazil. Methods: The study was carried out at the STD Sector of Universidade Federal Fluminense. It was a descriptive retrospective study of quantitative character, carried out with women aged 50 years or older, attended at the aforementioned teaching, research, and extension unit, from 2000 to 2017. Data collection was performed with documentary research from the records of Sexually Transmitted Diseases Sector of Universidade Federal Fluminense. A total of 6,822 records were analyzed, of which 2,363 were of women. Of these, 50 were medical records of women over 50 years old. The variables used were age, education, marital status, use of condom, diagnosis, sexual and behavior characteristics (extramarital relationships and history of homosexuality), skin color, history of STDs, sex education, the number of sexual partners, and family income. Results: There was a higher prevalence of human papillomavirus (HPV) infection in the form of condyloma acuminata in 48% of cases and cervical intraepithelial neoplasia (CIN) I, II, or III in 20%. Syphilis occurred in 14%, genital herpes and trichomoniasis in 6% each, HIV in 4%, and gonorrhea in 2% of cases. Notably, 64% of women had no pathological history of STDs, 6% had a previous diagnosis of syphilis, and 6%, of HPV. The predominant age group was 50–59 (78%), with a higher prevalence in white women (54%). Most patients (66%) reported having one fixed partner, were married (54%), and had no history of extramarital relationships (64%). In addition, 64% of patients had no degree of sex education and 56% lived on less than two minimum wages. Most patients (78%) reported not using condoms. In 50% of cases, the level of education was incomplete primary education and only 8% had concluded higher education. Conclusion: STDs were more frequent in white women who did not use condoms. The most prevalent STD was HPV infection, as condyloma acuminata in pardo women. HPV infection as a cervical intraepithelial neoplasia (CIN) was the second most common STD in white and pardo women.
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Reports on the topic "Papillomaviruses Diagnosis"

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Wang, Huanhuan, Yuyu Zhang, Wei Bai, Bin Wang, Jinlong Wei, Ji Rui, Ying Xin, Lihua Dong, and Xin Jiang. Feasibility of immunohistochemical p16 staining in the diagnosis of human papillomavirus infection in patients with squamous cell carcinoma of the head and neck: A systematic review and meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, July 2020. http://dx.doi.org/10.37766/inplasy2020.7.0068.

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