Journal articles on the topic 'P-PBPK model'
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Mi, Kun, Shanju Pu, Yixuan Hou, Lei Sun, Kaixiang Zhou, Wenjin Ma, Xiangyue Xu, et al. "Optimization and Validation of Dosage Regimen for Ceftiofur against Pasteurella multocida in Swine by Physiological Based Pharmacokinetic–Pharmacodynamic Model." International Journal of Molecular Sciences 23, no. 7 (March 28, 2022): 3722. http://dx.doi.org/10.3390/ijms23073722.
Jeong, Yoo-Seong, Min-Soo Kim, Nora Lee, Areum Lee, Yoon-Jee Chae, Suk-Jae Chung, and Kyeong-Ryoon Lee. "Development of Physiologically Based Pharmacokinetic Model for Orally Administered Fexuprazan in Humans." Pharmaceutics 13, no. 6 (May 29, 2021): 813. http://dx.doi.org/10.3390/pharmaceutics13060813.
Dallmann, A., P. Mian, P. Annaert, M. Pfister, K. Allegaert, and J. van den Anker. "P21 PBPK modeling in pregnancy: achievements, shortcomings and future perspectives." Archives of Disease in Childhood 104, no. 6 (May 17, 2019): e25.2-e25. http://dx.doi.org/10.1136/archdischild-2019-esdppp.59.
Nauwelaerts, Nina, Julia Macente, Neel Deferm, Rodolfo Hernandes Bonan, Miao-Chan Huang, Martje Van Neste, David Bibi, et al. "Generic Workflow to Predict Medicine Concentrations in Human Milk Using Physiologically-Based Pharmacokinetic (PBPK) Modelling—A Contribution from the ConcePTION Project." Pharmaceutics 15, no. 5 (May 11, 2023): 1469. http://dx.doi.org/10.3390/pharmaceutics15051469.
Kovar, Lukas, Christina Schräpel, Dominik Selzer, Yvonne Kohl, Robert Bals, Matthias Schwab, and Thorsten Lehr. "Physiologically-Based Pharmacokinetic (PBPK) Modeling of Buprenorphine in Adults, Children and Preterm Neonates." Pharmaceutics 12, no. 6 (June 23, 2020): 578. http://dx.doi.org/10.3390/pharmaceutics12060578.
Pilla Reddy, Venkatesh, Adrian J. Fretland, Diansong Zhou, Shringi Sharma, Buyun Chen, Karthick Vishwanathan, Dermot F. McGinnity, Yan Xu, and Joseph A. Ware. "Mechanistic physiology-based pharmacokinetic modeling to elucidate vincristine-induced peripheral neuropathy following treatment with novel kinase inhibitors." Cancer Chemotherapy and Pharmacology 88, no. 3 (June 2, 2021): 451–64. http://dx.doi.org/10.1007/s00280-021-04302-5.
Yang, Yiting, Ping Li, Zexin Zhang, Zhongjian Wang, Li Liu, and Xiaodong Liu. "Prediction of Cyclosporin-Mediated Drug Interaction Using Physiologically Based Pharmacokinetic Model Characterizing Interplay of Drug Transporters and Enzymes." International Journal of Molecular Sciences 21, no. 19 (September 24, 2020): 7023. http://dx.doi.org/10.3390/ijms21197023.
Wills, Kenneth H., Stephen J. Behan, Michael J. Nance, Jessica L. Dawson, Thomas M. Polasek, Ashley M. Hopkins, Madelé van Dyk, and Andrew Rowland. "Combining Therapeutic Drug Monitoring and Pharmacokinetic Modelling Deconvolutes Physiological and Environmental Sources of Variability in Clozapine Exposure." Pharmaceutics 14, no. 1 (December 27, 2021): 47. http://dx.doi.org/10.3390/pharmaceutics14010047.
Kim, Min-Soo, Nora Lee, Areum Lee, Yoon-Jee Chae, Suk-Jae Chung, and Kyeong-Ryoon Lee. "Model-Based Prediction of Acid Suppression and Proposal of a New Dosing Regimen of Fexuprazan in Humans." Pharmaceuticals 15, no. 6 (June 3, 2022): 709. http://dx.doi.org/10.3390/ph15060709.
Bachelet, Delphine, Marc-André Verner, Monica Neri, Émilie Cordina Duverger, Corinne Charlier, Patrick Arveux, Sami Haddad, and Pascal Guénel. "Breast Cancer and Exposure to Organochlorines in the CECILE Study: Associations with Plasma Levels Measured at the Time of Diagnosis and Estimated during Adolescence." International Journal of Environmental Research and Public Health 16, no. 2 (January 18, 2019): 271. http://dx.doi.org/10.3390/ijerph16020271.
Berghausen, Joerg, Frank Hans Seiler, Nathalie Gobeau, and Bernard Faller. "Simulated rat intestinal fluid improves oral exposure prediction for poorly soluble compounds over a wide dose range." ADMET & DMPK 4, no. 1 (March 30, 2016): 35. http://dx.doi.org/10.5599/admet.4.1.258.
Liu, Rongrui, Tim R. Zacharewski, Rory B. Conolly, and Qiang Zhang. "A Physiologically Based Pharmacokinetic (PBPK) Modeling Framework for Mixtures of Dioxin-like Compounds." Toxics 10, no. 11 (November 17, 2022): 700. http://dx.doi.org/10.3390/toxics10110700.
Ciffroy, Philippe, T. Tanaka, E. Johansson, and C. Brochot. "Linking fate model in freshwater and PBPK model to assess human internal dosimetry of B(a)P associated with drinking water." Environmental Geochemistry and Health 33, no. 4 (April 2, 2011): 371–87. http://dx.doi.org/10.1007/s10653-011-9382-6.
Gaohua, Lu, Khaled Abduljalil, Masoud Jamei, Trevor N. Johnson, and Amin Rostami-Hodjegan. "A pregnancy physiologically based pharmacokinetic (p-PBPK) model for disposition of drugs metabolized by CYP1A2, CYP2D6 and CYP3A4." British Journal of Clinical Pharmacology 74, no. 5 (October 9, 2012): 873–85. http://dx.doi.org/10.1111/j.1365-2125.2012.04363.x.
Templeton, Ian E., Terry Podoll, Cecile Marie Krejsa, and J. Greg Slatter. "A Mechanistic Physiologically Based Pharmacokinetic (PBPK) Drug Interaction Model for the Mouse Double Minute 2 (MDM2) Inhibitor KRT-232." Blood 136, Supplement 1 (November 5, 2020): 9–10. http://dx.doi.org/10.1182/blood-2020-135987.
Smith, Jordan N., Kari A. Gaither, and Paritosh Pande. "Competitive Metabolism of Polycyclic Aromatic Hydrocarbons (PAHs): An Assessment Using In Vitro Metabolism and Physiologically Based Pharmacokinetic (PBPK) Modeling." International Journal of Environmental Research and Public Health 19, no. 14 (July 6, 2022): 8266. http://dx.doi.org/10.3390/ijerph19148266.
Russo, Francesca M., Felix De Bie, Ryan Hodges, Alan Flake, and Jan Deprest. "Sildenafil for Antenatal Treatment of Congenital Diaphragmatic Hernia: From Bench to Bedside." Current Pharmaceutical Design 25, no. 5 (June 3, 2019): 601–8. http://dx.doi.org/10.2174/1381612825666190320151856.
Kato, Takafumi, Tsuyoshi Mikkaichi, Yasushi Yoshigae, Noriko Okudaira, Takako Shimizu, Takashi Izumi, Shuichi Ando, and Yoshiaki Matsumoto. "Quantitative analysis of an impact of P-glycoprotein on edoxaban's disposition using a human physiologically based pharmacokinetic (PBPK) model." International Journal of Pharmaceutics 597 (March 2021): 120349. http://dx.doi.org/10.1016/j.ijpharm.2021.120349.
Verscheijden, Laurens F. M., Jan B. Koenderink, Saskia N. de Wildt, and Frans G. M. Russel. "Differences in P-glycoprotein activity in human and rodent blood–brain barrier assessed by mechanistic modelling." Archives of Toxicology 95, no. 9 (July 15, 2021): 3015–29. http://dx.doi.org/10.1007/s00204-021-03115-y.
Nguyen, Dung N., Xiusheng Miao, Mindy Magee, Guoying Tai, Peter D. Gorycki, and Katy P. Moore. "1315. No Dose Adjustment of Metformin with Fostemsavir Coadministration Based on Mechanistic Static and Physiologically Based Pharmacokinetic Models." Open Forum Infectious Diseases 7, Supplement_1 (October 1, 2020): S669. http://dx.doi.org/10.1093/ofid/ofaa439.1497.
Liu, Jian, Swan Lin, Anthony Huynh, and Weiwei Tan. "Effects of H2-Receptor Antagonists on the Exposure of Dacomitinib." Pharmaceutics 16, no. 1 (January 17, 2024): 118. http://dx.doi.org/10.3390/pharmaceutics16010118.
Desai, Amit, Laura Kovanda, Christopher Lademacher, William Hope, Michael Neely, Peter Bonate, and Andrea Edginton. "1396. Predictions of Isavuconazonium Sulfate Dosage in Patients Aged 6 Months: <18 Years by Physiologically Based Pharmacokinetic Modeling." Open Forum Infectious Diseases 5, suppl_1 (November 2018): S429—S430. http://dx.doi.org/10.1093/ofid/ofy210.1227.
Zhou, Kaixiang, Meixia Huo, Wenjin Ma, Kun Mi, Xiangyue Xu, Samah Attia Algharib, Shuyu Xie, and Lingli Huang. "Application of a Physiologically Based Pharmacokinetic Model to Develop a Veterinary Amorphous Enrofloxacin Solid Dispersion." Pharmaceutics 13, no. 5 (April 22, 2021): 602. http://dx.doi.org/10.3390/pharmaceutics13050602.
Mian, P., K. Allegaert, S. Conings, P. Annaert, D. Tibboel, M. Pfister, K. van Calsteren, JN van den Anker, and A. Dallmann. "P66 Characterization of the pharmacokinetics of acetaminophen and its metabolites in the fetus through integration of placental transfer in a physiologically based pharmacokinetic model." Archives of Disease in Childhood 104, no. 6 (May 17, 2019): e44.2-e45. http://dx.doi.org/10.1136/archdischild-2019-esdppp.104.
Li, Yuezhe, A. Katharina Wilkins, Tim Knab, and Joseph P. Boni. "Abstract 875: Quantitative systems pharmacology modeling of loncastuximab tesirine combined with mosunetuzumab and glofitamab helps guide dosing for patients with DLBCL." Cancer Research 84, no. 6_Supplement (March 22, 2024): 875. http://dx.doi.org/10.1158/1538-7445.am2024-875.
Türk, Denise, Nina Hanke, and Thorsten Lehr. "A Physiologically-Based Pharmacokinetic Model of Trimethoprim for MATE1, OCT1, OCT2, and CYP2C8 Drug–Drug–Gene Interaction Predictions." Pharmaceutics 12, no. 11 (November 10, 2020): 1074. http://dx.doi.org/10.3390/pharmaceutics12111074.
Marok, Fatima Zahra, Jan-Georg Wojtyniak, Laura Maria Fuhr, Dominik Selzer, Matthias Schwab, Johanna Weiss, Walter Emil Haefeli, and Thorsten Lehr. "A Physiologically Based Pharmacokinetic Model of Ketoconazole and Its Metabolites as Drug–Drug Interaction Perpetrators." Pharmaceutics 15, no. 2 (February 17, 2023): 679. http://dx.doi.org/10.3390/pharmaceutics15020679.
Pepin, Xavier J. H., Natalie J. Sanderson, Alexander Blanazs, Shveta Grover, Timothy G. Ingallinera, and James C. Mann. "Bridging in vitro dissolution and in vivo exposure for acalabrutinib. Part I. Mechanistic modelling of drug product dissolution to derive a P-PSD for PBPK model input." European Journal of Pharmaceutics and Biopharmaceutics 142 (September 2019): 421–34. http://dx.doi.org/10.1016/j.ejpb.2019.07.014.
Fenneteau, F., J. Li, L. Couture, J. Turgeon, and F. Nekka. "Prediction of the disposition of a P-gp substrate in wild-type and knockout mice tissues: Development of a physiologically based pharmacokinetic (PBPK) model and its global sensitivity analysis." PAMM 7, no. 1 (December 2007): 1121905–6. http://dx.doi.org/10.1002/pamm.200700608.
Xie, Yuewu, Huixiang Liu, Xiaoyue Chen, and Jie Xing. "The Effect of Gastric pH on the Pharmacokinetics-pharmacodynamics of Naphthoquine in Rodents, as well as in Human Predicted Using a PBPK Model." Current Drug Metabolism 22, no. 5 (July 15, 2021): 363–71. http://dx.doi.org/10.2174/1389200222666210129102411.
del Río, A., C. García-de-la-Mària, J. M. Entenza, O. Gasch, Y. Armero, D. Soy, C. A. Mestres, et al. "Fosfomycin plus β-Lactams as Synergistic Bactericidal Combinations for Experimental Endocarditis Due to Methicillin-Resistant and Glycopeptide-Intermediate Staphylococcus aureus." Antimicrobial Agents and Chemotherapy 60, no. 1 (November 2, 2015): 478–86. http://dx.doi.org/10.1128/aac.02139-15.
Dennison, James E., Philip L. Bigelow, and Melvin E. Andersen. "Occupational exposure limits in the context of solvent mixtures, consumption of ethanol, and target tissue dose." Toxicology and Industrial Health 20, no. 6-10 (July 2004): 165–75. http://dx.doi.org/10.1191/0748233704th203oa.
Hu, Jing, Zhengbao Zhang, Senwei Lin, Qiuhuan Zhang, Guoxia Du, Ruishan Zhou, Xiaohan Qu, Guojiang Xu, Ying Yang, and Yongming Cai. "Application of All-Ages Lead Model Based on Monte Carlo Simulation of Preschool Children’s Exposure to Lead in Guangdong Province, China." Sustainability 15, no. 2 (January 6, 2023): 1068. http://dx.doi.org/10.3390/su15021068.
Ibrahim, A. H., H. Barry, and C. M. Hughes. "A cross-sectional survey of general practitioners’ experiences with, views of, and attitudes towards, practice-based pharmacists." International Journal of Pharmacy Practice 29, Supplement_1 (March 26, 2021): i24—i25. http://dx.doi.org/10.1093/ijpp/riab015.029.
Jayawardena, Thilina U., Lei Wang, K. K. Asanka Sanjeewa, Sang In Kang, Jung-Suck Lee, and You-Jin Jeon. "Antioxidant Potential of Sulfated Polysaccharides from Padina boryana; Protective Effect against Oxidative Stress in In Vitro and In Vivo Zebrafish Model." Marine Drugs 18, no. 4 (April 14, 2020): 212. http://dx.doi.org/10.3390/md18040212.
Audi, Said H., Anthony Cammarata, Anne V. Clough, Ranjan K. Dash, and Elizabeth R. Jacobs. "Quantification of mitochondrial membrane potential in the isolated rat lung using rhodamine 6G." Journal of Applied Physiology 128, no. 4 (April 1, 2020): 892–906. http://dx.doi.org/10.1152/japplphysiol.00789.2019.
Tudora, Anabella, and Franz-Josef Hambsch. "Parameterisation of the residual temperature distribution based on the modelling of successive emission of prompt neutrons." EPJ Web of Conferences 169 (2018): 00025. http://dx.doi.org/10.1051/epjconf/201816900025.
Shea, T. C., J. R. Mason, A. M. Storniolo, B. Newton, M. Breslin, M. Mullen, D. M. Ward, L. Miller, M. Christian, and R. Taetle. "Sequential cycles of high-dose carboplatin administered with recombinant human granulocyte-macrophage colony-stimulating factor and repeated infusions of autologous peripheral-blood progenitor cells: a novel and effective method for delivering multiple courses of dose-intensive therapy." Journal of Clinical Oncology 10, no. 3 (March 1992): 464–73. http://dx.doi.org/10.1200/jco.1992.10.3.464.
Kallidaikurichi Srinivasan, Karthikeyan, Anthony Gallagher, Niall O’Brien, Vinod Sudir, Nick Barrett, Raymund O’Connor, Francesca Holt, Peter Lee, Brian O’Donnell, and George Shorten. "Proficiency-based progression training: an ‘end to end’ model for decreasing error applied to achievement of effective epidural analgesia during labour: a randomised control study." BMJ Open 8, no. 10 (October 2018): e020099. http://dx.doi.org/10.1136/bmjopen-2017-020099.
Hanke, Nina, Sebastian Frechen, Daniel Moj, Hannah Britz, Thomas Eissing, Thomas Wendl, and Thorsten Lehr. "PBPK Models for CYP3A4 and P-gp DDI Prediction: A Modeling Network of Rifampicin, Itraconazole, Clarithromycin, Midazolam, Alfentanil, and Digoxin." CPT: Pharmacometrics & Systems Pharmacology 7, no. 10 (September 7, 2018): 647–59. http://dx.doi.org/10.1002/psp4.12343.
Zubair, Abba, Rhonda Grant, Han Tun, Candido Rivera, Alvaro Moreno-aspitia, Vivek Roy, Gerry Colon-Otero, and Lawrence Solberg. "Platelet Count Is a Sensitive Predictor of Bone Marrow Reserve and Autologous Peripheral Blood Progenitor Cell Mobilization." Blood 106, no. 11 (November 16, 2005): 5280. http://dx.doi.org/10.1182/blood.v106.11.5280.5280.
Liu, Xingbang, and Yong He. "Effect and Clinical Value of Protective Motivation Intervention Rehabilitation Model on Pain Perception and Dysfunction in Patients with Lumbar Disc Herniation: Based on a Retrospective Cohort Study." Computational and Mathematical Methods in Medicine 2022 (August 30, 2022): 1–8. http://dx.doi.org/10.1155/2022/5911889.
Weaver, CH, B. Hazelton, R. Birch, P. Palmer, C. Allen, L. Schwartzberg, and W. West. "An analysis of engraftment kinetics as a function of the CD34 content of peripheral blood progenitor cell collections in 692 patients after the administration of myeloablative chemotherapy." Blood 86, no. 10 (November 15, 1995): 3961–69. http://dx.doi.org/10.1182/blood.v86.10.3961.bloodjournal86103961.
Glass, Bertram, Lutz Uharek, Matthias Zeis, Peter Dreger, Helmut Löffler, Jörg Steinmann, and Norbert Schmitz. "Allogeneic Peripheral Blood Progenitor Cell Transplantation in a Murine Model: Evidence for an Improved Graft-Versus-Leukemia Effect." Blood 90, no. 4 (August 15, 1997): 1694–700. http://dx.doi.org/10.1182/blood.v90.4.1694.
Glass, Bertram, Lutz Uharek, Matthias Zeis, Peter Dreger, Helmut Löffler, Jörg Steinmann, and Norbert Schmitz. "Allogeneic Peripheral Blood Progenitor Cell Transplantation in a Murine Model: Evidence for an Improved Graft-Versus-Leukemia Effect." Blood 90, no. 4 (August 15, 1997): 1694–700. http://dx.doi.org/10.1182/blood.v90.4.1694.1694_1694_1700.
Schiedlmeier, B., K. Kühlcke, H. G. Eckert, C. Baum, W. J. Zeller, and S. Fruehauf. "Quantitative assessment of retroviral transfer of the human multidrug resistance 1 gene to human mobilized peripheral blood progenitor cells engrafted in nonobese diabetic/severe combined immunodeficient mice." Blood 95, no. 4 (February 15, 2000): 1237–48. http://dx.doi.org/10.1182/blood.v95.4.1237.
Gubanova, M. V., N. N. Kushnarenko, and T. M. Karavaeva. "Clinical significance of 24-hour blood pressure monitoring in prediction of hypertension development in patients with gout." Siberian Journal of Clinical and Experimental Medicine 36, no. 3 (October 7, 2021): 104–10. http://dx.doi.org/10.29001/2073-8552-2021-36-3-104-110.
Seeger, Timon, Marlon Veldwijk, Gary Bridger, Gary Calandra, Hartmut Goldschmidt, Anthony Ho, and Stefan Fruehauf. "The CXCR4 Antagonist AMD3100 Mobilizes a More Primitive Subset of CD34+ Cells Than G-CSF." Blood 106, no. 11 (November 16, 2005): 1969. http://dx.doi.org/10.1182/blood.v106.11.1969.1969.
Goldberg, Joel, Christopher Bethel, Andrea M. Hujer, Steven Marshall, Magdalena A. Taracila, Krisztina M. Papp-Wallce, Vijay Kumar, Focco van den Akker, Mark Plummer, and Robert A. Bonomo. "1256. In Vivo Activity and Structural Characterization of a New Generation γ-Lactam Siderophore Antibiotic Against Multidrug-Resistant Gram-Negative Bacteria and Acinetobacter spp." Open Forum Infectious Diseases 7, Supplement_1 (October 1, 2020): S645. http://dx.doi.org/10.1093/ofid/ofaa439.1440.
Wilmsmeier, Lisa, Jeannine Von Der Born, Rizky I. Sugianto, Carl Grabitz, Bernhard Mw Schmidt, Ana Celine Braun, Denise Homeyer, Uwe Tegtbur, and Anette Melk. "SIGNIFICANT INCREASES IN PERIPHERAL AND CENTRAL BLOOD PRESSURE IN CHILDREN AT MUCH LOWER BODY MASS INDEX THAN EXPECTED." Journal of Hypertension 42, Suppl 1 (May 2024): e11. http://dx.doi.org/10.1097/01.hjh.0001019420.16281.8a.