Academic literature on the topic 'Pancreatic cancer, Radiofrequency ablation, immunity'

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Journal articles on the topic "Pancreatic cancer, Radiofrequency ablation, immunity"

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Jarosova, Jana, Peter Macinga, Lenka Krupickova, Martina Fialova, Alzbeta Hujova, Jan Mares, Ondrej Urban, et al. "Impact of Endoluminal Radiofrequency Ablation on Immunity in Pancreatic Cancer and Cholangiocarcinoma." Biomedicines 10, no. 6 (June 6, 2022): 1331. http://dx.doi.org/10.3390/biomedicines10061331.

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Radiofrequency ablation (RFA) is a mini-invasive loco-regional ablation technique that is increasingly being used as a palliative treatment for pancreatic cancer and cholangiocarcinoma. Ablation-triggered immune system stimulation has been proposed as a mechanism behind the systemic effects of RFA. The aim of our study was to investigate the immune response to endoluminal biliary RFA. Peripheral blood samples were collected from patients with pancreatic cancer and cholangiocarcinoma randomised to receive endoluminal biliary radiofrequency ablation + stent (19 patients) or stent only (21 patients). We observed an early increase in IL-6 levels and a delayed increase in CXCL1, CXCL5, and CXCL11 levels as well as an increase in CD8+ and NK cells. However, these changes were not specific to RFA treatment. Explicitly in response to RFA, we observed a delayed increase in serum CXCL1 levels and an early decrease in the number of anti-inflammatory CD206+ blood monocytes. Our study provides the first evidence of endoluminal biliary RFA-based regulation of the systemic immune response in patients with pancreatic cancer and cholangiocarcinoma. These changes were characterised by a general inflammatory response. RFA-specific activation of the adaptive immune system was not confirmed.
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Giardino, A., R. Girelli, I. Frigerio, P. Regi, F. Scopelliti, O. Perbellini, G. Innamorti, M. Bacchion, P. Pederzoli, and C. Bassi. "Immunity stimulation after radiofrequency ablation of locally advanced pancreatic cancer: Preliminary results." HPB 18 (April 2016): e760. http://dx.doi.org/10.1016/j.hpb.2016.01.265.

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Hadjicostas, P., N. Malakounides, C. Varianos, E. Kitiris, F. Lerni, and P. Symeonides. "Radiofrequency ablation in pancreatic cancer." HPB 8, no. 1 (February 2006): 61–64. http://dx.doi.org/10.1080/13651820500466673.

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Sarno, Alessandro, Alessandro Beleù, Riccardo De Robertis, Gabriele Giannotti, Giorgia Tedesco, Salvatore Paiella, and Mirko D'Onofrio. "Radiofrequency Ablation of Pancreatic Cancer." Digestive Disease Interventions 03, no. 02 (May 10, 2019): 133–37. http://dx.doi.org/10.1055/s-0039-1688437.

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AbstractRadiofrequency ablation (RFA) is emerging as a safe and feasible technique to treat various pancreatic lesions. In particular, pancreatic ductal adenocarcinoma (PDAC) is the most frequent treated lesion. Nowadays, PDAC treatment by means of RFA is limited to locally advanced, non-resectable, but non-metastatic lesions. The aim of this article is to describe the RFA technique, its results and possible complications.
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Hlavsa, J., V. Procházka, Z. Kala, T. Andrašina, B. Hemmelová, T. Pavlík, I. Penka, et al. "Radiofrequency ablation of pancreatic cancer." Pancreatology 12, no. 6 (November 2012): 586. http://dx.doi.org/10.1016/j.pan.2012.11.287.

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Chen, Sheng-Yang, and Xiao-Yong Li. "Radiofrequency ablation for unresectable pancreatic cancer." World Chinese Journal of Digestology 21, no. 31 (2013): 3383. http://dx.doi.org/10.11569/wcjd.v21.i31.3383.

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Logue, Jennifer, Edward Leen, Susan J. Moug, Ross Carter, and Colin McKay. "M1550 Radiofrequency Ablation of Locally Advanced Pancreatic Cancer." Gastroenterology 134, no. 4 (April 2008): A—871. http://dx.doi.org/10.1016/s0016-5085(08)64082-2.

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Giardino, A., G. Innamorati, R. Girelli, I. Frigerio, P. Regi, F. Scopelliti, S. Paiella, P. Pederzoli, C. Bassi, and G. Butturini. "Radiofrequency ablation of locally advanced pancreatic cancer: immunostimulation patterns." HPB 21 (2019): S977—S978. http://dx.doi.org/10.1016/j.hpb.2019.10.1287.

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Giardino, A., G. Innamorati, R. Girelli, I. Frigerio, P. Regi, F. Scopelliti, S. Paiella, P. Pederzoli, C. Bassi, and G. Butturini. "Radiofrequency ablation of Locally Advanced Pancreatic Cancer: Immunostimulation Patterns." HPB 21 (2019): S766. http://dx.doi.org/10.1016/j.hpb.2019.10.1523.

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Zou, Yi-Ping. "Intraoperative radiofrequency ablation combined with125iodine seed implantation for unresectable pancreatic cancer." World Journal of Gastroenterology 16, no. 40 (2010): 5104. http://dx.doi.org/10.3748/wjg.v16.i40.5104.

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Book chapters on the topic "Pancreatic cancer, Radiofrequency ablation, immunity"

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Ji, Jiansong. "Radiofrequency and microwave ablation for pancreatic cancer." In Integrative Pancreatic Intervention Therapy, 341–48. Elsevier, 2021. http://dx.doi.org/10.1016/b978-0-12-819402-7.00013-9.

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Conference papers on the topic "Pancreatic cancer, Radiofrequency ablation, immunity"

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"Clinical application of radiofrequency ablation in the treatment of unresectable pancreatic cancer." In The 2nd World Conference on Humanities and Social Sciences. Francis Academic Press, 2018. http://dx.doi.org/10.25236/wchss.2017.02.

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Biasutto, D., S. Stigliano, F. Covotta, and FMD Matteo. "ENDOSCOPIC ULTRASOUND-GUIDED RADIOFREQUENCY ABLATION OF PANCREATIC METASTASIS FROM RENAL CELL CANCER: FEASIBILITY AND SAFETY." In ESGE Days. © Georg Thieme Verlag KG, 2020. http://dx.doi.org/10.1055/s-0040-1704984.

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Hanks, Bradley, Mary Frecker, and Matthew Moyer. "Optimization of a Compliant Endoscopic Radiofrequency Ablation Electrode." In ASME 2017 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. American Society of Mechanical Engineers, 2017. http://dx.doi.org/10.1115/detc2017-67357.

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Radiofrequency ablation (RFA) is a common cancer treatment modality for patients who are ineligible for open surgery. There is a need for RFA electrodes that generate heating zones that closely match the geometry of typical tumors, especially for endoscopic ultrasound-guided (EUS) RFA. In this paper, the procedure for optimization of an RFA electrode is presented. First, a novel compliant electrode design is proposed. Next, a thermal ablation model is developed to predict the ablation zone surrounding an RFA electrode in biological tissue. Then, a multi-objective genetic algorithm is used to optimize two cases of the electrode geometry to match the region of destructed tissue to a spherical tumor of specified diameter. This optimization procedure is applied to an EUS-RFA ablation of pancreatic tissue. For a target 2.5cm spherical tumor, the optimal design parameters of the compliant electrode design were found. After simulating 40 generations of 50 designs per generation, both cases converged to optimal solutions. The objective functions were useful for simple electrode designs. For more complex electrode designs, the objective functions were unable to direct the design toward a 2.5cm sphere. The results of the optimization demonstrate how computational models combined with optimization can be used for systematic design of ablation electrodes. The optimization procedure may be applied to RFA of various tissue types for systematic design of electrodes that generate spherical ablation zones.
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Hanks, Bradley W., Mary Frecker, and Matthew Moyer. "Design of a Compliant Endoscopic Ultrasound-Guided Radiofrequency Ablation Probe." In ASME 2016 International Design Engineering Technical Conferences and Computers and Information in Engineering Conference. American Society of Mechanical Engineers, 2016. http://dx.doi.org/10.1115/detc2016-59923.

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Pancreatic cancer is one of the most deadly forms of cancer in the United States. Due to its late diagnosis, only 20% of patients diagnosed with the disease are eligible for surgical resection which is considered the preferred method of treatment. Radiofrequency ablation is a common cancer treatment modality for patients ineligible for open surgery. There is a lack of ablation probes which may be used to generate spherical heating zones which closely match the geometry of typical tumors. In particular, there are no endoscopic ablation probes commercially available in the United States. In this paper the design of a compliant endoscopic radiofrequency ablation probe is presented. This probe features an array of compliant tines which deploy through the cancerous tissue to effectively broaden the ablation zone. A thermal ablation model is used to inform the design of the geometry of the probe. In addition, finite element analysis is used to determine the feasibility of the compliant structures. These design tools are used as aids to inform the design and direct modifications toward a feasible probe which generates a spherical ablation zone.
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Tiankanon, Kasenee, Pradermchai Kongkam, Thanawat Luangsukrerk, Virote Sriuranpong, Chonnipa Nantavithya, Trirat Jantarattana, Arlyn Canones, et al. "IDDF2019-ABS-0171 EUS-Guided radiofrequency ablation as adjunctive treatment for unresectable pancreatic cancer versus chemotherapy alone (ERAP)." In International Digestive Disease Forum (IDDF) 2019, Hong Kong, 8–9 June 2019. BMJ Publishing Group Ltd and British Society of Gastroenterology, 2019. http://dx.doi.org/10.1136/gutjnl-2019-iddfabstracts.179.

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Tiankanon, K., P. Kongkam, T. Orprayoon, T. Luangsukrerk, DW Seo, V. Sriuranpong, C. Nantavithya, et al. "EUS-GUIDED RADIOFREQUENCY ABLATION PLUS CHEMOTHERAPY VERSUS CHEMOTHERAPY ALONE FOR UNRESECTABLE PANCREATIC CANCER (ERAP): PRELIMINARY RESULTS OF A PROSPECTIVE COMPARATIVE STUDY." In ESGE Days 2019. Georg Thieme Verlag KG, 2019. http://dx.doi.org/10.1055/s-0039-1681343.

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