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Relevant bibliographies by topics / Orthopedic implants – Strength of materials / Dissertations / Theses

Dissertations / Theses on the topic 'Orthopedic implants – Strength of materials'

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Published: 10 December 2022

Last updated: 28 January 2023

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1

Tirunagari, Prashanthi. "Nanomechanical characterization of femoral head materials." Diss., Columbia, Mo. : University of Missouri-Columbia, 2006. http://hdl.handle.net/10355/5906.

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Thesis (M.S.)--University of Missouri-Columbia, 2006.
The entire dissertation/thesis text is included in the research.pdf file; the official abstract appears in the short.pdf file (which also appears in the research.pdf); a non-technical general description, or public abstract, appears in the public.pdf file. Title from title screen of research.pdf file (viewed on August 30, 1981) Includes bibliographical references.

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2

Cipa, Esra. "Surface Modifications of Orthopedic Implants for Improved Performance." University of Akron / OhioLINK, 2015. http://rave.ohiolink.edu/etdc/view?acc_num=akron1454680174.

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3

Bell, Bryan Frederick Jr. "Functionally graded, multilayer diamondlike carbon-hydroxyapatite nanocomposite coatings for orthopedic implants." Thesis, Georgia Institute of Technology, 2004. http://hdl.handle.net/1853/7962.

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4

Lee, Goonhee. "Selective laser sintering of calcium phosphate materials for orthopedic implants /." Digital version accessible at:, 1997. http://wwwlib.umi.com/cr/utexas/main.

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5

Bell, Bryan Frederick. "Functionally graded, multilayer diamondlike carbon-hydroxyapatite nanocomposite coatings for orthopedic implants." Available online, Georgia Institute of Technology, 2004:, 2004. http://etd.gatech.edu/theses/available/etd-06072004-131058/unrestricted/bell%5Fbryan%5Ff%5F200405%5Fms.pdf.

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6

Wong, Kai-lun, and 黄棨麟. "Strontium-substituted hydroxyapatite reinforced polyetheretherketone biomaterials in orthopaedic implants." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2009. http://hub.hku.hk/bib/B42182505.

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7

Wong, Kai-lun. "Strontium-substituted hydroxyapatite reinforced polyetheretherketone biomaterials in orthopaedic implants." Click to view the E-thesis via HKUTO, 2009. http://sunzi.lib.hku.hk/hkuto/record/B42182505.

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8

Fang, Liming. "Processing of HA/UHMWPE for orthopaedic applications /." View abstract or full-text, 2003. http://library.ust.hk/cgi/db/thesis.pl?MECH%202003%20FANG.

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Thesis (M.Phil.)--Hong Kong University of Science and Technology, 2003.
Includes bibliographical references (leaves 128-138). Also available in electronic version. Access restricted to campus users.

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9

Flanigan, Kyle Yusef. "Synthesis of HAP nano rods and processing of nano-size ceramic reinforced poly (L) lactic acid composites /." Thesis, Connect to this title online; UW restricted, 2000. http://hdl.handle.net/1773/10616.

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10

Chang, Hsuan-chen. "Porous bioceramic and biomaterial for bone implants /." Digital version accessible at:, 2000. http://wwwlib.umi.com/cr/utexas/main.

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11

Wong, Hoi-man, and 黃凱文. "The development of magnesium-based materials for orthopaedic applications." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2011. http://hub.hku.hk/bib/B47869549.

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The currently used biomaterials for surgical implantation include stainless steel, titanium and its alloys. However, due to the non-degradability and the mismatch of the mechanical properties between these metallic implants and human bone, there maybe a long-term adverse effect of inflammation or stress shielding effect. This may lead to bone loss which brings with a higher risk of implant failure. To avoid this problem, implants made of biodegradable materials are the alternatives. Due to the poor mechanical properties of biodegradable polymer especially for load-bearing area, biodegradable metal is used instead. Magnesium is the potential candidate since it is degradable with mechanical properties similar to human bone whilst magnesium ion is an essential element to human bodies. With the advantages of using magnesium for implantations, it can be potentially used for fracture fixation implant and bone substitutes. However, its rapid degradation and release of hydrogen gas may inhibit its use. Hence, modification is required. In this project, plasma immersion ion implantation and deposition (PIII&D) using aluminium oxide as the plasma source was conducted on the magnesium alloys. The corrosion resistance properties of the plasma-treated magnesium alloy were found to display significant improvement in immersion test especially at early time points. The plasma-treated sample was compatible with osteoblasts. Cells attached and grew on the treated sample but not the untreated sample. The animal study showed consistent results with the cell study, and there was a significant increase in bone formation around the treated sample when compared to the untreated sample. The other potential application of magnesium is its usage as a bone substitute. Due to the limitations of autografts and allografts, synthetic bone substitutes are developed. The ideal bone substitutes should have similar properties to those found with autografts. However, no such bone substitutes presently exist; hence, a novel hybrid material is fabricated in this project through the addition of magnesium granules into a biodegradable polymer polycaprolactone (PCL). The immersion test showed that an apatite layer composed of magnesium, calcium, phosphate and hydroxide was formed on the hybrids but not on pure PCL, which suggested that the hybrids were osteoinductive and osteoconductive. The compression test showed that the mechanical properties were enhanced with the incorporation of magnesium granules into pure PCL and were still maintained after 2 months of immersion. Osteoblasts grew well on the PCL-Mg hybrids. The addition of smaller amounts of magnesium granules (0.1g PCL-Mg) resulted in higher ALP activity and up-regulation of different bone markers when compared to the pure PCL. Finally, the animal studies showed that more new bone formation was found around the 0.1g PCL-Mg hybrids especially at early time points, which suggested that the healing time could be shortened. In conclusion, fracture fixation implants and novel bone substitutes based on magnesium were developed in this project. The aluminium oxide coating was able to improve the corrosion resistance properties of magnesium alloy by suppressing the release of magnesium ions. The PCL-Mg hybrids were found to be biodegradable, biocompatible, osteoconductive, osteoinductive and mechanically matched to human bone properties.
published_or_final_version
Orthopaedics and Traumatology
Doctoral
Doctor of Philosophy

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12

Hassan, S. M. Mahmudul. "Development of Novel High Strength Composite Calcium Phosphate Cement for Orthopedic Applications." University of Toledo / OhioLINK, 2018. http://rave.ohiolink.edu/etdc/view?acc_num=toledo1533212629435654.

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13

Yeung, Che-yan, and 楊芷茵. "Antibacterial properties and biocompatibility of novel peptide incorporated titanium alloy biomaterials for orthopaedic implants." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2010. http://hdl.handle.net/10722/197133.

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14

Leung, Kit-ying. "Anti-bacteria plasma-treated metallic surface for orthopaedics use." Click to view the E-thesis via HKUTO, 2008. http://sunzi.lib.hku.hk/hkuto/record/B41633994.

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15

Lin, Hsin-Yi. "Short term observations of in vitro biocorrosion of two commonly used implant alloys." Diss., Mississippi State : Mississippi State University, 2002. http://library.msstate.edu/etd/show.asp?etd=etd-08202002-105908.

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16

Bedi, Rajwant Singh. "Anticorrosion and biocompatible Zeolite based coatings for tissue regeneration on metallic bioimplants." Diss., UC access only, 2009. http://proquest.umi.com/pqdweb?index=9&did=1800212961&SrchMode=2&sid=3&Fmt=2&VInst=PROD&VType=PQD&RQT=309&VName=PQD&TS=1270057484&clientId=48051.

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17

Leung, Kit-ying, and 梁潔瑩. "Anti-bacteria plasma-treated metallic surface for orthopaedics use." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2008. http://hub.hku.hk/bib/B41633994.

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18

Lui, So-ching, and 雷素青. "Surface bioactivity enhancement of polyetheretherketone (PEEK) by plasma immersion ion implantation." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2009. http://hub.hku.hk/bib/B43572340.

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19

Chong, Yu-wah, and 莊瑜華. "In vitro and in vivo study of plasma immersion ion implantation (PIII)treated polyetheretherketone (PEEK)." Thesis, The University of Hong Kong (Pokfulam, Hong Kong), 2013. http://hub.hku.hk/bib/B4985883X.

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Polyetheretherketone (PEEK), a polymer with mechanical strength comparable to human bone, is gaining popularity in the orthopedic field because it can potentially relieve the clinical complications, such as stress shielding effect and inevitable implantation failure, which are caused by the mismatch of the mechanical strength between the current metallic implants and the implantation sites. However, it is bio-inert and requires supplementary modification. Plasma immersion ion implantation (PIII) has been well documented that it is a good way to improve the bioactivity of a biomaterial. It is a method that introduces new elements to the biomaterial, generating bio-functional groups on the material surface without altering its mechanical properties. Hence, the aim of this study is to improve the bioactivity of PEEK by modifying its surface chemistry with the use of water (H2O) and ammonia (NH3) plasma immersion ion implantation (PIII) without altering its mechanical properties. After PIII treatment, a series of surface characterization tests that provide information about the surface properties, such as surface energy, roughness, surface chemical composition and crystallinity of PIII-treated PEEK were carried out. Results show that both H2O PIII and NH3 PIII-treated PEEK had significantly higher surface energy and roughness than untreated PEEK. There was also no significant change in the crystallinity of the PIII-treated PEEK, indicating that PIII treatment will not alter the mechanical properties of PEEK. Improvement in wetting properties of PEEK samples suggest the formation of polar functional groups on the PIII-treated PEEK materials, while the increased in surface roughness may be due to the energetic bombardments of plasma ions on the material surface. The in vitro bioactivity of plasma-treated PEEK was investigated and confirmed with hMSC-TERT. Initial cell attachment, cell spreading area, cell proliferation and differentiation were studied. Cell adhesion and cell spreading were enhanced on PIII-treated PEEK, and higher cell viability was observed on PIII-treated PEEK. Moreover, cell proliferation was promoted on early time point and cell differentiation was also enhanced particularly on day 7 by measuring the alkaline phosphatase activity. Therefore, H2O-PIII and NH3-PIII treatments were able to promote the bioactivity of PEEK samples.
published_or_final_version
Orthopaedics and Traumatology
Master
Master of Philosophy

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20

Lui, So-ching. "Surface bioactivity enhancement of polyetheretherketone (PEEK) by plasma immersion ion implantation." Click to view the E-thesis via HKUTO, 2009. http://sunzi.lib.hku.hk/hkuto/record/B43572340.

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21

Garrido, Luiz Fernando. "Avaliação do desempenho de implantes de polietileno e de fosfato tricalcio, recobertos por hidrogel, em defeitos osteocondrais no joelho de cães." [s.n.], 2007. http://repositorio.unicamp.br/jspui/handle/REPOSIP/313400.

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Orientador: William Dias Belangero
Dissertação (mestrado) - Universidade Estadual de Campinas, Faculdade de Ciencias Medicas
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Resumo: Este estudo teve como objetivo avaliar o desempenho in vivo, de implantes cilíndricos com altura e diâmetro de 5mm formados por cerâmica ß-tricálcio fosfato (ß-TCP) ou polietileno de ultra-alto peso molecular (PEUAPM) todos recobertos com hidrogel de poli (2-hidroxi etil metacrilato) - poli(metacrilato de metila-co-ácido acrílico) (75:25) (pHEMA/poli (MMA-co-AA)) para preencher defeitos osteocondrais nos joelhos direito e esquerdo de cães. Foram operados treze cães machos com peso entre 15 e 25 kg fornecidos pelo Canil do Centro Multi Institucional de Bioterismo da Unicamp, sem raça definida, em bom estado de nutrição, vacinados após período prévio de quarentena. Cinco cães foram utilizados como controle e oito foram seguidos por nove meses após a colocação dos implantes. Os implantes de cerâmica foram colocados no sulco troclear do joelho direito e os de polietileno no joelho esquerdo. Foram realizadas análises da superfície do implante macroscópica (in vivo e in vitro), mecânica e microscópica, com a finalidade de avaliar a formação de tecido sobre o implante, o seu desgaste, o se desempenho viscoelástico e a interface formada entre o implante e o tecido ósseo. Os implantes de cerâmica apresentaram desempenho inferior ao polimérico, em todos os critérios avaliados. Embora não tenha havido desgaste significativo na superfície do hidrogel os dois implantes estudados produziram abrasão na superfície da patela
Abstract: This study had the purpose of evaluating ¿in vivo¿ the performance of ß-TCP ceramic or extreme high molecular weight polyethylene cylindrical implants, with height and diameter of 5mm, all covered with poly(2-HEMA) ¿ poly(methyl methacrilate-co-acrilic acid) hydro gel (polyHEMA/poly(MMA-co-AA) (75:25) in order to fill in bone defects in both the right and left knees of dogs. Thirteen male dogs weighting between 15 and 25kg, supplied by UNICAMP¿s Centro Multi Institucional de Bioterismo, were operated. All the dogs were well nourished, vaccinated and the operation took place after a previous quarantine period. Five dogs were used as control and eight were followed for nine months after putting the implants. The ceramic implants were placed in the right knees and the polyethylene ones in the left knees. Macroscopic, mechanic and microscopic analyses of the implant surface, (both in vivo and in vitro) were performed, in order to evaluate the tissue formation on the implant, the wearing off of the implant, the viscoelastic performance and the interface between the implant and the bone tissue. The ceramic implants presented an inferior performance when compared to the polymeric ones, in all of the evaluated aspects. Although there was no significant degradation on the hydro gel surface, both studied implants produced erosion on the kneecap surface
Mestrado
Cirurgia
Mestre em Cirurgia

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22

Medhekar, Vinay Shantaram. "Modeling and simulation of oxidative degradation of Ultra-High Molecular Weight Polyethylene (UHMWPE)." Link to electronic thesis, 2001. http://www.wpi.edu/Pubs/ETD/Available/etd-0828101-135959.

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23

Pengmanivong, Douangsavanh Widchaya Kanchanavasita. "The tensile bond strength of odontosil silicone to a heat polymerizing acrylic resin by four primers /." Abstract, 2008. http://mulinet3.li.mahidol.ac.th/thesis/2551/cd419/4836014.pdf.

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24

Reyes, Catherine Diane. "Collagen- and Fibronectin-Mimetic Integrin-Specific Surfaces That Promote Osseointegration." Diss., Georgia Institute of Technology, 2006. http://hdl.handle.net/1853/11599.

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Cell adhesion to the extracellular matrix through cell-surface integrin receptors is essential to development, wound healing, and tissue remodeling and therefore represents a central theme in the design of bioactive surfaces that successfully interface with the body. This is especially significant in the areas of integrative implant coatings since adhesion triggers signals that regulate cell cycle progression and differentiation in multiple cellular systems. The interactions of osteoblasts with their surrounding extracellular matrix are essential for skeletal development and homeostasis and the maintenance of the mature osteoblastic phenotype. Our objective was to engineer integrin-specific bioactive surfaces that support osteoblastic differentiation and promote osseointegration by mimicking these interactions. We target two specific integrins essential to osteoblast differentiation the type I collagen receptor alpha2beta1 and the fibronectin receptor alpha5beta1. The central hypothesis of this project was that the controlled presentation of type I collagen and fibronectin binding domains onto well-defined substrates would result in integrin-specific bioadhesive surfaces that support osteoblastic differentiation, matrix mineralization, and osseointegration. We have demonstrated that these biomimetic peptides enhance bone formation and mechanical osseointegration on titanium implants in a rat tibia cortical bone model. We have also shown that the presentation of multiple integrin-binding ligands synergize to enhance intracellular signaling and proliferation. Finally, we demonstrate the advantage of the short biomimetic peptides over the native ECM proteins. This research is significant because it addresses current orthopaedic implant limitations by specifically targeting cellular responses that are critical to osteoblastic differentiation and bone formation. This biomolecular approach provides a versatile and robust strategy for developing bioactive surfaces that enhance bone repair and osseointegration of orthopaedic implants.

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25

MAEDA, NANCY T. "Avaliação da neoformação óssea em tíbia de coelhos utilizando cúpula de hidroxiapatita associada a diferentes biomateriais." reponame:Repositório Institucional do IPEN, 2013. http://repositorio.ipen.br:8080/xmlui/handle/123456789/10542.

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Dissertação (Mestrado)
IPEN/D
Instituto de Pesquisas Energeticas e Nucleares - IPEN-CNEN/SP

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26

Hávová, Mariana. "Kostní implantáty na bázi železa." Master's thesis, Vysoké učení technické v Brně. Fakulta elektrotechniky a komunikačních technologií, 2016. http://www.nusl.cz/ntk/nusl-254467.

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This thesis refers to Fe-based biodegradable materials and their potencial aplications in medicine, especially as temporary bone implants. This work generaly summaries aplications of biomaterial in medicine with more interest kept on biodegradable materials and their in-vivo corrosion. The experimental part refers to conduction of porous Fe-based materials with silica addition. The structure of prepared specimens is identified by EDX and XRD analysis. The imersion test and electrochemical studies were conducted to observe corrosion behaviour with respect to different concentration of silica. Potenciodynamic curves were obtained to determine corrosion potencial and corrosion current density of prepared samples.

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27

Impergre, Amandine. "Interactions entre CoCrMo et milieu cellulaire : De la corrosion à la tribocorrosion." Thesis, Lyon, 2019. http://www.theses.fr/2019LYSEI060.

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La durabilité à long terme des prothèses articulaires repose sur leur résistance vis-à-vis de la corrosion et leur comportement à l'usure. Quels que soient les matériaux utilisés, des produits de dégradation (ions métalliques et débris d’usure) se forment, du fait de la corrosivité des fluides corporels et de la biomécanique des articulations. Généralement, ces produits sont associés aux complications post-opératoires et en conséquence, leurs effets constituent des préoccupations cliniques critiques. A cet égard, la tribocorrosion est une considération sérieuse dans la performance des prothèses articulaires. Ce travail vise à contribuer à l'amélioration de la compréhension des mécanismes de dégradation d’un alliage de CoCrMo, utilisé en tant que prothèse articulaire, en appréhendant le couplage de charges mécaniques et l’activité cellulaire. Cette thèse a été entreprise selon une approche itérative, qui débute par l’étude du comportement électrochimique du milieu physiologique simulé, propice à la culture cellulaire (le RPMI-1640). L’alliage métallique et les cellules ont successivement été ajoutés au système d’étude. Les essais ont révélé que l'oxydation du CoCrMo est accélérée en présence d'espèces carbonées et de composés organiques, et que les cellules interviennent sur la libération d’ions métalliques. Un dispositif de biotribocorrosion a été développé dans le but d’évaluer l’influence des produits de dégradation sur le métabolisme cellulaire. Cette étude multidisciplinaire exhaustive a combiné des techniques expérimentales d’électrochimie, de biologie et de tribologie, afin de souligner l'importance de la chimie de surface du biomatériau sur sa résistance à la tribocorrosion et son caractère cytotoxique. Finalement, une méthodologie expérimentale a été proposée dans ce travail, en vue de mieux comprendre l’interaction entre les fluides physiologiques simulés et les biomatériaux
The long-term durability of joint replacements is based on their corrosion resistance and wear behavior. Whatever the materials used, degradation products (metal ions and wear debris) are formed due to the aggressiveness of body fluids and the biomechanics of the joints. Generally, these products are associated with post-operative complications and, as a result, their effects are critical clinical concerns. In this respect, tribocorrosion is a serious consideration in the performance of joint replacements. This work aims to contribute to the improvement of the understanding of the degradation mechanisms of a CoCrMo alloy, used as a joint prosthesis, by understanding the coupling of mechanical loads and cellular activity. This thesis has been structured according to a progressive approach, which begins with the study of the electrochemical behavior of a simulated physiological environment conducive to cell culture (RPMI-1640). Metal alloys and cells were successively added to the study system. The tests revealed that the oxidation of CoCrMo is accelerated in the presence of carbonaceous species and organic compounds, and that the cells are involved in the release of metal ions. A biotribocorrosion device has been developed to evaluate the influence of degradation products on cellular metabolism. This comprehensive multidisciplinary study combined experimental techniques from electrochemistry, biology and tribology to highlight the importance of biomaterial surface chemistry on tribocorrosion resistance and cytotoxicity. Finally, an experimental methodology was proposed in this work, in order to better understand the interaction between simulated physiological fluids and biomaterials

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