Academic literature on the topic 'Orthopaedic device development'

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Journal articles on the topic "Orthopaedic device development"

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Kennedy, Darragh G., Aoife M. O’Mahony, Eamonn P. Culligan, Caitriona M. O’Driscoll, and Katie B. Ryan. "Strategies to Mitigate and Treat Orthopaedic Device-Associated Infections." Antibiotics 11, no. 12 (December 15, 2022): 1822. http://dx.doi.org/10.3390/antibiotics11121822.

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Orthopaedic device implants play a crucial role in restoring functionality to patients suffering from debilitating musculoskeletal diseases or to those who have experienced traumatic injury. However, the surgical implantation of these devices carries a risk of infection, which represents a significant burden for patients and healthcare providers. This review delineates the pathogenesis of orthopaedic implant infections and the challenges that arise due to biofilm formation and the implications for treatment. It focuses on research advancements in the development of next-generation orthopaedic medical devices to mitigate against implant-related infections. Key considerations impacting the development of devices, which must often perform multiple biological and mechanical roles, are delineated. We review technologies designed to exert spatial and temporal control over antimicrobial presentation and the use of antimicrobial surfaces with intrinsic antibacterial activity. A range of measures to control bio-interfacial interactions including approaches that modify implant surface chemistry or topography to reduce the capacity of bacteria to colonise the surface, form biofilms and cause infections at the device interface and surrounding tissues are also reviewed.
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Szeverényi, Csenge, and Marcell Varga. "Orthopaedic relevance of baby carrying." Orvosi Hetilap 154, no. 30 (July 2013): 1172–79. http://dx.doi.org/10.1556/oh.2013.29673.

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Recently, various ways of carrying a baby have become popular again. Different methods and options of infant carrying are largely influenced by current fashion trends. The term of baby carrying refers to carrying the infant close to the caregiver’s body with special devices, which aid attachment parenting. The authors often face the question in the pediatric orthopedic clinic: what kind of carrying method to recommend to the parents. In this article the authors briefly present the different means of carrying devices and they review the literature regarding orthopedic consequences of baby carrying. For the healthy development of a child, position and correct support of the hips and the spine are essential, whereas the carrier’s spinal protection is also an important aspect. After reviewing the literature, the authors conclude that baby carrying with an adequate device has advantages from orthopaedic point of view. Orv. Hetil., 2013, 154, 1172–1179.
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Hofmann, G. O., F. D. Wagner, and T. Hackhofer. "Biodegradable polymer device in orthopaedic surgery — Development of new implant designs." Journal of Biomechanics 27, no. 6 (January 1994): 833. http://dx.doi.org/10.1016/0021-9290(94)91422-2.

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Scialla, Stefania, Giorgia Martuscelli, Francesco Nappi, Sanjeet Singh Avtaar Singh, Adelaide Iervolino, Domenico Larobina, Luigi Ambrosio, and Maria Grazia Raucci. "Trends in Managing Cardiac and Orthopaedic Device-Associated Infections by Using Therapeutic Biomaterials." Polymers 13, no. 10 (May 12, 2021): 1556. http://dx.doi.org/10.3390/polym13101556.

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Over the years, there has been an increasing number of cardiac and orthopaedic implanted medical devices, which has caused an increased incidence of device-associated infections. The surfaces of these indwelling devices are preferred sites for the development of biofilms that are potentially lethal for patients. Device-related infections form a large proportion of hospital-acquired infections and have a bearing on both morbidity and mortality. Treatment of these infections is limited to the use of systemic antibiotics with invasive revision surgeries, which had implications on healthcare burdens. The purpose of this review is to describe the main causes that lead to the onset of infection, highlighting both the biological and clinical pathophysiology. Both passive and active surface treatments have been used in the field of biomaterials to reduce the impact of these infections. This includes the use of antimicrobial peptides and ionic liquids in the preventive treatment of antibiotic-resistant biofilms. Thus far, multiple in vivo studies have shown efficacious effects against the antibiotic-resistant biofilm. However, this has yet to materialize in clinical medicine.
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Anderson, William D., Sydney L. M. Wilson, and David W. Holdsworth. "Development of a Wireless Telemetry Sensor Device to Measure Load and Deformation in Orthopaedic Applications." Sensors 20, no. 23 (November 27, 2020): 6772. http://dx.doi.org/10.3390/s20236772.

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Due to sensor size and supporting circuitry, in-vivo load and deformation measurements are currently restricted to applications within larger orthopaedic implants. The objective of this study is to repurpose a commercially available low-power, miniature, wireless, telemetric, tire-pressure sensor (FXTH87) to measure load and deformation for future use in orthopaedic and biomedical applications. The capacitive transducer membrane was modified, and compressive deformation was applied to the transducer to determine the sensor signal value and the internal resistive force. The sensor package was embedded within a deformable enclosure to illustrate potential applications of the sensor for monitoring load. To reach the maximum output signal value, sensors required compressive deformation of 350 ± 24 µm. The output signal value of the sensor was an effective predictor of the applied load on a calibrated plastic strain member, over a range of 35 N. The FXTH87 sensor can effectively sense and transmit load-induced deformations. The sensor does not have a limit on loads it can measure, as long as deformation resulting from the applied load does not exceed 350 µm. The proposed device presents a sensitive and precise means to monitor deformation and load within small-scale, deformable enclosures.
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Salie, Faatiema, Kylie de Jager, Carsten Dreher, and Tania S. Douglas. "The scientific base for orthopaedic device development in South Africa: spatial and sectoral evolution of knowledge development." Scientometrics 119, no. 1 (February 23, 2019): 31–54. http://dx.doi.org/10.1007/s11192-019-03041-y.

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Sirivisoot, Sirinrath, and Thomas J. Webster. "Nanotechnology Enabled In Situ Orthopaedic Sensors for Personalized Medicine." Advances in Science and Technology 86 (September 2012): 40–50. http://dx.doi.org/10.4028/www.scientific.net/ast.86.40.

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Although improvements have been made in implant design to increase bone formation and promote successful osseointegration using nanotechnology, the clinical diagnosis of early bone growth surrounding implants remains problematic. The development of a device allowing doctors to monitor the healing cascade and to diagnose potential infection or inflammation is necessary. Biological detection can be examined by the electrochemical analysis of electron transfer (or redox) reactions of extracellular matrix proteins involved in bone deposition and resorption. The use of nanomaterials as signal amplifiers in electrochemical sensors has greatly improved the sensitivity of detection. Nanotechnology-enabled electrochemical sensors that can be placed on the implant surface itself show promise as self-diagnosing devices in situ, possibly to detect new bone growth surrounding the implant and other cellular events to ensure implant success.
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Persaud-Sharma, Dharam, and Anthony McGoron. "Biodegradable Magnesium Alloys: A Review of Material Development and Applications." Journal of Biomimetics, Biomaterials and Tissue Engineering 12 (February 2012): 25–39. http://dx.doi.org/10.4028/www.scientific.net/jbbte.12.25.

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Magnesium Based Alloys Possess a Natural Ability to Biodegrade due to Corrosion when Placed within Aqueous Substances, which Is Promising for Cardiovascular and Orthopaedic Medical Device Applications. these Materials Can Serve as a Temporary Scaffold when Placed in Vivo, which Is Desirable for Treatments when Temporary Supportive Structures Are Required to Assist in the Wound Healing Process. the Nature of these Materials to Degrade Is Attributed to the High Oxidative Corrosion Rates of Magnesium. in this Review, a Summary Is Presented for Magnesium Material Development, Biocorrosion Characteristics, as Well as a Biological Translation for these Results.
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Bettoni, Elisa, Giorgio Ferriero, Hadeel Bakhsh, Elisabetta Bravini, Giuseppe Massazza, and Franco Franchignoni. "A systematic review of questionnaires to assess patient satisfaction with limb orthoses." Prosthetics and Orthotics International 40, no. 2 (November 26, 2014): 158–69. http://dx.doi.org/10.1177/0309364614556836.

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Background:Assessment of patient satisfaction with orthosis is a key point for clinical practice and research, requiring questionnaires with robust psychometric properties.Objectives:To identify which validated questionnaires are used to investigate patient satisfaction with orthosis in limb orthotics and to analyse (1) their main fields of clinical application, (2) the orthosis-related features analysed by the questionnaires and (3) the strength of their psychometric properties.Study design:Systematic review.Methods:A literature search using MEDLINE (PubMed), Cumulative Index to Nursing and Allied Health Literature (CINAHL) and Scopus databases for original articles published within the last 20 years was performed.Results:A total of 106 papers pertaining to various clinical fields were selected. The main features of patient satisfaction with orthosis analysed were as follows: aesthetic, ease in donning and doffing the device, time of orthotic use and comfort.Conclusion:Of the questionnaires used to investigate patient satisfaction with orthosis, only four are adequately validated for this purpose: two for generic orthotic use (Quebec User Evaluation of Satisfaction with assistive Technology 2.0 and Client Satisfaction with Device of Orthotics and Prosthetic Users’ Survey) and two for specific application with orthopaedic shoes (Questionnaire for the Usability Evaluation of orthopaedic shoes and Monitor Orthopaedic Shoes). Further development, refinement and validation of outcome measures in this field are warranted.Clinical relevanceGiven the importance of analysing patient satisfaction with orthosis (PSwO), appropriate instruments to assess outcome are needed. This article reviews the currently available instruments and reflects on how future studies could be focused on the development, refinement and validation of outcome measures in this field.
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Riva, Giuseppe. "Virtual Reality In Paraplegia: A Test Bed Applicationn." International Journal of Virtual Reality 5, no. 1 (January 1, 2001): 146–56. http://dx.doi.org/10.20870/ijvr.2001.5.1.2676.

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The paper presents an overview of the ergonomic/design issues of a VR-enhanced orthopaedic appliance to be used in rehabilitation of patients with Spinal Cord Injury. First, some design considerations are described and an outline of aims which the tool should pursue are given. Finally, the design issues are described focusing both on the development of a test-bed rehabilitation device and on the description of a preliminary study detailing the use of the device with a long-term SCI patient. The basis for this approach is that physical therapy and motivation are crucial for maintaining flexibility and muscle strength and for reorganizing the nervous system after SCIs.
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Dissertations / Theses on the topic "Orthopaedic device development"

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Salie, Faatiema. "Analysis of orthopaedic device development in South Africa: Mapping the landscape and understanding the drivers of knowledge development and knowledge diffusion through networks." Doctoral thesis, Faculty of Health Sciences, 2021. http://hdl.handle.net/11427/33951.

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An orthopaedic medical device refers to a part, implant, prosthetic or orthotic which is used to address damage to the body's musculoskeletal system, primarily by providing stability and mobility. Orthopaedic medical devices play a role in injury-related disorders, which have been highlighted as a key element of the quadruple burden of disease in South Africa. In this thesis, orthopaedic devices are conceptualised as a technological field and a technological innovation system (TIS) framework is applied to understand orthopaedic device development in South Africa. Knowledge development and knowledge diffusion are fundamental components of any innovation system. The thesis hypothesises that the functions “knowledge development” and “knowledge diffusion through networks” of the orthopaedic devices TIS are influenced by contextual factors. The objectives of the study are: to identify the actors who generate knowledge for orthopaedic device development and to characterise the relationships between them; to identify focus areas of orthopaedic device development; to provide insight into the drivers and barriers to knowledge development and diffusion in the TIS; and to identify the contextual factors that influence knowledge dynamics in the TIS. These objectives are investigated using social network analysis based on bibliometric data (scientific publications and patents), keyword networks, a review of institutions, and a set of case studies where the primary data source are interviews with actors. Actors producing knowledge were from the university, healthcare, industry and science council sectors, although science councils played a small role. International actors were shown to bring new ideas into the TIS. The networks were fragmented, illustrating that knowledge diffusion through the networks was limited. This was especially the case in the patent networks as many actors patent in isolation. The keyword networks highlighted unrealised collaboration potential between actors based on their common research interests. The case studies revealed features of cross-sector interaction for orthopaedic device development not evident from network analysis based on bibliometric data. Drivers of knowledge development and knowledge diffusion were: inter-sectoral collaboration; the availability of resources; the affordability of available devices; and the positive externalities of allied TISs. The main barrier to knowledge development and diffusion was in the form of barriers to intersectoral collaboration. These include unmatched expectations from partners in collaboration, different views on intellectual property ownership, and burdensome university administrative processes. The orthopaedic devices TIS was structurally coupled to the embedded TIS and sectoral contexts, and externally linked and structurally coupled to its political context. Knowledge development and diffusion was found to be positively enhanced by innovation in the additive manufacturing TIS, with shared structural elements and resources. Knowledge development and diffusion was influenced by sectoral dynamics of the university, healthcare and industry sectors. This thesis makes the following contributions. First, it applies the TIS framework to a new focus area, namely medical device development, in a developing country context. Second, it makes two unique methodological contributions: it presents an index to capture the extent of sectoral collaboration in a network; and it develops a method for determining the collaboration potential of actors in a network based on cognitive distance.
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Book chapters on the topic "Orthopaedic device development"

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Armstrong, Peter F., and Bryan Snyder. "The Cyclical Process of Medical Device Realization: Development, Implementation, and Quality Control." In Quality Improvement and Patient Safety in Orthopaedic Surgery, 159–70. Cham: Springer International Publishing, 2022. http://dx.doi.org/10.1007/978-3-031-07105-8_15.

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Conference papers on the topic "Orthopaedic device development"

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Tighe, John. "Soft Tissue Fixation and Implant Development: Marketing/Commercialization." In ASME 2009 4th Frontiers in Biomedical Devices Conference. ASMEDC, 2009. http://dx.doi.org/10.1115/biomed2009-83073.

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Marketing, Sales, and Commercialization: Marketing and sales of orthopaedic medical devices are two of the most challenging and costly aspects of a successful commercial product launch. Many companies have developed an innovative product, filed for patents, passed through regulatory hurdles, and yet ultimately failed because of an inadequate marketing and sales plan. Invariably product launches cost more money and take longer to get off the ground than most companies forecast.
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Plumlee, Kevin G., and Christian J. Schwartz. "UHMWPE Composites for Orthopaedic Applications: A New Paradigm." In ASME/STLE 2009 International Joint Tribology Conference. ASMEDC, 2009. http://dx.doi.org/10.1115/ijtc2009-15075.

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The authors investigated the viability of UHMWPE composites for use in orthopaedic bearing applications as an alternative to crosslinking. Two composite systems were used, both based on a UHMWPE matrix: PtZr quasicrystals and Zr particle fillers. Through wear testing and impact toughness measurement it was shown that these two fillers produced composites that had high wear resistance and more impact toughness than the crosslinked polymer. These results suggest that further investigation into the use of composites for implant bearing surfaces is warranted and that appropriate criteria for filler materials must be developed to spur development of longer-lasting devices.
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Supriadi, Sugeng, Rakha M. Radhana, Taufik Eko Hidayanto, Yudan Whulanza, Ali, Nanda Notario, and Rahyussalim. "Orthopaedic jack for scoliosis surgery purposes: Concept and design." In BIOMEDICAL ENGINEERING’S RECENT PROGRESS IN BIOMATERIALS, DRUGS DEVELOPMENT, AND MEDICAL DEVICES: Proceedings of the First International Symposium of Biomedical Engineering (ISBE 2016). Author(s), 2017. http://dx.doi.org/10.1063/1.4976802.

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El-Gizawy, Ahmed Sherif. "Integrated Computer-Aided Approach for Supporting Development of Biomedical Devices." In ASME 2013 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2013. http://dx.doi.org/10.1115/imece2013-62832.

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Both medicine and engineering disciplines use problem-solving techniques to address different needs. The solutions often require an understanding of complex system behavior, identification of important system factors, and prediction of the outcome prior to application. This paper presents an introduction to integrated computer-aided approach to support developments in the field of biomedical devices, particularly for those used with orthopaedic surgery applications. The modern design process is first introduced as a road map to establish design that is robust, cost and time effective in order to satisfy the needs of the medical community. The coverage includes methods such as: function abstraction and decomposition, quality function deployment (QFD), case-based design (CBD) methodology, and risk management in design of orthopedic implants.
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Gupta, Ranjan. "Shoulder Arthroplasty: Current State of Affairs and Future Directions." In ASME 2009 4th Frontiers in Biomedical Devices Conference. ASMEDC, 2009. http://dx.doi.org/10.1115/biomed2009-83070.

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Shoulder arthroplasty is a reliable procedure used to treat glenohumeral arthritis thanks to the efforts of many orthopaedic surgeons and design engineers over the past thirty years. Surgeons such Drs. Charles Neer and Robert Cofield were instrumental to making clinical observations that were effectively translated into improving implant design and clinical outcomes. Yet, there remains much room for further growth and development. With the increase numbers of shoulder arthroplasties performed, new observations and problems have been recognized that remain unanswered.
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Tampieri, A., M. Sandri, T. D’Alessandro, M. Banobre-Lopez, and J. Rivas. "Innovative Biomimetic Hybrid Composites to Repair Multifunctional Anatomical Region." In ASME 2010 5th Frontiers in Biomedical Devices Conference. American Society of Mechanical Engineers, 2010. http://dx.doi.org/10.1115/biomed2010-32059.

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The development of biomimetic materials for osteochondral tissue substitution and repair can be the start for a revolution in the classical procedures of orthopaedic surgery. The persisting problems, linked to the absence of a complete functional recovery of the articulation and to the stabilization and protraction of the half-life of an articular prosthesis can be overcome by the new class of osteochondral substitutes. The characteristics of the artificial bone tissue are drastically different from those of the natural one and this is mainly due to the absence of the peculiar self-organizing interaction between apatite crystals and proteic matrix. At this purpose a biomimetic approach was used in which apatitic phases are directly nucleated on different macromolecular matrices, which act as template and induce peculiar physico-chemical features in the mineral phase to create a substitute for osteochondral lesions. In particular a biologically inspired approach was applied to nucleate bone-like hydroxyapatite (HA) nanocrystals on self-assembling collagen fibers. Biohybrid composite materials were obtained mimicking composition, structure and morphology of human osteochondral interfaces. [1–4]
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Chhabra, Nitin, David W. Nicholson, Larry Chew, Vimal Desai, and Simon Raab. "Finite Element Analysis of a Test Specimen for Adhesion of Bone Cement to Steel Implants." In ASME 2000 International Mechanical Engineering Congress and Exposition. American Society of Mechanical Engineers, 2000. http://dx.doi.org/10.1115/imece2000-2494.

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Abstract Stable fixation of an orthopaedic implant to bone cement is critical to long term stability and durability in joint replacement. Poor interfacial bonding between metal and bone cement also leads to the formation of a nonadherent fibrous capsule in both soft and hard tissues, which can result in micromovement at the implant-tissue interface and ultimate failure of the implant. It is believed that some of the difficulties encountered by metallic implant devices can be reduced by the use of bioactive materials on the implant surface. In the current study MMA/HEMA coating, at a nominal thickness of 2mm, is present at the bone cement-metal interface. The MMA/HEMA coating is in the development stage. The goals of the present study are to assess the strength of the adhesive bond under loading and to assess its effectiveness with respect to increasing the osteoconductivity of the implant.
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Ruhala, Laura, Dennis Beck, Richard Ruhala, Aaron Megal, and Megan Perry. "Development and Testing of an External Fixation Coupling for a Damage Control Orthopedic System." In 2017 Design of Medical Devices Conference. American Society of Mechanical Engineers, 2017. http://dx.doi.org/10.1115/dmd2017-3530.

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Seligson [1] describes how Hoffmann and Jaquet, a medical doctor and an engineer, respectively, developed the original Hoffmann fixator as a tool to stabilize human fractures with minimal invasiveness. Whether being utilized in mass trauma injury situations such as the 2010 Haitian earthquake, within our emerging geriatric population, or in veterinary applications, external fixation is widely used [1–4]. In this investigation, a rod-to-wire coupling, shown in Figure 1, and hereafter referred to as the R2W clamp, has been designed and validation tested for Stryker Orthopaedic’s Hoffmann II (HII) External Fixation System. As the name implies, this clamp has the purpose of connecting 8mm rods to 1.5mm or 2mm Kirschner (k-) wires or olive wires to stabilize bony fragments in the lower extremity, thus expediting healing in a trauma case. This paper summarizes the results of the validation tests conducted on prototype clamps. This clamp effectively allows placement of a wire to further stabilize a frame [3] by allowing wire placement without the addition of an intermediate ring, as shown in Figure 2. The wire could be added to any configuration with two parallel rods extending in plane with the bone. As shown in Figure 3, the R2W clamp can be positioned “outboard” with the rod between it and the bone, or “inboard” between the rod and the bone, allowing the surgeon geometric flexibility. The use of two k-wires is recommended to stabilize each bone fragment [5]. One of the goals of the validation testing was to determine the effectiveness and functional safety of the clamp as related to surgically applied k-wire tensions of either 50 kg or 100 kg. Since it is feasible that surgeons may tighten, loosen, then retighten the clamp while positioning it during surgery, the effects of clamp retightenings on the performance of the R2W clamp were also evaluated [4].
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