Academic literature on the topic 'Outer hair cells'

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Journal articles on the topic "Outer hair cells"

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Ashmore, Jonathan. "Outer Hair Cells and Electromotility." Cold Spring Harbor Perspectives in Medicine 9, no. 7 (2018): a033522. http://dx.doi.org/10.1101/cshperspect.a033522.

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Ashmore, Jonathan. "Cochlear Outer Hair Cell Motility." Physiological Reviews 88, no. 1 (2008): 173–210. http://dx.doi.org/10.1152/physrev.00044.2006.

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Normal hearing depends on sound amplification within the mammalian cochlea. The amplification, without which the auditory system is effectively deaf, can be traced to the correct functioning of a group of motile sensory hair cells, the outer hair cells of the cochlea. Acting like motor cells, outer hair cells produce forces that are driven by graded changes in membrane potential. The forces depend on the presence of a motor protein in the lateral membrane of the cells. This protein, known as prestin, is a member of a transporter superfamily SLC26. The functional and structural properties of pr
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Gummer, Anthony W., Jens Meyer, Gerhard Frank, Marc P. Scherer, and Serena Preyer. "Mechanical Transduction in Outer Hair Cells." Audiology and Neurotology 7, no. 1 (2002): 13–16. http://dx.doi.org/10.1159/000046856.

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Zenner, Hans Peter. "Motile responses in outer hair cells." Hearing Research 22, no. 1-3 (1986): 83–90. http://dx.doi.org/10.1016/0378-5955(86)90082-1.

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Prieto, J., J. A. Merchán, P. Gil-Loyzaga, and J. Rueda. "Subsurface material in outer hair cells." Hearing Research 21, no. 3 (1986): 277–80. http://dx.doi.org/10.1016/0378-5955(86)90225-x.

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Stauffer, Eric A., and Jeffrey R. Holt. "Sensory Transduction and Adaptation in Inner and Outer Hair Cells of the Mouse Auditory System." Journal of Neurophysiology 98, no. 6 (2007): 3360–69. http://dx.doi.org/10.1152/jn.00914.2007.

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Auditory function in the mammalian inner ear is optimized by collaboration of two classes of sensory cells known as inner and outer hair cells. Outer hair cells amplify and tune sound stimuli that are transduced and transmitted by inner hair cells. Although they subserve distinct functions, they share a number of common properties. Here we compare the properties of mechanotransduction and adaptation recorded from inner and outer hair cells of the postnatal mouse cochlea. Rapid outer hair bundle deflections of about 0.5 micron evoked average maximal transduction currents of about 325 pA, wherea
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Jia, Shuping, and David Z. Z. He. "Motility-associated hair-bundle motion in mammalian outer hair cells." Nature Neuroscience 8, no. 8 (2005): 1028–34. http://dx.doi.org/10.1038/nn1509.

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Biswas, Joyshree, Robert S. Pijewski, Rohit Makol, et al. "C1ql1 is expressed in adult outer hair cells of the cochlea in a tonotopic gradient." PLOS ONE 16, no. 5 (2021): e0251412. http://dx.doi.org/10.1371/journal.pone.0251412.

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Hearing depends on the transduction of sounds into neural signals by the inner hair cells of the cochlea. Cochleae also have outer hair cells with unique electromotile properties that increase auditory sensitivity, but they are particularly susceptible to damage by intense noise exposure, ototoxic drugs, and aging. Although the outer hair cells have synapses on afferent neurons that project to the brain, the function of this neuronal circuit is unclear. Here, we created a novel mouse allele that inserts a fluorescent reporter at the C1ql1 locus which revealed gene expression in the outer hair
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Chertoff, M. E., and W. E. Brownell. "Characterization of cochlear outer hair cell turgor." American Journal of Physiology-Cell Physiology 266, no. 2 (1994): C467—C479. http://dx.doi.org/10.1152/ajpcell.1994.266.2.c467.

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The cochlear outer hair cell (OHC) is a cylindrical cell with structural features suggestive of a hydraulic skeleton, i.e., an elastic shell with a positive internal pressure. This study characterizes the role of the OHC elevated cytoplasmic pressure in maintaining the cell shape. Intracellular pressure of OHCs from guinea pig is estimated by measuring changes in cell morphology in response to increasing or decreasing osmolarity. Cells collapse when subjected to a continuous increase in osmolarity. Collapse occurs at an average of 8 mosM above the standard medium, suggesting that normal cells
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Wada, Hiroshi. "Mechanics of inner and outer hair cells." AUDIOLOGY JAPAN 59, no. 3 (2016): 161–69. http://dx.doi.org/10.4295/audiology.59.161.

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Dissertations / Theses on the topic "Outer hair cells"

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Jagger, Daniel James. "Modulation of ion channels in outer hair cells from the mammalian cochlea." Thesis, University of Bristol, 1996. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.336876.

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Richmond, Sarah Jane. "A study of in situ outer hair cells from the adult mammalian cochlea." Thesis, University of London, 1999. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.313691.

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Gale, Jonathan Edward. "Mechanosensitivity of the basolateral membrane of outer hair cells from the mammalian cochlea." Thesis, University of Bristol, 1994. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.240651.

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Liang, Guihua. "K⁺ channels in the inner ear : electrophysiological and molecular studies /." Stockholm, 2005. http://diss.kib.ki.se/2005/91-7349-971-4/.

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Abou, Dakka Milad. "Linear oscillatory dynamics of flexoelectric membranes embedded in viscoelastic media with applications to outer hair cells." Thesis, McGill University, 2013. http://digitool.Library.McGill.CA:80/R/?func=dbin-jump-full&object_id=114535.

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Membrane flexoelectricity is an electromechanical coupling effect between the membrane average curvature and macroscopic electric polarization. Flexolelectricity is a biological actuation mechanism involved in the functioning of hearing. This thesis uses theory and simulation to develop a fundamental understanding of flexolectricity of relevance to hearing processes by integrating membrane elasticity and flexolectricity with viscoelastic processes. Flexoelectric actuation uses an imposed electric field to create membrane bending. In this thesis we model the small amplitude oscillatory dy
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Spreadbury, Ian Clive. "Single channel recordings form the BK channels of outer hair cells of the guinea pig cochlea." Thesis, University of Bristol, 2000. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.322611.

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Roberts, Terri Patricia. "Developmental failure in cochlear hair cells from mouse models of Usher syndrome and the identification of an acid sensitive ionic current in Inner and Outer hair cells." Thesis, University of Sussex, 2013. http://sro.sussex.ac.uk/id/eprint/46460/.

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Inner hair cells (IHCs) are the primary sensory receptors of the mammalian cochlea. I employed the whole-cell patch-clamp technique to study voltage responses and ionic currents of IHCs in mice bearing mutations in hair bundle proteins. These mutations, all associated with Usher syndrome, lead to structural and functional defects of the mechanosensory hair bundle. I observed developmental failure in the electrical properties of IHCs from these mutants: a continuation of neonatal spiking instead of the graded receptor potentials seen in control adult IHCs. Voltage-clamp recordings revealed the
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Wilson, Caroline Lesley. "The hair follicle : studies of the outer root sheath in health and disease, and a possible role for the bulge." Thesis, Imperial College London, 1995. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.309741.

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Leitner, Michael [Verfasser], and Dominik [Akademischer Betreuer] Oliver. "Molecular Properties and Pathophysiological Relevance of the Predominant K+ Conductance in Cochlear Outer Hair Cells / Michael Leitner. Betreuer: Dominik Oliver." Marburg : Philipps-Universität Marburg, 2012. http://d-nb.info/1027183662/34.

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Wright, Daniel. "Anatomical and electrophysiological investigation of the distribution of acetylcholine receptors in the post synaptic membrane of mammalian cochlear outer hair cells." Thesis, Keele University, 2002. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.250420.

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Books on the topic "Outer hair cells"

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Iwasa, Kuni H. Electromotility of outer hair cells. Oxford University Press, 2010. http://dx.doi.org/10.1093/oxfordhb/9780199233397.013.0006.

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Rinehart, Dawn Reneé. Ultrastructural study of the outer hair cells of the cochlea. 1996.

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Mason, Peggy. Audition. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190237493.003.0016.

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Hearing loss is devastating because it prevents communication through verbal language and thereby produces social isolation. The experience of hearing loss or deafness is the most common sensory deficit. The experience of affected individuals is highly variable because it depends on age of onset and treatment efficacy, among many factors. The roles of the external and middle ears in conduction and of the internal ear in sensorineural processing are used as a framework for understanding common forms of hearing loss. The contributions of inner and outer hair cells to cochlear function are detail
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Book chapters on the topic "Outer hair cells"

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Ashmore, J. F. "Transducer Motor Coupling in Cochlear Outer Hair Cells." In Cochlear Mechanisms: Structure, Function, and Models. Springer US, 1989. http://dx.doi.org/10.1007/978-1-4684-5640-0_13.

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Hackney, Carole M., David N. Furness, and Peter S. Steyger. "Structural Abnormalities in Inner Hair Cells Following Kanamycin-Induced Outer Hair Cell Loss." In Lecture Notes in Biomathematics. Springer New York, 1990. http://dx.doi.org/10.1007/978-1-4757-4341-8_2.

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Forge, Andrew. "The Lateral Walls of Inner and Outer Hair Cells." In Cochlear Mechanisms: Structure, Function, and Models. Springer US, 1989. http://dx.doi.org/10.1007/978-1-4684-5640-0_4.

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Neely, S. T. "A Model for Bidirectional Transduction in Outer Hair Cells." In Cochlear Mechanisms: Structure, Function, and Models. Springer US, 1989. http://dx.doi.org/10.1007/978-1-4684-5640-0_9.

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Song, Lei, and Joseph Santos-Sacchi. "A Walkthrough of Nonlinear Capacitance Measurement of Outer Hair Cells." In Methods in Molecular Biology. Springer New York, 2016. http://dx.doi.org/10.1007/978-1-4939-3615-1_28.

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Schneider, Marie, Christina Dieckmann, Katrin Rabe, Jan-Christoph Simon, and Vuk Savkovic. "Differentiating the Stem Cell Pool of Human Hair Follicle Outer Root Sheath into Functional Melanocytes." In Stem Cells and Tissue Repair. Springer New York, 2014. http://dx.doi.org/10.1007/978-1-4939-1435-7_16.

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Brownell, William E., Wafaa E. Shehata, and John P. Imredy. "Slow Electrically and Chemically Evoked Volume Changes in Guinea Pig Outer Hair Cells." In Biomechanics of Active Movement and Deformation of Cells. Springer Berlin Heidelberg, 1990. http://dx.doi.org/10.1007/978-3-642-83631-2_21.

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Zenner, Hans Peter, and Detlev Drenckhahn. "Direct Evidence for an Active Mechanical Process in Mammalian Outer Hair Cells." In Auditory Frequency Selectivity. Springer US, 1986. http://dx.doi.org/10.1007/978-1-4613-2247-4_11.

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Mountain, D. C., and A. R. Cody. "Mechanical Coupling between Inner and Outer Hair Cells in the Mammalian Cochlea." In Cochlear Mechanisms: Structure, Function, and Models. Springer US, 1989. http://dx.doi.org/10.1007/978-1-4684-5640-0_19.

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Evans, B. N., P. Dallos, and R. Hallworth. "Asymmetries in Motile Responses of Outer Hair Cells in Simulated in Vivo Conditions." In Cochlear Mechanisms: Structure, Function, and Models. Springer US, 1989. http://dx.doi.org/10.1007/978-1-4684-5640-0_25.

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Conference papers on the topic "Outer hair cells"

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Iwasa, Kuni H., and Xiao-Xia Dong. "Motor noise in outer hair cells." In SPIE's First International Symposium on Fluctuations and Noise, edited by Sergey M. Bezrukov, Hans Frauenfelder, and Frank Moss. SPIE, 2003. http://dx.doi.org/10.1117/12.497616.

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HE, D. Z. Z. "MECHANICAL RESPONSES OF COCHLEAR OUTER HAIR CELLS." In Proceedings of the International Symposium. WORLD SCIENTIFIC, 2003. http://dx.doi.org/10.1142/9789812704931_0024.

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Brownell, William E., Anthony W. Gummer, Christopher A. Shera, and Elizabeth S. Olson. "Outer Hair Cells and Prestin—A Moderated Discussion." In WHAT FIRE IS IN MINE EARS: PROGRESS IN AUDITORY BIOMECHANICS: Proceedings of the 11th International Mechanics of Hearing Workshop. AIP, 2011. http://dx.doi.org/10.1063/1.3658168.

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JIA, SHUPING, JIAN ZUO, PETER DALLOS, and DAVID Z. Z. HE. "THE COCHLEAR AMPLIFIER: IS IT HAIR BUNDLE MOTION OF OUTER HAIR CELLS?" In Proceedings of the Ninth International Symposium. WORLD SCIENTIFIC, 2006. http://dx.doi.org/10.1142/9789812773456_0045.

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MEYER, JENS, and ANTHONY W. GUMMER. "TIP-LINK INDEPENDENT MECHANOTRANSDUCTION IN COCHLEAR OUTER HAIR CELLS?" In Proceedings of the International Symposium. WORLD SCIENTIFIC, 2000. http://dx.doi.org/10.1142/9789812793980_0038.

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Frosch, Reinhart. "Human otoacoustic emissions generated by active outer hair cells." In ICA 2013 Montreal. ASA, 2013. http://dx.doi.org/10.1121/1.4799218.

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IWASA, K. H. ""AREA CHANGE PARADOX" IN OUTER HAIR CELLS' MEMBRANE MOTOR." In Proceedings of the Ninth International Symposium. WORLD SCIENTIFIC, 2006. http://dx.doi.org/10.1142/9789812773456_0027.

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DINKLO, T., S. M. VAN NETTEN, W. MARCOTTI, and C. J. KROS. "SIGNAL PROCESSING BY TRANSDUCER CHANNELS IN MAMMALIAN OUTER HAIR CELLS." In Proceedings of the International Symposium. WORLD SCIENTIFIC, 2003. http://dx.doi.org/10.1142/9789812704931_0008.

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GLASSINGER, E., and R. M. RAPHAEL. "THEORETICAL ANALYSIS OF MEMBRANE TETHER FORMATION FROM OUTER HAIR CELLS." In Proceedings of the Ninth International Symposium. WORLD SCIENTIFIC, 2006. http://dx.doi.org/10.1142/9789812773456_0034.

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FETTIPLACE, R., A. C. CRAWFORD, and H. J. KENNEDY. "SIGNAL TRANSFORMATION BY MECHANOTRANSDUCER CHANNELS OF MAMMALIAN OUTER HAIR CELLS." In Proceedings of the Ninth International Symposium. WORLD SCIENTIFIC, 2006. http://dx.doi.org/10.1142/9789812773456_0043.

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Reports on the topic "Outer hair cells"

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Zuo, Jian. Therapeutics for Regeneration of Fully Functional Auditory Outer Hair Cells. Defense Technical Information Center, 2012. http://dx.doi.org/10.21236/ada569196.

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