Journal articles on the topic 'Ozone Health aspects'

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1

Barczyk, Izabela, Diana Masłyk, Natalia Walczuk, Karina Kijak, Piotr Skomro, Helena Gronwald, Maria Pawlak, et al. "Potential Clinical Applications of Ozone Therapy in Dental Specialties—A Literature Review, Supported by Own Observations." International Journal of Environmental Research and Public Health 20, no. 3 (January 22, 2023): 2048. http://dx.doi.org/10.3390/ijerph20032048.

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Apart from conventional treatment, dentists are increasingly relying on physical therapy modalities in their clinical practice. The aim of this literature review is to analyze the clinical relevance and potential uses of ozone in modern dentistry. The research question is geared towards detailing the multiple potential applications of ozone therapy in a range of dental specialties. Based on the available literature, accessed via the PubMed, Google Scholar, Scopus, and EBSCO databases, a detailed search of the electronic literature was performed for 2001–2022. Eligible studies were chosen according to inclusion and exclusion criteria, using keywords: ozone, ozone therapy, therapeutic applications, oxidants, dental disinfectants, oral medicine, physical therapy in dentistry. Out of 834 manuscripts, 273 studies were curated. A total of 70 publications were used in the final consideration. After assessing their quality, they were analyzed to determine the relevance and potential use of ozone in the various aspects of modern dentistry. Ozone therapy is used mainly as an adjunct to the primary clinical or pharmacological treatment. In some cases of oral mucosal disease, it has proven effective as a primary therapy. During the literature analysis, it was noted that ozone therapy in dentistry is a subject of ongoing research, and the results are not always consistent. The multitude of studies in the literature on the applications of ozone in dentistry reflects the search for its undiscovered physical therapeutic potential.
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Zhukova, Evgeniya S., Anna Yu Kashina, and Anastasiya M. Irkaeva. "Modern aspects of professional cancer treatment: prospects for the use of medical ozone in the correction of free radical homeostasis." Russian Journal of Occupational Health and Industrial Ecology 60, no. 11 (December 3, 2020): 767–70. http://dx.doi.org/10.31089/1026-9428-2020-60-11-767-770.

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Introduction. The well-known features of oncogenesis make it possible to assume the prospects of medical ozone as part of a comprehensive health-saving therapy for professional oncopathologies. Due to the risk of stimulating the proliferation of tumor cells, research on the search for optimal modes of ozone exposure is relevant. The aim of the study was to evaluate the possibility of using ozonated saline solution (OSS) as part of complex antitumor therapy in an experiment. Materials and methods. The effect of OSS with different concentrations of ozone in the ozone-oxygen mixture on the content of hemoglobin, active products of thiobarbituric acid (TBA) of lipid peroxidation (LP), the degree of oxidative modification of proteins, and the activity of superoxide dismutase and catalase in blood, liver, spleen, and tumor tissues was studied in Mature rats with normal and transplanted cholangiocellular carcinoma. Results. The course effect of the OSS did not have statistically significant changes in the studied biochemical parameters under the conditions of the physiological norm in the experiment. Exposure to OSS during oncogenesis led to a decrease in the content of TBA-active LP products in the liver by more than 30%. Conclusions. Course exposure to OSS with an ozone concentration in an ozone-oxygen mixture of 400 micrograms/l may be promising for the correction of free radical homeostasis as part of complex antitumor therapy, including in oncogenesis due to occupational factors.
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Hou, Yongjiang, and Zheng Shen. "Research Trends, Hotspots and Frontiers of Ozone Pollution from 1996 to 2021: A Review Based on a Bibliometric Visualization Analysis." Sustainability 14, no. 17 (August 31, 2022): 10898. http://dx.doi.org/10.3390/su141710898.

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A total of 2932 publications in the field of ozone pollution were obtained from the Web of Science and briefly reviewed using a bibliometric analysis and WOS-based citation reports. CiteSpace 5.7.R3 (64 bit) was used to perform a visualization of knowledge mapping by keywords co-words, burst analysis, co-cited reference analysis, and cooperation network analysis. Research topics in this field have mainly focused on three aspects: risk assessment of ozone pollution for both humans and plants under short-term and long-term exposure; ozone pollution characterization and modeling of ozone transport on different scales; and elucidating the mechanism of ozone formation and source apportionment. By clustering the co-cited references using the data from 2016 to 2021, the frontiers are found to be: (1) VOCs’ precursors and ozone transformation mechanism; (2) modeling of source apportionment and source-oriented chemical transport considering meteorological influence to predict ozone concentration at different spatial and temporal scales; and (3) premature mortality and health burden with relation to ozone exposure. It should be mentioned that an emerging research hotspot is the utilization of artificial intelligence (AI) tools (e.g., machine learning, deep learning, etc.) to facilitate the modeling of big data at different scales.
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Mohd Supian, Nur Amira, Nor Nadiah Abdul Karim Shah, Rosnah Shamsudin, and Alifdalino Sulaiman. "Effects of aqueous ozone treatment on the nutritional attributes of mango (Mangifera indica L.) fruit juice." International Food Research Journal 29, no. 5 (October 25, 2022): 1005–19. http://dx.doi.org/10.47836/ifrj.29.5.04.

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The global fruit juice market is expanding alongside the exponentially growing demand for a healthy lifestyle. Fruit juice is a preferred drink among all age groups as it contains numerous essential nutrients that benefit human health. The safety aspects of fruit juice are equally important as its healthy features. The conventional method of thermal pasteurisation has been known to produce fruit juice of inferior quality. Hence, ozone is being considered as an alternative, non-thermal form of pasteurisation. With its strong oxidation potential, ozone exhibits antimicrobial characteristics and produces no toxic by-products. However, for ozone to be successfully adopted by juice producers, the synergistic effects of the composition of fruit juice and ozone treatment must be adequately evaluated. Therefore, the present work subjected various concentrations of Chokanan mango juice (MJ), diluted with distilled water (DW) at 100MJ:0DW, 75MJ:25DW, and 50MJ:50DW to aqueous ozone treatment at different ozone doses. The effects of these treatments on the physicochemical and antioxidant properties of the MJ were evaluated. Ozone was found to be effective in decreasing the pectin methylesterase (PME) activity arising from the de-esterification of the pectin molecules, and increasing the DPPH activity, thereby increasing the juice quality. Significant effects on the total colour difference (ΔE) and total phenolic content (TPC) were observed in proportion to the increases in ozone dose. The colour of the treated MJ was found to be positively correlated with the TPC, while a kinetic study was performed to investigate the proportionality of the colour and TPC degradation. The first-order reaction model fitted well with the degradation patterns of L* and b*, as well as the ΔE of the MJ samples. A significant difference was observed between the degradation rate constant (k-value) for the MJ samples, which suggested that the k-value could have been affected by not only the ozone dose, but also the juice matrix. The present work demonstrated that the composition of fruit juice was an essential intrinsic parameter that must be assessed before adopting ozone as a form of non-thermal pasteurisation to produce fruit juice which is stable in quality, and safe for consumption.
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5

Kirigia, Joses. "Health impacts of epidemiological environment change: measurement issues." Environment and Development Economics 1, no. 3 (July 1996): 359–67. http://dx.doi.org/10.1017/s1355770x00000693.

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Epidemiological environment (EE) could be denned as a set of conditions and processes, both physical and social, that influence the interaction between human beings and disease agents. The human epidemiological environment is shaped by various aspects of development and global change, viz. the influences of human population size, mobility, geographic distribution, urbanization, and nutrition status; modernization (macro-and microeconomic enterprise); loss of indigenous medicinal knowledge; microbial evolution of antibiotic resistance; land conversion and biodiversity loss; agricultural intensification; stratospheric ozone depletion; and climatic change (Daily and Ehrlich, 1995). Health status is affected greatly not only by economic development (e.g. by policies influencing per capita income and its distribution), but also through changes in EE.
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6

Szyszkowicz, Mieczysław. "Concentration–Response Functions as an Essence of the Results from Lags." International Journal of Environmental Research and Public Health 19, no. 13 (July 1, 2022): 8116. http://dx.doi.org/10.3390/ijerph19138116.

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Among various aspects of environmental epidemiology, one is to assess the relationships between ambient air pollution and health outcomes. The goal of this work is to estimate the associations in the form of the parametric concentration–response functions (C-RF). Various forms of the C-RFs are proposed in this short-term health effect study. Emergency department (ED) visits for all respiratory health problems are analyzed as an illustrative example. A case-crossover (CC) technique is applied as a study design. Daily cases are organized as daily counts by the same day of the week in one common month. A conditional Poisson regression is used in the constructed statistical models. Temperature and relative humidity are included in the statistical models in the form of natural splines. Ground-level ozone concentration is considered an exposure. Ozone concentration values are transformed and submitted to the statistical models. The parameters of the transformation are determined by using the goodness of fit criterion. Counts of ED visits are analyzed in relation to a sequence of lagged exposure to ozone. The C-RF shapes are constructed for each individual lag. In a final step, the set of the estimated C-RF shapes is used to create a pooled C-RF shape. The results are positive and statistically significant for nine lagged exposures, from 0 to 8 days. The following relative risks (RR) were estimated from the constructed C-RFs at 30 ppb concentration of ozone: RR = 1.0531 (95% confidence interval: 1.0231, 1.0718), 1.0462 (1.0253, 1.0677), and 1.0387, (1.0240, 1.0531), realizing the CC method, CC method + transformation, and CC method + flexible transformation, respectively. The pooled C-RF shape gives a summary of the associations between ED visits for respiratory conditions and ambient ozone. The estimated shapes indicate lower air health effects than the standard CC methods. Among three considered statistical models, the CC method + flexible transformation is the most appropriate to use according to the goodness of fit criterion.
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7

Meghisan, Georgeta-Madalina, and Dorin Toma. "Public health management: life expectancy and air pollution." Proceedings of the International Conference on Business Excellence 11, no. 1 (July 1, 2017): 111–20. http://dx.doi.org/10.1515/picbe-2017-0012.

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Abstract Part of the National Strategy of Sustainable Development from Romania, life expectancy and air pollution indicators have an important role in establishing long term public health management strategies. International scientific literature within the field underlines the strong connection between air pollution and life expectancy. This research study focuses on the impact of greenhouse gas emissions, particulate matter air pollutants, ozone air pollutants on the length of life at 65 years old and life expectancy at birth of the population from Romania. The methods used for research are correlation and linear regression. Our results will be a starting point for further development of public health policies in developing countries, which mostly focus on socio-economic aspects, neglecting the negative impact of air pollution.
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Dragone, Roberto, Giorgio Licciardi, Gerardo Grasso, Costantino Del Gaudio, and Jocelyn Chanussot. "Analysis of the Chemical and Physical Environmental Aspects that Promoted the Spread of SARS-CoV-2 in the Lombard Area." International Journal of Environmental Research and Public Health 18, no. 3 (January 29, 2021): 1226. http://dx.doi.org/10.3390/ijerph18031226.

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Recent works have demonstrated that particulate matter (PM) and specific meteorological conditions played an important role in the airborne transmission of the SARS-CoV-1 and MERS-CoV. These studies suggest that these parameters could influence the transmission of SARS-CoV-2. In the present investigation, we sought to investigate the association between air pollution, meteorological data, and the Lombardy region COVID-19 outbreak caused by SARS-CoV-2. We considered the number of detected infected people at the regional and provincial scale from February to March 2020. Air pollution data were collected over the Lombardy region, nominally, sulphur dioxide, ammonia, nitrogen dioxide, nitrogen monoxide, carbon monoxide, ozone, and suspended particulate matter measuring less than 10 μm (PM10) and less than 2.5 μm (PM2.5). Meteorological data have been collected over the same region for temperature, relative humidity, and wind speed. In this work, we evaluated the combined impact of environmental pollutants and climate conditions on the COVID-19 outbreak. The analysis evidenced a positive correlation between spatial distribution of COVID-19 infection cases with high concentrations of suspended particulate matter and a negative relationship with ozone. Moreover, suspended particulate matter concentration peaks in February correlated positively with infection peaks according to the virus incubation period. The obtained results suggested that seasonal weather conditions and concentration of air pollutants seemed to influence COVID-19 epidemics in Lombardy region.
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9

CHATTERJEE, KALIPADA. "Atmospheric ozone monitoring in the Indian network in view of possibility of damage to the biosphere due to distortion of ozone layer." MAUSAM 37, no. 4 (April 7, 2022): 471–82. http://dx.doi.org/10.54302/mausam.v37i4.2568.

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Atmospheric ozone protects life on the earth from harmful ultraviolet radiation of wavelengths in the biologically important 300nanometre region. In recent year many workers in the field of atmospheric ozone have brought out the various effects of oxides of nitrogen (NOx) Oxides of chlorine (CIOx) and Hydroxyl radicals (HOx) on the ozone layer due to man made activities. It has been demonstrated by recent studies that monsoon season these man made chemicals like NOx, ClOx released in the troposphere due to industrializations may eventually deplete ozone in the stratosphere by as much as 5% at the present rate of discharge of these chemicals in the lower troposphere. This depletion of total ozone could cause an increase in the incident of skin cancer. Furthermore these are indications of the possibility that plant life and marine life and other ecological systems are also affected cultural planning by the changes in ultraviolet radiation. The ozone layer in the stratosphere controls the temperature & winds in the stratosphere and have a great influence in the general circulation & climate of the earth. Depletion of ozone in the stratosphere due to man made actitives, may therefore cause adverse effects on the earth’s climate. Model calculation indicate that early next Century the combined radiative effects of ozone and other trace gases would be of the same order as that calculated for CO2. Recent studies in the field of tropospheric ozone have indicated that due to man made activities possibility of sharp increase in the tropospheric ozone particularly in the industrially developed countries. This increase in the tropospheric ozone could adversely effect human health and plant life particularly forest resources. It has, therefore, become very important to accurately monitor atmospheric ozone on a routine and network basis over the entire globe by insitu, balloon borne and satellite measurements. The present paper brings out the results and analysis of total ozone, vertical ozone measurements by Umkehr and balloon sonde and tropospheric ozone measurements by ground based and balloon borne sondes made in the Indian network during the last decade (1970-1979) and various aspects of ozone profiles and variations and ozone trend analysis over the years have been presented and discussed in this paper.
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10

Catalano, Paul J., Louise M. Ryan, and Debra A. Kaden. "Statistical Design Aspects of the Ntp/Hei Collaborative Study on the Health Effects of Chronic Ozone Inhalation." Inhalation Toxicology 8, no. 3 (January 1996): 229–49. http://dx.doi.org/10.3109/08958379609005432.

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11

Taylor, Allyn L. "Governing the Globalization of Public Health." Journal of Law, Medicine & Ethics 32, no. 3 (2004): 500–508. http://dx.doi.org/10.1111/j.1748-720x.2004.tb00163.x.

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The number and the scale of transboundary public health concerns are increasing. Infectious and non-communicable diseases, international trade in tobacco, alcohol, and other dangerous products as well as the control of the safety of health services, pharmaceuticals, and food are merely a few examples of contemporary transnationalization of health concerns. The rapid development and diffusion of scientific and technological developments across national borders are creating new realms of international health concern, such as aspects of biomedical science, including human reproductive cloning, germ-line therapy, and xenotransplantation, as well as environmental health problems, including climate change, biodiversity loss, and depletion of the ozone layer. Growth in international trade and travel, in combination with population growth, has served to increase the frequency and intensity of health concerns bypassing or spilling over sovereign boundaries.Although health has traditionally been seen an area of limited multilateral cooperation, there is growing awareness that contemporary globalization has led to the proliferation of cross border determinants of health status and is undermining the capacity of nation states to protect health through domestic action alone.
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Anav, Alessandro, Alessandra De Marco, Alessio Collalti, Lisa Emberson, Zhaozhong Feng, Danica Lombardozzi, Pierre Sicard, et al. "Legislative and functional aspects of different metrics used for ozone risk assessment to forests." Environmental Pollution 295 (February 2022): 118690. http://dx.doi.org/10.1016/j.envpol.2021.118690.

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13

Khalifa, Shaden A. M., Mahmoud M. Swilam, Aida A. Abd El-Wahed, Ming Du, Haged H. R. El-Seedi, Guoyin Kai, Saad H. D. Masry, et al. "Beyond the Pandemic: COVID-19 Pandemic Changed the Face of Life." International Journal of Environmental Research and Public Health 18, no. 11 (May 25, 2021): 5645. http://dx.doi.org/10.3390/ijerph18115645.

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The COVID-19 pandemic is a serious challenge for societies around the globe as entire populations have fallen victim to the infectious spread and have taken up social distancing. In many countries, people have had to self-isolate and to be confined to their homes for several weeks to months to prevent the spread of the virus. Social distancing measures have had both negative and positive impacts on various aspects of economies, lifestyles, education, transportation, food supply, health, social life, and mental wellbeing. On other hands, due to reduced population movements and the decline in human activities, gas emissions decreased and the ozone layer improved; this had a positive impact on Earth’s weather and environment. Overall, the COVID-19 pandemic has negative effects on human activities and positive impacts on nature. This study discusses the impact of the COVID-19 pandemic on different life aspects including the economy, social life, health, education, and the environment.
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Cherevaschenko, Lyubov A., L. YU Dadova, Nikolay N. Kulikov, Anatolii T. Tereshin, and Igor A. Cherevashchenko. "The experience of using iodine-bromine baths and ozone therapy at the stage of health resort treatment of patients with chronic cerebral ischemia." Russian Journal of Physiotherapy, Balneology and Rehabilitation 17, no. 5 (July 30, 2020): 263–71. http://dx.doi.org/10.17816/1681-3456-2018-17-5-263-271.

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Background. Treatment of chronic cerebral ischemia should be aimed both to the main etiological factor and to the pathogenetic mechanisms of cerebral ischemia and hypoxia. The action of ozone therapy is characterized with a multilateral positive effect on the main aspects of chronic cerebral ischemia pathogenesis, such as chronic cerebral hypoxia, impaired microcirculation, rheological disorders, and activation of lipid peroxidation. The use of iodine-bromine baths in chronic cerebral ischemia has been proved to be accompanied by an improvement in cerebral circulation, normalization of the brain bioelectric processes, an initially impaired condition of the autonomic nervous system, and an increase in the level of adaptive capabilities of the body. Aim: to develop effective pathogenetically substantiated methods for the combined use of iodine-bromine baths and ozone therapy in patients with chronic cerebral ischemia to increase the effectiveness of health resort treatment. Methods. In accordance with the tasks set in the work, 90 patients with chronic cerebral ischemia of the degree 1, who were randomized into three treatment groups, were examined and treated. Patients of the control group (n = 30) received iodine-bromine baths, patients of the comparison group (n = 30) received ozone therapy, patients of the main group (n = 30) received iodine-bromine baths and ozone therapy. Examination of patients included Doppler ultrasound, electroencephalography, rheoencephalography, сardiointervalography, lipid metabolism studies, fibrinogen content studies. Results. As a result of treatment, the improvement of clinical symptoms and the normalization of biochemical and neurophysiological parameters were noted in patients of all treatment groups. Overall efficiency (improvement and significant improvement) was 53.3% in the control group, in the comparison group it was 63.3%, and 73.3% in the main group. Conclusion. The authors proved the practicability of rehabilitative treatment of early forms of vascular diseases of the brain at the stage of sanatorium and resort rehabilitation, which is due to significant compensatory reserves and high plasticity of the structural and functional formations of the brain with preserved ability to develop nonspecific elements of the nervous tissue and restore reversibly damaged structures.
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Szyszkowicz, Mieczyslaw, and Nicholas de Angelis. "Urban Air Pollution and Emergency Department Visits for Cardiac and Respiratory Diseases." Advances in Environmental and Engineering Research 3, no. 1 (September 18, 2021): 1. http://dx.doi.org/10.21926/aeer.2201005.

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Air pollution affects various aspects of human health. Here, the associations between the number of emergency department visits for circulatory and respiratory problems and ambient air pollution in Toronto, Canada, in the period between April 2004 and December 2015 were studied. The health data were linked with urban air pollution data and weather factors. The conditional Poisson regression models were built for 18 strata (sex, age group, season), 8 exposure factors (air pollutants, indexes), and their 15 lags (0-14 days). Circulatory problems: the associations were intensified in the cold period (October - March) and were associated with the air quality health index (AQHI). The estimated relative risks for all patients in the cold period, for an increase of the AQHI by 1, at lags 0, 1, and 2 were 1.017 and 95% confidence interval (1.010, 1.024), 1.014 (1.007, 1.021), and 1.009 (1.002, 1.016). Respiratory problems: the analogous results for ozone and its increase by 12.8 ppb at lags 3, 4, and 5 were 1.052 (1.033, 1.161), 1.039 (1.020, 1.121), and 1.027 (1.008, 1.082). It was observed that exposure to certain air pollutants (nitrogen dioxide, ozone, and the AQHI index) are associated with increased emergency department visits in both cardiac and respiratory health problems.
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Daily, Gretchen C., and Paul R. Ehrlich. "Impacts of development and global change on the epidemiological environment." Environment and Development Economics 1, no. 3 (July 1996): 311–46. http://dx.doi.org/10.1017/s1355770x00000656.

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AbstractAlthough improvements in human health represent a crucial aspect of development worldwide, many trends associated with development and global change appear to be reducing health security. In this article, we define the human epidemiological environment and describe key biophysical, economic, sociocultural, and political factors that shape it. The potential impact upon the epidemiological environment of aspects of both development and global change are then examined: the influences of human population size, mobility, geographic distribution, and nutritional status; modernization; loss of indigenous medicinal knowledge; microbial evolution of antibiotic resistance; land conversion and biodiversity loss; agricultural intensification; stratospheric ozone depletion; and climate change. Human vulnerability to infectious disease is often strongly and deleteriously influenced by ongoing, intensifying changes in these factors. An unprecedented level of communication and cooperation between experts, institutions, and nations is required to respond to the increasing threat of epidemic disease, which points to a promising area for enhanced interdisciplinary collaboration.
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Jimenez-Montenegro, Lucia, Matilde Lopez-Fernandez, and Estela Gimenez. "Worldwide Research on the Ozone Influence in Plants." Agronomy 11, no. 8 (July 28, 2021): 1504. http://dx.doi.org/10.3390/agronomy11081504.

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Tropospheric ozone (O3) is a secondary air pollutant and a greenhouse gas, whose concentration has been increasing since the industrial era and is expected to increase further in the near future. O3 molecules can be inhaled by humans and animals, causing significant health problems; they can also diffuse through the leaf stomata of plants, triggering significant phytotoxic damage that entails a weakening of the plant, reducing its ability to cope with other abiotic and biotic stresses. This eventually leads to a reduction in the yield and quality of crops, which is a serious problem as it puts global food security at risk. Due to the importance of this issue, a bibliometric analysis on O3 in the plant research field is carried out through the Web of Science (WoS) database. Different aspects of the publications are analysed, such as the number of documents published per year, the corresponding scientific areas, distribution of documents by countries, institutions and languages, publication type and affiliations, and, finally, special attention is paid to O3 study in plants by means of studies about the word occurrence frequency in titles and abstracts, and the articles most frequently cited. The bibliometric study shows the great effort made by the scientific community in order to understand the damages caused by O3 in plants, which will help reduce the big losses that O3 causes in agriculture.
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Baia, Gabriela M., Otniel Freitas-Silva, and Murillo F. Junior. "Understanding the Role of Chlorine and Ozone to Control Postharvest Diseases in Fruit and Vegetables: A Review." Current Nutrition & Food Science 16, no. 4 (July 13, 2020): 455–61. http://dx.doi.org/10.2174/1573401315666190212161209.

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Fruits and vegetables are foods that come into contact with various types of microorganisms from planting to their consumption. A lack or poor sanitation of these products after harvest can cause high losses due to deterioration and/ or pathogenic microorganisms. There are practically no post-harvest fungicides or bactericides with a broad spectrum of action that have no toxic residual effects and are safe. However, to minimize such problems, the use of sanitizers is an efficient device against these microorganisms. Chlorine is the most prevalent sanitizing agent because of its broad spectrum, low cost and well-established practices. However, the inevitable formation of disinfection by-products, such as trihalomethanes (THMs) and haloacetic acids (HAAs), is considered one of the main threats to food safety. Alternative sanitizers, such as chlorine dioxide (ClO2) and ozone, are becoming popular as a substitute for traditional post-harvest treatments. Thus, this review addresses the use of chlorine, chlorine dioxide and ozone emphasizing aspects, such as usage, safe application, spectrum of action and legislation. In order to ensure the quality and safety of final products, the adoption of well-prepared sanitation and sanitation programs for post-harvest fruits and vegetables is essential.
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Mishra, Punit, Shubham Soni, and Govind Maheshwari. "Thermodynamic Analysis of Split Air Conditioner Using Energy and Exergy Viewpoint with Low GWP Refrigerants Alternative to R410A." E3S Web of Conferences 309 (2021): 01141. http://dx.doi.org/10.1051/e3sconf/202130901141.

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In this paper, a comparative thermodynamic analysis on energy and exergy viewpoint is done on different low global warming potential (GWP) refrigerants to find the possible alternative of high GWP refrigerant R410A. R410A is used nowadays in air conditioning systems due to its ozone-friendly characteristic as zero ozone depletion potential (ODP=0) but it has high GWP (GWP=1924) that leads to global warming. Now a day’s global warming is considered to be one of the critical aspects when environmental protection is taken into consideration and researchers from every corner of the globe are working to find refrigerants that not only have zero ODP but it has low GWP too. In this analysis, four prospect refrigerants namely R32, R447A, R447B, and R452B have been studied to find their suitability to replace R410A on different performance criteria as the coefficient of performance (COP), power consumption, exergy efficiency, and exergy destruction. Thermodynamic properties of the studied refrigerants have been taken from the Genetron Properties 1.4 software. The result indicates that all the studied refrigerants have better performance characteristics compared to R410A but R447A has maximum COP and exergy efficiency along with the least total exergy destruction that makes it a possible alternate of R410A.
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Andersson, Camilla, Heléne Alpfjord, Lennart Robertson, Per Erik Karlsson, and Magnuz Engardt. "Reanalysis of and attribution to near-surface ozone concentrations in Sweden during 1990–2013." Atmospheric Chemistry and Physics 17, no. 22 (November 22, 2017): 13869–90. http://dx.doi.org/10.5194/acp-17-13869-2017.

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Abstract. We have constructed two data sets of hourly resolution reanalyzed near-surface ozone (O3) concentrations for the period 1990–2013 for Sweden. Long-term simulations from a chemistry-transport model (CTM) covering Europe were combined with hourly ozone concentration observations at Swedish and Norwegian background measurement sites using retrospective variational data analysis. The reanalysis data sets show improved performance over the original CTM when compared to independent observations. In one of the reanalyses, we included all available hourly near-surface O3 observations, whilst in the other we carefully selected time-consistent observations. Based on the second reanalysis we investigated statistical aspects of the distribution of the near-surface O3 concentrations, focusing on the linear trend over the 24-year period. We show that high near-surface O3 concentrations are decreasing and low O3 concentrations are increasing, which is reflected in observed improvement of many health and vegetation indices (apart from those with a low threshold). Using the CTM we also conducted sensitivity simulations to quantify the causes of the observed change, focusing on three factors: change in hemispheric background concentrations, meteorology and anthropogenic emissions. The rising low concentrations of near-surface O3 in Sweden are caused by a combination of all three factors, whilst the decrease in the highest O3 concentrations is caused by European O3 precursor emissions reductions. While studying the impact of anthropogenic emissions changes, we identified systematic differences in the modeled trend compared to observations that must be caused by incorrect trends in the utilized emissions inventory or by too high sensitivity of our model to emissions changes.
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Bui, Alex A. T., Anahita Hosseini, Rose Rocchio, Nate Jacobs, Mindy K. Ross, Sande Okelo, Fred Lurmann, et al. "Biomedical REAl-Time Health Evaluation (BREATHE): toward an mHealth informatics platform." JAMIA Open 3, no. 2 (May 7, 2020): 190–200. http://dx.doi.org/10.1093/jamiaopen/ooaa011.

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Abstract Objective To describe a configurable mobile health (mHealth) framework for integration of physiologic and environmental sensors to be used in studies focusing on the domain of pediatric asthma. Materials and Methods The Biomedical REAl-Time Health Evaluation (BREATHE) platform connects different sensors and data streams, contextualizing an individual’s symptoms and daily activities over time to understand pediatric asthma’s presentation and its management. A smartwatch/smartphone combination serves as a hub for personal/wearable sensing devices collecting data on health (eg, heart rate, spirometry, medications), motion, and personal exposures (eg, particulate matter, ozone); securely transmitting information to BREATHE’s servers; and interacting with the user (eg, ecological momentary assessments). Server-side integration of electronic health record data and spatiotemporally correlated information (eg, weather, traffic) elaborates on these observations. An initial panel study involving pediatric asthma patients was conducted to assess BREATHE. Results Twenty subjects were enrolled, during which BREATHE accrued seven consecutive days of continuous data per individual. The data were used to confirm knowledge about asthma (use of controller inhalers, time-activity behaviors, personal air pollution exposure), and additional analyses provided insights into within-day associations of environmental triggers and asthma exacerbations. Exit surveys focusing on mHealth usability, while positive, noted several translational challenges. Discussion Based on these promising results, a longitudinal panel study to evaluate individual microenvironments and exposures is ongoing. Lessons learned thus far reflect the need to address various usability aspects, including convenience and ongoing engagement. Conclusion BREATHE enables multi-sensor mHealth studies, capturing new types of information alongside an evolving understanding of personal exposomes.
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Makenga Bof, Jean-Claude, Paul Mansiangi, Horlyne Nsangi, Éric Mafuta, Isabelle Aujoulat, and Yves Coppieters. "Community Participation in and Perception of Community-Directed Treatment with Ivermectin in Kinshasa, DRC." Tropical Medicine and Infectious Disease 4, no. 3 (July 19, 2019): 109. http://dx.doi.org/10.3390/tropicalmed4030109.

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The success of community-directed treatment with Ivermectin (CDTI) depends on active community participation. We conducted a case study nested in a cross-sectional study in the Binza Ozone Health Zone (ZS) in Kinshasa, Democratic Republic of Congo, in order to investigate community’s knowledges and perceptions of onchocerciasis and on all CDTI’s aspects. We interviewed 106 people aged 20 and over, purposively selected, through eight individual interviews and 12 focus groups. Themes used for collecting data were drawn for the Health Belief Model and data were analyzed using a deductive thematic approach. The term onchocerciasis was unknown to participants who called it “Mbitiri”, the little black fly, in their local language. This disease is seen as curse put on the sufferer by a witch and perceived as a threat because of the “Mbitiri” bites. The afflicted participants were reluctant to seek treatment and preferred traditional practitioners or healers. CDTI is considered devastating because of adverse effects of ivermectin as well as inefficient after occurrence of deaths. This explains the low level of community adhesion and participation to this strategy. Recruitment procedures for community distributors are poorly understood and awareness and health education campaigns are either non-existent or rarely carried out. Nevertheless, the latter should be regularly done.
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Bonn, Boris, Erika von Schneidemesser, Dorota Andrich, Jörn Quedenau, Holger Gerwig, Anja Lüdecke, Jürgen Kura, et al. "BAERLIN2014 – the influence of land surface types on and the horizontal heterogeneity of air pollutant levels in Berlin." Atmospheric Chemistry and Physics 16, no. 12 (June 24, 2016): 7785–811. http://dx.doi.org/10.5194/acp-16-7785-2016.

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Abstract. Urban air quality and human health are among the key aspects of future urban planning. In order to address pollutants such as ozone and particulate matter, efforts need to be made to quantify and reduce their concentrations. One important aspect in understanding urban air quality is the influence of urban vegetation which may act as both emitter and sink for trace gases and aerosol particles. In this context, the "Berlin Air quality and Ecosystem Research: Local and long-range Impact of anthropogenic and Natural hydrocarbons 2014" (BAERLIN2014) campaign was conducted between 2 June and 29 August in the metropolitan area of Berlin and Brandenburg, Germany. The predominant goals of the campaign were (1) the characterization of urban gaseous and particulate pollution and its attribution to anthropogenic and natural sources in the region of interest, especially considering the connection between biogenic volatile organic compounds and particulates and ozone; (2) the quantification of the impact of urban vegetation on organic trace gas levels and the presence of oxidants such as ozone; and (3) to explain the local heterogeneity of pollutants by defining the distribution of sources and sinks relevant for the interpretation of model simulations. In order to do so, the campaign included stationary measurements at urban background station and mobile observations carried out from bicycle, van and airborne platforms. This paper provides an overview of the mobile measurements (Mobile BAERLIN2014) and general conclusions drawn from the analysis. Bicycle measurements showed micro-scale variations of temperature and particulate matter, displaying a substantial reduction of mean temperatures and particulate levels in the proximity of vegetated areas compared to typical urban residential area (background) measurements. Van measurements extended the area covered by bicycle observations and included continuous measurements of O3, NOx, CO, CO2 and point-wise measurement of volatile organic compounds (VOCs) at representative sites for traffic- and vegetation-affected sites. The quantification displayed notable horizontal heterogeneity of the short-lived gases and particle number concentrations. For example, baseline concentrations of the traffic-related chemical species CO and NO varied on average by up to ±22.2 and ±63.5 %, respectively, on the scale of 100 m around any measurement location. Airborne observations revealed the dominant source of elevated urban particulate number and mass concentrations being local, i.e., not being caused by long-range transport. Surface-based observations related these two parameters predominantly to traffic sources. Vegetated areas lowered the pollutant concentrations substantially with ozone being reduced most by coniferous forests, which is most likely caused by their reactive biogenic VOC emissions. With respect to the overall potential to reduce air pollutant levels, forests were found to result in the largest decrease, followed by parks and facilities for sports and leisure. Surface temperature was generally 0.6–2.1 °C lower in vegetated regions, which in turn will have an impact on tropospheric chemical processes. Based on our findings, effective future mitigation activities to provide a more sustainable and healthier urban environment should focus predominantly on reducing fossil-fuel emissions from traffic as well as on increasing vegetated areas.
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Ohipeni, Edwin Angmor Kofi. "5G Cellular Network Forensics." Advances in Multidisciplinary and scientific Research Journal Publication 1, no. 1 (July 26, 2022): 181–84. http://dx.doi.org/10.22624/aims/crp-bk3-p29.

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The fifth generation (5G) of cellular networks will bring 10Gbps user speeds, have a wider bandwidth which can accommodate 1000 times what the fourth generation (4G) could and 100 times faster than the previous 4G cellular network. This paper’s focus is to highlight on the legal aspects of the 5G cellular network. That is, the health issues, privacy, and security issues on Africans. Most crimes currently are facilitated by cellular network devices and with the improvement that the 5G cellular network brings, there is going to be an increase in cybercrime and hence the need for forensics. These forensics’ techniques used in evidence acquisition violates the privacy and security of the users of the 5G cellular network. Keywords: Cellular Networks, Fifth Generation (5G), Lawful Interception (LI), Lawful Access Location Services (LALS), Privacy, Security, Africa, Natural Resources, Carbon, Ozone Layer, Internet of Things (IoT) BOOK Chapter ǀ Research Nexus in IT, Law, Cyber Security & Forensics. Open Access. Distributed Free Citation: Edwin Angmor Kofi Ohipeni (2022): 5G Cellular Network Forensics Book Chapter Series on Research Nexus in IT, Law, Cyber Security & Forensics. Pp 181-184 www.isteams.net/ITlawbookchapter2022. dx.doi.org/10.22624/AIMS/CRP-BK3-P29
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Glevitzky, Ioana, Adina Sârb, and Maria Popa. "Study Regarding the Improvement of Bottling Process for Spring Waters, through the Implementation of the Occupational Health and Food Safety Requirements." Safety 5, no. 2 (May 22, 2019): 32. http://dx.doi.org/10.3390/safety5020032.

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The design, development and deployment, alongside with preventive maintenance of equipment helps with controlling safety issues in water bottling processes. However, these aspects are not-enough to prevent accidents; they must be closely related to the implementation of quality, occupational health and safety, and food security standards. The approach presented in this paper was to show a summary of the assessment of the risks of injury and professional illness for all within the organization according to the ISO 45001:2018 standard. Also, a statistical analysis was performed to evaluate the occurrence of defects in different equipment in the technological process. The paper highlights the safety parameters of the spring water “Roua Apusenilor” namely the: organoleptic, physic-chemical and microbiological ones, according to the European legislation. A hazard analysis and critical control points (HACCP) generic model was developed for this process. In this case study, the analysis and assessment of hazards that may occur during processing was implemented for still water bottling stages, as was an identification of the critical control points, which include filtration and ozone water treatment. The HACCP principles, included in the ISO 22000:2018 standard, were applied in order to improve the food safety and security, to reduce the risks resulting from the consumption of “Roua Apusenilor” spring water and, also, for increasing customer confidence. The obtained results significantly relied upon the situation found in the industrial company used as a benchmark for the research. The analysis revealed that, considered safety standards OHSAS (ISO 45001) and HACCP (ISO 22000) share the same goal of safety production for safe food products.
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Amaral, Karina Guedes Cubas do, Julio Cezar Rietow, and Miguel Mansur Aisse. "Evaluation of the environmental life cycle of an STP that employs a low-rate trickling filter as post-treatment of a UASB reactor and different sludge-management alternatives." Ambiente e Agua - An Interdisciplinary Journal of Applied Science 16, no. 3 (May 20, 2021): 1. http://dx.doi.org/10.4136/ambi-agua.2648.

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This study aimed to undertake an environmental life cycle assessment (LCA) of a sewage treatment plant (STP) equipped with low-rate trickling filters (TFs) as post-treatment of upflow anaerobic sludge blanket (UASB). The STP is located in South Brazil and uses landfill and agriculture as sludge-disposal alternatives. The evaluation was performed using the LCA technique and SimaPro® 9 software. The results revealed that the gases methane (CH4) and sulfur dioxide (SO2), emitted into the atmosphere after the partial burning of the biogas in flares, are mainly responsible for impacts in the categories of global warming (GW) and terrestrial acidification (TA), respectively. Due to the low rate of hydraulic sewage application in TFs, nitrous oxide (N2O) emissions stood out due to their high impact in the category of stratospheric ozone depletion (SOD). The use of sludge in agriculture obtained a greater potential for environmental impact compared to landfills in five of the eight categories evaluated. The main impacts of agricultural use were in the category of human toxicity (HT), due to the high concentration of zinc present in the sludge, and in the category TA, due to the emission of ammonia (NH3) during hygienization of the sludge. In turn, the main positive aspects were avoided products, such as urea, phosphate fertilizer and limestone. The results contribute to a greater discussion of sewage-treatment processes, as well as sludge-management alternatives used in developing countries.
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Sreesurya, Aitha. "IOT based Voice Controlled Robot with Pollution Detection." International Journal for Research in Applied Science and Engineering Technology 9, no. VI (June 10, 2021): 118–23. http://dx.doi.org/10.22214/ijraset.2021.34883.

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Air pollution is a serious situation which ruins future generations.as of increasing population daily, lots of exploitation of resources takes place which in turn causes pollution. Mainly pollution due to vehicles & industries leads to much damage of health hazards and turned out to be one of the major problem world is facing now. Apart from oxygen, we breathe in fumes. outdoor air pollution has existed for a long time. Radon, volatile organic compounds, formaldehyde, biological contaminants, and combustion by-products such as carbon monoxide, carbon dioxide, sulfur dioxide, hydrocarbons, nitrogen dioxides, and particles contribute to indoor air pollution, sulfur dioxide, carbon monoxide, nitrogen oxides, ozone, total suspended particle matter, lead, carbon dioxide, and hazardous pollutants are the principal pollutants that contribute to outdoor air pollution. Air pollution causes severe diseases like asthma, cancer, breathing, skin irritation, and liver problems. We see there’s a lot of pollution around us makes it difficult for plants, animals, and humans to survive as the air becomes polluted. the pollution due to vehicles is one of the major aspects of pollution. this is because of in efficient fuel in vehicles and long term of vehicles (internal problem). so we have come up with a solution by testing this application by making voice controlled robot with pollution detection at toll gates.
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Mansouri, Aya, Wenjuan Wei, Jean-Marie Alessandrini, Corinne Mandin, and Patrice Blondeau. "Impact of Climate Change on Indoor Air Quality: A Review." International Journal of Environmental Research and Public Health 19, no. 23 (November 24, 2022): 15616. http://dx.doi.org/10.3390/ijerph192315616.

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Climate change can affect the indoor environment due to heat and mass transfers between indoor and outdoor environments. To mitigate climate change impacts and adapt buildings to the changing environment, changes in building characteristics and occupants’ behavior may occur. To characterize the effects of climate change on indoor air quality (IAQ), the present review focused on four aspects: (1) experimental and modeling studies that relate IAQ to future environmental conditions, (2) evolution of indoor and outdoor air concentrations in the coming years with regard to temperature rise, (3) climate change mitigation and adaptation actions in the building sector, and (4) evolution of human behavior in the context of climate change. In the indoor environment, experimental and modeling studies on indoor air pollutants highlighted a combined effect of temperature and relative humidity on pollutant emissions from indoor sources. Five IAQ models developed for future climate data were identified in the literature. In the outdoor environment, the increasing ambient temperature may lead directly or indirectly to changes in ozone, particle, nitrogen oxides, and volatile organic compound concentrations in some regions of the world depending on the assumptions made about temperature evolution, anthropogenic emissions, and regional regulation. Infiltration into buildings of outdoor air pollutants is governed by many factors, including temperature difference between indoors and outdoors, and might increase in the years to come during summer and decrease during other seasons. On the other hand, building codes in some countries require a higher airtightness for new and retrofitted buildings. The building adaptation actions include the reinforcement of insulation, implementation of new materials and smart building technologies, and a more systematic and possibly longer use of air conditioning systems in summer compared to nowadays. Moreover, warmer winters, springs, and autumns may induce an increasing duration of open windows in these seasons, while the use of air conditioning in summer may reduce the duration of open windows.
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Zębek, Elżbieta. "Important issues in select European Union countries’ criminal environmental law in compliance with Directive 2008/99/EC." Vestnik of Saint Petersburg University. Law 12, no. 2 (2021): 356–73. http://dx.doi.org/10.21638/spbu14.2021.207.

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This article analyzes issues in criminal environmental law in Poland, the Czech Republic and Germany, which implemented the provisions of the European Commission Directive 2008/99/EC. The provisions of this directive changed the scope of protection of environmental resources in these countries’ penal codes to varying extents. These three countries have been relatively successful in comprehensively implementing criminal directive provisions. This included changes in the special protection of Natura 2000 sites and ozone depleting substances. Legal systems are generally based on prevention and risk assessment, and the basic conditions of criminal responsibility for environmental crimes include “significant damage, causing damage to the health of another or animals and plants, damage to other property and also water, air, soil and environmental components which have significant value”. Additional aspects include environmental damage over larger areas and restoration costs. However, the greatest current problem is the vague definition of conditions of criminal responsibility, which makes it difficult to enforce legislation. The following postulates de lege ferenda were formulated: clarify the premises for offenses against the environment, specify the costs of remedying environmental damage, define critical emission standards for environmental crime, as well as specify activities in protected areas that threaten objects. This article emphasizes that an increased and better definition of the conditions of criminal responsibility for environmental crimes enacted by EU countries may contribute to more effective enforcement of infringements of environmental protection law.
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Truffo, Davide, Josè Miguel Peña Suarèz, Juan Bandera Cantalejo, Marìa Del Carmen Gonzalez Muriano, Francisco Garcias Vacas, and Francisco Fernandez Hernàndez. "Comparative study of purifications technologies and their application to HVAC systems." E3S Web of Conferences 343 (2022): 03005. http://dx.doi.org/10.1051/e3sconf/202234303005.

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Nowadays, there is a growing demand to guarantee indoor air quality in buildings. This study presents a solution that combines hygrothermal control and purification of the air supplied to occupied spaces, in which the control and purification system is integrated into the air distribution ductwork. Among all the air purification technologies, not all of them are suitable to be used in the residential and tertiary sector along with already installed HVAC systems. In this study, a review of the state of the art of technologies is made and the major purification techniques are analysed and compared, i.e., negative ionization, ozone, ultraviolet light, photocatalytic oxidation, and high-efficiency filtration. The comparison is focused on key aspects such as the use with occupation, whether there is a biocide or not, whether it can be used with HVAC units, costs, and maintenance. Finally, an effective and viable purification solution for HVAC systems is presented. It consists of a compact device based on the ionization technology. An ionizer device is placed in the air in-take of ducted HVAC units that is capable of remotely controlling the main operating parameters of the HVAC equipment (switching on and off, operating mode, fan speed, and setpoint temperature) while reducing the suspension time of fine particles in the air. Various studies carried out in Airzone laboratories have empirically shown that the use of this device results in a 47% reduction in the maximum concentration of particulate matter of 2.5 µm or PM2.5 and up to a 55% reduction of the time these particles are suspended in the air.
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Pham Thi, Ben, Van Pham Thi, and Phuong Bui Thi Anh. "Impacts of air pollution on children with disabilities: A narrative review." Journal of Science Educational Science 66, no. 4AB (October 2021): 145–59. http://dx.doi.org/10.18173/2354-1075.2021-0069.

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Air pollution is one of the global problems with adverse effects on many aspects of human life, on different population groups and on the ecology of animals and plants. The effects of air pollution on disadvantaged communities in society such as children with disabilities are also considered. This paper describes the research results on the effects of air pollution on children with disabilities through narrative review and content analysis from 39 articles published from 2010 to 2020. Results showed that most studies were conducted in developed countries from the large survey sample sizes in wide age ranges from from pregnancy to 19 years of age in longitudinal, cross-sectional and retrospective study designs. Air pollution is determined based on the indicators of nitrogen dioxide (NO2), black carbon (BC), fine particulate matter (PM) such as PM1, PM2.5, PM10, sulfur dioxide (SO2), polycyclic aromatic hydrocarbon (PAH), benzene, ground-level ozone and solid biomass smoke. Results from the review showcased that air pollution has an effect on a high risk of autism spectrum disorders, attention deficit hyperactivity disorder, intellectual disability, behavioral and emotional disorders including depression and psychosis. In addition, studies have also shown that air pollution has serious effects on children's brain development and physical health such as impaired fetal neural development, premature brain imbalance, inflammation, and changes in fetal brain structure. Showing the relationship between air pollution and children's disability may indicate that environmental pollution is considered as a factor that negatively affects the disability etiology and severity. Showing this relationship contributes to promoting environmental protection, reducing pollution including air pollution at national and global scale.
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Feng, Chen. "Granger Causality Analysis of Foreign Trade in Cement Products and Ecological Impact in China." Mathematical Problems in Engineering 2022 (July 8, 2022): 1–11. http://dx.doi.org/10.1155/2022/3467483.

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This paper presents an in-depth study and analysis of the impact of foreign trade on cement products and the ecological environment in China through Granger causality analysis. Based on the theoretical basis of foreign trade, ecological environment, and the relationship between them, a general equilibrium model is used to empirically analyze the “three effects” of foreign trade in Chinese cement products on the ecological environment, and the effects of import and export trade on ecological environment and the net effects are calculated, respectively. Then, based on the data of domestic and foreign cement product production and trade, the purpose, scope, and environmental impact factors of the ecological impact of foreign trade of Chinese cement products were determined by the life cycle assessment method, and the inventory analysis was carried out in phases based on the six aspects of nonrenewable resource depletion, global warming, photochemical ozone generation, acidification, eutrophication, and human health damage. The results were characterized and standardized, and the hierarchical analysis method was used to weight the evaluation of each environmental impact type, and finally, the resource consumption coefficient and environmental impact load index values and corresponding ratios were determined based on the green product evaluation method. This paper establishes an index system for the ecological and environmental impacts of foreign trade of cement products, which is a guide for the ecological and environmental impacts of foreign trade of other products in China. The results of the study on the ecological and environmental impacts of foreign trade of Chinese cement products also have important practical significance for the formulation of regulations and standards related to the cement industry, the adjustment of the import and export structure of cement products, and the improvement of production equipment and processes.
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de Vries, Wim, Hans Kros, Oene Oenema, and Jan Willem Erisman. "Assessment of Nitrogen Ceilings for Dutch Agricultural Soils to Avoid Adverse Environmental Impacts." Scientific World JOURNAL 1 (2001): 898–907. http://dx.doi.org/10.1100/tsw.2001.333.

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In the Netherlands, high traffic density and intensive animal husbandry have led to high emissions of reactive nitrogen (N) into the environment. This leads to a series of environmental impacts, including: (1) nitrate (NO3) contamination of drinking water, (2) eutrophication of freshwater lakes, (3) acidification and biodiversity impacts on terrestrial ecosystems, (4) ozone and particle formation affecting human health, and (5) global climate change induced by emissions of N2O. Measures to control reactive N emissions were, up to now, directed towards those different environmental themes. Here we summarize the results of a study to analyse the agricultural N problem in the Netherlands in an integrated way, which means that all relevant aspects are taken into account simultaneously. A simple N balance model was developed, representing all crucial processes in the N chain, to calculate acceptable N inputs to the farm (so-called N ceiling) and to the soil surface (application in the field) by feed concentrates, organic manure, fertiliser, deposition, and N fixation. The N ceilings were calculated on the basis of critical limits for NO3concentrations in groundwater, N concentrations in surface water, and ammonia (NH3) emission targets related to the protection of biodiversity of natural areas. Results show that in most parts of the Netherlands, except the western and the northern part, the N ceilings are limited by NH3emissions, which are derived from critical N loads for nature areas, rather than limits for both ground- and surface water. On the national scale, the N ceiling ranges between 372 and 858 kton year–1depending on the choice of critical limits. The current N import is 848 kton year–1. A decrease of nearly 60% is needed to reach the ceilings that are necessary to protect the environment against all adverse impacts of N pollution from agriculture.
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Vendruscolo, Cynthia do Prado, Juliana Junqueira Moreira, Sarah Raphaela Torquato Seidel, Joice Fülber, Henrique Macedo Neuenschwander, Giancarlo Bonagura, Fernanda Rodrigues Agreste, and Raquel Yvonne Arantes Baccarin. "Effects of medical ozone upon healthy equine joints: Clinical and laboratorial aspects." PLOS ONE 13, no. 5 (May 29, 2018): e0197736. http://dx.doi.org/10.1371/journal.pone.0197736.

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Jaramillo, F. M., C. P. Vendruscolo, J. Fülber, S. R. T. Seidel, A. P. Barbosa, and R. Y. A. Baccarin. "Effects of transrectal medicinal ozone in horses - clinical and laboratory aspects." Arquivo Brasileiro de Medicina Veterinária e Zootecnia 72, no. 1 (January 2020): 56–64. http://dx.doi.org/10.1590/1678-4162-11155.

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ABSTRACT Ozone (O3) therapy has been used for medical procedures for centuries; however, there are no extensive studies on its utilization in horses. This study aimed to evaluate the application of transrectal O3 on horses by physical and laboratorial evaluation, and production of reactive oxygen species (ROS). Sixteen healthy horses were separated in two groups: a control group (CG) and a group treated with O3 (TG). The TG animals received 1L of an oxygen and O3 mixture transrectally. The initial dose was 10µg/ml for the first two applications, 15μg/ml for the following two applications, and 20μg/ml for the next six applications. The CG animals received 1L of oxygen transrectally. In TG animals no variations in the physical examination were detected; furthermore, TG animals did not exhibit changes in biochemical evaluation results, fibrinogen concentrations, or ROS production. TG animals had increased red blood cell counts, hemoglobin concentrations, and packet cell volume values in comparison to the baseline and CG values. We could infer that O3 affected the red blood cell counts and improved rhetological properties of the blood. The transrectal application of O3 in horses is safe and can indirectly improve the oxygenation and metabolism of tissues.
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Moat, John, James Cargill, John Shone, and Mathew Upton. "Application of a novel decontamination process using gaseous ozone." Canadian Journal of Microbiology 55, no. 8 (August 2009): 928–33. http://dx.doi.org/10.1139/w09-046.

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Environmental disinfection in a health care setting is an important aspect of infection control. Recently, there has been interest in the use of vapor- and gas-based treatments for decontamination of surfaces and rooms. We describe preliminary results for an ozone-based decontamination of surfaces seeded with a range of vegetative cells and spores of bacteria of clinical relevance. The efficacy of the approach for room sanitization was also assessed. The protocol included use of a quenching agent to rapidly reduce ozone concentrations to safe levels allowing treatment times of less than 1 h for the majority of organisms tested. Using bacteria seeded onto agar plates and solid surfaces, reductions in bacterial load of greater than 3 log values were recorded for a number of organisms including Escherichia coli and methicillin-resistant Staphylococcus aureus . Application of the process in a 30 m3room showed similar reductions in viable counts for these organisms and for Clostridium difficile spores. We suggest that the potential of this ozone–quench approach should be further evaluated for disinfection or decontamination of healthcare environments.
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Abreu-Villela, Paula, Mario Ferraro, Renata R. Rodrigues, Daniel G. Ferro, Denise T. Fantoni, Ivan Hong Jun Koh, and Marco Antonio Gioso. "Ozone Therapy in the Prevention of Dental Plaque Formation in Dogs." Journal of Veterinary Dentistry 38, no. 1 (March 2021): 18–23. http://dx.doi.org/10.1177/08987564211013920.

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This study aims to assess ozonized mineral oil ointment application as an antiplaque therapy for dogs. Domestic healthy dogs received dental scaling and polishing under general anesthesia. Under standard feeding and homecare during 7 days, 20 dogs were randomly placed into 2 different groups for dental treatment. The control group (CG) was given a single placebo application and the ozone group (O3G) received daily ozonized ointment application. The average age (CG = 4.4; O3G = 5.7 years old), body weight (CG = 15.7; O3G = 15.3 kg) and the gingivitis index obtained on the first day (D0) allowed initial homogeneity between the groups. The dental plaque index, including clinical and computerized analysis on the seventh day, was obtained from the buccal aspect of specific dental locations. Both analyses revealed significant statistical association between daily application of ozone and antiplaque effect. There was no evidence of toxicity during the study. These results suggest that ozone therapy may be an efficient adjuvant to conventional periodontal treatment in decreasing initial dental plaque formation.
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Chang, C. Y., C. Y. Chiu, S. J. Lee, W. H. Huang, Y. H. Yu, H. T. Liou, Y. Ku, and J. N. Chen. "Mass transfer aspect of ozone absorption and decomposition in aqueous solution with ultraviolet radiation." Toxicological & Environmental Chemistry 57, no. 1-4 (December 1996): 37–52. http://dx.doi.org/10.1080/02772249609358375.

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Parodis, I., A. Gomez, A. Tsoi, J. Weng Chow, D. Pezzella, C. Girard, T. Stamm, and C. Boström. "POS1506-HPR SYSTEMATIC LITERATURE REVIEW TO INFORM THE EULAR TASK FORCE FOR RECOMMENDATIONS/POINTS TO CONSIDER FOR THE NON-PHARMACOLOGICAL MANAGEMENT OF SYSTEMIC LUPUS ERYTHEMATOSUS AND SYSTEMIC SCLEROSIS." Annals of the Rheumatic Diseases 81, Suppl 1 (May 23, 2022): 1098–99. http://dx.doi.org/10.1136/annrheumdis-2022-eular.4029.

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BackgroundThe heterogeneity and complexity of the chronic autoimmune diseases systemic lupus erythematosus (SLE) and systemic sclerosis (SSc) necessitate comprehensive person-centred management, including non-pharmacological approaches. Recommendations for non-pharmacological management are currently lacking.ObjectivesTo perform a systematic literature review to inform the EULAR task force for recommendations/points to consider for the non-pharmacological management of adult patients with SLE and SSc. Among research questions formulated by the task force, we aimed at identifying (i) non-pharmacological interventions that have been evaluated and (ii) their target health domains or organ systems.MethodsWe searched the Medline, Embase, Web of Science Core Collection and CINAHL for articles published between January 2000 and June 2021. From the initial search (n=15,803), 2 researchers independently performed the article selection. Conflicts were discussed until consensus with 2 additional researchers. Subsequent data extraction from the selected articles was performed by 4 researchers, with an overarching guidance by 2 additional researchers. Risk of bias assessment was performed according to Joanna Briggs Institute Critical Appraisal Checklists.ResultsA total of 111 articles for SLE and 75 for SSc were selected for analysis.Non-pharmacological interventions identified for SLE included physical exercise (n=34), psychological support (n=21), dietary therapy and nutrition (n=15), patient education and self-management (n=14), photoprotection (n=5), medication adherence interventions (n=5), complementary and alternative medicine (CAM) e.g., Chinese medicine (n=5), multidisciplinary care (n=4), and phototherapy/laser modalities (n=4).Interventions identified for SSc included physical exercise e.g., hand, oral and general exercise (n=21), phototherapy/laser modalities or shockwave therapy (n=15), patient education and self-management (n=10), CAM (n=8), hand-bathing e.g., in paraffin (n=5), manual therapy e.g., osteopathic manipulative treatment (n=5), dietary therapy and nutrition (n=5), oral hygiene (n=2), hyperbaric oxygen or ozone therapy (n=2) and multidisciplinary care (n=2).Target health domains and organ systems identified within SLE included (in descending order) (i) disease activity, (ii) health-related quality of life (HRQoL), (iii) depression/anxiety, (iv) fatigue, (v) organ damage, (vi) inflammatory markers, (vii) psychological stress, (viii) pain, (ix) body composition/anthropometry, and (x) aerobic capacity.Intervention targets in SSc included (i) functional impairment e.g., hand mobility, (ii) skin sclerosis including microstomia, (iii) HRQoL, (iv) pain, (v) circulation e.g., Raynaud’s phenomena and telangiectasias, (vi) skin ulcers, (vii) oral hygiene, (viii) fatigue, (ix) digestion, and (x) depression/anxiety.ConclusionPhysical exercise was a frequently researched non-pharmacological intervention within both SLE and SSc. While psychological support and dietary therapy/nutrition were frequently investigated in SLE, phototherapy modalities were common in SSc. Patient education and self-management was advocated in both SLE and SSc literature. HRQoL was a frequent target domain in both diseases; while disease activity and psychosocial domains emerged as important targets in SLE, functional impairment and skin-related aspects constituted predominant targets in SSc. Efficacy of interventions varied considerably across studies. Current evidence is limited by the overall small study populations, and the lack of large RCTs.Table 1.Studies categorised by design.Study designSLESScMeta-analysis of RCTs51RCT (including long-term follow-up or post-hoc analysis)4128Non-randomised longitudinal controlled/cohort studies287Retrospective cohort study, cross-sectional or case-control study162Case series or open pilot studies2137AcknowledgementsThe authors would like to thank the members of the EULAR task force for recommendations/points to consider for the non-pharmacological management of systemic lupus erythematosus and systemic sclerosis (in alphabetical order by family name) i.e., Helene Alexanderson, Laurent Arnaud, Oliver Distler, Andrea Domján, Els van den Ende, Kim Fligelstone, Agnes Kocher, Maddalena Larosa, Martin Lau, Alexandros Mitropoulos, Mwidimi Ndosi, Gunilla von Perner, Janet Poole, Anthony Redmond, Valentin Ritschl, Yvonne Sjöberg, Tillmann Uhlig, Cecília Varjú, Joke Vriezekolk, Elisabet Welin, and Rene Westhovens, for their contribution to the formulation of the research questions together with IP, CG, TS and CB.Disclosure of InterestsNone declared
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Shahanenko, R., N. Ilnitskiy, V. Shahanenko, and S. Rublenko. "Ozonetherapy as a new antimicrobic strategy." Naukovij vìsnik veterinarnoï medicini, no. 2(160) (November 24, 2020): 195–200. http://dx.doi.org/10.33245/2310-4902-2020-160-2-195-200.

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Development of antibiotic-resistant strains of microorganisms is a dangerous phenomenon, actively progressing every year. The uncontrolled use of antibiotics for animals, accumulation in products of animal origin ultimately poses a danger to human health. That is why a decrease in the use of antibiotics and searching alternatives of antibiotic is acute and relevant issues. Therefore, the aim of our research was to study the antimicrobial properties of ozone in relation to pathogens of purulent infection and to show the possibility of using ozone therapy as a potential method of antimicrobial therapy for animals. The materials for determining antimicrobial effect of ozone was 12 samples of purulent exudate in an amount of 2 ml, taken from dogs with purulent wounds before and after sanitation by ozonized 0.87% NaCl solution. Complexity course of wound process with purulent inflammation largely depends on from degree of microbial contamination of the wound and species composition of microorganisms. Therefore, an important aspect in our research was the study of the antimicrobial properties of ozone on its action of purulent exudate «in vitro» and «in vivo» and the determination of the bactericidal effect on microorganisms. The most stable and informative indicator of assessing nature of purulent-inflammatory process is the determination of total number of microorganisms in 1 ml of discharge from a purulent wound. The total microbial number was determined by the method of serial dilutions according to Pasteur. Serial ten-fold dilutions from 10-1 to 10-9 were prepared from purulent exudate in test tubes with sterile MPB (9 ml each). Species composition of microorganisms was determined by cultural and biochemical properties of cultivated microbial colonies, followed microscopy of smears from pure cultures stained using method of Gram. Samples of purulent exudate were subjected to microbiological examination before treatment, and after 30 minutes of washing by ozonized isotonic solution NaCl (ozone concentration of 7 mg/ml). A microbiological study of purulent exudate was also carried out, pre-treated with ozone at a concentration of 7 mg/ml «in vitro» in a test tube in an amount of 2 ml by passing it through exudate (sparging) at a flow rate of 0.5 L/min and a processing time of 10 min. Samples were examined immediately after sampling and sparging. "Microbial landscapes" of purulent wounds were presented by associations of Staph. aureus, Str. faecalis, E. coli. Microbial seeding of purulent exudate for treatment ranged from 6.6 • 10-10 to 3.7 • 10-8 CFU/ml, however, after 10 min of bubbling «in vitro» at an ozone concentration of 7 mg/ml, the degree of microbial seeding of samples did not exceed 10-4 CFU/ml and ranged from 3.1 • 10-4 to 2.3• 10-3 CFU/ml. As shown by the results of microbiological studies, the growth of microorganisms on a nutrient medium in bacteriological plates with purulent exudate samples treated with ozone with concentration of 7 mg/ml was already absent at 10-5 degrees of dilution, which indicates the pronounced antimicrobial properties of ozone. The study «in vivo»also indicates that even after a single use of an ozonized isotonic NaCl solution at an ozone concentration of 7 mg/ml, it completely prevents the growth of Staph. aureus, Str. faecalis, E. coli. and causes 100% death mentioned associations of microorganisms. The results of microbiological studies are confirmed by clinical data. So, on the third day of treatment, the animals in the lesion zone had a small amount of wound exudate, and the microbial number of the latter was 1.4 • 10-4 − 3.1 • 10-³ CFU/ml, below the critical level of contamination and in most cases not leads to the progression of a purulent-inflammatory process. Ozone destroys all types of bacteria, viruses, fungi and protozoa. At the same time, ozone at a concentration of 7 mg/ ml does not have an irritating effect on body tissues, therefore, ozone therapy can be considered as an additional or alternative therapy of bacterial infection. Key words: ozone, ozonetherapy, purulent wounds, antibiotic resistance.
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Li, Wei, Qixing Zhou, and Tao Hua. "Removal of Organic Matter from Landfill Leachate by Advanced Oxidation Processes: A Review." International Journal of Chemical Engineering 2010 (2010): 1–10. http://dx.doi.org/10.1155/2010/270532.

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In most countries, sanitary landfill is nowadays the most common way to eliminate municipal solid wastes (MSWs). However, sanitary landfill generates large quantity of heavily polluted leachate, which can induce ecological risk and potential hazards towards public health and ecosystems. The application of advanced oxidation processes (AOPs) including ozone-based oxidation, Fenton oxidation, electrochemical oxidation, and other AOPs to treatment of landfill leachate was reviewed. The treatment efficiency in term of chemical oxygen demand (COD) of various AOPs was presented. Advantages and drawbacks of various AOPs were discussed. Among the AOPs reviewed, Fenton process should be the best choice, not only because it can achieve about 49~89% of COD removal with COD ranging from 837 to 8894 mg/L, but also because the process is cost-effective and simple in technological aspect, there is no mass transfer limitation (homogeneous nature) and both iron and hydrogen peroxide are nontoxic.
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DA SILVA, Paulo, Ikuo TANABE, Da Cruz R. JUNIOR, and Satoshi TAKAHASHI. "THE ANALYSIS OF ENVIRONMENTAL AND HUMAN IMPACTS OF USING STRONG ALKALINE WATER FOR COOLING DURING MACHINING." Journal of Machine Engineering Vol.18, No.1 (February 22, 2018): 33–45. http://dx.doi.org/10.5604/01.3001.0010.8821.

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An eco-friendly manufacturing approach is important for the environment. Enhancing machining performances is not only required to improve product’s quality, time saving, and reduces costs; it is also contributed to the environmental protection efforts. Cooling is important aspect for obtaining this purpose. Therefore the benefits of Strong Alkaline Water (SAW) cooling method was assessed and compared with conventional wet cutting method. An experiment was performed at Nagaoka University of Technology machining centre. Three machine tools including a milling machine, a drilling machine and a turning machine were used. The study shows that using SAW for cooling is far more efficient than conventional cooling method. It reduces annual global warming potential by 72.95%, acidification potential 98.18%, ozone depletion potential 99.6%, smog formation potential 85.71% and human toxicity potential 42.86% compare with conventional method. The study concludes that besides inhibiting corrosion, prolonging tool life, improving surface roughness of final cutting and reducing energy usage, strong alkaline water cooling is an environmentally friendly approach and has positive impact on human health.
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Mandal, Gopa Chandra. "Rethinking Corporate Social Responsibility in the Arena of Climate Change: A Study in Socio-Legal Aspect." Journal of Climate Change 8, no. 4 (December 5, 2022): 17–24. http://dx.doi.org/10.3233/jcc220026.

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Climate change is an environmental challenge confronting all countries across the globe in varying degrees of intensity. It, directly and indirectly, interferes with the enjoyment of all human beings including – the right to life, housing, water and sanitation, food, health, development, security of persons and an adequate standard of living. Industry and business play a crucial role with regard to climate change, accounting for approximately one-third of the world’s energy consumption and 36 per cent of carbon dioxide emissions. Therefore, industry and the global business community have a responsibility to join national and international efforts to lower their greenhouse gas emissions. Across Asia, Europe, Africa, and North and South America, the adverse effects of climate change have manifested over the years as ozone layer depletion, continental global warming, a shower of acid rain, extended fires, melting ice, rise in sea level and other extreme events which call for urgent action at national and international levels. A self-regulating approach that makes manufacturing organisations socially responsible and responsive to environmental issues in their operating countries can be pragmatic in climate-change mitigation, and strengthen existing governmental policies on climate change. A number of affirmative actions and recommendations has been formulated at national and international levels to regulate climate change including eco-vigilance, adoption of green, conservation of the flora and fauna, zero-tolerance of gas flaring, socially responsible investment, carbon emission reporting and disclosures and adoption of environment-friendly manufacturing techniques. Therefore, the present study not only focusses on the theoretical aspect but also on the socio-legal aspect filling the gap in both theory and practice related to the impact of Corporate Social Responsibility on society.
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Miao, Chunping, Wei Chen, and Shuai Yu. "Assessing Ozone Distribution Vertically and Horizontally in Urban Street Canyons Based on Field Investigation and ENVI-met Modelling." Buildings 12, no. 3 (February 24, 2022): 262. http://dx.doi.org/10.3390/buildings12030262.

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High concentrations of ozone (O3) is a major air problem in urban areas, which creates a serious threat to human health. Urban street canyon morphology plays a key role in air pollutant dispersion and photochemical reaction rate. In this study, a one-year observation at three height levels was performed to investigate the O3 distribution vertically in a street canyon of Shenyang. Then, field investigation and ENVI-met modelling were conducted to quantify the influence of street canyon morphology and microclimatic factors on O3 distribution at the pedestrian level. All O3 concentrations at the three height levels were high from 1:00 p.m. to 4:00 p.m. Both O3 concentrations at pedestrian level and the middle level in the canyon were 40% higher than at roof level. O3 accumulated in the canyons rather than spread out. The in-canyon O3 concentrations had significantly positive correlations with building height, aspect ratio, sky view factor, air temperature, and wind speed. Both field investigation and ENVI-met modelling found high O3 concentrations in medium canyons. Photochemical reaction intensity played a more important role in in-canyon O3 distribution than dispersion. Wide canyons were favorable for removing O3.
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Milanović, Tijana, Zdravka Petković, and Gordana Stojmenović. "THE IMPORTANCE AND THE ROLE OF INTRODUCTION OF ECOLOGICAL ACCOUNTING IN THE FUNCTION OF MANAGEMENT OF ENVIRONMENTAL PROTECTION." Knowledge International Journal 28, no. 1 (December 10, 2018): 171–75. http://dx.doi.org/10.35120/kij2801171m.

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More and more global warming, ozone depletion and loss of biodiversity have contributed to raising awareness of the need to implement measures that enable sustainable development, so that different pillars of society find a balance between economic growth and social interest in preserving a healthy environment. The environmental impacts of the company have led to the strengthening of environmental demands by society and the incorporation of various management tools into the environmental management process. In order to properly address the issue of environmental protection, a so-called environmental management system is required, which carries out an important part of the information systems management system in an integrated form, together with another accounting information system. Ecological accounting is an important tool for understanding the role of the natural environment in the economy. Environmental accounts provide data that highlight the contribution of natural resources to economic well-being and the costs of imposed pollution or resource degradation. The use of accounting in the environment is necessary with more aspects on various issues, such as cost estimates, investment analysis and strategic decision-making. Companies, which are important subjects of economic activity, play the main roles in economic activities. Therefore, a clear introduction of the goal of preserving the environment in every activity activity becomes a strong motivating force for the structural transformation of this economic society. This paper will present a brief overview of the history, concept, division, role, significance and contributions of ecological accounting, and the importance and necessity of introducing ecological accounting in enterprises.Given the financial implications that environmental impacts can have on the business of the company, this paper aims to point out the role and significance of environmental accounting and the environmental management process.
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Giuliani, Giuseppe, Giovanni Ricevuti, Antonio Galoforo, and Marianno Franzini. "Microbiological aspects of ozone: bactericidal activity and antibiotic/antimicrobial resistance in bacterial strains treated with ozone." Ozone Therapy 3, no. 3 (December 18, 2018). http://dx.doi.org/10.4081/ozone.2018.7971.

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Antimicrobial resistance is one of the most complex global health challenges today. The world has long ignored warnings that antibiotics and other medicines are losing their effectiveness after decades of overuse and misuse in human medicine, animal health and agriculture. Common illnesses like pneumonia, postoperative infections, diarrhoeal and sexually transmitted diseases, as well as the world’s largest infectious disease killers – tuberculosis (TB), HIV and malaria – are increasingly becoming untreatable because of the emergence and spread of drug resistance. Worsening antimicrobial resistance could have serious public health, economic and social implications. The threat of antimicrobial resistance is also becoming a key consideration for programmes addressing maternal and child health, sexual and reproductive health, foodborne diseases, water and sanitation, and infection prevention and control. Although the 21st century is being shaped by technology and innovation, humans could soon find themselves in an era where simple infections once again kill millions every year. The past three years have seen unprecedented global political momentum to address antimicrobial resistance: in 2015, governments adopted a global action plan at the World Health Assembly and in 2016 passed a political declaration at the United Nations General Assembly. Antimicrobial resistance has made it onto the agendas of the G7 and G20 groups and is a core component of the Global Health Security Agenda. WHO is working closely with the Food and Agriculture Organization of the United Nations and the World Organization for Animal Health in leading global efforts against antimicrobial resistance and ensuring that the necessary momentum is consolidated and sustained. These efforts are guided by an ad-hoc interagency coordination group established in 2017. A global development and stewardship framework to combat antimicrobial resistance is being drafted to support the development of new antimicrobial medicines, diagnostics, vaccines and other tools. One of the gravest global concerns about antimicrobial resistance currently is that antibiotic resistance has emerged in so many pathogens, including TB. In 2016, at the high-level meeting of the UN General Assembly on antimicrobial resistance, Heads of State directed an unprecedented level of attention to curbing the spread of infections that are resistant to antimicrobial medicines. They reaffirmed their commitment to stopping the misuse of antimicrobial medicines in human health, animal health and agriculture, and recognized the need for stronger systems to monitor drug-resistant infections and the amounts of antimicrobials used in humans and animals. In the wake of the increasing global awareness of the need for new antibiotics, Member States highlighted market failures, and called for new incentives for investment in research and development of new, effective and affordable medicines, rapid diagnostic tests, and other important therapies to replace those that are losing their effectiveness. In response to this and in line with the Global Action Plan on Antimicrobial Resistance to support the identification of pathogens of greatest concern, WHO developed a priority list of antibiotic resistant bacteria to underpin renewed efforts for the research and development of new antibiotics. The only possible defence against the threat of antimicrobial resistance and the (very real) possibility of a post-antibiotic era is a global and coordinated effort by all stakeholders to support other important therapies such as the Oxygen-Ozone (O2O3) therapy. As a result, the scope and focus of the work underlying this dissertation was to study the application of O2O3 therapy towards several resistant bacteria. Moreover, we evaluated three different framework for gut bacteria, skin and soft tissue infections and mucosal infections.
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König, Brigitte, and Johann Lahodny. "Ozone high dose therapy (OHT) improves mitochondrial bioenergetics in peripheral blood mononuclear cells." Translational Medicine Communications 7, no. 1 (July 21, 2022). http://dx.doi.org/10.1186/s41231-022-00123-7.

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Abstract Background The worldwide increasing number of people with chronic diseases is pushing conventional therapy to its limits. The so-called Major AutoHaemo Therapy (MAH) has been used in many practices for years. Despite suspicions, especially the 10-passes ozone-high-dosis Therapy (OHT) has shown substantial benefits in chronic ailments. However, knowledge of scientifically based effects of high ozone concentrations are still rare. The present investigation focussed on verifying whether OHT may be linked to a beneficial effect on mitochondrial bioenergetics which can be expressed as a bioenergetic health index (BHI). Methods We report on six patients which received OHT for preventive purposes twice within one week. The BHI in peripheral blood mononuclear cells (PBMC) is calculated from parameters of a cellular mitochondrial function assay, which gives insights into different aspects of mitochondrial function: 1) Basal oxygen consumption rate (OCR); 2) ATP-linked OCR and proton leak; 3) Maximal OCR and reserve capacity; 4) Non-mitochondrial OCR. Results The results clearly show that the bioenergetic health index in PBMC improves significantly after just 2 OHT applications over a period of 1 week. The overall improvement of the BHI is based primarily on a significant increase in the reserve capacity and the maximum respiration of the mitochondria. The increase in non-mitochondrial oxygen consumption, which has a negative impact on the BHI value, is indicative for the Nrf-2 dependent activation of antioxidant and detoxifying enzymes activated through OHT. Conclusion These data demonstrate for the first time the beneficial effect of OHT on mitochondrial parameters. Thus, the results of this study suggest that OHT could be a safe and effective therapeutic option alone or as integrative and complementary support for pharmacological therapy in a variety of chronic and acute diseases where mitochondrial dysfunction plays a central role.
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Damian Ezeonyejiaku, Chigozie, Charles Obinwanne Okoye, Nonye Juliana Ezeonyejiaku, and Maximilian Obinna Obiakor. "Air Quality in Nigerian Urban Environments: A Comprehensive Assessment of Gaseous Pollutants and Particle Concentrations." Current Applied Science and Technology 22, no. 5 (December 21, 2021). http://dx.doi.org/10.55003/cast.2022.05.22.011.

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The rise in gaseous pollutants and particulate concentrations is a serious problem for the environment. This study examined the air quality within four urban areas (Awka, Ekwulobia, Nnewi, and Onitsha) in Anambra State, Nigeria. The concentrations of known air pollutants including suspended particulate matter (PM2.5 and PM10), nitrogen dioxide (NO2), sulfur dioxide (SO2), methane (CH4), volatile organic compounds (VOCs), hydrogen sulfide (H2S), ammonia (NH3), ozone (O3), carbon dioxide (CO2) and carbon monoxide (CO) were assessed at various locations within the study areas using Aeroqual air quality monitoring devices, and the results were compared with the WHO air quality guidelines for health impact assessment. The air quality index (AQI) was interpolated from the pollutant concentrations in order to show hazard categories of air quality conditions over the study locations. The mean concentrations of SO2, CH4, and VOCs within the residential locations of Awka, Ekwulobia, and Nnewi were in the range of 200-8000 µg m-3 and exceeded WHO limits for air quality. While the levels of CO2, SO2, and CH4 (3.25-1,027,000 µg m-3) within the commercial locations of Awka, Ekwulobia, and Nnewi exceeded WHO limits, only VOCs (500-1100 µg m-3) within Awka and Ekwulobia exceeded the limits. The 62-181 µg m-3 and 40-295 µg m-3 ranges of PM2.5 and PM10, respectively within the Nnewi and Ekwulobia commercial locations were the only particle concentrations at which the World Health Organization (WHO) recommended limits for health aspects of air pollution were exceeded. The AQI calculations showed air quality within some of the locations may have potential risks for public health.
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Gavurova, Beata, Martin Rigelsky, and Viera Ivankova. "Greenhouse Gas Emissions and Health in the Countries of the European Union." Frontiers in Public Health 9 (December 10, 2021). http://dx.doi.org/10.3389/fpubh.2021.756652.

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In the current era of globalization, a clean environment remains a crucial factor for the health of the population. Thus, improving air quality is a major focus of environmental policies, as it affects all aspects of nature, including humans. For these reasons, it is appropriate to take into account the health risks posed by greenhouse gas (GHG) emissions released into the atmosphere. With regard to global GHG emissions, there are concerns about the loss of protection of the ozone layer and it is very likely that climate change can be expected, which multiplies the environmental threat and has potentially serious global consequences. In this regard, it is important to pay increased attention to emissions that enter the atmosphere, which include countless toxic substances. The aim of this study was to examine the associations between selected GHG emissions and the health of the European Union (EU) population represented by disability-adjusted life years (DALYs). This aim was achieved using several analytical procedures (descriptive analysis, correlation analysis, cluster analysis, and panel regression analysis), which included five environmental variables (carbon dioxide (CO2), methane (CH4) in CO2 equivalent, nitrous oxide (N2O) in CO2 equivalent, hydrofluorocarbons (HFC) in CO2 equivalent, sulfur hexafluoride (SF6) in CO2 equivalent) and one health variable (DALYs). An emphasis was placed on the use of quantitative methods. The results showed that CO2 emissions have a dominant position among selected GHG emissions. The revealed positive link between CO2 and DALYs indicated that a decrease in CO2 may be associated with a decrease in DALYs, but it is also true that this cannot be done without reducing emissions of other combustion products. In terms of CO2, the least positive scores were observed in Luxembourg and Estonia. Germany had the lowest score of DALYs, representing the most positive health outcome in the EU. In terms of total GHG emissions, Ireland and Luxembourg were considered to be less positive countries compared to the other analyzed countries. Countries should focus on reducing GHG emissions in general, but from a health point of view, reducing CO2 emissions seems to be the most beneficial.
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Fusco, V., A. Baraldi, A. Fasciolo, M. Rapetti, I. De Martino, L. Randi, A. Bedogni, A. Agrillo, and G. Campisi. "Osteonecrosis of jaw (onj): impact of italian patients, and role of italian physicians, dentists, and researchers in the growing evidence of a “new” disease." Working Paper of Public Health 1, no. 1 (June 15, 2012). http://dx.doi.org/10.4081/wpph.2012.6778.

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Purpose: Osteonecrosis of jaw (ONJ) is an uncommon but severe complication observed mostly in patients treated with bisphosphonates (BPs) for bone metastases, myeloma, osteoporosis (so called BRONJ, Bisphosphonate-Related Osteonecrosis of Jaw), but also with other drugs (bevacizumab, sunitinib, denosumab). The number of cases observed in Italy appears high in comparison with other countries and we present a review of several aspects of ONJ in Italy and the role of Italian health professionals and researchers on increasing knowledge and adequate reporting of ONJ phenomenon; Methods: Literature review about osteonecrosis of jaw (ONJ) with selection of Italian authors and publications, on year 2003-2011, by research on international electronic journal databases, Italian language journals, congress acta, web sources; Results: at October 2011, among 1272 papers published worldwide on ONJ issue, 128 (10%) were from Italian Authors; Conclusions: relevant articles by Italian groups were published about pathogenesis hypotheses, animal models, biology studies, risk factors, preventive measures, dental extraction protocols in BP-exposed patients, laser therapy, ozone therapy, surgical treatment. Experience of Italian patients suffering from ONJ, together with work of Italian dentists, physicians and researchers, appears of paramount importance in order to study ONJ and minimize a possible severe side-effect of efficacious medical treatments.
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