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Journal articles on the topic 'Oral lichen planu'

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Author: Grafiati

Published: 14 March 2023

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1

Hasan Zeynalova, Jala, Gulnara Salam Mammedova, Gunel Mammad Sultanova, İrada Arif Mammedxanova, Sevda Tariyel Huseynova, and Shahla Rafael Yusubova. "TREATMENT OF ORAL LICHEN PLANUS LICHEN PLANUS WITH PHOTODYNAMIC THERAPY." NATURE AND SCIENCE 14, no. 09 (November 23, 2021): 10–13. http://dx.doi.org/10.36719/2707-1146/14/10-13.

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Ağız boşluğunda yastı dəmirovun meydana gəlməsi ilə bağlı irəli sürülən bir sıra nəzəriyyələrə baxmayaraq, bu növ allergiya polietioloji hesab olunur.Ağız boşluğunun qırmızı yastı dəmirovu bir insandan digərinə keçə bilməz. Xəstəlik immun sisteminin naməlum səbəblərdən ağızın selikli qişasında hüceyrələrin strukturunun pozulması nəticəsində baş verir. Simptomlar adətən müalicə olunur, lakin ağızda qırmızı yastı dəmirovu olan insanlar mütəmadi həkim konsultasiyasına ehtiyac duyurlar. Açar sözlər: ağız boşluğunun qırmızı yastı dəmirovu, fotodinamik terapiya, metilen abısı

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2

Koneru, Dr Jyothirmai, Dr Mallika Mahalakshmi P, and Dr Ravindra Naik. "Management of Oral lichen Planus – A Review." Indian Journal of Applied Research 3, no. 3 (October 1, 2011): 289–90. http://dx.doi.org/10.15373/2249555x/mar2013/95.

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3

Timková, S., J. Minčík, M. Riznič, E. Ďurovič, and A. Konečná. "Lichen planus of the Oral Mucosa." Česká stomatologie/Praktické zubní lékařství 118, no. 1 (March 1, 2018): 3–7. http://dx.doi.org/10.51479/cspzl.2018.015.

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4

Timková, S., J. Minčík, M. Riznič, E. Ďurovič, and A. Konečná. "Lichen planus of the Oral Mucosa." Česká stomatologie/Praktické zubní lékařství 118, no. 1 (March 1, 2018): 3–7. http://dx.doi.org/10.51479/cspzl.2018.015.

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5

Dermawan, I. G. N. Putra, and I. Nyoman Gede Juwita Putra. "MANAGEMENT OF ORAL LICHEN PLANUS TRIGGERED BY STRESS." Interdental Jurnal Kedokteran Gigi (IJKG) 17, no. 1 (June 22, 2021): 27–33. http://dx.doi.org/10.46862/interdental.v17i1.1949.

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Introduction: Oral lichen planus (OLP) is a mucocutaneous disorder that rarely occurs around us and only involves the layer of the stratified squamous epithelium. Oral lichen planus is more common in women aged 30-65 years. The etiology of this disorder is not yet known, but there are several predisposing factors that play a role, such as hepatitis C virus infection, food, drugs, malignancy, and psychological factors. Purpose: This case report aims to describe the treatment of stress-induced OLP. Case Report: A 46-year-old man presented with complaints of stinging on the inner right and left cheeks for one month ago. The patient admits that he has a lot of thoughts related to family problems. It is found that the lesion resembles a white streak with redness that forms in the intraoral area. Case management: The patient was given therapy in the form of topical corticosteroids and consulted to psychiatry and got improvement after 1 week of treatment. Discussion: The treatment of OLP lesions is a treatment that requires collaboration between the dentist, the patient and the patient's family. Corticosteroid therapy is the gold standard treatment given to people with OLP. Corticosteroids are widely used in medicine because of their strong effect and fast anti-inflammatory reaction. Corticosteroids are widely used for the management of inflammatory diseases. Besides supporting therapy in consultation with a psychologist or psychiatrist to deal with stress disorders. Conclusion: Treatment of OLP lesions is a complex treatment. Corticosteroid therapy, both topical and systemic, is the most appropriate therapy and the role of a psychologist or psychiatrist is needed in managing patient stress to increase the percentage of patient recovery.

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6

Janovská, M., and Š. Podzimek. "ORAL LICHEN PLANUS - CURRENT POINT OF VIEW." Česká stomatologie/Praktické zubní lékařství 119, no. 4 (December 1, 2019): 100–111. http://dx.doi.org/10.51479/cspzl.2019.026.

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7

Janovská, M., and Š. Podzimek. "ORAL LICHEN PLANUS - CURRENT POINT OF VIEW." Česká stomatologie/Praktické zubní lékařství 119, no. 4 (December 1, 2019): 100–111. http://dx.doi.org/10.51479/cspzl.2019.026.

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8

Padmapriya, N., and K. Karthikeyan. "Oral lichen planus with linear lichen planus: a rare association." International Journal of Research in Dermatology 5, no. 2 (April 26, 2019): 429. http://dx.doi.org/10.18203/issn.2455-4529.intjresdermatol20191776.

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<p class="abstract">Lichen planus (LP) is a papulosquamous disorder with both cutaneous and mucosal manifestation. Linear lichen planus is rare variant of lichen planus which occurs in the extremities. Oral lichen planus is another variant of lichen planus. Coexistence of linear lichen planus with oral lichen planus is rare and only one case has been reported before this case. A 35 year old female presented with hyperpigmented linear lesion in the leg and whitish plaques in the oral cavity. Biopsy of the skin lesions showed features of lichen planus. The patient was started on topical steroids and oral hydroxychloroquine. Patient responded to treatment.</p>

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9

Bradić-Vasić, Marija, Ana Pejčić, Milena Kostić, Ivan Minić, Radmila Obradović, and Ivana Stanković. "Lichen planus: Oral manifestations, differential diagnosis and treatment." Acta stomatologica Naissi 36, no. 81 (2020): 1980–94. http://dx.doi.org/10.5937/asn2081980b.

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Introduction: Some of the typical skin diseases, such as Pemphigus vulgaris, Pemphigoid mucosae oris, Erythema exudativum multiforme, Sclerodremia, Dermatitis herpetiformis-Duhring and Lichen planus, can cause swelling and irritation in mucous membranes of the oral cavity. Aim: The aim of the study was to precise diagnosis and treatment of oral Lichen planus manifestations. Methods: Analyzing the literature data and the experience of clinicians, the most common oral lichen planus manifestations were investigated. Results: This disease most commonly occurs in middle-aged patients (30-60 years) and is more common in women than in men. Oral Lichen planus is rarely seen in children. The disease presents in 0.5% to 2% of the population. Clinical history established the relation between oral Lichen planus and oral carcinoma, and therefore this disease should be considered a precancerous lesion. Conclusion: Dermatoses in the mouth are localized most often in the oral mucosa, both at the height of the occlusal line and in the mucous membrane of the retromolar area, but they can also occur in the mucous membranes of the tongue, the floor of the mouth and lips.

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10

Ion, Daniela I., and Jane F. Setterfield. "Oral Lichen Planus." Primary Dental Journal 5, no. 1 (February 2016): 40–44. http://dx.doi.org/10.1177/205016841600500104.

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Lichen planus (LP) is a relatively common autoimmune T-cell-mediated disease of unknown aetiology affecting the mucous membranes, skin and nails. Its prevalence varies between 0.5 and 2.2% of the population in epidemiological studies with a peak incidence in the 30–60 years range and with a female predominance of 2:1.1 Mucosal lichen planus tends to follow a chronic course with acute exacerbations. Spontaneous remission of oral lichen planus (OLP) is uncommon, and indeed mucosal LP may become worse with time. In contrast, cutaneous lichen planus may follow a milder clinical course though some variants may be severe such as those affecting the palms and soles and the scalp and the genital tract in females (vulvovaginal gingival LP) where scarring leads to significant complications. It is important to identify those cases that may be drug induced or be associated with a contact allergic or irritant reaction (lichenoid reaction) or the rarer oral presentation of discoid lupus erythematosus. There is a very small risk of malignancy (approximately 1:200 patients/year) associated with oral lichen planus; thus patients should be informed that long term monitoring via their general dental practitioner is appropriate. This review will focus on the clinical presentation and management of oral lichen planus.

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11

Belső, Nóra. "New therapeutic strategies of lichen ruber planus." Bőrgyógyászati és Venerológiai Szemle 97, no. 5 (October 29, 2021): 278–82. http://dx.doi.org/10.7188/bvsz.2021.97.5.7.

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Lichen ruber planus/lichen planus (LP), is a chronic immune-mediated inflammatory disease that affects the skin, oral mucosa, genital mucosa, scalp and nails. Planar, purple, polygonal, pruritic, papules and plaques appear on the flexor surfaces of the wrists, forearms and legs. Mucosal lesions are often lacy, reticular, white lines known as Wickham striae. Topical corticosteroids are the first-line therapy for all forms of LP, for severe, widespread LP systemic corticosteroids, acitretine, oral immunosuppressants or narrowband UVB therapy should be considered. Cutaneous LP may resolve spontaneously within one or two years, while mucosal LP may be more persistent and resistant to treatment.

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12

Sehalic, Meliha, N. Djordjevic, D. Marjanovic, D. Staletovic, Z. Arsic, and N. Mitic. "Oral lichen planus." Praxis medica 43, no. 3 (2014): 71–75. http://dx.doi.org/10.5937/pramed1403071s.

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13

Rajendran, R. "Oral lichen planus." Journal of Oral and Maxillofacial Pathology 9, no. 1 (2005): 3. http://dx.doi.org/10.4103/0973-029x.39050.

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14

N/A. "Oral Lichen Planus." Biological Therapies in Dentistry 18, no. 02 (2002): 001. http://dx.doi.org/10.2310/7040.2002.28203.

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15

Wright, J. "Oral lichen planus." British Dental Journal 197, no. 5 (September 2004): 224–25. http://dx.doi.org/10.1038/sj.bdj.4811634.

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16

Stoopler, E. T., and T. P. Sollecito. "Oral lichen planus." Canadian Medical Association Journal 184, no. 14 (April 2, 2012): E774. http://dx.doi.org/10.1503/cmaj.111825.

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17

Parashar, Pallavi. "Oral Lichen Planus." Otolaryngologic Clinics of North America 44, no. 1 (February 2011): 89–107. http://dx.doi.org/10.1016/j.otc.2010.09.004.

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18

Jungell, Peter. "Oral lichen planus." International Journal of Oral and Maxillofacial Surgery 20, no. 3 (June 1991): 129–35. http://dx.doi.org/10.1016/s0901-5027(05)80001-3.

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19

Sugerman, Philip B., Neil W. Savage, Xijing Zhou, Laurence J. Walsh, and Michael Bigby. "Oral lichen planus." Clinics in Dermatology 18, no. 5 (September 2000): 533–39. http://dx.doi.org/10.1016/s0738-081x(00)00142-5.

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20

Conklin, Robert J., and Bruce Blasberg. "Oral Lichen Planus." Dermatologic Clinics 5, no. 4 (October 1987): 663–73. http://dx.doi.org/10.1016/s0733-8635(18)30709-5.

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21

CHAINANI-WU, NITA, SOL SILVERMAN, FRANCINA LOZADA-NUR, PRISCILLA MAYER, and JESSICA J. WATSON. "Oral lichen planus." Journal of the American Dental Association 132, no. 7 (July 2001): 901–9. http://dx.doi.org/10.14219/jada.archive.2001.0302.

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22

Olson, Meredith A., Roy S. Rogers, and Alison J. Bruce. "Oral lichen planus." Clinics in Dermatology 34, no. 4 (July 2016): 495–504. http://dx.doi.org/10.1016/j.clindermatol.2016.02.023.

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23

Au, Justin, Dhaval Patel, and John H. Campbell. "Oral Lichen Planus." Oral and Maxillofacial Surgery Clinics of North America 25, no. 1 (February 2013): 93–100. http://dx.doi.org/10.1016/j.coms.2012.11.007.

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24

Greer, Robert O., HumL, John D. McDowell, and George Hoernig. "Oral Lichen Planus." Pathology Case Reviews 4, no. 1 (January 1999): 28–34. http://dx.doi.org/10.1097/00132583-199901000-00006.

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25

Allen, Carl M. "Oral Lichen Planus." Pathology Case Reviews 4, no. 1 (January 1999): 35–39. http://dx.doi.org/10.1097/00132583-199901000-00007.

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26

Thompson, Lester D. R. "Oral Lichen Planus." Ear, Nose & Throat Journal 91, no. 3 (March 2012): 102–4. http://dx.doi.org/10.1177/014556131209100306.

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27

Hamour, Amr F., Hagen Klieb, and Antoine Eskander. "Oral lichen planus." Canadian Medical Association Journal 192, no. 31 (August 3, 2020): E892. http://dx.doi.org/10.1503/cmaj.200309.

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28

Savin, J. A. "Oral lichen planus." BMJ 302, no. 6776 (March 9, 1991): 544–45. http://dx.doi.org/10.1136/bmj.302.6776.544.

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29

Jayachandran, S., K. Sarala, and Priyanka Khobre. "Oral Lichen Planus, 2 Varied Clinical Presentations and Its Therapeutic Intervention." Indian Journal of Dental Education 10, no. 1 (2017): 53–56. http://dx.doi.org/10.21088/ijde.0974.6099.10117.7.

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30

Markovská, N. "Diagnosis and Treatment Possibilities of Oral Lichen Planus." Česká stomatologie/Praktické zubní lékařství 113, no. 1 (March 1, 2013): 3–6. http://dx.doi.org/10.51479/cspzl.2013.031.

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31

Markovská, N. "Diagnosis and Treatment Possibilities of Oral Lichen Planus." Česká stomatologie/Praktické zubní lékařství 113, no. 1 (March 1, 2013): 3–6. http://dx.doi.org/10.51479/cspzl.2013.031.

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32

Mardani, Maryam, Hossein Mofidi, Ladan Dastgheib, Sara Ranjbar, and Nasrin Hamidizadeh. "Elevated Serum Interleukin-23 Levels in Patients with Oral and Cutaneous Lichen Planus." Mediators of Inflammation 2021 (July 12, 2021): 1–6. http://dx.doi.org/10.1155/2021/5578568.

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Lichen planus is considered a chronic inflammatory disease which affects different sites, such as the skin, mucous membranes, hair, and nails. Based on the evidence, a complex cytokine network plays a crucial role in lichen planus pathogenesis. The study was aimed at assessing the serum IL-23 levels in the patients with cutaneous and oral lichen planus compared to healthy controls. Method. The study included 30 cutaneous lichen planus patients, 20 oral lichen planus patients, and 33 control subjects. Five milliliters of peripheral blood was obtained from each patient, and the serum was separated. IL-23 levels were determined using the ELISA kit, and the data were analyzed using the Mann–Whitney test. Results. IL-23 levels in the patient serum with oral lichen planus ( P value ≤ 0.001) were significantly higher than in controls. Furthermore, there were significant differences in IL-23 serum levels in the patients with cutaneous lichen planus compared to the healthy controls ( P value ≤ 0.001). Moreover, IL-23 serum levels were statistically different between patients with cutaneous lichen planus and patients with oral lichen planus ( P value ≤ 0.001). Based on the mean concentration of interleukin-23, IL-23 levels were higher in the patients with oral lichen planus than in the patients with cutaneous lichen planus. Conclusions. Elevated serum IL-23 levels in the patients with oral lichen planus may indicate that IL-23 plays a crucial role in the pathogenesis of oral lichen planus. However, more research is needed with a larger sample size.

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33

Hu, Yuhan. "The relationship between serum vitamin D level with inflammatory markers and Total Antioxidant Capacity in Oral lichen planus." Cellular and Molecular Biology 67, no. 5 (February 4, 2022): 227–32. http://dx.doi.org/10.14715/cmb/2021.67.5.31.

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Inflammatory markers play an important role in the pathophysiology of patients with oral problems such as oral lichen planus. This study aimed to investigate the relationship between vitamin D levels and inflammatory markers and total antioxidants in people with oral lichen planus. In this case-control study, 131 patients with oral lichen planus (67 in the lichen planus group and 54 in the control group) were examined. 8 cc of blood was taken from all participants to assess blood factors, inflammatory markers and antioxidant levels. Data were analyzed using SPSS statistical software. The mean age of subjects was 42 years. Vitamin D3 levels in the lichen planus group were lower than in the control group, but this decrease was not statistically significant (P> 0.05). According to statistical findings in the lichen planus group, there was a significant relationship between vitamin D3 levels, inflammatory markers and cellular stress factors (P≤0.05). It is concluded that vitamin D3 in people with oral lichen planus can play an important role in the pathogenesis of oral disease and increase inflammation. Because patients with oral lichen planus are affected by various inflammatory factors, paying attention to vitamin D levels in these patients can be effective in reducing inflammation caused by lichen planus.

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34

Batsakis, John G., Karen R. Cleary, and Kyung-Ja Cho. "Lichen Planus and Lichenoid Lesions of the Oral Cavity." Annals of Otology, Rhinology & Laryngology 103, no. 6 (June 1994): 495–97. http://dx.doi.org/10.1177/000348949410300613.

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Lichen planus is a mucocutaneous disease of unknown cause that has its principal clinical manifestations in the skin and mucosa of the oral cavity. The natural history of the cutaneous form is one of spontaneous resolution over time, while oral lichen planus pursues a much more chronic course with a low order of resolution. Oral lichen planus must be distinguished from lichenoid lesions, including lichenoid dysplasia. Malignant change in oral lichen planus is rare and is prompted by carcinogenic cofactors. There is no increased risk of development of carcinoma in cutaneous lichen planus.

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35

Miranda, Andreina, Isabella Santos, Witórya Conceição, and Hellen Santos. "Manifestações clínicas e opções terapêuticas do líquen plano oral: uma revisão de literatura." Odontologia Clínico-Científica 20, no. 1 (2021): 55–61. http://dx.doi.org/10.25243/issn.1677-3888.v20i1p55-61.

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36

Акмалова, Г., G. Akmalova, С. Чуйкин, S. Chuykin, Г. Ронь, G. Ron, Н. Чернышева, et al. "The use of genetic markers in predicting of oral lichen planus development and recurrence." Actual problems in dentistry 12, no. 1 (March 25, 2016): 62–69. http://dx.doi.org/10.18481/2077-7566-2016-12-1-62-69.

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To reveal the association of the interleukin 8 (IL-8) gene with the development and progression of oral lichen planus (OLP) we performed RT-PCR analysis of rs4073 polymorphism in the IL-8 gene in 92 oral lichen planus patients and 163 healthy individuals of Russian ethnic origin from the Volga-Ural region of Russia. The investigation showed the importance of polymorphism rs4073 of IL-8 gene for oral lichen planus development. The disease was associated with genotype rs4073*T / T which was found to be the genetic marker of high risk for oral lichen planus development, and rs4073*A / T genotype — the genetic marker of low risk for erosive-ulcerous oral lichen planus form development (p=0.016, OR=0.40) and the disease recurrence (p=0.02, OR=0.33). The results obtained in the investigation make a significant contribution to understanding the structure of hereditary predisposition to oral lichen planus development.

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37

Анисимова, Ирина, Irina Anisimova, Лаура Симонян, and Laura Simonyan. "THE FREQUENCY OF COMBINATION OF ORAL LICHEN PLANUS WITH SOMATIC PATHOLOGY AND LOCAL UNFAVORABLE FACTORS OF THE ORAL CAVITY." Actual problems in dentistry 15, no. 1 (May 6, 2019): 16–22. http://dx.doi.org/10.18481/2077-7566-2019-15-1-16-22.

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Background. In this article, we studied the frequency of combination of oral lichen planus with somatic pathology. The analysis of the survey, testing of individuals with oral lichen planus, laboratory blood counts; personalized advisory opinions of the local therapists. The influence of local adverse factors was studied by analyzing the indicators of galvanic current and the oral hygiene index. Objectives ― to study the frequency of combination of lichen planus with somatic pathology, the level of psycho-emotional status of patients, the role of local adverse factors in the oral cavity. Methods. There were analyzed two groups of patients in the age of 24―65 years. The main group (numbered in 22 people), included patients with oral lichen planus and control group (numbered in 15 people) combined people without pathology of the oral mucosa. The main group was divided into two subgroups I (numbered in 11 people), combined patients with a typical form of oral lichen planus and subgroup II (numbered in 11 people) included patients with an erosive-ulcerative form of oral lichen planus. Clinical and laboratory examinations were conducted by a local therapist to identify somatic pathology. Filled in the “health questionnaire” and tested by the method of Zung. Determined the concentration of glucose in blood; blood pressure indicators; the level of hygiene and galvanic current. Results. Questioning showed that patients with oral lichen planus have somatic pathology. Testing according to Zung's method revealed psycho-emotional disorders. Clinical and laboratory examination by a therapist revealed 100 % somatic pathology, concentration of glucose in blood and blood pressure in most individuals exceeded WHO standards. Analysis of the hygiene index showed a low level of oral hygiene; analysis of galvanometry revealed the presence of galvanic current in the oral cavity. Conclusions. Among all patients with oral lichen planus somatic pathology was detected in 100 % of cases. Lichen planus proceeds against the background of psycho-emotional disorders. Local unfavorable factors of the oral cavity (low level of hygiene and galvanic current) aggravate the course of lichen planus, slow down the regeneration.

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38

Kumar, Amit, and Divya Kashyap. "Prevalence of oral lichen planus among north Indian population: a descriptive epidemiological study." EUREKA: Health Sciences, no. 3 (May 31, 2022): 17–21. http://dx.doi.org/10.21303/2504-5679.2022.002437.

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The aim: oral lichen planus is a chronic inflammatory disease affecting the oral mucous membrane. It can present in various clinical forms: reticular, papular, plaque-like, atrophic, erosive and bullous. Though the exact etiology is not certain - autoimmunity, trauma, stress, and habits are considered as etiological factors. Oral lichen planus has been classified as a premalignant lesion. The present study aims to describe the prevalence of oral lichen planus in a sample of north Indian population. Materials and methods: the present study was conducted in the outpatient department of Dentistry, GMC Badaun. The parameters recorded were age, gender and site affected. The data was collected and analysed. Results: a total of 6263 patients reported to the outpatient department of dentistry out of which 43 patients were diagnosed with oral lichen planus. The overall prevalence of oral lichen planus was found to be 0.69 %. The mean age of disease presentation was 37.5 years. A higher prevalence of oral lichen planus was reported in females compared to males with a ratio of 1:1.15. Most affected site was found to be buccal mucosa bilaterally (58.14 %). Conclusion: the present study estimated the overall prevalence of oral lichen planus as well as its distribution according to age, gender and site in north Indian population. This could contribute to the precise assessment of the disease for better policy making for better treatment and management of oral lichen planus.

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39

Generali, Joyce, and Dennis J. Cada. "Pimecrolimus: Lichen Planus (Oral)." Hospital Pharmacy 43, no. 2 (February 2008): 106–12. http://dx.doi.org/10.1310/hpj4302-106.

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40

Jontell, M. "US5 Oral lichen planus." Oral Diseases 12, s1 (September 2006): 4. http://dx.doi.org/10.1111/j.1601-0825.2006.01306_16.x.

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41

Stoopler, Eric T., Scarlet Charmelo-Silva, Mohammed Bindakhil, Faizan Alawi, and Thomas P. Sollecito. "Oral Lichen Planus Pemphigoides." American Journal of Dermatopathology 42, no. 6 (June 2020): 467–69. http://dx.doi.org/10.1097/dad.0000000000001585.

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42

Cox, Teresa, Jamie Woodhead, and Brenda L. Nelson. "Reticular Oral Lichen Planus." Head and Neck Pathology 14, no. 1 (November 2, 2018): 192–94. http://dx.doi.org/10.1007/s12105-018-0983-6.

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43

Samycia, Michael, and Andrew N. Lin. "Efficacy of Topical Calcineurin Inhibitors in Lichen Planus." Journal of Cutaneous Medicine and Surgery 16, no. 4 (July 2012): 221–29. http://dx.doi.org/10.1177/120347541201600403.

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Background: Topical calcineurin inhibitors have been studied in many skin disorders, including lichen planus. Objective: To evaluate published reports of the use of topical calcineurin inhibitors in lichen planus. Methods: We searched PubMed, Ovid/Cochrane, and Embase using the keywords “tacrolimus,” “pimecrolimus,” “topical calcineurin inhibitors,” and “lichen planus.” Results: We examined 5 double-blind studies, 1 investigator-blinded study, 10 open prospective studies, 6 retrospective studies, and 28 case reports evaluating tacrolimus or pimecrolimus for oral, vulvovaginal, and cutaneous lichen planus. Conclusions: Strong evidence (double-blind and open studies) supports the use of topical tacrolimus ointment in oral lichen planus, with efficacy at least equal to topical clobetasol propionate 0.05% ointment. Treatment of oral lichen planus with topical tacrolimus ointment can result in demonstrable blood tacrolimus levels, but without clinically significant adverse events. Strong evidence (double-blind and open studies) supports the use of topical pimecrolimus 1% cream in oral lichen planus, with efficacy equal to that of topical triamcinolone acetonide 0.1% paste. For vulvovaginal lichen planus, pimecrolimus was superior to placebo in one double-blind study, and tacrolimus was effective in open studies. Only case reports support the efficacy of topical calcineurin inhibitors in cutaneous lichen planus.

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Titarenko, M. A., V. A. Stolyarova, P. G. Sysolyatin, and O. D. Baydik. "The role of gastrointestinal pathology in the development and severity of oral lichen planus." Bulletin of Siberian Medicine 17, no. 3 (September 29, 2018): 151–56. http://dx.doi.org/10.20538/1682-0363-2018-3-151-156.

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The aim is to determine the most significant predictors of the oral lichen planus in patients with gastrointestinal pathology.Materials and methods. The study was performed of 40 patients aged 41 to 86 years with oral lichen planus. Degree of mucosal damage by oral lichen planus was evaluated. The concomitant pathology of the gastrointestinal tract was established. A discriminant analysis was carried out.Results. The most significant predictors for a diagnosis of oral lichen planus in patients with gastrointestinal pathology are revealed. The sensitivity of the method was 100.0%, the specificity was 100.0%, and the errorfreeness was 100.0%.The conclusion. Discriminant analysis allows us to conduct a diagnosis of the oral lichen planus in patients with gastrointestinal pathology. This model is available in clinical practice.

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Bastos Gomes, Antonio Carlos, César Bimbi, and Piotr Brzezinski. "Lichen planus pigmentosus inversus associated with oral lichen planus." Our Dermatology Online 11, no. 2 (April 2, 2020): 156–57. http://dx.doi.org/10.7241/ourd.20202.10.

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Li, Xin, and Zhiqiang Wang. "Mechanisms of reactive oxygen species in oral lichen planus: A literature review." European Journal of Inflammation 20 (January 2022): 1721727X2211043. http://dx.doi.org/10.1177/1721727x221104389.

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Oral lichen planus is a chronic non-infectious mucosal inflammatory disease caused by an imbalance between reactive oxygen species homeostasis and antioxidant defense systems. Notably, excessive oxidative stress products result in related autoimmune reactions. Further, it activates signaling pathways related to the development of oral lichen planus, as evidenced by the detection of damage to deoxyribonucleic acid, protein, and lipid. Thus, the mechanisms of reactive oxygen species-mediated oxidative stress in the pathogenesis of oral lichen planus are numerous and complex. In this review, we first introduce oxidative stress and oxidative products. Then, we summarize the role and possible mechanisms of reactive oxygen species-mediated oxidative stress in the pathogenesis of oral lichen planus and present a clinical correlation between oxidative stress and oral lichen planus. Finally, we discuss the current challenges and future perspectives.

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Stoopler, Eric T., Sausan Alfaris, Dalal Alomar, and Faizan Alawi. "Oral lichen planus preceding concomitant lichen planopilaris." Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology 122, no. 3 (September 2016): e82-e85. http://dx.doi.org/10.1016/j.oooo.2016.05.022.

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Orekhova, L. Yu, M. V. Osipova, and А. А. Ladyko. "Model of development, prevention and treatment of oral lichen planus. Part II." Parodontologiya 24, no. 1 (February 10, 2019): 57–62. http://dx.doi.org/10.25636/pmp.1.2019.1.10.

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Relevance. Currently, system-wide patterns of development, progression of oral lichen planus have not been studied enough. The questions of substantiation of expedient therapeutic and prophylactic measures for this disease with characteristic risk factors have not been worked out in many respects.Purpose. Identifcation of new system-wide regularities of oral lichen planus based on the development of a model for its development, prevention and treatment.Materials and methods. The study design included: the development of a model for the development, progression, prevention and treatment of oral lichen planus; clinical dental examination of 350 patients with oral lichen planus (the diagnosis was made on the basis of clinical data and the results of ﬂuorescent diagnostics); evaluation of the effectiveness of a set of measures, including the prescription of drugs (Imudon, Kudesan, Tenoten).Results. New system-wide regularities of lichen planus are revealed. For the frst time, the relative frequencies and intensities of transitions of various forms of lichen planus from one to another are estimated. A method is proposed for estimating the moment of saturation of the therapeutic and prophylactic effect of a complex of measures on the oral mucosa with lichen planus using ﬂuorescent diagnostics. The temporal characteristics of this moment were determined during the performance of the therapeutic and prophylactic complex.Summary. The developed model will allow, without signifcant time and material costs, justify therapeutic and prophylactic measures that are expedient for various groups of the population in case of oral lichen planus of the oral mucosa.

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Zamani, Farhad, Mehran Haghighi, Mohammad Roshani, and Masoudreza Sohrabi. "Esophageal Lichen Planus Stricture." Middle East Journal of Digestive Diseases 11, no. 1 (November 15, 2018): 52–54. http://dx.doi.org/10.15171/mejdd.2018.128.

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Lichen planus is a dermatologic chronic inflammatory disease that usually involved the skin and mucosa. Esophageal lichen planus with stricture is rare presentation of this disease. It is usually associated with oral mucosal involvement and commonly presenting in middle-age female. In present case, we describe a 48-year-old woman with history of oral lichen planus who referred to us for progressive dysphagia for solid food .She had not history of other causes of dysphagia. Upper endoscopy revealed a benign stricture located in proximal of esophagus that comparable with lichen planus features. The patient underwent three sessions of wireguided bougie dilation that improved her symptoms totally. Lichen planus has to be considered in differential diagnosis in patients with dysphagia.

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Shah, Syed Murad Ali, Muhammad Ilyas, and Jawad Ahmad Kundi. "The Clinical Profile of Oral Lichen Planus." Journal of Gandhara Medical and Dental Science 3, no. 01 (September 1, 2016): 27–31. http://dx.doi.org/10.37762/jgmds.3-01.45.

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OBJECTIVESThe objective of the study was to determine the clinical profile of oral lichen planus.METHODOLOGYThis retrospective cohort study was carried from January 2011 to December 2015 at the Department of Oral and Maxillofacial Surgery, Sardar Begum Dental College, Peshawar.A total of 36 with 14 male and 22 female patients having oral lichen planus from were selected. On defined and population-based sample the age selected was ≥ 20 years and divided into four categories i.e..,20-29 years,30-39 years,40-49 years and 50-59 years. The diagnostic criteria proposed by van der Meij et al 23 in 2003 based on the WHO definition of oral lichen planus were used to identify the cases of oral lichen planus.That entire patient’s with incomplete records and aged > 60 years were excluded. The data was analyzed through SPSS 22 at the significance level of p < 0.05 and Chi-square statistics was applied for site and gender association.RESULTSThe mean age presentation was 39.2 (SD± 15.49) years. The female to male ratio was 1:57:1. The dominant aged group was 30-39 years with n=16 (44.44%).The buccal mucosa was the most common site involved n=28(77.8%).Reticular type of oral lichen planus was the most common form and was present in n=22(61.1%) patients however, bilaterally involved mucosa was commonly seen. Chi-square statistics showed a significant association between bilateral involvement of oral mucosa in oral lichen planus with both male and female (x2= 5.833, p= 0.016).CONCLUSIONThe most common site involved in oral lichen planus was buccal mucosa, most common form was atrophic with female predominance and bilaterally involved oral mucosa was significantly associated with gender.

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