Academic literature on the topic 'Ossicle'

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Journal articles on the topic "Ossicle"

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YAMANA, YUSUKE, TAKESHI HAYASHIBARA, MASAKI YAMAMOTO, and DAVIN H. E. SETIAMARGA. "First observation of the "double-faced X-framed cup ossicle" extracted from a deep sea holothurian in Japan." Zoosymposia 15, no. 1 (October 21, 2019): 203–11. http://dx.doi.org/10.11646/zoosymposia.15.1.21.

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A New type ossicle form, “double-faced x-framed cup ossicle” is discovered from the undescribed deep sea holothuroid. To give a definite view on the substantial qualities of this ossicle, a SEM observation on the ossicles and a DNA barcoding analysis are conducted. Although the most internal and external morphologies of the present species agree well with the characteristics of the family Cucumariidae Ludwig, 1894, the ossicles morphologies mostly does not agree with the congeners of Cucumariidae. On the other hand, our molecular study indicates a possibility that the specimens are not cucumariids, but belong to a sister group of Cucumariidae. In our present observation, some of the peri-oral ossicles show a very similar property with the small x-framed cup-shaped structures (which sometimes occurs in cucumariids). Therefore, the double-faced x-framed cup ossicle probably could be considered as the results of derivation from the x-body: in which four extra-arms developed on the bottom face of a cup ossicle, and finally these arms equipped with an extra-rim.
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Taylor, Lawrence H., Brian K. Hall, and David K. Cone. "Experimental infection of yellow perch (Perca flavescens) with Apophallus brevis (Digenea, Heterophyidae): parasite invasion, encystment, and ossicle development." Canadian Journal of Zoology 71, no. 9 (September 1, 1993): 1886–94. http://dx.doi.org/10.1139/z93-269.

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Yellow perch (Perca flavescens) were exposed to cercariae of Apophallus brevis collected from naturally infected snails and maintained for up to 63 d postinfection (PI). Histochemistry revealed that attachment, penetration, migration, and encystment were complete by 2 d PI. By 14 d PI, a precursor to a host ossicle capsule surrounded the encysted metacercaria. Between 14 and 63 d PI a calcified matrix aggregated in a specific developmental pattern of islets, crescent, band, then ring, within an equatorial band at the cyst–capsule interface. The result was an ossicle ring of calcified tissue separating two uncalcified-matrix poles. Ossicle rings thickened and advanced over the cyst, but did not seal it off completely, forming an intermediate ossicle 49 d PI with two polarized canals. Pigmentation of ossicles through the appearance of melanocytes was not consistent between infections of the same age. Scanning electron microscopy revealed two distinct regions within fully developed ossicles. Randomly distributed interstitial fibres and ovoid and tubular lacunae surrounded by perilacunar collars formed the inner cellular region. The interstitial fibres within the outer region formed acellular/lamellar bands.
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Queiroz, Kevin de, and David A. Good. "The Scleral Ossicles of Opisthocomus and Their Phylogenetic Significance." Auk 105, no. 1 (January 1, 1988): 29–35. http://dx.doi.org/10.1093/auk/105.1.29.

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Abstract Dried scleral rings of Opisthocomus, Galliformes, Cuculiformes, and other birds were examined to determine the pattern of ossicle overlap in Opisthocomus and its bearing on the phylogenetic relationships of this taxon. Although Opisthocomus shares a derived number of 12 scleral ossicles with cuculid Cuculiformes, the pattern of ossicle overlap differs. Nevertheless, fewer modifications are required to derive the number and pattern of ossicles in Opisthocomus from the conditions in cuculid or musophagid Cuculiformes than from the conditions in any galliform. Our findings also indicate that the scleral rings of birds, unlike those of lizards, often do not conserve overlap relations between adjacent ossicles during phylogeny.
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Smith, Kevin M., and Matt B. Welch. "Painful Os Intermetatarseum." Journal of the American Podiatric Medical Association 100, no. 3 (May 1, 2010): 213–15. http://dx.doi.org/10.7547/1000213.

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Accessory ossicles are usually benign radiographic findings. However, they may become clinically significant if they fracture or cause soft-tissue irritation. An os intermetatarseum is an uncommon ossicle found between the bases of the first and second metatarsals. This article reviews some of the theories relating to the development of this uncommon ossicle and describes its role as a possible etiology of metatarsus primus varus. (J Am Podiatr Med Assoc 100(3): 213–215, 2010)
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Dudda, Ravi, Sowmya Tumkur Rangaiah, M. Hanumantha Prasad, and Nagavara Kalegowda Balaji. "Correlation between degree of hearing loss and intraoperative findings in tubotympanic type of chronic suppurative otitis media." International Journal of Otorhinolaryngology and Head and Neck Surgery 4, no. 2 (February 23, 2018): 537. http://dx.doi.org/10.18203/issn.2454-5929.ijohns20180717.

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<p class="abstract"><strong>Background:</strong> The aim of tympanoplasty done for tubotympanic type of chronic suppurative otitis media (CSOM) should not only be to achieve a dry ear, but also to give hearing improvement to the patient. Aim of this study was to determine the correlation between size and site of tympanic membrane perforation with degree of hearing loss and correlation between ossicular chain status and degree of hearing loss on pure tone audiometry.</p><p class="abstract"><strong>Methods:</strong> Patients with tubotympanic CSOM with hearing loss upto 60 dBHL undergoing tympanoplasty were examined to know the site and size of tympanic membrane(TM) perforation. Intraoperative findings pertaining to middle ear and ossicles were noted. </p><p class="abstract"><strong>Results:</strong> Out of 52 patients of tubotympanic type of CSOM, hearing loss was least (31.18±7.46 dBHL) in small perforations of the TM and highest in subtotal perforations (48.74±7.83 dBHL) which was statistically significant. Hearing loss was significantly more in posterior perforation (46.61±7.02 dBHL) than in anterior perforation of TM (32.65±8.77 dBHL).<strong> </strong>There was a statistically significant difference in pure tone average hearing loss between intact ossicle group (32.87±9.77 dBHL)<strong> </strong>and eroded ossicle group (43.39±9.60dBHL). Difference in air bone gap was also significant between intact ossicle group (24.09±9.56 dB) and eroded ossicle group (31.02±9.83 dB). Multiple ossicles were eroded in nineteen patients with incus being the most commonly eroded ossicle.</p><p><strong>Conclusions:</strong> In this study, hearing loss increased with increased size of TM perforation and also with posterior perforation. Incus was found to be the most commonly eroded ossicle. Multiple ossicles were seen eroded most commonly when hearing loss was moderate. The surgeon will be better equipped to do ossiculoplasty in view of these preoperative findings and also to counsel the patient better about their expectation of hearing improvement following surgery. </p>
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Park, Chul Hyun, and JeongJin Park. "Effect of Modified Broström Procedure With Periosteal Flap Augmentation After Subfibular Ossicle Excision on Ankle Stability." Foot & Ankle International 40, no. 6 (March 13, 2019): 656–60. http://dx.doi.org/10.1177/1071100719837230.

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Background: The study evaluated the clinical and radiographic outcomes of the modified Broström procedure (MBP) with periosteal flap augmentation after large subfibular ossicle excision for chronic lateral ankle instability (CLAI). Methods: Twenty-two CLAI cases with a large ossicle (≥10 mm) were treated consecutively using the MBP with periosteal flap augmentation after ossicle excision. The mean follow-up duration was 20 months (12-33). For clinical assessment, the visual analog scale (VAS), American Orthopaedic Foot & Ankle Society (AOFAS) score, and Karlsson-Peterson score were evaluated preoperatively and at the last follow-up. For radiographic assessment, the size of the ossicle was measured by magnetic resonance imaging, and the talar tilt angle and anterior talar displacement were measured preoperatively and at the last follow-up. Results: The VAS, AOFAS, and Karlsson-Peterson scores improved from 6.3, 68.7, and 56.9 preoperatively to 1.6, 94.5, and 92.4 at the last follow-up, respectively. The mean size of the ossicles was 14.8 mm (11-21 mm). The talar tilt angle and anterior talar displacement improved from 11.2 degrees and 8.3 mm preoperatively to 4.4 degrees and 3.9 mm at the last follow-up, respectively. Conclusion: MBP combined with periosteal flap augmentation after ossicle excision provided good clinical and radiographic outcomes in CLAI with a large ossicle. Level of Evidence: Level IV, case series.
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Comeau, Ariane, Cory D. Bishop, and Christopher B. Cameron. "Ossicle development of the crinoid Florometra serratissima through larval stages." Canadian Journal of Zoology 95, no. 3 (March 2017): 183–92. http://dx.doi.org/10.1139/cjz-2016-0195.

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Crinoids are the oldest living class of echinoderm and sister group to the remaining eleutherozoan clade and so are key to discussions on the evolution and development of the echinoderm skeleton. Here we present the intraspecific variation of ossicle development of the feather star Florometra serratissima (A.H. Clark, 1907) during its three larval stages: doliolaria, cystidean, and early pentacrinoid. To induce settlement, larvae were cultured on a sea table in glass bowls containing coralline algae. The soft tissues of 60 larvae were dissolved to isolate and to observe the ossicles with compound microscopy and scanning electron microscopy. From the late doliolaria stage to 56-day-old pentacrinoids, a total of four types of ossicle developed: oral plates, basal plates, columnar stalk ossicles, and an attachment disk. Occasionally, an additional plate was found under the basal plates, which may represent a vestigial infrabasal plate. The shape of the attachment disk was plastic to accommodate the substrate. Crinoid ossicle development is variable in size, shape, and number, and the timing of development is asynchronous; traits that may have contributed to the early rapid radiation and phenotypic disparity of echinoderms.
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Dairaghi, Jacob, Dan Rogozea, Rachel Cadle, Joseph Bustamante, Leni Moldovan, Horia I. Petrache, and Nicanor I. Moldovan. "3D Printing of Human Ossicle Models for the Biofabrication of Personalized Middle Ear Prostheses." Applied Sciences 12, no. 21 (October 31, 2022): 11015. http://dx.doi.org/10.3390/app122111015.

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The middle ear bones (‘ossicles’) may become severely damaged due to accidents or to diseases. In these situations, the most common current treatments include replacing them with cadaver-derived ossicles, using a metal (usually titanium) prosthesis, or introducing bridges made of biocompatible ceramics. Neither of these solutions is ideal, due to the difficulty in finding or producing shape-matching replacements. However, the advent of additive manufacturing applications to biomedical problems has created the possibility of 3D-printing anatomically correct, shape- and size-personalized ossicle prostheses. To demonstrate this concept, we generated and printed several models of ossicles, as solid, porous, or soft material structures. These models were first printed with a plottable calcium phosphate/hydroxyapatite paste by extrusion on a solid support or embedded in a Carbopol hydrogel bath, followed by temperature-induced hardening. We then also printed an ossicle model with this ceramic in a porous format, followed by loading and crosslinking an alginate hydrogel within the pores, which was validated by microCT imaging. Finally, ossicle models were printed using alginate as well as a cell-containing nanocellulose-based bioink, within the supporting hydrogel bath. In selected cases, the devised workflow and the printouts were tested for repeatability. In conclusion, we demonstrate that moving beyond simplistic geometric bridges to anatomically realistic constructs is possible by 3D printing with various biocompatible materials and hydrogels, thus opening the way towards the in vitro generation of personalized middle ear prostheses for implantation.
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Rupa, V., H. Krishnaswami, and A. Job. "Autograft ossicle selection in cholesteatomatous ear disease: histopathological considerations." Journal of Laryngology & Otology 111, no. 9 (September 1997): 807–9. http://dx.doi.org/10.1017/s0022215100138691.

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AbstractIn order to determine whether selection of autograft ossicles in cholesteatomatous ear disease should be based on upon their apperance under the surgical operating microscope, we studied the histopathological features of 113 such ossicles. We attempted to correlate the extent of erosion of the ossicle, as noted under the surgical operating microscope, with their histopathological apperance. There were 60 mallei and 53 incudes. Seventy-nine ossicles were eroded and 34 were intact. The commonest abnormality noted was erosion of the long process of the incus (75 per cent). Both intact and eroded ossicles had similar histological features. There was no evidence of intra-ossicular cholesteatoma. The results suggest that the extent of erosion of these ossicles as seen under the surgical operating microscope should in no wasy prejudice their use as autografts when required.
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Lee, Doo Jae, Dong Yeon Lee, and Jae Hee Lee. "Clinical significance and morphological analysis of the os subfibulare using radiologic assessment in patients with chronic lateral ankle instability." Foot & Ankle Orthopaedics 3, no. 3 (July 1, 2018): 2473011418S0030. http://dx.doi.org/10.1177/2473011418s00305.

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Category: Ankle Introduction/Purpose: Although os subfibulare has been associated to various clinical problems in patients with chronic lateral ankle instability (CLAI), there are a few studies on the analysis of morphological characteristics of os subfibulare. The purpose of this study is to analyze morphologic characteristics of the os subfibulare and to evaluate the clinical significance of the os subfibulare in patients with CLAI. Methods: Among 252 patients who visited our training hospital with the symptom of lateral ankle instability for more than 1 year after sustaining ankle injury, 71 patients with os subfibulare who underwent magnetic resonance imaging (MRI) of the ankle were included in this study. For each patient, the simple radiologic assessment was also performed. The shape and size of ossicles were measured on a sagittal MR images. The location of the subfibular ossicle was classified into 3 zones by relation with the attachment site of the anterior talofibular ligament. The talofibular impingement, in which ossicles impinged to the talar articular surface. Results: The most common shape of ossicles was oval, and the most common site of ossicles was ATFL attach site. 61% of patients showed talofibular joint impingement on axial MR images, whereas 28 cases showed normal congruency of the talofibular joint. Forty-eight cases in 71 patients with CLAI had an enlarged fibular shape instead of a contralateral fibula on simple radiographs. The age; sex; the shape, location, and size of the ossicle; talofibular articular impingement; and history of major trauma were associated with surgical treatment in statistical analysis. Conclusion: The morphological analysis of the os subfibulare revealed that the ossicle manifested radiographic differences based on its size, location, and morphology. Based on the findings of our study, we suggest it is crucial to understand the morphologeical characteristics of the os subfibulare in patients with CLAI and to establish the treatment plan accordingly.
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Dissertations / Theses on the topic "Ossicle"

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BARDELLI, DONATELLA. "SHWACHMAN-DIAMOND SYNDROME: FROM PATHOGENESIS TO DRUG TARGETING." Doctoral thesis, Università degli Studi di Milano-Bicocca, 2017. http://hdl.handle.net/10281/170787.

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La Sindrome di Shwachman (SDS) è una rara malattia genetica, autosomica recessiva, caratterizzata da insufficienza pancreatica, disfunzioni ematologiche, displasie scheletriche e disordini cognitivi. Nel 90% dei pazienti vengono riscontrate mutazioni a carico del gene SBDS. Similarmente ad altre sindromi midollari, i pazienti affetti da SDS hanno un aumentato rischio di insorgenza di mielodisplasie e leucemia, ma i meccanismi responsabili di questa predisposizione non sono ancora stati indagati in modo approfondito. Le cellule mesenchimali stromali (MSCs) vengono considerate fattori con un ruolo fondamentale nel mantenere e sostenere la plasticità e la sopravvivenza delle cellule staminali all’interno della nicchia midollare. Studi recenti hanno dimostrato inoltre come mutazioni specifiche a livello delle MSCs possono essere fattori sufficienti per disregolare i sottili equilibri omeostatici all’interno della nicchia e dare inizio ad un processo di trasformazione neoplastica. Il nostro gruppo ha dimostrato che MSCs derivate da pazienti affetti da SDS erano comparabili a quelli di donatori sani per quanto riguarda le loro caratteristiche in vitro (marcatori di superficie, capacità di differenziare in diversi lineages, abilità nel sostenere la vitalità di cellule CD34). La gene expression analysis condotta su 16 SDS-MSCs in realtà mostra come queste cellule avessero un pattern di espressione genica differente da quello delle mesenchimali di donatori sani, suggerendo come le mesenchimali SDS potessero avere un ruolo nei disordini ematologici riscontrati nella malattia. In questo studio abbiamo aumentato la corte di pazienti e, avvalendoci di un modello in vivo, abbiamo studiato il possibile coinvolgimento delle MSCs nei disordini ematopoietici. Il nostro modello prevedeva l’impianto sottocutaneo in topi immunocompromessi di pellet cartilaginei derivanti da MSCs da donatori sani e pazienti stimolate per 21 giorni con un particolare medium di differenziamento. Dopo 60 giorni, gli animali sono stati sacrificati e gli ossicoli recuperati per l’analisi istologica. Dai nostri dati emerge come, al termine del periodo sperimentale, solo i pellet derivati da MSCs di donatore sano siano stati in grado di formare una nicchia midollare completa, con presenza di trabecole ossee, adipociti e cellule ematopoietiche murine. Di contro, nessuno dei pellet derivati da paziente è stato ritrovato vascolarizzato o colonizzato da cellule ematopoietiche. L’analisi a time point precoci ci ha permesso di individuare dei difetti nel processo differenziativo dei pellet derivati da pazienti, che non mostravano riassorbimento cartilagineo, né deposizione di matrice ossea o processi di vascolarizzazione. Questo dato ci suggerisce come nel nostro modello le mesenchimali da paziente mostrino difetti nel loro processo differenziativo e di conseguenza possano essere coinvolte anche nei disordini ematologici a carico del midollo. Nella seconda parte del nostro studio abbiamo testato un farmaco su cellule ematologiche e non ematologiche di paziente. Questo farmaco agisce sulle nonsense stop codon mutation, una delle mutazioni più diffuse nei pazienti SDS a carico del gene SBDS, consentendo il read-through della mutazione non senso e quindi la produzione di una proteina completa. I nostri risultati hanno mostrato l’azione positiva di questo farmaco in diverse linee cellulari (linfoblastoidi, mesenchimali e mononucleate da midollo), restorando la produzione della proteina. Inoltre, il trattamento con questo farmaco ha anche prodotto miglioramenti a livello funzionale nelle cellule mononucleate. In particolare queste cellule, in seguito al trattamento, hanno mostrato un significativo aumento nella capacità di dare colonie CFU-GM. Questo risultato ha forti conseguenze a livello clinico poiché, non avendo mostrato effetti tossici, questo farmaco potrebbe essere proposto per la cura dei disordini ematologici in questi pazienti.
Shwachman-Diamond Syndrome (SDS) is a rare autosomal recessive disease, characterized by exocrine pancreatic disorder, hematological aberrancies, bone marrow failure and cognitive impairment. In 90% of patients the SBDS gene is found mutated. Similar to other marrow failure syndromes, SDS patients have an increased risk for developing myelodysplastic syndrome and AML. To date, the mechanisms underlying the bone marrow failure in SDS patients are not fully understood. Microenvironment constituents and in particular mesenchymal stromal cells (MSCs) are considered the pivotal organizers for the generation, maintenance and plasticity of the hematopoietic stem cell niche. Recent studies show that specific changes in MSCs may be sufficient to initiate a complex phenotype of disordered homeostasis with similarities to myelodysplasia. We have demonstrated that MSCs obtained from SDS patients were comparable in vitro to HD but gene expression analysis of 16 SDS-MSCs showed that these cells had a specific gene expression signature compared to HD. These results suggest that it is possible that MSCs could be involved in the pathogenesis of the SDS marrow disorders. We increased our patients cohort and investigated whether SDS-MSCs were able to sustain malignant evolution using an innovative scaffold-free in vivo system based on the ex vivo generation of semi-cartilaginous pellets (SCPs) from human MSCs. We obtained SCPs stimulating MSCs for 21 days with a specific differentiating medium and a complete and correct formation of cartilaginous tissues both in HD and SDS samples. These SCPs were transplanted heterotopically into subcutaneous tissue of immunocompromised mice. After 60 days, we sacrificed mice and collected ossicles. We found that in 90% of cases, HD were able to recreate the hematopoietic microenvironment, with the establishment of a complete marrow niche, while none of the transplanted SDS-SCPs was able to recreate the hematopoietic microenvironment, revealing a defect in these differentiating process. The second part of our study was focused on testing a specific drug able to act on nonsense stop codon mutation, one of the most diffuse alterations in SDS patients, linked to risk of developing myelodysplastic syndrome. We successfully obtained restoration of SBDS protein in different cell lineages deriving from patients (Lymphoblastoids, MSCs, mononuclear cells from bone marrow). Protein restoration was also accompanied in some cases with an improvement of functionality. In particular, mononuclear cells from bone marrow treated with drug showed an increase in their ability to form colonies when cultured in a specific assay. This represents a powerful result, due to the potential clinical consequences related to possible therapeutic strategy. Indeed, SDS patients in future could take advantage of this drug to ameliorate their hematological defects and abolish other symptoms.
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Fyfe, D. M. "An analysis of the development of the scleral ossicle system in the chick embryo." Thesis, University of Aberdeen, 1986. http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.379211.

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Павленко, Ольга Вячеславівна. "Методи визначення акустичних характеристик та підбору протезів кісточок середнього вуха людини." Master's thesis, Київ, 2018. https://ela.kpi.ua/handle/123456789/25485.

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Магістерська дисертація: загальний обсяг 108 с., основна частина 102 с. 15 табл., 22 рис., 37 джерел. Магістерська дисертація присвячена висвітленню перспективних методів визначення акустичних характеристик та підбору протезів кісточок середнього вуха людини. Стрімкий розвиток сучасних технологій зумовлює нові виклики як для здоров’я людини, так і до осучаснення існуючих методів та технологій його покращення. Це стосується і оторилогічних захворювань, а проблема освоєння і вдосконалення тимпанопластики зумовлює актуальність даного дослілження. Метою магістерської дисертації є дослідити проблему вибору матеріалу імплантатів (протезів) на основі формули середнього вуха людини в нормі. Відповідно до мети роботи, визначено основні завдання дослідження: 1. Дослідити фізичні передумови та принципи вимірювання імпедансу середнього вуха людини. 2. Описати теоретично і підтвердити експериментально формулу середнього вуха людини в нормі. 3. Проаналізувати історію розвитку тимпанопластики, її методи, матеріали та їх акустичні характеристики. 4. Обгрунтувати вибір матеріалів імплантатів (протезів) для заміни слухових кісточок із застосуванням моделі середнього вуха. Об'єктом дослідження є процес трансформації енергії слуховим трактом людини. Предметом дослідження виступають слухові протези для заміни слухових кісточок. Методи дослідження. В роботі використано математичну модель середнього вуха людини в нормі, побудовану на основі методу електромеханічних аналогій. За допомогою методів неруйнівного контролю було визначено акустичні характеристики матеріалів імплантатів (протезів), розроблено алгоритм підбору матеріалів імплантатів (протезів), оснований на формулі середнього вуха людини. Практичне значення одержаних результатів. Отримані результати вимірювання виміру твердості та жорсткості протезів підтверджують вірність і практичну користь даної методики та уможливлює його подальше впровадження в медичних закладах.
Master's thesis: pages, total – 108, main body – 102; 15 tables, 22figures, 37 references. This master's thesis investigates prospective techniques for determining acoustic characteristics and the middle ear ossicles prosthetics selection. The rapid development of modern technologies leads to new challenges both for human health and for the modernization of existing techniques and methods for its improvement. This also applies to otorhinolaryngological diseases, and the issue of mastering and improving tympanoplasty determines the relevance of this study. The purpose of this master's thesis is to study the problem of selecting the material for implants (prostheses) based on the formula of the middle ear in the norm. In accordance with the purpose of the work, the main objectives of the study are defined: 1. To study the physical preconditions and principles of measuring the impedance of human’s middle ear. 2. To Describe theoretically and confirm experimentally the formula of the middle ear in the norm. 3. To analyze the history of the development of tympanoplasty, its methods, materials, and their acoustic characteristics. 4. To substantiate the choice of materials for implants (prostheses) to replace auditory ossicles using the model of the middle ear. The object of research is the process of energy transformation by the human’s auditory tract. The subject of the study is the auditory prostheses that replace auditory ossicles. Research methods. The mathematical model of the human’s middle in norm is used in this paper and is based on the method of electromechanical analogies. With the help of non-destructive testing techniques, acoustic characteristics of implant materials (prostheses) were determined, an algorithm based on the human’s formula of the middle ear to select materials for implants (prostheses) was developed. The practical value of the results. The obtained results of measurements of hardness and rigidity of prostheses confirm the fidelity and practical utility of this methodology and allow its further implementation in medical institutions.
Магистерская диссертация посвящена освещению перспективных методов определения акустических характеристик и подбора протезов косточек среднего уха человека. Стремительное развитие современных технологий обусловливает новые вызовы как для здоровья человека, так и к осовременивания существующих методов и технологий его улучшение. Это касается и оторилогичних заболеваний, а проблема освоения и совершенствования тимпанопластике обуславливает актуальность данного дослилження. Целью магистерской диссертации является исследовать проблему выбора материала имплантатов (протезов) на основе формулы среднего уха человека в норме. В целях работы, определены основные задачи исследования: 1. Исследовать физические предпосылки и принципы измерения импеданса среднего уха человека. 2. Описать теоретически и подтвердить экспериментально формулу среднего уха человека в норме. 3. Проанализировать историю развития тимпанопластике, ее методы, материалы и их акустические характеристики. 4. Обосновать выбор материалов имплантатов (протезов) для замены слуховых косточек с применением модели среднего уха. Объектом исследования является процесс трансформации энергии слуховым трактом человека. Предметом исследования выступают слуховые протезы для замены слуховых косточек. Методы исследования. В работе использованы математическую модель среднего уха человека в норме, построенную на основе метода электромеханических аналогий. С помощью методов неразрушающего контроля были определены акустические характеристики материалов имплантатов (протезов), разработан алгоритм подбора материалов имплантатов (протезов), основанный на формуле среднего уха человека. Практическое значение полученных результатов. полученные результаты измерения измерения твердости и жесткости протезов подтверждают верность и практическую пользу данной методики и делает его дальнейшее внедрение в медицинских учреждениях.
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Pozzobon, Anna <1992&gt. "Sintesi di ossime mediante idrogenazione." Master's Degree Thesis, Università Ca' Foscari Venezia, 2020. http://hdl.handle.net/10579/16904.

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Le ossime sono composti molto importanti per molti usi a livello industriale, da additivi per le vernici a farmaci e pesticidi. Tuttavia la più rilevante è la cicloesanoneossima dalla quale mediante riarrangiamento di beckman si ottiene il caprolattame a sua volta usato per la sintesi di nylon-6. Lo studio dell'idrogenazione di diversi nitrocomposti aromatici ha mostrato che essi si idrogenano alle ammine corrispondenti con consecutiva ossimazione. I catalizzatori utilizzati sono a base di palladio, in particolare si è usato il catalizzatore di palladio supportato su carbone, le temperature si aggirano tra i 50 e i 60°C con pressioni di circa 10 bar di idrogeno.
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Leskovar, T., Julia Beaumont, N. Lisic, and S. McGalliard. "Auditory ossicles: a potential biomarker for maternal and infant health in utero." Taylor and Francis, 2019. http://hdl.handle.net/10454/17235.

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Yes
Background: Carbon (δ13C) and nitrogen (δ15N) isotope ratios of collagen from teeth and bone are used to study human nutrition and health. As bones are constantly remodelling throughout life, isotopic values of bone collagen represent an average of several years. In contrast, human teeth do not remodel and their primary dentine contains only the isotopic data from the time of formation. In contrast to all other bones, human auditory ossicles also appear not to remodel. As they develop in utero and finish formation in the first 2 years of life, their collagen should also represent isotopic values of these two relatively short periods. Aim: By comparing δ13C and δ15N data from ossicles and incremental dentine, this study aims to investigate how two developmental periods of the ossicles, in utero and the first 2 years of life, reflect in collagen obtained from the ossicles. Subject and methods: Ossicle and tooth samples of 12 individuals aged 0.5 ± 0.4 years to 13 ± 1 years from the nineteenth century St. Peter’s burial ground in Blackburn were collected and processed to obtain bulk bone and incremental dentine collagen which was measured for δ13C and δ15N. Results: Averaged δ13C and δ15N of ossicles are lower when compared to every age group except after 3 years of age. Average offset between ossicles and dentine of different groups ranges from 0.4–0.9‰ for δ13C and from 0.3–0.9‰ for δ15N, with highest counterbalance at birth and after the first 5 months after birth. Conclusions: There appears to be a systematic offset between the dentine and ossicle data. It seems that the second phase of development does not influence the isotopic values of collagen significantly and the data we are obtaining from ossicles represents the in utero period.
Research grant from The Society for the Study of Human Biology.
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LeNoir, James. "Post-Glacial Sedimentation in Ossipee Lake, New Hampshire:." Thesis, Boston College, 2019. http://hdl.handle.net/2345/bc-ir:108650.

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Thesis advisor: Noah P. Snyder
Land cover and climate changes, attributed to natural and anthropogenic forcings, cause deviations in geomorphic processes that act to deliver sediment from watersheds to lakes. In New England, contradictory evidence exists as to the influence of deforestation associated with EuroAmerican settlement and major flood events on watershed erosion rates over the past ~250 years. Through combining sediment core analysis from Ossipee Lake, New Hampshire with geomorphic analysis of the Ossipee Lake watershed, this study quantifies Holocene through Anthropocene watershed erosion rates, and assesses variations in rates in relation to short-term historic events such as major storm events or deforestation, and long-term variations related to natural climate variability and post-glacial landscape evolution. An 8.63 m core was collected and spans the entire period from deglaciation to present. Bulk composition and age-depth modeling, utilizing both short-lived radioisotopes and radiocarbon dating, are used to quantify changes in deposition and inferred erosion rates over time. Additional insight on sedimentary processes is provided by measurements of magnetic susceptibility and bulk geochemistry. Lake-sediment data suggests clastic sediment mass accumulation rates vary between 0.0032 to 0.5870 g/cm2/yr, with deposits of increased terrestrially derived sediment focused between ~8500 to 7800, ~6500 to 2500, and 1600 cal yr BP to present. Geomorphic analysis is used to identify regions within the watershed that act to deliver sediment to Ossipee Lake. Potential sources of sediment supply include loose, unconsolidated proglacial deposits near Ossipee Lake that transition to primarily till in upland areas. Calculated bed shear stress along rivers highlights areas in the watershed capable of transporting sediment and areas that can serve as traps thus limiting sediment delivery to Ossipee Lake
Thesis (MS) — Boston College, 2019
Submitted to: Boston College. Graduate School of Arts and Sciences
Discipline: Earth and Environmental Sciences
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Cheng, Zizhi. "Communication System over Gnu Radio and OSSIE." Thesis, University of North Texas, 2011. https://digital.library.unt.edu/ark:/67531/metadc103299/.

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GNU Radio and OSSIE (Open-Source SCA (Software communication architecture) Implementation-Embedded) are two open source software toolkits for SDR (Software Defined Radio) developments, both of them can be supported by USRP (Universal Software Radio Peripheral). In order to compare the performance of these two toolkits, an FM receiver over GNU Radio and OSSIE are tested in my thesis, test results are showed in Chapter 4 and Chapter 5. Results showed that the FM receiver over GNU Radio has better performance, due to the OSSIE is lack of synchronization between USRP interface and the modulation /demodulation components. Based on this, the SISO (Single Input Single Output) communication system over GNU Radio is designed to transmit and receive sound or image files between two USRP equipped with RFX2400 transceiver at 2.45G frequency. Now, GNU Radio and OSSIE are widely used for academic research, but the future work based on GNU Radio and OSSIE can be designed to support MIMO, sensor network, and real time users etc.
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Hainey, MacKenna. "Behavior and Functional Morphology of Respiration in the Basket Star, Gorgonocephalus eucnemis and Two Brittle Stars in the Genus Ophiothrix." Thesis, University of Oregon, 2019. http://hdl.handle.net/1794/24233.

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Gorgonocephalus eucnemis, Ophiothrix suensonii and Ophiothrix spiculata are aerobic Echinoderms. Previous observations on the anatomy of these two genera state five pairs of radial shields and genital plates are responsible for regulating the position of the roof of the body disc and the flushing of water in and out of the bursae. Rates of bursal ventilation increase by an average 60-64% when the ophiuroid is exposed to an increase in food or a decrease in dissolved oxygen in Gorgonocephalus. When exposed to hypoxic oxygen concentrations O. suensonii and O. spiculata increased bursal-ventilation rates by (means of) 35% and 28%. Measurements of DO from inside and outside the bursae show that DO is being absorbed during bursal-ventilations. These findings suggest bursal ventilation is a means of respiration and increased rates of bursal-ventilation may help meet increased oxygen demands during feeding and some periods of hypoxia. This dissertation includes unpublished, co-authored material.
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Paone, Eduardo. "Open-Source SCA Implementation-EmbeddedandSoftware Communication Architecture : OSSIE and SCA Waveform Development." Thesis, KTH, Microelectronics and Information Technology, IMIT, 2010. http://urn.kb.se/resolve?urn=urn:nbn:se:kth:diva-24259.

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Software Defined Radios (SDRs) are redefining the current landscape of wireless communications in both military and commercial sectors. The rapidly evolving capabilities of digital electronics are making it possible to execute significant amounts of signal processing on general purpose processors ratherthan using special-purpose hardware.

As a consequence of the availability of SDR, applications can be used to implement flexible communication systems in an operating prototype within a very short time. However, the initial lack of standards and design rules leads to incompatibility problems when using products from different manufacturers. This problem is critical for the military and public safety sectors, for this reason the US Army was interested in SDR and carried out research into the specification of a common software infrastructure for SDR. This initiative started in the mid-1990s and evolved into the Software Communications Architecture (SCA).

SCA is a non-proprietary, open architecture framework that allows a designer to design interoperable and platform independent SDR applications. At the same time the SCA framework, by abstracting the radio communication system, speeds up waveform development because developers no longer have to worry about hardware details.

This thesis project uses OSSIE, an open source SCA implementation, to illustrate the process of developing a waveform. Today companies are exploiting open source solutions and investing money to evaluate and improve available technologies rather than developing their own solutions: OSSIE provides a working SCA framework without any license cost. OSSIE also provides some tools to develop SCA waveforms. Of course open source software comes with some limitations that a designer must take into account. Some of these limitations will be described for OSSIE (specifically the limited documentation and lack of libraries), along with some suggestions for how to reduce their impact.

This thesis project shows in detail the development process for SCA waveforms in OSSIE. These details are examined in the course of successfully implementing a target waveform to enable the reader to understand the advantagies and disadvantages of this technology and to facilitate more people using OSSIE to develop waveforms. Although a waveform was successfully implemented there were unexpected issues with regard to the actual behavior of the waveform when implemented on the hardware used for testing.


QC 20100831
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Carrick, Matthew. "Logical Representation of FPGAs and FPGA Circuits within the SCA." Thesis, Virginia Tech, 2009. http://hdl.handle.net/10919/33858.

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A very basic engineering tradeoff is performance versus flexibility and this design choice must be made when developing a software radio. Hardware devices such as General Purpose Processors (GPPs), Digital Signal Processors (DSPs), Field Programmable Gate Arrays (FPGAs) and Application Specific Integrated Circuits (ASICs) all provide a designer with choices along the performance versus flexibility spectrum. The designer must choose a combination of GPP, DSP, FPGA and ASIC devices to balance the needs of performance versus flexibility. The Software Communications Architecture (SCA) is a specification for a software radio architecture produced by the Joint Program Executive Office (JPEO) Joint Tactical Radio System (JTRS). The 2.2 revision of the SCA only implies support for GPPs, with no specified support for additional devices such as FPGAs. However, FPGA integration within the scope of the SCA is still possible. The integration of an additional processing hardware device other than a GPP requires the ability to logically represent the device within the Core Framework. This representation is implemented within the OSSIE Core Framework, an open source implementation of the SCA. The representation requires the support of multiple implementations of signal processing components within the framework, a simple component deployment model, and the abstraction of the FPGA interactions into a software component.
Master of Science
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Books on the topic "Ossicle"

1

Cornish Historical Society (Cornish, Me.), ed. The Ossipee Valley. Charleston, SC: Arcadia, 2005.

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Ars, B. Tympano-ossicular allograft tympanoplasty: A manual of techniques. Amsterdam: Kugler Publications, 1993.

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Crawford, Ken. Ossie the otter. Hagerstown, MD: Autumn House Pub., 2009.

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Crawford, Ken. Ossie the otter. Hagerstown, MD: Autumn House Pub., 2009.

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Ossie the otter. Hagerstown, MD: Autumn House, 2009.

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Roberts, Richard P. Ossipee, New Hampshire, vital records, 1887-2001. Bowie, Md: Heritage Books, Inc., 2002.

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Watt, Judith. Ossie Clark, 1965-74. London: V&A Publications, 2003.

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Ossie Clark, 1965-74. London: V&A Publications, 2003.

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Ossie Clark, 1965-74. London: V&A Publications, 2005.

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Mabel, Hidden, ed. The lower Mount Washington Valley: Albany - Tamworth - Ossipee. Dover, N.H: Arcadia, 1996.

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Book chapters on the topic "Ossicle"

1

Pettway, Glenda J., and Laurie K. McCauley. "Ossicle and Vossicle Implant Model Systems." In Osteoporosis, 101–10. Totowa, NJ: Humana Press, 2008. http://dx.doi.org/10.1007/978-1-59745-104-8_7.

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Clack, Jennifer A., and Edgar Allin. "The Evolution of Single- and Multiple-Ossicle Ears in Fishes and Tetrapods." In Evolution of the Vertebrate Auditory System, 128–63. New York, NY: Springer New York, 2004. http://dx.doi.org/10.1007/978-1-4419-8957-4_5.

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Laudadio, P., L. Presutti, A. Ravaglioli, and R. Martinetti. "Research, Planning, and Design of Ear Ossicle Prototypes Based on Al2O3, Hydroxyapatite, and ZrO2." In Bioceramics and the Human Body, 486–90. Dordrecht: Springer Netherlands, 1992. http://dx.doi.org/10.1007/978-94-011-2896-4_67.

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Bettex-Galland, M., and E. Burger. "The Role of Osteoclasts in Demineralized Bone Powder Implants During the Angiogenetic Phase of Ossicle Formation." In Bone Transplantation, 216–17. Berlin, Heidelberg: Springer Berlin Heidelberg, 1989. http://dx.doi.org/10.1007/978-3-642-83571-1_39.

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Ishimoto, Shin-ichi. "Anomalies of the Auditory Ossicles." In Microtia and Atresia - Combined Approach by Plastic and Otologic Surgery, 44–48. Basel: S. KARGER AG, 2013. http://dx.doi.org/10.1159/000350602.

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Berwouts, Dieter, Laurent Goubau, Jeroen De Vil, Stefan Desmyter, and Jeroen Mertens. "Accessory Ossicles and Sesamoid Bones." In Clinical Atlas of Bone SPECT/CT, 1–12. Cham: Springer International Publishing, 2023. http://dx.doi.org/10.1007/978-3-030-32256-4_45-1.

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Gill, Glenda E. "Ossie and Ruby are One!" In No Surrender! No Retreat!, 151–72. New York: Palgrave Macmillan US, 2000. http://dx.doi.org/10.1007/978-1-137-05361-9_9.

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Masali, Melchiorre, Silvana Borgognini Tarli, and Margherita Maffei. "Auditory Ossicles and the Evolution of the Primate Ear: A Biomechanical Approach." In Language Origin: A Multidisciplinary Approach, 67–86. Dordrecht: Springer Netherlands, 1992. http://dx.doi.org/10.1007/978-94-017-2039-7_5.

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Beltrán-Fernández, Juan Alfonso, Adolfo López Liévano, Luis Héctor Hernández-Gómez, Guillermo Urriolagotia-Calderón, and Mauricio González Rebattú. "Numerical and Biomechanical Testings in Cadaveric Auditory Ossicles Using Computer Axial Tomography." In Advanced Structured Materials, 61–71. Cham: Springer International Publishing, 2015. http://dx.doi.org/10.1007/978-3-319-19470-7_5.

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"Meniscal Ossicle." In Diagnostic Imaging: Musculoskeletal Trauma, 795. Elsevier, 2016. http://dx.doi.org/10.1016/b978-0-323-39253-2.50188-9.

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Conference papers on the topic "Ossicle"

1

Jeong, Hwayeong, and Jung Kim. "Echinoderm Inspired Variable Stiffness Soft Actuator with Connected Ossicle Structure." In 2019 International Conference on Robotics and Automation (ICRA). IEEE, 2019. http://dx.doi.org/10.1109/icra.2019.8793545.

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Djinovic, Z., M. Tomic, R. Pavelka, G. Sprinzl, and H. Traxler. "Measurement of the human cadaver ossicle vibration amplitude by fiber-optic interferometry." In 2020 43rd International Convention on Information, Communication and Electronic Technology (MIPRO). IEEE, 2020. http://dx.doi.org/10.23919/mipro48935.2020.9245426.

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MIYASHITA, TAKENORI, HIROSHI HOSHIKAWA, TERUSHIGE MORI, SEIKO FUJIWARA, and NOZOMU MORI. "COMPARISON IN POSTOPERATIVE HEARING BETWEEN THE OSSICULAR RECONSTRUCTION USING THE AUTOLOGOUS CARTILAGE AND OSSICLE." In Proceedings of the 3rd Symposium. WORLD SCIENTIFIC, 2004. http://dx.doi.org/10.1142/9789812703019_0033.

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Deheyn, Dimitri D., Michael C. Allen, and Evelien De Meulenaere. "On the biophotonic properties of brittlestar ossicles." In SPIE OPTO, edited by Christopher E. Tabor, François Kajzar, Toshikuni Kaino, and Yasuhiro Koike. SPIE, 2015. http://dx.doi.org/10.1117/12.2084665.

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PARK, KEEHYUN, JUN-HO LEE, MIN JUNG CHO, YE YEON WON, MYONG HYUN BAEK, and Keehyun Park. "THREE-DIMENSIONAL MICRO-CT IMAGES FOR HUMAN OSSICLES." In Proceedings of the 3rd Symposium. WORLD SCIENTIFIC, 2004. http://dx.doi.org/10.1142/9789812703019_0038.

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Sain, Colby E., Nicholas S. Smith, and Colin D. Sumrall. "COMPARING MORPHOLOGICAL DIFFERENCES IN MISSISSIPPIAN OPHIUROID ARM OSSICLES." In GSA Annual Meeting in Phoenix, Arizona, USA - 2019. Geological Society of America, 2019. http://dx.doi.org/10.1130/abs/2019am-338584.

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Snyder, Jason. "OSSIE." In the 43rd ACM technical symposium. New York, New York, USA: ACM Press, 2012. http://dx.doi.org/10.1145/2157136.2157397.

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Prendergast, Patrick J., Henry J. Rice, and Alexander W. Blayney. "A Finite Element Analysis of a Healthy Middle-Ear and a Middle-Ear Reconstructed With Prostheses." In ASME 1999 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 1999. http://dx.doi.org/10.1115/imece1999-0469.

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Abstract:
Abstract The human car is a complex biomechanical arrangement of bones and soft-tissues. To sense a sound, the pressure wave enters the ear canal (a curved tube) and is transformed as it travels towards the tympanic membrane (or ear drum). The tympanic membrane vibrates causing motion of the three bones of the middle-ear: the malleus, incus, and stapes (commonly called the hammer, anvil, and stirrup). The stapes motion stimulates the perilymph fluid of the inner-ear leading to an electrical pulse to the brain allowing us to perceive sounds. The there bones (called the ossicles) are suspended from the surrounding bone by various ligaments. Replacement of the ossicles with a prosthesis is a common surgical procedure, though it is not entirely satisfactory because the prosthesis can loosen or even extrude out from the middle-ear. In this study, we have developed an FE model of the healthy middle-ear and compared its vibro-acoustic response with the middle-ear reconstructed with two types of prosthesis — a partial ossicular replacement prosthesis (PORP) and a total ossicular replacement prosthesis (TORP).
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Stock, Stuart R., Konstantin I. Ignatiev, Arthur Veis, Francesco De Carlo, and J. D. Almer. "Micro-CT of sea urchin ossicles supplemented with microbeam diffraction." In Optical Science and Technology, the SPIE 49th Annual Meeting, edited by Ulrich Bonse. SPIE, 2004. http://dx.doi.org/10.1117/12.558070.

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10

Freeman, Rebecca L., Benjamin Dattilo, David L. Meyer, James R. Thomka, Samuel Sheray, and Joanna Stebing. "“PHOSPHATIZATION” OF ECHINODERM OSSICLES: INSIGHTS FROM ORDOVICIAN AND MODERN ENVIRONMENTS." In GSA Annual Meeting in Phoenix, Arizona, USA - 2019. Geological Society of America, 2019. http://dx.doi.org/10.1130/abs/2019am-340352.

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Reports on the topic "Ossicle"

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Geohydrology and water quality of stratified-drift aquifers in the Saco and Ossipee River basins, east-central New Hampshire. US Geological Survey, 1995. http://dx.doi.org/10.3133/wri944182.

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