Academic literature on the topic 'P84 adaptor subunit of PI3Kγ'
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Journal articles on the topic "P84 adaptor subunit of PI3Kγ"
Rathinaswamy, Manoj K., Udit Dalwadi, Kaelin D. Fleming, Carson Adams, Jordan T. B. Stariha, Els Pardon, Minkyung Baek, et al. "Structure of the phosphoinositide 3-kinase (PI3K) p110γ-p101 complex reveals molecular mechanism of GPCR activation." Science Advances 7, no. 35 (August 2021): eabj4282. http://dx.doi.org/10.1126/sciadv.abj4282.
Full textGeering, B., P. R. Cutillas, and B. Vanhaesebroeck. "Regulation of class IA PI3Ks: is there a role for monomeric PI3K subunits?" Biochemical Society Transactions 35, no. 2 (March 20, 2007): 199–203. http://dx.doi.org/10.1042/bst0350199.
Full textRynkiewicz, Natalie K., Karen E. Anderson, Sabine Suire, Daniel M. Collins, Eleftherios Karanasios, Oscar Vadas, Roger Williams, et al. "Gβγ is a direct regulator of endogenous p101/p110γ and p84/p110γ PI3Kγ complexes in mouse neutrophils." Science Signaling 13, no. 656 (November 3, 2020): eaaz4003. http://dx.doi.org/10.1126/scisignal.aaz4003.
Full textShymanets, Aliaksei, Mohammad R. Ahmadian, Katja T. Kössmeier, Reinhard Wetzker, Christian Harteneck, and Bernd Nürnberg. "The p101 subunit of PI3Kγ restores activation by Gβ mutants deficient in stimulating p110γ." Biochemical Journal 441, no. 3 (January 16, 2012): 851–58. http://dx.doi.org/10.1042/bj20111664.
Full textFox, Millie, Helen R. Mott, and Darerca Owen. "Class IA PI3K regulatory subunits: p110-independent roles and structures." Biochemical Society Transactions 48, no. 4 (July 17, 2020): 1397–417. http://dx.doi.org/10.1042/bst20190845.
Full textWilson, Lindsay S., George S. Baillie, Lisa M. Pritchard, Bibiana Umana, Anna Terrin, Manuela Zaccolo, Miles D. Houslay, and Donald H. Maurice. "A Phosphodiesterase 3B-based Signaling Complex Integrates Exchange Protein Activated by cAMP 1 and Phosphatidylinositol 3-Kinase Signals in Human Arterial Endothelial Cells." Journal of Biological Chemistry 286, no. 18 (March 10, 2011): 16285–96. http://dx.doi.org/10.1074/jbc.m110.217026.
Full textGu, Haihua, Roberto J. Botelho, Min Yu, Sergio Grinstein, and Benjamin G. Neel. "Critical role for scaffolding adapter Gab2 in FcγR-mediated phagocytosis." Journal of Cell Biology 161, no. 6 (June 23, 2003): 1151–61. http://dx.doi.org/10.1083/jcb.200212158.
Full textGeng, Jian-Guo, Hai-Bo Wang, Ming Chen, Tao Xu, Lei Zhang, Xueliang Zhu, and Edward F. Plow. "P-Selectin Activates Leukocyte Integrin alphaMbeta2 by Recruiting Phosphatidylinositol-3 Kinase to P-Selectin Glycoprotein Ligand-1 Cytoplasmic Domain through Adaptor Protein Naf1." Blood 104, no. 11 (November 16, 2004): 652. http://dx.doi.org/10.1182/blood.v104.11.652.652.
Full textCarpentier, Samuel J., Minjian Ni, Jeffrey M. Duggan, Richard G. James, Brad T. Cookson, and Jessica A. Hamerman. "The signaling adaptor BCAP inhibits NLRP3 and NLRC4 inflammasome activation in macrophages through interactions with Flightless-1." Science Signaling 12, no. 581 (May 14, 2019): eaau0615. http://dx.doi.org/10.1126/scisignal.aau0615.
Full textHe, Xiao, Hu Dai, Xiaomin Wang, David Skidmore, Tomohiro Kurosaki, and Peter E. Jensen. "BCAP (B-cell adaptor for phosphoinositide 3-kinase) plays a role in development of Marginal Zone B cells in mice." Journal of Immunology 196, no. 1_Supplement (May 1, 2016): 122.9. http://dx.doi.org/10.4049/jimmunol.196.supp.122.9.
Full textDissertations / Theses on the topic "P84 adaptor subunit of PI3Kγ"
Turvey, Michelle Elizabeth. "The role and regulation of the p84 adaptor subunit in phosphatidylinositol 3-kinase γ lipid-kinase signalling and the control of PI3Kγ-dependent cell migration." Thesis, 2015. http://hdl.handle.net/2440/111403.
Full textThesis (Ph.D.) -- University of Adelaide, School of Biological Sciences, 2015.