Journal articles on the topic 'P53-regulated genes'
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Keegan, Lunec, and Neal. "p53 and p53-regulated genes in bladder cancer." BJU International 82, no. 5 (November 1998): 710–20. http://dx.doi.org/10.1046/j.1464-410x.1998.00822.x.
Full textXu, H., and M. R. El-Gewely. "P53 network — its downstream regulated genes." Biochemical Society Transactions 28, no. 5 (October 1, 2000): A227. http://dx.doi.org/10.1042/bst028a227a.
Full textKlingler, H. Christoph. "p53 and p53 regulated genes in bladder cancer [review]." Current Opinion in Urology 9, no. 2 (March 1999): 172. http://dx.doi.org/10.1097/00042307-199903000-00015.
Full textRiley, Todd, Eduardo Sontag, Patricia Chen, and Arnold Levine. "Transcriptional control of human p53-regulated genes." Nature Reviews Molecular Cell Biology 9, no. 5 (May 2008): 402–12. http://dx.doi.org/10.1038/nrm2395.
Full textYu, J., L. Zhang, P. M. Hwang, C. Rago, K. W. Kinzler, and B. Vogelstein. "Identification and classification of p53-regulated genes." Proceedings of the National Academy of Sciences 96, no. 25 (December 7, 1999): 14517–22. http://dx.doi.org/10.1073/pnas.96.25.14517.
Full textLotem, J., H. Gal, R. Kama, N. Amariglio, G. Rechavi, E. Domany, L. Sachs, and D. Givol. "Inhibition of p53-induced apoptosis without affecting expression of p53-regulated genes." Proceedings of the National Academy of Sciences 100, no. 11 (May 12, 2003): 6718–23. http://dx.doi.org/10.1073/pnas.1031695100.
Full textFiordaliso, F., A. Leri, D. Cesselli, F. Limana, B. Safai, B. Nadal-Ginard, P. Anversa, and J. Kajstura. "Hyperglycemia Activates p53 and p53-Regulated Genes Leading to Myocyte Cell Death." Diabetes 50, no. 10 (October 1, 2001): 2363–75. http://dx.doi.org/10.2337/diabetes.50.10.2363.
Full textWang, Chao, Cui Rong Teo, and Kanaga Sabapathy. "p53-Related Transcription Targets of TAp73 in Cancer Cells—Bona Fide or Distorted Reality?" International Journal of Molecular Sciences 21, no. 4 (February 17, 2020): 1346. http://dx.doi.org/10.3390/ijms21041346.
Full textZhao, Renbin, Kurt Gish, Maureen Murphy, Yuxin Yin, Daniel Notterman, William H. Hoffman, Edward Tom, David H. Mack, and Arnold J. Levine. "Analysis of p53-regulated gene expression patterns using oligonucleotide arrays." Genes & Development 14, no. 8 (April 15, 2000): 981–93. http://dx.doi.org/10.1101/gad.14.8.981.
Full textŁasut-Szyszka, Barbara, Beata Małachowska, Agnieszka Gdowicz-Kłosok, Małgorzata Krześniak, Magdalena Głowala-Kosińska, Artur Zajkowicz, and Marek Rusin. "Transcriptome Analysis of Cells Exposed to Actinomycin D and Nutlin-3a Reveals New Candidate p53-Target Genes and Indicates That CHIR-98014 Is an Important Inhibitor of p53 Activity." International Journal of Molecular Sciences 22, no. 20 (October 14, 2021): 11072. http://dx.doi.org/10.3390/ijms222011072.
Full textDal-Bo, Michele, Paola Secchiero, Massimo Degan, Riccardo Bomben, Dania Benedetti, Antonella Zucchetto, Daniela Marconi, et al. "B-Cell Chronic Lymphocytic Leukemia Cells Exposed to the Non-Genotoxic p53 Activator Nutlin-3 Are Characterized by a Specific Gene Expression Signature." Blood 114, no. 22 (November 20, 2009): 4374. http://dx.doi.org/10.1182/blood.v114.22.4374.4374.
Full textLi, Yuwen, Jiao Liu, Nathan McLaughlin, Dimcho Bachvarov, Zubaida Saifudeen, and Samir S. El-Dahr. "Genome-wide analysis of the p53 gene regulatory network in the developing mouse kidney." Physiological Genomics 45, no. 20 (October 15, 2013): 948–64. http://dx.doi.org/10.1152/physiolgenomics.00113.2013.
Full textKim, Jung-Sik, Carolyn Lee, Challice L. Bonifant, Habtom Ressom, and Todd Waldman. "Activation of p53-Dependent Growth Suppression in Human Cells by Mutations in PTEN or PIK3CA." Molecular and Cellular Biology 27, no. 2 (October 23, 2006): 662–77. http://dx.doi.org/10.1128/mcb.00537-06.
Full textKadioglu, Onat, Mohamed Saeed, Nuha Mahmoud, Shaymaa Azawi, Kristin Mrasek, Thomas Liehr, and Thomas Efferth. "Identification of potential novel drug resistance mechanisms by genomic and transcriptomic profiling of colon cancer cells with p53 deletion." Archives of Toxicology 95, no. 3 (January 30, 2021): 959–74. http://dx.doi.org/10.1007/s00204-021-02979-4.
Full textZhang, Cong, Jiangfei Zhou, Shengnan Li, Kairui Cai, Xiangling Guo, Chengshui Liao, and Chen Wang. "Bursal Hexapeptide, A Potential Immunomodulator, Inhibits Tumor Cells Proliferation via p53 Signaling Pathway." Anti-Cancer Agents in Medicinal Chemistry 18, no. 11 (January 28, 2019): 1582–88. http://dx.doi.org/10.2174/1871520618666180604094618.
Full textGong, Lili, Fangyuan Liu, Zhen Xiong, Ruili Qi, Zhongwen Luo, Xiaodong Gong, Qian Nie, et al. "Heterochromatin protects retinal pigment epithelium cells from oxidative damage by silencing p53 target genes." Proceedings of the National Academy of Sciences 115, no. 17 (April 5, 2018): E3987—E3995. http://dx.doi.org/10.1073/pnas.1715237115.
Full textMiyajima, Chiharu, Yuki Kawarada, Yasumichi Inoue, Chiaki Suzuki, Kana Mitamura, Daisuke Morishita, Nobumichi Ohoka, Takeshi Imamura, and Hidetoshi Hayashi. "Transcriptional Coactivator TAZ Negatively Regulates Tumor Suppressor p53 Activity and Cellular Senescence." Cells 9, no. 1 (January 9, 2020): 171. http://dx.doi.org/10.3390/cells9010171.
Full textZhang, Ying, Collin Dube, Myron Gibert, Nichola Cruickshanks, Baomin Wang, Maeve Coughlan, Yanzhi Yang, et al. "The p53 Pathway in Glioblastoma." Cancers 10, no. 9 (September 1, 2018): 297. http://dx.doi.org/10.3390/cancers10090297.
Full textFriedlander, P., Y. Haupt, C. Prives, and M. Oren. "A mutant p53 that discriminates between p53-responsive genes cannot induce apoptosis." Molecular and Cellular Biology 16, no. 9 (September 1996): 4961–71. http://dx.doi.org/10.1128/mcb.16.9.4961.
Full textNigro, J. M., R. Sikorski, S. I. Reed, and B. Vogelstein. "Human p53 and CDC2Hs genes combine to inhibit the proliferation of Saccharomyces cerevisiae." Molecular and Cellular Biology 12, no. 3 (March 1992): 1357–65. http://dx.doi.org/10.1128/mcb.12.3.1357-1365.1992.
Full textNigro, J. M., R. Sikorski, S. I. Reed, and B. Vogelstein. "Human p53 and CDC2Hs genes combine to inhibit the proliferation of Saccharomyces cerevisiae." Molecular and Cellular Biology 12, no. 3 (March 1992): 1357–65. http://dx.doi.org/10.1128/mcb.12.3.1357.
Full textLou, Guohua, Yanning Liu, Shanshan Wu, Jihua Xue, Fan Yang, Haijing Fu, Min Zheng, and Zhi Chen. "The p53/miR-34a/SIRT1 Positive Feedback Loop in Quercetin-Induced Apoptosis." Cellular Physiology and Biochemistry 35, no. 6 (2015): 2192–202. http://dx.doi.org/10.1159/000374024.
Full textKukita, Asako, Kenbun Sone, Syuzo Kaneko, Eiryo Kawakami, Shinya Oki, Machiko Kojima, Miku Wada, et al. "The Histone Methyltransferase SETD8 Regulates the Expression of Tumor Suppressor Genes via H4K20 Methylation and the p53 Signaling Pathway in Endometrial Cancer Cells." Cancers 14, no. 21 (October 31, 2022): 5367. http://dx.doi.org/10.3390/cancers14215367.
Full textBoehme, S. A., and M. J. Lenardo. "TCR-mediated death of mature T lymphocytes occurs in the absence of p53." Journal of Immunology 156, no. 11 (June 1, 1996): 4075–78. http://dx.doi.org/10.4049/jimmunol.156.11.4075.
Full textHannemann, Holger, Kyle Rosenke, John M. O'Dowd, and Elizabeth A. Fortunato. "The Presence of p53 Influences the Expression of Multiple Human Cytomegalovirus Genes at Early Times Postinfection." Journal of Virology 83, no. 9 (February 18, 2009): 4316–25. http://dx.doi.org/10.1128/jvi.02075-08.
Full textHearnes, Jamie M., Deborah J. Mays, Kristy L. Schavolt, Luojia Tang, Xin Jiang, and Jennifer A. Pietenpol. "Chromatin Immunoprecipitation-Based Screen To Identify Functional Genomic Binding Sites for Sequence-Specific Transactivators." Molecular and Cellular Biology 25, no. 22 (November 15, 2005): 10148–58. http://dx.doi.org/10.1128/mcb.25.22.10148-10158.2005.
Full textQiao, X., H. Wang, X. Wang, B. Zhao, and J. Liu. "Microarray technology reveals potentially novel genes and pathways involved in non-functioning pituitary adenomas." Balkan Journal of Medical Genetics 19, no. 2 (December 31, 2016): 5–16. http://dx.doi.org/10.1515/bjmg-2016-0030.
Full textWu, Chiao-En, Chen-Yang Huang, Chiao-Ping Chen, Yi-Ru Pan, John Wen-Cheng Chang, Jen-Shi Chen, Chun-Nan Yeh, and John Lunec. "WIP1 Inhibition by GSK2830371 Potentiates HDM201 through Enhanced p53 Phosphorylation and Activation in Liver Adenocarcinoma Cells." Cancers 13, no. 15 (July 31, 2021): 3876. http://dx.doi.org/10.3390/cancers13153876.
Full textLing, Xiaoyang, Ye Chen, Peter P. Ruvolo, Vivian Ruvolo, Zhiqiang Wang, Min Zhang, Yuexi Shi, Marina Konopleva, Richard E. Davis, and Michael Andreeff. "Unique Effects of p53−/− Leukemic Cells On Mesenchymal Stromal Cell Gene Expression Profile in Vitro." Blood 120, no. 21 (November 16, 2012): 3468. http://dx.doi.org/10.1182/blood.v120.21.3468.3468.
Full textMenendez, Daniel, Alberto Inga, and Michael A. Resnick. "The Biological Impact of the Human Master Regulator p53 Can Be Altered by Mutations That Change the Spectrum and Expression of Its Target Genes." Molecular and Cellular Biology 26, no. 6 (March 15, 2006): 2297–308. http://dx.doi.org/10.1128/mcb.26.6.2297-2308.2006.
Full textSzak, Suzanne T., Deborah Mays, and Jennifer A. Pietenpol. "Kinetics of p53 Binding to Promoter Sites In Vivo." Molecular and Cellular Biology 21, no. 10 (May 15, 2001): 3375–86. http://dx.doi.org/10.1128/mcb.21.10.3375-3386.2001.
Full textTassabehji, Nadine M., Jacob W. Vanlandingham, and Cathy W. Levenson. "Copper Alters the Conformation and Transcriptional Activity of the Tumor Suppressor Protein p53 in Human Hep G2 Cells." Experimental Biology and Medicine 230, no. 10 (November 2005): 699–708. http://dx.doi.org/10.1177/153537020523001002.
Full textKannan, Karuppiah, Ninette Amariglio, Gideon Rechavi, Yasmin Yaakov, Naftali Kaminski, Gad Getz, Eitan Domany, and David Givol. "Primary and secondary target genes regulated by p53 identified by DNA microarrays." Nature Genetics 27, S4 (April 2001): 63. http://dx.doi.org/10.1038/87146.
Full textKannan, Karuppiah, Ninette Amariglio, Gideon Rechavi, Jasmine Jakob-Hirsch, Itai Kela, Naftali Kaminski, Gad Getz, Eytan Domany, and David Givol. "DNA microarrays identification of primary and secondary target genes regulated by p53." Oncogene 20, no. 18 (April 2001): 2225–34. http://dx.doi.org/10.1038/sj.onc.1204319.
Full textArizti, Paz, Li Fang, Iha Park, Yuxin Yin, Ellen Solomon, Toru Ouchi, Stuart A. Aaronson, and Sam W. Lee. "Tumor Suppressor p53 Is Required To Modulate BRCA1 Expression." Molecular and Cellular Biology 20, no. 20 (October 15, 2000): 7450–59. http://dx.doi.org/10.1128/mcb.20.20.7450-7459.2000.
Full textKim, Bu-Yeo, Seo-Young Lee, and Sun-Ku Chung. "Differential Transcriptional Regulation of Polymorphic p53 Codon 72 in Metabolic Pathways." International Journal of Molecular Sciences 22, no. 19 (October 6, 2021): 10793. http://dx.doi.org/10.3390/ijms221910793.
Full textGüttler, Antje, Claus Weinholdt, Elisabeth Ruff, Judith Reidt, Elisa Darnstaedt, Alicia Wildemann, Marina Petrenko, et al. "SESN2 Knockdown Increases Betulinic Acid-Induced Radiosensitivity of Hypoxic Breast Cancer Cells." Cells 12, no. 1 (December 31, 2022): 177. http://dx.doi.org/10.3390/cells12010177.
Full textChoisy-Rossi, Caroline, Philippe Reisdorf, and Elisheva Yonish-Rouach. "Mechanisms of p53-induced apoptosis: in search of genes which are regulated during p53-mediated cell death." Toxicology Letters 102-103 (December 1998): 491–96. http://dx.doi.org/10.1016/s0378-4274(98)00238-0.
Full textTaylor, Alison M., Jessica M. Humphries, Richard M. White, Ryan D. Murphey, Caroline E. Burns, and Leonard I. Zon. "p53 Dependent and Dose Dependent Effects of Rps29 Mutation In the Zebrafish Embryo." Blood 116, no. 21 (November 19, 2010): 1170. http://dx.doi.org/10.1182/blood.v116.21.1170.1170.
Full textPorrello, Alessandro, Maria Antonietta Cerone, Sabrina Coen, Aymone Gurtner, Giulia Fontemaggi, Letizia Cimino, Giulia Piaggio, Ada Sacchi, and Silvia Soddu. "P53 Regulates Myogenesis by Triggering the Differentiation Activity of Prb." Journal of Cell Biology 151, no. 6 (December 11, 2000): 1295–304. http://dx.doi.org/10.1083/jcb.151.6.1295.
Full textOkazaki, Ryuji. "Role of p53 in Regulating Radiation Responses." Life 12, no. 7 (July 21, 2022): 1099. http://dx.doi.org/10.3390/life12071099.
Full textMachida, Yuichi J., Yuefeng Chen, Yuka Machida, Ankit Malhotra, Sukumar Sarkar, and Anindya Dutta. "Targeted Comparative RNA Interference Analysis Reveals Differential Requirement of Genes Essential for Cell Proliferation." Molecular Biology of the Cell 17, no. 11 (November 2006): 4837–45. http://dx.doi.org/10.1091/mbc.e06-04-0340.
Full textFujiyama, Hiroki, Takahiro Tsuji, Kensuke Hironaka, Kazumasa Yoshida, Nozomi Sugimoto, and Masatoshi Fujita. "GRWD1 directly interacts with p53 and negatively regulates p53 transcriptional activity." Journal of Biochemistry 167, no. 1 (September 23, 2019): 15–24. http://dx.doi.org/10.1093/jb/mvz075.
Full textPustylnyak, Vladimir O., Pavel D. Lisachev, and Mark B. Shtark. "Expression of p53 Target Genes in the Early Phase of Long-Term Potentiation in the Rat Hippocampal CA1 Area." Neural Plasticity 2015 (2015): 1–12. http://dx.doi.org/10.1155/2015/242158.
Full textBrodsky, Michael H., Brian T. Weinert, Garson Tsang, Yikang S. Rong, Nadine M. McGinnis, Kent G. Golic, Donald C. Rio, and Gerald M. Rubin. "Drosophila melanogaster MNK/Chk2 and p53 Regulate Multiple DNA Repair and Apoptotic Pathways following DNA Damage." Molecular and Cellular Biology 24, no. 3 (February 1, 2004): 1219–31. http://dx.doi.org/10.1128/mcb.24.3.1219-1231.2004.
Full textShao, Wei, Zhen-Yu Hao, Yi-Fei Chen, Jun Du, Qian He, Liang-Liang Ren, Yan Gao, et al. "OIP5-AS1 specifies p53-driven POX transcription regulated by TRPC6 in glioma." Journal of Molecular Cell Biology 13, no. 6 (January 28, 2021): 409–21. http://dx.doi.org/10.1093/jmcb/mjab001.
Full textKishore, A. Hari, Kiran Batta, Chandrima Das, Shipra Agarwal, and Tapas K. Kundu. "p53 regulates its own activator: transcriptional co-activator PC4, a new p53-responsive gene." Biochemical Journal 406, no. 3 (August 29, 2007): 437–44. http://dx.doi.org/10.1042/bj20070390.
Full textDreyfus, David H., Masayuki Nagasawa, Colm A. Kelleher, and Erwin W. Gelfand. "Stable expression of Epstein-Barr virus BZLF-1–encoded ZEBRA protein activates p53-dependent transcription in human Jurkat T-lymphoblastoid cells." Blood 96, no. 2 (July 15, 2000): 625–34. http://dx.doi.org/10.1182/blood.v96.2.625.
Full textDreyfus, David H., Masayuki Nagasawa, Colm A. Kelleher, and Erwin W. Gelfand. "Stable expression of Epstein-Barr virus BZLF-1–encoded ZEBRA protein activates p53-dependent transcription in human Jurkat T-lymphoblastoid cells." Blood 96, no. 2 (July 15, 2000): 625–34. http://dx.doi.org/10.1182/blood.v96.2.625.014k27_625_634.
Full textLi, Pingxin, Hongjie Yao, Zhiqiang Zhang, Ming Li, Yuan Luo, Paul R. Thompson, David S. Gilmour, and Yanming Wang. "Regulation of p53 Target Gene Expression by Peptidylarginine Deiminase 4." Molecular and Cellular Biology 28, no. 15 (May 27, 2008): 4745–58. http://dx.doi.org/10.1128/mcb.01747-07.
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