Relevant bibliographies by topics / Pancreas Organogenesis

Academic literature on the topic 'Pancreas Organogenesis'

Author: Grafiati
Published: 10 December 2022
Last updated: 28 January 2023

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Journal articles on the topic "Pancreas Organogenesis"

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Hammerman, Marc R. "Organogenesis of the endocrine pancreas." Kidney International 68, no. 5 (November 2005): 1953–55. http://dx.doi.org/10.1111/j.1523-1755.2005.00628.x.

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Grapin-Botton, A. "Three-dimensional pancreas organogenesis models." Diabetes, Obesity and Metabolism 18 (September 2016): 33–40. http://dx.doi.org/10.1111/dom.12720.

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McLin, Valerie A., and Aaron M. Zorn. "Organogenesis: Making Pancreas from Liver." Current Biology 13, no. 3 (February 2003): R96—R98. http://dx.doi.org/10.1016/s0960-9822(03)00036-8.

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Gnatenko, D. A., E. P. Kopantzev, and E. D. Sverdlov. "Fibroblast growth factors and their effects in pancreas organogenesis." Biomeditsinskaya Khimiya 63, no. 3 (2017): 211–18. http://dx.doi.org/10.18097/pbmc20176303211.

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Fibroblast growth factors (FGF) – growth factors that regulate many important biological processes, including proliferation and differentiation of embryonic cells during organogenesis. In this review, we will summarize current information about the involvement of FGFs in the pancreas organogenesis. Pancreas organogenesis is a complex process, which involves constant signaling from mesenchymal tissue. This orchestrates the activation of various regulator genes at specific stages, determining the specification of progenitor cells. Alterations in FGF/FGFR signaling pathway during this process lead to incorrect activation of the master genes, which leads to different pathologies during pancreas development. Understanding the full picture about role of FGF factors in pancreas development will make it possible to more accurately understand their role in other pathologies of this organ, including carcinogenesis.
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Hammerman, Marc R. "Organogenesis of Kidney and Endocrine Pancreas." Organogenesis 3, no. 2 (October 2007): 59–66. http://dx.doi.org/10.4161/org.3.2.5382.

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Gnatenko, D. A., E. P. Kopantsev, and E. D. Sverdlov. "Fibroblast growth factors and pancreas organogenesis." Biochemistry (Moscow), Supplement Series B: Biomedical Chemistry 11, no. 4 (October 2017): 341–48. http://dx.doi.org/10.1134/s1990750817040023.

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Cano, David A., Bernat Soria, Francisco Martín, and Anabel Rojas. "Transcriptional control of mammalian pancreas organogenesis." Cellular and Molecular Life Sciences 71, no. 13 (November 13, 2013): 2383–402. http://dx.doi.org/10.1007/s00018-013-1510-2.

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Kim, Seung K., Matthias Hebrok, En Li, S. Paul Oh, Heinrich Schrewe, Erin B. Harmon, Joon S. Lee, and Douglas A. Melton. "Activin receptor patterning of foregut organogenesis." Genes & Development 14, no. 15 (August 1, 2000): 1866–71. http://dx.doi.org/10.1101/gad.14.15.1866.

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Foregut development produces a characteristic sequence of gastrointestinal and respiratory organs, but the signaling pathways that ensure this developmental order remain largely unknown. Here, mutations of activin receptors ActRIIA and ActRIIB are shown to disrupt the development of posterior foregut-derived organs, including the stomach, pancreas, and spleen. Foregut expression of genes includingShh and Isl1 is shifted in mutant mice. The endocrine pancreas is particularly sensitive to the type and extent of receptor inactivation. ActRIIA+/−B+/−animals lack axial defects, but have hypoplastic pancreatic islets, hypoinsulinemia, and impaired glucose tolerance. Thus, activin receptor-mediated signaling regulates axial patterning, cell differentiation, and function of foregut-derived organs.
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Carrasco, Manuel, Irene Delgado, Bernat Soria, Francisco Martín, and Anabel Rojas. "GATA4 and GATA6 control mouse pancreas organogenesis." Journal of Clinical Investigation 122, no. 10 (October 1, 2012): 3504–15. http://dx.doi.org/10.1172/jci63240.

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Shih, Hung Ping, Allen Wang, and Maike Sander. "Pancreas Organogenesis: From Lineage Determination to Morphogenesis." Annual Review of Cell and Developmental Biology 29, no. 1 (October 6, 2013): 81–105. http://dx.doi.org/10.1146/annurev-cellbio-101512-122405.

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Dissertations / Theses on the topic "Pancreas Organogenesis"

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Hirata, Koji. "Exocrine tissue-driven TFF2 prevents apoptotic cell death of endocrine lineage during pancreas organogenesis." Kyoto University, 2019. http://hdl.handle.net/2433/243273.

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Guerrero, Zayas Mara Isel. "Designing New Approaches for the Study of Early Murine Endodermal Organogenesis using Whole Embryo Culture." 2011. https://scholarworks.umass.edu/theses/561.

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This thesis investigates the applicability of novel approaches designed to study the molecular mechanisms required for the initiation of organogenesis within the early endoderm. The endoderm is the germ layer that gives rise to the gut-tube and associated organs including the thyroid, lung, liver and pancreas. Our laboratory focuses on understanding the molecular mechanisms governing the developmental transition from endoderm to liver and pancreas. Several signaling pathways including Wnt, Retinoic Acid (RA), Bone Morphogenetic Protein (BMP) and Transforming Growth Factor-β (TGFβ) have been implicated in the emergence of the liver bud from the endoderm in the mouse or other vertebrate species. However, neither the exact signals nor the precise roles during budding process have been identified, due to the complexity of specifically altering these essential pathways using traditional genetic approaches during the earliest stages of endoderm organogenesis. These traditional techniques include transgenic, knockout or conditional knockouts strategies. To overcome the difficulties of genetic accessibility, our laboratory has optimized two complementary approaches, electroporation and addition of activators or inhibitors directly to the culture media, to study the earliest stages of organ formation using an ex vivo culture system (whole embryo culture), that allow us for normal embryonic development for up to two days. This ex-vivo technique also provides the opportunity to access and manipulate the endoderm, specifically the liver and pancreas precursor cells, prior to organ specification. Because the endoderm undergoes normal liver and pancreas specification in our ex vivo system by 24 hours after culture begin, we reason that it is possible to manipulate gene expression at the onset of culture. We then determine the effects of this manipulation on liver or pancreas development by molecular and morphological analysis after culture. The first approach we developed is the use of directional electroporation of nucleic acids to manipulate a specific region of the endoderm, particularly on liver and pancreas developmental processes. The second method is global inhibition or activation using inhibitors or growth factors activators, focusing on the TGFβ signaling pathway. These techniques will be performed prior to, or concurrent with, liver and pancreas specification, followed by embryo culture until after the onset of organogenesis. The combination of these techniques constitutes a practical approach to stage-manage the endoderm in a temporally and spatially distinct manner. In addition, it will allow us to alter specific signaling pathways without the labor-intensive generation of genetically modified animals. Indeed, establishment of these methodologies may provide a robust tool for rapid screening of candidate genes and signaling molecules underlying organogenesis in any endodermally derived organ in mouse embryos.
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Brink, Christopher. "Struktur- und Funktionsanalysen des Pax4-Promotors." Doctoral thesis, 2002. http://hdl.handle.net/11858/00-1735-0000-0006-ABEE-6.

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Book chapters on the topic "Pancreas Organogenesis"

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Karamitopoulou-Diamantis, Eva, and Beat Gloor. "Embryogenesis and Organogenesis of the Pancreas." In Pathology of the Pancreas, 62–66. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-030-62416-3_5536.

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Karamitopoulou-Diamantis, Eva, and Beat Gloor. "Embryogenesis and Organogenesis of the Pancreas." In Encyclopedia of Pathology, 1–5. Cham: Springer International Publishing, 2021. http://dx.doi.org/10.1007/978-3-319-28845-1_5536-1.

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Cozzitorto, Corinna, and Francesca M. Spagnoli. "Pancreas organogenesis: The interplay between surrounding microenvironment(s) and epithelium-intrinsic factors." In Current Topics in Developmental Biology, 221–56. Elsevier, 2019. http://dx.doi.org/10.1016/bs.ctdb.2018.12.005.

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You might also be interested in the extended bibliographies on the topic 'Pancreas Organogenesis' for particular source types:
Journal articles
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