Academic literature on the topic 'Other cultural studies, n.e.c'
Create a spot-on reference in APA, MLA, Chicago, Harvard, and other styles
Consult the lists of relevant articles, books, theses, conference reports, and other scholarly sources on the topic 'Other cultural studies, n.e.c.'
Next to every source in the list of references, there is an 'Add to bibliography' button. Press on it, and we will generate automatically the bibliographic reference to the chosen work in the citation style you need: APA, MLA, Harvard, Chicago, Vancouver, etc.
You can also download the full text of the academic publication as pdf and read online its abstract whenever available in the metadata.
Journal articles on the topic "Other cultural studies, n.e.c"
1
Dash, R., and A. S. Bhattacharyya. "Геометрическая форма областей разрушения в ходе скользящей наноиндентации тонких пленок Si-C-N, применяемых для Н/МЭМС." Письма в журнал технической физики 48, no. 15 (2022): 3. http://dx.doi.org/10.21883/pjtf.2022.15.53122.19132.
Full textAbstract:
The failure regions during sliding nano indentation of technologically important SiCN thin films resembled geometrical shapes of Lemniscate and cardiod. An adhesive strength of 9 GPa was estimated. The failure followed two different stress regimes, one tangential responsible for the wear and the other axial responsible for the film/substrate adhesion. EDS spectra of the scratched region shown complete adhesive failure.
2
JURASEK, Miroslav, Tomislav POTOCKY, and Tereza VACINOVA. "F O R E I G N L A N G U A G E T E A C H I N G M E T H O D O L O G Y." Ezikov Svyat (Orbis Linguarum) 18, no. 1 (March 27, 2020): 148–55. http://dx.doi.org/10.37708/ezs.swu.v18i1.18.
Full textAbstract:
The capability to use cultural cues in order to function effectively in culturally diverse situations has been measured by the fashionable concept of cultural intelligence (CQ) and its four dimensions (metacognitive CQ, cognitive CQ, motivational CQ and behavioral CQ) in a lot of previous studies and research. This capability is an important asset of the competitive portfolio for almost all companies in today's globalized world. Our study builds on a recent intensive research and brings anew the issue of CQ into the Czech environment. Specifically, the relationship between language skills and cultural intelligence is examined. Using the PLS – SEM statistical method, a sample of 100 respondents studying in the English BA program at one Czech private university and coming from different countries (mostly from China) was analyzed to demonstrate that there was a positive correlation between foreign language proficiency and all dimensions of CQ. On the contrary, another hypothesis (proposed in one previous study) was not confirmed: purposeful preparation for a language exam and its successful passing does not stimulate the development of the motivational (or any other) dimension of CQ or, in any case, no significant difference was found between the two groups of those who possess a language certificate and those who do not.
3
Houari, Mouna, Asmaa Biaz, Fatima Bighouab, Leila Laamara, Samira Elmachtaniidrissi, Sanae Bouhsain, and Abdellah Dami. "The Contribution of High Performance Liquid Chromatography to the Incidental Discovery of Hemoglobin Variants during Glycated Hemoglobin Assay." Cross Current International Journal of Medical and Biosciences 3, no. 9 (December 30, 2021): 88–92. http://dx.doi.org/10.36344/ccijmb.2021.v03i09.002.
Full textAbstract:
HbA1c is assayed in the biochemistry laboratory using a high pressure liquid chromatography (HPLC) technique in ion exchange, and given the correlation between its value and the risk of complication, it is crucial to know it, advantages and it limits. This work highlights the contribution of HPLC in the detection of qualitative abnormalities of hemoglobin during the determination of HbA1c using the ADAMS HA-8180V ARKRAY® device. This descriptive prospective study, carried out at the Biochemistry-Toxicology department of the Mohammed V Military Hospital in Rabat, focused on all samples for which routine HbA1c testing is prescribed during the past year, external samples and from all departments. For each abnormality noted on the chromatogram, a complete study of hemoglobin was performed using other electrophoretic technique at alkaline and acid pH on the Capillarys 2 Flex Piercing® Sebia® and the Hydrasys 2 Scan Focusing® Sebia®. Almost 0.6% of the variants were detected during the HbA1c assay out of 12,944 blood samples.Only 0.04% were not identified by the machine. After confirmation, variant C was predominantly present (n = 30), followed by S (n = 28) then O-Arab (n = 8) and l 'Hb D (n =2). The HPLC technique, for measurement of HbA1c, represents a reliable screening tool for the most common variants of Hb, with however limitations that encourage vigilance in the analysis and interpretation of the results.
4
DANYLІUK, N. O. "UKRAINIAN LINGUO-FOLKLORE STUDIES: THEIR HISTORY, CURRENT STATE, AND PERSPECTIVES." Movoznavstvo 320, no. 5 (October 28, 2021): 34–48. http://dx.doi.org/10.33190/0027-2833-320-2021-5-003.
Full textAbstract:
The article is devoted to the evolution, present state and perspectives of development of the Ukrainian linguo-folklore studies that are conducted by Sv. Yеrmolenko, N. Zhuravliova, A. Moisiienko, T. Betsenko, Y. Diadyshcheva-Rosovetska, N. Kolesnyk, R. Serdeha and others. The main aspects of the analysis of the language of the Ukrainian folk poetic texts of the period from the end of the 19th century until the middle of the 20th century were considered. They are historical linguistic, linguo-stylistic, linguo-didactic, linguo-cultural, ethnolinguistic, linguo-conceptual, linguo-semiotic. Two stages in the development of linguo-folklore studies were distinguished: 1) 60s — 80s of the 20th c., and 2) 90s of the 20th c. — the early 21st c. It was pointed out that the Ukrainian linguo-folklore studies had already evolved into a separate branch of philology and an educational course with its own object (a linguostructural, artistic-figurative organization of folkloristic texts of various genres, peculiar features of a folkloristic style formation), and subject of research, tasks and trends. There were mentioned the present day approaches to the analysis of folk poetic texts, being based on the language layers (folklore stylistics of language units), language expressive means (folklore stylistics of language expressive means), genres (folklore stylistics of genres) and separate parts of linguistics. The following perspectives of the linguo-folklore studies were defined: the analysis of understudied language units and figurative means, used in the texts of various genres (not only the traditional but new ones as well), development of a folklore lexicography, folklore dialectology, folklore linguo-cognitology, folklore linguosemiotics, folklore communication, linguo-genderology, contrastive linguo-folklore studies, and other trends, as well as a wider application of modern systems of an automatic analysis of texts, dictionaries’ compilation, and data creation.
5
Domino, George, Sulin Su, and Di Shen. "Cross-Cultural Investigation of a New Set of Scales for the Suicide Opinion Questionnaire." OMEGA - Journal of Death and Dying 41, no. 4 (December 2000): 307–21. http://dx.doi.org/10.2190/uhux-k5kx-yhdj-bgcl.
Full textAbstract:
There are a number of alternate ways to score the Suicide Opinion Questionnaire (SOQ). Two methods were compared in this study, a set of eight scales developed by content analysis, and a set of five scales developed by factor analysis; two samples, one from the United States ( N=218), and one from Taiwan ( N=291) were assessed. On all SOQ scales, significant mean differences were obtained between U.S. and Taiwanese samples. The patterns of intercorrelations suggest that despite their factor analytic genesis, several of the SOQ-F scales correlate significantly with each other as well as with the SOQ-C scales. The results support the cross-cultural applicability and reliability of the SOQ, and suggest that although the SOQ-F scales may represent interesting variables, they are not superior psychometrically to the original content scales.
6
Polivanova, Anastasia K. "Accentuation of i-verbs in the Sixteenth-century Chronograph from the E. V. Barsov Collection." Slovene 7, no. 2 (2018): 47–61. http://dx.doi.org/10.31168/2305-6754.2018.7.2.2.
Full textAbstract:
The present article describes the accentual system of the verbs featuring the thematic vowel -i- in the late 16th-century Chronograph from the E. V. Barsov collection, held in the State Historical Museum in Moscow, catalogue number 1695. One of the tasks of this article is to show the distribution of the i-verbs in the Barsov Chronograph into three accentual paradigms. A table is presented that renders evident the differentiation in particular sub-paradigms of stress in verbs relating to various accentual paradigms. Particular attention is given to accented word forms of the n-participle. This research project has shown that the i-verbs of the Barsov Chronograph exhibit stress patterns typical for the late sixteenth century, with the exception of three important features, two of which constitute innovations, while the third is an archaism. Firstly, the first-person Present for the accentual paradigm c in the Barsov Chronograph has stress on the ending, like other word forms of the Present tense (in early Old Russian, first person forms are defined as enclinomena, and their transformation into stress-bearing word forms happened in various dialects at various times). Secondly, the l-participle for the accentual paradigm c in the Barsov Chronograph has stress on the suffix (in contrast to the mobile stress that was still broadly present in other texts at that time). Thirdly, the stress in n‑participles of the accentual paradigm b has the same distribution that was reconstructed by A. A. Zaliznyak for early Old Russian, although it has not been observed in a single russian manuscript before.
7
Jo Smith, Tyler, and N. P. Milner. "Votive Reliefs from Balboura and its Environs with an Epigraphical Appendix." Anatolian Studies 47 (December 1997): 3–49. http://dx.doi.org/10.2307/3642898.
Full textAbstract:
Seventy-five votive reliefs have been identified from the survey of the Balboura city site and the west part of its territory. Several reliefs include inscriptions, yielding crucial information about their date and function in Greco-Roman northern Lycia; these are studied by N. P. Milner in the epigraphical appendix. This paper presents a catalogue of the reliefs, an analysis of the iconographic types and distribution outside the survey area, and an examination of their location and function. Prior to extensive survey of the Balboura area many of the reliefs were undiscovered and unpublished. This treatment of the votive reliefs aims to increase our knowledge of religious life and art at Balboura—first during its period of hellenisation (from c. 200 B.C.), and later as a small urban centre of the eastern Roman Empire. The majority of reliefs are rock-cut and remain in situ; the others are carved on slabs. The general condition of the reliefs is poor. Many are badly weathered, as well as being of a generally low artistic standard.
8
Dalal, RC, and RJ Mayer. "Long term trends in fertility of soils under continuous cultivation and cereal cropping in southern Queensland .VI. Loss of total nitrogen from different particle size and density fractions." Soil Research 25, no. 1 (1987): 83. http://dx.doi.org/10.1071/sr9870083.
Full textAbstract:
The dynamics of total N in particle-size and density fractions of six major soils which have been used for cereal cropping for 20-70 years were studied in order to identify the labile organic matter fractions in soil. For virgin soils, no single particle-size was consistently enriched in N as compared with the whole soil. The clay fraction contained the largest proportion (53% overall) of total N. Silt-size and sand-size N fractions accounted for 26% and 21% of total N, respectively. Upon cultivation, the sand-size fraction lost most of its N (as much as 89% in Langlands-Logie soil). However, N losses also occurred from silt-size and clay-size fractions in most soils. Changes in C : N ratios of different particle-size fractions upon cultivation were not consistent in all soils, possibly because of the transfer of organic C and N among these fractions. Therefore, the separation of labile organic matter fractions from the whole soil based upon particle-size may not be successful in all soils. On the other hand, the density fractionation of soil into a light fraction (<2 Mg m-3) containing relatively labile organic matter (76-96% lost upon cultivation) and a heavy fraction (>2 Mg m-3) containing less labile organic matter appears to be more successful in most soils. It is suggested that the cultural practices that enhance the amount of light fraction would increase the rate of nutrient cycling through microbial biomass and may increase the overall availability of nutrients in soil.
9
Kaal, Joeri, María Guadalupe Castro González, Antonio Martínez Cortizas, and María Pilar Prieto Martínez. "Use of Thermally Assisted Hydrolysis and Methylation (THM-GC-MS) to Unravel Influence of Pottery Production and Post-Depositional Processes on the Molecular Composition of Organic Matter in Sherds from a Complex Coastal Settlement." Separations 8, no. 9 (September 1, 2021): 140. http://dx.doi.org/10.3390/separations8090140.
Full textAbstract:
Ceramic fragments from the Islet of Guidoiro Areoso (NW Spain), covering a wide range of cultural periods (Neolithic to Late Bronze Age), have been studied by color analysis, elemental analysis of carbon (C) and nitrogen (N), and molecular analysis (thermally assisted hydrolysis and methylation, THM-GC-MS), in order to identify the organic matter (OM) in the prehistoric pottery and reveal information on ceramic production techniques, food remains and post-depositional effects. Results showed that the strong marine influence (sherds recovered from coastal deposits) and microbial activity (recovery from waste deposits, “cuncheiros”) had a profound effect on C/N ratio and molecular composition (N-rich protein and chitin structures). Other organic ingredients originated from the material used for creating the ware (detected as pyrogenic OM) and possibly food remains (fatty acid fingerprints). Dark-colored ware was enriched in both pyrogenic OM from incomplete combustion and non-bacterial fatty acids. Fatty acid patterns could not be related to possible vessel use, and markers of aquatic resources were scarce, or absent. It is argued that THM-GC-MS of pottery fragments is useful for understanding how an archaeological deposit developed in time, what kinds of OM are present, and possibly to make a pre-selection of samples with high potential for more cost-demanding dietary molecular assessments.
10
Furman, A. "A THEORETICAL MODEL OF EMPATHIC INTERACTION BETWEEN A PSYCHOLOGIST AND A CLIENT: A CYCLICAL-ACTION APPROACH." Psychology and Personality, no. 2 (October 6, 2022): 9–40. http://dx.doi.org/10.33989/2226-4078.2022.2.265484.
Full textAbstract:
The interdisciplinary study is devoted to the elucidation of the author's concept of the deed integral, developmentally enriched and dialogically directed empathic interaction of a psychologist with clients of different ages, gender, mental experience, social status and mental organization of the individual self. The proposed concept was created, on the one hand, through a reflexive reconstruction of the content of the psychological theory of empathy known in Ukraine and abroad (L.P. Zhuravlyova, 2007), when it is step-by-step achieved, scenario-worked out and practically realized, mutual complementation of the developmental functioning of various types, levels and stages of the empathic process, resources, channels and means of empathic attitudes-relationships and individual psychological features of empathy of each participant in dialogic contact in the "psychologist-client" system, on the other hand - due to the use of the latest methodological optics of post-non-classical rationality, namely the author's cyclical-action approach with its basic principles (cyclicity, synergy, action, metasystem), a number of regularities and norms of cognitive thinking activity. Moreover, the universal tool for implementing research consciousness into life, which establishes the epistemological core of the concept advocated here, is a m e n t a l s c h e m e built according to the principle of quaternity in the context of the broad intellectual possibilities of the innovative sphere of professional methodologization (A.V. Furman, 2005, 2016). The starting idea in this case was the axiomatic statement that the process cycle of the current course of empathy is a separate, original act on the part of the individual. Taking into account the goal, task and subject field of this study, it is proved that: firstly, the most effective technology of collaborative psycho-spiritual filling of interpersonal relationships is modular-developmental interaction, which is first subject to a reflexive-action scripting, and then to a full-fledged existential implementation; secondly, the stages of deployment of personified empathic interaction can not only be justified on the basis of dominant processes (affective, cognitive, conative), but also more methodologically justified on the basis of the logic-canonical structure of the act (situation, motivation, action, afteraction); thirdly, the empathic dialogic cycle is best consciously organized by a practical psychologist while working with a client as a four-periodized and step-by-step (procedural) detailed act of personal empathy, which includes the alternating dominance of natural, affective-cognitive, conative-active and reflective types of empathy; fourthly, the psychologist's practical use of the action-reflective thinking scheme of the scenario confirmed the empirical effectiveness in his individual work with students of secondary and higher education, in particular with those who have special needs or are characterized by problematic behavior.
Books on the topic "Other cultural studies, n.e.c"
1
Sklare, David Eric. Samuel ben Ḥofni Gaon and his cultural world: Texts and studies. Leiden: E.J. Brill, 1996.
Find full text
2
1940-, Lasseter Janice Milner, and Harris Sharon M, eds. Rebecca Harding Davis: Writing cultural autobiography. Nashville: Vanderbilt University Press, 2001.
Find full text
3
1968-, Pierce Steven, and Rao Anupama, eds. Discipline and the other body: Correction, corporeality, colonialism. Durham: Duke University Press, 2006.
Find full text
4
Arlene, Brett, and McCloskey Gary N, eds. Computers, curriculum, and cultural change: An introduction for teachers / Eugene F. Provenzo, Jr., Arlene Brett, Gary N. McCloskey. 2nd ed. Mahwah, N.J: L. Erlbaum, 2005.
Find full text
5
B, Dohrmann Natalie, and Stern David 1949-, eds. Jewish biblical interpretation and cultural exchange: Comparative exegesis in context. Philadelphia: University of Pennsylvania Press, 2008.
Find full text
6
Pandora's handbag: Adventures in the book world. London: Serpent's Tail, 2001.
Find full text
7
Iley, Chrissy. Men, women, love, sex, God & death: The collected Sunday Times writings. London: Andre Deutsch, 1997.
Find full text
8
Composer to composer: Conversations about contemporary music. St Leonards, NSW, Australia: Allen & Unwin, 1993.
Find full text
9
As I please: Selected writings 1975-1994. London: Skoob Books Pub., 1994.
Find full text
10
Núñez, Benjamín. Dictionary of Portuguese-African civilization. London: Hans Zell Publishers, 1995.
Find full textBook chapters on the topic "Other cultural studies, n.e.c"
1
Kjellström, Anna. "From Saint to Anthropological Specimen: The Transformation of the Alleged Skeletal Remains of Saint Erik." In Bioarchaeology and Social Theory, 167–88. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-031-03956-0_7.
Full textAbstract:
AbstractErik Jedvardsson, king of Sweden, was slain in c. AD 1160 and has been venerated as a saint since the end of the twelfth century. It is clear from historical records and osteological studies that the bones, kept in a reliquary in Uppsala Cathedral, have received much attention over the centuries. Initially they served as intercessors with God and were reverently touched and divided for distribution to other institutions. After the Reformation the remains were kept in a reliquary and exclusively functioned as heirlooms embodying a legendary fallen king. In the Age of Enlightenment, the authenticity of the bones came under scrutiny. Eventually, they turned into subjects of scientific research and no less than three thorough anthropological investigations have been conducted since 1915. The transformation of Saint Erik’s body from a Christian relic to an anthropological specimen not only testifies to the strong agency of the remains but can be traced to several shifts in the ‘cultural paradigm’. Although the historical understanding of the medieval king has not changed significantly over time, these paradigm shifts have inevitably affected the narrative and how the bones have been handled.
2
Alnakhi, Wafa K., Faryal Iqbal, Waleed Al Nadabi, and Amal Al Balushi. "Challenges Associated with Medical Travel for Cancer Patients in the Arab World: A Systematic Review." In Cancer in the Arab World, 427–44. Singapore: Springer Singapore, 2022. http://dx.doi.org/10.1007/978-981-16-7945-2_27.
Full textAbstract:
AbstractIntroduction: Each year, millions of patients around the world seek medical care abroad. Medical travel is becoming very common in the Gulf Cooperation Council Countries (GCC) due to many motivational factors. It has been observed that the rate of cancer incidence is growing at an alarmingly high rate in Arab countries. In addition, as per the literature, cancer seems to be one of the top medical conditions for patients from the GCC to seek healthcare overseas. There are many factors associated with cancer patients seeking treatment overseas. However, unfortunately, there are very few studies that discuss the risks and challenges associated with the medical travel experience for those patients.Objective: We conducted a systematic review to summarize the evidence related to the complications and challenges associated with the medical travel experience for oncology patients in the Arab world.Materials and Methods: This systematic review was guided by PRISMA. PubMed was used as a search database by using a combination of medical travel, complications, and cancer keywords for publications which yielded 76 articles. Four coders independently determined eligibility based on PICOS and then extracted information from 14 articles. The resulting articles are based on three main categories, i.e., primary, and secondary data collection, and review articles.Results: Of the total 76 articles, only 14 were included because they met the criteria. 62 articles were excluded because of irrelevance of the title, abstract, and insufficient data. Although this systematic review aimed to look at the medical complications that may arise from the medical travel experience for oncology patients, other challenges were found. The challenges reported can be grouped into the following themes: (a) financial and economic aspects, (b) medical care aspects, (c) social and cultural aspects.Conclusion: Overall, more research studies are required in the Arab world for cancer patients treated overseas. The existence of such information around this topic will help in improving policies and strategies related to medical travel for the different stakeholders involved in the medical travel market. Moreover, these studies will not only aid in improving the quality of care for cancer patients who are engaging in medical travel, but they will also help in overcoming the challenges associated with medical travel experience for cancer patients at the different stages of the experience.
3
Roy, Parimal, jahid siraz chowdhury, Haris Abd Wahab, Mohd Rashid Bin Saad, and Suma Parahakaran. "Christianity, COVID-19, and Marginal People of Bangladesh." In Advances in Religious and Cultural Studies, 65–82. IGI Global, 2021. http://dx.doi.org/10.4018/978-1-7998-7480-5.ch005.
Full textAbstract:
This chapter aims to discuss the correlation between Indigeneity and Christianity in the context of Bangladesh's Santal community during this pandemic C-19. Methodologically, this study informs the Indigenous research paradigm. As instruments, this study adopted interviews, observational fieldwork, and sharing circle for primary data collection. Authors scrutinized census reports and other governmental and NGO reports for secondary information. Findings show that the Christian commonwealth faith has been very predominant during this pandemic among the Santals. Collaboration among the churches, NGOs, and government is recommended for the new normal and further crisis management.
4
Pawar, V. P., Bhagyashree Kunte, and Srinivas Tumuluri. "Tata’s Air India ‘Take Over to Take Off’—A Cultural Conundrum." In Indian Business Case Studies Volume II, 15—C2.P60. Oxford University PressOxford, 2022. http://dx.doi.org/10.1093/oso/9780192869388.003.0002.
Full textAbstract:
Abstract This case study provides major insights to students and faculty in understanding concepts and major issues on cultural integration in mergers and takeovers especially in such cases of the government’s disinvestment plans and uniquely the new buyer was a last owner 75 years ago of the same entity. From being a public sector unit to shift over to private sector ownership the employees will pose major issues in cultural transformation in their roles. Even students of Strategy Management, Human Resources Management, and executives involved in strategic integration will find this case study very interesting since it is a case study of the happening currently. For N Chandrasekaran, newly appointed chairman of Tata’s Air India, the aviation business has always been a nightmare. With Air India’s CEO designate ?lker Ayci out of the picture, Chandrasekaran’s search for talent has become tougher. He may have to invest disproportionate time to the aviation vertical to turn around Air India and other loss-making airlines.
5
Viejo-Rose, Dacia, and Rachel Killean. "Destruction of Heritage as a Strategy of Mass Violence: Assessing Harm to Inform Meaningful Measures of Repair." In Heritage Reconstruction and People: Integrated Recovery After Trauma, 131–43. Arab Regional Centre for World Heritage, 2022. http://dx.doi.org/10.56500/c-r2111.
Full textAbstract:
This contribution builds upon research into the reconstruction of cultural heritage, reparations, and victimhood in post-conflict settings. It focuses on the example of Cambodia but references other temporally more distant and recent cases as well. It combines legal human rights approaches with those of heritage studies to propose that the harm done to individuals and communities by violence against cultural heritage is more complex than hitherto thought. We explore measures to develop meaningful forms of repair that can contribute to overcoming the long-term effects of cultural violence through processes of the co-creation and development of heritage across generations. Cambodia serves as the main example of how community-led heritage recovery unfolds and of its links to psycho-social recovery. We advocate that psycho-social recovery of the community be considered central to heritage recovery work and not just a hoped-for side-effect.
6
Haselberger, Martina. "The Bigger Picture of Recovery: Conservation Challenges related to Living Heritage and Value and Belief Systems in the Preservation and Reconstruction of Cultural Heritage at Patan Durbar Square." In Heritage Reconstruction and People: Integrated Recovery After Trauma, 275–92. Arab Regional Centre for World Heritage, 2022. http://dx.doi.org/10.56500/c-r2035.
Full textAbstract:
"The monuments at Patan Durbar Square in Nepal have been conserved, recovered, and reconstructed with enormous effort, following the damage and devastation caused by a series of earthquakes in 2015. Collaborative work by the Kathmandu Valley Preservation Trust, the Nepalese Department of Archaeology, the Institute of Conservation at the University of Applied Arts in Vienna, and local craftsmen, working with the local community, has made a significant contribution in this respect. Several factors are decisive for the recovery of cultural heritage after a natural disaster: the availability of craftsmen familiar with traditional construction techniques and of heritage preservation professionals, comprehensive surveys and assessments, building materials, pre-disaster documentation, and the long-term commitment of financial support. How have these factors influenced efforts and progress in the case of Patan Durbar Square? What were the challenges and how were they solved? In Patan, tangible and intangible cultural heritage are closely linked and related to each other. The living culture is an essential characteristic of Patan and of Nepal more generally and so also a major criterion in the site’s inscription on the UNESCO World Heritage list. Safeguarding intangible cultural heritage is just as important as the preservation of tangible artworks and sites. This article examines to what degree craftsmanship, religious practices, and festivities and traditions (cyclical renewal) have represented an advantage or an obstacle for conservation and reconstruction efforts in Patan. The analysis is illustrated with selected case studies, while field-tested solutions for reconciling the preservation of both tangible and intangible heritage are pointed out."
7
Camodeca, Renato, Alex Almici, and M. Cristina Vannini. "The Economic Impact of Universal Design on Cultural Heritage Contribution to SDGs: Evidence from Italian Museums." In Studies in Health Technology and Informatics. IOS Press, 2022. http://dx.doi.org/10.3233/shti220878.
Full textAbstract:
United Nations’ Agenda 2030 highlights the need to “make cities and human settlements inclusive, safe, resilient and sustainable” (SDG 11) and reduce inequalities (SDG 10) for the good health and well-being (SDG 3) of the citizens. Although most Italian museums have been forced to comply with the rules for accessibility in public spaces since 1971 following Law 30/3/1971 n. 118 and, more recently, Legislative Decree 81/2008, in this context, Universal Design can contribute to the achievement of these goals by improving accessibility to spaces, services, and the community’s well-being on the one hand, along with providing a deeper comprehension and awareness of the informational processes on the other hand. In this regard, museum organizations play a critical role in enhancing the quality of life and society’s education by preserving and distributing cultural heritage over time. Despite the large number of studies focused on museum organizations, there is little research that takes into account Universal Design and its macro-and firm-level economic benefits on museum institutions (not-for-profit, public, and private). Considering this research gap, this study’s aim is twofold: 1) to explore how some Italian museums have actually improved their facilities and services according to Universal Design principles and 2) to assess the economic museum accessibility. A qualitative methodology was applied using a questionnaire delivered to eight Italian museum, and collected data was compared. The findings underline how museums’ investments in Universal Design may produce relevant economic benefits, both on the macroeconomic and firm levels, providing guidelines for public policies concerning welfare, transport, environment, education, and well-being. Universal Design principles can lead museums to an increasing convergence toward Sustainable Development Goals, improving their overall economic performance as well as strengthening their role in a more aware and participative society. This study has several relevant implications in terms of both policy and management. Policymakers should promote Universal Design investments in museums in order to ensure accessibility to a greater number of visitors, and cultural institutions should consider accessibility as a specific key management dimension to be monitored and improved.
8
Mansurov, Valeriy A., Elena Y. Ivanova, Elena M. Kolesnikova, Olga N. Mamonova, Anna V. Semenova, Elena E. Shatrova, Olesya V. Yurchenko, and Pavel S. Yuriev. "Professional Dynasties as a Social Resource and Socio-Cultural Capital: Research Directions." In Russia in Reform: Year-Book [collection of scientific articles], 149–75. Federal Center of Theoretical and Applied Sociology of the Russian Academy of Sciences, Moscow, Russian Federation, 2022. http://dx.doi.org/10.19181/ezheg.2022.6.
Full textAbstract:
. In the paper we present some results of the study of the social phenomenon of the professional dynasty as a social resource for the reproduction of professional groups. The relevance of the study is based on its interdisciplinary character (social research, economics, philosophy, psychology, history) and a multidimensional approach to the analysis of the professional succession within the family. The research fi lls the gap in the scientifi c studies of the upward social mobility of the members of the professional dynasty including their use of the cultural, economic and social capital. The research obtains scientifi c novelty since we study various professional groups: engineers, doctors, teachers, diplomats, civil servants, taking into consideration their behavioral and educational family trajectories. We used a combination of qualitative and quantitative research methods: in-depth interviews with experts (N = 40) and members of dynasties (N= 162); the sociological mass survey from 8 regions of Russia (N=1400) and the secondary analysis of statistics of the All- Russian sociological surveys. We present the data on various types of dynasties, their structures and the factors that contribute to the development of professional dynasties
9
Whitley, Michael L. "Using Technology to Examine Cultural Learning of African-Americans." In Advances in Educational Technologies and Instructional Design, 263–94. IGI Global, 2014. http://dx.doi.org/10.4018/978-1-4666-4482-3.ch015.
Full textAbstract:
Police officers frequently work with people of different cultures and those who speak different languages, thus needing to learn cultures (Navarro, 2001). The purpose of this case is to examine the self-perceptions of African-Americans regarding their ability to distinguish deception in interpersonal communication. RQ1: How do African-Americans self-report their ability to detect interpersonal communication deception? RQ2: What behaviors do African-Americans believe are indicators of interpersonal communication deception? The method of study is survey research conducted through SurveyMonkey.com. Participants (n=57) discuss their perceptions of deception in their lives. The results suggest that respondents (80%) believe they are better than others at detecting deception. The literature findings also suggest that African-Americans believe themselves to be more effective at detecting deception within their own ethnic group compared to other ethnic groups. Commensurate with previous deception studies, the current study finds that an array of communication behaviors, believed to be indicative of deceit by other ethnic groups, are also used by African-American respondents.
10
Iram and Gaurav Raheja. "Understanding the Quality of Life of Indian Elderly During COVID-19 Pandemic from Universal Design Perspective." In Studies in Health Technology and Informatics. IOS Press, 2022. http://dx.doi.org/10.3233/shti220820.
Full textAbstract:
India is rapidly growing towards a demographic future where a significant proportion of the population is over 60 years and above. In the COVID-19 pandemic, the restrictions imposed to minimize the virus transmission have a detrimental effect on the Quality of Life (QoL) of the elderly, limiting their mobility and social interaction. As a result, social isolation and loneliness have become significant health issues. This study attempts to understand the QoL of Indian elderly during COVID-19 pandemic from universal design (UD) perspective. The objectives were: (a) Discuss the QoL of Indian elderly during COVID-19; (b) Identify the factors affecting QoL of elderly during pandemic; (c) Find the link between factors associated with QoL and UD philosophy. These objectives were achieved by desk-based literature review and a pilot study of Solanipuram, a typical urban neighborhood in Roorkee located in Northern India. Personal in-depth interview sessions with limited number of (n=20) participants aged 60 years and above; belonging to upper-middle income group, are conducted and analyzed using the inductive thematic technique. The previous research suggests that, to date, QoL has been described as well-being resulting from physical, functional, emotional, social, and environmental factors. Whereas, UD allows for the inclusion of the ‘cultural’ dimension into the discussions. Especially in a country with diversity like India, where elderly discusses the impact of physical distancing, limited mobility, and social interactions on their QoL during COVID-19. This study indicates that the application of UD philosophy in response to pandemic can promote well-being and enhance the QoL of elderly.
Conference papers on the topic "Other cultural studies, n.e.c"
1
Baker, J. B., M. P. McGrogan, C. Simonsen, R. L. Gronke, and B. W. Festoff. "STRUCTURE AND PROPERTIES OF PROTEASE NEXIN I." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644765.
Full textAbstract:
Human foreskin fibroblasts secrete several different serine protease inhibitors which differ in size and protease specificities. These proteins, called protease nexins (PNs) all form SDS-resistant complexes with their protease targets. Fibroblast surface receptors recognize the protease-PN complexes and mediate their delivery to lysosomes. PNI is a 45 kilodalton glycoprotein that rapidly inhibits several arg or lys-specific proteases including trypsin, thrombin, and urokinase (k assoc.∼ 4×l06,∼ 6×105 and ∼ 2×105, m−1s−1 respectively). Like antithrombin III, PNI binds heparin and inhibits thrombin at a vastly accelerated rate in the presence of this glycoaminoglycan. Immunofluorescence studies show that in addition to secreting PNI foreskin fibroblasts carry this inhibitor on their surfaces. PNI cDNA has been cloned and sequenced. A mixed oligonucleotide probe derived from PNI N-terminal sequence was used to probe a foreskin fibroblast cDNA library constructed with λGT10. Identification of PNI cDNAs has been verified by sequencing and by expressing active PNI protein in mammalian cells. The full amino acid sequence of PNI, deduced from cDNA sequencing, is 392 residues long and has 30% homology to antithrombin III. An arg-ser pair 32 residues from the C-terminus of the inhibitor is proposed as the reactive center P1-P1 residues. In the hinge region a lys residue is present in a position occupied by a ginor glu residue in other serpins. PNI mRNA exists in 2 slightly different forms:One (αPNI) yields a thr-arg-ser sequence wherethe other βPNI) yields a thr-thr-gly-ser sequence. The presence of the appropriate splice acceptor sites in the genome indicates that these forms are generated from a single gene by alternative splicing. Expressed aPNI and 0PNI proteins both bind thrombin and urokinase. In foreskin fibroblaststhe α form of PNI mRNA predominates over the β form by about 2:1. In foreskin fibroblast cultures secreted PNI inhibits the mitogenic response to thrombin and regulate secreted urokinase. Purified PNI added to human fibrosarcoma (HT1080) cells inhibitsthe tumor cell-mediated destruction of extracellular matrix and transiently, but dramatically, inhibits tumor cell growth. PNI or PNI-like inhibitors may function at multiple physiological sites. The β form of PNI is virtually identical to a glia-derived neurite promoting factor, the cDNA for which has been recently cloned and sequenced by Gloor et al (1). The neurite outgrowth activity of PNI may result from inhibition of a thrombin-like protease that is associated with neurons, since a number of thrombin inhibitors stimulate neurite extension. Recent immunofluoresence experiments, carried out with D. Hantai (Inserm; Paris) demonstrate that anti-PNI antibody intensely stains neuromuscular synapses. In addition, a PNI-like inhibitor is associated with platelets. At low (0.5 nM <) 125I-thrombin concentrations formation of 125I-thrombin-platelet PNI complexes accounts for most of the specific binding of 125I-thrombin to platelets (2). Although the platelet-associated form of PNI is electrophoretically and immunologically indistinguishable from fibroblast PNI, it does not bind urokinase, suggesting that it may be distinct.(1) Gloor, S., K. Odink, J. Guenther, H. Nick, and D. Monard. (1986) Cell 47:687-693.(2) Gronke, R.S., B.L. Bergman, and J.B. Baker. (1987) J. Biol. Chem. (in press)
2
Hach-Wunderle, V., R. Walter-Fincke, H. K. Beck, and I. Scharrer. "FAMILY STUDIES OF PATIENTS WITH RECURRENT VENOUS THROMBOSES AND INHERITED DISORDERS OF BLOOD COAGULATION OR FIBRINOLYSIS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643045.
Full textAbstract:
Several defects of the coagulation and/or fibrinolytic system have been found to be associated with venous thromboembolism. In young patients with recurrent thromboses or a positive family history, an inherited disorder should be excluded535 young patients with venous thromboses, phlebitis and/or pulmonary embolism were investigated from 1980 until 1986. The first thrombotic event had occurred at an age of less than 45 years.An inborn disorder of the blood coagulation or fibrinolytic system was found in 18 families. Most of them (n=13/18) had a positive family history. In all families either thromboses had occurred in at least one member (n=12/18) and/or the defect could be detected in one of them (n=12/18)Most often we found a deficiency of antithfombin III (n=6). A deficiency of protein C (type I) was detected in 3 and a deficiency of protein S in 5 families. In one patient a combined deficiency of anti thrombin III, protein C and protein S was found. Extensive family studies revealed a deficiency of antithrombin III in the grandmother of the patient, who suffered from arterial thrombosis. A deficiency of plasminogen and an abnormal plasminogen molecule were detected in 2 other families. Defective release of t-PA could be demonstrated in 3 members of one investigated family up to nowSeme family members with either defects of protein C, protein S or plasminogen as well as a defective release of t-PA lack thrombotic events. Furthermore thromboses of mesenteric veins occurred in 2 of 6 patients with anti thrombin III deficiency and in 1 of 5 patients with protein S deficiency. Superficial vein thromboses were mainly found in patients with protein C- or protein S-deficiency
3
Chopra, O. K., E. E. Gruber, B. Alexandreanu, Y. Chen, and W. J. Shack. "Crack Growth Rates of Irradiated Austenitic Stainless Steels in BWR Environments at 289°C." In ASME 2007 Pressure Vessels and Piping Conference. ASMEDC, 2007. http://dx.doi.org/10.1115/pvp2007-26659.
Full textAbstract:
Crack growth rate (CGR) data have been obtained in boiling water reactor environments on several grades of austenitic stainless steels, including weld heat-affected-zone and cast materials, that were irradiated up to 2.0 × 1021 n/cm2 (E > 1 MeV) (≈3 dpa). Crack growth tests were conducted on 1/4-T compact tension specimens subjected to either a sawtooth waveform with load ratios up to 0.7 and rise times up to 1000 s, or a constant load with or without periodic partial unloading. The results indicate significant enhancement of crack growth rates in the irradiated steels. The results are compared with data obtained from other studies. The existing CGR data are also reviewed to evaluate the effects of material composition, irradiation, and water chemistry on the CGRs in austenitic SSs. The significance of specimen size criteria is discussed.
4
Nakajima, T., T. Koyama, Y. Nishida, H. Tanaka, E. Kakishita, and K. Nagai. "INHIBITORY EFFECTS OF ITP SERA ON BINDING OF ANTIPLATELET GLYCOPROTEIN (GP) IIb/IIIa MONOCLONAL ANTIBODIES TO HUMAN UMBILICAL VASCULAR ENDOTHELIAL CELLS (HUVE)." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643363.
Full textAbstract:
Some ITP patients have specific autoantibodies to platelet GP IIb/IIIa. On the other hand, HUVE were shown to synthesize platelet GP IIb/IIIa like substances. Therefore, we studied the binding of ITP sera to HUVE by showing the inhibitory effect of ITP sera on the binding of anti-platelet GP IIb/IIIa monoclonal antibodies to HUVE. HUVE were cultured according to the method of Jaffe et al. 125-I-anti-platelet GP IIb/IIIa monoclonal antibody (125-I-Anti-GP) (40.3 mCi/mg), 40 yl, was added to a cell suspension of HUVE (1.5 × 104/500 μl) in a plastic RIA tube. After incubation for 30 min. at 4°C and centrifugation of 10,000 xg for 3 min., the radioactivity of the cell pellet was measured. Specific binding was determined by determining the difference between cell-bound radioactivity in the absence and presence of an excess amount of unlabelled ligand at 100 x concentrations. Scatchard analysis using 125-I-Anti-GP showed that the maximum binding capacity was 8 × 104/cell and Kd was 40.2 nM. The binding rate of 125-I-Anti-GP to HUVE treated with ITP (high PAIgG) sera (n=6) was 15.2±3.3% compared with 24.0±7.5%, observed for HUVE treated with normal sera (n=10). Treatment of ITP sera to HUVE significantly lowered the binding of 125-I-Anti-GP to HUVE (P<0.05). A combined analysis of SDS-PAGE and Western blotting of washed platelet and endothelial cell lysates shows that two proteins from each cells had similar or identical molecular masses to GP IIb/IIIa.These findings show that there are GP IIb/IIIa on the HUVE, ITP sera from our patients may have antibodies to HUVE GP IIb/IIIa and that anti-platelet GP IIb/IIIa antibodies in the ITP sera may bound not only to some platelets, but also to the HUVE
5
Bolca, Pelin, Rosa Tamborrino, and Fulvio Rinaudo. "Henri Prost in Istanbul: Urban transformation process of Taksim-Maçka Valley (Le parc n°2)." In 24th ISUF 2017 - City and Territory in the Globalization Age. Valencia: Universitat Politècnica València, 2017. http://dx.doi.org/10.4995/isuf2017.2017.5670.
Full textAbstract:
With the foundation of the Republic of Turkey in October 1923, modernization studies have been started throughout the country. The Republican authorities which adopted a new form of government independent of the Ottoman Empire had expectations for the city planning of Turkey according to the modernization rules of urbanism. After the proclamation of the Republic, the capital of the country was relocated from Istanbul to Ankara and the funds of the Republic were canalized to the construction of the new capital city. Following the creation of Ankara, in 1935, French architect and urban planner Henri Prost was invited directly to conduct the planning of Istanbul. He worked between 1936 and 1951 with a conservative and modernist attitude. Prost’s plans for Istanbul was based on three principal issues: the transportation (la circulation), hygiene (l’hygiène) and aesthetics (l’aesthetics). He gave importance on urban and public spaces (espaces libres) and proposed two public parks. One of these parks was considered as an archaeological park at the hearth of the Historical Peninsula (parc n1), the other one was considered as a park with cultural, arts and sports functions into the hearth of the Pera district which was the area extending from today’s Taksim Square to Maçka Valley (parc n2) and wherein these days the modern and new city was built. Only Park No2 (parc n2) was partially constructed in the 1940s following these park plans. However, the park has been transformed by the planning decisions taken over time depending on the political, cultural and ideological changes and this transformation process has been intensively discussed by the academic and professional field on the Istanbul’s and Turkey’s urban agenda. The focus of this study is to understand and define the process of transformation, and investigate the changing of significances of the Taksim-Maçka Valley from foundation of the Republic of Turkey to the present time. Accordingly, the first part of the paper presents the formation process of the area through the 1:2000 plan of Park No2 (parc n2) and the 1:500 plan of The Republic Square and the İnönü Esplanade in Taksim (la place de la République et l'esplanade İnönü à Taksim) which were prepared by Henri Prost. In the second part, the transformation process that occurs after Prost was discharged from his position is analyzed. The paper concludes with a discussion on the pros and cons of the transformation. In the study, the “digital urban history method” (telling the history of the city in the age of the ICT revolution) was used through the power of various direct and indirect sources with ArcGIS and 3D modeling techniques.
6
Heeb, M. J., D. F. Mosher, and J. H. Griffin. "PROTEIN C IS ACTIVATED AND GIVES 110,000 MW COMPLEXES AND PROTEIN S IS CLEAVED AND DECREASED _IN VIVO IN PATIENTS WITH INTRAVASCULAR COAGULATION (DIC)." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644696.
Full textAbstract:
Immunoblotting studies using denaturing and nondenaturing polyacrylamide gel electrophoresis conditions were performed on 100 plasmas from 88 patients with suspected DIC, in order to determine whether the anticoagulant regulatory proteins C and S (PC and PS) cure altered in vivo during DIC. 70 of these plasmas from 65 patients contained 5-35% of PC antigen in the form of activated protein C (APC) complexed with inhibitor(s).24 normal plasmas showed no detectable APC-inhibitor complexes.The complexes in DIC plasmas had a MW of 110 K on SDS-PAGE, as did complexes formed when APC was incubated with plasma immunodepleted of PC, or when PC in normal plasma was activated with Protac C. On nondenaturing gels, the complex present in 69 of 70 patient plasmas had the same mobility as one of two major bands of complexed APC observed in Protac C-activated normal plasma. One patient plasma contained two forms of PC antigen complex. This patient had suffered a perforated uterus during an abortion. After Protac C activation of the patient plasmas, two APC complexed bands were seen. The 16 patients with >15% complexed PC antigen included 3 with severe infection, 5 with solid tumors, 3 with leukemias, 2 with vascular disease and 3 with other diagnoses. These patients had a higher mortality (69%) than the group as a whole and higher levels of fibrin degradation products. 13 of these 16 plasmas and 56 of the entire group of 100 contained a higher than normal proportion of PS in a cleaved form with an apparent molecular weight lower than intact PS on reduced SDS-PAGE. Mean levels of PS antigen determined by electroimmunoassay for 95 of the plasmas were as follows: entire group, 86% (92%); patients with infection (n=34), 76% (81%); patients with malignancy (n=37), 102% (105%); all others (n=24), 70% (74%) wherfe numbers in parentheses exclude patients with liver disease and 100% normal pooled plasma. These studies suggest that PS is cleaved and decreased in vivo and that PC is activated in vivo and complexed with a 50K MW inhibitor(s) during DIC.
7
Znaesheva, Irina V. "STUDY OF COMMUNIST PROPAGANDA IN THE FIRST HALF OF THE 20TH CENTURY: USSR AND USA." In 49th International Philological Conference in Memory of Professor Ludmila Verbitskaya (1936–2019). St. Petersburg State University, 2022. http://dx.doi.org/10.21638/11701/9785288062353.10.
Full textAbstract:
The article analyzes two prominent researches of the 1920–30th (World revolutionary propaganda by H. D. Lasswell and D. Blumenstock and The Language of the Red Army Soldier by I. N. Shpil’rein et al.) and proposes an attempt to look at certain aspects of Soviet science, particularly at the study of linguistic mechanisms of propaganda, not within the framework of a revisionist approach, but including it in the broader scientific and cultural and historical context. The analysis focuses on basically linguistic approaches used by the psychologists, sociologists, and political scientists of the USSR and the USA. The choice of these researches is conditioned, on the one hand, by the mutual interest of the two countries, on the other hand, by the fact that the problem of studying propaganda as a way of spreading communist ideas was equally acute for both countries, albeit with mirror-opposite goals underlying this interest. The analysis of the selected studies demonstrates similarities in study design and methodology. Refs 22.
8
Lillicrap, D., S. Windsor, Benford H. Hoogendorn, and A. R. Giles. "PLATELET VON WILLEBRAND FACTOR: STUDIES IN TYPE II VON WILLEBRAND′S DISEASE VARIANTS." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1644108.
Full textAbstract:
Recent evidence suggests that platelet von Willebrand factor (vWf) plays an important role in maintenance of primary haemostasis. We have studied a normal population (N=24) and 15 patients with variant forms of von Willebrand's disease (vWd) to determine the utility of platelet vWf:Ag measurement in this disorder. Citrated blood was spun at 100 g for 10 mins at 20°C to prepare platelet rich plasma (PRP). The PRP was removed and platelet count and mean platelet volumes (MPV) were determined on a Coulter S+ counter. A platelet button was prepared by centrifugation of PRP at 3,500 g for 15 mins. Plasma supernatant was aspirated and replaced with 900 nl of DH^O. Platelets were lysed by 5 cycles of freeze/thawing and membrane debris pelleted by centrifugation at 13,000 g for 10 mins. Platelet lysate vWf:Ag was measured by a polyclonal anti-vWf ELISA. All platelet samples were tested at least twice. Bleeding times (BT), platelet sensitivity to ristocetin and other factor VIH/vWf parameters were measured by standard methods. vWf molecular weight profiles were assessed by crossed Immunoelectrophoresis and/or by multimer analysis. In 24 normal individuals, mean vWf:Ag was 31 u/109 platelets (7-68). The mean MPV for this group was 8.0 fl. No correlation was seen between MPV and vWf:Ag content. 15 vWd variant patients were studied. No platelet vWf:Ag was found in one type III patient. In two Type Ila patients mean platelet vWf:Ag was 57 u/109 pits. Patients with laboratory features of Type lib vWd showed two patterns of platelet vWf:Ag content. In two families (5 patients) the mean platelet vWf:Ag was only 24 u/109 pits. In this group the MPV was 9.42 fl. and the mean BT 8.75 mins. In the remaining seven Type IIb patients (4 families), the mean platelet vWf:Ag was 105 u/109 pits., MPV 9.1 fl. and mean BT 8 mins. These results in Type lib vWd suggest further heterogeneity within this disease subtype. The finding of a markedly elevated platelet vWf:Ag appears to identify one group of Type lib vWd patients.
9
Foster, D., B. Schach, M. Rudinsky, K. Berkner, A. Kumar, C. Sprecher, F. Hagen, and E. W. bavie. "The Effect of Changes in the Leader Sequence of Human Protein C on Biosynthetic Processing and Gamma-Carboxylation." In XIth International Congress on Thrombosis and Haemostasis. Schattauer GmbH, 1987. http://dx.doi.org/10.1055/s-0038-1643648.
Full textAbstract:
Protein C is the precursor to a serine protease in plasma which contains gamma-carboxy glutamic acid and functions as a potent anticoagulant. Protein C shows considerable structural homology with the other vitamin K-dependent coagulation factors including prothrombin, factor VII, factor IX and factor X. This homology includes the putative pro-peptide region of the prepro leader sequences for these proteins, as well as the leader sequences for gamma-carboxylated proteins from bone. Deletion mutants have been constructed in the cDNA for human protein C in order to test the possibility that the pro-peptide portion of the 42 amino acid leader sequence serves as a molecular signal for gamma-carboxylation. Accordingly, these mutants contain the pre-peptide (hydrophobic leader) plus portions of the pro-peptide at the amino terminus of the light chain. The mutant proteins were expressed in carboxylation-competent mammalian cells and analyzed by barium citrate precipitation and N-terminal amino acid sequencing. These studies have shown that deletions in the pro-peptide region interfere with gamma-carboxylation and removal of the pro-peptide. Deletion of residues −1 through −12 had little effect on the carboxylation or secretion. Deletion of −1 through −17 completely abolished gamma-carboxylation, but had no measurable effect on secretion. Amino terminal sequence analysis of the latter mutant showed that the light chain began with Thr-Pro-Ala-Pro... This corresponds to a sequence in the prepro leader starting at −24. This indicates that the signal peptidase cleavage site for human protein C is between residues −25 and −24 and removal of the pro-peptide had been blocked by the deletion.
10
Richards, Dylan, Frank Schwebel, Adrian Bravo, Matthew Pearson, and Cross-Cultural Addictions Study Team. "A Comparison of Engagement in Cannabis-related Protective Behavioral Strategies across Sex and Cultures." In 2020 Virtual Scientific Meeting of the Research Society on Marijuana. Research Society on Marijuana, 2021. http://dx.doi.org/10.26828/cannabis.2021.01.000.26.
Full textAbstract:
Cannabis-related protective behavioral strategies (PBS) are behaviors used before, during, and/or after using cannabis to reduce its associated harms. Despite the effectiveness of PBS in reducing both cannabis use and negative cannabis-related consequences, few studies have examined whether there are sex and cultural differences in PBS use. In the present study, we compare PBS use across males and females and across five countries. We also examine whether the associations of PBS use with cannabis-related outcomes differ by sex and country. We recruited 1,175 college students (63.3% female; Mage = 20.96, SD = 3.95; 45.1% Freshman, 20.2% Sophomore, 16.6% Junior, 9.7% Senior, 8.4% other) who reported past-month cannabis use from eight universities in five countries (U.S., Spain, Argentina, Uruguay, and the Netherlands) to complete an online survey. The online survey included the Marijuana Use Grid (MUG; Pearson & Marijuana Outcomes Study Team, 2020), Protective Behavioral Strategies for Marijuana scale (PBSM; Pedersen et al., 2016; revised by Pedersen et al., 2017), and Brief-Marijuana Consequences Questionnaire (B-MACQ; Simons et al., 2012). Results of a series of ANOVAs suggested differences across countries on the PBSM total score, F(4, 1,126) = 20.93, p < .001, such that participants in the U.S. (M = 4.53, SD = 1.11) and Spain (M = 4.48, SD = 0.95) endorsed the most frequent PBS use and participants in the Netherlands (M = 3.46, SD = 1.49) endorsed the least frequent PBS use. There were many item-level differences in PBS use across countries with a pattern similar to that for the PBSM total score. Results of a series of independent sample t-tests suggested that females (M = 4.51, SD = 1.11) scored higher than males (M = 4.17, SD =1.09) on the PBSM total score, t(1,123) = -4.88, p < .001, as well as nearly every item. The correlations between PBSM total score and cannabis-related outcomes across gender and countries were mostly in the expected direction: more frequent PBS use was associated with less cannabis use and fewer cannabis-related consequences. These correlations were largest for the U.S. sample. Interestingly, however, the correlation between the PBSM total score and B-MACQ was positive for the Argentina sample and every correlation between the PBSM total score and cannabis-related outcome was positive for the Netherlands sample. The results of the present study suggest there are several gender and cultural differences in the use of cannabis-related PBS. However, future studies are needed to replicate these findings, especially given the relatively small samples for some of the countries in the present study (our smallest sample size was for Uruguay [n = 46]). Gender and cultural differences in PBS use should be considered in developing and tailoring PBS interventions, especially because the PBSM was validated with a U.S. sample and most existing interventions were developed for use with U.S. participants.
Reports on the topic "Other cultural studies, n.e.c"
1
Smith, I. R., S. J. A. Day, R C Paulen, and D. G. Pearson. Chemical studies of kimberlite indicator minerals from stream sediment and till samples in the southern Mackenzie region (NTS 85B, C, F, G), Northwest Territories, Canada. Natural Resources Canada/CMSS/Information Management, 2021. http://dx.doi.org/10.4095/329080.
Full textAbstract:
Till (n=196) and stream sediment (n=60) samples were collected in the area south and west of Great Slave Lake, Northwest Territories (NTS 85B, C, F, and G), over the course of 3 summer field seasons. Samples were processed to recover kimberlite and other indicator minerals. This report summarizes results of the kimberlite indicator mineral (KIM) studies, including measures of KIM mineral types, abundances, and chemistry (major, trace, and rare earth elements). KIMs were present in 24% of the samples collected, and only 183 KIM grains in total were recovered, of which Cr-pyrope garnets were the most abundant (65.6%). Chemical analyses revealed strong similarities to the Drybones Bay and Mud Lake kimberlites which are situated 50 to &gt;100 km to the northeast, roughly aligned with prominent glacially streamlined landform flowsets in this field area. Results suggest there is little evidence for undetected kimberlite outcrop or sub-crop in the study area.
2
Dickman, Martin B., and Oded Yarden. Role of Phosphorylation in Fungal Spore Germination. United States Department of Agriculture, August 1993. http://dx.doi.org/10.32747/1993.7568761.bard.
Full textAbstract:
Spore germination is a common and fundamental event in fungal development and in many instances an essential phase of fungal infection and dissemination. Spore germination is also critical for hyperparasites to function as biocontrol agents as well as in fermentation proceses. Our common objective is to understand the mechanisms which regulated spore germination and identify factors involved in pathogenicity related prepenetration development. Our approach is to exploit the overall similarity among filamentous fungi using both a plant pathogen (Colletotricum trifolii) and a model system that is genetically sophisticated (Neurospora crassa). The simulataneous use of two organisms has the advantage of the available tools in Neurospora to rapidly advance the functional analysis of genes involved in spore germination and development of an economically important fungal phytopathogen. Towards this we have isolated a protein kinase gene from C. trifolii (TB3) that is maximally expressed during the first hour of conidial germination and prior to any visible gene tube formation. Based on sequence similarities with other organisms, this gene is likely to be involved in the proliferative response in the fungus. In addition, TB3 was able to functionally complement a N. crassa mutant (COT-1). Pharmacological studies indicated the importance of calmodulin in both germination and appressorium differentiation. Using an antisense vector from N. crassa, direct inhibition of calmodulin results in prevention of differentiation as well as pathogenicity. Both cAMP dependent protein kinase (PKA) and protein kinase C (PKC) like genes have been cloned from C. trifolii. Biochemical inhibition of PKA prevents germination; biochemical inhibitors of PKC prevents appressorium differentiation. In order to analyze reversible phosphorylation as a regulatory mechanism, some ser.thr dephosphorylative events have also been analyzed. Type 2A and Type 2B (calcineurin) phosphatases have been identified and structurally and functionally analyzed in N. crassa during this project. Both phosphatases are essential for hyphal growth and maintenance of proper hyphal architecture. In addition, a first novel-type (PPT/PP5-like) ser/thr phosphatase has been identified in a filamentous fungus. The highly collaborative project has improved our understanding of a fundamental process in fungi, and has identified targets which can be used to develop new approaches for control of fungal plant pathogens as well as improve the performance of beneficial fungi in the field and in industry. In addition, the feasibility of molecular technology transfer in comparative mycology has been demonstrated.
3
Delmer, Deborah P., Douglas Johnson, and Alex Levine. The Role of Small Signal Transducing Gtpases in the Regulation of Cell Wall Deposition Patterns in Plants. United States Department of Agriculture, August 1995. http://dx.doi.org/10.32747/1995.7570571.bard.
Full textAbstract:
The combined research of the groups of Delmer, Levine and Johnson has led to a number of interesting findings with respect to the function of the small GTPase Rac in plants and also opened up new leads for future research. The results have shown: 1) The Rac13 protein undergoes geranylgeranlyation and is also translocated to the plasma membrane as found for Rac in mammals; 2) When cotton Rac13 is highly- expressed in yeast, it leads to an aberrant phenotype reminiscent of mutants impaired in actin function, supporting a role for Rac13 in cytoskeletal organization; 3) From our searches, there is no strong evidence that plants contain homologs of the related CDC42 genes found in yeast and mammals; 4) We have identified a rather unique Rac gene in Arabidopsis that has unusual extensions at both the N- and C-terminal portions of the protein; 5) New evidence was obtained that an oxidative burst characterized by substantial and sustained production of H202 occurs coincident with the onset of secondary wall synthesis in cotton fibers. Further work indicates that the H202 produced may be a signal for the onset of this phase of development and also strongly suggests that Rac plays an important role in signaling for event. Since the secondary walls of plants that contain high levels of lignin and cellulose are the major source of biomass on earth, understanding what signals control this process may well in the future have important implications for manipulating the timing and extent of secondary wall deposition. 6) When the cotton Rac13 promoter is fused to the reporter gene GUS, expression patterns in Arabidopsis indicate very strong and specific expression in developing trichomes and in developing xyelm. Since both of these cell types are engaged in secondary wall synthesis, this further supports a role for Rac in signaling for onset of this process. Since cotton fibers are anatomically defined as trichomes, these data may also be quite useful for future studies in which the trichomes of Arabidopsis may serve as a model for cotton fiber development; the Rac promoter can therefore be useful to drive expression of other genes proposed to affect fiber development and study the effects on the process; 7) The Rac promoter has also been shown to be the best so far tested for use in development of a system for transient transformation of developing cotton fibers, a technique that should have many applications in the field of cotton biotechnology; 8) One candidate protein that may interact with Rac13 to be characterized further in the future is a protein kinase that may be analogous to the PAK kinase that is known to interact with Rac in mammals.
4
Epel, Bernard, and Roger Beachy. Mechanisms of intra- and intercellular targeting and movement of tobacco mosaic virus. United States Department of Agriculture, November 2005. http://dx.doi.org/10.32747/2005.7695874.bard.
Full textAbstract:
To cause disease, plant viruses must replicate and spread locally and systemically within the host. Cell-to-cell virus spread is mediated by virus-encoded movement proteins (MPs), which modify the structure and function of plasmodesmata (Pd), trans-wall co-axial membranous tunnels that interconnect the cytoplasm of neighboring cells. Tobacco mosaic virus (TMV) employ a single MP for cell- cell spread and for which CP is not required. The PIs, Beachy (USA) and Epel (Israel) and co-workers, developed new tools and approaches for study of the mechanism of spread of TMV that lead to a partial identification and molecular characterization of the cellular machinery involved in the trafficking process. Original research objectives: Based on our data and those of others, we proposed a working model of plant viral spread. Our model stated that MPᵀᴹⱽ, an integral ER membrane protein with its C-terminus exposed to the cytoplasm (Reichel and Beachy, 1998), alters the Pd SEL, causes the Pd cytoplasmic annulus to dilate (Wolf et al., 1989), allowing ER to glide through Pd and that this gliding is cytoskeleton mediated. The model claimed that in absence of MP, the ER in Pd (the desmotubule) is stationary, i.e. does not move through the Pd. Based on this model we designed a series of experiments to test the following questions: -Does MP potentiate ER movement through the Pd? - In the presence of MP, is there communication between adjacent cells via ER lumen? -Does MP potentiate the movement of cytoskeletal elements cell to cell? -Is MP required for cell-to-cell movement of ER membranes between cells in sink tissue? -Is the binding in situ of MP to RNA specific to vRNA sequences or is it nonspecific as measured in vitro? And if specific: -What sequences of RNA are involved in binding to MP? And finally, what host proteins are associated with MP during intracellular targeting to various subcellular targets and what if any post-translational modifications occur to MP, other than phosphorylation (Kawakami et al., 1999)? Major conclusions, solutions and achievements. A new quantitative tool was developed to measure the "coefficient of conductivity" of Pd to cytoplasmic soluble proteins. Employing this tool, we measured changes in Pd conductivity in epidermal cells of sink and source leaves of wild-type and transgenic Nicotiana benthamiana (N. benthamiana) plants expressing MPᵀᴹⱽ incubated both in dark and light and at 16 and 25 ᵒC (Liarzi and Epel, 2005 (appendix 1). To test our model we measured the effect of the presence of MP on cell-to-cell spread of a cytoplasmic fluorescent probe, of two ER intrinsic membrane protein-probes and two ER lumen protein-probes fused to GFP. The effect of a mutant virus that is incapable of cell-to-cell spread on the spread of these probes was also determined. Our data shows that MP reduces SEL for cytoplasmic molecules, dilates the desmotubule allowing cell-cell diffusion of proteins via the desmotubule lumen and reduces the rate of spread of the ER membrane probes. Replicase was shown to enhance cell-cell spread. The data are not in support of the proposed model and have led us to propose a new model for virus cell-cell spread: this model proposes that MP, an integral ER membrane protein, forms a MP:vRNAER complex and that this ER-membrane complex diffuses in the lipid milieu of the ER into the desmotubule (the ER within the Pd), and spreads cell to cell by simple diffusion in the ER/desmotubule membrane; the driving force for spread is the chemical potential gradient between an infected cell and contingent non-infected neighbors. Our data also suggests that the virus replicase has a function in altering the Pd conductivity. Transgenic plant lines that express the MP gene of the Cg tobamovirus fused to YFP under the control the ecdysone receptor and methoxyfenocide ligand were generated by the Beachy group and the expression pattern and the timing and targeting patterns were determined. A vector expressing this MPs was also developed for use by the Epel lab . The transgenic lines are being used to identify and isolate host genes that are required for cell-to-cell movement of TMV/tobamoviruses. This line is now being grown and to be employed in proteomic studies which will commence November 2005. T-DNA insertion mutagenesis is being developed to identify and isolate host genes required for cell-to-cell movement of TMV.