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Books on the topic 'Organ transplantation; Immunosuppression'

Author: Grafiati
Published: 4 June 2021
Last updated: 8 February 2022

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1

Gruber, Scott A. Local immunosuppression of organ transplants. New York: Chapman & Hall, 1996.

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2

FK506 and organ transplantation. Austin: R.G. Landes, 1994.

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3

Oremus, Mark. Utility of monitoring mycophenolic acid in solid organ transplant patients. Rockville, MD: Agency for Healthcare Research and Quality, 2008.

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4

Taylor, Charles B. Immunosuppression: New research. New York: Nova Biomedical Books, 2009.

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5

Otley, Clark C. Skin disease in organ transplantation. New York: Cambridge University Press, 2008.

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6

Current trends in transplantation: Drug therapy and monitoring. Abbott Park: Abbott Laboratories, 2009.

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7

Transplantation dermatology. Basel: Karger, 2012.

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8

United States. Congress. Senate. Committee on Labor and Human Resources. Immunosuppressive Drug Therapy Act of 1986: Report together with additional views (to accompany S. 2536). [Washington, D.C.?: U.S. G.P.O., 1986.

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9

Pirsch, John. Transplantation drug manual. 5th ed. Austin, Tex: Landes Bioscience, 2007.

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10

Lum, Caliann T. Research advances in human transplantation. [Bethesda, Md.?]: General Clinical Research Centers Program, National Center for Research Resources, 1991.

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11

D, Simmons William, and Sollinger Hans, eds. Transplantation drug manual. 4th ed. Austin, Tex: Landes Bioscience, 2003.

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12

Pirsch, John. Transplantation drug manual. 5th ed. Austin, Tex: Landes Bioscience, 2007.

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13

United States. Congress. Senate. Committee on Labor and Human Resources. Immunosuppressive Drug Therapy Act of 1986: Report together with additional views (to accompany S. 2536). [Washington, D.C.?: U.S. G.P.O., 1986.

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14

Resources, United States Congress Senate Committee on Labor and Human. Immunosuppressive Drug Therapy Act of 1986: Report together with additional views (to accompany S. 2536). [Washington, D.C.?: U.S. G.P.O., 1986.

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15

Report to the secretary and the Congress on immunosuppressive therapies. [Washington, D.C.]: U.S. Dept. of Health & Human Services, Public Health Service, Health Resources and Services Administration, Office of Organ Transplantation, 1985.

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16

United States. Congress. Senate. Committee on Labor and Human Resources. Immunosuppressive Drug Therapy Act of 1986: Hearing before the Committee on Labor and Human Resources, United States Senate, Ninety-ninth Congress, second session, on S. 2536 ... June 11, 1986. Washington: U.S. G.P.O., 1986.

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17

Resources, United States Congress Senate Committee on Labor and Human. Immunosuppressive Drug Therapy Act of 1986: Hearing before the Committee on Labor and Human Resources, United States Senate, Ninety-ninth Congress, second session, on S. 2536 ... June 11, 1986. Washington: U.S. G.P.O., 1986.

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18

United States. Congress. Senate. Committee on Labor and Human Resources. Immunosuppressive Drug Therapy Act of 1986: Hearing before the Committee on Labor and Human Resources, United States Senate, Ninety-ninth Congress, second session, on S. 2536 ... June 11, 1986. Washington: U.S. G.P.O., 1986.

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19

1960-, Scholz Martin, ed. CMV-related immunopathology. Basel [Switzerland]: Karger, 1998.

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20

Current Immunosuppressive Therapy in Organ Transplantation. Nova Science Publishers, Incorporated, 2015.

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21

Transplantation '95: The outlook for transplantation towards 2000. London: Royal Society of Medicine Press, 1995.

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22

(Contributor), Estella Alonso, Vincent T. Armenti (Contributor), Sharon Bartosh (Contributor), Charles Canter (Contributor), Richard Chinnock (Contributor), Carlos Araya Pochet (Contributor), Mark Bellinger (Contributor), Jean Pierre Botha (Contributor), and Richard Fine (Editor), eds. Pediatric Solid Organ Transplantation. 2nd ed. Blackwell Publishing Limited, 2007.

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23

Transplantation '95 (International Congress & Symposium). Royal Society of Medicine Press Ltd, 1995.

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24

Lopes, Eurides, and Jennifer Husson. Solid Organ Transplantation in HIV-Infected Individuals. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780190493097.003.0025.

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End-organ disease has become a major cause of morbidity and mortality in HIV-infected patients due to increased life expectancy, increasing the demand for organ transplantation in these patients. The care of HIV-infected transplant recipients warrants a multidisciplinary team approach, including the transplant team, pharmacists, infectious disease specialists, nurses, and patients and their families. The immunosuppression of HIV-infected recipients post-transplant does not appear to further advance HIV disease. The post-transplant risk for HIV-infected recipients of opportunistic infections does not appear to be increased by immunosuppression. However, the overall rate of infections is high, and it is even higher in hepatitis C virus (HCV) co-infected transplant recipients. HIV/HCV co-infected recipients have worse outcomes compared to both liver and kidney HIV-infected recipients.
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25

Tacrolimus in organ transplantation: Prevention and treatment of allograft rejections. Lengerich: Pabst Science Publishers, 1998.

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26

Dietrich, Schmähl, Penn Israel, and Deutsches Krebsforschungszentrum Heidelberg, eds. Cancer in organ transplant recipients. Berlin: Springer-Verlag, 1991.

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27

Pneumocystis-Carinii-Pneumonie Bei Immunosuppression: Prophylaxe Und Therapie in Der Hamatologie, Onkologie Und Bei Organ Transplantation. Walter De Gruyter Inc, 1991.

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28

Kahan, Barry D. Cyclosporine: The 10 Year Experience. Appleton & Lange, 1995.

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29

Kahan, Barry D. Cyclosporine: Diagnosis and Management of Associated Renal Injury. Grune & Stratton, 1985.

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30

Kahan, Barry D. Cyclosporine: Pharmacological Aspects. Grune & Stratton, 1987.

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31

D, Kahan Barry, and International Congress on Cyclosporine (3rd : 1994 : Seville, Spain), eds. Cyclosporine: The ten-year experience. Norwalk, Conn: Appleton & Lange, 1994.

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32

Gardiner, Matthew D., and Neil R. Borley. Transplant surgery. Oxford University Press, 2012. http://dx.doi.org/10.1093/med/9780199204755.003.0014.

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This chapter begins by discussing the basic principles of immunology and transplant rejection and immunosuppression, before focusing on the key areas of knowledge, namely organ donation, renal transplantation, and transplantation of other organs. The chapter concludes with relevant case-based discussions.
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33

1968-, Oremus Mark, Zeidler Johannes, and United States. Agency for Healthcare Research and Quality., eds. Utility of monitoring mycophenolic acid in solid organ transplant patients. Rockville, MD: Agency for Healthcare Research and Quality, 2008.

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34

1968-, Oremus Mark, Zeidler Johannes, and United States. Agency for Healthcare Research and Quality., eds. Utility of monitoring mycophenolic acid in solid organ transplant patients. Rockville, MD: Agency for Healthcare Research and Quality, 2008.

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35

Utility of monitoring mycophenolic acid in solid organ transplant patients. Rockville, MD: Agency for Healthcare Research and Quality, 2008.

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36

(Editor), Nicholas L. Tilney, Terry B. Strom (Editor), and Leendert C. Paul (Editor), eds. Transplantation Biology: Cellular and Molecular Aspects. Lippincott Williams & Wilkins, 1996.

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37

L, Tilney Nicholas, Strom T. B, and Paul Leendert C, eds. Transplantation biology: Cellular and molecular aspects. Philadelphia: Lippincott-Raven, 1996.

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38

(Editor), M. H. Sayegh, and Giuseppe Remuzzi (Editor), eds. Current and Future Immunosuppressive Therapies Following Transplantation. Springer, 2001.

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39

Morris, Peter J., and Jeremy R. Chapman. The evolution of kidney transplantation. Edited by Jeremy R. Chapman. Oxford University Press, 2015. http://dx.doi.org/10.1093/med/9780199592548.003.0275.

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The history of kidney transplantation starts in 1902 with Ullman transplanting kidneys between dogs, and Carrel’s development of vascular anastomotic techniques. The developments in the 1950s in Boston, Paris, and the laboratories of Medawar and others demonstrated both proof of the principle and some of the barriers to clinical kidney transplantation. The 1960s laid the groundwork for organ preservation, immunosuppression, and histocompatibility leading to the creation of transplant units in many countries. In the 1970s, there was steady progress in understanding the immunology of allograft rejection and its suppression. The advent of azathioprine used with steroids in the early 1960s resulted in 1-year graft survival rates of around 60% and patient survival of 90% in good units. However, with the introduction of ciclosporin in the early 1980s, renal transplantation became an even more reliable renal replacement option as there was a dramatic reduction in the incidence of irreversible acute rejection. The 1990s saw the introduction of both better immunosuppression and better infection prophylaxis, which further improved patient outcomes. The first decade of the twenty-first century has been characterized by the promise of new technologies in many areas, only some of which have delivered clinical benefit. Molecular human leucocyte antigen (HLA) typing and detection of antibodies to HLA antigens, standardized immunosuppression and anti-infective prophylaxis, surveillance biopsy, and developing systems for increasing donation rates are delivering major benefits. Gene biomarkers, stem cell therapy, and tolerance protocols have yet to make an impact. This chapter describes the historical development of transplantation and how it has yielded the results delivered in clinical practice today.
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40

Kotton, Camille Nelson. Infection. Edited by Jeremy R. Chapman. Oxford University Press, 2018. http://dx.doi.org/10.1093/med/9780199592548.003.0284_update_001.

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The immunosuppression which makes organ transplantation possible increases the risk of infections, both ordinary and opportunistic. The accurate diagnosis and management of infection after organ transplantation reduces morbidity and improves survival. Infections can be acquired in the hospital (i.e. nosocomial infections), from the transplant itself, from the blood product donor, from reactivation of latent infection in the host or from community exposure. Although viral infections are the most common, bacterial, fungal, and parasitic infections are also seen. While the intensity of immunosuppression is at its highest for a year after solid organ transplant, most opportunistic infections occur in the first 6 months.
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41

Ginns, Leo C. Immunosuppression In Transplantation. Blackwell Publishing, 1999.

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42

Billioux, Alexander. Infections in the Transplant Patient. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780199976805.003.0056.

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Recipients of donor-derived tissues and organs are at particularly high risk of infection because of their unique combination of risk factors. Chronic illness results in more exposure to health care contexts in which pathogens—especially drug-resistant species—might be acquired. The transplant surgery itself compromises anatomical barriers to infection via indwelling venous and urinary catheters, endotracheal tubes, and surgical wounds. Donor-derived tissues and organs may harbor infectious pathogens undetected during rapid pre-transplant evaluations. The immunosuppression necessary to prevent rejection of donor tissues increases the risk of infection. In addition, each type of transplanted organ bears unique infectious risks. Many pathogens seen in post-transplant patients have unique clinical presentations. Infections in the transplant patient can vary depending on time from transplantation, the type of organ transplanted, and the primary manifestation of the infection.
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43

Remuzzi, Giuseppe. Current and Future Immunosuppressive Therapies Following Transplantation. Ingramcontent, 2012.

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44

1964-, Otley Clark C., ed. Skin disease in organ transplantation. Cambridge: Cambridge University Press, 2008.

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45

(Editor), Clark C. Otley, and Thomas Stasko (Editor), eds. Skin Disease in Organ Transplantation. Cambridge University Press, 2008.

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46

Ramsay, Michael A. E. Anaesthesia for transplant surgery. Edited by Philip M. Hopkins. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780199642045.003.0067.

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The provision of anaesthesia for organ transplantation requires a team of specialist anaesthetists who are available 24 hours a day. The cold and warm ischaemia times may have very deleterious effects on the graft. The team must have a basic understanding of the immune system and the strategies of immunosuppression therapy. The preoperative assessment of the patient requires an understanding of the cause and effects of the compromised organ that is to be replaced. The procedure in many instances will result in a reperfusion syndrome when the graft is revascularized and also an ischaemia–reperfusion injury. The understanding of these entities is essential as is the preparation and protocols to treat or ameliorate the effects of these syndromes if they occur. The preparation for many organ transplants includes invasive monitoring of haemodynamics, cardiac function, pulmonary function, and acid–base balance. Access for massive transfusion therapy and coagulation assessment is essential for many transplant procedures. The maintenance of body temperature and fluid balance may be challenging. The protection and monitoring of the function of major organs such as the brain, heart, lungs, and kidneys is essential but the homeostasis of endocrine function and electrolytes is also important. The provision of excellent anaesthesia is a key component of a successful transplant programme. A small team of highly trained professionals with extensive training and experience in transplant anaesthesia provide the best results.
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47

New immunosuppressive modalities and anti-rejection approaches in organ transplantation. Austin: R.G. Landes Co., 1994.

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48

Koehler, Philipp, and Oliver A. Cornely. Fungal infections in haemato-oncology. Edited by Christopher C. Kibbler, Richard Barton, Neil A. R. Gow, Susan Howell, Donna M. MacCallum, and Rohini J. Manuel. Oxford University Press, 2017. http://dx.doi.org/10.1093/med/9780198755388.003.0032.

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Invasive fungal infections on haemato-oncology wards present a major challenge. Patients at risk for invasive fungal infection usually have a compromised immune system due to bone marrow failure caused by underlying disease, prolonged neutropenia after intensive chemotherapy, or immunosuppression after haematopoietic stem cell transplantation to avoid graft-versus-host disease. Three major entities—invasive candidiasis, invasive aspergillosis, and mucormycosis—account for the majority of fungal infections. Here, we describe specific host and therapeutic factors predisposing to invasive fungal infection in the haemato-oncology setting. Clinical presentation is highly variable and dependent on the underlying pathogen, organ involvement, and site of infection. Diagnosis is mainly based on radiographic imaging combined with microbiological and histopathological work-up. Various prophylaxis and treatment strategies have been developed, and the evidence for these is discussed.
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49

Kulkarni, Kunal, James Harrison, Mohamed Baguneid, and Bernard Prendergast, eds. Transplantation. Oxford University Press, 2016. http://dx.doi.org/10.1093/med/9780198729426.003.0030.

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Organ transplantation is now a well-established therapy for patients with end-stage organ failure. Over the last 20 years, the results of transplantation have improved incrementally for many reasons, including better recipient selection, improved anaesthetic and surgical techniques, the introduction of more effective antiviral agents, and better post-transplant immunosuppressive management. The problem of early graft loss from acute rejection is now uncommon, and the main challenges today are chronic allograft rejection and the side effects of non-specific suppression of the immune response. Randomized clinical trials continue to inform and further improve clinical practice. Because transplantation today is largely successful, the traditional endpoints of 1-year patient and graft survival are no longer sufficient, and more sophisticated endpoints are needed that reflect graft function and quality of life after transplantation. This chapter brings together studies which recognize this need for clinical trials which improve practice and focus on more broadly defined endpoints.
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50

Penn, Israel. Malignant Tumors in Organ Transplant Recipients. Springer-Verlag, 2012.

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