Log in

Relevant bibliographies by topics / Ovarian development

Contents

Journal articles
Dissertations / Theses
Books
Book chapters
Conference papers
Reports

Academic literature on the topic 'Ovarian development'

Author: Grafiati

Published: 4 June 2021

Last updated: 29 January 2023

Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles

Select a source type:

Consult the lists of relevant articles, books, theses, conference reports, and other scholarly sources on the topic 'Ovarian development.'

Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.

You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.

Journal articles on the topic "Ovarian development"

1

Wang, Ningling, Ping Zhang, Xuejiang Guo, Zuomin Zhou, and Jiahao Sha. "Hnrnpk, a Protein Differentially Expressed in Immature Rat Ovarian Development, Is Required for Normal Primordial Follicle Assembly and Development." Endocrinology 152, no. 3 (March 1, 2011): 1024–35. http://dx.doi.org/10.1210/en.2010-0797.

Full text

Abstract:

The formation of ovarian follicles and subsequent development after birth are critical processes for female reproduction, and inappropriate coordination of these processes contributes to ovarian pathologies, such as premature ovarian failure and infertility. Identification and functional investigation of the factors involved in follicular assembly and the initial recruitment will be of great significance to the understanding of the female reproduction process. In this study, we examined the roles of transcription factor heterogeneous nuclear ribonucleoprotein K (Hnrnpk) in rat primordial folliculogenesis using RNA interference knockdown strategies. Reducing Hnrnpk mRNA levels via Hnrnpk small interfering RNAs to neonatal ovaries resulted in a substantial loss of naked oocytes, primordial and primary follicles. Structure disorganization of the ovary characterized by groups of oocytes arranged in nests, clusters of somatic cells not associated with any oocytes and many highly condensed oocyte nuclei was observed. Terminal deoxynucleotidyl transferase deoxyuridine triphosphate nick end labeling assay demonstrated that these abnormalities may be partially attributable to abnormal apoptosis of oocytes. Furthermore, the microarray analysis showed that 63 genes changed significantly (≥2-folds or ≤0.5-fold) between the ovaries treated with Hnrnpk small interfering RNAs and the controls, with 22 up-regulated genes and 41 down-regulated genes. These differentially expressed genes were involved in several critical biological processes in ovarian development. These results suggest that transcription factor Hnrnpk is a key regulator for primordial follicle assembly and development, which provides a new potential therapeutic target to regulate ovarian function and treat ovarian disease.

APA, Harvard, Vancouver, ISO, and other styles

2

Sofi, Fayaz A., Wasim Ahmed, Ghulam Nabi Dhobi, Showkat Ali Mufti, Rafi Ahmed Jan, Shaheen Nazir Lone, and Bashir Ahmad Shah. "A Early Development of Severe Ovarian Hyperstimulation Syndrome following Ovulation Induction." JMS SKIMS 14, no. 1 (June 11, 2011): 30–32. http://dx.doi.org/10.33883/jms.v14i1.70.

Full text

Abstract:

Ovarian Hyperstimulation is a rare but potentially fatal complication of ovarian stimulation during treatment of infertility. Worldwide the incidence of this syndrome is increasing due to liberal use of invitro fertilization for management of infertility. The syndrome is characterized by cystic ovarian enlargement and abnormal capillary permeability due to secretion of vasogenic substances by ovaries. The syndrome is classified into early and late variants with early variants usually mild to moderate in severity. We present a case of severe ovarian hyperstimulation syndrome (OHSS) developing early in a 25-year female while undergoing In-vitro fertilization (IVF). Six days after ovulation induction, the woman developed ascites, bilateral pleural effusion and acute renal failure with ultrasound abdomen revealing bilateral cystic enlargement of ovaries. JMS 2011;14(1):30-32

APA, Harvard, Vancouver, ISO, and other styles

3

Dwi Sandhiutami, Ni Made, Puspita Eka Wuyung, Wawaimuli Arozal, Melva Louisa, and Deni Rahmat. "Ovarian Cancer Animal Models for Preclinical Studies and Development of Ovarian Cancer Drugs." JURNAL ILMU KEFARMASIAN INDONESIA 17, no. 2 (October 29, 2019): 139. http://dx.doi.org/10.35814/jifi.v17i2.734.

Full text

Abstract:

Treatment for ovarian carcinoma is still far from optimal, animal models are still needed to study human epithelial ovarian cancer. Animal models of ovarian cancer are very important for understanding the pathogenesis of the disease and for testing new treatment strategies. Ovarian carcinogenesis models in mice have been modified and repaired to produce preneoplastic lesions and neoplastic ovaries that are pathogens resembling human ovarian cancer. Although spontaneous ovarian tumors in mice have been reported, some of the shortcomings of existing studies preclude their use as animal models of ovarian cancer. Because of this, many efforts have been made to develop animal models that are relevant for ovarian cancer. Experimental animal models are developed accurately to represent cellular and molecular changes associated with the initiation and development of human ovarian cancer. Accurate experimental models have significant potential in facilitating the development of better methods for early detection and treatment of ovarian cancer. Several animal models of ovarian cancer have been reported, including manipulation of various reproductive factors or exposure to carcinogens. The latest advance in ovarian cancer modeling is using genetically engineered mice.

APA, Harvard, Vancouver, ISO, and other styles

4

Lee, Hyun Ju, Janice M. Bahr, Pincas Bitterman, Sanjib Basu, Sameer Sharma, Jacques S. Abramowicz, and Animesh Barua. "Polycystic Ovarian Condition May Be a Risk Factor for Ovarian Tumor Development in the Laying Hen Model of Spontaneous Ovarian Cancer." Journal of Immunology Research 2018 (November 25, 2018): 1–13. http://dx.doi.org/10.1155/2018/2590910.

Full text

Abstract:

Chronic inflammation and long-standing oxidative stress are potential predisposing factors for developing malignancies, including ovarian cancer (OVCA). Information on the association of ovarian chronic abnormal conditions, including polycystic ovarian syndrome (PCOS), with the development of OVCA is unknown. The goal of this study was to examine if polycystic ovarian conditions are associated with OVCA development. In the exploratory study, 3–4-year-old laying hens were randomly selected and examined for the presence of polycystic ovaries with cancer (PCOC). In the prospective study, hens were monitored by ultrasound scanning to detect the incidence of a polycystic ovaries and subsequent development of OVCA. Tissues from normal ovaries and PCOC were examined for macrophage infiltration, expression of interleukin-16, and superoxide dismutase 2. The exploratory study detected spontaneous PCOC at early and late stages in hens. PCOC in hens were accompanied with influx of macrophages (17.33 ± 2.26 in PCOC at the early stage and 24.24 ± 2.5 in PCOC at the late stage in 20 mm2 areas of tissue as compared with 6.77 ± 1.58 in normal hens). Expression of interleukin-16 was more than 2.5-fold higher and superoxide dismutase 2 was approximately 3-fold higher in PCOC hens than normal hens. The prospective study showed the development of OVCA in some hens with polycystic ovarian condition (PCO). PCOC development in hens was associated with chronic inflammation in the ovary. Laying hens may represent a potential model for the study of spontaneous PCOS and its long-term risk of PCOC development.

APA, Harvard, Vancouver, ISO, and other styles

5

Segino, Miwa, Mario Ikeda, Fumiki Hirahara, and Kahei Sato. "In vitro follicular development of cryopreserved mouse ovarian tissue." Reproduction 130, no. 2 (August 2005): 187–92. http://dx.doi.org/10.1530/rep.1.00515.

Full text

Abstract:

In a previous report, we showed that follicles isolated from frozen/thawed mouse ovarian tissues reached the mature follicle stage on the 12th day of culture. However, the developmental ability was lower than that of fresh ovarian tissue. The purpose of this study was to define a culture system with some technical modification for preantral follicles isolated from frozen/thawed ovarian tissue and to confirm cell injury. Ovaries obtained from three-week-old female mice were cryopreserved by the rapid freezing method. Preantral follicles isolated from frozen/thawed ovarian tissues were cultured for 12–16 days. The follicles were then stimulated with human chorionic gonadotropin. In vitro fertilization was performed on the released cumulus–oocyte complexes (COCs). Preantral follicle viability was assessed by supravital staining using Hoechst 33258. Using this stain cell death was found in part of the granulosa cells of a follicle obtained from frozen/thawed ovarian tissue. On the 14th and 16th days of culture, the diameters of follicles isolated from frozen/thawed ovaries were larger than on the 12th day of culture. The released COCs were fertilized and developed to the blastocyst stage in 15.8% (12/76) of the oocytes taken from the fresh group, and in 0% (0/73), 2.9% (2/69) and 19.1% (22/115) of the oocytes taken from the frozen/thawed group that had been cultured for 12, 14 and 16 days respectively. The preantral follicles isolated from frozen/thawed mouse ovarian tissues developed slowly compared with the freshly prepared preantral follicles. During prolonged culture from 12 to 16 days, these follicles obtained the potential to fertilize and develop to the blastocyst stage.

APA, Harvard, Vancouver, ISO, and other styles

6

Cossigny (Rosairo), D. A., J. K. Findlay, and A. E. Drummond. "123. ACTIVIN A AND OVARIAN FOLLICLE DEVELOPMENT." Reproduction, Fertility and Development 21, no. 9 (2009): 42. http://dx.doi.org/10.1071/srb09abs123.

Full text

Abstract:

A significant developmental stage in ovarian folliculogenesis is the acquisition of gonadotropin sensitivity by ovarian follicles. Activin has previously been suggested to be involved in the responsiveness of granulosa cells to FSH (1). Therefore, the role of activin was investigated using a ‘physiological’ culture system to determine if pathways exist to transduce activin signals within the postnatal rat ovary. Organ cultures with day 4 whole ovaries were employed in order to assess the potential impact of Activin A on follicle growth and transition from the primordial through to the primary and later preantral stages of development. Ovaries were isolated and cultured for 10 days with the addition of supplemented DMEM/Hams F-12 media (2)and either FSH (100ng/ml), Activin A (50ng/ml), or a combination of the two. Media and treatments were refreshed every alternate day. At the end of the culture period, ovaries were fixed and sectioned, or placed immediately into Ultraspec for RNA extraction for future real-time PCR. Sections were used for morphological assessment and ovarian follicle counting of primordial, primary and preantral follicles. An evaluation of atresia by the detection of apoptotic cells was undertaken using terminal deoxynucleotidyl transferase (TdT) mediated dUTP-biotin nick-end labeling (TUNEL). Primary follicle numbers increased significantly (P<0.05) in the combined treatment group whereas, preantral follicle numbers increased significantly (P<0.0001) when treated with Activin A alone. This is consistent with a morphological appraisal of atresia where a decrease in atresia was found in primordial and primary follicles, supporting the primary follicle development data and Activin A treatment alone resulted in more healthy primary and preantral follicles than atretic ones. Therefore, a stimulatory role for Activin A both in the presence of FSH (primary follicle development) or alone (preantral follicle development) has resulted in more follicles making the transition from the primordial to primary stages, as well as to the later preantral stages.

APA, Harvard, Vancouver, ISO, and other styles

7

Sato, Yorino, Yuan Cheng, Kazuhiro Kawamura, Seido Takae, and Aaron J. W. Hsueh. "C-Type Natriuretic Peptide Stimulates Ovarian Follicle Development." Molecular Endocrinology 26, no. 7 (July 1, 2012): 1158–66. http://dx.doi.org/10.1210/me.2012-1027.

Full text

Abstract:

Abstract C-type natriuretic peptide (CNP) encoded by the NPPC (Natriuretic Peptide Precursor C) gene expressed in ovarian granulosa cells inhibits oocyte maturation by activating the natriuretic peptide receptor (NPR)B (NPRB) in cumulus cells. RT-PCR analyses indicated increased NPPC and NPRB expression during ovarian development and follicle growth, associated with increases in ovarian CNP peptides in mice. In cultured somatic cells from infantile ovaries and granulosa cells from prepubertal animals, treatment with CNP stimulated cGMP production. Also, treatment of cultured preantral follicles with CNP stimulated follicle growth whereas treatment of cultured ovarian explants from infantile mice with CNP, similar to FSH, increased ovarian weight gain that was associated with the development of primary and early secondary follicles to the late secondary stage. Of interest, treatment with FSH increased levels of NPPC, but not NPRB, transcripts in ovarian explants. In vivo studies further indicated that daily injections of infantile mice with CNP for 4 d promoted ovarian growth, allowing successful ovulation induction by gonadotropins. In prepubertal mice, CNP treatment alone also promoted early antral follicle growth to the preovulatory stage, leading to efficient ovulation induction by LH/human chorionic gonadotropin. Mature oocytes retrieved after CNP treatment could be fertilized in vitro and developed into blastocysts, allowing the delivery of viable offspring. Thus, CNP secreted by growing follicles is capable of stimulating preantral and antral follicle growth. In place of FSH, CNP treatment could provide an alternative therapy for female infertility.

APA, Harvard, Vancouver, ISO, and other styles

8

Chellappa, S., M. R. Câmara, and J. R. Verani. "Ovarian development in the Amazonian red discus, Symphysodon discus Heckel (Osteichthyes: Cichlidae)." Brazilian Journal of Biology 65, no. 4 (November 2005): 609–16. http://dx.doi.org/10.1590/s1519-69842005000400007.

Full text

Abstract:

The Neotropical red discus fish, Symphysodon discus, originates from the Amazonian basin and has a discoid body. Although this species is popularly used in aquaria and is exported as an ornamental fish, it has not been intensively studied. The purpose of this work was to study the morphological and histological aspects of the ovarian development in the red discus. Forty females of S. discus of varying body sizes and different stages of gonadal development were used in this study. The ovaries were weighed and examined macroscopically in order to observe the maturation stages. Histological staining of hematoxilin-eosin was used for microscopic observations of the ovaries. Macroscopic observations showed immature, maturing, mature and partially spent stages of ovarian development. Microscopic examination of the ovaries revealed five stages and five phases of ovarian development. The ovaries of the mature females showed all the different phases of oocyte development, indicating the multiple spawning habit of this species.

APA, Harvard, Vancouver, ISO, and other styles

9

Sobinoff, A. P., V. Pye, B. Nixon, S. D. Roman, and E. A. McLaughlin. "153. XENOBIOTICS; INFLUENCE ON OVARIAN FOLLICULAR DEVELOPMENT." Reproduction, Fertility and Development 21, no. 9 (2009): 71. http://dx.doi.org/10.1071/srb09abs153.

Full text

Abstract:

The mammalian female reproductive lifespan is largely defined by a finite pool of ovarian follicles established around the time of birth. It is now understood that certain synthetic chemical compounds, known as xenobiotics, can cause premature ovarian senescence through the destruction of small ovarian follicles. Although the ovotoxic effects of these chemicals are well documented, the exact molecular mechanisms behind their action are only just becoming understood. Recent evidence suggests that bioactivation of xenobiotics by Phase I detoxifying enzymes may lead to the generation of free oxygen radicals (ROS), which we suspect may perturb intracellular signalling pathways in primordial follicles. In this study we attempted to identify ovarian follicle signalling pathways activated by xenobiotic exposure using ovotoxic agents which target immature follicles. Neonatal ovaries obtained from 3/4-day old Swiss mice were exposed to either 4-Vinylcyclohexene (25µM), Methoxychlor (25µM) or Menadione (5µM) for 96hrs using our in vitro culture system. Total RNA was then collected and analysed using Affymetrix Mouse Genome 430 2.0 Arrays. Bioinformatic analysis identified between ~500–1000 genes with a two-fold significant difference in gene expression (p<0.05) for each xenobiotic compared to the control. Differentially expressed genes were analysed for pathways and molecular functions using Ingenuity Pathways Analysis (Ingenuity Systems). In agreement with the current literature, many of the genes belonged to toxic response pathways, such as; Xenobiotic metabolism (10); p53 (15) and Apoptosis (11) signalling. However, the vast majority of the differentially expressed genes belonged to canonical pathways implicated in follicular development, such as PI3K/AKT (18), Wnt/ b -catenin (21), and JAK/Stat (8) signalling. Further qPCR analysis has confirmed a substantial increase in the transcription factor Sox4 and cell cycle inhibitor Cdkn2a in 4-Vinylcyclohexene and Menadione treated ovaries respectively. These results suggest that xenobiotics which target primordial follicles may exert part of their ovotoxic effects by perturbing signalling pathways involved in follicular activation and development.

APA, Harvard, Vancouver, ISO, and other styles

10

Prokopuk, Lexie, Ellen G. Jarred, Rheannon O. Blücher, Eileen A. McLaughlin, Jessica M. Stringer, and Patrick S. Western. "An essential role for Polycomb Repressive Complex 2 in the mouse ovary." Reproduction 163, no. 3 (March 1, 2022): 167–82. http://dx.doi.org/10.1530/rep-21-0361.

Full text

Abstract:

Polycomb repressive complex 2 (PRC2) catalyses the repressive epigenetic modification of histone 3 lysine 27 tri-methylation (H3K27me3) and functions as a key epigenetic regulator during embryonic development. PRC2 is known to regulate the development of a range of tissues by transcriptional silencing of genes that control cell differentiation, but its roles in female germline and ovarian development remain unknown. Using a mouse model with hypomorphic embryonic ectoderm development (EED) function that reduced H3K27me3 in somatic and germ cells, we found that PRC2 was required for survival, with more than 95% of female animals dying before birth. Although surviving adult EED hypomorphic females appeared morphologically similar to controls and were fertile, Eedhypo/hypo adult ovaries were abnormal, with altered morphology characterised by abnormal follicles. Early Eedhypo/hypo and control fetal ovaries were morphologically similar, and germ cells entered meiosis normally. Immunofluorescent analyses of somatic and germline markers indicated that ovarian development in Eedhypo/hypo ovaries was similar to heterozygous and WT controls. However, TUNEL analyses revealed higher rates of apoptosis in the ovarian surface epithelium, and transcriptional analyses revealed changes in genes regulating epithelial and steroidogenic cell differentiation, possibly foreshadowing the defects observed in adult ovaries of hypomorphic females. While it was possible to analyse early-mid fetal ovarian development, postnatal stages were inaccessible due to the high level of lethality during late fetal stages. Despite this limitation, the data we were able to obtain reveal a novel role for EED in the ovary that is likely to alter ovarian development and ovarian function in adult animals.

APA, Harvard, Vancouver, ISO, and other styles

More sources

Dissertations / Theses on the topic "Ovarian development"

1

Fairs, Nicola Jane. "Steroids and ovarian development in decapod crustacea." Thesis, University of Liverpool, 1989. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.277210.

Full text

APA, Harvard, Vancouver, ISO, and other styles

2

Uusi-Kerttula, Hanni. "Development of ovarian cancer-targeted adenoviral vectors." Thesis, Cardiff University, 2017. http://orca.cf.ac.uk/100129/.

Full text

Abstract:

Ovarian cancer is the deadliest gynaecological cancer, with less than half of patients surviving five years from diagnosis. The asymptomatic nature of the early disease commonly results in diagnosis at an advanced stage where peritoneal metastases are prevalent, and the disease rapidly develops resistance to platinum-based agents. Innovative treatments are needed to combat this untreatable disease that has a poor prognosis. Adenoviruses (Ad) are versatile gene therapy vehicles that have been studied for six decades. Their wider clinical use has been limited by poor tumour-specificity, pre-existing immunity, and toxicity-inducing off-target delivery. We have generated an Ad5.3D.A20 vector that is re-targeted to an epithelial cancer-specific marker, αvβ6 integrin, and fully de-targeted from native interactions ‒ αvβ3/5 integrins, coxsackie and adenovirus receptor (CAR), and human coagulation factor 10 (FX). Ad5.3D.A20 selectively transduced αvβ6+ epithelial ovarian cancer (EOC) cells in vitro and clinical ovarian ascites-derived EOC cells ex vivo, including in the presence of neutralising anti-Ad antibodies. In vivo, Ad5.3D.A20 exhibited significantly reduced off-target accumulation and transduction of the liver, spleen and lungs, relative to Ad5. Efficacy studies are underway to investigate its oncolytic potential. Furthermore, we explored the potential use of alternative serotypes from the rare seroprevalence subgroup D. A novel Ad10 vector showed improved resistance from neutralisation and lack of FX binding. Chimaeric Ad5 vectors pseudotyped with Ad10, -15, -24, -29, -48 or -53 fiber had reduced interactions with CAR, but no binding to CD46. Our strategy for translation initially is via intraperitoneal delivery of oncolytic vectors, bypassingmany of the barriers presented by systemic delivery, but enabling transduction of disseminated metastases. These exquisitely tumour-targeted vectors may be further modulated to carry therapeutic moieties to complement their direct cell-killing activity via the stimulation of anti-cancer immunity. The generated tropism-modified vectors have significant therapeutic potential for a wide range of immuno-oncolytic applications.

APA, Harvard, Vancouver, ISO, and other styles

3

Kanakkaparambil, Raji. "Methyl metabolism and ovarian follicle development in sheep." Thesis, University of Nottingham, 2008. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.478930.

Full text

APA, Harvard, Vancouver, ISO, and other styles

4

Sefton, Elaine Marie. "Ovarian development in the edible crab, Cancer pagurus." Thesis, University of Liverpool, 2006. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.426098.

Full text

APA, Harvard, Vancouver, ISO, and other styles

5

Wang, Qi. "Chemerin and Prohibitin in the Regulation of Ovarian Follicular Development and their Potential Involvement in Polycystic Ovarian Syndrome." Thèse, Université d'Ottawa / University of Ottawa, 2013. http://hdl.handle.net/10393/24098.

Full text

Abstract:

Follicular growth and maturation are tightly regulated processes, which involve the participation of endocrine, autocrineparacrine factors and intracellular molecules. Due to the numerous research efforts, a large number of regulators and their mechanisms of regulation of follicular growth and differentiation have been established. Although the abnormal expression and activities of some of these regulators are believed to be associated with ovarian dysfunction diseases, such as polycystic ovarian syndrome (PCOS), the etiology and pathogenesis of this syndrome are not completely understood. In this thesis, we have identified two novel regulators of follicular growth and differentiation and examined the cellular and molecular mechanisms that contribute to the folliculogenesis. We present here that chemerin reduces FSH-induced steroidogenic enzyme expression and steroid hormone production in follicles and granulosa cells. Prohibitin expression is upregulated by chemerin and knockdown of prohibitin attenuates the suppressive role of chemerin on steroidogenesis, an action regulated by Akt. Using an androgenized rodent model, we also present the dysregulation of chemerin and prohibitin and their association with dysregulated follicular steroidogenesis. Our data and preliminary clinical studies demonstrate the potential involvement of chemerin and prohibitin in the etiology of PCOS. These studies significantly improve the knowledge of ovarian functions and the pathophysiology of PCOS, and provide important clues for the development of novel diagnosis biomarkers and new treatment strategies for this complex syndrome.

APA, Harvard, Vancouver, ISO, and other styles

6

Loffler, Kelly Anne. "Molecular genetics of vertebrate sex determination and ovarian development /." St. Lucia, Qld, 2003. http://www.library.uq.edu.au/pdfserve.php?image=thesisabs/absthe17476.pdf.

Full text

APA, Harvard, Vancouver, ISO, and other styles

7

McRae, Thomas Geoffrey, and mikewood@deakin edu au. "Control of ovarian development in the Yabby (Cherax destructor)." Deakin University. School of Ecology and Environment, 1998. http://tux.lib.deakin.edu.au./adt-VDU/public/adt-VDU20050825.135944.

Full text

Abstract:

A study under controlled conditions of ovarian development and rematuration in the yabby (Cherax destructot) was undertaken. The purpose of the study was to improve fundamental understanding of the reproductive biology of the species and provide a basis for application to hatchery management in culture. A review was made of the current status of yabby culture in Australia and the present understanding of reproductive biology of decapod Crustacea. The review emphasised factors controlling several aspects of ovarian development, in particular the processes of vitellogenesis. The subsequent study was designed within the context of current hatchery practice and was based on existing knowledge of decapod reproduction, The sexual differentiation of the yabby after hatching was investigated by serial histological sections, and experiments were carried out to investigate the possibility of sex reversal of males. Most of this Investigation was concerned with removing the influence of the androgenic gland in directing male development, with the intent of observing the development of the elementary gonadal tissue into ovary. It was found that in contrast to other crustacean species, the sex of the yabby becomes fixed before the development of external secondary sexual characteristics, and before the androgenic gland can be discerned. Ovarian tissue developed in females at less than 8 weeks after hatching. A preliminary examination was undertaken for feminising parasites in gonadal tissue of a hermaphrodite yabby. Investigation of the ovary after spawning demonstrated that whilst the female was held under constant conditions of temperature and photoperiod, little rematuration occurred. Except for generation of previtellogenic oocytes during the first two days, the gonaciosomatic index remained low for up to 5 months after spawning. If the temperature of the female was reduced to 10°C and maintained constant, the previtellogenic oocytes were partially resorbed over a three week period. Rematuration then commenced, albeit at a low rate because of the reduced temperature, A method for standardising gonadosomatic indices was developed which took into account differences in hepatopancreatic nutrient reserves of individuals and loss of one or more appendages. This part of the study also considered constraints to rematuration and developed a method of accounting for differences in the ability of females to remature after spawning. Experiments were carried out to investigate the effect of crowding and temperature manipulation on initiating ovarian rematuration and to determine the rate of rematuration at 22°C once initiated. The duration of low temperature had no effect on rematuration; an overnight cooling was sufficient to initiate the process, Rematuration to the end of stage 2 vltellogenesis was substantially complete within 10 days. Crowding of females suppressed rematuration, but less than ideal water quality was not found to have any effect. The presence of a male initiated rematuration at a similar rate, but also led to stage 3 vitetlogenesis and spawning. A study was made of the pheromonal influence of the male through water borne factors without success. Rematuration could not be induced in ovigerous females. The literature review indicated that ovarian rematuration was under the control of an ovary stimulating hormone produced by the thoracic nerve ganglia. Attempts were therefore made to stimulate ovarian rematuration by incorporating the thoracic nerve into the diet of females. Attempts were also made to induce the release of ovary stimulating hormone from the thoracic nerve with 5-hydroxytryptamine, and also with octopamine. No effects were found, but a significant difference between the neurophysiology of the yabby and northern hemisphere crayfish was observed, and the implications of this finding are discussed. The study did not produce any conclusive evidence of an ovary stimulating hormone for the yabby. A model of ovarian rematuration which collects the findings of the experimental investigations was developed, and was used to suggest a hatchery broodstock management protocol. This model differs from existing models in that rematuration triggers and nutritional status are considered.

APA, Harvard, Vancouver, ISO, and other styles

8

Leinster, David Amdrew. "Development of an intravital microscopy model of ovarian cancer." Thesis, Queen Mary, University of London, 2009. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.515152.

Full text

APA, Harvard, Vancouver, ISO, and other styles

9

Shuttleworth, Gail. "Porcine ovarian follicle development and the renin-angiotensin system." Thesis, University of Nottingham, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.324699.

Full text

APA, Harvard, Vancouver, ISO, and other styles

10

Burke, Christopher R. "Regulation of Ovarian Follicular Development with Estradiol in Cattle." The Ohio State University, 2003. http://rave.ohiolink.edu/etdc/view?acc_num=osu1054666226.

Full text

APA, Harvard, Vancouver, ISO, and other styles

More sources

Books on the topic "Ovarian development"

1

National Institutes of Health Consensus Development Conference on Ovarian Cancer (1994 National Institutes of Health). NIH Consensus Development Conference on Ovarian Cancer: Screening, treatment, and followup : NIH Consensus Development Conference, April 5-7, 1994 ... National Institutes of Health, Bethesda, Maryland. Bethesda, Md: National Institutes of Health, 1994.

Find full text

APA, Harvard, Vancouver, ISO, and other styles

2

Doshi, Rajeev. Development of gene based immunotherapy for ovarian cancer. Birmingham: University of Birmingham, 1998.

Find full text

APA, Harvard, Vancouver, ISO, and other styles

3

Health), NIH Consensus Development Conference on Ovarian Cancer (1994 National Institutes of. NIH Consensus Development Conference on Ovarian Cancer: Screening, treatment, and followup : [program and abstracts]. Bethesda, Md: National Institutes of Health, 1994.

Find full text

APA, Harvard, Vancouver, ISO, and other styles

4

Makabe, Sayoko. Atlas of human female reproductive function: Ovarian development to early embryogenesis after in vitro fertilization. London: Taylor & Francis, 2006.

Find full text

APA, Harvard, Vancouver, ISO, and other styles

5

Salinas, Josie. A pictorial guide on the ovarian development of the fertile and sterile Mexican fruitfly, Anastrepha ludens. Mission, TX: USDA-APHIS-PPQ, Mission Plant Protection Center, 1999.

Find full text

APA, Harvard, Vancouver, ISO, and other styles

6

Galvin, James A. Ovarian follicular development following oestrus syncronization programmes at different stages of the oestrous cycle in lactating dairy cows. Dublin: University College Dublin, 1995.

Find full text

APA, Harvard, Vancouver, ISO, and other styles

7

S, Tuan Rocky, and Lo Cecilia W, eds. Developmental biology protocols. Totowa, N.J: Humana Press, 2000.

Find full text

APA, Harvard, Vancouver, ISO, and other styles

8

World Congress of Gynecological Endocrinology (4th 1995 Madonna di Campiglio, Italy). Recent developments in gynecology and obstetrics: Selected papers presented at the 4th World Congress of Gynecological Endocrinology organized by the International Society of Gynecological Endocrinology joint with the 2nd Congress of the European Society for Gynecologic and Obstetric Investigation, Madonna di Campiglio, Italy, February 1995. New York: Parthenon Pub. Group, 1996.

Find full text

APA, Harvard, Vancouver, ISO, and other styles

9

Schoot. Exogenous Fsh and Development of Human Ovarian Follicles. Parthenon Pub Group, 1995.

Find full text

APA, Harvard, Vancouver, ISO, and other styles

10

Lavoué, Vincent, Patrick Legembre, Jean Levêque, Fabrice Foucher, Sébastien Henno, and Florian Cabillic. Ovarian Cancer Immunity. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780190248208.003.0003.

Full text

Abstract:

Epithelial ovarian cancer (EOC) is a significant cause of cancer-related mortality in women, and there has been no substantial decrease in the death rates due to EOC in the past three decades. Thus, basic knowledge regarding ovarian tumor cell biology is urgently needed to allow the development of innovative treatments for EOC. Traditionally, EOC has not been considered an immunogenic tumor, but there is evidence of an immune response to EOC in patients. Clinical data demonstrate that an anti-tumor immune response and immune evasion mechanisms are correlated with a better and lower survival, respectively, providing evidence for the immunoediting hypothesis in EOC. This chapter focuses on the immune response and immune suppression in EOC.

APA, Harvard, Vancouver, ISO, and other styles

More sources

Book chapters on the topic "Ovarian development"

1

Mori, Takahide. "Regulatory Principles of Follicular Development." In Ovarian Stimulation Protocols, 1–16. New Delhi: Springer India, 2016. http://dx.doi.org/10.1007/978-81-322-1121-1_1.

Full text

APA, Harvard, Vancouver, ISO, and other styles

2

Fauser, Bart C. J. M., Thierry D. Pache, and Dick C. Schoot. "Dynamics of Human Follicle Development." In Ovarian Cell Interactions, 134–47. New York, NY: Springer New York, 1993. http://dx.doi.org/10.1007/978-1-4613-8336-9_11.

Full text

APA, Harvard, Vancouver, ISO, and other styles

3

Takae, Seido, and Nao Suzuki. "Ovarian Endocrinology." In Development of In Vitro Maturation for Human Oocytes, 3–35. Cham: Springer International Publishing, 2017. http://dx.doi.org/10.1007/978-3-319-53454-1_1.

Full text

APA, Harvard, Vancouver, ISO, and other styles

4

Ojeda, Sergio R., Gregory A. Dissen, Sasha Malamed, and Anne N. Hirshfield. "A Role for Neurotrophic Factors in Ovarian Development." In Ovarian Cell Interactions, 181–202. New York, NY: Springer New York, 1993. http://dx.doi.org/10.1007/978-1-4613-8336-9_14.

Full text

APA, Harvard, Vancouver, ISO, and other styles

5

Zweizig, S., J. Zheng, M. Wan, T. M. Kim, M. Velicescu, J. Gosewehr, and L. Dubeau. "New insights into the genetics of human ovarian epithelial tumor development." In Ovarian Cancer 3, 61–73. Boston, MA: Springer US, 1995. http://dx.doi.org/10.1007/978-1-4757-0136-4_7.

Full text

APA, Harvard, Vancouver, ISO, and other styles

6

Farookhi, Riaz, and Orest W. Blaschuk. "Cadherins and Ovarian Follicular Development." In Signaling Mechanisms and Gene Expression in the Ovary, 254–60. New York, NY: Springer New York, 1991. http://dx.doi.org/10.1007/978-1-4612-3200-1_25.

Full text

APA, Harvard, Vancouver, ISO, and other styles

7

Tewari, Krishnansu S. "Historical Development of Cytoreductive Surgery for Ovarian Cancer and Scientific Update." In Surgery for Ovarian Cancer, 1–8. 4th ed. Boca Raton: CRC Press, 2022. http://dx.doi.org/10.1201/9780429054433-1.

Full text

APA, Harvard, Vancouver, ISO, and other styles

8

Niikura, Yuichi, and Joshua Johnson. "Ovarian Follicle Development and Fertility Preservation." In Fertility Preservation in Females, 33–51. New York, NY: Springer New York, 2012. http://dx.doi.org/10.1007/978-1-4614-5617-9_3.

Full text

APA, Harvard, Vancouver, ISO, and other styles

9

Niikura, Yuichi, and Joshua Johnson. "Ovarian Follicle Development and Fertility Preservation." In Fertility Preservation, 29–43. New York, NY: Springer New York, 2011. http://dx.doi.org/10.1007/978-1-4419-1783-6_3.

Full text

APA, Harvard, Vancouver, ISO, and other styles

10

McLaughlin, Eileen A., and Alexander P. Sobinoff. "Contraception Targets in Mammalian Ovarian Development." In Handbook of Experimental Pharmacology, 45–66. Berlin, Heidelberg: Springer Berlin Heidelberg, 2010. http://dx.doi.org/10.1007/978-3-642-02062-9_4.

Full text

APA, Harvard, Vancouver, ISO, and other styles

Conference papers on the topic "Ovarian development"

1

Lu, Xinguo, and Jibo Lu. "Identifying candidate driver genes by integrative ovarian cancer genomics data." In GREEN ENERGY AND SUSTAINABLE DEVELOPMENT I: Proceedings of the International Conference on Green Energy and Sustainable Development (GESD 2017). Author(s), 2017. http://dx.doi.org/10.1063/1.4992920.

Full text

APA, Harvard, Vancouver, ISO, and other styles

2

Rahman, Md Akizur, Ravie Chandren Muniyandi, Kh Tohidul Islam, and Md Mokhlesur Rahman. "Ovarian Cancer Classification Accuracy Analysis Using 15-Neuron Artificial Neural Networks Model." In 2019 IEEE Student Conference on Research and Development (SCOReD). IEEE, 2019. http://dx.doi.org/10.1109/scored.2019.8896332.

Full text

APA, Harvard, Vancouver, ISO, and other styles

3

Choi, Pui–Wah, Brooke E. Howitt, Christopher P. Crum, Ross S. Berkowitz, and Shu–Wing Ng. "Abstract MIP-052: THE ROLES OF CD24 IN OVARIAN CANCER DEVELOPMENT." In Abstracts: 11th Biennial Ovarian Cancer Research Symposium; September 12-13, 2016; Seattle, WA. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1557-3265.ovcasymp16-mip-052.

Full text

APA, Harvard, Vancouver, ISO, and other styles

4

Scholler, Nathalie, Paul Stein, Khushboo Sharma, Claire Repellin, Kalika Kamat, Travis Harrison, Robert H. Shoemarker, Shizuko Sei, and Lidia Sambucetti. "Abstract A041: Preclinical development of a preventive vaccine against ovarian cancer." In Abstracts: Second CRI-CIMT-EATI-AACR International Cancer Immunotherapy Conference: Translating Science into Survival; September 25-28, 2016; New York, NY. American Association for Cancer Research, 2016. http://dx.doi.org/10.1158/2326-6066.imm2016-a041.

Full text

APA, Harvard, Vancouver, ISO, and other styles

5

Sarty, Gordon E., Milan Sonka, Weidong Liang, and Roger A. Pierson. "Development of an automatic follicle isolation tool for ovarian ultrasonographic images." In Medical Imaging 1997, edited by Kenneth M. Hanson. SPIE, 1997. http://dx.doi.org/10.1117/12.274170.

Full text

APA, Harvard, Vancouver, ISO, and other styles

6

Xia, Zhouchunyang, Dawn Cochrane, Michael S. Anglesio, Tayyebeh M. Nazeran, Janine Senz, Amy Lum, Ali Bashashati, Yi Kan Wang, Sohrab P. Shah, and David Huntsman. "Abstract DPOC-014: BEYOND CODING MUTATIONS: USING RETROTRANSPOSONS TO PREDICT OVARIAN CANCER DEVELOPMENT." In Abstracts: 11th Biennial Ovarian Cancer Research Symposium; September 12-13, 2016; Seattle, WA. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1557-3265.ovcasymp16-dpoc-014.

Full text

APA, Harvard, Vancouver, ISO, and other styles

7

Hwang, Larn, Chao Hsiao, Kouros Motamed, and Vuong Trieu. "Abstract 3481: Development of personalized paclitaxel therapy (IG-001) for ovarian cancer." In Proceedings: AACR 104th Annual Meeting 2013; Apr 6-10, 2013; Washington, DC. American Association for Cancer Research, 2013. http://dx.doi.org/10.1158/1538-7445.am2013-3481.

Full text

APA, Harvard, Vancouver, ISO, and other styles

8

Want, Muzamil Y., Takemasa Tsuji, Richard Koya, and Sebastiano Battaglia. "Abstract 5674: Cancer immunogenomics for the development of personalized ovarian cancer vaccine." In Proceedings: AACR Annual Meeting 2017; April 1-5, 2017; Washington, DC. American Association for Cancer Research, 2017. http://dx.doi.org/10.1158/1538-7445.am2017-5674.

Full text

APA, Harvard, Vancouver, ISO, and other styles

9

Veena, P. "Single centre experience of ovarian germ cell tumours over 8 years." In 16th Annual International Conference RGCON. Thieme Medical and Scientific Publishers Private Ltd., 2016. http://dx.doi.org/10.1055/s-0039-1685316.

Full text

Abstract:

Introduction: Germ cell tumours comprise approximately 15-20% of all ovarian tumours. Two third of ovarian tumours in first two decades of life are germ cell tumours. Majority of ovarian germ cell tumours are benign teratomas. The malignant germ cell tumours are usually solid and arise from totipotent germ cells. Over the past 3 decades the clinical outcome of women with ovarian germ cell tumours (OGCT) have significantly improved mainly due to development of more effective chemotherapy regimens. Objective: To study the clinic pathological features, treatment and survival of women with ovarian germ cell tumours. Methods: This is a retrospective descriptive study taken from the case files of patients with histo-pathologically proven ovarian germ cell tumours who were treated in JIPMER over 8 years from 2007 to 2014. Results: There were totally 63 patients with ovarian germ cell tumours over 8 years who were treated in JIPMER. The age at presentation varies from 12 years to 65 years with a median age of 26.5 years. Three were pre pubertal and 1 was post-menopausal. Twenty two women (34%) were unmarried and 5 were pregnant at the time of presentation. Forty eight (76%) of them did not have any menstrual abnormalities. Pain abdomen (55%) was the most common presentation. Ten of them presented with acute abdomen of which 8 were torsion, 1 was ruptured dermoid and 1 was infected dermoid. Another 6 patients had torsion which was diagnosed only during surgery. Majority (68%) were benign tumours (dermoid) and among malignant tumours, there were 6 dysgerminomas, 5 immature teratomas, 5 mixed germ cell tumours and 4 yolk sac tumours. Almost half (22 out of 43) of women with benign tumours were <25 years whereas 3/4th (14 out of 20) of women with malignant germ cell tumours were <25 years. The most common tumour marker which was elevated was alpha feto protein (8) followed by LDH (5). Fertility sparing surgery (salpingo-ovariotomy) was commonly performed which was 95% (41/43) in benign tumours and 60% (8/20) in malignant tumours. Contra lateral ovary was biopsied in only 5 patients with suspected involvement (negative on final HPR). Out of 20 women with malignant ovarian tumours 7 were in advanced stage (Stage III). Majority of them recovered well from surgery, only 12% had post-operative febrile morbidity and one patient had subclavian vein thrombosis on post op D9 which required anticoagulants. 7 of 20 women received chemotherapy (BEP) for 4 cycles. No serious side effects of chemotherapy were noted in these women. 3 out of 20 women with malignant germ cell tumour were lost to follow up. No recurrences have been found in rest of the women and there are no deaths till last follow up. Conclusion: Advances in the field of medicine like effective chemotherapy regimens, improved imaging, precise surgical staging and fertility sparing surgical procedures enable women not only to preserve the reproductive function but also to improve their quality of life.

APA, Harvard, Vancouver, ISO, and other styles

10

Emmanuel, Adegbite, Joseph O. Sanya, and Olujide O. Olubiyi. "Abstract NT-086: PRELIMINARY IDENTIFICATION OF LACTATE DEHYDROGENASE INHIBITORS TOWARDS ANTICANCER DRUG DEVELOPMENT." In Abstracts: 12th Biennial Ovarian Cancer Research Symposium; September 13-15, 2018; Seattle, Washington. American Association for Cancer Research, 2019. http://dx.doi.org/10.1158/1557-3265.ovcasymp18-nt-086.

Full text

APA, Harvard, Vancouver, ISO, and other styles

Reports on the topic "Ovarian development"

1

Markland, Francis S., and Stephen D. Swenson. Development of a Multifaceted Ovarian Cancer Imaging Agent. Fort Belvoir, VA: Defense Technical Information Center, April 2010. http://dx.doi.org/10.21236/ada551849.

Full text

APA, Harvard, Vancouver, ISO, and other styles

2

Markland, Francis S. Development of a Multifaceted Ovarian Cancer Therapeutic and Imaging Agent. Fort Belvoir, VA: Defense Technical Information Center, April 2008. http://dx.doi.org/10.21236/ada485607.

Full text

APA, Harvard, Vancouver, ISO, and other styles

3

Meruelo, Daniel. Development and Novel Uses of Antibodies in Epithelial Ovarian Cancer. Fort Belvoir, VA: Defense Technical Information Center, September 2004. http://dx.doi.org/10.21236/ada431645.

Full text

APA, Harvard, Vancouver, ISO, and other styles

4

Markland, Francis S. Development of a Multifaceted Ovarian Cancer Therapeutic and Imaging Agent. Fort Belvoir, VA: Defense Technical Information Center, April 2009. http://dx.doi.org/10.21236/ada508223.

Full text

APA, Harvard, Vancouver, ISO, and other styles

5

Markland, Francis S. Development of a Multifaceted Ovarian Cancer Therapeutic and Imaging Agent. Fort Belvoir, VA: Defense Technical Information Center, April 2011. http://dx.doi.org/10.21236/ada548638.

Full text

APA, Harvard, Vancouver, ISO, and other styles

6

Curtin, John P. Development and Novel Uses of Antibodies in Epithelial Ovarian Cancer. Fort Belvoir, VA: Defense Technical Information Center, August 2004. http://dx.doi.org/10.21236/ada469576.

Full text

APA, Harvard, Vancouver, ISO, and other styles

7

Tworoger, Shelley. Development of the Ovarian Cancer Cohort Consortium: Risk Factor Associations by Heterogeneity of Disease. Fort Belvoir, VA: Defense Technical Information Center, October 2014. http://dx.doi.org/10.21236/ada612705.

Full text

APA, Harvard, Vancouver, ISO, and other styles

8

Tworoger, Shelley. Development of the Ovarian Cancer Cohort Consortium: Risk Factor Associations by Heterogeneity of Disease. Fort Belvoir, VA: Defense Technical Information Center, October 2013. http://dx.doi.org/10.21236/ada597887.

Full text

APA, Harvard, Vancouver, ISO, and other styles

9

Gong, Jianlin. Development of a Novel Vaccine with Fusions of Dendritic and Ovarian Cancer Cells from Patients. Fort Belvoir, VA: Defense Technical Information Center, August 2001. http://dx.doi.org/10.21236/ada404671.

Full text

APA, Harvard, Vancouver, ISO, and other styles

10

Gong, Jianlin. Development of a Novel Vaccine with Fusions of Dendritic and Ovarian Cancer Cells from Patients. Fort Belvoir, VA: Defense Technical Information Center, August 2003. http://dx.doi.org/10.21236/ada418726.

Full text

APA, Harvard, Vancouver, ISO, and other styles

We offer discounts on all premium plans for authors whose works are included in thematic literature selections. Contact us to get a unique promo code!