Dissertations / Theses on the topic 'Ovarian development'
Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles
Consult the top 50 dissertations / theses for your research on the topic 'Ovarian development.'
Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.
You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.
Browse dissertations / theses on a wide variety of disciplines and organise your bibliography correctly.
Fairs, Nicola Jane. "Steroids and ovarian development in decapod crustacea." Thesis, University of Liverpool, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.277210.
Full textUusi-Kerttula, Hanni. "Development of ovarian cancer-targeted adenoviral vectors." Thesis, Cardiff University, 2017. http://orca.cf.ac.uk/100129/.
Full textKanakkaparambil, Raji. "Methyl metabolism and ovarian follicle development in sheep." Thesis, University of Nottingham, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.478930.
Full textSefton, Elaine Marie. "Ovarian development in the edible crab, Cancer pagurus." Thesis, University of Liverpool, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.426098.
Full textWang, Qi. "Chemerin and Prohibitin in the Regulation of Ovarian Follicular Development and their Potential Involvement in Polycystic Ovarian Syndrome." Thèse, Université d'Ottawa / University of Ottawa, 2013. http://hdl.handle.net/10393/24098.
Full textLoffler, Kelly Anne. "Molecular genetics of vertebrate sex determination and ovarian development /." St. Lucia, Qld, 2003. http://www.library.uq.edu.au/pdfserve.php?image=thesisabs/absthe17476.pdf.
Full textMcRae, Thomas Geoffrey, and mikewood@deakin edu au. "Control of ovarian development in the Yabby (Cherax destructor)." Deakin University. School of Ecology and Environment, 1998. http://tux.lib.deakin.edu.au./adt-VDU/public/adt-VDU20050825.135944.
Full textLeinster, David Amdrew. "Development of an intravital microscopy model of ovarian cancer." Thesis, Queen Mary, University of London, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.515152.
Full textShuttleworth, Gail. "Porcine ovarian follicle development and the renin-angiotensin system." Thesis, University of Nottingham, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.324699.
Full textBurke, Christopher R. "Regulation of Ovarian Follicular Development with Estradiol in Cattle." The Ohio State University, 2003. http://rave.ohiolink.edu/etdc/view?acc_num=osu1054666226.
Full textTelfer, Evelyn Elizabeth. "Factors influencing follicular development in mammalian ovaries." Thesis, University of Edinburgh, 1988. http://hdl.handle.net/1842/26993.
Full textLekola, Khomotso Podile Molvia. "Improvement of cattle oocyte retrieval techniques and hormonal influence on in vitro embryonic development." Thesis, University of Limpopo, 2015. http://hdl.handle.net/10386/1546.
Full textThe objectives of this study were: 1) To determine the effect of oocyte retrieval techniques (slicing and aspiration) on the quality and quantity of cattle oocytes, 2) To evaluate the effect of different concentrations of hormones on the maturational rate of cattle oocytes selected by brilliant cresyl blue staining, 3) To evaluate fertilization rate and cleavage/embryonic development of oocytes with or without cumulus cells, and 4) To compare the effect of fresh and frozen thawed semen on the fertilization rate of cattle oocytes. In Experiment 1: oocytes were recovered from abattoir derived ovaries using slicing and aspiration. The recovered oocytes were exposed for 90 minutes to 26μM of brilliant cresyl blue (BCB) stain and classified according to the colour of their cytoplasm: BCB+ (oocytes with blue cytoplasm) and BCB- (unstained oocytes). There was no difference (P>0.05) in the quality of oocytes recovered using slicing (60.7 %) or aspiration (53.7 %) techniques. In experiment 2: The BCB selected and the non-selected immature oocytes were randomly allocated into medium 199 + 10 % fetal bovine serum (FBS) maturation media. The media was supplemented with three different concentrations of hormones as treatments (T). The T1 (0.5 μg/ml of follicle stimulating hormone (FSH), 5mg/ml of luteinizing hormone (LH) and 2 μg/ml of estradiol (E2) as the control group. Then, T2 (1 μg/ml of FSH, 6 mg/ml of LH and 2.5 μg/ml of E2) and T3 (1.5 μg/ml of FSH, 7 mg/ml of LH and 4.5 μg/ml of E2). Maturation rate of oocytes was determined by the protrusion of the first polar bodies 24 hours following in vitro maturation. Treatment 2 yielded higher (P<0.05) maturation rate for both BCB+ (65.6 %) and without BCB (60.3 %) oocytes with T1 giving lower (P<0.05) maturation rate for BCB+ (22 %) and without BCB (16 %) oocytes. However, BCB- oocytes had lower (P<0.05) polar body extrusion (3.03 %, 8.1 % and 2.2 %) for T1, T2 and T3, respectively. In Experiment 3: one group of the presumptive zygotes was denuded of cumulus cells and the other group was cultured with cumulus cells. The presumptive zygotes were in vitro cultured in SOF-BSA and changed to SOF-FBS after 48 hours. High fertilization/cleavage rate was observed in oocytes cultured with cumulus cells (29.0 %) compared to the denuded oocytes (20.0 %) for 2-4 cells stage. Day 7 blastocysts were more (P<0.05) on oocytes cultured with cumulus cells (32 %) compared to denuded oocytes (13 %). In experiment 4: The matured oocytes were fertilized using fresh and frozen thawed semen. The oocytes fertilized with frozen thawed semen obtained a better number of 2-4 cell cleavage (23 %) when compared to fresh semen (19 %). Oocytes that were fertilized with frozen thawed semen also obtained higher morula (13 %) and blastocyst (8 %) compared to fresh semen with morula (3.4 %) and blastocyst (2 %). In conclusion, immature oocytes that were exposed to BCB+ and cultured in M199 supplemented with 10 % FBS, 0.5 μg/ml of FSH, 5 mg/ml of LH and 2 μg/ml of E2 had a higher (P<0.05) number of matured oocytes (extrusion of first polar body) compared to those that were not exposed to BCB (no BCB). Oocytes that were cultured with cumulus cells yielded a higher (P<0.05) number of cleaved embryos compared to the denuded oocytes. Slicing yielded a higher (P<0.05) number of oocytes, however the quality of oocytes recovered was similar compared to those recovered by the aspiration technique (P>0.05). Oocytes fertilized with frozen thawed semen yielded higher (P<0.05) number of 2-4 cell, morula and blastocyst when compared with oocytes that were fertilized using fresh semen. Keywords: ovaries, oocytes, slicing, aspiration, COCs, BCB, polar body and cattle
Alvaro, Mercadal Béatriz. "Genetic factors involved in the development of premature ovarian insufficiency." Doctoral thesis, Universite Libre de Bruxelles, 2015. http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/216836.
Full textDoctorat en Sciences médicales (Médecine)
info:eu-repo/semantics/nonPublished
Soboloff, Jonathan. "Regulation of hen granulosa cell fate during ovarian follicular development." Thesis, National Library of Canada = Bibliothèque nationale du Canada, 1998. http://www.collectionscanada.ca/obj/s4/f2/dsk1/tape10/PQDD_0012/NQ38799.pdf.
Full textDanilovich, Natalia. "Ovarian development and function in follitropin receptor knockout (FORKO) mice." Thesis, McGill University, 2001. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=37647.
Full textTargeted disruption of FSH-R caused a gene dose related endocrine and gametogenic abnormality in female mice. The resulting FOllitropin R&barbelow;eceptor K&barbelow;nockO&barbelow;ut (FORKO) mutants were acyclic and infertile due to ovulatory defects, even with very high levels of FSH. Lack of FSH-R signaling in females caused a severe ovarian underdevelopment, producing estrogen deficiency. As a consequence, the null mutants developed obesity and skeletal abnormalities. The expression of nuclear estrogen receptor(s) alpha and beta genes and the corresponding proteins in the ovary and uterus of FORKO mice were maintained intact, as estrogen administration induced uterine growth and decreased accumulation of the adipose tissue. By 12 months of age, 92% of FORKO animals developed ovarian neoplasms of sex cord-stromal type similar to pathology observed in women. Our results showed, for the first time, that the loss of the FSH-R signaling mechanisms predisposes the ovary to molecular and structural changes causing tumor formation.
In contrast to acyclic and infertile FORKO (-/-) females, a phenotype of FORKO mice with a partial (+/-) disruption of the receptor gene exhibits irregular cyclicity and reduced fertility, undergoing early reproductive senescence. Our findings also demonstrate that the loss of a single allele of the FSH receptor gene causes a premature exhaustion of gonadal reserves accompanied by age-related changes in the hypothalamic-pituitary axis.
The study concludes that the FSH receptor signaling offers a protective mechanism, which gradually weakens upon reproductive senescence (menopause in women); therefore this knockout constitutes a unique and promising animal model for studying the physiology and molecular mechanisms of gonadal receptors and hormones.
Scott, Lucy C. "Biomarker development for gastrointestinal and ovarian cancer : a proteomic approach." Thesis, University of Glasgow, 2010. http://theses.gla.ac.uk/1644/.
Full textMuruvi, Wanzirai. "'In vitro' development of early-stage ovarian follicles in sheep." Thesis, University of Leeds, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.414245.
Full textO'Neill, H. C. "Transcriptional regulation of Foxl2 and its role in ovarian development." Thesis, University College London (University of London), 2014. http://discovery.ucl.ac.uk/1425464/.
Full textSwann, Kimberley Marie. "Effects of ovarian stimulation on oocyte development and embryo quality." Thesis, University of Nottingham, 2014. http://eprints.nottingham.ac.uk/14233/.
Full textSontakke, Sadanand Dewaji. "Identification and characterisation of microRNAs during bovine ovarian follicular development." Thesis, University of Edinburgh, 2015. http://hdl.handle.net/1842/17963.
Full textPloutarchou, Panayiota. "Effect of oocyte glycoproteins on ovarian follicle development and function." Thesis, University of Oxford, 2015. https://ora.ox.ac.uk/objects/uuid:ab1bad0c-bb83-48ec-82cc-be122c3dc02e.
Full textKoskela, S. (Sanna). "Granulosa cell anti-Müllerian hormone secretion in ovarian development and disease." Doctoral thesis, Oulun yliopisto, 2013. http://urn.fi/urn:isbn:9789526202853.
Full textTiivistelmä Naisen munasarjassa munarakkuloiden granuloosasolut erittävät anti-Müllerian hormonia (AMH), ja sen pitoisuudet seerumissa heijastavat jäljellä olevien munarakkuloiden määrää. Tässä tutkimuksessa tarkasteltiin AMH:n eritystä ja ilmentymistä munasarjan kehityksen aikana ja erilaisissa munasarjan toiminnan häiriötiloissa. Tuloksina havaittiin, että AMH:a ilmentyy sikiökaudella munasarjassa jo keskiraskaudesta eteenpäin. Syntymän jälkeen otetuissa seeruminäytteissä todettiin ohimenevä aivolisäkkeen ja munasarjan aktivaatio, joka ilmeni myöhemmin ennenaikaisesti syntyneillä tytöillä. Heillä havaittiin vähemmän kasvavia munarakkuloita ja matalammat seerumin AMH-pitoisuudet syntymän jälkeen kuin täysiaikaisilla tytöillä. Tämä kypsymättömyys johtui todennäköisesti munasarjan riittämättömästä palautejärjestelmästä aivolisäkkeeseen, mikä voi selittää korkeammat follikkelia stimuloivan hormonin (FSH) pitoisuudet ennenaikaisesti syntyneillä tytöillä. Ennenaikainen munasarjojen toiminnan hiipuminen voi johtua esim. kromosomi- tai geenivirheestä. Naisilla, joilla on virheellinen FSH-reseptori, tiedetään olevan munarakkuloita jäljellä, ja tulokset osoittivat seerumin AMH-pitoisuuksien olevan lähes normaali näillä naisilla. Myös tytöillä ja naisilla, joilla on todettu Turnerin oireyhtymän mosaikismi, AMH-pitoisuudet olivat merkittävästi korkeammat verrattuna muihin karyotyyppeihin. Täten AMH-määrityksen avulla voidaan mahdollisesti löytää ennenaikaisesta munasarjojen toiminnan hiipumisesta kärsivien joukosta ne naiset, joilla on vielä jäljellä munarakkuloita. Munasarjan granuloosasolukasvaimen diagnostiikka ja seuranta ovat haastavia kasvaimen myöhäisen uusiutumistaipumuksen ja harvinaisuuden vuoksi. Tulokset osoittivat, että seerumin AMH-määrityksen yhdistäminen tällä hetkellä käytössä olevaan inhibiini B -määritykseen voisi parantaa yksittäisten potilaiden seurantaa makroskooppisen kasvaimen toteamisen osalta. Tutkimus osoitti hormonaalisten yhdistelmäehkäisyvalmisteiden jatkuvan käytön vähentävän munasarjan aktiivisuutta merkittävästi annostelureitistä riippumatta, koska seerumin AMH-pitoisuudet laskivat samalla tavalla ehkäisypilleriä, -rengasta ja -laastaria käyttävillä naisilla. Tutkimus toi uutta tietoa AMH:n erityksestä munasarjan kehityksen aikana sekä AMH-määrityksen käytön mahdollisuuksista munarakkuloiden määrän arvioinnissa ja eri häiriötilojen tunnistamisessa
Blackwell, Lorna Evelyn. "In vitro growth and development of ovarian follicles for fertility preservation." Thesis, University of Leeds, 2014. http://etheses.whiterose.ac.uk/7435/.
Full textKarakji, Eli Gabriel. "Regulation of the rat ovarian plasminogen activator system during follicular development." Thesis, University of Ottawa (Canada), 1996. http://hdl.handle.net/10393/10314.
Full textJefferson, Wendy Noble. "Neonatal Exposure to the Phytoestrogen Genistein Alters Ovarian Differentiation and Development." NCSU, 2005. http://www.lib.ncsu.edu/theses/available/etd-09262005-095720/.
Full textCotterill, Matthew. "Gene function during the development of ovine oocytes and ovarian follicles." Thesis, University of Leeds, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.496543.
Full textWainright, Geoffrey. "Hormonal control of ovarian development in the edible crab, Cancer pagurus." Thesis, University of Liverpool, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.283064.
Full textChudasama, Dimple. "Discovery and development of liquid biomarkers for ovarian and lung cancer." Thesis, Brunel University, 2018. http://bura.brunel.ac.uk/handle/2438/16174.
Full textMcLaughlin, Marie. "Factors affecting in vitro development of bovine and human ovarian follicles." Thesis, University of Edinburgh, 2008. http://hdl.handle.net/1842/15350.
Full textMeerasahib, Mohamed Fareez. "Development and applications of monoclonal antibodies to TGFβ superfamily members involved in ovarian follicular development." Thesis, Oxford Brookes University, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.432722.
Full textHayes, Eleanor. "Reproductive physiology and age determination in females of the bowfly, Lucilia sericata (Meigen) (Diptera: Calliphoridae)." Thesis, University of Bristol, 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.265385.
Full textSmits, Stephanie. "Development of an ovarian cancer symptom awareness tool with tailored content for women at increased genetic risk of developing ovarian cancer." Thesis, Cardiff University, 2014. http://orca.cf.ac.uk/68779/.
Full textYoung, Anna-Mary. "Development of an immunocompetent model of oncolytic adenoviral gene therapy for ovarian cancer." Thesis, Queen Mary, University of London, 2012. http://qmro.qmul.ac.uk/xmlui/handle/123456789/8365.
Full textYun, Young Won. "The effects of superovulation on ovarian function and embryo development in rats." Thesis, University of British Columbia, 1989. http://hdl.handle.net/2429/29326.
Full textMedicine, Faculty of
Obstetrics and Gynaecology, Department of
Graduate
Enshaei, Amir. "Development of Artificial Intelligence systems as a prediction tool in ovarian cancer." Thesis, University of Newcastle Upon Tyne, 2012. http://hdl.handle.net/10443/1552.
Full textKuiper, Marcel. "Pre-clinical studies for development of immune gene therapy of ovarian cancer." Thesis, King's College London (University of London), 1998. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.299064.
Full textStilgenbauer, Morgan Grasselli. "Development of New Platinum-Based Anticancer Agents Targeting Ovarian Cancer Stem Cells." Kent State University / OhioLINK, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=kent1595328319619319.
Full textFerraz, Danilo Ribeiro 1986. "Atratividade de iscas de origem animal para dípteros muscóides em área de cerrado do sudeste brasileiro, com ênfase na família Calliphoridae." [s.n.], 2014. http://repositorio.unicamp.br/jspui/handle/REPOSIP/314359.
Full textDissertação (mestrado) - Universidade Estadual de Campinas, Instituto de Biologia
Made available in DSpace on 2018-08-25T23:06:38Z (GMT). No. of bitstreams: 1 Ferraz_DaniloRibeiro_M.pdf: 2070808 bytes, checksum: 257105fe3aaa84a8abe9acf46006298a (MD5) Previous issue date: 2014
Resumo: Os insetos apresentam importância do ponto de vista forense, possibilitando coletar evidências e informações essenciais à justiça. Para o aprimoramento das aplicações da entomologia forense é de extrema importância que sejam realizados estudos relacionados a fisiologia, taxonomia, ecologia, comportamento e distribuição da entomofauna decompositora. Dentre os insetos necrófagos, califorídeos (Diptera) apresentam grande destaque, pois produtos de origem animal são substratos para oviposição e fonte de proteínas e carboidratos para adultos, além de constituir recurso alimentar para larvas de algumas espécies. Os califorídeos passam por diferentes fases de desenvolvimento ovariano sendo que, nos estágios intermediários de desenvolvimento, há intensa deposição de vitelo pelas células tróficas. Assim, com fim de contribuir para um maior entendimento fisiológico e comportamental da família, o presente estudo objetiva avaliar e comparar sua riqueza, observando o padrão de atratividade exercido sobre moscas varejeiras por três diferentes substratos de origem animal (frango, peixe e roedor), bem como os estágios de desenvolvimento ovariano no qual os espécimes coletados se encontravam. Ao todo foram coletados 12.332 espécimes, dos quais 1.432 pertenciam a Calliphoridae. As iscas de moela de frango foram mais atrativas a ordem Diptera, ao passo que a família Calliphoridae foi mais atraída por iscas de roedor. Neste trabalho, 803 fêmeas foram dissecadas, sendo que grande parte destas fêmeas encontravam-se em estágio de vitelogênese completa demostrando a importância da proteína animal como substratos para oviposição
Abstract: Insects are of great forensic importance because they can serve as evidence and provide essential information to justice. In order to improve the applications of forensic entomology, it is of great important to study the biology, ecology, physiology, taxonomy, behavior and distribution of insect fauna associated to decomposing animal matter. Among the scavenger insects, the calliphorids (Diptera) are very important, because many species utilize animal tissues as source of protein and for immature development. Baits of animal origin can act as substrat for oviposition and as source of proteins and carbohydrates for the adults and for larval development feeding .Ovaries of calliphorids undergo different ovarian development phases from the pre-viteloogenic stage to mature eggs. Intermediate phases are characterized by deposition of yolk by the nurse cells. Thus, this study, aimed to contribute to the understanding of the physiological and behavioral characteristics of species of calliphorids, presenting and comparing species richness, attractiveness patterns of three different baits of animal origin these flies (chicken gizzard, fish and rat) as well as the stages of ovarian development in which the collected specimens were found. In all, 12,332 specimens were collected, of which 1,432 belonged to Calliphoridae. The rodent bait was the most attractive to this family while chicken gizzard was more attractive to Diptera as a whole. In this work, 803 females were dissected. The majority of these were in the stage of mature egg, indicating the use of the substracts for oviposition, although this pattern changed depending on the species analyzed
Mestrado
Biodiversidade Animal
Mestre em Biologia Animal
Rajareddy, Singareddy. "Studies of phosphatidylinositol 3 kinase (PI3K) signaling pathway in mammalian ovarian follicle activation and development." Doctoral thesis, Umeå : Univ, 2007. http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-1378.
Full textMukhopadhyay, Asima. "Development of a functional assay to test for homologous recombination in ovarian cancer." Thesis, University of Newcastle Upon Tyne, 2011. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.577481.
Full textSalmon, Nicholas Alan. "Oocyte regulation of granulosa cell gene expression during ovarian follicle development in mice." Thesis, University of Leeds, 2004. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.410899.
Full textJenkins, Julian Michael. "The development and influence of functional ovarian cysts during in vitro fertilisation cycles." Thesis, University of Southampton, 1992. https://eprints.soton.ac.uk/421964/.
Full textSchauer, Stephanie Nicole. "Role of luteinising hormone in ovarian follicle development and maturation in the mare." Thesis, University of Edinburgh, 2013. http://hdl.handle.net/1842/11731.
Full textBurroughs, Kevin Dale. "The role of ovarian hormones in the development and growth of uterine leiomyoma /." Digital version accessible at:, 1998. http://wwwlib.umi.com/cr/utexas/main.
Full textElvington, Elizabeth Ashcraft Savage. "Contactless Dielectrophoresis towards Drug Screening and Microdevice Development for Cell Sorting." Thesis, Virginia Tech, 2013. http://hdl.handle.net/10919/23294.
Full textSpecifically, low frequency contactless dielectrophoresis devices previously designed by Sano et al were used to extract the crossover frequency and specific membrane capacitance of early and late stage mouse ovarian surface epithelial (MOSE-E and MOSE-L) cells when untreated, treated with the anti-cancer sphingosine (So) metabolite and with a generally cancer-supporting sphingosine-1-phosphate (S1P) metabolite. The specific membrane capacitance of MOSE-L cells treated with So decreased and the normalized crossover frequency increased to levels matching MOSE-E cells.
Secondly, a new multilayer cDEP device featuring curved interdigitated electrode channels overlaying a straight sample channel for the purpose of cell sorting was designed, computationally modeled, fabricated, and tested. The goal of this design was to achieve continuous multi-stream sorting of cells, and preliminary testing demonstrated that prostate cancer PC3 cells were continuously deflected toward the top of the channel under an electric field, as predicted by the numerical model.
Master of Science
Barton, Rachael. "Isolation and characterisation of the ovarian cancer antigen CA125 and the development of gene directed enzyme prodrug therapy for the treatment of ovarian cancer." Thesis, University of Oxford, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.275193.
Full textJiménez, Sánchez Alejandro. "Characterisation of the tumour microenvironment in ovarian cancer." Thesis, University of Cambridge, 2019. https://www.repository.cam.ac.uk/handle/1810/287935.
Full textZampolla, Tiziana. "Development of new methods to assess the quality of zebrafish (Danio rerio) ovarian follicles." Thesis, University of Bedfordshire, 2009. http://hdl.handle.net/10547/134961.
Full textFlannery, Meghan Maureen. "Development of a Tissue Factor-Targeted Ultrasound Microbubble for Early Detection of Ovarian Cancer." The Ohio State University, 2020. http://rave.ohiolink.edu/etdc/view?acc_num=osu1594975031496173.
Full textSaddick, Salina Yahya. "Effect of the reproductive cycle on morphology and activity of the ovarian surface epithelium in mammals." Thesis, University of Edinburgh, 2010. http://hdl.handle.net/1842/4713.
Full text