Journal articles on the topic 'P-glycoprotein inhibitors'
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Gherbovet, Olga, María Concepción García Alvarez, Jérôme Bignon, and Fanny Roussi. "Original Vinca Derivatives: From P-Glycoprotein Substrates to P-Glycoprotein Inhibitors." Journal of Medicinal Chemistry 59, no. 23 (November 23, 2016): 10774–80. http://dx.doi.org/10.1021/acs.jmedchem.6b00525.
Full textChae, Song Wha, Jaeok Lee, Jung Hyun Park, Youngjoo Kwon, Younghwa Na, and Hwa Jeong Lee. "Intestinal P-glycoprotein inhibitors, benzoxanthone analogues." Journal of Pharmacy and Pharmacology 70, no. 2 (December 13, 2017): 234–41. http://dx.doi.org/10.1111/jphp.12832.
Full textal-Shawi, M. K., I. L. Urbatsch, and A. E. Senior. "Covalent inhibitors of P-glycoprotein ATPase activity." Journal of Biological Chemistry 269, no. 12 (March 1994): 8986–92. http://dx.doi.org/10.1016/s0021-9258(17)37065-5.
Full textKono, Yusuke, Iichiro Kawahara, Kohei Shinozaki, Ikuo Nomura, Honoka Marutani, Akira Yamamoto, and Takuya Fujita. "Characterization of P-Glycoprotein Inhibitors for Evaluating the Effect of P-Glycoprotein on the Intestinal Absorption of Drugs." Pharmaceutics 13, no. 3 (March 15, 2021): 388. http://dx.doi.org/10.3390/pharmaceutics13030388.
Full textPleban, Karin, and Gerhard Ecker. "Inhibitors of P-Glycoprotein - Lead Identification and Optimisation." Mini-Reviews in Medicinal Chemistry 5, no. 2 (February 1, 2005): 153–63. http://dx.doi.org/10.2174/1389557053402729.
Full textYu, Jun, Peng Zhou, James Asenso, Xiao-Dan Yang, Chun Wang, and Wei Wei. "Advances in plant-based inhibitors of P-glycoprotein." Journal of Enzyme Inhibition and Medicinal Chemistry 31, no. 6 (March 2, 2016): 867–81. http://dx.doi.org/10.3109/14756366.2016.1149476.
Full textSrivalli, Kale Mohana Raghava, and P. K. Lakshmi. "Overview of P-glycoprotein inhibitors: a rational outlook." Brazilian Journal of Pharmaceutical Sciences 48, no. 3 (September 2012): 353–67. http://dx.doi.org/10.1590/s1984-82502012000300002.
Full textChang, Cheng, Praveen M. Bahadduri, James E. Polli, Peter W. Swaan, and Sean Ekins. "Rapid Identification of P-glycoprotein Substrates and Inhibitors." Drug Metabolism and Disposition 34, no. 12 (September 22, 2006): 1976–84. http://dx.doi.org/10.1124/dmd.106.012351.
Full textBogman, Katrijn, Anne-Kathrin Peyer, Michael Török, Ernst Küsters, and Jürgen Drewe. "HMG-CoA reductase inhibitors and P-glycoprotein modulation." British Journal of Pharmacology 132, no. 6 (March 2001): 1183–92. http://dx.doi.org/10.1038/sj.bjp.0703920.
Full textTarasova, Nadya I., Rishi Seth, Sergey G. Tarasov, Teresa Kosakowska-Cholody, Christine A. Hrycyna, Michael M. Gottesman, and Christopher J. Michejda. "Transmembrane Inhibitors of P-Glycoprotein, an ABC Transporter." Journal of Medicinal Chemistry 48, no. 11 (June 2005): 3768–75. http://dx.doi.org/10.1021/jm049065t.
Full textLi-Blatter, Xiaochun, Pierluigi Nervi, and Anna Seelig. "Detergents as intrinsic P-glycoprotein substrates and inhibitors." Biochimica et Biophysica Acta (BBA) - Biomembranes 1788, no. 10 (October 2009): 2335–44. http://dx.doi.org/10.1016/j.bbamem.2009.07.010.
Full textKim, Richard B. "Drugs as P-glycoprotein substrates, inhibitors, and inducers." Drug Metabolism Reviews 34, no. 1-2 (January 2002): 47–54. http://dx.doi.org/10.1081/dmr-120001389.
Full textRehman, Saleha, Bushra Nabi, Mohammad Fazil, Saba Khan, Naimat Kalim Bari, Romi Singh, Shavej Ahmad, Varinder Kumar, Sanjula Baboota, and Javed Ali. "Role of P-Glycoprotein Inhibitors in the Bioavailability Enhancement of Solid Dispersion of Darunavir." BioMed Research International 2017 (2017): 1–17. http://dx.doi.org/10.1155/2017/8274927.
Full textDastvan, Reza, Smriti Mishra, Yelena B. Peskova, Robert K. Nakamoto, and Hassane S. Mchaourab. "Mechanism of allosteric modulation of P-glycoprotein by transport substrates and inhibitors." Science 364, no. 6441 (May 16, 2019): 689–92. http://dx.doi.org/10.1126/science.aav9406.
Full textGrigoreva, T., A. Romanova, A. Sagaidak, S. Vorona, D. Novikova, and V. Tribulovich. "Mdm2 inhibitors as a platform for the design of P-glycoprotein inhibitors." Bioorganic & Medicinal Chemistry Letters 30, no. 18 (September 2020): 127424. http://dx.doi.org/10.1016/j.bmcl.2020.127424.
Full textDemeule, Michel, Alain Laplante, Arash Sepehr-Araé, Édith Beaulieu, Diana Averill-Bates, Roland M. Wenger, and Richard Béliveau. "Inhibition of P-glycoprotein by cyclosporin A analogues and metabolites." Biochemistry and Cell Biology 77, no. 1 (March 1, 1999): 47–58. http://dx.doi.org/10.1139/o99-011.
Full textPrié, Dominique, Sylviane Couette, Isabelle Fernandes, Caroline Silve, and Gérard Friedlander. "P-glycoprotein inhibitors stimulate renal phosphate reabsorption in rats." Kidney International 60, no. 3 (September 2001): 1069–76. http://dx.doi.org/10.1046/j.1523-1755.2001.0600031069.x.
Full textBisi, Alessandra, Silvia Gobbi, Angela Rampa, Federica Belluti, Lorna Piazzi, Piero Valenti, Nora Gyemant, and Joseph Molnár. "New Potent P-Glycoprotein Inhibitors Carrying a Polycyclic Scaffold." Journal of Medicinal Chemistry 49, no. 11 (June 2006): 3049–51. http://dx.doi.org/10.1021/jm060056p.
Full textZaja, Roko, Senka Terzić, Ivan Senta, Jovica Lončar, Marta Popović, Marijan Ahel, and Tvrtko Smital. "Identification of P-Glycoprotein Inhibitors in Contaminated Freshwater Sediments." Environmental Science & Technology 47, no. 9 (April 18, 2013): 4813–21. http://dx.doi.org/10.1021/es400334t.
Full textAlcantara, Laura M., Junwon Kim, Carolina B. Moraes, Caio H. Franco, Kathrin D. Franzoi, Sukjun Lee, Lucio H. Freitas-Junior, and Lawrence S. Ayong. "Chemosensitization potential of P-glycoprotein inhibitors in malaria parasites." Experimental Parasitology 134, no. 2 (June 2013): 235–43. http://dx.doi.org/10.1016/j.exppara.2013.03.022.
Full textYasuda, Kazuto, Lu-bin Lan, Dominique Sanglard, Katryn Furuya, John D. Schuetz, and Erin G. Schuetz. "Interaction of Cytochrome P450 3A Inhibitors with P-Glycoprotein." Journal of Pharmacology and Experimental Therapeutics 303, no. 1 (October 1, 2002): 323–32. http://dx.doi.org/10.1124/jpet.102.037549.
Full textXia, Mengmeng, Yajing Fang, Weiwei Cao, Fuqiang Liang, Siyi Pan, and Xiaoyun Xu. "Quantitative Structure–Activity Relationships for the Flavonoid-Mediated Inhibition of P-Glycoprotein in KB/MDR1 Cells." Molecules 24, no. 9 (April 27, 2019): 1661. http://dx.doi.org/10.3390/molecules24091661.
Full textKopecka, Joanna, Martina Godel, Silvia Dei, Roberta Giampietro, Dimas Carolina Belisario, Muhlis Akman, Marialessandra Contino, Elisabetta Teodori, and Chiara Riganti. "Insights into P-Glycoprotein Inhibitors: New Inducers of Immunogenic Cell Death." Cells 9, no. 4 (April 22, 2020): 1033. http://dx.doi.org/10.3390/cells9041033.
Full textMiyata, Yukio, Yasushi Asano, and Shigeaki Muto. "Effects of P-glycoprotein on cell volume regulation in mouse proximal tubule." American Journal of Physiology-Renal Physiology 280, no. 5 (May 1, 2001): F829—F837. http://dx.doi.org/10.1152/ajprenal.2001.280.5.f829.
Full textWang, Pei-Hua, Yi-Shu Tu, and Yufeng J. Tseng. "PgpRules: a decision tree based prediction server for P-glycoprotein substrates and inhibitors." Bioinformatics 35, no. 20 (March 27, 2019): 4193–95. http://dx.doi.org/10.1093/bioinformatics/btz213.
Full textArora, Neha. "Structural Mapping of Inhibitors Binding Sites on P-glycoprotein: Mechanism of Inhibition of P-Glycoprotein by Herbal Isoflavones." International Journal of Biochemistry Research & Review 3, no. 4 (January 10, 2013): 421–35. http://dx.doi.org/10.9734/ijbcrr/2013/3268.
Full textKurnik, Daniel, Gbenga G. Sofowora, John P. Donahue, Usha B. Nair, Grant R. Wilkinson, Alastair J. J. Wood, and Mordechai Muszkat. "Tariquidar, a Selective P-glycoprotein Inhibitor, Does Not Potentiate Loperamide’s Opioid Brain Effects in Humans despite Full Inhibition of Lymphocyte P-glycoprotein." Anesthesiology 109, no. 6 (December 1, 2008): 1092–99. http://dx.doi.org/10.1097/aln.0b013e31818d8f28.
Full textWestwell, Andrew D. "Novel telomerase inhibitors targeting quadreplex DNA; antitumour benzothiazoles; P-Glycoprotein efflux pump inhibitors; new topoisomerase inhibitors." Drug Discovery Today 7, no. 9 (May 2002): 528–31. http://dx.doi.org/10.1016/s1359-6446(02)02247-x.
Full textLiu, Hongming, Zhiguo Ma, and Baojian Wu. "Structure-activity relationships andin silicomodels of P-glycoprotein (ABCB1) inhibitors." Xenobiotica 43, no. 11 (April 25, 2013): 1018–26. http://dx.doi.org/10.3109/00498254.2013.791003.
Full textBansal, Tripta, Manu Jaggi, Roop Khar, and Sushama Talegaonkar. "Status of Flavonols as P-Glycoprotein Inhibitors in Cancer Chemotherapy." Current Cancer Therapy Reviews 5, no. 2 (May 1, 2009): 89–99. http://dx.doi.org/10.2174/157339409788166742.
Full textWang, R. B., C. L. Kuo, L. L. Lien, and E. J. Lien. "Structure-activity relationship: analyses of p-glycoprotein substrates and inhibitors." Journal of Clinical Pharmacy and Therapeutics 28, no. 3 (June 2003): 203–28. http://dx.doi.org/10.1046/j.1365-2710.2003.00487.x.
Full textLeopoldo, Marcello, Patrizia Nardulli, Marialessandra Contino, Francesco Leonetti, Gert Luurtsema, and Nicola Antonio Colabufo. "An updated patent review on P-glycoprotein inhibitors (2011-2018)." Expert Opinion on Therapeutic Patents 29, no. 6 (May 17, 2019): 455–61. http://dx.doi.org/10.1080/13543776.2019.1618273.
Full textJakubowski, Piotr, Michał Majewski, Piotr Podlasz, Anna Jakimiuk, and Natalia Kasica. "P-glycoprotein inhibitors modulate levetiracetam effects in zebrafish epilepsy model." Pharmacological Reports 67 (September 2015): 23. http://dx.doi.org/10.1016/j.pharep.2015.06.071.
Full textMollazadeh, Shirin, Amirhossein Sahebkar, Farzin Hadizadeh, Javad Behravan, and Sepideh Arabzadeh. "Structural and functional aspects of P-glycoprotein and its inhibitors." Life Sciences 214 (December 2018): 118–23. http://dx.doi.org/10.1016/j.lfs.2018.10.048.
Full textZeino, Maen, Malte S. Paulsen, Martin Zehl, Ernst Urban, Brigitte Kopp, and Thomas Efferth. "Identification of new P-glycoprotein inhibitors derived from cardiotonic steroids." Biochemical Pharmacology 93, no. 1 (January 2015): 11–24. http://dx.doi.org/10.1016/j.bcp.2014.10.009.
Full textCrivori, Patrizia, Benedetta Reinach, Daniele Pezzetta, and Italo Poggesi. "Computational Models for Identifying Potential P-Glycoprotein Substrates and Inhibitors." Molecular Pharmaceutics 3, no. 1 (December 8, 2005): 33–44. http://dx.doi.org/10.1021/mp050071a.
Full textPan, Xianchao, Li Chao, Wen Tan, Li Yang, Roman Podraza, and Hu Mei. "Emerging chemical patterns applied to prediction of P-glycoprotein inhibitors." Chemometrics and Intelligent Laboratory Systems 137 (October 2014): 140–45. http://dx.doi.org/10.1016/j.chemolab.2014.06.017.
Full textPan, Qiangrong, Qinghua Lu, Kun Zhang, and Xun Hu. "Dibenzocyclooctadiene lingnans: a class of novel inhibitors of P-glycoprotein." Cancer Chemotherapy and Pharmacology 58, no. 1 (October 18, 2005): 99–106. http://dx.doi.org/10.1007/s00280-005-0133-1.
Full textDong, Jinyun, Zuodong Qin, Wei-Dong Zhang, Gang Cheng, Assaraf G. Yehuda, Charles R. Ashby, Zhe-Sheng Chen, Xiang-Dong Cheng, and Jiang-Jiang Qin. "Medicinal chemistry strategies to discover P-glycoprotein inhibitors: An update." Drug Resistance Updates 49 (March 2020): 100681. http://dx.doi.org/10.1016/j.drup.2020.100681.
Full textWang, Zhen, Iris L. K. Wong, Fu Xing Li, Chao Yang, Zhen Liu, Tao Jiang, Ting Fu Jiang, Larry M. C. Chow, and Sheng Biao Wan. "Optimization of permethyl ningalin B analogs as P-glycoprotein inhibitors." Bioorganic & Medicinal Chemistry 23, no. 17 (September 2015): 5566–73. http://dx.doi.org/10.1016/j.bmc.2015.07.027.
Full textChen, Lei, Youyong Li, Huidong Yu, Liling Zhang, and Tingjun Hou. "Computational models for predicting substrates or inhibitors of P-glycoprotein." Drug Discovery Today 17, no. 7-8 (April 2012): 343–51. http://dx.doi.org/10.1016/j.drudis.2011.11.003.
Full textKadioglu, Onat, and Thomas Efferth. "A Machine Learning-Based Prediction Platform for P-Glycoprotein Modulators and Its Validation by Molecular Docking." Cells 8, no. 10 (October 21, 2019): 1286. http://dx.doi.org/10.3390/cells8101286.
Full textSugie, Masami, Emiko Asakura, Ying Lan Zhao, Shoko Torita, Masayuki Nadai, Kenji Baba, Kiyoyuki Kitaichi, Kenji Takagi, Kenzo Takagi, and Takaaki Hasegawa. "Possible Involvement of the Drug Transporters P Glycoprotein and Multidrug Resistance-Associated Protein Mrp2 in Disposition of Azithromycin." Antimicrobial Agents and Chemotherapy 48, no. 3 (March 2004): 809–14. http://dx.doi.org/10.1128/aac.48.3.809-814.2004.
Full textSergent, Jacques-Aurélien, Hilarion Mathouet, Christian Hulen, Pedro Lameiras, Marc Feuilloley, Abdelhakim Elomri, and Nour-Eddine Lomri. "Effects of Two Natural Bisbenzylisoquinolines, Curine and Guattegaumerine, Extracted from Isolona hexaloba on Rhodamine Efflux by Abcb1b from Rat Glycocholic-Acid-Resistant Hepatocarcinoma Cells." Molecules 27, no. 9 (May 9, 2022): 3030. http://dx.doi.org/10.3390/molecules27093030.
Full textXing, Juan, Shuheng Huang, Yu Heng, Hu Mei, and Xianchao Pan. "Computational Insights into Allosteric Conformational Modulation of P-Glycoprotein by Substrate and Inhibitor Binding." Molecules 25, no. 24 (December 18, 2020): 6006. http://dx.doi.org/10.3390/molecules25246006.
Full textKatayama, Kazuhiro, Kohji Noguchi, and Yoshikazu Sugimoto. "Regulations of P-Glycoprotein/ABCB1/MDR1 in Human Cancer Cells." New Journal of Science 2014 (May 20, 2014): 1–10. http://dx.doi.org/10.1155/2014/476974.
Full textMiller, David S., Caroline R. Sussman, and J. Larry Renfro. "Protein kinase C regulation of p-glycoprotein-mediated xenobiotic secretion in renal proximal tubule." American Journal of Physiology-Renal Physiology 275, no. 5 (November 1, 1998): F785—F795. http://dx.doi.org/10.1152/ajprenal.1998.275.5.f785.
Full textRAGGERS, René J., Ilse VOGELS, and Gerrit van MEER. "Multidrug-resistance P-glycoprotein (MDR1) secretes platelet-activating factor." Biochemical Journal 357, no. 3 (July 25, 2001): 859–65. http://dx.doi.org/10.1042/bj3570859.
Full textMarques, Sérgio M., Lucie Šupolíková, Lenka Molčanová, Karel Šmejkal, David Bednar, and Iva Slaninová. "Screening of Natural Compounds as P-Glycoprotein Inhibitors against Multidrug Resistance." Biomedicines 9, no. 4 (March 30, 2021): 357. http://dx.doi.org/10.3390/biomedicines9040357.
Full textMora Lagares, Liadys, Nikola Minovski, and Marjana Novič. "Multiclass Classifier for P-Glycoprotein Substrates, Inhibitors, and Non-Active Compounds." Molecules 24, no. 10 (May 25, 2019): 2006. http://dx.doi.org/10.3390/molecules24102006.
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