Academic literature on the topic 'Ovaries'

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Journal articles on the topic "Ovaries"

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Berger, Bruno, Silvana B. Poiani, Thaisa C. Roat, and Carminda da Cruz-Landim. "Ovary Development in Honeybee (Apis Mellifera L.) Workers Under Co2 Narcosis, Caged Outside of the Colony." Journal of Apicultural Science 59, no. 1 (June 1, 2015): 51–58. http://dx.doi.org/10.1515/jas-2015-0004.

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Abstract Exposure of A. mellifera workers to CO2 has been reported to decrease life span, induce behavioral changes, and inhibit the development of some glands and the ovaries. However, the use of CO2 is currently practiced among beekeepers and how the development of workers’ ovaries are affected is unknown. The present work aimed to evaluate the effect of CO2 on the ovaries of A. mellifera workers, using a morphological approach. Newly emerged, and 3, 5, and 10-day-old workers were exposed to saturated CO2 for 30 seconds, more than once. The ovaries were examined under light (LM) and transmission electron microscopy (TEM). The ovaries of narcotized, 5-day-old workers exhibited long ovarioles with well-developed germarium, although oogenesis showed little development. While in the control group, the ovaries already exhibited cysts with cystocytes forming rosettes. At 10-days-old, the ovaries feature was variable; some of the ovaries showed ovarioles with many rosette cysts while others showed a high intensity of disorganization due to the beginning of cell death. The ovarioles of the ovaries of 15-day-old treated workers were morphologically varied as oogenesis showed little or no advance. In others cases, a complete disorganization with swollen cells and cell death features were observed. Germ cells of the ovaries of CO2-treated workers exhibited well-structured organelles, such as the Golgi complex, and larger amounts of mitochondria in the cytoplasm than the control group, but there was disorganization of the endoplasmic reticulum membranes. Our findings revealed that the exposure of workers to CO2 promotes impairment of oogenesis and ovarian degradation.
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Borges, Á. M., C. H. Santana, and R. L. Santos. "Squamous metaplasia of the rete ovarii do not suppress ovarian cyclicity and pregnancy in cattle: case report." Arquivo Brasileiro de Medicina Veterinária e Zootecnia 73, no. 3 (May 2021): 653–57. http://dx.doi.org/10.1590/1678-4162-12221.

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ABSTRACT Squamous metaplasia of the rete ovarii is an ovarian pathologic change characterized by replacement of the normal single layered cuboidal epithelium of the rete ovarii by a stratified squamous keratinized epithelium. Uterus and ovaries from a local slaughterhouse pregnant crossbreed cow were evaluated through ultrasound, macroscopically and histologically. Grossly, there were multiple cysts in both ovaries, which were histologically characterized as rete ovarii cysts with squamous metaplasia and intraluminal accumulation of keratinized material. Squamous metaplasia of the rete ovarii has been previously reported in cows, however this is the first report of this condition in a pregnant animal, demonstrating that this ovarian change is compatible with pregnancy.
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Suzuki, O., M. Koura, Y. Noguchi, K. Uchio-Yamada, and J. Matsuda. "77 SUCCESSFUL CRYOPRESERVATION OF SYRIAN HAMSTER OVARIES BY VITRIFICATION." Reproduction, Fertility and Development 21, no. 1 (2009): 139. http://dx.doi.org/10.1071/rdv21n1ab77.

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In place of gametes, ovaries can be used as an alternative resource for cryopreservation. At the previous IETS meeting, we showed that in the Syrian hamster, pups could be successfully produced through the transplantation of fresh ovaries. In addition, the immunotolerance of interstrain ovarian transplantation was described. In this study, we attempted to produce pups via transplantation of cryopreserved ovaries to foster mothers. Our goal was to establish a preservation method for hamster strains based on ovarian cryopreservation in combination with ovarian transfer. Ovaries were cryopreserved by vitrification according to methods described for mouse ovaries (Migishima F et al. 2003 Biol. Reprod. 68, 881–887). In brief, ovaries were collected from 2- to 3-week-old HAW strain (white coat) females. Each ovary was cut into 4 sections, placed into 1 tube, and cryopreserved by vitrification using DAP213 solution (2 m dimethyl sulfoxide, 1 m acetamide, and 3 m propylene glycol; Nakagata N 1989 J. Reprod. Fertil. 87, 479–483). Thawed ovaries were transferred into the ovarian bursae (2 ovarian sections per ovarian bursa) of 3-week-old recipient females with agouti coat (Slc:Syrian) under anesthesia with isoflurane. Half of the recipients’ ovaries were removed immediately before transfer; i.e. both donor and recipient ovaries were present in each ovarian bursa. Successful ovarian transplantation was verified by examining the coat color (non-agouti color) of offspring produced in test matings between mature recipients and Slc:Syrian males. Out of 6 recipients tested, 2 became pregnant and delivered pups. According to the coat color of the pups, 1 of the 2 recipients delivered a pup produced from transplanted ovaries (1 out of 4 pups). Regardless of this low success rate, our results indicate that pups can be produced from cryopreserved ovaries via interstrain transplantation of ovaries to foster mothers in the Syrian hamster. Thus, ovarian cryopreservation by vitrification is a promising strategy for strain preservation of the Syrian hamster. This work was supported by a grant from the Ministry of Health, Labor, and Welfare, Japan.
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Suzuki, O., M. Koura, Y. Noguchi, K. Uchio-Yamada, and J. Matsuda. "94 EFFECT OF OVARIAN SIZE ON THE VIABILITY OF CRYOPRESERVED SYRIAN HAMSTER OVARIES." Reproduction, Fertility and Development 23, no. 1 (2011): 152. http://dx.doi.org/10.1071/rdv23n1ab94.

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Ovaries can be used in place of gametes as a resource for cryopreservation. Thus far, we have shown that in the Syrian hamster, pups can be successfully produced through the transplantation of fresh and cryopreserved ovaries. In this study, we attempted to simplify the ovarian cryopreservation procedures to facilitate the easy application of these techniques. In particular, the procedure would be easier and quicker if the ovaries did not have to be cut into small pieces before ovarian cryopreservation. Therefore, we examined the effects of ovarian fragment size on subsequent offspring production. Ovaries were cryopreserved by vitrification according to methods described for mouse ovaries (Migishima et al. 2003 Biol. Reprod. 68, 881–887). In brief, ovaries were collected from 3-week-old J2N-n strain (white coat) females. Because we had previously confirmed that quarter-sized ovaries could be used for cryopreservation, intact (∼3.5 × 2 mm) and half-sliced ovaries (∼2 × 1.5 mm) were cryopreserved by vitrification using DAP213 solution (2 M dimethyl sulfoxide, 1 M acetamide, and 3 M propylene glycol; Nakagata 1989 J. Reprod. Fertil. 87, 479–483). Thawed ovaries were transferred into the ovarian bursae (single intact ovary or two half-sliced ovarian pieces per ovarian bursa) of 3-week-old recipient females with agouti-coat (Slc:Syrian) under isoflurane anaesthesia. Not all of the recipients’ ovaries were removed immediately before transfer; both the donor’s and a small portion of the recipient’s ovaries were present in each ovarian bursa. Successful ovarian transplantation was verified by examining the coat colour (non-agouti colour) of offspring produced in test matings between mature recipients and J2N-n males. Of the 3 and 6 recipients that received intact and sliced ovaries, respectively, 2 and 5 recipients delivered pups. Based on the coat colour of the pups, 1 of the 5 recipients delivered a pup produced from transplanted half-sliced ovaries. Our results indicate that half-sliced-size ovaries (smaller than a 2-mm cube) can be successfully used for cryopreservation in the Syrian hamster. Specifically, it is not required to slice the ovary into smaller pieces. This work was supported by a grant from the Ministry of Health, Labour and Welfare, Japan and Grant-in-Aid for Scientific Research (C).
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Keller, L. S. F., J. W. Griffith, and C. M. Lang. "Reproductive Failure Associated with Cystic Rete Ovarii in Guinea Pigs." Veterinary Pathology 24, no. 4 (July 1987): 335–39. http://dx.doi.org/10.1177/030098588702400408.

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Cystic ovaries were found at necropsy in 54 of 71 (76%) female guinea pigs between 18 and 60 months of age. Histologic appearance and location of the cysts within the ovary were consistent with cystic rete ovarii. Microscopic appearance of the large ovarian cysts suggested reproductive performance in these guinea pigs should be compromised. Breeding records indicated that fertility was markedly reduced in affected females over fifteen months of age. Cystic endometrial hyperplasia, mucometra, endometritis in appropriate placental tissue, or fibroleiomyomas were seen in 21 of 54 (39%) guinea pigs with cystic ovaries, but in only one of 17 (6%) guinea pigs without cystic ovaries.
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Chakravarthi, V. Praveen, Iman Dilower, Subhra Ghosh, Shaon Borosha, Ryan Mohamadi, Vinesh Dahiya, Kevin Vo, et al. "ERβ Regulation of Indian Hedgehog Expression in the First Wave of Ovarian Follicles." Cells 13, no. 7 (April 6, 2024): 644. http://dx.doi.org/10.3390/cells13070644.

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Increased activation of ovarian primordial follicles in Erβ knockout (ErβKO) rats becomes evident as early as postnatal day 8.5. To identify the ERβ-regulated genes that may control ovarian primordial follicle activation, we analyzed the transcriptome profiles of ErβKO rat ovaries collected on postnatal days 4.5, 6.5, and 8.5. Compared to wildtype ovaries, ErβKO ovaries displayed dramatic downregulation of Indian hedgehog (Ihh) expression. IHH-regulated genes, including Hhip, Gli1, and Ptch1, were also downregulated in ErβKO ovaries. This was associated with a downregulation of steroidogenic enzymes Cyp11a1, Cyp19a1, and Hsd17b1. The expression of Ihh remained very low in ErβKO ovaries despite the high levels of Gdf9 and Bmp15, which are known upregulators of Ihh expression in the granulosa cells of activated ovarian follicles. Strikingly, the downregulation of the Ihh gene in ErβKO ovaries began to disappear on postnatal day 16.5 and recovered on postnatal day 21.5. In rat ovaries, the first wave of primordial follicles is rapidly activated after their formation, whereas the second wave of primordial follicles remains dormant in the ovarian cortex and slowly starts activating after postnatal day 12.5. We localized the expression of Ihh mRNA in postnatal day 8.5 wildtype rat ovaries but not in the age-matched ErβKO ovaries. In postnatal day 21.5 ErβKO rat ovaries, we detected Ihh mRNA mainly in the activated follicles in the ovaries’ peripheral regions. Our findings indicate that the expression of Ihh in the granulosa cells of the activated first wave of ovarian follicles depends on ERβ.
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Boqun, Xu, Dai Xiaonan, Cui YuGui, Gao Lingling, Dai Xue, Chao Gao, Diao Feiyang, et al. "Expression of SET Protein in the Ovaries of Patients with Polycystic Ovary Syndrome." International Journal of Endocrinology 2013 (2013): 1–5. http://dx.doi.org/10.1155/2013/367956.

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Background. We previously found that expression of SET gene was up-regulated in polycystic ovaries by using microarray. It suggested that SET may be an attractive candidate regulator involved in the pathophysiology of polycystic ovary syndrome (PCOS). In this study, expression and cellular localization of SET protein were investigated in human polycystic and normal ovaries.Method. Ovarian tissues, six normal ovaries and six polycystic ovaries, were collected during transsexual operation and surgical treatment with the signed consent form. The cellular localization of SET protein was observed by immunohistochemistry. The expression levels of SET protein were analyzed by Western Blot.Result. SET protein was expressed predominantly in the theca cells and oocytes of human ovarian follicles in both PCOS ovarian tissues and normal ovarian tissues. The level of SET protein expression in polycystic ovaries was triple higher than that in normal ovaries(P<0.05).Conclusion. SET was overexpressed in polycystic ovaries more than that in normal ovaries. Combined with its localization in theca cells, SET may participate in regulating ovarian androgen biosynthesis and the pathophysiology of hyperandrogenism in PCOS.
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Suzuki, O., M. Koura, K. Takano, Y. Noguchi, K. Uchio-Yamada, and J. Matsuda. "148 PRODUCTION OF PUPS BY OVARIAN TRANSFER IN THE SYRIAN HAMSTER." Reproduction, Fertility and Development 20, no. 1 (2008): 154. http://dx.doi.org/10.1071/rdv20n1ab148.

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Instead of gametes, ovaries could be used as alternative resources for cryopreservation. In this study, we attempted to produce pups by transplantation of fresh ovaries to foster mothers as a first step to establish a preservation method of hamster strains on the basis of the cryopreservation of ovaries in combination with ovarian transfers. We also checked the possibility of inter-strain transfers of ovaries, since immunological tolerance among hamster strains is suggested by the fact that most Syrian hamsters were derived from only a small number of animals. Fresh ovaries collected from 3-weekold females of HAW (white coat) and APA (albino) strains were transferred into ovarian bursae of 3-week-old recipient females with agouti-coat (Slc:Syrian) under anesthesia with xylazine and ketamine. Halves of ovaries of recipients were removed immediately before the transfers, i.e., both donor and recipient ovaries were present in each ovarian bursa. Successful transplantation of ovaries was checked by the coat color (non-agouti color) of offspring produced by test matings of recipients with Slc:Syrian males after the recipients became mature. Five and six recipients received HAW and APA ovaries, respectively. All 11 recipients tested became pregnant and delivered pups. According to the coat color of the pups, three of five recipients which received HAW ovaries and one of six recipients which received APA ovaries delivered pups derived from transplanted ovaries (two out of eight pups, one out of seven pups, and three out of 11 pups for HAW; one out of five pups for APA). Our results indicate that transplantation of fresh ovaries to foster mothers could be used for production of pups from grafted ovaries in the Syrian hamster. In particular, immunological tolerance for ovarian transfers among at least three strains suggests that recipient strains might not need to be the same as donor strains for practical ovarian transfers in the Syrian hamster. Our results would facilitate the development of a strain preservation system for the Syrian hamster based on ovarian cryopreservation. This work was supported by a grant from the Ministry of Health, Labor, and Welfare of Japan.
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Kim, Yu Jin, Yong Il Cho, Ju Yi Jang, Yun Dong Koo, Sung Woon Park, and Jae Ho Lee. "Lovastatin, an Up-Regulator of Low-Density Lipoprotein Receptor, Enhances Follicular Development in Mouse Ovaries." International Journal of Molecular Sciences 24, no. 8 (April 14, 2023): 7263. http://dx.doi.org/10.3390/ijms24087263.

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Ovarian aging hampers in vitro fertilization in assisted reproductive medicine and has no cure. Lipoprotein metabolism is associated with ovarian aging. It remains unclear how to overcome poor follicular development with aging. Upregulation of the low-density lipoprotein receptor (LDLR) enhances oogenesis and follicular development in mouse ovaries. This study investigated whether upregulation of LDLR expression using lovastatin enhances ovarian activity in mice. We performed superovulation using a hormone and used lovastatin to upregulate LDLR. We histologically analyzed the functional activity of lovastatin-treated ovaries and investigated gene and protein expression of follicular development markers, using RT-qPCR and Western blotting. Histological analysis showed that lovastatin significantly increased the numbers of antral follicles and ovulated oocytes per ovary. The in vitro maturation rate was 10% higher for lovastatin-treated ovaries than for control ovaries. Relative LDLR expression was 40% higher in lovastatin-treated ovaries than in control ovaries. Lovastatin significantly increased steroidogenesis in ovaries and promoted the expression of follicular development marker genes such as anti-Mullerian hormone, Oct3/4, Nanog, and Sox2. In conclusion, lovastatin enhanced ovarian activity throughout follicular development. Therefore, we suggest that upregulation of LDLR may help to improve follicular development in clinical settings. Modulation of lipoprotein metabolism can be used with assisted reproductive technologies to overcome ovarian aging.
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Modina, Silvia C., Irene Tessaro, Valentina Lodde, Federica Franciosi, Davide Corbani, and Alberto M. Luciano. "Reductions in the number of mid-sized antral follicles are associated with markers of premature ovarian senescence in dairy cows." Reproduction, Fertility and Development 26, no. 2 (2014): 235. http://dx.doi.org/10.1071/rd12295.

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High-producing dairy cows are subfertile; however, the mechanisms responsible for the decreased fertility are unknown. The aim of the present study was to test the hypothesis that culled dairy cows (4–8 years old) characterised by ‘Lo’ ovaries (i.e. those with <10 mid-antral follicles) are affected by premature ovarian senescence. Cows in which both ovaries were ‘Lo’ ovaries represented 5% of the total population analysed, and exhibited reduced ovarian size (P < 0.001) and increased perifollicular stroma (P < 0.05) compared with age-matched controls (i.e. cows in which both ovaries had >10 mid-antral follicles; ‘Hi’ ovaries). The total number of follicles, including healthy and atretic primordial, primary, secondary and small antral follicles, was lower in Lo ovaries (P < 0.01). Interestingly, the primordial follicle population in Lo ovaries was lower (P < 0.05) than in the control. Finally, the follicular fluid of mid-antral follicles from Lo ovaries had reduced oestradiol and anti-Müllerian hormone levels (P < 0.05), but increased progesterone concentrations (P < 0.05). Together, these data account for the reduced fertility of cows with Lo ovaries and are in agreement with previous observations that oocytes isolated from Lo ovaries have reduced embryonic developmental competence. Cows with a specific Lo ovary condition may represent a suitable model to address the causes of low fertility in high-yielding dairy cows, as well as the condition of premature ovarian aging in single-ovulating species.
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Dissertations / Theses on the topic "Ovaries"

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Drake, Jeremy. "The expression and function of secreted frizzled-related protein 4 in human serous ovarian carcinoma /." Connect to this title, 2006. http://theses.library.uwa.edu.au/adt-WU2007.0072.

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Lam, Bing-shing. "Genetic study of borderline and invasive ovarian cancer." Hong Kong : University of Hong Kong, 2001. http://sunzi.lib.hku.hk/hkuto/record.jsp?B23668106.

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Siebert, Tiago Henrique Rodrigues [UNESP]. "Dinâmica e imuno-histoquímica da vitelogênese durante processo de maturação ovariana no camarão Xiphopenaeus kroyeri (Heller, 1862)." Universidade Estadual Paulista (UNESP), 2015. http://hdl.handle.net/11449/143012.

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Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
O camarão-sete-barbas Xiphopenaeus kroyeri está entre as espécies de crustáceos mais importantes do litoral brasileiro, com destaque social, econômico, ambiental e cultural. Além disso, destaca-se a ampla distribuição geográfica no litoral Atlântico Ocidental (Rio Grande de Sul - BR até a Carolina do Norte - EUA). Também evidencia-se o aumento da captura, com consequente diminuição dos estoques naturais. A falta de conhecimento sobre a biologia das espécies, principalmente aquelas visadas pelas frotas pesqueiras, diminui a eficiência de aplicações de medidas para proteção dos estoques naturais. O conhecimento sobre a dinâmica reprodutiva de uma espécie pode ser considerado importante e eficaz para controlar uma população explorada. Com relação aos crustáceos, o ciclo reprodutivo apresenta ovários em diferentes estágios de maturação e a determinação destes estágios envolve as atividades inerentes ao ovário e ao hepatopâncreas. Estes dois órgãos trabalham de forma sincronizada durante a vitelogênese. Assim, o objetivo deste estudo foi reavaliar alguns pontos referente a dinâmica celular em fêmeas de Xiphopenaeus kroyeri nos diferentes estágios de maturação ovariana. A classificação macroscópica e microscópica da maturação ovariana e o perfil celular dos túbulos hepatopancreáticos foram estudados através de análises histológicas e histoquímicas; a localização da síntese de vitelogenina no ovário e hepatopâncreas foi estudada através da imuno-histoquímica; e os índices gonadossomático (IGS) e hepatossomático (IHS) foram comparados. Deste modo, o ovário de X. kroyeri apresenta seis estágios de maturação: imaturo, pré-maturo, maturação inicial, maturação avançada, maduro e desovado. As células germinativas apresentam seis fases de desenvolvimento: oogônia tipo I, oogônia tipo II, oócitos pré-vitelogênicos, oócitos em vitelogênese inicial, oócitos em...
The shrimp Xiphopenaeus kroyeri is among the most important shellfish species off the Brazilian coast, with several highlights such as social, economic, environmental and cultural. In addition, we highlight the wide geographic distribution in the western Atlantic coast (Rio Grande do Sul - BR to North Carolina - USA) and also the increase in artisanal fisheries with consequent reduction of the natural stocks. The lack of knowledge about the biology of the species, especially those targeted by fishing fleets, decreases the efficiency of strategies for protection of natural stocks. Knowledge about reproductive dynamics of a species is considered important and effective to control an exploited population. Regarding the crustaceans, the reproductive cycle is composed of ovaries at different stages of maturation, and the determination of these stages involves activities related to the ovary and hepatopancreas. These two organs work synchronously during vitellogenesis. The objectives of this study were to reevaluate some points in females in different stages of ovarian maturation. Macroscopic and microscopic classification of ovarian maturation and the cellular profile of hepatopancreatic tubules were studied by histological and histochemical analyzes; the location of vitellogenin synthesis in ovary and hepatopancreas was studied by immunohistochemistry and the gonadosomatic (GSI) and hepatosomatic (IHS) indices were compared. Thus, X. kroyeri ovary features six maturity stages: immature, pre-mature, early maturation, advanced maturation, mature and spawned. The germ cells exhibit six phases of development: oogonia type I, oogonia type II, pre-vitellogenic oocytes, oocytes in early vitellogenesis, oocytes in advanced vitellogenesis and mature oocyte. The hepatopancreatic tubule is lined by a pseudostratified epithelium with five cell types, cell E (undifferentiated) cells F (fibrillar), cell R (resorptive), B cell (vesicular) and cell M ...
CNPq: 140453/2013-0
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Siebert, Tiago Henrique Rodrigues. "Dinâmica e imuno-histoquímica da vitelogênese durante processo de maturação ovariana no camarão Xiphopenaeus kroyeri (Heller, 1862) /." Jaboticabal, 2015. http://hdl.handle.net/11449/143012.

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Orientador: Irene Bastos Franceschini Vicentini
Banca: Bruno César Schimming
Banca: Fernanda Antunes Alves da Costa
Banca: Luciene Patrici Papa
Banca: Maria Terezinha Siqueira Bombonato
Resumo: O camarão-sete-barbas Xiphopenaeus kroyeri está entre as espécies de crustáceos mais importantes do litoral brasileiro, com destaque social, econômico, ambiental e cultural. Além disso, destaca-se a ampla distribuição geográfica no litoral Atlântico Ocidental (Rio Grande de Sul - BR até a Carolina do Norte - EUA). Também evidencia-se o aumento da captura, com consequente diminuição dos estoques naturais. A falta de conhecimento sobre a biologia das espécies, principalmente aquelas visadas pelas frotas pesqueiras, diminui a eficiência de aplicações de medidas para proteção dos estoques naturais. O conhecimento sobre a dinâmica reprodutiva de uma espécie pode ser considerado importante e eficaz para controlar uma população explorada. Com relação aos crustáceos, o ciclo reprodutivo apresenta ovários em diferentes estágios de maturação e a determinação destes estágios envolve as atividades inerentes ao ovário e ao hepatopâncreas. Estes dois órgãos trabalham de forma sincronizada durante a vitelogênese. Assim, o objetivo deste estudo foi reavaliar alguns pontos referente a dinâmica celular em fêmeas de Xiphopenaeus kroyeri nos diferentes estágios de maturação ovariana. A classificação macroscópica e microscópica da maturação ovariana e o perfil celular dos túbulos hepatopancreáticos foram estudados através de análises histológicas e histoquímicas; a localização da síntese de vitelogenina no ovário e hepatopâncreas foi estudada através da imuno-histoquímica; e os índices gonadossomático (IGS) e hepatossomático (IHS) foram comparados. Deste modo, o ovário de X. kroyeri apresenta seis estágios de maturação: imaturo, pré-maturo, maturação inicial, maturação avançada, maduro e desovado. As células germinativas apresentam seis fases de desenvolvimento: oogônia tipo I, oogônia tipo II, oócitos pré-vitelogênicos, oócitos em vitelogênese inicial, oócitos em...
Abstract: The shrimp Xiphopenaeus kroyeri is among the most important shellfish species off the Brazilian coast, with several highlights such as social, economic, environmental and cultural. In addition, we highlight the wide geographic distribution in the western Atlantic coast (Rio Grande do Sul - BR to North Carolina - USA) and also the increase in artisanal fisheries with consequent reduction of the natural stocks. The lack of knowledge about the biology of the species, especially those targeted by fishing fleets, decreases the efficiency of strategies for protection of natural stocks. Knowledge about reproductive dynamics of a species is considered important and effective to control an exploited population. Regarding the crustaceans, the reproductive cycle is composed of ovaries at different stages of maturation, and the determination of these stages involves activities related to the ovary and hepatopancreas. These two organs work synchronously during vitellogenesis. The objectives of this study were to reevaluate some points in females in different stages of ovarian maturation. Macroscopic and microscopic classification of ovarian maturation and the cellular profile of hepatopancreatic tubules were studied by histological and histochemical analyzes; the location of vitellogenin synthesis in ovary and hepatopancreas was studied by immunohistochemistry and the gonadosomatic (GSI) and hepatosomatic (IHS) indices were compared. Thus, X. kroyeri ovary features six maturity stages: immature, pre-mature, early maturation, advanced maturation, mature and spawned. The germ cells exhibit six phases of development: oogonia type I, oogonia type II, pre-vitellogenic oocytes, oocytes in early vitellogenesis, oocytes in advanced vitellogenesis and mature oocyte. The hepatopancreatic tubule is lined by a pseudostratified epithelium with five cell types, cell E (undifferentiated) cells F (fibrillar), cell R (resorptive), B cell (vesicular) and cell M ...
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Ratanasiri, Amornrat. "The outcome of primary treatment for ovarian cancer patients at srinagarind hospital during 1985-1989." Thesis, Hong Kong : University of Hong Kong, 1996. http://sunzi.lib.hku.hk/hkuto/record.jsp?B17538014.

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Hague, W. M. "Familial aspects of polycystic ovaries." Thesis, University of Cambridge, 1988. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.599834.

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Hao, Da Peng. "Integrated analysis of ovarian cancer :implications on tissue origin, hormone therapy and immunotherapy." Thesis, University of Macau, 2018. http://umaclib3.umac.mo/record=b3953959.

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Silva, Rafaela Nunes da [UNESP]. "Dinâmica da vitelogênese durante a maturação ovariana em Artemesia longinaris." Universidade Estadual Paulista (UNESP), 2014. http://hdl.handle.net/11449/116047.

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Sabe-se que em camarões peneídeos, a vitelogenina é sintetizada no ovário e hepatopâncreas, mas a contribuição relativa desses dois tecidos na síntese de vitelogenina ainda é incerta. Este processo pode diferir ainda de acordo com a espécie e estágio vitelogênico ou muda. Assim o presente estudo analisou a localização da produção de vitelogenina através de técnicas imunohistoquímicas, bem como, a quantificação do seu mRNA através do Real Time PCR em fêmeas de Artemesia longinaris em diferentes estágios de maturação ovariana (rudimentar - RU, em maturação - EM e maduro - MA). A espécie de camarão estudada apresenta altíssimo valor econômico. Assim, o estudo dos mecanismos da reprodução podem gerar dados para futuros projetos de produção em escala comercial, contribuindo com a preservação dos estoques naturais. A partir de análises moleculares confirmou-se a síntese de vitelogenina no ovário e hepatopâncreas de fêmeas de A. longinaris durante a maturação ovariana. Os níveis de expressão relativa de transcritos de vitelogenina no ovário e no hepatopâncreas durante a maturação ovariana demonstram que a dinâmica da síntese de vitelogenina é inversamente proporcional. A imunohistoquímica localizou a síntese endógena de vitelogenina nas células foliculares, nos oócitos pré-vitelogênicos e oócitos em vitelogênese inicial. E a síntese exógena de vitelogenina foi localizada nas células R dos túbulos hepatopancreáticos. Ainda, visto a grande contribuição do hepatopâncreas ao ciclo reprodutivo e às demais funções fisiológicas do animal, analisou-se o perfil celular do túbulo hepatopancreático nos estágios de maturação ovariana. Este órgão apresenta comportamento celular que se adapta ao ciclo reprodutivo em fêmeas, ou seja, o ciclo celular do hepatopâncreas além de obedecer a um ciclo digestivo é adaptado ao ciclo reprodutivo
It is known that in penaeid shrimp the vitellogenin is synthesized into the ovary and hepatopancreas, but the relative contribution of these two tissues in the synthesis of vitellogenin remains uncertain. This process differs according to the species and vitellogenesis stage or molt. Thus the present study examined the location of vitellogenin production by immunohistochemical techniques, as well as the quantification of its mRNA by Real Time PCR in female Artemesia longinaris at different stages of ovarian maturation (immature - RU, maturing EM and mature - MA). The shrimp species investigated presented a very high economic value. The study of the mechanisms of reproduction can generate data for future projects of commercial scale production contributing with the preservation of wild stocks. The molecular analyzes have confirmed the vitellogenin synthesis in the ovary and hepatopancreas of A. longinaris females during ovarian maturation. the relative expression level of vitellogenin transcripts in the ovary and the hepatopancreas during ovarian maturation show that the dynamics of vitellogenin synthesis is inversely proportional. By immunohistochemistry, it was located the endogenous synthesis of vitellogenin in follicular cells, in pre-vitellogenic oocytes and oocytes in early vitellogenesis. And the synthesis exogenous of vitellogenin was localized in cells R of hepatopancreaticos tubules. Also, given the great contribution of hepatopancreas reproductive cycle and other physiological functions of the animal, we analyzed the cellular profile of the hepatopancreatic tubule at stages of ovarian maturation. This organ has a cellular behavior that adapts to the reproductive cycle in females, in other words, the cellular cycle of hepatopancreas beyond to follow a digestive cycle is adapted to the reproductive cycle
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Silva, Rafaela Nunes da. "Dinâmica da vitelogênese durante a maturação ovariana em Artemesia longinaris /." Jaboticabal, 2014. http://hdl.handle.net/11449/116047.

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Orientador: Irene Bastos Franceschini Vicentini
Coorientador: Fernanda Antunes Alves da Costa
Banca: Rosicleire Veríssimo Silveira
Banca: Luciene Patrici Papa
Resumo: Sabe-se que em camarões peneídeos, a vitelogenina é sintetizada no ovário e hepatopâncreas, mas a contribuição relativa desses dois tecidos na síntese de vitelogenina ainda é incerta. Este processo pode diferir ainda de acordo com a espécie e estágio vitelogênico ou muda. Assim o presente estudo analisou a localização da produção de vitelogenina através de técnicas imunohistoquímicas, bem como, a quantificação do seu mRNA através do Real Time PCR em fêmeas de Artemesia longinaris em diferentes estágios de maturação ovariana (rudimentar - RU, em maturação - EM e maduro - MA). A espécie de camarão estudada apresenta altíssimo valor econômico. Assim, o estudo dos mecanismos da reprodução podem gerar dados para futuros projetos de produção em escala comercial, contribuindo com a preservação dos estoques naturais. A partir de análises moleculares confirmou-se a síntese de vitelogenina no ovário e hepatopâncreas de fêmeas de A. longinaris durante a maturação ovariana. Os níveis de expressão relativa de transcritos de vitelogenina no ovário e no hepatopâncreas durante a maturação ovariana demonstram que a dinâmica da síntese de vitelogenina é inversamente proporcional. A imunohistoquímica localizou a síntese endógena de vitelogenina nas células foliculares, nos oócitos pré-vitelogênicos e oócitos em vitelogênese inicial. E a síntese exógena de vitelogenina foi localizada nas células R dos túbulos hepatopancreáticos. Ainda, visto a grande contribuição do hepatopâncreas ao ciclo reprodutivo e às demais funções fisiológicas do animal, analisou-se o perfil celular do túbulo hepatopancreático nos estágios de maturação ovariana. Este órgão apresenta comportamento celular que se adapta ao ciclo reprodutivo em fêmeas, ou seja, o ciclo celular do hepatopâncreas além de obedecer a um ciclo digestivo é adaptado ao ciclo reprodutivo
Abstract: It is known that in penaeid shrimp the vitellogenin is synthesized into the ovary and hepatopancreas, but the relative contribution of these two tissues in the synthesis of vitellogenin remains uncertain. This process differs according to the species and vitellogenesis stage or molt. Thus the present study examined the location of vitellogenin production by immunohistochemical techniques, as well as the quantification of its mRNA by Real Time PCR in female Artemesia longinaris at different stages of ovarian maturation (immature - RU, maturing EM and mature - MA). The shrimp species investigated presented a very high economic value. The study of the mechanisms of reproduction can generate data for future projects of commercial scale production contributing with the preservation of wild stocks. The molecular analyzes have confirmed the vitellogenin synthesis in the ovary and hepatopancreas of A. longinaris females during ovarian maturation. the relative expression level of vitellogenin transcripts in the ovary and the hepatopancreas during ovarian maturation show that the dynamics of vitellogenin synthesis is inversely proportional. By immunohistochemistry, it was located the endogenous synthesis of vitellogenin in follicular cells, in pre-vitellogenic oocytes and oocytes in early vitellogenesis. And the synthesis exogenous of vitellogenin was localized in cells R of hepatopancreaticos tubules. Also, given the great contribution of hepatopancreas reproductive cycle and other physiological functions of the animal, we analyzed the cellular profile of the hepatopancreatic tubule at stages of ovarian maturation. This organ has a cellular behavior that adapts to the reproductive cycle in females, in other words, the cellular cycle of hepatopancreas beyond to follow a digestive cycle is adapted to the reproductive cycle
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Vila, Espuña Sílvia. "L'emmagatzematge intraovàric d'esperma en Helicolenus dactylopterus (Pisces: Scorpaeniformes)." Doctoral thesis, Universitat de Girona, 2010. http://hdl.handle.net/10803/7664.

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El penegal, Helicolenus dactylopterus dactylopterus (Pisces: Scorpaeniformes), és una espècie que habita profunditats d'entre els 200 i 1000 m i presenta una clara distribució batimètrica en funció de la seva talla.
Presenta fecundació interna i a l'interior de l'ovari conté estructures d'emmagatzematge que permeten emmagatzemar l'esperma durant períodes de temps considerablement llargs. Les cèl·lules sexuals masculines es mantenen viables gràcies a diverses substàncies nutritives que obtenen de la bossa citoplasmàtica i de l'epiteli criptal que delimita les estructures d'emmagatzematge. Aquest epiteli és també responsable de la seva protecció. Un cop els ous han assolit la maduresa, els espermatozoides són alliberats al lumen ovàric i es dóna la fertilització. És una espècie zigòpara: allibera òvuls fecundats que han estat retinguts al tracte reproductiu femení durant un curt període de temps i, per tant, els embrions són alliberats en estadis molt primerencs de desenvolupament. Així, el penegal presenta una estratègia reproductiva evidentment eficaç.
The bluemouth, Helicolenus dactylopterus dactylopterus (Pisces: Scorpaeniformes), is a species that inhabits the seabed at depths between 200 and 1000 m and shows a clear size-dependent bathymetric distribution.
It has internal fertilization and, inside the ovary, there are storage structures that allow it to store sperm for considerably long periods of time. These male sexual cells remain viable thanks to several nutritious substances they obtain from the cytoplasmic bag and from the cryptal epithelium that delimits the storage structures. This epithelium is also responsible for their protection. Once the eggs have reached maturity, the spermatozoa are freed in the ovarian lumen and fertilization occurs. This species is zygoparous: liberation of fertilized ova, which have been retained in the female reproductive tract during a short period of time and, therefore, the embryos are freed in very early stages of development. Thus, the bluemouth exhibits an obviously effective reproductive strategy.
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Books on the topic "Ovaries"

1

Ovarian carcinoma: Etiology, diagnosis, and treatment. 3rd ed. New York: Springer-Verlag, 1993.

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Ovarian cancer: Methods and protocols. New York: Humana Press, 2013.

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P, Bardos A., ed. Ovarian cancer: New research. New York: Nova Biomedical Books, 2005.

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H, Reznek Rodney, ed. Cancer of the ovary. Cambridge, UK: Cambridge University Press, 2007.

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Russell, Peter. Surgical pathology of the ovaries. 2nd ed. New York: Churchill Livingstone, 1997.

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Russell, Peter. Surgical pathology of the ovaries. Edinburgh: Churchill Livingstone, 1989.

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E, Tredwell Richard, ed. Ovarian cysts: Symptoms, causes, and treatment. Hauppauge, N.Y: Nova Science, 2009.

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Bristow, Robert E. Surgery for ovarian cancer: Principles and practice. 2nd ed. New York: Informa Healthcare, 2010.

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George, Coukos, Berchuck Andrew, and Ozols Robert F, eds. Ovarian cancer: State of the art and future directions in translational research. New York, NY: Springer, 2008.

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E, Bristow Robert, and Anastasia Paula J, eds. A Guide to Survivorship for Women With Ovarian Cancer. Baltimore, MD: The Johns Hopkins University Press, 2005.

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Book chapters on the topic "Ovaries"

1

Pickuth, Dirk. "Ovaries." In Essentials of Ultrasonography, 217–25. Berlin, Heidelberg: Springer Berlin Heidelberg, 1995. http://dx.doi.org/10.1007/978-3-642-79579-4_16.

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Fraser, Natalie S. "Ovaries." In Encyclopedia of Animal Cognition and Behavior, 4869–71. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-319-55065-7_1939.

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Fraser, Natalie S. "Ovaries." In Encyclopedia of Animal Cognition and Behavior, 1–2. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-47829-6_1939-1.

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Rijnberk, A. "Ovaries." In Clinical Endocrinology of Dogs and Cats, 131–56. Dordrecht: Springer Netherlands, 1996. http://dx.doi.org/10.1007/978-94-009-0105-6_7.

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Frank, J. Howard, J. Howard Frank, Michael C. Thomas, Allan A. Yousten, F. William Howard, Robin M. Giblin-davis, John B. Heppner, et al. "Panoistic Ovaries." In Encyclopedia of Entomology, 2728. Dordrecht: Springer Netherlands, 2008. http://dx.doi.org/10.1007/978-1-4020-6359-6_2746.

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Matias-Guiu, Xavier. "Endocrine Ovaries." In Endocrine Pathology:, 307–31. New York, NY: Springer New York, 2009. http://dx.doi.org/10.1007/978-1-4419-1069-1_14.

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Hillard, Paula J. Adams, and Claire Templeman. "The Ovaries." In Practical Pediatric and Adolescent Gynecology, 342–50. Oxford, UK: Blackwell Publishing Ltd., 2013. http://dx.doi.org/10.1002/9781118538555.ch48.

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Hangay, George, Susan V. Gruner, F. W. Howard, John L. Capinera, Eugene J. Gerberg, Susan E. Halbert, John B. Heppner, et al. "Meroistic Ovaries." In Encyclopedia of Entomology, 2340. Dordrecht: Springer Netherlands, 2008. http://dx.doi.org/10.1007/978-1-4020-6359-6_4555.

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Kroker, Arthur, Marilouise Kroker, and David Cook. "Panic Ovaries." In Panic Encyclopedia, 170–71. London: Macmillan Education UK, 1989. http://dx.doi.org/10.1007/978-1-349-19946-4_49.

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Uribe, Mari Carmen, Harry J. Grier, and Arlette Amalia Hernández Franyutti. "Ovaries and Eggs." In The Histology of Fishes, 126–51. Boca Raton, FL : CRC Press, [2019] | “A science publishers book.”: CRC Press, 2019. http://dx.doi.org/10.1201/9780429113581-10.

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Conference papers on the topic "Ovaries"

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Mazumdar, Darshana. "Association of organochlorine pesticides and risk of epithelial ovarian cancer: A case control study." In 16th Annual International Conference RGCON. Thieme Medical and Scientific Publishers Private Ltd., 2016. http://dx.doi.org/10.1055/s-0039-1685303.

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Background: Organochlorine pesticides (OCPs) belongs to the class of hydrocarbons characterized by its cyclic structure. Due to their persistent nature OCP gets accumulated in the food chain and cause possible adverse health effects specifically various hormone mediated disorders. Ovarian cancer is also one of the hormone dependant cancer and begins with the transformation of cells that comprises the ovaries including surface epithelial, germ cells, etc. It has been suggested that endocrine disruption, exposure to xenobiotic and subsequent oxidative stress may antedate ovarian cancer and contribute to its pathogenesis. However, no report regarding any association of OCP level with etiology of epithelial ovarian cancer is so far available among North Indian population. Methods: A total of 120 subjects were included in this case control study, consisting of 60 histological proven cases of epithelial ovarian cancer and 60 controls subjects. Quantification of OCP levels was done by Perkin Elmer Gas Chromatograph (GC) equipped with 63Ni selective Electron Capture Detector. Results: Levels of b-HCH, endosulfan I, p’p’-DDT, p’p’-DDE and heptachlor were found significantly high in cases of epithelial ovarian cancer as compared to control. A significant association was also observed between higher levels of b-HCH and heptachlor and EOC with odds ratio of 2.76 and 2.97 respectively. Conclusion: Results indicate the plausible role of OCPs with the pathogenesis of epithelial ovarian cancer among North Indian population. Moreover, it is one of the first report suggesting significant level of heptachlor among north Indian women population with epithelial ovarian cancer.
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Chernaia, A. I., O. N. Antosyuk, and E. V. Bolotnik. "EFFECT OF ETHANOL EXTRACT OF MONARDA CITRIODORA (CERV. EX LAG.) ON THE REPRODUCTIVE SYSTEM OF DROSOPHILA MELANOGASTER." In X Международная конференция молодых ученых: биоинформатиков, биотехнологов, биофизиков, вирусологов и молекулярных биологов — 2023. Novosibirsk State University, 2023. http://dx.doi.org/10.25205/978-5-4437-1526-1-145.

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During testing of the Monarda citriodora extract on the example of a model object Drosophila melanogaster, its effect on the reproductive system was found, namely, a positive effect on sexual activity and a negative effect on average individual fertility and an alteration in regulated cell death in the ovaries of females.
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Amaral, Marcello Magri, Aixia Sun, Yilin Li, Ping Wang, Zexu Jiao, and Chao Zhou. "Study of Mice Ovaries using Optical Coherence Tomography." In Latin America Optics and Photonics Conference. Washington, D.C.: Optica Publishing Group, 2022. http://dx.doi.org/10.1364/laop.2022.tu1b.5.

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We investigate the age-related follicle and oocyte morphological differences using Optical Coherence Tomography (OCT). The oocyte’s development stages were observed and discussed. OCT technique can provide a real-time imaging tool for future ovarian tissue characterization.
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Trigui, R., S. Yahiaoui, S. Zarraa, R. Abidi, K. Mahjoubi, A. Belaid, C. Nasr, et al. "P43 Dose received by ovaries during preoperative uterovaginal brachytherapy." In ESGO Annual Meeting Abstracts. BMJ Publishing Group Ltd, 2019. http://dx.doi.org/10.1136/ijgc-2019-esgo.105.

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Khurana, Anil, Paramjeet Kaur, Ashok K. Chauhan, Yashpal Verma, and Nupur Bansal. "Extra ovarian adult granulosa cell tumor of omentum: A report of a rare entity." In 16th Annual International Conference RGCON. Thieme Medical and Scientific Publishers Private Ltd., 2016. http://dx.doi.org/10.1055/s-0039-1685372.

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Aims: Extra ovarian granulosa cell tumor (GCT) is extremely rare tumor, assumed to arise from the ectopic gonadal tissue along the embryonal route of the genital ridge. A case of extra ovarian granulosa cell tumor of omentum in a 69 year old female presented here. Materials and Methods: A 69 years old postmenopausal, hypertensive female presented with complaints of pain in right lumber and iliac region of one month duration. Pain was off and on and intermittent. The patient had a history of hysterectomy 12 years ago for fibroid uterus. Results: Ultrasound examination of abdomen showed a hypoechoic lesion of size 78.1 mm x 57.3 mm in right iliac fossa with mild thickening of surrounding omentum. Another hypoechoic lesion of size 36.7 mm x 22.9 mm was seen in retroperitoneal region in supero-medial aspect of right kidney. CECT abdomen showed heterogeneously enhanced nodular lesion of size 6.6 x 6.8 cm in right lumbar region, mild thickening of surrounded omentum also seen however there was no evidence of infiltration to bowel loop seen. Uterus was not visualized. PET CT whole body revealed mildly metabolically active enlarged nodes in the bilateral level ib an ii, metabolically active large lobulated heterogeneously enhancing soft tissue density lesion in right lumbar region with non enhancing areas of necrosis. The lesion is closely abutting the anterior abdominal wall musculature antero laterally and small bowel loop medially surrounding mesenty shows increased vascularity and haziness. Colonoscopy findings were normal. Trucut biopsy of mass right lumbar region was positive for malignancy likely Round cell Sarcoma. A provisional diagnosis of retroperitoneal sarcoma of right lumbar region was made. She underwent exploratory laparotomy with excision of tumor. As per Operative findings there was approximately 8 x 7 cm, firm, omental mass present right to midline, arising from under surface of greater omentum. Ovaries were normal. Gross examination of omental mass showed nodular mass measuring 8 x 5 x 6 cm. External surface was multinodular and cut surface was grey brown to grey yellow with solid cystic areas and areas of necrosis. Microscopic examination of specimen showed Extraovarian Adult granulosa cell tumor/metastasis from occult granulose cell tumor. On IHC Vimentin, CK, SMA, Inhibin were positive, Ki67:15%, ER/PR were also positive and are negative for calretinin, thromobomodulin. Extensive necrosis was seen. After that she underwent rexploration and total omenectomy. HPE showed fat necrosis in omentum. All investigation showed no evidence of tumor in ovaries and at any other primary site then the patient finally diagnosed as having Granulosa cell tumor involving only omentum post op stage III C. Then patient was given six courses of chemotherapy with Inj Paclitaxel and Inj Carboplatin three weekly. Now patient is on regular follow up and disease free. Conclusion: Extra ovarian adult granulosa cell tumor of omentum is rare tumor. Multimodal treatment approaches including surgery, multi-agent chemotherapy may provide a survival benefit for patients.
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Bradaric, Michael J., Animesh Barua, Krishna Penumatsa, Pincas Bitterman, Jacques S. Abramowicz, Janice M. Bahr, and Judith L. Luborsky. "Abstract 1918: Lymphocyte content differs in normal ovaries and ovarian tumor stages in spontaneous ovarian cancer in the chicken." In Proceedings: AACR 101st Annual Meeting 2010‐‐ Apr 17‐21, 2010; Washington, DC. American Association for Cancer Research, 2010. http://dx.doi.org/10.1158/1538-7445.am10-1918.

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Ziyadova, Gunel, Mehmet Coskun Salman, Murat Gultekin, and Nejat Ozgul. "278 Gynaecologic and non-gynaecologic tumors metastatic to the ovaries." In ESGO SoA 2020 Conference Abstracts. BMJ Publishing Group Ltd, 2020. http://dx.doi.org/10.1136/ijgc-2020-esgo.92.

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Chitra, P., K. Srilatha, M. Sumathi, C. Ishwarya, and Mandala Jagadesh. "Automated Detection of Polycystic Ovaries using Pretrained Deep Learning Models." In 2023 Annual International Conference on Emerging Research Areas: International Conference on Intelligent Systems (AICERA/ICIS). IEEE, 2023. http://dx.doi.org/10.1109/aicera/icis59538.2023.10420280.

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Ziober-Malinowska, P., M. Bobinski, K. Barszczewska, K. Fraszczak, J. Kotarski, and R. Tarkowski. "EP1042 Evaluation of PCTAIRE2 kinase expression in ovarian cancer and ovaries and fallopian tubes with BRCA1 mutation." In ESGO Annual Meeting Abstracts. BMJ Publishing Group Ltd, 2019. http://dx.doi.org/10.1136/ijgc-2019-esgo.1085.

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Hiremath, P. S., and Jyothi R. Tegnoor. "Recognition of follicles in ultrasound images of ovaries using geometric features." In 2009 International Conference on Biomedical and Pharmaceutical Engineering (ICBPE). IEEE, 2009. http://dx.doi.org/10.1109/icbpe.2009.5384097.

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Reports on the topic "Ovaries"

1

Glintborg, Dorte, Naja Due Kolster, Pernille Ravn, and Marianne Skovsager Andersen. Prospective risk of type 2 diabetes in normal weight women with polycystic ovary syndrome. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, June 2022. http://dx.doi.org/10.37766/inplasy2022.6.0070.

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Review question / Objective: To investigate the risk for type 2 diabetes (T2D) in normal weight women with PCOS. The following PECOs (Population, Exposure, Comparator and Outcome) were included: Population: Pre- and postmenopausal women. Exposure: PCOS Comparator: Healthy control or background population. Outcome: T2D. Condition being studied: Polycystic ovary syndrome (PCOS) is a common endocrine disorder of reproductive-aged women with a prevalence of 15–20%. Polycystic ovary syndrome (PCOS) is most often defined according to the Rotterdam criteria, which include irregular ovulation, biochemical/clinical hyperandrogenism, and/or polycystic ovaries when other causes are excluded.
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Adelberg, Jeff, Halina Skorupska, Bill Rhodes, Yigal Cohen, and Rafael Perl-Treves. Interploid Hybridization of Cucumis melo and C. metuliferus. United States Department of Agriculture, December 1999. http://dx.doi.org/10.32747/1999.7580673.bard.

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The long-term motivation for this research is to transfer useful traits from a broad based gene pool of wild species into the narrow base of a cultivated crop in Cucumis. Our primary focus was to use polyploid prior to fertilization as a tool to overcome fertility barriers in the cross between C. melo and C. metuliferus. In conducting this research, we explored all combinations of tetraploid and diploid parents, in reciprocal combinations. Pollinations were made in both the field and greenhouse, using emasculated flowers, moneocious females, and open pollination by insect vectors, with morphological selection criteria. After observations of thousands of ovaries, we still have no definitive proof that this hybridization yielded viable embryos. The most promising results came from using tetraploid C. metuliferus, as the maternal parent in the interspecific hybridization, that set fruit were seeds contained small embryos that did not germinate. To obtain fruit set, it was important to rear plants in a cooler sunny greenhouse, as would be found in late winter/early spring. A second interspecific hybrid between wild and cultivated Cucumis, C. hystrix x C. sativus, yielded fertile progeny for the first time, while concomitantly working toward our primary goal. Two distinct treatments were necessary; 1) special plant husbandry was necessary to have the wild species produce fruit in cultivation, and 2) embryo rescue followed by chromosome doubling in vitro was required for fertility restoration. Backcrosses to crop species and resistance to nematodes are compelling areas for further work.
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Luborsky, Judith. Ovarian Autoantibodies Predict Ovarian Cancer. Fort Belvoir, VA: Defense Technical Information Center, November 2010. http://dx.doi.org/10.21236/ada561947.

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López-Martínez, Samuel Isaí, Jesús Gerardo Sánchez-Valadez, María Andrea Tijerina-Torres, Rodrigo Melendez-Coral, and Javier Jesús Onofre-Castillo. Ultrasonographic Diagnosis of Left-sided Ovarian Torsion in a Twin Pregnancy at 24 weeks: A Case-Report. Science Repository, November 2022. http://dx.doi.org/10.31487/j.crogr.2022.02.01.

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We describe a case report of ovarian torsion in a Korean-speaking woman with a 24-week twin pregnancy who attended a Spanish- and English-speaking institution. Ovarian torsion represents a diagnostic challenge for clinicians and radiologists because of its lack of pathognomonic symptoms and imaging findings. Ultrasonography may show unilateral ovarian enlargement without color Doppler flow and free fluid; however, clinical data should be mandatory for management decisions.
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Wang, Xinrun, Tianye Li, Xuechai Bai, Yun Zhu, and Meiliang Zhang. Therapeutic prospect on umbilical cord mesenchymal stem cells in animal model with primary ovarian insufficiency: A meta-analysis. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, May 2023. http://dx.doi.org/10.37766/inplasy2023.5.0075.

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Review question / Objective: Participants: experiment POI animal models; Interventions: human umbilical cord mesenchymal stem cells; Comparisons: POI animal models without hUCMSC therapy; Outcomes: estrous cycle situation, serum sex hormone level and ovarian follicle count; Studies: randomized controlled animal study; The aim of the review is to figure out whether hUCMSC can recover ovarian function in POI animal models. Condition being studied: Primary ovarian insufficiency (POI) is a syndrome characterized by reduced or absent ovarian function (hypogonadism) and elevated levels of gonadotropins, specifically luteinising hormone (LH) and follicle-stimulating hormone (FSH). Etiologies of POI are various. Genetic disorders, autoimmune diseases, iatrogenic injuries like chemotherapy and radiotherapy, and infectious diseases all contribute to the development of POI. Main manifestation of POI includes decreased ovarian function and infertility. Patients may suffer from menopausal symptoms, such as increased cardiovascular disease, decreased bone mineral density, vulvovaginal atrophy, psychological distress and so on. Current treatment of POI is limited. HRT mainly ameliorates symptoms while ART can achieve fertility in some patients but faces many challenges in clinical practice because it's hard to get satisfied oocytes. Stem cell therapy is proved to be efficient in recovering organ functions and hUCMSC is one of the easiest cell to obtain. So we think hUCMSC is promising in treating POI.
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Mai, Zhefen, Chunli Lu, Zixun Zhuang, and Hongxia Ma. Effectiveness and safety of Er-xian Decoction (traditional Chinese medicine) for women with Primary ovarian insufficiency. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, November 2021. http://dx.doi.org/10.37766/inplasy2021.11.0107.

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Review question / Objective: To assess the effectiveness and safety of Er-xian Decoction in the treatment of primary ovarian insufficiency. Information sources: We will search the following electronic databases, including 3 English databases (PubMed, EMBASE, Cochrane Library) and 4 Chinese databases (China national knowledge infrastructure database, Wanfang database, Sinomed Database, and VIP database). The filters were English and Chinese language. The following key words in Title/Abstract or MeSH search headings are used: “Er-xian” and “Hormone replacement therapy” or “Femoston” or “Climen” and “Primary ovarian insufficiency” or “Ovarian failure” or “Premature ovarian failure” or “POI” and “random*” or “Randomized controlled trial”. In addition, we also search the grey literature such as conference proceedings and dissertations in CNKI and Wanfang database, and relevant trials will be searched in ClinicalTrial.gov database [20] and Chinese Clinical Trial Registry for unpublished trials and protocols. References of all included studies will be hand searched for additional eligible studies.
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Kengsakul, Malika, Gatske Nieuwenhuyzen – de Boer, and Heleen van Beekhuizen. Radiological factors associated with residual disease after cytoreductive surgery for advanced ovarian cancer. INPLASY - International Platform of Registered Systematic Review and Meta-analysis Protocols, January 2023. http://dx.doi.org/10.37766/inplasy2023.1.0059.

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Review question / Objective: Which radiological factors associated with incomplete cytoreduction (gross residual disease) after cytoreductive surgery (CRS) for advanced ovarian cancer? Condition being studied: Findings of CT scan and discussion in the multidisciplinary tumor board meeting (MDO) are crucial to determine the therapeutic strategy for individual ovarian cancer patients. Preferably, patients undergo primary cytoreductive surgery (CRS) followed by adjuvant chemotherapy. However, when complete cytoreduction is not considered feasible, neoadjuvant chemotherapy followed by interval cytoreductive surgery and adjuvant chemotherapy is indicated. In patients with advanced stage epithelial ovarian cancer (EOC), maximal cytoreduction to no gross residual tumor (complete cytoreduction) is known to associated with the best overall survival.
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Engstrom, Paul F. Ovarian Cancer Prevention Program. Fort Belvoir, VA: Defense Technical Information Center, October 2000. http://dx.doi.org/10.21236/ada394778.

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Engstrom, Paul F. Ovarian Cancer Prevention Program. Fort Belvoir, VA: Defense Technical Information Center, October 2001. http://dx.doi.org/10.21236/ada406118.

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Gershenson, David M. Chemoprevention of Ovarian Cancer. Fort Belvoir, VA: Defense Technical Information Center, October 2004. http://dx.doi.org/10.21236/ada431319.

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